isoflurane has been researched along with Myocardial Ischemia in 87 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study compares remifentanil/propofol (remi/prop) with isoflurane/fentanyl (iso/fen) anesthesia to determine which provides the greater hemodynamic stability, lesser myocardial ischemia, and morbidity with better postoperative outcomes after carotid endarterectomy." | 9.10 | Hemodynamic stability, myocardial ischemia, and perioperative outcome after carotid surgery with remifentanil/propofol or isoflurane/fentanyl anesthesia. ( Baker, WH; Jellish, WS; Louie, EK; Sheikh, T; Slogoff, S, 2003) |
| "Sevoflurane is associated with less tachycardia and coronary vasodilation than isoflurane and thus might be associated with less myocardial ischemia." | 9.08 | Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group. ( Ebert, TJ; Kharasch, ED; Muzi, M; Rooke, GA; Shroff, A, 1997) |
| "Early studies indicated that isoflurane caused coronary steal and should therefore be avoided in patients with coronary heart disease." | 8.81 | Isoflurane and coronary heart disease. ( Agnew, NM; Pennefather, SH; Russell, GN, 2002) |
| " Clinical investigations have revealed that isoflurane anesthesia is efficient to alleviate pain during cardiac surgery, including heart bypass surgery." | 7.88 | Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery. ( Lin, H; Pi, Z; Yang, J, 2018) |
| "The results indicate that the volatile anesthetic isoflurane produces a second window of preconditioning against myocardial ischemia and reperfusion injury." | 7.72 | Isoflurane produces delayed preconditioning against myocardial ischemia and reperfusion injury: role of cyclooxygenase-2. ( Alcindor, D; Kersten, JR; Krolikowski, JG; Ludwig, LM; Pagel, PS; Pratt, PF; Tanaka, K; Warltier, DC, 2004) |
| "This study compares remifentanil/propofol (remi/prop) with isoflurane/fentanyl (iso/fen) anesthesia to determine which provides the greater hemodynamic stability, lesser myocardial ischemia, and morbidity with better postoperative outcomes after carotid endarterectomy." | 5.10 | Hemodynamic stability, myocardial ischemia, and perioperative outcome after carotid surgery with remifentanil/propofol or isoflurane/fentanyl anesthesia. ( Baker, WH; Jellish, WS; Louie, EK; Sheikh, T; Slogoff, S, 2003) |
| " Cardiac morbidity (postoperative myocardial ischemia, postoperative myocardial infarction, and perioperative sympathoadrenal stress response), respiratory morbidity (postextubation apnea, alveolar-arterial oxygen gradient, pulmonary shunting, oxygen consumption, atelectasis, and reintubation), hemodynamic values and vasoactive medication requirements, intraoperative awareness, postoperative cognitive function, 30 day mortality, and intensive care unit and hospital lengths of stay were compared between the two groups." | 5.08 | Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial. ( Asokumar, B; Carroll, J; Cheng, DC; David, T; Karski, J; Mickle, D; Nierenberg, H; Peniston, C; Raveendran, G; Roger, S; Sandler, A; Tong, J; Zelovitsky, J, 1996) |
| "Sevoflurane is associated with less tachycardia and coronary vasodilation than isoflurane and thus might be associated with less myocardial ischemia." | 5.08 | Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group. ( Ebert, TJ; Kharasch, ED; Muzi, M; Rooke, GA; Shroff, A, 1997) |
| "Early studies indicated that isoflurane caused coronary steal and should therefore be avoided in patients with coronary heart disease." | 4.81 | Isoflurane and coronary heart disease. ( Agnew, NM; Pennefather, SH; Russell, GN, 2002) |
| " Clinical investigations have revealed that isoflurane anesthesia is efficient to alleviate pain during cardiac surgery, including heart bypass surgery." | 3.88 | Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery. ( Lin, H; Pi, Z; Yang, J, 2018) |
| "The rat models were established and divided in acute myocardial ischemia model (myocardial ischemia 30 min, 1 h, 2 h groups), ischemia-reperfusion model (ischemia-reperfusion group), and isoflurane-pretreated ischemia-reperfusion model (isoflurane-pretreated group), respectively." | 3.80 | [Cathepsin L expression in plasma after acute myocardial ischemia and ischemia-reperfusion in rats]. ( Liang, Z; Yan, P; Zhang, GQ; Zhang, XJ, 2014) |
| "The results indicate that the volatile anesthetic isoflurane produces a second window of preconditioning against myocardial ischemia and reperfusion injury." | 3.72 | Isoflurane produces delayed preconditioning against myocardial ischemia and reperfusion injury: role of cyclooxygenase-2. ( Alcindor, D; Kersten, JR; Krolikowski, JG; Ludwig, LM; Pagel, PS; Pratt, PF; Tanaka, K; Warltier, DC, 2004) |
| "Isoflurane applied before myocardial ischemia has a beneficial preconditioning effect which involves generation of reactive oxygen species (ROS); ROS, however, have been implicated in critical cytosolic calcium ([Ca2+]i) overload during ischemia." | 3.72 | Isoflurane applied during ischemia enhances intracellular calcium accumulation in ventricular myocytes in part by reactive oxygen species. ( Breukelmann, D; Dworschak, M; Hannon, JD, 2004) |
| "Our results shows that blockade of the KATP channel abolishes cardioprotective effects of isoflurane in myocardial ischemia-reperfusion." | 3.69 | Blockade of ATP-sensitive K+ channel abolishes the anti-ischemic effects of isoflurane in dog hearts. ( Fujita, S; Kanaya, N; Nakayama, M; Namiki, A; Tsuchida, H, 1997) |
| "We evaluated the risk of myocardial ischemia under isoflurane anesthesia (vs." | 3.68 | Effects of steal-prone anatomy on intraoperative myocardial ischemia. The SPI Research Group. ( Hollenberg, M; Kao, A; Leung, JM; Mangano, DT; O'Kelly, BF, 1992) |
| "Eighty children scheduled for ventricular septal defect closure under cardioplegic arrest were assigned to preconditioning for five minutes after commencement of cardiopulmonary bypass (CPB) with one minimum alveolar concentration (MAC) of one of the following agents: isoflurane, sevoflurane, desflurane, or placebo (oxygen-air mixture)." | 2.78 | Comparison of cardioprotective effects of volatile anesthetics in children undergoing ventricular septal defect closure. ( Chauhan, S; Jain, G; Kiran, U; Makhija, N; Singh, P; Talwar, S, 2013) |
| "Isoflurane (0." | 1.48 | The Effect of Mitochondrial Complex I-Linked Respiration by Isoflurane Is Independent of Mitochondrial Nitric Oxide Production. ( An, J; Deng, Y; Li, H; Qiao, S; Wang, C; Xu, F, 2018) |
| "Isoflurane was introduced for general clinical use in North America in 1981." | 1.46 | Isoflurane and the Coronary Steal Controversy of the 1980s: Origin, Resolution, and Legacy. ( Crystal, GJ, 2017) |
| "We sought to determine whether brain death-induced catecholamine release preconditions the heart, and if not, whether it precludes further protection by repetitive ischemia or isoflurane." | 1.31 | Preservation of ischemia and isoflurane-induced preconditioning after brain death in rabbit hearts. ( Chiari, P; Ferrera, R; Hadour, G; Lehot, JJ; Loufouat, J; Ovize, M; Piriou, V; Rodriguez, C, 2002) |
| "Sevoflurane has been reported to generate oxygen free radicals." | 1.30 | Effects of sevoflurane and isoflurane on free radical formation in the post-ischaemic reperfused heart. ( Ikeya, K; Kashimoto, S; Kumazawa, T; Kume, M, 1998) |
| "Hydroxyl radicals were identified by their reaction with salicylic acid to yield dihydroxybenzoic acids (DHBAs)." | 1.30 | Hydroxyl radical formation during inhalation anesthesia in the reperfused working rat heart. ( Kashimoto, S; Kumazawa, T; Nakamura, T; Oguchi, T, 1999) |
| "Myocardial ischemia was associated with significant (P < 0." | 1.29 | Post-ischemic diastolic dysfunction. ( Dalmas, S; Foëx, P; Marsch, SC; Philbin, DM; Ryder, WA; Wanigasekera, VA; Wong, LS, 1994) |
| "When isoflurane was discontinued both the ECG and the cardiovascular changes returned to the previous condition." | 1.29 | Repeated episodes of myocardial ischaemia during combined thoracic epidural-isoflurane anaesthesia. ( Brouwer, RP; Sigurdsson, GH; Thomson, D, 1994) |
| "Isoflurane was discontinued at the onset of the final reperfusion period." | 1.29 | Mechanism of myocardial protection by isoflurane. Role of adenosine triphosphate-regulated potassium (KATP) channels. ( Gross, GJ; Hettrick, DA; Kersten, JR; Pagel, PS; Schmeling, TJ; Warltier, DC, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.30) | 18.7374 |
| 1990's | 49 (56.32) | 18.2507 |
| 2000's | 25 (28.74) | 29.6817 |
| 2010's | 10 (11.49) | 24.3611 |
| 2020's | 1 (1.15) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, H | 1 |
| Qing, X | 1 |
| Li, H | 2 |
| Crystal, GJ | 1 |
| Pi, Z | 1 |
| Lin, H | 1 |
| Yang, J | 1 |
| Xu, F | 1 |
| Qiao, S | 1 |
| Deng, Y | 1 |
| Wang, C | 2 |
| An, J | 1 |
| Warltier, DC | 8 |
| Singh, P | 1 |
| Chauhan, S | 1 |
| Jain, G | 1 |
| Talwar, S | 1 |
| Makhija, N | 1 |
| Kiran, U | 1 |
| Mellidis, K | 1 |
| Ordodi, V | 1 |
| Galatou, E | 1 |
| Săndesc, D | 1 |
| Bubenek, S | 1 |
| Duicu, O | 1 |
| Muntean, D | 2 |
| Lazou, A | 1 |
| Zhang, GQ | 1 |
| Liang, Z | 1 |
| Yan, P | 1 |
| Zhang, XJ | 1 |
| Baotic, I | 1 |
| Weihrauch, D | 2 |
| Procknow, J | 1 |
| Vasquez-Vivar, J | 1 |
| Ge, ZD | 1 |
| Sudhakaran, S | 1 |
| Kersten, JR | 6 |
| Onk, D | 1 |
| Akarsu Ayazoğlu, T | 1 |
| Onk, OA | 1 |
| Aksüt, M | 1 |
| Günay, M | 1 |
| Turkmen, K | 1 |
| Özensoy, A | 1 |
| Yazıcı Ersoy, Ç | 1 |
| Çoban, A | 1 |
| Hu, ZY | 1 |
| Liu, J | 2 |
| Liu, L | 1 |
| Ran, K | 1 |
| Chang, Y | 1 |
| Chiari, P | 2 |
| Piriou, V | 3 |
| Hadour, G | 1 |
| Rodriguez, C | 1 |
| Loufouat, J | 2 |
| Lehot, JJ | 2 |
| Ovize, M | 2 |
| Ferrera, R | 1 |
| Teo, A | 1 |
| Koh, KF | 1 |
| Jellish, WS | 1 |
| Sheikh, T | 1 |
| Baker, WH | 1 |
| Louie, EK | 1 |
| Slogoff, S | 1 |
| Tanaka, K | 2 |
| Ludwig, LM | 1 |
| Krolikowski, JG | 3 |
| Alcindor, D | 1 |
| Pratt, PF | 1 |
| Pagel, PS | 6 |
| Gateau-Roesch, O | 1 |
| Argaud, L | 1 |
| Salles, D | 1 |
| Gueugniaud, PY | 1 |
| Kendall, JB | 1 |
| Russell, GN | 2 |
| Scawn, ND | 1 |
| Akrofi, M | 1 |
| Cowan, CM | 1 |
| Fox, MA | 1 |
| Dworschak, M | 1 |
| Breukelmann, D | 1 |
| Hannon, JD | 1 |
| Xu, P | 1 |
| Wang, J | 3 |
| Kodavatiganti, R | 1 |
| Zeng, Y | 1 |
| Kass, IS | 1 |
| Qian, LP | 1 |
| Zhu, SS | 1 |
| Cao, JL | 1 |
| Zeng, YM | 1 |
| Neff, DA | 1 |
| Bienengraeber, M | 1 |
| Ruzsics, B | 1 |
| Surányi, P | 1 |
| Kiss, P | 1 |
| Brott, BC | 1 |
| Elgavish, A | 1 |
| Saab-Ismail, NH | 1 |
| Simor, T | 1 |
| Elgavish, GA | 1 |
| Neuhäuser, C | 1 |
| Müller, M | 1 |
| Welters, I | 1 |
| Scholz, S | 1 |
| Kwapisz, MM | 1 |
| Yu, CH | 1 |
| Beattie, WS | 1 |
| Ralley, FE | 1 |
| Merin, RG | 1 |
| Patel, HH | 1 |
| Tsutsumi, YM | 1 |
| Head, BP | 1 |
| Niesman, IR | 1 |
| Jennings, M | 1 |
| Horikawa, Y | 1 |
| Huang, D | 1 |
| Moreno, AL | 1 |
| Patel, PM | 1 |
| Insel, PA | 1 |
| Roth, DM | 1 |
| Lange, M | 2 |
| Roewer, N | 2 |
| Kehl, F | 3 |
| Redel, A | 1 |
| Jazbutyte, V | 1 |
| Lotz, C | 1 |
| Smul, TM | 1 |
| Landoni, G | 1 |
| Fochi, O | 1 |
| Zangrillo, A | 1 |
| Lucchinetti, E | 1 |
| Schaub, MC | 1 |
| Zaugg, M | 1 |
| Rao, Y | 1 |
| Wang, YL | 1 |
| Zhang, WS | 1 |
| Hettrick, DA | 2 |
| Lowe, D | 1 |
| Tessmer, JP | 1 |
| Archer, DP | 1 |
| Tang, TK | 1 |
| Mutch, WA | 1 |
| White, IW | 1 |
| Donen, N | 1 |
| Thomson, IR | 1 |
| Rosenbloom, M | 1 |
| Cheang, M | 1 |
| West, M | 1 |
| Cason, BA | 1 |
| Gordon, HJ | 1 |
| Avery, EG | 1 |
| Hickey, RF | 1 |
| Domenegati, E | 1 |
| Maurelli, M | 1 |
| Chiaudani, MG | 1 |
| Pagnin, A | 1 |
| Rinaldi, M | 1 |
| Louvier, N | 1 |
| Lançon, JP | 1 |
| Kanaya, N | 2 |
| Kobayashi, I | 1 |
| Nakayama, M | 2 |
| Fujita, S | 3 |
| Namiki, A | 2 |
| Oguchi, T | 3 |
| Kashimoto, S | 4 |
| Yamaguchi, T | 2 |
| Nakamura, T | 3 |
| Kumazawa, T | 4 |
| Sahlman, L | 1 |
| Waagstein, L | 1 |
| Haljamäe, H | 1 |
| Ricksten, SE | 1 |
| Wouters, PF | 1 |
| Van Aken, H | 2 |
| Van de Velde, M | 1 |
| Marcus, MA | 1 |
| Flameng, W | 2 |
| Marsch, SC | 1 |
| Dalmas, S | 1 |
| Philbin, DM | 1 |
| Wanigasekera, VA | 1 |
| Ryder, WA | 1 |
| Wong, LS | 1 |
| Foëx, P | 2 |
| Hohner, P | 2 |
| Nancarrow, C | 1 |
| Backman, C | 2 |
| Häggmark, S | 2 |
| Johansson, G | 2 |
| Fridén, H | 1 |
| Diamond, G | 2 |
| Friedman, A | 2 |
| Reiz, S | 2 |
| Karp, K | 1 |
| Sigurdsson, GH | 1 |
| Brouwer, RP | 1 |
| Thomson, D | 1 |
| Reitan, JA | 1 |
| Kien, ND | 1 |
| Moore, PG | 1 |
| White, DA | 1 |
| Haessler, R | 1 |
| Kuzume, K | 1 |
| Chien, GL | 1 |
| Wolff, RA | 1 |
| Davis, RF | 1 |
| Van Winkle, DM | 1 |
| Hogue, CW | 1 |
| Pulley, DD | 1 |
| Lappas, DG | 1 |
| Spahn, DR | 1 |
| Hu, WC | 1 |
| Smith, LR | 1 |
| Leone, BJ | 1 |
| Veit, S | 1 |
| Müser, HG | 1 |
| Böttcher, E | 1 |
| Brückner, JB | 1 |
| Nathan, HJ | 1 |
| Smallman, B | 1 |
| Diana, P | 1 |
| Tullock, WC | 1 |
| Gorcsan, J | 1 |
| Ferson, PF | 1 |
| Arvan, S | 1 |
| Mattheussen, M | 1 |
| Rusy, BF | 1 |
| Biddle, C | 1 |
| Turner, LA | 2 |
| Polic, S | 2 |
| Hoffmann, RG | 2 |
| Kampine, JP | 2 |
| Bosnjak, ZJ | 4 |
| Daniel, M | 1 |
| Eger, EI | 1 |
| Weiskopf, RB | 1 |
| Noorani, M | 1 |
| Chan, VW | 1 |
| Chung, FF | 1 |
| Cheng, DC | 2 |
| Karski, J | 1 |
| Peniston, C | 1 |
| Asokumar, B | 2 |
| Raveendran, G | 1 |
| Carroll, J | 1 |
| Nierenberg, H | 1 |
| Roger, S | 1 |
| Mickle, D | 1 |
| Tong, J | 1 |
| Zelovitsky, J | 1 |
| David, T | 1 |
| Sandler, A | 2 |
| Jiang, MT | 1 |
| Boylen, P | 1 |
| Botero, C | 1 |
| Smith, CE | 1 |
| Morscher, AH | 1 |
| Schmeling, TJ | 2 |
| Gross, GJ | 3 |
| Searle, NR | 1 |
| Martineau, RJ | 1 |
| Conzen, P | 1 |
| al-Hasani, A | 1 |
| Mark, L | 1 |
| Ebert, T | 1 |
| Muzi, M | 2 |
| Hodgins, LR | 1 |
| Boutros, A | 1 |
| Capuano, C | 1 |
| Tsuchida, H | 1 |
| Ross, S | 1 |
| Pigott, D | 1 |
| Evans, R | 1 |
| Ebert, TJ | 1 |
| Kharasch, ED | 1 |
| Rooke, GA | 1 |
| Shroff, A | 1 |
| Mathur, S | 1 |
| Karmazyn, M | 1 |
| Stowe, DF | 1 |
| Kume, M | 1 |
| Ikeya, K | 1 |
| Murray, JM | 1 |
| Luney, SR | 1 |
| Hochhauser, E | 1 |
| Halpern, P | 1 |
| Zolotarsky, V | 1 |
| Krasnov, T | 1 |
| Sulkes, J | 1 |
| Vidne, B | 1 |
| Wasnick, JD | 1 |
| Haile, KK | 1 |
| Acuff, T | 1 |
| Moir, CL | 1 |
| Rieke, H | 1 |
| Kazmaier, S | 1 |
| Lange, H | 1 |
| Weyland, A | 1 |
| Sonntag, H | 1 |
| Heindl, B | 1 |
| Becker, BF | 1 |
| Takuma, S | 1 |
| Suehiro, K | 1 |
| Cardinale, C | 1 |
| Hozumi, T | 1 |
| Yano, H | 1 |
| Shimizu, J | 1 |
| Mullis-Jansson, S | 1 |
| Sciacca, R | 1 |
| Burkhoff, D | 1 |
| Di Tullio, MR | 1 |
| Homma, S | 1 |
| Agnew, NM | 1 |
| Pennefather, SH | 1 |
| Gu, W | 1 |
| Tonkovic-Capin, M | 1 |
| Tweddell, JS | 1 |
| Fitzpatrick, CM | 1 |
| Baker, JE | 1 |
| Leung, JM | 1 |
| Hollenberg, M | 1 |
| O'Kelly, BF | 1 |
| Kao, A | 1 |
| Mangano, DT | 1 |
| Stühmeier, KD | 1 |
| Mainzer, B | 1 |
| Sandmann, W | 1 |
| Tarnow, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sevoflurane and Cardiac Protection in High Risk Patients Undergoing Cardiac Surgery. A Randomized Controlled Study.[NCT00821262] | Phase 4 | 200 participants (Actual) | Interventional | 2008-09-30 | Completed | ||
| Effects on Bleeding in Knee Arthroplasty After Ischemic Preconditioning With Sevoflurane[NCT03379103] | 30 participants (Actual) | Interventional | 2018-02-02 | Completed | |||
| [NCT00005197] | 0 participants | Observational | 1986-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for isoflurane and Myocardial Ischemia
| Article | Year |
|---|---|
The effects of volatile anesthetics on cardiac ischemic complications and mortality in CABG: a meta-analysis.
Topics: Anesthetics, Inhalation; Coronary Artery Bypass; Creatine Kinase, MB Form; Desflurane; Electrocardio | 2006 |
The role of ATP sensitive potassium channels in myocardial protection.
Topics: Adenosine Triphosphate; Animals; Barbiturates; Halothane; Humans; Isoflurane; Myocardial Ischemia; P | 1995 |
[Do halogenated anesthetics protect from ischemic and reperfusion myocardial injuries?].
Topics: Animals; Calcium Channels; Cats; Dogs; Enflurane; Free Radicals; Halothane; Heart; Isoflurane; Myoca | 1994 |
Anesthetic-induced myocardial ischemia: the isoflurane-coronary steal controversy.
Topics: Animals; Cardiovascular Surgical Procedures; Coronary Circulation; Humans; Isoflurane; Myocardial Is | 1993 |
Isoflurane and coronary heart disease.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Cardiotonic Agents; Coronary Disease; Humans; Ische | 2002 |
16 trials available for isoflurane and Myocardial Ischemia
| Article | Year |
|---|---|
Comparison of cardioprotective effects of volatile anesthetics in children undergoing ventricular septal defect closure.
Topics: Anesthetics, Inhalation; Cardiopulmonary Bypass; Cardiotonic Agents; Creatine Kinase, MB Form; Desfl | 2013 |
Comparison of TIVA and Desflurane Added to a Subanaesthetic Dose of Propofol in Patients Undergoing Coronary Artery Bypass Surgery: Evaluation of Haemodynamic and Stress Hormone Changes.
Topics: Aged; Aged, 80 and over; Anesthesia, Intravenous; Anesthetics, Inhalation; Aorta; Biomarkers; Body M | 2016 |
Hemodynamic stability, myocardial ischemia, and perioperative outcome after carotid surgery with remifentanil/propofol or isoflurane/fentanyl anesthesia.
Topics: Aged; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Carotid Artery Disea | 2003 |
A prospective, randomised, single-blind pilot study to determine the effect of anaesthetic technique on troponin T release after off-pump coronary artery surgery.
Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2004 |
Effect of isoflurane on echocardiographic left-ventricular relaxation indices in patients with diastolic dysfunction due to concentric hypertrophy and ischemic heart disease.
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Antihypertensive Agents; Cardiovascular Phy | 2006 |
Haemodynamic instability and myocardial ischaemia during carotid endarterectomy: a comparison of propofol and isoflurane.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave | 1995 |
Anaesthesia for abdominal vascular surgery in patients with coronary artery disease (CAD), Part I: Isoflurane produces dose-dependent coronary vasodilation.
Topics: Abdomen; Aged; Aged, 80 and over; Anesthesia; Coronary Circulation; Coronary Disease; Dose-Response | 1994 |
Anaesthesia for abdominal aortic surgery in patients with coronary artery disease, Part II: Effects of nitrous oxide on systemic and coronary haemodynamics, regional ventricular function and incidence of myocardial ischaemia.
Topics: Abdomen; Anesthesia; Coronary Circulation; Coronary Disease; Female; Fentanyl; Hemodynamics; Humans; | 1994 |
Myocardial ischemia: a comparison between isoflurane and enflurane in coronary artery bypass patients.
Topics: Aged; Anesthesia, Inhalation; Coronary Artery Bypass; Enflurane; Female; Humans; Isoflurane; Male; M | 1993 |
Propofol fails to attenuate the cardiovascular response to rapid increases in desflurane concentration.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Desflurane; Dose-Response Rela | 1996 |
Propofol infusion for induction and maintenance of anesthesia in elderly patients: recovery and hemodynamic profiles.
Topics: Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Int | 1996 |
Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial.
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Apnea; Catecholamines; | 1996 |
Comparison of sevoflurane/fentanyl and isoflurane/fentanyl during elective coronary artery bypass surgery. Sevoflurane Venture Group.
Topics: Aged; Anesthetics, Inhalation; Coronary Artery Bypass; Electrocardiography, Ambulatory; Ethers; Fema | 1996 |
Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Coronary Disease; Ethers; Female; Heart Dis | 1997 |
[Does method of anesthesia modify postoperative ischemia incidence? A study of patients after aortocoronary bypass operations].
Topics: Adult; Aged; Anesthesia, General; Coronary Artery Bypass; Electrocardiography; Enflurane; Fentanyl; | 1999 |
Isoflurane does not increase the incidence of intraoperative myocardial ischaemia compared with halothane during vascular surgery.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Female; Halothane; Hemodynamics; Humans; In | 1992 |
66 other studies available for isoflurane and Myocardial Ischemia
| Article | Year |
|---|---|
Isoflurane Preconditioning Protects the Myocardium Against Ischemia and Reperfusion Injury by Upregulating GRM1 Expression.
Topics: Anesthetics, Inhalation; Animals; Ischemic Preconditioning; Isoflurane; Mice; Myocardial Ischemia; M | 2020 |
Isoflurane and the Coronary Steal Controversy of the 1980s: Origin, Resolution, and Legacy.
Topics: Anesthetics, Inhalation; Coronary Circulation; History, 20th Century; Humans; Isoflurane; Myocardial | 2017 |
Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery.
Topics: Animals; Apoptosis; Coronary Artery Bypass; Isoflurane; Male; Mice; Myocardial Ischemia; Myocardium; | 2018 |
The Effect of Mitochondrial Complex I-Linked Respiration by Isoflurane Is Independent of Mitochondrial Nitric Oxide Production.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Isof | 2018 |
Classic Papers Revisited: An Early Study of Cardioprotection by Volatile Anesthetics: A Behind-the-scenes Look.
Topics: Anesthetics, Inhalation; Animals; Cardiotonic Agents; Dogs; Halothane; Humans; Isoflurane; Myocardia | 2018 |
Activation of prosurvival signaling pathways during the memory phase of volatile anesthetic preconditioning in human myocardium: a pilot study.
Topics: Aged; Anesthetics, General; Anesthetics, Inhalation; Extracellular Signal-Regulated MAP Kinases; Fem | 2014 |
[Cathepsin L expression in plasma after acute myocardial ischemia and ischemia-reperfusion in rats].
Topics: Animals; Biomarkers; Cathepsin L; Isoflurane; Myocardial Infarction; Myocardial Ischemia; Myocardial | 2014 |
Isoflurane favorably modulates guanosine triphosphate cyclohydrolase-1 and endothelial nitric oxide synthase during myocardial ischemia and reperfusion injury in rats.
Topics: Anesthetics, Inhalation; Animals; GTP Cyclohydrolase; Isoflurane; Male; Myocardial Ischemia; Myocard | 2015 |
Effects of emulsified isoflurane on haemodynamics and cardiomyocyte apoptosis in rats with myocardial ischaemia.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Cardiotonic Agents; Caspase 3; Disea | 2009 |
[Effect of isoflurane delayed preconditioning on the expression of Bcl-2 and caspase-3 in myocardium during ischemia reperfusion in rabbits].
Topics: Animals; Apoptosis; Caspase 3; Gene Expression Regulation; Ischemic Preconditioning, Myocardial; Iso | 2010 |
Preservation of ischemia and isoflurane-induced preconditioning after brain death in rabbit hearts.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Brain Death; Catecholamines; Female; Heart Rate; I | 2002 |
Isoflurane and coronary steal.
Topics: Anesthetics, Inhalation; Coronary Artery Bypass; Coronary Disease; Humans; Intraoperative Complicati | 2003 |
Isoflurane produces delayed preconditioning against myocardial ischemia and reperfusion injury: role of cyclooxygenase-2.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Blotting, Western; Celecoxib; Coronary Circulation | 2004 |
Desflurane-induced preconditioning alters calcium-induced mitochondrial permeability transition.
Topics: Anesthetics, Inhalation; Animals; Calcium; Cyclosporine; Decanoic Acids; Desflurane; Hemodynamics; H | 2004 |
Isoflurane applied during ischemia enhances intracellular calcium accumulation in ventricular myocytes in part by reactive oxygen species.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Calcium; Disease Models, Animal; Fluorescent | 2004 |
Activation of protein kinase C contributes to the isoflurane-induced improvement of functional and metabolic recovery in isolated ischemic rat hearts.
Topics: Adenosine Triphosphate; Alkaloids; Anesthetics, Inhalation; Animals; Benzophenanthridines; Energy Me | 2004 |
Isoflurane preconditioning protects against ischemia-reperfusion injury partly by attenuating cytochrome c release from subsarcolemmal mitochondria in isolated rat hearts.
Topics: Animals; Cytochromes c; Dose-Response Relationship, Drug; Heart Rate; In Vitro Techniques; Ischemic | 2005 |
The influence of B-cell lymphoma 2 protein, an antiapoptotic regulator of mitochondrial permeability transition, on isoflurane-induced and ischemic postconditioning in rabbits.
Topics: Animals; Apoptosis; Intracellular Membranes; Ion Channels; Ischemic Preconditioning, Myocardial; Iso | 2006 |
Gd(ABE-DTTA), a novel contrast agent, at the MRI-effective dose shows absence of deleterious physiological effects in dogs.
Topics: Alanine Transaminase; Amylases; Anesthetics, Inhalation; Animals; Blood Proteins; Contrast Media; Do | 2006 |
Pro: Isoflurane is contraindicated for use in coronary artery surgery.
Topics: Anesthetics, Inhalation; Animals; Contraindications; Coronary Artery Disease; Coronary Vessels; Dogs | 1988 |
Con: Isoflurane is contraindicated in patients with coronary artery disease.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Contraindications; Coronary Artery Disease; Corona | 1988 |
Mechanisms of cardiac protection from ischemia/reperfusion injury: a role for caveolae and caveolin-1.
Topics: Animals; Base Sequence; Caveolin 1; DNA Primers; Isoflurane; Male; Mice; Mice, Inbred C57BL; Mice, K | 2007 |
Beta-blockers and anesthetic preconditioning: friend or foe?
Topics: Adrenergic beta-Antagonists; Anesthetics, Inhalation; Coronary Artery Bypass; Desflurane; Heart; Hum | 2007 |
Activation of mitochondrial large-conductance calcium-activated K+ channels via protein kinase A mediates desflurane-induced preconditioning.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Desflurane; Ischemic Preconditioning, Myocardial; Iso | 2008 |
Cardioprotection by volatile anesthetics in noncardiac surgery? No, not yet at least.
Topics: Anesthetics, Inhalation; Cardiotonic Agents; Enflurane; Evidence-Based Medicine; Halothane; Humans; | 2008 |
Emulsified intravenous versus evaporated inhaled isoflurane for heart protection: old wine in a new bottle or true innovation?
Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Chemistry, Pharmaceutical; Coronary Ve | 2008 |
Emulsified isoflurane produces cardiac protection after ischemia-reperfusion injury in rabbits.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Coronary Vessels; Creatine Kinase; Cyt | 2008 |
Desflurane and isoflurane exert modest beneficial actions on left ventricular diastolic function during myocardial ischemia in dogs.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Coronary Circulation; Desflurane; Dogs; He | 1995 |
The choice of anaesthetic for carotid endarterectomy: does it matter?
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 1995 |
Management of anesthesia during dynamic cardiomyoplasty.
Topics: Adult; Cardiomyopathy, Dilated; Cardiomyoplasty; Electric Stimulation Therapy; Humans; Isoflurane; M | 1995 |
ATP sparing effect of isoflurane during ischaemia and reperfusion of the canine heart.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiac Output; Dogs; Female; Isoflurane; Lactates; | 1995 |
Comparative effects of halothane, enflurane, isoflurane and sevoflurane on function and metabolism in the ischaemic rat heart.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Cardiac Output; Coronary Circulation; Enfl | 1995 |
Protective effects of halothane but not isoflurane against global ischaemic injury in the isolated working rat heart.
Topics: Animals; Halothane; Heart; In Vitro Techniques; Isoflurane; Lactates; Lactic Acid; Myocardial Contra | 1995 |
Functional adaptation to myocardial ischemia: interaction with volatile anesthetics in chronically instrumented dogs.
Topics: Adaptation, Physiological; Animals; Dogs; Female; Heart; Isoflurane; Male; Myocardial Ischemia; Myoc | 1994 |
Post-ischemic diastolic dysfunction.
Topics: Anesthesia, Inhalation; Animals; Cardiac Output; Cardiac Volume; Diastole; Dogs; Elasticity; Heart V | 1994 |
Repeated episodes of myocardial ischaemia during combined thoracic epidural-isoflurane anaesthesia.
Topics: Anesthesia, Epidural; Anesthesia, Inhalation; Aortic Aneurysm, Abdominal; Blood Pressure; Cardiac Ou | 1994 |
Regional myocardial function during contiguous ischaemia in an anaesthetized canine model: comparison of six methods of measurement.
Topics: Animals; Disease Models, Animal; Dogs; Dopamine; Epinephrine; Female; Halothane; Heart; Heart Functi | 1994 |
Anaesthetics alter the magnitude of infarct limitation by ischaemic preconditioning.
Topics: Anesthetics; Animals; Blood Glucose; Constriction; Coronary Vessels; Heart; Isoflurane; Ketamine; My | 1994 |
Pacing-induced left ventricular asynchronies in dogs with critical coronary stenosis: mechanisms and effect of anesthetics.
Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Cardiac Pacing, Artifici | 1993 |
[Signs of a severe myocardial ischemia following peritonsillar infiltration with ornipressin (POR 8)].
Topics: Adult; Anesthesia, Inhalation; Humans; Isoflurane; Male; Myocardial Ischemia; Nitrous Oxide; Ornipre | 1993 |
Isoflurane, compared to halothane or enflurane, causes increased lactate production but no transmural coronary steal during myocardial ischemia in swine.
Topics: Animals; Coronary Vessels; Enflurane; Halothane; Isoflurane; Lactates; Myocardial Ischemia; Stimulat | 1993 |
Recovery of function and adenosine triphosphate metabolism following myocardial ischemia induced in the presence of volatile anesthetics.
Topics: Adenosine Triphosphate; Animals; Halothane; Heart; Hemodynamics; Isoflurane; Myocardial Ischemia; My | 1993 |
Risk of ischemia in patients receiving desflurane versus sufentanil: sample size and clinical significance.
Topics: Anesthetics; Coronary Artery Bypass; Desflurane; Humans; Isoflurane; Myocardial Ischemia; Risk; Sufe | 1993 |
Actions of halothane and isoflurane on Purkinje fibers in the infarcted canine heart: conduction, regional refractoriness, and reentry.
Topics: Animals; Disease Models, Animal; Dogs; Electric Stimulation; Electrophysiology; Halothane; Heart Con | 1993 |
Actions of volatile anesthetics on ischemic and nonischemic Purkinje fibers in the canine heart: regional action potential characteristics.
Topics: Action Potentials; Anesthetics; Animals; Dogs; Enflurane; Halothane; Isoflurane; Myocardial Infarcti | 1993 |
Is pentobarbital appropriate for basal anesthesia in the working rat heart model?
Topics: Administration, Inhalation; Anesthesia; Animals; Ethers; Heart; Hemodynamics; Injections, Intraperit | 1993 |
Comparison of nifedipine and metoprolol on collateral coronary blood flow in a swine model of chronic coronary obstruction and acute ischaemia during isoflurane anaesthesia.
Topics: Adrenergic beta-Antagonists; Anesthetics, Inhalation; Animals; Calcium Channel Blockers; Chronic Dis | 1996 |
Anemia and perioperative myocardial ischemia in a Jehovah's Witness patient.
Topics: Adrenergic beta-Antagonists; Anemia; Anesthetics, Inhalation; Cholinesterase Inhibitors; Christianit | 1996 |
Mechanism of myocardial protection by isoflurane. Role of adenosine triphosphate-regulated potassium (KATP) channels.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Coronary Circulation; Dogs; Drug Interacti | 1996 |
Isoflurane and halothane increase adenosine triphosphate preservation, but do not provide additive recovery of function after ischemia, in preconditioned rat hearts.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Halothane; Hemodynamics; Isoflurane; Male; Myocardi | 1997 |
Blockade of ATP-sensitive K+ channel abolishes the anti-ischemic effects of isoflurane in dog hearts.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Dogs; Female; Glyburide; Isoflurane; Male; | 1997 |
Isoflurane mimics ischemic preconditioning via activation of K(ATP) channels: reduction of myocardial infarct size with an acute memory phase.
Topics: Anesthetics, Inhalation; Animals; Coronary Circulation; Dogs; Glyburide; Hemodynamics; Hypoglycemic | 1997 |
Beneficial effect of concomitant administration of isoflurane and nicorandil.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Drug Therapy, Co | 1997 |
Interaction between anesthetics and the sodium-hydrogen exchange inhibitor HOE 642 (cariporide) in ischemic and reperfused rat hearts.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Drug Interactions; Ethers; Guanidines; H | 1997 |
Improved contractility and coronary flow in isolated hearts after 1-day hypothermic preservation with isoflurane is not dependent on K(ATP) channel activation.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Cold Temperature; Coronary Circulation; Gu | 1998 |
Effects of sevoflurane and isoflurane on free radical formation in the post-ischaemic reperfused heart.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Cardiac Output; Chromatography, High Pressure Liqu | 1998 |
Fatal cardiac ischaemia associated with prolonged desflurane anaesthesia and administration of exogenous catecholamines.
Topics: Aged; Anesthetics, Inhalation; Blood Pressure; Bradycardia; Cardiotonic Agents; Coronary Disease; Cr | 1998 |
Isoflurane and sodium nitroprusside reduce the depressant effects of protamine sulfate on isolated ischemic rat hearts.
Topics: Anesthetics, Inhalation; Animals; Drug Interactions; Heart Arrest, Induced; Hemodynamics; Heparin An | 1999 |
Anesthetic management of minimally invasive laser transmyocardial revascularization.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Angina Pectoris; Desflurane; | 1999 |
Hydroxyl radical formation during inhalation anesthesia in the reperfused working rat heart.
Topics: Anesthetics, Inhalation; Animals; Halothane; Hydroxyl Radical; Isoflurane; Male; Methyl Ethers; Myoc | 1999 |
Cardiac ischemia and desflurane.
Topics: Adrenergic Agents; Anesthesia, Inhalation; Anesthetics, Inhalation; Cardiotonic Agents; Desflurane; | 1999 |
Sevoflurane and isoflurane do not enhance the pre- and postischemic eicosanoid production in guinea pig hearts.
Topics: Anesthetics, Inhalation; Animals; Coronary Circulation; Dinoprost; Eicosanoids; Guinea Pigs; Hemodyn | 2000 |
Anesthetic inhibition in ischemic and nonischemic murine heart: comparison with conscious echocardiographic approach.
Topics: Anesthetics, Inhalation; Animals; Consciousness; Echocardiography; Heart Rate; Isoflurane; Mice; Myo | 2001 |
Isoflurane-induced preconditioning is attenuated by diabetes.
Topics: Anesthetics, Inhalation; Animals; Blood Glucose; Constriction; Coronary Vessels; Diabetes Mellitus, | 2002 |
Delayed cardioprotection by isoflurane: role of K(ATP) channels.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Benzamides; Cytoprotection; Decanoic Acids; Dose- | 2002 |
Effects of steal-prone anatomy on intraoperative myocardial ischemia. The SPI Research Group.
Topics: Adult; Aged; Analysis of Variance; Chi-Square Distribution; Collateral Circulation; Coronary Circula | 1992 |