isoflurane has been researched along with Muscle Contraction in 87 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the pharmacokinetics, pharmacodynamics and the concentration-effect relationship of rocuronium in patients under stable propofol or isoflurane anesthesia." | 9.10 | Rocuronium pharmacokinetic-pharmacodynamic relationship under stable propofol or isoflurane anesthesia. ( Donati, F; Dragne, A; Plaud, B; Varin, F, 2002) |
| "To examine the effects of discontinuing sevoflurane or isoflurane anesthesia (1 minimum alveolar anesthetic concentration [MAC] of end-tidal concentrations, together with 66% N2O/O2) on the reversal of vecuronium-induced neuromuscular blockade (an initial dose = 100 micrograms/kg), the electromyographic response of the abductor digiti minimi was monitored at 20-s intervals after train-of-four (TOF) stimulation of the ulnar nerve in 192 ASA grades I and II patients." | 7.69 | Inadequate antagonism of vecuronium-induced neuromuscular block by neostigmine during sevoflurane or isoflurane anesthesia. ( Fujita, T; Morita, T; Saito, S; Sato, H; Sugaya, T; Tsukagoshi, H, 1995) |
| "To compare the pharmacokinetics, pharmacodynamics and the concentration-effect relationship of rocuronium in patients under stable propofol or isoflurane anesthesia." | 5.10 | Rocuronium pharmacokinetic-pharmacodynamic relationship under stable propofol or isoflurane anesthesia. ( Donati, F; Dragne, A; Plaud, B; Varin, F, 2002) |
| " Anesthesia was induced with thiopental and maintained with isoflurane/nitrous oxide in eight volunteers (study group) and seven surgical patients (control group)." | 5.07 | The effect of hypothermia on adductor pollicis twitch tension during continuous infusion of vecuronium in isoflurane-anesthetized humans. ( Caldwell, JE; Eriksson, LI; Heier, T; Miller, RD; Sessler, DI, 1994) |
| " The aim of this study was to investigate the effects of desflurane at different concentrations and durations in an ovalbumin-sensitized guinea pig model of airway hyper-responsiveness." | 3.85 | Time- and Dose-Dependent Effects of Desflurane in Sensitized Airways. ( Iwasaki, S; Yamakage, M; Zhou, J, 2017) |
| " Tyrosine kinase-catalyzed protein tyrosine phosphorylation plays an important role in regulating vascular smooth muscle contraction." | 3.73 | Comparison of the effects of isoflurane and sevoflurane on protein tyrosine phosphorylation-mediated vascular contraction. ( Hasegawa, A; Hatano, Y; Kakutani, T; Mizumoto, K; Ogawa, K; Yu, J, 2005) |
| "Because exposure to low temperature can modify the effect of volatile anesthetics on airway smooth muscle contraction, this study was conducted to investigate low-temperature modifications of the inhibitory effects of isoflurane and sevoflurane on canine tracheal smooth muscle tone by simultaneously measuring the muscle tension and intracellular concentration of Ca2+ ([Ca2+]i) and by measuring voltage-dependent Ca2+ channel activity." | 3.70 | Low-temperature modification of the inhibitory effects of volatile anesthetics on airway smooth muscle contraction in dogs. ( Hattori, J; Kamada, Y; Namiki, A; Tsujiguchi, N; Yamakage, M, 2000) |
| "We investigated the direct interaction between the volatile anesthetics, isoflurane and sevoflurane, and hypoxia in porcine tracheal smooth muscle in vitro by simultaneously measuring muscle tension and intracellular concentration of free Ca(2+) ([Ca2+]i)." | 3.70 | Interaction between volatile anesthetics and hypoxia in porcine tracheal smooth muscle. ( Chen, X; Kamada, Y; Namiki, A; Tsujiguchi, N; Yamakage, M, 2000) |
| "To examine the effects of discontinuing sevoflurane or isoflurane anesthesia (1 minimum alveolar anesthetic concentration [MAC] of end-tidal concentrations, together with 66% N2O/O2) on the reversal of vecuronium-induced neuromuscular blockade (an initial dose = 100 micrograms/kg), the electromyographic response of the abductor digiti minimi was monitored at 20-s intervals after train-of-four (TOF) stimulation of the ulnar nerve in 192 ASA grades I and II patients." | 3.69 | Inadequate antagonism of vecuronium-induced neuromuscular block by neostigmine during sevoflurane or isoflurane anesthesia. ( Fujita, T; Morita, T; Saito, S; Sato, H; Sugaya, T; Tsukagoshi, H, 1995) |
| "5 hr, to a 28-yr-old healthy, previously non-asthmatic man during thiopentone-O2/N2O-isoflurane anaesthesia for treatment and prophylaxis of bronchospasm." | 3.68 | Potentiation of pancuronium and vecuronium neuromuscular blockade by intravenous salbutamol. ( Donati, F; Salib, Y, 1993) |
| " Because mild hypothermia is common during general anesthesia, the authors sought to determine the relationship between the core temperature, adductor pollicis muscle temperature, and the twitch response of the adductor pollicis muscle, during isoflurane anesthesia in 15 patients undergoing elective surgery in which muscle relaxants were not required." | 3.67 | The relationship between adductor pollicis twitch tension and core, skin, and muscle temperature during nitrous oxide-isoflurane anesthesia in humans. ( Caldwell, JE; Heier, T; Kitts, JB; Miller, RD; Sessler, DI, 1989) |
| "Studies were conducted on the effects of isoflurane and halothane on intracellular mechanisms of striated muscle contraction: Ca2+ activation of the contractile proteins and Ca2+ uptake and release from the sarcoplasmic reticulum." | 3.67 | Intracellular mechanism of action of isoflurane and halothane on striated muscle of the rabbit. ( Bell, JG; Su, JY, 1986) |
| "Rocuronium was administered in increments of 100 micrograms." | 2.69 | Neuromuscular blocking effects of rocuronium during desflurane, isoflurane, and sevoflurane anaesthesia. ( Ledowski, T; Linstedt, U; Proppe, D; Sitzlack, D; Wulf, H, 1998) |
| " Pharmacokinetic analysis was performed using NONMEM." | 2.68 | Mild hypothermia alters propofol pharmacokinetics and increases the duration of action of atracurium. ( Bjorksten, AR; Leslie, K; Moayeri, A; Sessler, DI, 1995) |
| " In eight subjects, vecuronium bolus dose potency was determined using a two-dose dose-response technique; the vecuronium infusion dose requirement to achieve 85% twitch depression also was determined." | 2.68 | The magnitude and time course of vecuronium potentiation by desflurane versus isoflurane. ( Brown, R; Fisher, DM; Gruenke, L; Hart, P; Lau, M; Sharma, ML; Wright, PM, 1995) |
| "We were interested in determining the dose-response relationship of atracurium in children (2-10 yr) during nitrous oxide-isoflurane anesthesia (1%) and the atracurium infusion rate required to maintain about 95% neuromuscular blockade during nitrous oxide-halothane (0." | 2.66 | Atracurium infusion requirements in children during halothane, isoflurane, and narcotic anesthesia. ( Brandom, BW; Cook, DR; Fehr, B; Lineberry, CG; Rudd, GD; Woelfel, SK, 1985) |
| "Malignant hyperthermia is a potentially lethal inherited hypermetabolic syndrome that develops in susceptible individuals following administration of depolarising neuromuscular relaxants or volatile anaesthetics." | 1.37 | In-vitro contracture testing for susceptibility to malignant hyperthermia: can halothane be replaced? ( Anetseder, M; Kranke, P; Metterlein, T; Roewer, N; Schuster, F, 2011) |
| "Urethane is a common and often preferred anesthetic agent for urodynamic recordings in rats, but its use is often restricted to terminal procedures because of a prolonged duration of action and potentially toxic effects." | 1.35 | Differential effects of urethane and isoflurane on external urethral sphincter electromyography and cystometry in rats. ( Chang, HY; Havton, LA, 2008) |
| "Isoflurane induced a 40% increase in attachment step duration in both strains and an almost twofold increase in the CB cycle duration compared with baseline in Lewis rats." | 1.33 | The effects of isoflurane on airway smooth muscle crossbridge kinetics in Fisher and Lewis rats. ( Blanc, FX; Coirault, C; David, JS; Duracher, C; Gueugniaud, PY; Lecarpentier, Y; Riou, B, 2005) |
| "A 3% halothane-induced increase in [Ca2+]cyt was observed in the Ca(2+)-free solution even when the muscle strip was pretreated with a 10(-6)-M dose of ryanodine and a 20-mM dose of caffeine, whereas it was abolished completely after the muscle strip was pretreated with ryanodine, caffeine, and 100 nM norepinephrine." | 1.29 | Effects of halothane and isoflurane on cytosolic calcium ion concentrations and contraction in the vascular smooth muscle of the rat aorta. ( Fujita, S; Namba, H; Namiki, A; Notsuki, E; Tsuchida, H; Yamakage, M, 1993) |
| " The preparations were then exposed to up to 4 vol% volatile agent incrementally to generate a cumulative dose-response curve, and the subsequent frequency of peristaltic contractions was determined." | 1.29 | Volatile anesthetics decrease peristalsis in the guinea pig ureter. ( Attele, A; Moss, J; Núñez, R; Toledano, A; Young, CJ, 1994) |
| "Halothane or isoflurane was aerated into four tissue baths, while the remaining four served as time controls." | 1.29 | Effects of halothane and isoflurane on antigen- and leukotriene-D4-induced constriction of guinea pig trachea. ( Bosnjak, ZJ; Coon, RL; Kampine, JP; Tudoric, N, 1995) |
| "Isoflurane may cause differential effects on different vascular beds of the same animal species." | 1.29 | Mechanisms of action of isoflurane on contraction of rabbit conduit artery. ( Su, JY, 1996) |
| "Isoflurane has a lesser ability than halothane to induce contracture in malignant hyperthermia (MH) muscle in vitro." | 1.28 | Effect of Bay K 8644 on the magnitude of isoflurane and halothane contracture of skeletal muscle from patients susceptible to malignant hyperthermia. ( Adamantidis, MM; Adnet, PJ; Haudecoeur, G; Imbenotte, M; Krivosic-Horber, RM; Reyford, H, 1992) |
| " Birds were randomly assigned to 4 groups, and atracurium was administered at dosage of 0." | 1.28 | Neuromuscular and cardiovascular effects of atracurium in isoflurane-anesthetized chickens. ( Ilkiw, JE; Nicholson, A, 1992) |
| "A halothane-induced increase in time-to-peak contraction was also observed at membrane potentials in the range of the action potential plateau (+20 and +40 mV)." | 1.28 | Influence of halothane on contraction at positive membrane potentials in single cells isolated from guinea-pig ventricular muscle. ( Terrar, DA; Victory, JG, 1989) |
| "Isoflurane has been shown to depress skeletal muscle force in vitro, but data are not available regarding the effects of isoflurane on diaphragmatic muscle function in vivo." | 1.28 | Effects of isoflurane on contractile properties of diaphragm. ( Aubier, M; Desmonts, JM; Dureuil, B; Pariente, R; Veber, B; Viires, N, 1989) |
| " The dose-response curve was shifted significantly to the left during nitrous oxide-isoflurane anaesthesia (ED50 0." | 1.27 | Neuromuscular and cardiovascular effects of atracurium during nitrous oxide-fentanyl and nitrous oxide-isoflurane anaesthesia. ( Fahey, MR; Miller, RD; Rupp, SM, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (16.09) | 18.7374 |
| 1990's | 45 (51.72) | 18.2507 |
| 2000's | 21 (24.14) | 29.6817 |
| 2010's | 5 (5.75) | 24.3611 |
| 2020's | 2 (2.30) | 2.80 |
| Authors | Studies |
|---|---|
| Aizawa, N | 1 |
| Fujita, T | 2 |
| Xu, JJ | 1 |
| Yousuf, Z | 1 |
| Ouyang, Z | 1 |
| Kennedy, E | 1 |
| Lester, PA | 1 |
| Martin, T | 1 |
| Bruns, TM | 1 |
| Dryn, D | 1 |
| Luo, J | 1 |
| Melnyk, M | 1 |
| Zholos, A | 1 |
| Hu, H | 1 |
| Zhou, J | 1 |
| Iwasaki, S | 1 |
| Yamakage, M | 5 |
| Allard, J | 1 |
| Edmunds, NJ | 1 |
| Chang, HY | 1 |
| Havton, LA | 1 |
| Blatt, LK | 1 |
| Lashinger, ES | 1 |
| Laping, NJ | 1 |
| Su, X | 1 |
| Metterlein, T | 1 |
| Schuster, F | 1 |
| Kranke, P | 1 |
| Roewer, N | 1 |
| Anetseder, M | 1 |
| Shimogai, M | 1 |
| Ogawa, K | 3 |
| Tokinaga, Y | 2 |
| Yamazaki, A | 1 |
| Hatano, Y | 4 |
| Campion, SN | 1 |
| Cappon, GD | 1 |
| Chapin, RE | 1 |
| Jamon, RT | 1 |
| Winton, TR | 1 |
| Nowland, WS | 1 |
| Bouhemad, B | 2 |
| Langeron, O | 2 |
| Orliaguet, G | 2 |
| Coriat, P | 2 |
| Riou, B | 3 |
| Motamed, C | 1 |
| Donati, F | 4 |
| Nishina, K | 1 |
| Mikawa, K | 1 |
| Kodama, SI | 1 |
| Kagawa, T | 1 |
| Uesugi, T | 1 |
| Obara, H | 1 |
| Lecarpentier, Y | 2 |
| Kopman, AF | 1 |
| Zhaku, B | 1 |
| Lai, KS | 1 |
| Pandya, AB | 1 |
| O'Leary, CE | 1 |
| Rapp, HJ | 1 |
| Altenmueller, CA | 1 |
| Waschke, C | 1 |
| Hannon, JD | 1 |
| Cody, MJ | 1 |
| Sun, DX | 1 |
| Housmans, PR | 2 |
| Yu, J | 2 |
| Mizumoto, K | 2 |
| Kakutani, T | 2 |
| Hasegawa, A | 1 |
| Duracher, C | 1 |
| Blanc, FX | 1 |
| Gueugniaud, PY | 1 |
| David, JS | 1 |
| Coirault, C | 1 |
| Chelu, MG | 1 |
| Goonasekera, SA | 1 |
| Durham, WJ | 1 |
| Tang, W | 1 |
| Lueck, JD | 1 |
| Riehl, J | 1 |
| Pessah, IN | 1 |
| Zhang, P | 1 |
| Bhattacharjee, MB | 1 |
| Dirksen, RT | 1 |
| Hamilton, SL | 1 |
| Rupp, SM | 1 |
| Fahey, MR | 1 |
| Miller, RD | 3 |
| Bevan, DR | 1 |
| Takita, K | 1 |
| Goda, Y | 1 |
| Kemmotsu, O | 1 |
| Mashio, H | 1 |
| Okuyama, A | 1 |
| Ito, Y | 1 |
| Sakamoto, H | 1 |
| Kawahigashi, H | 1 |
| Shi, Y | 1 |
| Keykhah, MM | 1 |
| Storella, RJ | 1 |
| Rosenberg, H | 1 |
| Tsuchida, H | 3 |
| Namba, H | 2 |
| Fujita, S | 2 |
| Notsuki, E | 1 |
| Namiki, A | 5 |
| Yamamoto, K | 1 |
| Morimoto, N | 1 |
| Warner, DO | 2 |
| Rehder, K | 1 |
| Jones, KA | 2 |
| Leslie, K | 1 |
| Sessler, DI | 3 |
| Bjorksten, AR | 1 |
| Moayeri, A | 1 |
| Morita, T | 1 |
| Tsukagoshi, H | 1 |
| Sugaya, T | 1 |
| Saito, S | 1 |
| Sato, H | 1 |
| Wright, PM | 1 |
| Hart, P | 1 |
| Lau, M | 1 |
| Brown, R | 1 |
| Sharma, ML | 1 |
| Gruenke, L | 1 |
| Fisher, DM | 1 |
| Akata, T | 2 |
| Boyle, WA | 1 |
| Brull, SJ | 1 |
| Connelly, NR | 1 |
| Silverman, DG | 1 |
| Heier, T | 2 |
| Caldwell, JE | 2 |
| Eriksson, LI | 2 |
| Ozhan, M | 1 |
| Sill, JC | 3 |
| Atagunduz, P | 1 |
| Martin, R | 1 |
| Katusić, ZS | 1 |
| Young, CJ | 1 |
| Attele, A | 1 |
| Toledano, A | 1 |
| Núñez, R | 1 |
| Moss, J | 1 |
| Salib, Y | 1 |
| Saitoh, Y | 4 |
| Toyooka, H | 2 |
| Amaha, K | 6 |
| Seki, S | 1 |
| Tanaka, S | 2 |
| Kohro, S | 1 |
| Kawamata, T | 1 |
| Ide, T | 1 |
| Kochi, T | 1 |
| Isono, S | 1 |
| Mizuguchi, T | 1 |
| Tudoric, N | 1 |
| Coon, RL | 1 |
| Kampine, JP | 2 |
| Bosnjak, ZJ | 2 |
| Su, JY | 2 |
| Kim, DW | 1 |
| Joshi, GP | 1 |
| White, PF | 1 |
| Johnson, ER | 1 |
| Mercier, FJ | 1 |
| Denjean, A | 1 |
| Kaneko, K | 2 |
| Kawai, S | 1 |
| Fuchigami, Y | 1 |
| Shiraishi, G | 1 |
| Ito, T | 1 |
| Fang, Z | 1 |
| Sonner, J | 1 |
| Laster, MJ | 1 |
| Ionescu, P | 1 |
| Kandel, L | 1 |
| Koblin, DD | 1 |
| Eger, EI | 1 |
| Halsey, MJ | 1 |
| Koitabashi, Y | 1 |
| Makita, K | 3 |
| Tanaka, H | 3 |
| Dutton, RC | 1 |
| Smith, WD | 1 |
| Bennett, HL | 1 |
| Archer, S | 1 |
| Smith, NT | 1 |
| Wulf, H | 1 |
| Ledowski, T | 1 |
| Linstedt, U | 1 |
| Proppe, D | 1 |
| Sitzlack, D | 1 |
| Fujii, Y | 2 |
| Kai, T | 1 |
| Bremerich, DH | 1 |
| Lugo, SI | 1 |
| Liang, Z | 1 |
| Eddington, ND | 1 |
| Hirata, S | 1 |
| Enoki, T | 1 |
| Kitamura, R | 1 |
| Vinh, VH | 1 |
| Nakamura, K | 2 |
| Mori, K | 2 |
| Wiklund, CU | 1 |
| Lim, S | 1 |
| Lindsten, U | 1 |
| Lindahl, SG | 1 |
| Tsujiguchi, N | 2 |
| Hattori, J | 1 |
| Kamada, Y | 2 |
| Chen, X | 1 |
| Jellish, WS | 1 |
| Brody, M | 1 |
| Sawicki, K | 1 |
| Slogoff, S | 1 |
| Izumi, K | 1 |
| Takahashi, S | 1 |
| Dragne, A | 1 |
| Varin, F | 1 |
| Plaud, B | 1 |
| Kinder, MV | 1 |
| Bos, R | 1 |
| Janknegt, R | 1 |
| Marani, E | 1 |
| Waud, BE | 1 |
| Waud, DR | 1 |
| Munson, ES | 1 |
| Embro, WJ | 1 |
| Klide, AM | 1 |
| Adnet, PJ | 1 |
| Krivosic-Horber, RM | 1 |
| Adamantidis, MM | 1 |
| Haudecoeur, G | 1 |
| Reyford, H | 1 |
| Imbenotte, M | 1 |
| Bollen, BA | 1 |
| McKlveen, RE | 1 |
| Stevenson, JA | 1 |
| Oshima, T | 1 |
| Nicholson, A | 1 |
| Ilkiw, JE | 1 |
| Mather, C | 1 |
| Raftery, S | 1 |
| Prys-Roberts, C | 1 |
| Flynn, N | 1 |
| Buljubasic, N | 1 |
| Freas, W | 1 |
| Llave, R | 1 |
| Hart, J | 1 |
| Golightly, D | 1 |
| Nagel, J | 1 |
| Muldoon, S | 1 |
| Lennmarken, C | 1 |
| Staun, P | 1 |
| Viby-Mogensen, J | 1 |
| Baele, P | 1 |
| Villeneuve, E | 1 |
| Blaise, G | 2 |
| Guerard, MJ | 1 |
| Buluran, J | 1 |
| Girard, D | 1 |
| Yakushiji, T | 1 |
| Nishiwada, M | 1 |
| Anaes, FC | 1 |
| Terrar, DA | 1 |
| Victory, JG | 1 |
| Kitts, JB | 1 |
| Reynolds, PI | 1 |
| Fang, WB | 1 |
| VanDerSpek, AF | 1 |
| Shibata, T | 1 |
| Blanck, TJ | 1 |
| Sagawa, K | 1 |
| Hunter, W | 1 |
| Veber, B | 1 |
| Dureuil, B | 1 |
| Viires, N | 1 |
| Aubier, M | 1 |
| Pariente, R | 1 |
| Desmonts, JM | 1 |
| Brandom, BW | 1 |
| Cook, DR | 1 |
| Woelfel, SK | 1 |
| Rudd, GD | 1 |
| Fehr, B | 1 |
| Lineberry, CG | 1 |
| Nugent, M | 1 |
| Van Dyke, RA | 1 |
| Vanhoutte, PM | 1 |
| Iwatsuki, N | 1 |
| Shiratori, T | 1 |
| Fudeta, H | 1 |
| Shiozawa, S | 1 |
| Bell, JG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Standard Normothermia Protocol On Surgical Site Infections: Randomized Controlled Trial[NCT02961244] | 118 participants (Actual) | Interventional | 2013-06-30 | Completed | |||
| Comparison of the Effect of Continuous Infusion and Bolus Doses of Rocuronium During Anesthesia for Lumbal Discectomy on Muscle Strength and Quality of Patient Recovery[NCT04236050] | 80 participants (Actual) | Interventional | 2015-12-31 | Completed | |||
| Pharmacokinetic and Pharmacodynamic of Rocuronium Bromide Measured in Adductor Pollicis and Masseter Muscles.[NCT02376595] | 10 participants (Actual) | Observational | 2013-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Within the surgery day, from patient bed through the operating room to PACU or ICU or back to patient bed.~With these results our intervention group's maintaining normothermia rates were higher respectively. ( p=0.001) For each patients around 11 temperature measurement had been made according to the operation time . If any measurement of any patients was <36 ºC , that patient accepted as hypothermic. (Failure to maintain normothermia)" (NCT02961244)
Timeframe: Surgery day
| Intervention | Participants (Count of Participants) |
|---|---|
| Control Group | 7 |
| Intervention Group | 26 |
"Within the postoperative 30 days, if there is purulent exudate or nonpurulent but culture was pozitive, we accepted them as Surgical Site Infection (SSI) diagnosed.~All patients were made enough incision wide to explore their entire abdomen defined as Major Abdominal Surgery .~With this results between two groups intervention group had lesser rates of SSI respectively( (p=0.045 Mann Whitney U, n<30), (p=0.044 chi-square )" (NCT02961244)
Timeframe: Postoperative 30 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Control Group | 19 |
| Intervention Group | 8 |
17 trials available for isoflurane and Muscle Contraction
| Article | Year |
|---|---|
Sevoflurane and isoflurane, but not propofol, decrease mivacurium requirements over time.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Drug Synergism; | 2002 |
The "intubating dose" of succinylcholine: the effect of decreasing doses on recovery time.
Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Desflurane; Dose-Response Relationship, Drug | 2003 |
Neuromuscular recovery following rocuronium bromide single dose in infants.
Topics: Age Factors; Analgesia, Epidural; Analysis of Variance; Androstanols; Anesthesia Recovery Period; An | 2004 |
Potentiation of succinylcholine phase II block with isoflurane.
Topics: Adult; Drug Synergism; Female; Fentanyl; Humans; Infusions, Parenteral; Isoflurane; Male; Methyl Eth | 1983 |
Mild hypothermia alters propofol pharmacokinetics and increases the duration of action of atracurium.
Topics: Adult; Anesthesia; Atracurium; Female; Humans; Hypothermia, Induced; Indocyanine Green; Isoflurane; | 1995 |
The magnitude and time course of vecuronium potentiation by desflurane versus isoflurane.
Topics: Adult; Cross-Over Studies; Desflurane; Dose-Response Relationship, Drug; Drug Synergism; Female; Hum | 1995 |
The effect of hypothermia on adductor pollicis twitch tension during continuous infusion of vecuronium in isoflurane-anesthetized humans.
Topics: Adult; Anesthesia; Female; Humans; Hypothermia, Induced; Infusions, Intravenous; Isoflurane; Male; M | 1994 |
Interactions between mivacurium, rocuronium, and vecuronium during general anesthesia.
Topics: Adult; Androstanols; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Desflur | 1996 |
Train-of-four and double burst stimulation fade at the great toe and thumb.
Topics: Adult; Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Electric Stimulation | 1997 |
Craniofacial electromyogram activation response: another indicator of anesthetic depth.
Topics: Adolescent; Adult; Anesthesia, General; Anesthetics, Inhalation; Brain; Communication; Electric Stim | 1998 |
Neuromuscular blocking effects of rocuronium during desflurane, isoflurane, and sevoflurane anaesthesia.
Topics: Adult; Androstanols; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; An | 1998 |
Modified double burst stimulation of varying stimulating currents.
Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Anesthetics, Inhalation; Electric Stimulati | 1998 |
Post-tetanic burst count and train-of-four during recovery from vecuronium-induced intense neuromuscular block under different types of anaesthesia.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Inhalat | 1998 |
Recovery from neuromuscular blockade after either bolus and prolonged infusions of cisatracurium or rocuronium using either isoflurane or propofol-based anesthetics.
Topics: Androstanols; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Female; Humans; Infusio | 2000 |
Rocuronium pharmacokinetic-pharmacodynamic relationship under stable propofol or isoflurane anesthesia.
Topics: Adult; Aged; Androstanols; Anesthesia; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, In | 2002 |
Use of post-tetanic count in assessment of a repetitive vecuronium-induced neuromuscular block.
Topics: Adult; Anesthesia, General; Droperidol; Female; Fentanyl; Humans; Isoflurane; Male; Middle Aged; Mus | 1990 |
Atracurium infusion requirements in children during halothane, isoflurane, and narcotic anesthesia.
Topics: Anesthesia, General; Atracurium; Child; Child, Preschool; Dose-Response Relationship, Drug; Fentanyl | 1985 |
70 other studies available for isoflurane and Muscle Contraction
| Article | Year |
|---|---|
Comparison of the effects of two anesthetics, isoflurane and urethane, on bladder function in rats.
Topics: Amides; Anesthetics; Anesthetics, Intravenous; Animals; Carbamates; Female; Isoflurane; Muscle Contr | 2023 |
Anesthetic agents affect urodynamic parameters and anesthetic depth at doses necessary to facilitate preclinical testing in felines.
Topics: Anesthesia Recovery Period; Anesthetics; Animals; Cats; Chloralose; Dexmedetomidine; Dose-Response R | 2020 |
Inhalation anaesthetic isoflurane inhibits the muscarinic cation current and carbachol-induced gastrointestinal smooth muscle contractions.
Topics: Anesthetics, Inhalation; Animals; Calcium; Carbachol; Electrophysiological Phenomena; Intestines; In | 2018 |
Time- and Dose-Dependent Effects of Desflurane in Sensitized Airways.
Topics: Airway Resistance; Anesthetics, Inhalation; Animals; Carbachol; Cholinergic Agents; Cyclic AMP; Desf | 2017 |
Reflex penile erection in anesthetized mice: an exploratory study.
Topics: alpha-MSH; Anesthesia; Animals; Area Under Curve; Blood Pressure; Dose-Response Relationship, Radiat | 2008 |
Differential effects of urethane and isoflurane on external urethral sphincter electromyography and cystometry in rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Electromyography; Female; Isoflurane; Mo | 2008 |
Evaluation of pressor and visceromotor reflex responses to bladder distension in urethane anesthetized rats.
Topics: Abdominal Muscles; Analgesics; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Pre | 2009 |
In-vitro contracture testing for susceptibility to malignant hyperthermia: can halothane be replaced?
Topics: Anesthetics, Inhalation; Biopsy; Case-Control Studies; Desflurane; Dose-Response Relationship, Drug; | 2011 |
The cellular mechanisms underlying the inhibitory effects of isoflurane and sevoflurane on arginine vasopressin-induced vasoconstriction.
Topics: Actin Cytoskeleton; Anesthetics, Inhalation; Animals; Aorta, Thoracic; Arginine Vasopressin; Calcium | 2010 |
Isoflurane reduces motile sperm counts in the Sprague-Dawley rat.
Topics: Anesthetics, Inhalation; Animal Welfare; Animals; Carbon Dioxide; Euthanasia, Animal; Image Processi | 2012 |
Effects of halothane and isoflurane on the contraction, relaxation and energetics of rat diaphragmatic muscle.
Topics: Anesthetics, Inhalation; Animals; Diaphragm; Energy Metabolism; Halothane; Isoflurane; Isometric Con | 2002 |
The effects of enflurane, isoflurane, and intravenous anesthetics on rat diaphragmatic function and fatigability.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Diaphragm; Electric Stimulation; Enflura | 2003 |
Effects of halogenated anaesthetics on diaphragmatic actin-myosin cross-bridge kinetics.
Topics: Actins; Anesthetics, Inhalation; Animals; Culture Techniques; Diaphragm; Halothane; Isoflurane; Musc | 2003 |
Development of malignant hyperthermia post-cardiopulmonary bypass during surgery for mitral valve replacement.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Cardiopulmonary Bypas | 2003 |
Effects of isoflurane and sevoflurane on intracellular calcium and contractility in pressure-overload hypertrophy.
Topics: Aequorin; Anesthetics, Inhalation; Animals; Blood Pressure; Blotting, Western; Calcium; Electric Sti | 2004 |
The inhibitory effects of isoflurane on protein tyrosine phosphorylation-modulated contraction of rat aortic smooth muscle.
Topics: Anesthetics, Inhalation; Animals; Aorta, Thoracic; Blotting, Western; Dose-Response Relationship, Dr | 2004 |
Comparison of the effects of isoflurane and sevoflurane on protein tyrosine phosphorylation-mediated vascular contraction.
Topics: Anesthetics, Inhalation; Animals; Aorta, Thoracic; Enzyme Inhibitors; Genistein; In Vitro Techniques | 2005 |
The effects of isoflurane on airway smooth muscle crossbridge kinetics in Fisher and Lewis rats.
Topics: Algorithms; Anesthetics, Inhalation; Animals; In Vitro Techniques; Isoflurane; Kinetics; Muscle Cont | 2005 |
Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse.
Topics: Anesthesia; Anesthetics; Animals; Caffeine; Calcium; Disease Models, Animal; Hot Temperature; Isoflu | 2006 |
Neuromuscular and cardiovascular effects of atracurium during nitrous oxide-fentanyl and nitrous oxide-isoflurane anaesthesia.
Topics: Anesthesia, General; Atracurium; Blood Pressure; Dose-Response Relationship, Drug; Fentanyl; Heart R | 1983 |
Secondary hyperparathyroidism shortens the action of vecuronium in patients with chronic renal failure.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Case-Control Studies; Electromyography; Female; Fen | 1995 |
Effect of different volatile anaesthetics on suxamethonium-induced jaw muscle contracture in rats.
Topics: Anesthetics; Animals; Desflurane; Halothane; Hot Temperature; Isoflurane; Male; Masticatory Muscles; | 1995 |
Effects of halothane and isoflurane on cytosolic calcium ion concentrations and contraction in the vascular smooth muscle of the rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Factors influencing the direct actions of volatile anesthetics on airway smooth muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Dogs; | 1993 |
Inadequate antagonism of vecuronium-induced neuromuscular block by neostigmine during sevoflurane or isoflurane anesthesia.
Topics: Adult; Anesthesia; Anesthetics; Dose-Response Relationship, Drug; Ethers; Female; Humans; Isoflurane | 1995 |
Volatile anesthetic actions on contractile proteins in membrane-permeabilized small mesenteric arteries.
Topics: Animals; Calcium; Cell Membrane Permeability; Contractile Proteins; Enflurane; Escin; Halothane; In | 1995 |
Recovery of train-of-four after mivacurium.
Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Endotracheal; Cholinesterases; Elec | 1995 |
Volatile anesthetics and agonist-induced contractions in porcine coronary artery smooth muscle and Ca2+ mobilization in cultured immortalized vascular smooth muscle cells.
Topics: Aluminum Compounds; Animals; Calcium; Cells, Cultured; Coronary Vessels; Dose-Response Relationship, | 1994 |
Volatile anesthetics decrease peristalsis in the guinea pig ureter.
Topics: Animals; Dose-Response Relationship, Drug; Enflurane; Guinea Pigs; Halothane; In Vitro Techniques; I | 1994 |
Potentiation of pancuronium and vecuronium neuromuscular blockade by intravenous salbutamol.
Topics: Adult; Albuterol; Anesthesia, Inhalation; Anesthesia, Intravenous; Blood Pressure; Bronchial Spasm; | 1993 |
Relationship between post-tetanic twitch and single twitch response after administration of vecuronium.
Topics: Adult; Anesthesia, Inhalation; Anesthetics; Enflurane; Ethers; Female; Halothane; Humans; Isoflurane | 1993 |
Role of intracellular Ca2+ pools in the effects of halothane and isoflurane on vascular smooth muscle contraction.
Topics: Animals; Calcium; Halothane; In Vitro Techniques; Ion Transport; Isoflurane; Male; Muscle Contractio | 1994 |
Inhibitory effects of four inhaled anesthetics on canine tracheal smooth muscle contraction and intracellular Ca2+ concentration.
Topics: Anesthetics; Animals; Calcium; Carbachol; Dogs; Drug Interactions; Enflurane; Ethers; Halothane; Iso | 1993 |
Diaphragmatic activity during isoflurane anaesthesia in dogs.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Carbon Dioxide; Diaphragm; Dogs; Dose-Response Rela | 1993 |
Effects of halothane and isoflurane on antigen- and leukotriene-D4-induced constriction of guinea pig trachea.
Topics: Anesthetics, Inhalation; Animals; Guinea Pigs; Halothane; In Vitro Techniques; Isoflurane; Leukotrie | 1995 |
Mechanisms of action of isoflurane on contraction of rabbit conduit artery.
Topics: Animals; Aorta; Caffeine; Calcium; Endothelium, Vascular; Femoral Artery; Isoflurane; Male; Muscle C | 1996 |
Guinea-pig tracheal responsiveness in vitro following general anaesthesia with halothane.
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Guinea Pigs; Halothane; In Vitro Techniques; | 1996 |
Effect of stimulus intensity and voluntary contraction on corticospinal potentials following transcranial magnetic stimulation.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Brachial Plexus; Evoked Potentials; Female; Hum | 1996 |
Anesthetic and convulsant properties of aromatic compounds and cycloalkanes: implications for mechanisms of narcosis.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Benzene; Benzene Derivatives; Convulsants; | 1996 |
Drug-specific effects of volatile anesthetics on Ca2+ sensitization in airway smooth muscle.
Topics: Acetylcholine; Anesthetics, Inhalation; Animals; Calcium; Dogs; Escin; Female; Guanosine Triphosphat | 1998 |
Effects of halothane and isoflurane on beta-adrenoceptor-mediated responses in the vascular smooth muscle of rat aorta.
Topics: Adrenergic beta-Agonists; Anesthetics, Inhalation; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; | 1998 |
Pharmacokinetics and pharmacodynamics of mivacurium stereoisomers in beagle dogs using twitch height and train-of-four response.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Chromatography, High Pressure Liquid; Dogs; Female; Is | 1998 |
Effects of isoflurane on receptor-operated Ca2+ channels in rat aortic smooth muscle.
Topics: Anesthetics, Inhalation; Animals; Aorta, Thoracic; Calcium; Calcium Channels; Culture Techniques; Dr | 1998 |
Relaxation by sevoflurane, desflurane and halothane in the isolated guinea-pig trachea via inhibition of cholinergic neurotransmission.
Topics: Acetylcholine; Anesthetics, Inhalation; Animals; Cholinergic Fibers; Culture Techniques; Desflurane; | 1999 |
Low-temperature modification of the inhibitory effects of volatile anesthetics on airway smooth muscle contraction in dogs.
Topics: Anesthetics, Inhalation; Animals; Calcium Channels; Cold Temperature; Dogs; Dose-Response Relationsh | 2000 |
Interaction between volatile anesthetics and hypoxia in porcine tracheal smooth muscle.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Calcium; Calcium Signaling; Carbachol; Chela | 2000 |
Role of endothelium in the action of isoflurane on vascular smooth muscle of isolated mesenteric resistance arteries.
Topics: Acetylcholine; Anesthetics, Inhalation; Animals; Endothelium, Vascular; In Vitro Techniques; Isoflur | 2001 |
Demonstration of spontaneous and stretch induced urinary bladder EMG in the living rabbit.
Topics: Animals; Blood Pressure; Butyrophenones; Drug Combinations; Electromyography; Electrophysiology; Fen | 2001 |
Effects of volatile anesthetics on directly and indirectly stimulated skeletal muscle.
Topics: Anesthetics; Animals; Electric Stimulation; Enflurane; Ether; Ethers; Guinea Pigs; Halothane; In Vit | 1979 |
Enflurane, isoflurane, and halothane and isolated human uterine muscle.
Topics: Adult; Depression, Chemical; Enflurane; Female; Halothane; Humans; Isoflurane; Methyl Ethers; Muscle | 1977 |
Cardiopulmonary effects of enflurane and isoflurane in the dog.
Topics: Anesthesia, Inhalation; Animals; Aorta; Blood Pressure; Cardiac Output; Dogs; Enflurane; Female; Hea | 1976 |
Effect of Bay K 8644 on the magnitude of isoflurane and halothane contracture of skeletal muscle from patients susceptible to malignant hyperthermia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Halothane relaxes preconstricted small and medium isolated porcine coronary artery segments more than isoflurane.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Sternocleidomastoid muscle contractility at different levels of isoflurane anaesthesia in humans.
Topics: Adolescent; Adult; Anesthesia, Inhalation; Dose-Response Relationship, Drug; Humans; Isoflurane; Mal | 1992 |
Neuromuscular and cardiovascular effects of atracurium in isoflurane-anesthetized chickens.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Animals; Atracurium; Blood Pressure; Chickens; D | 1992 |
Somatic movement and oesophageal motility during isoflurane anaesthesia.
Topics: Adult; Aged; Anesthesia, Inhalation; Dose-Response Relationship, Drug; Esophagus; Female; Humans; Is | 1992 |
Cerebral vascular responses to anesthetics.
Topics: Anesthetics; Animals; Arginine; Calcium Channels; Cerebral Arteries; Cerebrovascular Circulation; Do | 1991 |
Interactions of volatile anesthetics and reactive oxygen intermediates on vascular smooth muscle.
Topics: Anesthetics; Animals; Calcium; Calcium Channels; Cell Membrane; Dogs; Free Radicals; Halothane; In V | 1991 |
The effects of halothane, enflurane, and isoflurane on the length-tension relation of the isolated ventricular papillary muscle of the ferret.
Topics: Animals; Depression, Chemical; Enflurane; Ferrets; Halothane; In Vitro Techniques; Isoflurane; Male; | 1991 |
Halothane 1.5 MAC, isoflurane 1.5 MAC, and the contractile responses of coronary arteries obtained from human hearts.
Topics: Adult; Coronary Vessels; Dinoprost; Female; Halothane; Histamine; Humans; In Vitro Techniques; Isofl | 1991 |
Comparison of the direct effects of halothane and isoflurane on large and small coronary arteries isolated from dogs.
Topics: Adenosine; Animals; Coronary Vessels; Dogs; Female; Halothane; In Vitro Techniques; Isoflurane; Male | 1990 |
[Effects of sevoflurane and enflurane on isometric tension and maximum velocity of shortening in glycerinated guinea pig masseter muscles].
Topics: Anesthetics; Animals; Ethers; Guinea Pigs; In Vitro Techniques; Isoflurane; Masseter Muscle; Methyl | 1990 |
Influence of halothane on contraction at positive membrane potentials in single cells isolated from guinea-pig ventricular muscle.
Topics: Animals; Guinea Pigs; Halothane; In Vitro Techniques; Isoflurane; Membrane Potentials; Muscle Contra | 1989 |
The relationship between adductor pollicis twitch tension and core, skin, and muscle temperature during nitrous oxide-isoflurane anesthesia in humans.
Topics: Anesthesia, Inhalation; Body Temperature; Electric Stimulation; Humans; Hypothermia; Hypothermia, In | 1989 |
The onset of ablation of the evoked adductor pollicis muscle twitch in children: a clinical perspective.
Topics: Adolescent; Anesthesia, Inhalation; Child; Child, Preschool; Depression, Chemical; Electric Stimulat | 1988 |
The effect of halothane, enflurane, and isoflurane on the dynamic stiffness of rabbit papillary muscle.
Topics: Animals; Barium; Dose-Response Relationship, Drug; Enflurane; Halothane; Isoflurane; Muscle Contract | 1989 |
Effects of isoflurane on contractile properties of diaphragm.
Topics: Animals; Diaphragm; Isoflurane; Muscle Contraction; Rats | 1989 |
Isoflurane causes endothelium-dependent inhibition of contractile responses of canine coronary arteries.
Topics: Animals; Coronary Vessels; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Isoflurane; Mal | 1987 |
[Contracture response to isoflurane and pentazocine in muscles of a patient with malignant hyperthermia].
Topics: Caffeine; Child; Halothane; Humans; In Vitro Techniques; Isoflurane; Male; Malignant Hyperthermia; M | 1986 |
Intracellular mechanism of action of isoflurane and halothane on striated muscle of the rabbit.
Topics: Animals; Caffeine; Calcium; Drug Interactions; Halothane; In Vitro Techniques; Isoflurane; Methyl Et | 1986 |