isoflurane has been researched along with Ischemia in 18 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We tested whether 1) extracellular vesicles (EVs) isolated from humans undergoing RIPC protect cardiomyoblasts against hypoxia-induced apoptosis and 2) this effect is altered by cardiomyoblast exposure to isoflurane or propofol." | 9.34 | Extracellular vesicles isolated from patients undergoing remote ischemic preconditioning decrease hypoxia-evoked apoptosis of cardiomyoblasts after isoflurane but not propofol exposure. ( Abel, F; Frey, UH; Gaida, M; Garnier, N; Giebel, B; Kleinbongard, P; Murke, F; Ochsenfarth, C; Peters, J; Theiss, C; Thielmann, M, 2020) |
| "We were able to determine the effects of the duration of anesthesia using isoflurane on the transcriptomes in the brains of rats at 24 h after tMCAO." | 8.31 | Isoflurane Anesthesia's Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model. ( Denisova, AE; Dergunova, LV; Filippenkov, IB; Gubsky, LV; Limborska, SA; Shpetko, YY; Stavchansky, VV, 2023) |
| "Early apoptosis was significantly higher in isoflurane and propofol anesthetized animals subjected to renal ischemia-reperfusion injury when compared to both cyclosporine A treated and sham groups." | 7.85 | Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats. ( Carvalho, LR; Castiglia, YM; Deffune, E; Golim, MA; Lemos, SV; Módolo, NS; Nascimento, PD; Souza, AV; Vianna, IG; Vianna, PT, 2017) |
| "Isoflurane has a pharmacological preconditioning effect against ischemia injury in the heart, kidney, and brain, but whether and how isoflurane preconditioning protects livers against ischemia and reperfusion (IR) injury is unclear." | 7.85 | Isoflurane Preconditioning Alleviated Murine Liver Ischemia and Reperfusion Injury by Restoring AMPK/mTOR-Mediated Autophagy. ( Ding, Z; Gao, M; Li, J; Liu, S; Lu, T; Pan, X; Rao, Z; Sun, J; Yu, D; Zhang, H, 2017) |
| "Hepatic ischemia induced significant degree of I/R injuries in both isoflurane and sevoflurane non-IP groups." | 7.85 | Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats. ( Gwak, MS; Han, S; Jeong, JS; Kim, D; Kim, GS; Kim, KY; Ko, JS; Ryu, S; Shin, BS, 2017) |
| "The Langendorff model was used to determine whether pretreatment with sevoflurane, isoflurane, or ischemic preconditioning (IP) could protect the myocardium of rats against global ischemia." | 7.70 | Administration of sevoflurane and isoflurane prior to prolonged global ischemia improves heart function in isolated rat heart. ( Hayes, JK; Li, F; Szakacs, J; Wong, KC, 2000) |
| "This study was designed to compare the effects of isoflurane and nitroprusside on spinal cord ischemia when they are used to control proximal hypertension during thoracic aortic cross-clamping (TACC)." | 7.69 | Isoflurane versus sodium nitroprusside for the control of proximal hypertension during thoracic aortic cross-clamping: effects on spinal cord ischemia. ( Clagnaz, JF; Eide, TR; Hossain, I; Newman, SB; Schiff, GA; Simpson, JI; Zisbrod, Z, 1995) |
| " We tested whether 1) extracellular vesicles (EVs) isolated from humans undergoing RIPC protect cardiomyoblasts against hypoxia-induced apoptosis and 2) this effect is altered by cardiomyoblast exposure to isoflurane or propofol." | 5.34 | Extracellular vesicles isolated from patients undergoing remote ischemic preconditioning decrease hypoxia-evoked apoptosis of cardiomyoblasts after isoflurane but not propofol exposure. ( Abel, F; Frey, UH; Gaida, M; Garnier, N; Giebel, B; Kleinbongard, P; Murke, F; Ochsenfarth, C; Peters, J; Theiss, C; Thielmann, M, 2020) |
| "Ischemia was induced by reducing the baseline perfusion pressure from 1." | 5.29 | Effects of halothane, isoflurane and sevoflurane on ischemia-reperfusion injury in the perfused liver of fasted rats. ( Imai, M; Inaba, H; Kon, S, 1996) |
| "We were able to determine the effects of the duration of anesthesia using isoflurane on the transcriptomes in the brains of rats at 24 h after tMCAO." | 4.31 | Isoflurane Anesthesia's Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model. ( Denisova, AE; Dergunova, LV; Filippenkov, IB; Gubsky, LV; Limborska, SA; Shpetko, YY; Stavchansky, VV, 2023) |
| "Early apoptosis was significantly higher in isoflurane and propofol anesthetized animals subjected to renal ischemia-reperfusion injury when compared to both cyclosporine A treated and sham groups." | 3.85 | Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats. ( Carvalho, LR; Castiglia, YM; Deffune, E; Golim, MA; Lemos, SV; Módolo, NS; Nascimento, PD; Souza, AV; Vianna, IG; Vianna, PT, 2017) |
| "Isoflurane has a pharmacological preconditioning effect against ischemia injury in the heart, kidney, and brain, but whether and how isoflurane preconditioning protects livers against ischemia and reperfusion (IR) injury is unclear." | 3.85 | Isoflurane Preconditioning Alleviated Murine Liver Ischemia and Reperfusion Injury by Restoring AMPK/mTOR-Mediated Autophagy. ( Ding, Z; Gao, M; Li, J; Liu, S; Lu, T; Pan, X; Rao, Z; Sun, J; Yu, D; Zhang, H, 2017) |
| "Hepatic ischemia induced significant degree of I/R injuries in both isoflurane and sevoflurane non-IP groups." | 3.85 | Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats. ( Gwak, MS; Han, S; Jeong, JS; Kim, D; Kim, GS; Kim, KY; Ko, JS; Ryu, S; Shin, BS, 2017) |
| "The results suggest that isoflurane preconditioning induces endothelial protection against in-vitro simulated ischemia." | 3.77 | Isoflurane preconditioning increases endothelial cell tolerance to in-vitro simulated ischaemia. ( Feng, J; Zuo, Z, 2011) |
| "This study was designed to compare the effects of isoflurane and nitroprusside on spinal cord ischemia when they are used to control proximal hypertension during thoracic aortic cross-clamping (TACC)." | 3.69 | Isoflurane versus sodium nitroprusside for the control of proximal hypertension during thoracic aortic cross-clamping: effects on spinal cord ischemia. ( Clagnaz, JF; Eide, TR; Hossain, I; Newman, SB; Schiff, GA; Simpson, JI; Zisbrod, Z, 1995) |
| "PONV was assessed in the early (0-4 h) and overall (0-24 h) postoperative period by an anaesthesiologist unaware of patients' treatment regime." | 2.75 | Supplemental oxygen reduces serotonin levels in plasma and platelets during colorectal surgery and reduces postoperative nausea and vomiting. ( Beschmann, R; Hamm, F; Ochmann, C; Piper, SN; Röhm, KD; Tuschy, B, 2010) |
| "Alfentanil infusion was used to prevent the increase of mean arterial pressure more than 25% from baseline." | 2.69 | Effects of esmolol on haemodynamic response to CO2 pneumoperitoneum for laparoscopic surgery. ( Koivusalo, AM; Laakso, J; Lindgren, L; Ristkari, S; Scheinin, M; Tikkanen, I; Yli-Suomu, T, 1998) |
| "Filamentous middle cerebral artery occlusion (fMCAO) is the most frequently used focal cerebral ischemia model in rodents." | 1.35 | Filamentous middle cerebral artery occlusion causes ischemic damage to the retina in mice. ( Guo, Q; Namura, S; Steele, EC, 2008) |
| "Ischemia was induced by reducing the baseline perfusion pressure from 1." | 1.29 | Effects of halothane, isoflurane and sevoflurane on ischemia-reperfusion injury in the perfused liver of fasted rats. ( Imai, M; Inaba, H; Kon, S, 1996) |
| "Halothane (1%) was associated with only an increased ATP concentration in tubules exposed to 30 min of ischemia." | 1.28 | The effect of halothane, isoflurane, and verapamil on ischemic-isolated rabbit renal tubules. ( Hjelmhaug, JA; Rice, MJ; Southard, JH, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Clarysse, M | 1 |
| Accarie, A | 1 |
| Farré, R | 1 |
| Canovai, E | 1 |
| Monbaliu, D | 1 |
| Gunst, J | 1 |
| De Hertogh, G | 1 |
| Vanuytsel, T | 1 |
| Pirenne, J | 1 |
| Ceulemans, LJ | 1 |
| Shpetko, YY | 1 |
| Filippenkov, IB | 1 |
| Denisova, AE | 1 |
| Stavchansky, VV | 1 |
| Gubsky, LV | 1 |
| Limborska, SA | 1 |
| Dergunova, LV | 1 |
| Abel, F | 1 |
| Murke, F | 1 |
| Gaida, M | 1 |
| Garnier, N | 1 |
| Ochsenfarth, C | 1 |
| Theiss, C | 1 |
| Thielmann, M | 1 |
| Kleinbongard, P | 1 |
| Giebel, B | 1 |
| Peters, J | 1 |
| Frey, UH | 1 |
| Lemos, SV | 1 |
| Vianna, IG | 1 |
| Castiglia, YM | 1 |
| Golim, MA | 1 |
| Souza, AV | 1 |
| Carvalho, LR | 1 |
| Deffune, E | 1 |
| Nascimento, PD | 1 |
| Módolo, NS | 1 |
| Vianna, PT | 1 |
| Rao, Z | 1 |
| Pan, X | 1 |
| Zhang, H | 1 |
| Sun, J | 1 |
| Li, J | 1 |
| Lu, T | 1 |
| Gao, M | 1 |
| Liu, S | 1 |
| Yu, D | 1 |
| Ding, Z | 1 |
| Jeong, JS | 1 |
| Kim, D | 1 |
| Kim, KY | 1 |
| Ryu, S | 1 |
| Han, S | 1 |
| Shin, BS | 1 |
| Kim, GS | 1 |
| Gwak, MS | 1 |
| Ko, JS | 1 |
| Ochmann, C | 1 |
| Tuschy, B | 1 |
| Beschmann, R | 1 |
| Hamm, F | 1 |
| Röhm, KD | 1 |
| Piper, SN | 1 |
| Feng, J | 1 |
| Zuo, Z | 1 |
| Fortune, B | 1 |
| Cull, G | 1 |
| Wang, L | 1 |
| Van Buskirk, EM | 1 |
| Cioffi, GA | 1 |
| Recio-Pinto, E | 1 |
| Nikonorov, IM | 1 |
| Blanck, TJ | 1 |
| Lee, HT | 1 |
| Emala, CW | 1 |
| Steele, EC | 1 |
| Guo, Q | 1 |
| Namura, S | 1 |
| Simpson, JI | 1 |
| Eide, TR | 1 |
| Schiff, GA | 1 |
| Clagnaz, JF | 1 |
| Zisbrod, Z | 1 |
| Newman, SB | 1 |
| Hossain, I | 1 |
| Imai, M | 1 |
| Kon, S | 1 |
| Inaba, H | 1 |
| Koivusalo, AM | 1 |
| Scheinin, M | 1 |
| Tikkanen, I | 1 |
| Yli-Suomu, T | 1 |
| Ristkari, S | 1 |
| Laakso, J | 1 |
| Lindgren, L | 1 |
| Shime, N | 1 |
| Fukui, M | 1 |
| Yoshioka, M | 1 |
| Sekimoto, M | 1 |
| Tojo, H | 1 |
| Tanaka, Y | 1 |
| Li, F | 1 |
| Hayes, JK | 1 |
| Wong, KC | 1 |
| Szakacs, J | 1 |
| Rice, MJ | 1 |
| Hjelmhaug, JA | 1 |
| Southard, JH | 1 |
3 trials available for isoflurane and Ischemia
| Article | Year |
|---|---|
Extracellular vesicles isolated from patients undergoing remote ischemic preconditioning decrease hypoxia-evoked apoptosis of cardiomyoblasts after isoflurane but not propofol exposure.
Topics: Aged; Anesthesia; Animals; Apoptosis; Coronary Artery Bypass; Extracellular Vesicles; Female; Humans | 2020 |
Supplemental oxygen reduces serotonin levels in plasma and platelets during colorectal surgery and reduces postoperative nausea and vomiting.
Topics: Aged; Aged, 80 and over; Anesthetics, Inhalation; Blood Gas Analysis; Chromatography, High Pressure | 2010 |
Effects of esmolol on haemodynamic response to CO2 pneumoperitoneum for laparoscopic surgery.
Topics: Acetylglucosaminidase; Adrenergic beta-Agonists; Adult; Alfentanil; Anesthetics, Inhalation; Anesthe | 1998 |
15 other studies available for isoflurane and Ischemia
| Article | Year |
|---|---|
Protective Effect of Oxygen and Isoflurane in Rodent Model of Intestinal Ischemia-Reperfusion Injury.
Topics: Anesthetics, Inhalation; Animals; Ischemia; Isoflurane; Male; Oxygen; Rats; Rats, Sprague-Dawley; Re | 2023 |
Isoflurane Anesthesia's Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model.
Topics: Anesthesia; Animals; Brain; Disease Models, Animal; Gene Expression; Gene Expression Regulation; Isc | 2023 |
Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Apoptosis; Cell Survival; Cyclosporine; | 2017 |
Isoflurane Preconditioning Alleviated Murine Liver Ischemia and Reperfusion Injury by Restoring AMPK/mTOR-Mediated Autophagy.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Ischemia; Ischemic Preconditioning; Isoflurane; L | 2017 |
Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats.
Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Ischemia; Ischemic Precond | 2017 |
Isoflurane preconditioning increases endothelial cell tolerance to in-vitro simulated ischaemia.
Topics: Anesthetics, Inhalation; Animals; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothe | 2011 |
Factors affecting the use of multifocal electroretinography to monitor function in a primate model of glaucoma.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Local; Animals; Electroretinography; Glau | 2002 |
G-protein activation decreases the isoflurane inhibition of N-type Ca2+ currents. An increase in the isoflurane blocking potency of N-type Ca2+ currents may contribute to the known neuroprotection action of isoflurane during ischemia.
Topics: Anesthetics, Inhalation; Calcium Channel Blockers; Calcium Channels, N-Type; Cell Line; Chloride Cha | 2004 |
Renal protection with isoflurane.
Topics: Anesthetics, Inhalation; Animals; Extracellular Signal-Regulated MAP Kinases; Ischemia; Isoflurane; | 2006 |
Filamentous middle cerebral artery occlusion causes ischemic damage to the retina in mice.
Topics: Amaurosis Fugax; Animals; Apoptosis; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; | 2008 |
Isoflurane versus sodium nitroprusside for the control of proximal hypertension during thoracic aortic cross-clamping: effects on spinal cord ischemia.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Constriction; Dogs; Hemodynamics; Hypertension; I | 1995 |
Effects of halothane, isoflurane and sevoflurane on ischemia-reperfusion injury in the perfused liver of fasted rats.
Topics: Anesthetics, Inhalation; Animals; Ethers; Halothane; Ischemia; Isoflurane; L-Lactate Dehydrogenase; | 1996 |
[Assessment of oxygen transport in individual splanchnic organs using critical oxygen extraction].
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Digestive System; Dogs; Ischemia; Isoflura | 1999 |
Administration of sevoflurane and isoflurane prior to prolonged global ischemia improves heart function in isolated rat heart.
Topics: Anesthetics, Inhalation; Animals; In Vitro Techniques; Ischemia; Ischemic Preconditioning, Myocardia | 2000 |
The effect of halothane, isoflurane, and verapamil on ischemic-isolated rabbit renal tubules.
Topics: Adenosine Triphosphate; Animals; Halothane; In Vitro Techniques; Intracellular Membranes; Ischemia; | 1989 |