Page last updated: 2024-10-29

isoflurane and Neuromuscular Blockade

isoflurane has been researched along with Neuromuscular Blockade in 48 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Neuromuscular Blockade: The intentional interruption of transmission at the NEUROMUSCULAR JUNCTION by external agents, usually neuromuscular blocking agents. It is distinguished from NERVE BLOCK in which nerve conduction (NEURAL CONDUCTION) is interrupted rather than neuromuscular transmission. Neuromuscular blockade is commonly used to produce MUSCLE RELAXATION as an adjunct to anesthesia during surgery and other medical procedures. It is also often used as an experimental manipulation in basic research. It is not strictly speaking anesthesia but is grouped here with anesthetic techniques. The failure of neuromuscular transmission as a result of pathological processes is not included here.

Research Excerpts

ExcerptRelevanceReference
"The aim of the present study was to compare the influence of volatile anesthetics on transcranial motor-evoked potentials (tcMEP) in humans anesthetized with propofol/fentanyl/nitrous oxide and on partial neuromuscular blockade (NMB)."9.12The effects of volatile anesthetics on intraoperative monitoring of myogenic motor-evoked potentials to transcranial electrical stimulation and on partial neuromuscular blockade during propofol/fentanyl/nitrous oxide anesthesia in humans. ( Goto, F; Ishizeki, J; Kubo, K; Nishikawa, K; Saito, S; Sekimoto, K, 2006)
"Nimodipine, a calcium channel blocking drug, is used in the treatment of cerebral arterial spasm after subarachnoid haemorrhage due to bleeding from an intracranial aneurysm."9.09The effects of nimodipine on vecuronium-induced neuromuscular blockade. ( Aysel, I; Balcioglu, T; Hepaguşlar, H; Uyar, M, 2000)
" We hypothesised that there was a difference in the rate of reversal of rocuronium-induced neuromuscular blockade based on the selection of inhalation agent."9.09A comparison of antagonism of rocuronium-induced neuromuscular blockade during sevoflurane and isoflurane anaesthesia. ( Maslow, A; Murphy, CM; Shorten, GD; Sutcliffe, DG; Uppington, J, 2000)
" After induction of anaesthesia with etomidate and fentanyl, neuromuscular blockade was monitored by recording the electromyographic response of the adductor pollicis muscle to a supramaximal train-of-four (TOF) stimulation of the ulnar nerve at 2 Hz for 2 s at 20-s intervals."9.08Comparison of time course of neuromuscular blockade in young children following rocuronium and atracurium. ( Marichal, A; Ribeiro, FC; Scheiber, G, 1998)
"1 % isoflurane anesthesia, response was determined when the tail clamp was applied at several points after microinjection of pancuronium into the lateral ventricle."7.83Pancuronium enhances isoflurane anesthesia in rats via inhibition of cerebral nicotinic acetylcholine receptors. ( Hobo, S; Miyano, K; Miyazaki, Y; Sunaga, H; Uezono, S, 2016)
" The authors present three alternative strategies including the inhalation of anaesthetic agents, helium/ oxygen ventilation, and extracorporeal membrane oxygenation which may be beneficial when "conventional therapies' fail in the intubated patient with status asthmaticus."7.69Therapeutic options for severe, refractory status asthmaticus: inhalational anaesthetic agents, extracorporeal membrane oxygenation and helium/oxygen ventilation. ( Garrett, JS; Tobias, JD, 1997)
"Remifentanil was started before induction with propofol and succinylcholine."6.73Dosing of remifentanil to prevent movement during craniotomy in the absence of neuromuscular blockade. ( Bakri, MH; Deogaonkar, A; Ebrahim, Z; Foss, J; Lotto, M; Mascha, E; Maurtua, MA; Na, J; Schubert, A; Sessler, DI, 2008)
"This study evaluated the use of sugammadex for reversal of profound neuromuscular blockade induced with rocuronium or vecuronium in dogs."5.16Reversal of profound rocuronium or vecuronium-induced neuromuscular block with sugammadex in isoflurane-anaesthetised dogs. ( Auer, U; Hunter, JM; Jones, RS; Mosing, M; West, E, 2012)
"Propofol or remifentanil anesthesia was associated with a higher incidence of OCR during pediatric strabismus surgery than sevoflurane and desflurane anesthesia, when either ketamine or midazolam was used as an induction agent."5.14Effect of different anesthetic agents on oculocardiac reflex in pediatric strabismus surgery. ( Choi, SR; Chung, CJ; Lee, JH; Lee, SC; Park, SW, 2009)
"The aim of the present study was to compare the influence of volatile anesthetics on transcranial motor-evoked potentials (tcMEP) in humans anesthetized with propofol/fentanyl/nitrous oxide and on partial neuromuscular blockade (NMB)."5.12The effects of volatile anesthetics on intraoperative monitoring of myogenic motor-evoked potentials to transcranial electrical stimulation and on partial neuromuscular blockade during propofol/fentanyl/nitrous oxide anesthesia in humans. ( Goto, F; Ishizeki, J; Kubo, K; Nishikawa, K; Saito, S; Sekimoto, K, 2006)
"To investigate the onset and duration of neuromuscular blockade of rocuronium bromide and its associated haemodynamic effects at three doses in healthy horses."5.12Observations on the muscle relaxant rocuronium bromide in the horse--a dose-response study. ( Auer, U; Mosing, M; Uray, C, 2007)
"Nimodipine, a calcium channel blocking drug, is used in the treatment of cerebral arterial spasm after subarachnoid haemorrhage due to bleeding from an intracranial aneurysm."5.09The effects of nimodipine on vecuronium-induced neuromuscular blockade. ( Aysel, I; Balcioglu, T; Hepaguşlar, H; Uyar, M, 2000)
" After induction of anaesthesia with etomidate and fentanyl, neuromuscular blockade was monitored by recording the electromyographic response of the adductor pollicis muscle to a supramaximal train-of-four (TOF) stimulation of the ulnar nerve at 2 Hz for 2 s at 20-s intervals."5.08Comparison of time course of neuromuscular blockade in young children following rocuronium and atracurium. ( Marichal, A; Ribeiro, FC; Scheiber, G, 1998)
"The cardiovascular effects of Org 9487 during isoflurane anaesthesia have been evaluated using three doses around its ED90 for neuromuscular blockade, i."5.08Cardiovascular effects of Org 9487 under isoflurane anaesthesia in man. ( Hempelmann, G; Osmer, C; Vögele, C; Wulf, K; Zickmann, B, 1998)
"1 % isoflurane anesthesia, response was determined when the tail clamp was applied at several points after microinjection of pancuronium into the lateral ventricle."3.83Pancuronium enhances isoflurane anesthesia in rats via inhibition of cerebral nicotinic acetylcholine receptors. ( Hobo, S; Miyano, K; Miyazaki, Y; Sunaga, H; Uezono, S, 2016)
"We conclude that partial neuromuscular blockade with mivacurium permits intraoperative facial nerve monitoring."3.74Partial neuromuscular blockage levels with mivacurium during mastoidectomy allows intraoperative facial nerve monitoring. ( Alatas, N; Baysal, Z; Cengiz, M; Ganidagli, S; San, I, 2008)
" General anaesthesia and neuromuscular blockade were induced with thiamylal and vecuronium."3.69Temperatures measured by a deep body thermometer (Coretemp) compared with tissue temperatures measured at various depths using needles placed into the sole of the foot. ( Kashimoto, S; Kumazawa, T; Matsukawa, T; Ozaki, M; Shindo, S, 1996)
" The authors present three alternative strategies including the inhalation of anaesthetic agents, helium/ oxygen ventilation, and extracorporeal membrane oxygenation which may be beneficial when "conventional therapies' fail in the intubated patient with status asthmaticus."3.69Therapeutic options for severe, refractory status asthmaticus: inhalational anaesthetic agents, extracorporeal membrane oxygenation and helium/oxygen ventilation. ( Garrett, JS; Tobias, JD, 1997)
"Remifentanil was started before induction with propofol and succinylcholine."2.73Dosing of remifentanil to prevent movement during craniotomy in the absence of neuromuscular blockade. ( Bakri, MH; Deogaonkar, A; Ebrahim, Z; Foss, J; Lotto, M; Mascha, E; Maurtua, MA; Na, J; Schubert, A; Sessler, DI, 2008)
"Rocuronium is an effective nondepolarizing muscle relaxant in the cat under the clinical conditions of this study."2.72A clinical study of the effects of rocuronium in isoflurane-anaesthetized cats. ( Auer, U; Mosing, M, 2006)
"Rocuronium onset was prolonged by 67% (p = 0."2.72The effect of desflurane on rocuronium onset, clinical duration and maintenance requirements. ( Brull, SJ; Gan, TJ; Glass, PS; Silverman, DG; Stout, RG, 2006)
"To compare the pharmacokinetic behaviour of doxacurium in patients undergoing normothermic or hypothermic cardiopulmonary bypass (CPB) for coronary artery bypass graft surgery."2.69Pharmacokinetics of doxacurium during normothermic and hypothermic cardiopulmonary bypass surgery. ( Asokumar, B; Cheng, D; Chung, F; Peniston, C; Sandler, A; Varin, F, 1998)
"Rocuronium was administered in increments of 100 micrograms."2.69Neuromuscular blocking effects of rocuronium during desflurane, isoflurane, and sevoflurane anaesthesia. ( Ledowski, T; Linstedt, U; Proppe, D; Sitzlack, D; Wulf, H, 1998)
"The dose-response and concentration-response relation of rocuronium infusion was studied in 20 adult surgical patients during propofol-nitrous oxide and isoflurane (1 MAC)-nitrous oxide anaesthesia."2.68Dose-response and concentration-response relation of rocuronium infusion during propofol-nitrous oxide and isoflurane-nitrous oxide anaesthesia. ( Kansanaho, M; Olkkola, KT; Wierda, JM, 1997)
"When rocuronium was applied at higher concentrations (IC25 and IC50), sevoflurane had an effect similar to that of isoflurane."1.39Synergistic effect of sevoflurane and isoflurane on inhibition of the adult-type muscle nicotinic acetylcholine receptor by rocuronium. ( Cao, J; Li, W; Liu, L; Luo, J; Min, S; Wang, B; Wei, K, 2013)
"Atracurium was administered via a continuous infusion in order to obtain 85% twitch depression of the control value assessed by repeated accelerometric stimulation at the adductor pollicis."1.33Acute desflurane or sevoflurane exposure on a previously stabilized atracurium-induced neuromuscular block. ( Beaussier, M; Boughaba, A; d'Hollander, A; Debaene, B; Lienhart, A; Schiffer, E, 2006)
"kg-1 and construction of dose-response curves (n = 72)."1.30Potency and time course of mivacurium block during sevoflurane, isoflurane and intravenous anesthesia. ( Carroll, MT; Hughes, DA; Lowry, DW; McCarthy, GJ; Mirakhur, RK; O'Hare, RA, 1999)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (33.33)18.2507
2000's20 (41.67)29.6817
2010's10 (20.83)24.3611
2020's2 (4.17)2.80

Authors

AuthorsStudies
Ida, KK2
Van-Wijnsberghe, AS1
Tutunaru, A2
Limpens, V1
Sauvage, A1
Serteyn, D1
Sandersen, C2
Van Wijnsberghe, AS1
Dmitrovic, P1
Fuchs-Buder, T1
Baumann, C1
De Guis, J1
Guerci, P1
Meistelman, C1
Lorenzutti, AM2
Martin-Flores, M2
Baldivieso, JM1
Himelfarb, MA1
Litterio, NJ2
McKay, RE1
Hall, KT1
Hills, N1
Miyazaki, Y1
Sunaga, H1
Hobo, S1
Miyano, K1
Uezono, S1
Rossetti, VL1
Zarazaga, MP1
Bonetto, CC1
Aguirre, GE1
Putz, L1
Dransart, C1
Jamart, J1
Marotta, ML1
Delnooz, G1
Dubois, PE1
Eikermann, M1
Zaremba, S1
Malhotra, A1
Jordan, AS1
Rosow, C1
Chamberlin, NL1
Maurtua, MA1
Deogaonkar, A1
Bakri, MH1
Mascha, E1
Na, J1
Foss, J1
Sessler, DI1
Lotto, M1
Ebrahim, Z1
Schubert, A2
Choi, SR1
Park, SW1
Lee, JH1
Lee, SC1
Chung, CJ1
Saitoh, Y4
Oshima, T1
Nakata, Y1
Schwartz, AE1
Mosing, M3
Auer, U3
West, E1
Jones, RS1
Hunter, JM1
Liu, L1
Li, W1
Wei, K1
Cao, J1
Luo, J1
Wang, B1
Min, S1
Detsch, O1
Kochs, E1
Siemers, M1
Bromm, B1
Vahle-Hinz, C1
Santanen, OA1
Svartling, N1
Haasio, J1
Paloheimo, MP1
Ledowski, T2
Wulf, H2
Ahrens, K1
Weindlmayr-Goettel, M1
Kress, HG1
Geldner, G1
Scholz, J1
Rapp, HJ1
Altenmueller, CA1
Waschke, C1
Maidatsi, PG1
Zaralidou, AT1
Gorgias, NK1
Amaniti, EN1
Karakoulas, KA1
Giala, MM1
Sekimoto, K1
Nishikawa, K1
Ishizeki, J1
Kubo, K1
Saito, S1
Goto, F1
Beaussier, M1
Boughaba, A1
Schiffer, E1
Debaene, B1
Lienhart, A1
d'Hollander, A1
Farag, E1
Chelune, GJ1
Mascha, EJ1
Stout, RG1
Gan, TJ1
Glass, PS1
Silverman, DG1
Brull, SJ1
Uray, C1
Cengiz, M1
Ganidagli, S1
Alatas, N1
San, I1
Baysal, Z1
Matsukawa, T1
Kashimoto, S1
Ozaki, M1
Shindo, S1
Kumazawa, T1
Nott, MR1
Halfacre, J1
Tobias, JD1
Garrett, JS1
Jalkanen, L1
Meretoja, OA1
Koitabashi, Y1
Makita, K3
Tanaka, H3
Amaha, K3
Kansanaho, M1
Olkkola, KT1
Wierda, JM1
Ribeiro, FC1
Scheiber, G1
Marichal, A1
Asokumar, B1
Cheng, D1
Chung, F1
Peniston, C1
Sandler, A1
Varin, F1
Linstedt, U1
Proppe, D1
Sitzlack, D1
Keller, C1
Sparr, HJ1
Luger, TJ1
Brimacombe, J1
Fujii, Y2
Lowry, DW2
Mirakhur, RK2
McCarthy, GJ2
Carroll, MT2
McCourt, KC1
Osmer, C1
Wulf, K1
Vögele, C1
Zickmann, B1
Hempelmann, G1
Everett, LL1
Hughes, DA1
O'Hare, RA1
St Pierre, M1
Landsleitner, B1
Schwilden, H1
Schuettler, J1
Aysel, I1
Hepaguşlar, H1
Balcioglu, T1
Uyar, M1
Sutcliffe, DG1
Murphy, CM1
Maslow, A1
Uppington, J1
Shorten, GD1
Jellish, WS1
Brody, M1
Sawicki, K1
Slogoff, S1
Ortiz Gómez, J1
Percaz Bados, J1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Weight-based Versus External Ear-size Based Technique for Selection of Laryngeal Mask Airway in Pediatric Surgical Patients.[NCT03931122]136 participants (Anticipated)Interventional2019-12-11Recruiting
Effect of Deep Curarisation and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity in Patients Undergoing Laparoscopic Gastric Bypass Surgery[NCT01748643]Phase 460 participants (Actual)Interventional2013-04-30Completed
Visualization of Regional Lung Ventilation During Neostigmine or Sugammadex Enhanced Recovery From Moderate Residual Neuromuscular Blockade in the Anaesthetized Rat Using Functional Respiratory Imaging[NCT02284412]Phase 413 participants (Actual)Interventional2014-12-31Completed
Pharmacokinetic and Pharmacodynamic of Rocuronium Bromide Measured in Adductor Pollicis and Masseter Muscles.[NCT02376595]10 participants (Actual)Observational2013-03-31Completed
Comparison of Two Different Anesthetic Techniques on Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg Position: A Prospective Randomized Clinical Trial[NCT03572517]65 participants (Actual)Interventional2017-09-01Completed
Effect of Depth of Total Intravenous Anesthesia Using Propofol on Postoperative Cognitive Dysfunction : A Multi-Center Study[NCT01708837]Phase 4300 participants (Anticipated)Interventional2012-10-31Active, not recruiting
Pressure Support Ventilation Versus Continuous Positive Air Way Pressure (CPAP) Using I Gel Laryngeal Mask for Minor Surgery in Adult Patients, a Prospective cross_over Study[NCT05116839]38 participants (Anticipated)Interventional2019-03-31Recruiting
Comparison of the Effect of Continuous Infusion and Bolus Doses of Rocuronium During Anesthesia for Lumbal Discectomy on Muscle Strength and Quality of Patient Recovery[NCT04236050]80 participants (Actual)Interventional2015-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Duration of Surgery

Measured from the time of first skin incision to completion of skin closure. (NCT01748643)
Timeframe: Participants will be followed for the duration of the laparoscopic gastric bypass surgery, an expected average of 1.5h

Interventionminutes (Mean)
Deep Neuromuscular Blockade, Reversal With Sugammadex61.3
Normal Neuromuscular Blockade, Reversal With Neostigmine70.6

Forced Expiratory Volume in 1 Second

Forced expiratory volume in 1 second is measured with the Vitalograph® electronic portable peak flow meter. A mean of 3 measurements in the upright posture in bed before and after surgery will be used. (NCT01748643)
Timeframe: Measured the day before surgery and 30min after completion of surgery (when the modified observer's assessment of alertness/sedation scale is 5 (Patient responds readily to name spoken in normal tone))

Interventionpercent change from baseline (Mean)
Deep Neuromuscular Blockade, Reversal With Sugammadex45.2
Normal Neuromuscular Blockade, Reversal With Neostigmine48.8

Forced Vital Capacity

Forced vital capacity is measured with the Vitalograph® electronic portable peak flow meter. A mean of 3 measurements in the upright posture in bed before and after surgery will be used. (NCT01748643)
Timeframe: Measured the day before surgery and 30min after completion of surgery (when the modified observer's assessment of alertness/sedation scale is 5 (Patient responds readily to name spoken in normal tone))

Interventionpercent change from baseline (Mean)
Deep Neuromuscular Blockade, Reversal With Sugammadex51.9
Normal Neuromuscular Blockade, Reversal With Neostigmine49.0

Number of Intra-abdominal Pressure Rises > 18cmH2O

The number of intra-abdominal pressure rises > 18cmH2O detected by the intra-abdominal CO2 insufflator. (NCT01748643)
Timeframe: Participants will be followed for the duration of the laparoscopic gastric bypass surgery, an expected average of 1.5h

Interventionnumber of intra-abdominal pressure rises (Mean)
Deep Neuromuscular Blockade, Reversal With Sugammadex0.2
Normal Neuromuscular Blockade, Reversal With Neostigmine0.3

Peak Expiratory Flow

Peak expiratory flow is measured with the Vitalograph® electronic portable peak flow meter. A mean of 3 measurements in the upright posture in bed before and after surgery will be used. (NCT01748643)
Timeframe: Measured the day before surgery and 30min after completion of surgery (when the modified observer's assessment of alertness/sedation scale is 5 (Patient responds readily to name spoken in normal tone))

Interventionpercent change from baseline (Mean)
Deep Neuromuscular Blockade, Reversal With Sugammadex51.3
Normal Neuromuscular Blockade, Reversal With Neostigmine51.5

Subjective Evaluation of the View on the Operating Field by the Surgeon

"At the end of surgery, the view on the operating field will be graded by the surgeon using a 5-point rating scale:~Extremely poor~Poor~Acceptable~Good~Optimal" (NCT01748643)
Timeframe: Participants will be followed for the duration of the laparoscopic gastric bypass surgery, an expected average of 1.5h

Interventionunits on a scale (Mean)
Deep Neuromuscular Blockade, Reversal With Sugammadex4.2
Normal Neuromuscular Blockade, Reversal With Neostigmine3.9

Reviews

1 review available for isoflurane and Neuromuscular Blockade

ArticleYear
Newer drugs in pediatric anesthesia.
    Seminars in pediatric surgery, 1999, Volume: 8, Issue:1

    Topics: Anesthesiology; Anesthetics; Anesthetics, Inhalation; Child; Desflurane; Humans; Isoflurane; Methyl

1999

Trials

32 trials available for isoflurane and Neuromuscular Blockade

ArticleYear
Low-dose neostigmine to antagonise shallow atracurium neuromuscular block during inhalational anaesthesia: A randomised controlled trial.
    European journal of anaesthesiology, 2013, Volume: 30, Issue:10

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Atracurium; Chol

2013
Evaluation of neostigmine antagonism at different levels of vecuronium-induced neuromuscular blockade in isoflurane anesthetized dogs.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2014, Volume: 55, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Dogs; Female; Isoflurane; Male; Neostigmine; Neuromuscular Blockad

2014
The Effect of Anesthetic Choice (Sevoflurane Versus Desflurane) and Neuromuscular Management on Speed of Airway Reflex Recovery.
    Anesthesia and analgesia, 2016, Volume: 122, Issue:2

    Topics: Accelerometry; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Androstanols; Anesthesia Rec

2016
Speed of reversal of vecuronium neuromuscular block with different doses of neostigmine in anesthetized dogs.
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Cross-Over Studies; Dogs; Female; Isoflurane; Male; Neostigmine; N

2017
Operating room discharge after deep neuromuscular block reversed with sugammadex compared with shallow block reversed with neostigmine: a randomized controlled trial.
    Journal of clinical anesthesia, 2016, Volume: 35

    Topics: Adult; Androstanols; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Desfl

2016
Dosing of remifentanil to prevent movement during craniotomy in the absence of neuromuscular blockade.
    Journal of neurosurgical anesthesiology, 2008, Volume: 20, Issue:4

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; Brady

2008
Effect of different anesthetic agents on oculocardiac reflex in pediatric strabismus surgery.
    Journal of anesthesia, 2009, Volume: 23, Issue:4

    Topics: Androstanols; Anesthesia; Anesthesia, General; Anesthetics; Anesthetics, Dissociative; Anesthetics,

2009
Acceleromyographic monitoring of neuromuscular block over the orbicularis oris muscle in anesthetized patients receiving vecuronium.
    Journal of clinical anesthesia, 2010, Volume: 22, Issue:5

    Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthetics, Inhalation; Electromyography; Facial Muscles; Facia

2010
Reversal of profound rocuronium or vecuronium-induced neuromuscular block with sugammadex in isoflurane-anaesthetised dogs.
    Veterinary journal (London, England : 1997), 2012, Volume: 192, Issue:3

    Topics: Androstanols; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dogs; Dose-Response Relation

2012
Neuromuscular block and relative concentrations of mivacurium isomers under isoflurane versus propofol anaesthesia.
    European journal of anaesthesiology, 2003, Volume: 20, Issue:10

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Dose-Response R

2003
Neuromuscular recovery following rocuronium bromide single dose in infants.
    Paediatric anaesthesia, 2004, Volume: 14, Issue:4

    Topics: Age Factors; Analgesia, Epidural; Analysis of Variance; Androstanols; Anesthesia Recovery Period; An

2004
Rocuronium duration of action under sevoflurane, desflurane or propofol anaesthesia.
    European journal of anaesthesiology, 2004, Volume: 21, Issue:10

    Topics: Abdomen; Adult; Androstanols; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalati

2004
The effects of volatile anesthetics on intraoperative monitoring of myogenic motor-evoked potentials to transcranial electrical stimulation and on partial neuromuscular blockade during propofol/fentanyl/nitrous oxide anesthesia in humans.
    Journal of neurosurgical anesthesiology, 2006, Volume: 18, Issue:2

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Inhalation; Evoked Potentials, Motor; Female; Fentany

2006
A clinical study of the effects of rocuronium in isoflurane-anaesthetized cats.
    Veterinary anaesthesia and analgesia, 2006, Volume: 33, Issue:4

    Topics: Androstanols; Anesthesia, General; Anesthetics, Inhalation; Animals; Cats; Female; Heart Rate; Injec

2006
Is depth of anesthesia, as assessed by the Bispectral Index, related to postoperative cognitive dysfunction and recovery?
    Anesthesia and analgesia, 2006, Volume: 103, Issue:3

    Topics: Adjuvants, Anesthesia; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Cognition; Female

2006
Is depth of anesthesia, as assessed by the Bispectral Index, related to postoperative cognitive dysfunction and recovery?
    Anesthesia and analgesia, 2006, Volume: 103, Issue:3

    Topics: Adjuvants, Anesthesia; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Cognition; Female

2006
Is depth of anesthesia, as assessed by the Bispectral Index, related to postoperative cognitive dysfunction and recovery?
    Anesthesia and analgesia, 2006, Volume: 103, Issue:3

    Topics: Adjuvants, Anesthesia; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Cognition; Female

2006
Is depth of anesthesia, as assessed by the Bispectral Index, related to postoperative cognitive dysfunction and recovery?
    Anesthesia and analgesia, 2006, Volume: 103, Issue:3

    Topics: Adjuvants, Anesthesia; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Cognition; Female

2006
The effect of desflurane on rocuronium onset, clinical duration and maintenance requirements.
    Acta anaesthesiologica Belgica, 2006, Volume: 57, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Androstanols; Anesthesia Recovery Period; Anes

2006
Observations on the muscle relaxant rocuronium bromide in the horse--a dose-response study.
    Veterinary anaesthesia and analgesia, 2007, Volume: 34, Issue:2

    Topics: Androstanols; Anesthesia, General; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Dru

2007
The influence of the duration of isoflurane anaesthesia on neuromuscular effects of mivacurium.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:2

    Topics: Anesthesia; Anesthetics, Inhalation; Child; Child, Preschool; Electromyography; Humans; Infant; Isof

1997
Train-of-four and double burst stimulation fade at the great toe and thumb.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:4

    Topics: Adult; Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Electric Stimulation

1997
Dose-response and concentration-response relation of rocuronium infusion during propofol-nitrous oxide and isoflurane-nitrous oxide anaesthesia.
    European journal of anaesthesiology, 1997, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia, General; Anesthetics, Combined; Anesthetics, Inha

1997
Comparison of time course of neuromuscular blockade in young children following rocuronium and atracurium.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:3

    Topics: Analysis of Variance; Androstanols; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics

1998
Pharmacokinetics of doxacurium during normothermic and hypothermic cardiopulmonary bypass surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:6

    Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Body Temperature; Cardiopulmonary Bypass; C

1998
Neuromuscular blocking effects of rocuronium during desflurane, isoflurane, and sevoflurane anaesthesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:6

    Topics: Adult; Androstanols; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; An

1998
Patient outcomes with positive pressure versus spontaneous ventilation in non-paralysed adults with the laryngeal mask.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:6

    Topics: Adult; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Carbon Dioxide

1998
Modified double burst stimulation of varying stimulating currents.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:7

    Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Anesthetics, Inhalation; Electric Stimulati

1998
Neuromuscular effects of rocuronium during sevoflurane, isoflurane, and intravenous anesthesia.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:4

    Topics: Adult; Androstanols; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Dru

1998
Post-tetanic burst count and train-of-four during recovery from vecuronium-induced intense neuromuscular block under different types of anaesthesia.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:5

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Inhalat

1998
Cardiovascular effects of Org 9487 under isoflurane anaesthesia in man.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:5

    Topics: Adult; Anesthetics, Inhalation; Blood Pressure; Dose-Response Relationship, Drug; Evaluation Studies

1998
The effects of nimodipine on vecuronium-induced neuromuscular blockade.
    European journal of anaesthesiology, 2000, Volume: 17, Issue:6

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Calcium Channel Block

2000
A comparison of antagonism of rocuronium-induced neuromuscular blockade during sevoflurane and isoflurane anaesthesia.
    Anaesthesia, 2000, Volume: 55, Issue:10

    Topics: Adult; Androstanols; Anesthesia Recovery Period; Anesthetics, Inhalation; Female; Humans; Isoflurane

2000
Recovery from neuromuscular blockade after either bolus and prolonged infusions of cisatracurium or rocuronium using either isoflurane or propofol-based anesthetics.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Androstanols; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Female; Humans; Infusio

2000
[The effect of anesthetic technique on recovery from neuromuscular blockade with cisatracurium].
    Revista espanola de anestesiologia y reanimacion, 2001, Volume: 48, Issue:3

    Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Atracurium

2001

Other Studies

15 other studies available for isoflurane and Neuromuscular Blockade

ArticleYear
Onset and duration of cis-atracurium neuromuscular block during fentanyl and lidocaine infusions in isoflurane-anaesthetised dogs.
    The Veterinary record, 2020, Sep-05, Volume: 187, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Atracurium; Dogs; Female; Fentanyl; Infusions, Intravenous; Isoflur

2020
Neuromuscular blockade effects of cisatracurium in 11 cats undergoing ophthalmological surgery anaesthetised with isoflurane.
    Journal of feline medicine and surgery, 2022, Volume: 24, Issue:4

    Topics: Anesthetics; Animals; Atracurium; Cat Diseases; Cats; Isoflurane; Neuromuscular Blockade; Neuromuscu

2022
Pancuronium enhances isoflurane anesthesia in rats via inhibition of cerebral nicotinic acetylcholine receptors.
    Journal of anesthesia, 2016, Volume: 30, Issue:4

    Topics: Anesthesia; Anesthetics; Animals; Isoflurane; Male; Neuromuscular Blockade; Neuromuscular Blocking A

2016
Neostigmine but not sugammadex impairs upper airway dilator muscle activity and breathing.
    British journal of anaesthesia, 2008, Volume: 101, Issue:3

    Topics: Androstanols; Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Cholinesterase Inhibitor

2008
Neostigmine but not sugammadex impairs upper airway dilator muscle activity and breathing.
    British journal of anaesthesia, 2008, Volume: 101, Issue:3

    Topics: Androstanols; Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Cholinesterase Inhibitor

2008
Neostigmine but not sugammadex impairs upper airway dilator muscle activity and breathing.
    British journal of anaesthesia, 2008, Volume: 101, Issue:3

    Topics: Androstanols; Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Cholinesterase Inhibitor

2008
Neostigmine but not sugammadex impairs upper airway dilator muscle activity and breathing.
    British journal of anaesthesia, 2008, Volume: 101, Issue:3

    Topics: Androstanols; Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Cholinesterase Inhibitor

2008
Muscle relaxants and electroencephalogram.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Animals; Dogs; Electroencephalography; Isoflurane; Neostigmine; Neuromuscular Blockade; Neuromuscula

2011
Synergistic effect of sevoflurane and isoflurane on inhibition of the adult-type muscle nicotinic acetylcholine receptor by rocuronium.
    Journal of anesthesia, 2013, Volume: 27, Issue:3

    Topics: Acetylcholine; Androstanols; Anesthetics, Inhalation; Cell Line; Drug Synergism; HEK293 Cells; Human

2013
Differential effects of isoflurane on excitatory and inhibitory synaptic inputs to thalamic neurones in vivo.
    British journal of anaesthesia, 2002, Volume: 89, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Bicuculline; Evoked Potentials, Somatosensory; Isoflurane; Neuromu

2002
Neural nets and prediction of the recovery rate from neuromuscular block.
    European journal of anaesthesiology, 2003, Volume: 20, Issue:2

    Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Electromyography; Humans;

2003
Acute desflurane or sevoflurane exposure on a previously stabilized atracurium-induced neuromuscular block.
    European journal of anaesthesiology, 2006, Volume: 23, Issue:9

    Topics: Adult; Anesthetics, Inhalation; Atracurium; Calibration; Desflurane; Female; Humans; Isoflurane; Mal

2006
Partial neuromuscular blockage levels with mivacurium during mastoidectomy allows intraoperative facial nerve monitoring.
    ORL; journal for oto-rhino-laryngology and its related specialties, 2008, Volume: 70, Issue:4

    Topics: Adolescent; Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Ear Diseases; Electric Stimulati

2008
Temperatures measured by a deep body thermometer (Coretemp) compared with tissue temperatures measured at various depths using needles placed into the sole of the foot.
    European journal of anaesthesiology, 1996, Volume: 13, Issue:4

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Body Temperature; Equipment

1996
Anaesthesia for dental conservation in a patient with tuberous sclerosis.
    European journal of anaesthesiology, 1996, Volume: 13, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; D

1996
Therapeutic options for severe, refractory status asthmaticus: inhalational anaesthetic agents, extracorporeal membrane oxygenation and helium/oxygen ventilation.
    Paediatric anaesthesia, 1997, Volume: 7, Issue:1

    Topics: Anesthetics, Inhalation; Child; Child, Preschool; Conscious Sedation; Extracorporeal Membrane Oxygen

1997
Potency and time course of mivacurium block during sevoflurane, isoflurane and intravenous anesthesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Inhalation; Ane

1999
Awareness during laryngoscopy and intubation: quantitating incidence following induction of balanced anesthesia with etomidate and cisatracurium as detected with the isolated forearm technique.
    Journal of clinical anesthesia, 2000, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intra

2000