Page last updated: 2024-10-29

isoflurane and Muscle Relaxation

isoflurane has been researched along with Muscle Relaxation in 32 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
"We did anesthetic management by isoflurane for total thyroidectomy under the neuromuscular transmission monitoring in a patient with myotonic dystrophy."7.68[Effect of isoflurane on muscle relaxation in a patient with myotonic dystrophy]. ( Enzan, K; Horiguchi, T; Komatsu, H; Satoh, W; Shouji, K; Suzuki, M, 1991)
"We did anesthetic management by isoflurane for total thyroidectomy under the neuromuscular transmission monitoring in a patient with myotonic dystrophy."3.68[Effect of isoflurane on muscle relaxation in a patient with myotonic dystrophy]. ( Enzan, K; Horiguchi, T; Komatsu, H; Satoh, W; Shouji, K; Suzuki, M, 1991)
"Mivacurium was administered in increments of 25 micrograms kg-1 until a depression of T1 > 95% was reached."2.69[Augmentation of the neuromuscular blocking effect of mivacurium during inhalation anesthesia with desflurane, sevoflorane and isoflurane in comparison with total intravenous anesthesia]. ( Hauschild, S; Ledowski, T; Proppe, D; Wulf, H, 1998)
"The presence of gagging, coughing, laryngospasm and movement was noted and graded."2.67Patient response to laryngeal mask insertion after induction of anaesthesia with propofol or thiopentone. ( Carey, M; Kirby, F; Power, M; Scanlon, P, 1993)
"Isoflurane or halothane was then administered."1.32Role of protein kinase C, Ca2+/calmodulin-dependent protein kinase II, and mitogen-activated protein kinases in volatile anesthetic-induced relaxation in newborn rabbit pulmonary artery. ( Su, JY; Vo, AC, 2003)
"Halothane was more potent in relaxing distal as compared to proximal bronchi; this differential effect was less pronounced with isoflurane and not observed with desflurane."1.31Relaxation of proximal and distal isolated human bronchi by halothane, isoflurane and desflurane. ( Advenier, C; Bardou, M; Benhamou, D; Denjean, A; Georges, O; Mercier, FJ; Naline, E, 2002)
"Isoflurane 1% was added after stabilization of twitch tension and MR was added 60 min later."1.29The effect of isoflurane and temperature on the actions of muscle relaxants in rat in vitro. ( Aziz, L; Hirakawa, M; Morita, K; Ohta, Y; Yamada, T, 1995)
" A dose-response curve was obtained for each airway ring with log increments of acetylcholine."1.29Topographical differences in the direct effects of isoflurane on airway smooth muscle. ( Bosnjak, ZJ; Cheng, EY; Coon, RL; Kampine, JP; Mazzeo, AJ; Stadnicka, A, 1994)
"The isoflurane response was independent of cyclooxygenase inhibition."1.28Isoflurane produces endothelium-independent relaxation in canine middle cerebral arteries. ( Bosnjak, ZJ; Buljubasic, N; Flynn, NM; Kampine, JP, 1992)
"Halothane was found to be a significantly more potent vasodilator of the isolated basilar artery than was isoflurane."1.28A comparison of the vasodilating effects of halothane and isoflurane on the isolated rabbit basilar artery with and without intact endothelium. ( Jensen, NF; Kramer, DJ; Leonard, PA; Todd, MM; Warner, DS, 1992)
"Isoflurane did not cause significant relaxation of K(+)-induced (60 mM) contractions at any concentration studied."1.28Halothane relaxes previously constricted human epicardial coronary artery segments more than isoflurane. ( Bollen, BA; McKlveen, RE; Stevenson, JA, 1992)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19903 (9.38)18.7374
1990's22 (68.75)18.2507
2000's6 (18.75)29.6817
2010's1 (3.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bukhari, Q1
Schroeter, A1
Rudin, M1
Hanazaki, M1
Chiba, Y1
Yokoyama, M1
Morita, K2
Kohjitani, A1
Sakai, H1
Misawa, M1
Mercier, FJ1
Naline, E1
Bardou, M1
Georges, O1
Denjean, A1
Benhamou, D1
Advenier, C1
Bouhemad, B1
Langeron, O1
Orliaguet, G1
Coriat, P1
Riou, B1
Su, JY1
Vo, AC1
Yu, J1
Ogawa, K1
Tokinaga, Y1
Iwahashi, S1
Hatano, Y2
Nagahama, S1
Nishimura, R1
Mochizuki, M1
Sasaki, N1
Eger, EI1
Yamamoto, K1
Morimoto, N1
Warner, DO1
Rehder, K1
Jones, KA1
Aziz, L1
Ohta, Y1
Yamada, T1
Hirakawa, M1
Akata, T1
Nakashima, M1
Kodama, K1
Boyle, WA1
Takahashi, S1
Diefenbach, C1
Lynch, J1
Abel, M1
Buzello, W1
Mazzeo, AJ2
Cheng, EY2
Stadnicka, A1
Bosnjak, ZJ3
Coon, RL2
Kampine, JP3
Scanlon, P1
Carey, M1
Power, M1
Kirby, F1
Nakamura, K1
Toda, H1
Mori, K1
Ide, T1
Kochi, T1
Isono, S1
Mizuguchi, T1
Jing, M1
Bina, S1
Verma, A1
Hart, JL1
Muldoon, SM1
Oshima, Y1
Ishibe, Y1
Okazaki, N1
Sato, T1
Eguchi, T1
Kitano, T1
Shingu, C1
Matsumoto, S1
Oda, S1
Taniguchi, K1
Noguchi, T1
Wulf, H1
Hauschild, S1
Proppe, D1
Ledowski, T1
Wiklund, CU1
Lim, S1
Lindsten, U1
Lindahl, SG1
Bollen, BA2
McKlveen, RE2
Stevenson, JA2
Hausmann, D1
Ebeling, B1
Nadstawek, J1
Müller, W1
Flynn, NM1
Buljubasic, N1
Jensen, NF1
Todd, MM1
Kramer, DJ1
Leonard, PA1
Warner, DS1
Komatsu, H1
Horiguchi, T1
Enzan, K1
Satoh, W1
Shouji, K1
Suzuki, M1
van der Spek, AF1
Reynolds, PI1
Fang, WB1
Ashton-Miller, JA1
Stohler, CS1
Schork, MA1
Gintautas, J1
Gintautiene, K1
Pillalamarri, ED1
Doss, NW1
Chaudhry, R1
Berman, S1
Longmore, W1
Abadir, AR1
Henry, RT1
Casto, R1
Hausdörfer, J1
Hagemann, H1
Bell, M1
Mertinat, M1

Trials

5 trials available for isoflurane and Muscle Relaxation

ArticleYear
The effects of propofol, isoflurane and sevoflurane on vecuronium infusion rates for surgical muscle relaxation in dogs.
    Veterinary anaesthesia and analgesia, 2006, Volume: 33, Issue:3

    Topics: Anesthesia, General; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Cross-Over Studies; D

2006
Patient response to laryngeal mask insertion after induction of anaesthesia with propofol or thiopentone.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:9

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Cough; Extremities; Female; Gagging; Head; H

1993
[Augmentation of the neuromuscular blocking effect of mivacurium during inhalation anesthesia with desflurane, sevoflorane and isoflurane in comparison with total intravenous anesthesia].
    Anaesthesiologie und Reanimation, 1998, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Desflur

1998
Changes in resistance to mouth opening induced by depolarizing and non-depolarizing neuromuscular relaxants.
    British journal of anaesthesia, 1990, Volume: 64, Issue:1

    Topics: Analysis of Variance; Anesthesia, Inhalation; Child; Facial Muscles; Female; Humans; Isoflurane; Mal

1990
[Isoflurane in pediatric anesthesia].
    Der Anaesthesist, 1986, Volume: 35, Issue:6

    Topics: Age Factors; Anesthesia; Carbon Dioxide; Child; Child, Preschool; Female; Halothane; Hemodynamics; H

1986

Other Studies

27 other studies available for isoflurane and Muscle Relaxation

ArticleYear
Increasing isoflurane dose reduces homotopic correlation and functional segregation of brain networks in mice as revealed by resting-state fMRI.
    Scientific reports, 2018, Jul-12, Volume: 8, Issue:1

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Brain Mapping; Cerebral Cortex; Consciousn

2018
Y-27632 augments the isoflurane-induced relaxation of bronchial smooth muscle in rats.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2008, Volume: 44, Issue:6

    Topics: Acetylcholine; Amides; Anesthetics, Inhalation; Animals; Asthma; Bronchi; Disease Models, Animal; Do

2008
Relaxation of proximal and distal isolated human bronchi by halothane, isoflurane and desflurane.
    The European respiratory journal, 2002, Volume: 20, Issue:2

    Topics: Anesthetics, Inhalation; Bronchi; Desflurane; Dose-Response Relationship, Drug; Halothane; Humans; I

2002
Effects of halothane and isoflurane on the contraction, relaxation and energetics of rat diaphragmatic muscle.
    British journal of anaesthesia, 2002, Volume: 89, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Diaphragm; Energy Metabolism; Halothane; Isoflurane; Isometric Con

2002
Role of protein kinase C, Ca2+/calmodulin-dependent protein kinase II, and mitogen-activated protein kinases in volatile anesthetic-induced relaxation in newborn rabbit pulmonary artery.
    Anesthesiology, 2003, Volume: 99, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinase Type

2003
The vascular relaxing effects of sevoflurane and isoflurane are more important in hypertensive than in normotensive rats.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:10

    Topics: Anesthetics, Inhalation; Angiotensin II; Animals; Aorta; Dose-Response Relationship, Drug; Endotheli

2004
Isoflurane: its place in anesthesia.
    Contemporary anesthesia practice, 1983, Volume: 7

    Topics: Anesthetics; Biotransformation; Blood Circulation; Central Nervous System; Humans; Isoflurane; Methy

1983
Factors influencing the direct actions of volatile anesthetics on airway smooth muscle.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Dogs;

1993
The effect of isoflurane and temperature on the actions of muscle relaxants in rat in vitro.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:6

    Topics: Animals; Body Temperature; Diaphragm; Drug Synergism; In Vitro Techniques; Isoflurane; Male; Muscle

1995
Effects of volatile anesthetics on acetylcholine-induced relaxation in the rabbit mesenteric resistance artery.
    Anesthesiology, 1995, Volume: 82, Issue:1

    Topics: Acetylcholine; Anesthetics, Inhalation; Animals; Electrophysiology; Enflurane; Ethers; Isoflurane; M

1995
Vecuronium for muscle relaxation in patients with dystrophia myotonica.
    Anesthesia and analgesia, 1993, Volume: 76, Issue:4

    Topics: Adult; Anesthesia; Female; Humans; Isoflurane; Male; Middle Aged; Muscle Relaxation; Myotonic Dystro

1993
Topographical differences in the direct effects of isoflurane on airway smooth muscle.
    Anesthesia and analgesia, 1994, Volume: 78, Issue:5

    Topics: Animals; Dogs; Female; Isoflurane; Male; Muscle Relaxation; Muscle, Smooth; Respiratory System

1994
Comparison of the direct effects of sevoflurane, isoflurane and halothane on isolated canine coronary arteries.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:3

    Topics: Anesthetics; Animals; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Ethers; Halothane; I

1993
Diaphragmatic activity during isoflurane anaesthesia in dogs.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:3

    Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Carbon Dioxide; Diaphragm; Dogs; Dose-Response Rela

1993
Differential effects of desflurane and halothane on peripheral airway smooth muscle.
    British journal of anaesthesia, 1996, Volume: 76, Issue:6

    Topics: Acetylcholine; Anesthetics, Inhalation; Animals; Bronchi; Desflurane; Dogs; Dose-Response Relationsh

1996
Effects of halothane and isoflurane on carbon monoxide-induced relaxations in the rat aorta.
    Anesthesiology, 1996, Volume: 85, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Aorta, Thoracic; Binding Sites; Carbon Dioxide; Cyclic GMP; Drug I

1996
Isoflurane inhibits endothelium-mediated nitric oxide relaxing pathways in the isolated perfused rabbit lung.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:10

    Topics: Acetylcholine; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Endothelium, Vasc

1997
[The relationship between maintenance dose of vecuronium and the recovery time from the muscle relaxation].
    Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:4

    Topics: Aged; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Inhalation

1998
Relaxation by sevoflurane, desflurane and halothane in the isolated guinea-pig trachea via inhibition of cholinergic neurotransmission.
    British journal of anaesthesia, 1999, Volume: 83, Issue:3

    Topics: Acetylcholine; Anesthetics, Inhalation; Animals; Cholinergic Fibers; Culture Techniques; Desflurane;

1999
Halothane relaxes preconstricted small and medium isolated porcine coronary artery segments more than isoflurane.
    Anesthesia and analgesia, 1992, Volume: 75, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
[Muscle relaxation with no effect on oxygen uptake during isoflurane anesthesia?].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1992, Volume: 27, Issue:8

    Topics: Abdomen; Adult; Anesthesia, Inhalation; Humans; Isoflurane; Middle Aged; Muscle Relaxation; Oxygen C

1992
Isoflurane produces endothelium-independent relaxation in canine middle cerebral arteries.
    Anesthesiology, 1992, Volume: 76, Issue:3

    Topics: Animals; Arginine; Cerebral Arteries; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Isof

1992
A comparison of the vasodilating effects of halothane and isoflurane on the isolated rabbit basilar artery with and without intact endothelium.
    Anesthesiology, 1992, Volume: 76, Issue:4

    Topics: Animals; Basilar Artery; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Endothelium,

1992
Halothane relaxes previously constricted human epicardial coronary artery segments more than isoflurane.
    Anesthesia and analgesia, 1992, Volume: 75, Issue:1

    Topics: Coronary Vessels; Halothane; Humans; In Vitro Techniques; Isoflurane; Muscle Relaxation; Muscle, Smo

1992
[Effect of isoflurane on muscle relaxation in a patient with myotonic dystrophy].
    Masui. The Japanese journal of anesthesiology, 1991, Volume: 40, Issue:11

    Topics: Adult; Anesthesia, Inhalation; Female; Humans; Isoflurane; Muscle Relaxation; Myotonic Dystrophy; Th

1991
Effect of volatile anesthetics on segmental relaxation of cerebral arteries.
    Proceedings of the Western Pharmacology Society, 1990, Volume: 33

    Topics: Anesthetics; Animals; Basilar Artery; Cerebral Arteries; Dogs; Halothane; In Vitro Techniques; Isofl

1990
Simple and inexpensive delivery of halogenated inhalation anesthetics to rodents.
    The American journal of physiology, 1989, Volume: 257, Issue:3 Pt 2

    Topics: Anesthesia, Inhalation; Animals; Cardiovascular Physiological Phenomena; Costs and Cost Analysis; Eq

1989