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isoflurane and Myasthenia Gravis

isoflurane has been researched along with Myasthenia Gravis in 8 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

Research Excerpts

ExcerptRelevanceReference
"We describe the use of isoflurane for the management of a 3-yr-old boy with congenital myasthenia gravis who required ventilation for pneumonia."7.69Isoflurane for sedation in a case of congenital myasthenia gravis. ( McBeth, C; Watkins, TG, 1996)
" In the first, isoflurane alone is administered, and mivacurium with isoflurane is administered to the second patient with myasthenia gravis."7.68Isoflurane and mivacurium chloride neuromuscular blockade in patients with myasthenia gravis. ( Mangar, D; Stillwell, R; Turnage, WS, 1993)
"We studied neuromuscular blocking effects of isoflurane using a neuromuscular transmission monitor in three myasthenia gravis patients."7.68[Severity of myasthenia gravis is related to the degree of neuromuscular blocking effect by isoflurane]. ( Enzan, K; Horiguchi, T; Kadosaki, M; Komatsu, H; Suzuki, M, 1993)
"Seventeen myasthenia gravis and seven control patients were studied mechano (MMG)- and electromyographically (EMG) during isoflurane/oxygen/air anaesthesia."7.68Neuromuscular effects of isoflurane in patients with myasthenia gravis. ( Muller, K; Nilsson, E, 1990)
"Although several studies of the use of desflurane in anesthesia have revealed many desirable qualities, there are no data on the use and effects especially on the neuromuscular function of desflurane on myasthenia gravis (MG) patients."5.14The use of desflurane or propofol in combination with remifentanil in myasthenic patients undergoing a video-assisted thoracoscopic-extended thymectomy. ( Benigni, A; Bortolotti, G; Carrara, B; Giardini, D; Gritti, P; Khotcholava, M; Lanterna, LA; Sonzogni, V, 2009)
"We describe the use of isoflurane for the management of a 3-yr-old boy with congenital myasthenia gravis who required ventilation for pneumonia."3.69Isoflurane for sedation in a case of congenital myasthenia gravis. ( McBeth, C; Watkins, TG, 1996)
" In the first, isoflurane alone is administered, and mivacurium with isoflurane is administered to the second patient with myasthenia gravis."3.68Isoflurane and mivacurium chloride neuromuscular blockade in patients with myasthenia gravis. ( Mangar, D; Stillwell, R; Turnage, WS, 1993)
"We studied neuromuscular blocking effects of isoflurane using a neuromuscular transmission monitor in three myasthenia gravis patients."3.68[Severity of myasthenia gravis is related to the degree of neuromuscular blocking effect by isoflurane]. ( Enzan, K; Horiguchi, T; Kadosaki, M; Komatsu, H; Suzuki, M, 1993)
"Seventeen myasthenia gravis and seven control patients were studied mechano (MMG)- and electromyographically (EMG) during isoflurane/oxygen/air anaesthesia."3.68Neuromuscular effects of isoflurane in patients with myasthenia gravis. ( Muller, K; Nilsson, E, 1990)
"A 45-year-old man with cryptorchism, who was known to suffer from generalized myasthenia gravis, was admitted to hospital for surgical treatment using laparoscopy."1.31Combination of balanced and regional anaesthesia for minimally invasive surgery in a patient with myasthenia gravis. ( Albrecht, DM; Hübler, M; Litz, RJ, 2000)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's4 (50.00)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koda, K1
Kimura, H1
Uzawa, M1
Sambe, N1
Sugano, T1
Kitamura, T1
Tagami, M1
Gritti, P1
Carrara, B1
Khotcholava, M1
Bortolotti, G1
Giardini, D1
Lanterna, LA1
Benigni, A1
Sonzogni, V1
Stillwell, R1
Mangar, D1
Turnage, WS1
Kadosaki, M1
Enzan, K1
Horiguchi, T1
Komatsu, H1
Suzuki, M1
McBeth, C1
Watkins, TG1
Hübler, M1
Litz, RJ1
Albrecht, DM1
Nilsson, E1
Muller, K1
Rowbottom, SJ1

Trials

1 trial available for isoflurane and Myasthenia Gravis

ArticleYear
The use of desflurane or propofol in combination with remifentanil in myasthenic patients undergoing a video-assisted thoracoscopic-extended thymectomy.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:3

    Topics: Adolescent; Adult; Anesthesia; Desflurane; Drug Combinations; Female; Humans; Isoflurane; Male; Midd

2009

Other Studies

7 other studies available for isoflurane and Myasthenia Gravis

ArticleYear
[Desflurane anesthesia without muscle relaxant for a patient with myasthenia gravis undergoing laparoscopic high anterior resection: a case report].
    Masui. The Japanese journal of anesthesiology, 2014, Volume: 63, Issue:10

    Topics: Aged, 80 and over; Anesthesia, General; Contraindications; Desflurane; Digestive System Surgical Pro

2014
Isoflurane and mivacurium chloride neuromuscular blockade in patients with myasthenia gravis.
    Nurse anesthesia, 1993, Volume: 4, Issue:4

    Topics: Adult; Anesthesia; Drug Monitoring; Drug Therapy, Combination; Electromyography; Female; Humans; Iso

1993
[Severity of myasthenia gravis is related to the degree of neuromuscular blocking effect by isoflurane].
    Masui. The Japanese journal of anesthesiology, 1993, Volume: 42, Issue:6

    Topics: Female; Humans; Isoflurane; Male; Middle Aged; Myasthenia Gravis; Neuromuscular Blocking Agents; Neu

1993
Isoflurane for sedation in a case of congenital myasthenia gravis.
    British journal of anaesthesia, 1996, Volume: 77, Issue:5

    Topics: Anesthetics, Inhalation; Child, Preschool; Conscious Sedation; Humans; Isoflurane; Male; Myasthenia

1996
Combination of balanced and regional anaesthesia for minimally invasive surgery in a patient with myasthenia gravis.
    European journal of anaesthesiology, 2000, Volume: 17, Issue:5

    Topics: Abdomen; Amides; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Lo

2000
Neuromuscular effects of isoflurane in patients with myasthenia gravis.
    Acta anaesthesiologica Scandinavica, 1990, Volume: 34, Issue:2

    Topics: Adult; Anesthesia, Inhalation; Antibodies; Depression, Chemical; Female; HLA-B8 Antigen; Humans; Iso

1990
Isoflurane for thymectomy in myasthenia gravis.
    Anaesthesia and intensive care, 1989, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Anesthesia, General; Anesthesia, Inhalation; Electromyography; Female; Humans; Is

1989