isoflurane and Meningioma studies

isoflurane and Meningioma

isoflurane has been researched along with Meningioma in 3 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Meningioma: A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)

Research Excerpts

Excerpt	Relevance	Reference
"When conventional treatment for status epilepticus fails, general anaesthesia is recommended."	5.28	Isoflurane in the management of status epilepticus after surgery for lesion around the motor area. ( Abe, K; Furuya, H; Hoshida, T; Miyamoto, S; Morimoto, T; Okuchi, K; Sakaki, T; Tsunoda, S, 1992)
"When conventional treatment for status epilepticus fails, general anaesthesia is recommended."	1.28	Isoflurane in the management of status epilepticus after surgery for lesion around the motor area. ( Abe, K; Furuya, H; Hoshida, T; Miyamoto, S; Morimoto, T; Okuchi, K; Sakaki, T; Tsunoda, S, 1992)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (66.67)	18.2507
2000's	1 (33.33)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

2 (66.67)

18.2507

2000's

1 (33.33)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Wang, JL	1
Xie, WX	1
Zhang, Q	1
Todd, MM	1
Warner, DS	1
Sokoll, MD	1
Maktabi, MA	1
Hindman, BJ	1
Scamman, FL	1
Kirschner, J	1
Sakaki, T	1
Abe, K	1
Hoshida, T	1
Morimoto, T	1
Tsunoda, S	1
Okuchi, K	1
Miyamoto, S	1
Furuya, H	1

Studies

Wang, JL

Xie, WX

Zhang, Q

Todd, MM

Warner, DS

Sokoll, MD

Maktabi, MA

Hindman, BJ

Scamman, FL

Kirschner, J

Sakaki, T

Abe, K

Hoshida, T

Morimoto, T

Tsunoda, S

Okuchi, K

Miyamoto, S

Furuya, H

Clinical Trials (4)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
Anaesthesia for Supratentorial Tumor Resection : a Double-blind Comparison of Target Plasma Concentration of Propofol-remifentanil and Sevoflurane-sufentanil[NCT00389883]	Phase 3	69 participants (Actual)	Interventional	2006-11-30	Completed
Anesthesiological Strategies in Elective Craniotomy: Randomized, Equivalence, Open Trial[NCT00741351]	Phase 3	411 participants (Actual)	Interventional	2007-12-31	Completed
The Effect of Furosemide Versus Placebo on Brain Relaxation and Incidence of Significant Intravascular Volume Depletion in Human Subjects Receiving Mannitol[NCT01054404]		23 participants (Actual)	Interventional	2010-02-28	Terminated (stopped due to Concern for volume depletion and electrolyte abnormalities in furosemide arm.)
Clinical Effectiveness of Hypertonic Sodium Lactate Infusion for Intraoperative Brain Relaxation in Patients Undergoing Scheduled Craniotomy for Supratentorial Brain Tumor Resection: Study Protocol of a Single Center Double-blind Randomized Controlled Pha[NCT04488874]	Phase 3	50 participants (Actual)	Interventional	2020-09-29	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial

Phase

Enrollment

Study Type

Start Date

Status

Anaesthesia for Supratentorial Tumor Resection : a Double-blind Comparison of Target Plasma Concentration of Propofol-remifentanil and Sevoflurane-sufentanil[NCT00389883]

Phase 3

69 participants (Actual)

Interventional

2006-11-30

Completed

Anesthesiological Strategies in Elective Craniotomy: Randomized, Equivalence, Open Trial[NCT00741351]

Phase 3

411 participants (Actual)

Interventional

2007-12-31

Completed

The Effect of Furosemide Versus Placebo on Brain Relaxation and Incidence of Significant Intravascular Volume Depletion in Human Subjects Receiving Mannitol[NCT01054404]

23 participants (Actual)

Interventional

2010-02-28

Terminated (stopped due to Concern for volume depletion and electrolyte abnormalities in furosemide arm.)

Clinical Effectiveness of Hypertonic Sodium Lactate Infusion for Intraoperative Brain Relaxation in Patients Undergoing Scheduled Craniotomy for Supratentorial Brain Tumor Resection: Study Protocol of a Single Center Double-blind Randomized Controlled Pha[NCT04488874]

Phase 3

50 participants (Actual)

Interventional

2020-09-29

Completed

[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Acceptable vs. Unacceptable Brain Relaxation at Dural Opening

"Rating of brain relaxation will be on a 4-point scale:~0 = brain very relaxed under dura, acceptable~= brain adequately relaxed under dura, acceptable~= brain slightly tense under dura, acceptable~= brain very tense under bulging dura, unacceptable" (NCT01054404)
Timeframe: just prior to dural opening for each subject

Intervention	units on a scale 0-3 (Mean)
Furosemide	1.5
Placebo	1.3

Intervention

units on a scale 0-3 (Mean)

Furosemide

1.5

Placebo

1.3

Article	Year
[Effects of combined transdermal acupoint electric stimulation and isoflurane anesthesia on isoflurane-induced hypotension and tissue oxygen metabolism in patients undergoing craniotomy]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2001, Volume: 21, Issue:3 Topics: Acupuncture Points; Adult; Anesthetics, Inhalation; Craniotomy; Female; Humans; Hypotension, Control	2001
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide. Anesthesiology, 1993, Volume: 78, Issue:6 Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;	1993

Article

Year

[Effects of combined transdermal acupoint electric stimulation and isoflurane anesthesia on isoflurane-induced hypotension and tissue oxygen metabolism in patients undergoing craniotomy].

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2001, Volume: 21, Issue:3

Topics: Acupuncture Points; Adult; Anesthetics, Inhalation; Craniotomy; Female; Humans; Hypotension, Control

2001

A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.

Anesthesiology, 1993, Volume: 78, Issue:6