isoflurane has been researched along with Ischemic Attack, Transient in 32 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, we sought to clarify the role of inhibiting ubiquitin-conjugated protein aggregation in the formation of a neuroprotective effect after isoflurane preconditioning using a transient global cerebral ischemia-reperfusion injury mouse model." | 3.76 | Isoflurane preconditioning induces neuroprotection by attenuating ubiquitin-conjugated protein aggregation in a mouse model of transient global cerebral ischemia. ( Dong, HL; Ma, R; Tong, L; Xiong, L; Yuan, LB; Zhang, HP; Zhao, RN, 2010) |
| "A previous study indicated that diaspirin-crosslinked hemoglobin (DCLHb) decreases cerebral ischemia after subarachnoid hemorrhage." | 3.70 | Subarachnoid molecular hemoglobin after subarachnoid hemorrhage in rats: effect on the area of hypoperfusion. ( Cole, DJ; Cross, LM; Drummond, JC; McKay, LD; Patel, PM, 1998) |
| "Mice then underwent 2 h of middle cerebral artery occlusion and were evaluated 22 h later for infarct volume." | 1.36 | Isoflurane preconditioning neuroprotection in experimental focal stroke is androgen-dependent in male mice. ( Herson, PS; Hurn, PD; Libal, NL; Murphy, SJ; Palmateer, JM; Wang, L; Zhang, L; Zhu, W, 2010) |
| "In this study, we determined whether repeated brief isoflurane (Iso) anesthesia induces ischemic tolerance to focal cerebral ischemia in a dose-response manner and whether the effect is dependent on adenosine triphosphate-regulated potassium channels." | 1.32 | Preconditioning with isoflurane produces dose-dependent neuroprotection via activation of adenosine triphosphate-regulated potassium channels after focal cerebral ischemia in rats. ( Hou, L; Lu, Z; Wu, M; Xiong, L; Zhang, X; Zheng, Y; Zhu, Z, 2003) |
| "Isoflurane is an effective neuroprotective drug in a canine cardiac arrest model in terms of both functional and biochemical criteria." | 1.31 | Isoflurane pretreatment ameliorates postischemic neurologic dysfunction and preserves hippocampal Ca2+/calmodulin-dependent protein kinase in a canine cardiac arrest model. ( Adamo, A; Beckman, J; Blanck, TJ; Haile, M; Heerdt, P; Hemmings, H; Kang, R; Veselis, RA; Xu, F; Zhang, J, 2000) |
| "The presence of cerebral hemorrhage after reperfusion was checked macroscopically and infarct volume with 2,3,5-triphenyltetrazolium staining." | 1.30 | Hyperglycemia and the vascular effects of cerebral ischemia. ( Betz, AL; Kawai, N; Keep, RF, 1997) |
| "Seven days later, the volume of cerebral infarction in the animals was determined by image analysis of hematoxylin and eosin-stained coronal brain sections." | 1.30 | Fentanyl does not increase brain injury after focal cerebral ischemia in rats. ( Cole, DJ; Drummond, JC; Kelly, PJ; Patel, PM; Soonthon-Brant, V; Watson, M, 1999) |
| "Isoflurane has properties that suggest it may provide cerebral protection from ischemia." | 1.28 | Primate brain tolerance to temporary focal cerebral ischemia during isoflurane- or sodium nitroprusside-induced hypotension. ( Boisvert, DP; Dowman, R; Gelb, AW; Lam, AM; Marchak, BE; Mielke, BW; Tang, C, 1989) |
| "Isoflurane has protective properties during experimental global brain ischemia or hypoxia." | 1.27 | A comparison of the cerebral protective effects of isoflurane and barbiturates during temporary focal ischemia in primates. ( Drummond, JC; Johnson, PC; Nehls, DG; Spetzler, RF; Thompson, RA; Todd, MM, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (28.13) | 18.7374 |
| 1990's | 11 (34.38) | 18.2507 |
| 2000's | 6 (18.75) | 29.6817 |
| 2010's | 6 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamanaka, K | 1 |
| Inoue, S | 1 |
| Naito, Y | 1 |
| Kawaguchi, M | 1 |
| Zhang, HP | 2 |
| Sun, YY | 1 |
| Chen, XM | 1 |
| Yuan, LB | 2 |
| Su, BX | 1 |
| Ma, R | 2 |
| Zhao, RN | 2 |
| Dong, HL | 2 |
| Xiong, L | 3 |
| Zhang, H | 1 |
| Xiong, X | 1 |
| Liu, J | 1 |
| Gu, L | 1 |
| Li, F | 1 |
| Wan, Y | 1 |
| Xu, S | 1 |
| Wang, L | 2 |
| Kitano, H | 1 |
| Hurn, PD | 2 |
| Murphy, SJ | 2 |
| Zhu, W | 1 |
| Zhang, L | 1 |
| Palmateer, JM | 1 |
| Libal, NL | 1 |
| Herson, PS | 1 |
| Tong, L | 1 |
| Bedirli, N | 1 |
| Bagriacik, EU | 1 |
| Emmez, H | 1 |
| Yilmaz, G | 1 |
| Unal, Y | 1 |
| Ozkose, Z | 1 |
| Zheng, Y | 1 |
| Wu, M | 1 |
| Hou, L | 1 |
| Zhu, Z | 1 |
| Zhang, X | 1 |
| Lu, Z | 1 |
| Ritz, MF | 1 |
| Schmidt, P | 1 |
| Mendelowitsch, A | 1 |
| Sun, H | 1 |
| Zhao, H | 1 |
| Sharpe, GM | 1 |
| Arrick, DM | 1 |
| Mayhan, WG | 1 |
| Koorn, R | 1 |
| Kahn, RA | 1 |
| Brannan, TS | 1 |
| Martinez-Tica, J | 1 |
| Weinberger, J | 1 |
| Reich, DL | 1 |
| Illievich, UM | 1 |
| Zornow, MH | 1 |
| Choi, KT | 1 |
| Strnat, MA | 1 |
| Scheller, MS | 1 |
| Hoffman, WE | 1 |
| Charbel, FT | 1 |
| Edelman, G | 1 |
| Kawai, N | 1 |
| Keep, RF | 1 |
| Betz, AL | 1 |
| Lavine, SD | 1 |
| Masri, LS | 1 |
| Levy, ML | 1 |
| Giannotta, SL | 1 |
| Linstedt, U | 1 |
| Maier, C | 1 |
| Petry, A | 1 |
| Patel, PM | 3 |
| Drummond, JC | 4 |
| Cole, DJ | 3 |
| Kelly, PJ | 2 |
| Watson, M | 2 |
| McKay, LD | 1 |
| Cross, LM | 1 |
| Soonthon-Brant, V | 1 |
| Kamei, T | 1 |
| Isshiki, A | 1 |
| Blanck, TJ | 1 |
| Haile, M | 1 |
| Xu, F | 1 |
| Zhang, J | 1 |
| Heerdt, P | 1 |
| Veselis, RA | 1 |
| Beckman, J | 1 |
| Kang, R | 1 |
| Adamo, A | 1 |
| Hemmings, H | 1 |
| Abe, K | 1 |
| Iwanaga, H | 1 |
| Yoshiya, I | 1 |
| Lloyd-Thomas, AR | 1 |
| Cole, PV | 1 |
| Prior, PF | 1 |
| Adnet, P | 1 |
| Fesard, P | 1 |
| Riegel, B | 1 |
| Debout, J | 1 |
| Krivosic-Horber, R | 1 |
| Gelb, AW | 1 |
| Boisvert, DP | 1 |
| Tang, C | 1 |
| Lam, AM | 1 |
| Marchak, BE | 1 |
| Dowman, R | 1 |
| Mielke, BW | 1 |
| Milde, LN | 1 |
| Milde, JH | 1 |
| Lanier, WL | 1 |
| Michenfelder, JD | 2 |
| Adams, HA | 1 |
| Russ, W | 1 |
| Kling, D | 1 |
| Moosdorf, R | 1 |
| Hempelmann, G | 1 |
| Zatelli, R | 1 |
| Targa, L | 1 |
| Droghetti, L | 1 |
| Bovolenta, A | 1 |
| Baldi, M | 1 |
| Bottoni, M | 1 |
| Serra, G | 1 |
| Gozzo, E | 1 |
| Nehls, DG | 1 |
| Todd, MM | 1 |
| Spetzler, RF | 1 |
| Thompson, RA | 1 |
| Johnson, PC | 1 |
| Skydell, JL | 1 |
| Machleder, HI | 1 |
| Baker, JD | 1 |
| Busuttil, RW | 1 |
| Moore, WS | 1 |
| Frost, EA | 1 |
3 trials available for isoflurane and Ischemic Attack, Transient
| Article | Year |
|---|---|
Carbon dioxide reactivity and local cerebral blood flow during prostaglandin E1- or nitroglycerin-induced hypotension.
Topics: Adult; Aged; Alprostadil; Anesthesia, Inhalation; Blood Pressure; Carbon Dioxide; Cerebrovascular Ci | 1992 |
Isoflurane prevents EEG depression during trimetaphan-induced hypotension in man.
Topics: Adult; Aged; Anesthesia, Inhalation; Depression, Chemical; Electroencephalography; Female; Halothane | 1990 |
[Reaction of the sympathetic nervous system, cardiovascular parameters and endocrine stress response in disobliterating interventions of the carotid arteries. A comparison of isoflurane anesthesia and modified neurolepto-anesthesia].
Topics: Adult; Aged; Anesthesia, General; Carotid Artery Thrombosis; Endarterectomy; Energy Metabolism; Epin | 1988 |
29 other studies available for isoflurane and Ischemic Attack, Transient
| Article | Year |
|---|---|
Amiodarone does not affect brain injury in a rat model of transient forebrain ischemia.
Topics: Amiodarone; Anesthetics, Inhalation; Animals; CA1 Region, Hippocampal; Cardiopulmonary Resuscitation | 2019 |
The neuroprotective effects of isoflurane preconditioning in a murine transient global cerebral ischemia-reperfusion model: the role of the Notch signaling pathway.
Topics: Animals; Apoptosis; Ataxia; Basic Helix-Loop-Helix Transcription Factors; CA1 Region, Hippocampal; C | 2014 |
Emulsified Isoflurane Protects Against Transient Focal Cerebral Ischemia Injury in Rats via the PI3K/Akt Signaling Pathway.
Topics: Administration, Intravenous; Animals; Anti-Inflammatory Agents; Brain; Chemistry, Pharmaceutical; Cy | 2016 |
Estradiol attenuates neuroprotective benefits of isoflurane preconditioning in ischemic mouse brain.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Drug Implants; Estradiol; Estrogen Receptor alpha; | 2008 |
Isoflurane preconditioning neuroprotection in experimental focal stroke is androgen-dependent in male mice.
Topics: Androgens; Anesthetics, Inhalation; Animals; Aromatase; Aromatase Inhibitors; Brain; Dihydrotestoste | 2010 |
Isoflurane preconditioning induces neuroprotection by attenuating ubiquitin-conjugated protein aggregation in a mouse model of transient global cerebral ischemia.
Topics: Animals; Apoptosis; Blotting, Western; CA1 Region, Hippocampal; Cell Survival; Cerebrovascular Circu | 2010 |
Sevoflurane and isoflurane preconditioning provides neuroprotection by inhibition of apoptosis-related mRNA expression in a rat model of focal cerebral ischemia.
Topics: Anesthetics, Inhalation; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Brain Edem | 2012 |
Preconditioning with isoflurane produces dose-dependent neuroprotection via activation of adenosine triphosphate-regulated potassium channels after focal cerebral ischemia in rats.
Topics: Anesthetics, Inhalation; Animals; ATP-Binding Cassette Transporters; Blood Gas Analysis; Body Temper | 2003 |
Effects of isoflurane on glutamate and taurine releases, brain swelling and injury during transient ischemia and reperfusion.
Topics: Anesthetics; Animals; Brain Edema; Glutamic Acid; Ischemic Attack, Transient; Isoflurane; Male; Neur | 2006 |
Effect of chronic alcohol consumption on brain damage following transient focal ischemia.
Topics: Alcohol Drinking; Analgesics; Analysis of Variance; Animals; Body Weight; Brain Injuries; Cerebral A | 2008 |
Effect of isoflurane and halothane on in vivo ischemia-induced dopamine release in the corpus striatum of the rat. A study using cerebral microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blood Pressure; Chloral Hydrate; Corpus Striatum; Dopamine; | 1993 |
Effects of hypothermia or anesthetics on hippocampal glutamate and glycine concentrations after repeated transient global cerebral ischemia.
Topics: Animals; Female; Glutamates; Glycine; Hippocampus; Hypothermia, Induced; Ischemic Attack, Transient; | 1994 |
Brain tissue oxygen, carbon dioxide, and pH in neurosurgical patients at risk for ischemia.
Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Gas Analysis; Brain; Brain Ischemia; C | 1996 |
Hyperglycemia and the vascular effects of cerebral ischemia.
Topics: Anesthetics; Animals; Blood Glucose; Body Temperature; Cerebral Arteries; Cerebral Hemorrhage; Cereb | 1997 |
Temporary occlusion of the middle cerebral artery in intracranial aneurysm surgery: time limitation and advantage of brain protection.
Topics: Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Aneurysm, Ruptured; Brai | 1997 |
Intraoperative monitoring with somatosensory evoked potentials in carotid artery surgery--less reliable in patients with preoperative neurologic deficiency?
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Arteriovenous Shunt, Surgical; Atracurium; | 1998 |
Isoflurane and pentobarbital reduce the frequency of transient ischemic depolarizations during focal ischemia in rats.
Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cerebral Infarcti | 1998 |
Subarachnoid molecular hemoglobin after subarachnoid hemorrhage in rats: effect on the area of hypoperfusion.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Antipyrine; Aspirin; Blood; Blood Substitute | 1998 |
Fentanyl does not increase brain injury after focal cerebral ischemia in rats.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Blood Pressure; Body Temperature; Carbon Dioxi | 1999 |
[Changes in brain metabolites under combined mild-hypothermia and isoflurane anesthesia in rat with temporal brain ischemia].
Topics: Anesthesia, Inhalation; Animals; Brain; Energy Metabolism; Excitatory Amino Acids; Hypothermia, Indu | 2000 |
Isoflurane pretreatment ameliorates postischemic neurologic dysfunction and preserves hippocampal Ca2+/calmodulin-dependent protein kinase in a canine cardiac arrest model.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Blotting, Western; Brain Diseases; Calcium; Calciu | 2000 |
[Interaction of nimodipine and isoflurane in surgery of intracranial aneurysm].
Topics: Drug Interactions; Hemodynamics; Humans; Hypotension, Controlled; Intracranial Aneurysm; Intraoperat | 1989 |
Primate brain tolerance to temporary focal cerebral ischemia during isoflurane- or sodium nitroprusside-induced hypotension.
Topics: Animals; Brain; Female; Ferricyanides; Hypotension, Controlled; Ischemic Attack, Transient; Isoflura | 1989 |
Comparison of the effects of isoflurane and thiopental on neurologic outcome and neuropathology after temporary focal cerebral ischemia in primates.
Topics: Animals; Blood Gas Analysis; Blood Glucose; Blood Pressure; Brain; Cerebral Infarction; Electroencep | 1988 |
[Effect of the absorption of isoflurane on several cerebral electrophysiologic parameters].
Topics: Anesthesia, General; Brain; Electroencephalography; Evoked Potentials; Female; Humans; Ischemic Atta | 1987 |
Does isoflurane aggravate regional cerebral ischemia?
Topics: Animals; Drug Interactions; Hypertension; Ischemic Attack, Transient; Isoflurane; Papio; Phenylephri | 1987 |
A comparison of the cerebral protective effects of isoflurane and barbiturates during temporary focal ischemia in primates.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Electroencephalography; Evoked Potentials, Somatose | 1987 |
Incidence and mechanism of post-carotid endarterectomy hypertension.
Topics: Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Carotid Arteries; Diabetes Complication | 1987 |
Anesthesia for intracranial cerebrovascular disease.
Topics: Anesthesia; Anesthesia, Inhalation; Cerebral Revascularization; Humans; Ischemic Attack, Transient; | 1986 |