isoflurane has been researched along with Nervous System Diseases in 19 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5% isoflurane posttreatment, there was a significant reduction in brain edema, a decrease in apoptotic cell death, and a significant improvement in neurobehavioral deficits." | 7.77 | Isoflurane posttreatment reduces brain injury after an intracerebral hemorrhagic stroke in mice. ( Applegate, R; Fathali, N; Khatibi, NH; Ma, Q; Martin, R; Ostrowski, R; Rolland, W; Stier, G; Tang, J; Zhang, JH, 2011) |
| "24 h prior to intracerebral hemorrhage, C57BL/6J mice were preconditioned with a 4-h exposure to 1% isoflurane gas or room air." | 7.77 | Isoflurane preconditioning affords functional neuroprotection in a murine model of intracerebral hemorrhage. ( Appelboom, G; Connolly, ES; Ducruet, AF; Gigante, PR; Gorski, J; Haque, RM; Hwang, BY; Keesecker, SE; Kellner, CP; Yeh, ML, 2011) |
| "5% isoflurane posttreatment, there was a significant reduction in brain edema, a decrease in apoptotic cell death, and a significant improvement in neurobehavioral deficits." | 3.77 | Isoflurane posttreatment reduces brain injury after an intracerebral hemorrhagic stroke in mice. ( Applegate, R; Fathali, N; Khatibi, NH; Ma, Q; Martin, R; Ostrowski, R; Rolland, W; Stier, G; Tang, J; Zhang, JH, 2011) |
| "24 h prior to intracerebral hemorrhage, C57BL/6J mice were preconditioned with a 4-h exposure to 1% isoflurane gas or room air." | 3.77 | Isoflurane preconditioning affords functional neuroprotection in a murine model of intracerebral hemorrhage. ( Appelboom, G; Connolly, ES; Ducruet, AF; Gigante, PR; Gorski, J; Haque, RM; Hwang, BY; Keesecker, SE; Kellner, CP; Yeh, ML, 2011) |
| "Preconditioning neurons with noninjurious hypoxia (hypoxic preconditioning, HPC) or the anesthetic isoflurane (APC) induces tolerance of severe ischemic stress." | 3.75 | Expression of signal transduction genes differs after hypoxic or isoflurane preconditioning of rat hippocampal slice cultures. ( Bickler, PE; Fahlman, CS, 2009) |
| "Using a rat model of incomplete cerebral ischemia the effects of isoflurane (iso) and methohexital (metho) were compared with those of 70% nitrous oxide controls (N2O)." | 3.68 | Comparison of methohexital and isoflurane on neurologic outcome and histopathology following incomplete ischemia in rats. ( Albrecht, RF; Baughman, VL; Hoffman, WE; Miletich, DJ; Thomas, C, 1990) |
| "Desflurane has demonstrated the indistinguishable blood glucose level and hemodynamic response from isoflurane anesthesia intraoperatively in neurosurgical patients, confirming a comparable pattern of blood glucose concentration intensifying over time spends." | 2.74 | Blood glucose level in neurosurgery. Is it different between isoflurane and desflurane anesthesia? ( Akavipat, P; Pannak, S; Polsayom, N; Punkla, W, 2009) |
| "Isoflurane is a commonly used volatile anesthetic agent for maintenance of general anesthesia in various types of surgery." | 1.51 | Juvenile Rats Show Altered Gut Microbiota After Exposure to Isoflurane as Neonates. ( Wang, L; Wu, H; Yang, X, 2019) |
| "Bupivacaine 3." | 1.37 | Spinal anesthesia in infant rats: development of a model and assessment of neurologic outcomes. ( Athiraman, U; Berde, CB; Carpino, EA; Corfas, G; Soriano, SG; Yahalom, B; Zurakowski, D, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Nie, Y | 1 |
| Li, S | 1 |
| Yan, T | 1 |
| Ma, Y | 1 |
| Ni, C | 1 |
| Wang, H | 1 |
| Zheng, H | 1 |
| Wang, L | 1 |
| Yang, X | 1 |
| Wu, H | 1 |
| Yang, W | 1 |
| Guo, Q | 1 |
| Li, J | 1 |
| Wang, X | 1 |
| Pan, B | 1 |
| Wang, Y | 1 |
| Wu, L | 1 |
| Yan, J | 1 |
| Cheng, Z | 1 |
| Stratmann, G | 2 |
| Sall, JW | 2 |
| May, LD | 2 |
| Loepke, AW | 2 |
| Lee, MT | 2 |
| Serrano, F | 1 |
| Deshazer, M | 1 |
| Smith, KD | 1 |
| Ananta, JS | 1 |
| Wilson, LJ | 1 |
| Pautler, RG | 1 |
| Patel, P | 1 |
| Sun, L | 1 |
| Bickler, PE | 1 |
| Fahlman, CS | 1 |
| Akavipat, P | 1 |
| Polsayom, N | 1 |
| Pannak, S | 1 |
| Punkla, W | 1 |
| Yahalom, B | 1 |
| Athiraman, U | 1 |
| Soriano, SG | 1 |
| Zurakowski, D | 1 |
| Carpino, EA | 1 |
| Corfas, G | 1 |
| Berde, CB | 1 |
| Khatibi, NH | 1 |
| Ma, Q | 1 |
| Rolland, W | 1 |
| Ostrowski, R | 1 |
| Fathali, N | 1 |
| Martin, R | 1 |
| Applegate, R | 1 |
| Stier, G | 1 |
| Tang, J | 1 |
| Zhang, JH | 1 |
| Gigante, PR | 1 |
| Appelboom, G | 1 |
| Hwang, BY | 1 |
| Haque, RM | 1 |
| Yeh, ML | 1 |
| Ducruet, AF | 1 |
| Kellner, CP | 1 |
| Gorski, J | 1 |
| Keesecker, SE | 1 |
| Connolly, ES | 1 |
| Sanders, RD | 1 |
| Ma, D | 1 |
| Maze, M | 1 |
| Zhao, P | 1 |
| Peng, L | 1 |
| Li, L | 1 |
| Xu, X | 1 |
| Zuo, Z | 1 |
| Antognini, JF | 1 |
| Kelsall, AW | 1 |
| Ross-Russell, R | 1 |
| Herrick, MJ | 1 |
| Hoffman, WE | 2 |
| Thomas, C | 2 |
| Albrecht, RF | 2 |
| Baughman, VL | 1 |
| Miletich, DJ | 1 |
| McPherson, RW | 1 |
| Mahla, M | 1 |
| Johnson, R | 1 |
| Traystman, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inhalatorial Sedation in Patient With SAH Versus Conventional Intravenous Sedation (GAS-SAH)[NCT00830843] | Phase 4 | 13 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for isoflurane and Nervous System Diseases
| Article | Year |
|---|---|
Beyond anesthetic properties: the effects of isoflurane on brain cell death, neurogenesis, and long-term neurocognitive function.
Topics: Anesthetics, Inhalation; Animals; Brain; Cell Death; Cognition; Humans; Isoflurane; Nervous System D | 2010 |
Beyond anesthetic properties: the effects of isoflurane on brain cell death, neurogenesis, and long-term neurocognitive function.
Topics: Anesthetics, Inhalation; Animals; Brain; Cell Death; Cognition; Humans; Isoflurane; Nervous System D | 2010 |
Anaesthesia induced neuroprotection.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Humans; Isoflurane; Nervous System Diseases; Neurodege | 2005 |
1 trial available for isoflurane and Nervous System Diseases
| Article | Year |
|---|---|
Blood glucose level in neurosurgery. Is it different between isoflurane and desflurane anesthesia?
Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Glucose; Desflurane; | 2009 |
15 other studies available for isoflurane and Nervous System Diseases
| Article | Year |
|---|---|
Propofol Attenuates Isoflurane-Induced Neurotoxicity and Cognitive Impairment in Fetal and Offspring Mice.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Animals, Newborn; Brain Chemistry; CA1 R | 2020 |
Juvenile Rats Show Altered Gut Microbiota After Exposure to Isoflurane as Neonates.
Topics: Age Factors; Anesthetics, Inhalation; Animals; Animals, Newborn; Gastrointestinal Microbiome; Isoflu | 2019 |
microRNA-124 attenuates isoflurane-induced neurological deficits in neonatal rats via binding to EGR1.
Topics: Animals; Animals, Newborn; Apoptosis; Brain-Derived Neurotrophic Factor; Early Growth Response Prote | 2019 |
Assessing transneuronal dysfunction utilizing manganese-enhanced MRI (MEMRI).
Topics: Animals; Isoflurane; Magnetic Resonance Imaging; Manganese; Memantine; Mice; Mice, Inbred C57BL; Mic | 2008 |
Update on neonatal anesthetic neurotoxicity: insight into molecular mechanisms and relevance to humans.
Topics: Age Factors; Anesthesia; Anesthetics, General; Animals; Apoptosis; Cell Death; Humans; Infant, Newbo | 2009 |
Expression of signal transduction genes differs after hypoxic or isoflurane preconditioning of rat hippocampal slice cultures.
Topics: Anesthetics, Inhalation; Animals; Blotting, Western; Calcium; Calcium Signaling; Cell Death; Glucose | 2009 |
Spinal anesthesia in infant rats: development of a model and assessment of neurologic outcomes.
Topics: Anesthesia, Spinal; Animals; Animals, Newborn; Blood Gas Analysis; Bupivacaine; Disease Models, Anim | 2011 |
Isoflurane posttreatment reduces brain injury after an intracerebral hemorrhagic stroke in mice.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Basal Ganglia; Behavior, Animal; Body Water; Brain; Bra | 2011 |
Isoflurane preconditioning affords functional neuroprotection in a murine model of intracerebral hemorrhage.
Topics: Albumins; Anesthetics, Inhalation; Animals; Brain; Brain Edema; Cerebral Hemorrhage; Disease Models, | 2011 |
Isoflurane preconditioning improves long-term neurologic outcome after hypoxic-ischemic brain injury in neonatal rats.
Topics: Animals; Animals, Newborn; Female; Hypoxia-Ischemia, Brain; Ischemic Preconditioning; Isoflurane; Ma | 2007 |
Neurologic dysfunction after isoflurane sedation.
Topics: Child; Conscious Sedation; Humans; Isoflurane; Nervous System Diseases | 1995 |
Reversible neurologic dysfunction following isoflurane sedation in pediatric intensive care.
Topics: Child; Child, Preschool; Critical Care; Female; Humans; Incidence; Infant; Intubation, Intratracheal | 1994 |
The effect of halothane and isoflurane on neurologic outcome following incomplete cerebral ischemia in the rat.
Topics: Anesthesia, Inhalation; Animals; Brain Ischemia; Catecholamines; Fentanyl; Halothane; Isoflurane; Ma | 1993 |
Comparison of methohexital and isoflurane on neurologic outcome and histopathology following incomplete ischemia in rats.
Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Electroencephalography; Hemodynamics; I | 1990 |
Effects of enflurane, isoflurane, and nitrous oxide on somatosensory evoked potentials during fentanyl anesthesia.
Topics: Anesthesia, General; Arm; Blood Pressure; Body Temperature; Enflurane; Evoked Potentials, Somatosens | 1985 |