isoflurane has been researched along with Innate Inflammatory Response in 77 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isoflurane induced significant neuro-inflammation and oxidative stress in the microglia cells." | 8.31 | Knockdown of lncRNA BDNF-AS alleviates isoflurane-induced neuro-inflammation and cognitive dysfunction through modulating miR-214-3p. ( Jin, Y; Lu, Y; Mao, Y; Wang, L; Yuan, Y, 2023) |
| " Compared to isoflurane anesthesia, propofol anesthesia exhibited less effect on spatial learning and memory of rats with cardiac surgery and contributed to a relative reduction in activated microglia in the hippocampus, a notable increase in miR-223-3p expression, and a decrease in inflammation." | 8.12 | Propofol alleviates postoperative cognitive dysfunction by inhibiting inflammation via up-regulating miR-223-3p in aged rats. ( Cao, C; Deng, F; Lian, F; Liu, C; Zhou, Z, 2022) |
| "Isoflurane (ISO) has been widely used in clinical anesthesia, and exposure to ISO leads to cognitive dysfunction." | 8.12 | MiR-128-3p Attenuates the Neurotoxicity in Rats Induced by Isoflurane Anesthesia. ( Dai, S; Qian, D; Sun, Y; Wang, L; Yuan, Y, 2022) |
| "Agomelatine might attenuate isoflurane-induced inflammation and damage via down-regulating Egr-1 in brain endothelial cells." | 7.96 | Agomelatine Attenuates Isoflurane-Induced Inflammation and Damage in Brain Endothelial Cells. ( Chang, H; Cheng, F; Liu, J; Liu, Y; Yan, F; Yang, A, 2020) |
| " The aim of the present study was to determine the role of HIF‑1α in isoflurane‑induced neuroinflammation and the resulting cognitive impairment." | 7.88 | Isoflurane‑induced postoperative cognitive dysfunction is mediated by hypoxia‑inducible factor‑1α‑dependent neuroinflammation in aged rats. ( Cao, Y; Guo, X; Li, L; Li, Z; Ma, L; Ni, C; Shi, C; Yang, N, 2018) |
| "The effects of combined therapy with isoflurane and oxygen on lung injury and sepsis were determined in animal models of sepsis induced by cecal ligation and puncture (CLP) or intraperitoneal injection of lipopolysaccharide (LPS) or zymosan." | 7.85 | Sub-anesthesia Dose of Isoflurane in 60% Oxygen Reduces Inflammatory Responses in Experimental Sepsis Models. ( Dong, HL; Han, H; Hou, LC; Hou, ZX; Huang, Y; Pu, ZS; Shao, T; Sun, DD; Wang, XX; Xiong, LZ; Yang, WW; Zhang, EF; Zhang, ZX, 2017) |
| "These results suggest that ginsenoside Rb1 may attenuate the isoflurane/surgery-induced cognitive impairment by inhibiting neuroinflammation and oxidative stress pending future studies." | 7.85 | Ginsenoside Rb1 Attenuates Isoflurane/surgery-induced Cognitive Dysfunction via Inhibiting Neuroinflammation and Oxidative Stress. ( Ding, GN; Dong, P; Hong, FX; Miao, HH; Tian, M; Zhang, Y, 2017) |
| "Compared with isoflurane, sevoflurane did not affect lung inflammation in ARDSexp, but it did reduce lung inflammation in ARDSp." | 7.85 | Sevoflurane, Compared With Isoflurane, Minimizes Lung Damage in Pulmonary but Not in Extrapulmonary Acute Respiratory Distress Syndrome in Rats. ( Araújo, MN; Cavalcanti, VCM; Cruz, FF; Felix, NS; Fernandes, FC; Heil, LBB; Morales, MM; Pelosi, P; Rocco, PRM; Samary, CS; Santos, CL; Silva, JD; Silva, PL; Villela, NR, 2017) |
| "This study investigated the role of glycogen synthase kinase-3β (GSK-3β) in isoflurane-induced neuroinflammation and cognitive dysfunction in aged rats." | 7.79 | Role of GSK-3β in isoflurane-induced neuroinflammation and cognitive dysfunction in aged rats. ( Chen, X; Chen, YL; Li, SY; Luo, AL; Tan, L; Wang, JT; Xiang, Q; Zhao, YL, 2013) |
| "4% isoflurane (ISO) on the development of inflammation and apoptosis caused by zymosan (ZY) in mice." | 7.79 | Anesthetic isoflurane posttreatment attenuates experimental lung injury by inhibiting inflammation and apoptosis. ( Chen, HJ; Gao, CF; Hou, LC; Li, JT; Li, NL; Li, W; Liu, X; Mu, JL; Wang, H; Wang, LF; Xie, KL, 2013) |
| " To evaluate the influence of the inflammatory process, we studied in the same patient the sufentanil requirement during procedures that occur during two distinct phases of ulcerative colitis with different inflammatory profiles: (1) left colectomy for major colitis unresponsive to medical treatment during acute inflammation and (2) coloprotectomy with ileoanal anastomosis, three months after recovery of the acute inflammatory episode." | 7.74 | Inflammation affects sufentanil consumption in ulcerative colitis. ( Colombel, JF; Dusson, C; Fleyfel, M; Gambiez, L; Guidat, A; Ousmane, ML; Vallet, B, 2008) |
| "Previous studies have indicated that volatile anesthetic pretreatment protects cells from inflammation; therefore, the authors hypothesized that pretreatment with isoflurane may attenuate the hemodynamic and pathologic changes to the vasculature that are associated with inflammation." | 7.72 | Isoflurane pretreatment inhibits lipopolysaccharide-induced inflammation in rats. ( Cerilli, LA; Hayes, JK; Plachinta, RV; Rich, GF, 2003) |
| "Isoflurane pretreatment supported hemodynamics and increased leukocyte rolling velocities in the mesenteric microcirculation during lipopolysaccharide-induced inflammation." | 7.72 | Isoflurane pretreatment supports hemodynamics and leukocyte rolling velocities in rat mesentery during lipopolysaccharide-induced inflammation. ( Havaleshko, DM; Hayes, JK; Plachinta, RV; Rich, GF, 2004) |
| "Isoflurane can significantly induce inflammation in children without surgical stress." | 5.51 | The role and mechanism of TLR4-siRNA in the impairment of learning and memory in young mice induced by isoflurane. ( Chen, D; Feng, Y; Lin, L; Liu, Y; Luo, H; Yu, X; Zhong, W, 2022) |
| "A brief (approximately 60 min) exposure to isoflurane general anesthesia, without induced surgical stress, significantly increased serum IL-1β, a selective activation marker of systemic inflammation (IL-1β pathway)." | 5.24 | Selective induction of IL-1β after a brief isoflurane anesthetic in children undergoing MRI examination. ( Bissonnette, B; Christofi, FL; Quinn, KM; Tobias, JD; Whitaker, EE; Wiemann, BZ; Xia, JC, 2017) |
| "Isoflurane induced significant neuro-inflammation and oxidative stress in the microglia cells." | 4.31 | Knockdown of lncRNA BDNF-AS alleviates isoflurane-induced neuro-inflammation and cognitive dysfunction through modulating miR-214-3p. ( Jin, Y; Lu, Y; Mao, Y; Wang, L; Yuan, Y, 2023) |
| "In this study, the effects of exposure to isoflurane, sevoflurane and desflurane on the oxidative response and inflammation at different times was analyzed in the lungs of adult C57BL/6 mice." | 4.12 | The deleterious impact of exposure to different inhaled anesthetics is time dependent. ( Bezerra, FS; Cangussú, SD; Castro, TF; de Souza, ABF; Machado-Junior, PA; Perucci, LO; Talvani, A, 2022) |
| " Compared to isoflurane anesthesia, propofol anesthesia exhibited less effect on spatial learning and memory of rats with cardiac surgery and contributed to a relative reduction in activated microglia in the hippocampus, a notable increase in miR-223-3p expression, and a decrease in inflammation." | 4.12 | Propofol alleviates postoperative cognitive dysfunction by inhibiting inflammation via up-regulating miR-223-3p in aged rats. ( Cao, C; Deng, F; Lian, F; Liu, C; Zhou, Z, 2022) |
| "Isoflurane (ISO) has been widely used in clinical anesthesia, and exposure to ISO leads to cognitive dysfunction." | 4.12 | MiR-128-3p Attenuates the Neurotoxicity in Rats Induced by Isoflurane Anesthesia. ( Dai, S; Qian, D; Sun, Y; Wang, L; Yuan, Y, 2022) |
| " The exposed group was constituted by anesthesia providers who were mainly exposed to the anesthetics sevoflurane and isoflurane (10 ppm) and to a lesser degree to nitrous oxide (150 ppm), and the control group was constituted by physicians who had no exposure to WAGs." | 4.02 | Oxidative stress, DNA damage, inflammation and gene expression in occupationally exposed university hospital anesthesia providers. ( Arruda, NM; Aun, AG; Braz, JRC; Braz, LG; Braz, MG; Chen, CY; Corrêa, CR; de Carvalho, LR; De Vivo, I; Figueiredo, DBS; Lara, JR; Nogueira, FR; Silva, MAP; Souza, KM, 2021) |
| "DUSP14 may effectively protect against isoflurane-induced neuro-inflammation, brain damage and cognitive dysfunction, indicating that DUSP14 may be a potential predictor and therapeutic target for POCD." | 3.96 | Neuroprotective effect of DUSP14 overexpression against isoflurane-induced inflammatory response, pyroptosis and cognitive impairment in aged rats through inhibiting the NLRP3 inflammasome. ( Peng, J; Que, YY; Zhang, FX; Zhu, T, 2020) |
| "Agomelatine might attenuate isoflurane-induced inflammation and damage via down-regulating Egr-1 in brain endothelial cells." | 3.96 | Agomelatine Attenuates Isoflurane-Induced Inflammation and Damage in Brain Endothelial Cells. ( Chang, H; Cheng, F; Liu, J; Liu, Y; Yan, F; Yang, A, 2020) |
| "We compared 6 frequently used mouse blood-sampling methods (lateral tail incision; tail-tip amputation; sublingual, submandibular, and saphenous vein puncture; and retrobulbar sinus puncture during isoflurane anesthesia) with regard to induction of local and systemic inflammation, stomach contents, weight changes, and corticosterone levels at 6 h to 12 d after sampling." | 3.91 | Time-dependent Pathologic and Inflammatory Consequences of Various Blood Sampling Techniques in Mice. ( Andersen, KH; Frøkiaer, H; Jensen, HE; Jensen, LK; Metzdorff, SB; Sørensen, DB; Teilmann, AC, 2019) |
| " The purpose of this study was to better understand the effect of inflammation on cerebral subcellular energetics in animals exposed to two different anesthetic agents-a GABA agonist (propofol) and a volatile agent (isoflurane)." | 3.91 | Impact of inflammation on brain subcellular energetics in anesthetized rats. ( Ikeda, K; Osuru, HP; Paila, U; Thiele, RH; Zuo, Z, 2019) |
| " The aim of the present study was to determine the role of HIF‑1α in isoflurane‑induced neuroinflammation and the resulting cognitive impairment." | 3.88 | Isoflurane‑induced postoperative cognitive dysfunction is mediated by hypoxia‑inducible factor‑1α‑dependent neuroinflammation in aged rats. ( Cao, Y; Guo, X; Li, L; Li, Z; Ma, L; Ni, C; Shi, C; Yang, N, 2018) |
| " Isoflurane induced cognitive impairment and hippocampal inflammation in aged mice but not in young mice." | 3.88 | Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment. ( Cao, L; Chen, Y; Meng, S; Peng, S; Wang, Z; Zuo, Z, 2018) |
| "The effects of combined therapy with isoflurane and oxygen on lung injury and sepsis were determined in animal models of sepsis induced by cecal ligation and puncture (CLP) or intraperitoneal injection of lipopolysaccharide (LPS) or zymosan." | 3.85 | Sub-anesthesia Dose of Isoflurane in 60% Oxygen Reduces Inflammatory Responses in Experimental Sepsis Models. ( Dong, HL; Han, H; Hou, LC; Hou, ZX; Huang, Y; Pu, ZS; Shao, T; Sun, DD; Wang, XX; Xiong, LZ; Yang, WW; Zhang, EF; Zhang, ZX, 2017) |
| "These results suggest that ginsenoside Rb1 may attenuate the isoflurane/surgery-induced cognitive impairment by inhibiting neuroinflammation and oxidative stress pending future studies." | 3.85 | Ginsenoside Rb1 Attenuates Isoflurane/surgery-induced Cognitive Dysfunction via Inhibiting Neuroinflammation and Oxidative Stress. ( Ding, GN; Dong, P; Hong, FX; Miao, HH; Tian, M; Zhang, Y, 2017) |
| "Compared with isoflurane, sevoflurane did not affect lung inflammation in ARDSexp, but it did reduce lung inflammation in ARDSp." | 3.85 | Sevoflurane, Compared With Isoflurane, Minimizes Lung Damage in Pulmonary but Not in Extrapulmonary Acute Respiratory Distress Syndrome in Rats. ( Araújo, MN; Cavalcanti, VCM; Cruz, FF; Felix, NS; Fernandes, FC; Heil, LBB; Morales, MM; Pelosi, P; Rocco, PRM; Samary, CS; Santos, CL; Silva, JD; Silva, PL; Villela, NR, 2017) |
| " In contrast to ketamine/xylazine, this represents a more physiological, translatable strategy for suppression of cardiomyocyte (18)F-FDG uptake when targeting myocardial inflammation." | 3.81 | Clinically relevant strategies for lowering cardiomyocyte glucose uptake for 18F-FDG imaging of myocardial inflammation in mice. ( Bankstahl, JP; Bengel, FM; Thackeray, JT; Wang, Y; Wollert, KC, 2015) |
| "Our results confirm the clinical experience that desflurane is more irritating than isoflurane at equal anesthetic gas concentration, whereas sevoflurane does not activate tracheobronchial sensory nerves to release neuropeptides and induce neurogenic inflammation." | 3.81 | Irritant volatile anesthetics induce neurogenic inflammation through TRPA1 and TRPV1 channels in the isolated mouse trachea. ( Kichko, TI; Leffler, A; Niedermirtl, F; Reeh, PW, 2015) |
| " Isoflurane is a widely used halogenated volatile anesthetic during the perioperative period and protects against endothelial cell death and inflammation." | 3.80 | The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release. ( Brown, KM; Ham, A; Kim, KY; Kim, M; Lee, HT, 2014) |
| "Mice (N = 12 per treatment group) were exposed to anesthetic concentrations of desflurane, isoflurane, and sevoflurane either during induction of sepsis or when the mice showed pronounced symptoms of inflammation." | 3.79 | Volatile anesthetics improve survival after cecal ligation and puncture. ( Beck-Schimmer, B; Castellon, M; Hasler, M; Herrmann, IK; Hu, G; Minshall, RD; Schwartz, DE; Urner, M, 2013) |
| "This study investigated the role of glycogen synthase kinase-3β (GSK-3β) in isoflurane-induced neuroinflammation and cognitive dysfunction in aged rats." | 3.79 | Role of GSK-3β in isoflurane-induced neuroinflammation and cognitive dysfunction in aged rats. ( Chen, X; Chen, YL; Li, SY; Luo, AL; Tan, L; Wang, JT; Xiang, Q; Zhao, YL, 2013) |
| "4% isoflurane (ISO) on the development of inflammation and apoptosis caused by zymosan (ZY) in mice." | 3.79 | Anesthetic isoflurane posttreatment attenuates experimental lung injury by inhibiting inflammation and apoptosis. ( Chen, HJ; Gao, CF; Hou, LC; Li, JT; Li, NL; Li, W; Liu, X; Mu, JL; Wang, H; Wang, LF; Xie, KL, 2013) |
| "5h) revealed anesthesia associated IFNγ-expression and lymphocyte activation which were not observed when animals were treated with ketamine/xylazine (p<0." | 3.78 | Inflammatory immune responses in a reproducible mouse brain death model. ( Floerchinger, B; Ge, X; Jurisch, A; Lee, YL; Schmid, C; Timsit, MO; Tullius, SG; Yuan, X, 2012) |
| " Isoflurane (ISO), ketamine-xylazine (KX), or pentobarbital (PEN) with or without buprenorphine were administered before scald-burn in 72 rats that were euthanized without anesthesia by decapitation after 24 h and compared with unburned shams." | 3.76 | Impact of anesthesia, analgesia, and euthanasia technique on the inflammatory cytokine profile in a rodent model of severe burn injury. ( Al-Mousawi, AM; Branski, LK; Herndon, DN; Jeschke, MG; Kraft, R; Kulp, GA; Mecott, GA; Williams, FN, 2010) |
| "Isoflurane preconditioning exerts its anti-inflammatory activity through the HO-1 pathway in an in vitro inflammation model." | 3.75 | Heme oxygenase-1 mediates the anti-inflammatory effect of isoflurane preconditioning in LPS-stimulated macrophages. ( Jiang, H; Li, QF; Sun, Y; Xu, H; Zhu, YS, 2009) |
| "Using murine peritonitis induced by zymosan and a systems approach, we report that lidocaine delayed and blocked key events in resolution of inflammation." | 3.74 | Anesthetics impact the resolution of inflammation. ( Chiang, N; Fredman, G; Gelman, S; Kasuga, K; Schwab, JM; Serhan, CN, 2008) |
| " To evaluate the influence of the inflammatory process, we studied in the same patient the sufentanil requirement during procedures that occur during two distinct phases of ulcerative colitis with different inflammatory profiles: (1) left colectomy for major colitis unresponsive to medical treatment during acute inflammation and (2) coloprotectomy with ileoanal anastomosis, three months after recovery of the acute inflammatory episode." | 3.74 | Inflammation affects sufentanil consumption in ulcerative colitis. ( Colombel, JF; Dusson, C; Fleyfel, M; Gambiez, L; Guidat, A; Ousmane, ML; Vallet, B, 2008) |
| "Adult and neonatal rat ventricular myocytes and atrial HL-1 myocytes were exposed to hypoxia, hydrogen peroxide, or neutrophils with or without isoflurane pretreatment." | 3.73 | Isoflurane inhibits cardiac myocyte apoptosis during oxidative and inflammatory stress by activating Akt and enhancing Bcl-2 expression. ( Bienengraeber, MW; Bosnjak, ZJ; Jamnicki-Abegg, M; Kersten, JR; Pagel, PS; Warltier, DC; Weihrauch, D, 2005) |
| "Previous studies have indicated that volatile anesthetic pretreatment protects cells from inflammation; therefore, the authors hypothesized that pretreatment with isoflurane may attenuate the hemodynamic and pathologic changes to the vasculature that are associated with inflammation." | 3.72 | Isoflurane pretreatment inhibits lipopolysaccharide-induced inflammation in rats. ( Cerilli, LA; Hayes, JK; Plachinta, RV; Rich, GF, 2003) |
| "Isoflurane pretreatment supported hemodynamics and increased leukocyte rolling velocities in the mesenteric microcirculation during lipopolysaccharide-induced inflammation." | 3.72 | Isoflurane pretreatment supports hemodynamics and leukocyte rolling velocities in rat mesentery during lipopolysaccharide-induced inflammation. ( Havaleshko, DM; Hayes, JK; Plachinta, RV; Rich, GF, 2004) |
| "Prevention of epilepsy is a great unmet need." | 2.66 | Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy? ( Bar-Klein, G; Friedman, A; Hameed, MQ; Jozwiak, S; Kaminski, RM; Klein, P; Klitgaard, H; Koepp, M; Löscher, W; Prince, DA; Rotenberg, A; Twyman, R; Vezzani, A; Wong, M, 2020) |
| "Maprotiline is a novel drug that has been licensed as an antidepressant with considerable anti-inflammatory activity." | 1.62 | Maprotiline ameliorates isoflurane-induced microglial activation via regulating triggering receptor expressed in myeloid cells 2 (TREM2). ( Chen, Z; He, Y; Hu, R, 2021) |
| "Isoflurane is a widely used anesthetic agent, which is associated with the development of POCD; however, the precise mechanisms remain unclear." | 1.56 | Effects of PYRIN-containing Apaf1-like protein 1 on isoflurane-induced postoperative cognitive dysfunction in aged rats. ( Fan, X; Li, F; Qiu, J; Zhang, X; Zhang, Y, 2020) |
| "Vitexin is a bioactive compound extracted from hawthorn leaves, which reduces blood pressure and has anti‑inflammatory and potential anticancer effects." | 1.43 | Neuroprotective effects of vitexin against isoflurane-induced neurotoxicity by targeting the TRPV1 and NR2B signaling pathways. ( Chen, L; Shan, S; Zhang, B; Zhao, X, 2016) |
| "Chronic migraine (CM) is often associated with chronic tenderness of pericranial muscles." | 1.43 | Upregulation of inflammatory gene transcripts in periosteum of chronic migraineurs: Implications for extracranial origin of headache. ( Bhasin, MK; Blake, P; Buettner, C; Burstein, R; Papavassiliou, E; Perry, CJ; Schain, AJ, 2016) |
| "When isoflurane was administered during kainate injection, duration and severity of SE were not affected, but only few rats developed spontaneous recurrent seizures." | 1.43 | Isoflurane prevents acquired epilepsy in rat models of temporal lobe epilepsy. ( Bankstahl, JP; Bankstahl, M; Bar-Klein, G; Bascuñana, P; Brandt, C; Dalipaj, H; Friedman, A; Klee, R; Löscher, W; Töllner, K, 2016) |
| "Ninety cancer patients with selective operation from March 2011 to May 2014 were randomly divided into group A (34 cases), group B (28 cases) and group C (28 cases)." | 1.40 | Influence of propofol, isoflurane and enflurance on levels of serum interleukin-8 and interleukin-10 in cancer patients. ( Liu, TC, 2014) |
| "The pentobarbital effect was significant within 3 days of surgery and persisted through the remainder of the testing period." | 1.37 | Deleterious impact of a γ-aminobutyric acid type A receptor preferring general anesthetic when used in the presence of persistent inflammation. ( Boegel, K; Gold, MS; Gyulai, FE; Moore, KK, 2011) |
| "Paw inflammation was induced with 3% carrageenan and was measured with a plethysmometer at 30 minutes and 4, 8, and 24 hours after intraperitoneal injection." | 1.36 | Evaluation of the anti-inflammatory effects of ellagic acid. ( Corbett, S; Daniel, J; Drayton, R; Field, M; Garrett, N; Steinhardt, R, 2010) |
| "Nitrous oxide is a widely used anesthetic gas." | 1.35 | Inflammatory response to nitrous oxide in the central nervous system. ( Baethmann, A; Lehmberg, J; Uhl, E; Waldner, M, 2008) |
| "Sevoflurane is a specific activator of the apoptosis signal-regulating kinase-1-, MKK3/MKK6-p38 MAP kinase cascade in Jurkat T-cells." | 1.35 | Sevoflurane-mediated activation of p38-mitogen-activated stresskinase is independent of apoptosis in Jurkat T-cells. ( Auwaerter, V; Frick, M; Geiger, KK; Goebel, U; Humar, M; Loop, T; Pahl, HL; Pannen, BH; Roesslein, M; Schwer, C, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 13 (16.88) | 29.6817 |
| 2010's | 46 (59.74) | 24.3611 |
| 2020's | 18 (23.38) | 2.80 |
| Authors | Studies |
|---|---|
| Matta, JA | 1 |
| Cornett, PM | 1 |
| Miyares, RL | 1 |
| Abe, K | 1 |
| Sahibzada, N | 1 |
| Ahern, GP | 1 |
| Hu, R | 1 |
| He, Y | 3 |
| Chen, Z | 3 |
| Lian, F | 1 |
| Cao, C | 1 |
| Deng, F | 1 |
| Liu, C | 3 |
| Zhou, Z | 3 |
| Lin, L | 4 |
| Chen, D | 6 |
| Yu, X | 3 |
| Zhong, W | 1 |
| Liu, Y | 9 |
| Feng, Y | 1 |
| Luo, H | 1 |
| Qian, D | 1 |
| Dai, S | 1 |
| Sun, Y | 6 |
| Yuan, Y | 3 |
| Wang, L | 9 |
| Yılmaz, H | 1 |
| Şengelen, A | 1 |
| Demirgan, S | 1 |
| Paşaoğlu, HE | 1 |
| Çağatay, M | 1 |
| Erman, İE | 1 |
| Bay, M | 1 |
| Güneyli, HC | 1 |
| Önay-Uçar, E | 1 |
| Machado-Junior, PA | 1 |
| de Souza, ABF | 1 |
| Castro, TF | 1 |
| Perucci, LO | 1 |
| Talvani, A | 1 |
| Cangussú, SD | 1 |
| Bezerra, FS | 1 |
| Huang, X | 3 |
| Su, Z | 1 |
| Zhang, S | 3 |
| Xu, X | 3 |
| Yang, B | 2 |
| Mao, Y | 1 |
| Lu, Y | 3 |
| Jin, Y | 1 |
| Rossi, H | 1 |
| Raekallio, M | 1 |
| Määttä, M | 1 |
| Tapio, H | 1 |
| Hanifeh, M | 1 |
| Junnila, J | 1 |
| Rajamäki, MM | 1 |
| Mykkänen, A | 1 |
| Guo, X | 3 |
| Deng, J | 1 |
| Zheng, B | 1 |
| Liu, H | 5 |
| Zhang, Y | 9 |
| Ying, Y | 1 |
| Jia, J | 1 |
| Ruan, X | 1 |
| Klein, P | 1 |
| Friedman, A | 2 |
| Hameed, MQ | 1 |
| Kaminski, RM | 1 |
| Bar-Klein, G | 2 |
| Klitgaard, H | 1 |
| Koepp, M | 1 |
| Jozwiak, S | 1 |
| Prince, DA | 1 |
| Rotenberg, A | 1 |
| Twyman, R | 1 |
| Vezzani, A | 1 |
| Wong, M | 1 |
| Löscher, W | 2 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 6 |
| Huang, L | 2 |
| Hu, K | 1 |
| Wang, H | 6 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 5 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 5 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 6 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 2 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 2 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Liu, Z | 4 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 8 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 3 |
| Yang, X | 1 |
| Li, W | 4 |
| Wang, T | 5 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Gut Microbiome and Blood Indices in Patients With AD and Their Spousal Caregivers[NCT05601856] | 104 participants (Anticipated) | Observational | 2022-12-15 | Recruiting | |||
| Neuroplasticity Induced by General Anaesthesia[NCT04125121] | 20 participants (Actual) | Interventional | 2019-09-26 | Completed | |||
| Phase 1 Study of Antiinflammatory Effect of Sevoflurane in Open Lung Surgery With One-Lung Ventilation[NCT02188407] | Phase 1 | 40 participants (Actual) | Interventional | 2008-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for isoflurane and Innate Inflammatory Response
| Article | Year |
|---|---|
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Atorvastatin; Brain Injuries, Traumatic; Cef | 2020 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Impact of Volatile Anesthetics on Oxidative Stress and Inflammation.
Topics: Anesthetics; Antioxidants; DNA Damage; Humans; Inflammation; Isoflurane; Methyl Ethers; Oxidative St | 2015 |
7 trials available for isoflurane and Innate Inflammatory Response
| Article | Year |
|---|---|
The role and mechanism of TLR4-siRNA in the impairment of learning and memory in young mice induced by isoflurane.
Topics: Animals; Brain-Derived Neurotrophic Factor; Inflammation; Interleukin-6; Isoflurane; Mice; RNA, Smal | 2022 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Comparison of the effects of desflurane and propofol anesthesia on the inflammatory response and s100β protein during coronary artery bypass grafting.
Topics: Adult; Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Cardiotonic Agents; Cent | 2013 |
Selective induction of IL-1β after a brief isoflurane anesthetic in children undergoing MRI examination.
Topics: Anesthesia, General; Anesthetics, Inhalation; Child; Child, Preschool; Cytokines; Female; Humans; In | 2017 |
Effects of volatile and intravenous anesthesia on the alveolar and systemic inflammatory response in thoracic surgical patients.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous | 2011 |
Effects of volatile and intravenous anesthesia on the alveolar and systemic inflammatory response in thoracic surgical patients.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous | 2011 |
Effects of volatile and intravenous anesthesia on the alveolar and systemic inflammatory response in thoracic surgical patients.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous | 2011 |
Effects of volatile and intravenous anesthesia on the alveolar and systemic inflammatory response in thoracic surgical patients.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous | 2011 |
Evaluation of inflammatory and hemostatic surgical stress responses in male cats after castration under general anesthesia with or without local anesthesia.
Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Animals; Cats; I | 2012 |
The effects of propofol on lipid peroxidation and inflammatory response in elective coronary artery bypass grafting.
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Anti-Inflammatory Agents; Coronary Artery B | 2004 |
68 other studies available for isoflurane and Innate Inflammatory Response
| Article | Year |
|---|---|
General anesthetics activate a nociceptive ion channel to enhance pain and inflammation.
Topics: Anesthetics, General; Animals; Ankyrins; Calcium Channels; Humans; Inflammation; Isoflurane; Mice; P | 2008 |
Maprotiline ameliorates isoflurane-induced microglial activation via regulating triggering receptor expressed in myeloid cells 2 (TREM2).
Topics: Animals; Biomarkers; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Inflammation; I | 2021 |
Propofol alleviates postoperative cognitive dysfunction by inhibiting inflammation via up-regulating miR-223-3p in aged rats.
Topics: Animals; Cognitive Dysfunction; Humans; Inflammation; Isoflurane; MicroRNAs; Postoperative Cognitive | 2022 |
MiR-128-3p Attenuates the Neurotoxicity in Rats Induced by Isoflurane Anesthesia.
Topics: Anesthesia; Animals; Apoptosis; Inflammation; Isoflurane; MicroRNAs; Neurotoxicity Syndromes; Rats; | 2022 |
Acutely increased aquaporin-4 exhibits more potent protective effects in the cortex against single and repeated isoflurane-induced neurotoxicity in the developing rat brain.
Topics: Animals; Animals, Newborn; Apoptosis; Aquaporin 4; Brain; Hippocampus; Inflammation; Isoflurane; Rat | 2023 |
The deleterious impact of exposure to different inhaled anesthetics is time dependent.
Topics: Anesthetics, Inhalation; Animals; Catalase; Desflurane; Inflammation; Isoflurane; Methyl Ethers; Mic | 2022 |
ANGPTL2 Deletion Attenuates Neuroinflammation and Cognitive Dysfunction Induced by Isoflurane in Aged Mice through Modulating MAPK Pathway.
Topics: Angiopoietin-Like Protein 2; Animals; Cognitive Dysfunction; Inflammation; Isoflurane; Mice; Neuroin | 2023 |
Knockdown of lncRNA BDNF-AS alleviates isoflurane-induced neuro-inflammation and cognitive dysfunction through modulating miR-214-3p.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Inflammation; Isoflurane; MicroRN | 2023 |
Effects of general anaesthesia in dorsal recumbency with and without vatinoxan on bronchoalveolar lavage cytology of healthy horses.
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Cross-Over Stud | 2019 |
HDAC1 and HDAC2 regulate anti-inflammatory effects of anesthetic isoflurane in human monocytes.
Topics: Anesthetics, Inhalation; Cell Line; Gene Silencing; Histone Deacetylase 1; Histone Deacetylase 2; Hi | 2020 |
Neuroprotective effects of isoflurane against lipopolysaccharide-induced neuroinflammation in BV2 microglial cells by regulating HMGB1/TLRs pathway.
Topics: Animals; Cell Line; Cell Survival; HMGB1 Protein; Inflammation; Isoflurane; Lipopolysaccharides; Mic | 2020 |
Effects of PYRIN-containing Apaf1-like protein 1 on isoflurane-induced postoperative cognitive dysfunction in aged rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Disease Models, Animal; Gene Silencing; Hippocampus; Inflam | 2020 |
Neuroprotective effect of DUSP14 overexpression against isoflurane-induced inflammatory response, pyroptosis and cognitive impairment in aged rats through inhibiting the NLRP3 inflammasome.
Topics: Aging; Animals; Cognitive Dysfunction; Dual-Specificity Phosphatases; Inflammasomes; Inflammation; I | 2020 |
The differential effects of isoflurane and sevoflurane on neonatal mice.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Behavior, Animal; Brain; Female; Infl | 2020 |
Oxidative stress, DNA damage, inflammation and gene expression in occupationally exposed university hospital anesthesia providers.
Topics: Adult; Aged; Air Pollutants, Occupational; Anesthesia; Anesthetics, Inhalation; Antioxidants; DNA Da | 2021 |
Isoflurane reduces septic neuron injury by HO‑1‑mediated abatement of inflammation and apoptosis.
Topics: Animals; Apoptosis; Disease Models, Animal; Heme Oxygenase-1; Inflammation; Isoflurane; Male; Membra | 2021 |
Agomelatine Attenuates Isoflurane-Induced Inflammation and Damage in Brain Endothelial Cells.
Topics: Acetamides; Brain; Cell Survival; Cells, Cultured; Endothelial Cells; Humans; Inflammation; Isoflura | 2020 |
Anesthetics isoflurane and sevoflurane attenuate flagellin-mediated inflammation in the lung.
Topics: Anesthetics, Inhalation; Animals; Cell Line, Tumor; Cystic Fibrosis; Epithelial Cells; Female; Flage | 2021 |
Sub-anesthesia Dose of Isoflurane in 60% Oxygen Reduces Inflammatory Responses in Experimental Sepsis Models.
Topics: Adult; Anesthesia; Animals; Blotting, Western; Bronchoalveolar Lavage Fluid; Disease Models, Animal; | 2017 |
Ginsenoside Rb1 Attenuates Isoflurane/surgery-induced Cognitive Dysfunction via Inhibiting Neuroinflammation and Oxidative Stress.
Topics: Anesthetics, Inhalation; Animals; Cognition; Cognitive Dysfunction; Female; Ginsenosides; Hippocampu | 2017 |
Isoflurane‑induced postoperative cognitive dysfunction is mediated by hypoxia‑inducible factor‑1α‑dependent neuroinflammation in aged rats.
Topics: Anesthetics, Inhalation; Animals; Cognitive Dysfunction; Hippocampus; Hypoxia-Inducible Factor 1, al | 2018 |
Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment.
Topics: Aging; Amino Acid Chloromethyl Ketones; Anesthetics, Inhalation; Animals; Caspase 1; Cell Line, Tran | 2018 |
The influence of anesthetics on substantia nigra tyrosine hydroxylase expression and tau phosphorylation in the hypoxic-ischemic near-term lamb.
Topics: Anesthetics; Animals; Animals, Newborn; Brain Mapping; Dopamine; Dopaminergic Neurons; Female; Gluta | 2018 |
Inflammation caused by peripheral immune cells across into injured mouse blood brain barrier can worsen postoperative cognitive dysfunction induced by isoflurane.
Topics: Animals; Blood-Brain Barrier; CD4-Positive T-Lymphocytes; Cognitive Dysfunction; Disease Models, Ani | 2018 |
Time-dependent Pathologic and Inflammatory Consequences of Various Blood Sampling Techniques in Mice.
Topics: Anesthesia; Anesthetics, Inhalation; Animal Welfare; Animals; Blood Specimen Collection; Corticoster | 2019 |
Callistephin enhances the protective effects of isoflurane on microglial injury through downregulation of inflammation and apoptosis.
Topics: Animals; Anthocyanins; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cell Line; Inflammation; I | 2019 |
Impact of inflammation on brain subcellular energetics in anesthetized rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Brain; Electron Tra | 2019 |
Anesthetic isoflurane posttreatment attenuates experimental lung injury by inhibiting inflammation and apoptosis.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Blotting, Western; Enzyme-Linked Immunosorbent Assay; I | 2013 |
Volatile anesthetics improve survival after cecal ligation and puncture.
Topics: Anesthetics, Inhalation; Animals; Cecum; Desflurane; Disease Models, Animal; Inflammation; Isofluran | 2013 |
Role of GSK-3β in isoflurane-induced neuroinflammation and cognitive dysfunction in aged rats.
Topics: Animals; Cognition Disorders; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Inflammat | 2013 |
Tau hyperphosphorylation: a downstream effector of isoflurane-induced neuroinflammation in aged rodents.
Topics: Age Factors; Alzheimer Disease; Anesthetics, Inhalation; Animals; Cognition Disorders; Cytokines; In | 2014 |
A subanesthetic dose of isoflurane during postconditioning ameliorates zymosan-induced neutrophil inflammation lung injury and mortality in mice.
Topics: Active Transport, Cell Nucleus; Animals; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Chemokine | 2013 |
Intravenous pretreatment with emulsified isoflurane preconditioning protects kidneys against ischemia/reperfusion injury in rats.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Emulsions; Inflammation; Ischemic | 2014 |
Comparison of neurodegeneration and cognitive impairment in neonatal mice exposed to propofol or isoflurane.
Topics: Administration, Inhalation; Anesthetics; Animals; Animals, Newborn; Apoptosis; Brain Damage, Chronic | 2014 |
The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Amides; Anesthetics, Inhalation; Animals; Antigen | 2014 |
Volatile anaesthetics reduce neutrophil inflammatory response by interfering with CXC receptor-2 signalling.
Topics: Adult; Anesthetics, Inhalation; Desflurane; Female; Flow Cytometry; Humans; Inflammation; Isoflurane | 2015 |
Subanesthetic isoflurane reduces zymosan-induced inflammation in murine Kupffer cells by inhibiting ROS-activated p38 MAPK/NF-κB signaling.
Topics: Anesthetics; Animals; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chemokines; Cyclooxyg | 2014 |
Influence of propofol, isoflurane and enflurance on levels of serum interleukin-8 and interleukin-10 in cancer patients.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Enflurane; Female; Humans; Inflammat | 2014 |
Clinically relevant strategies for lowering cardiomyocyte glucose uptake for 18F-FDG imaging of myocardial inflammation in mice.
Topics: Anesthetics, General; Animals; Anticoagulants; Fasting; Fluorodeoxyglucose F18; Glucose; Heparin; In | 2015 |
Laparotomy in mice induces blood cell expression of inflammatory and stress genes.
Topics: Animals; Blood Cells; Gene Expression Profiling; Gene Expression Regulation; Inflammation; Isofluran | 2015 |
Irritant volatile anesthetics induce neurogenic inflammation through TRPA1 and TRPV1 channels in the isolated mouse trachea.
Topics: Anesthetics, Inhalation; Animals; Calcitonin Gene-Related Peptide; Desflurane; Dose-Response Relatio | 2015 |
The choice of general anesthetics may not affect neuroinflammation and impairment of learning and memory after surgery in elderly rats.
Topics: Anesthetics, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Buprenorphine; Cal | 2015 |
Does occupational exposure to anesthetic gases lead to increase of pro-inflammatory cytokines?
Topics: Adult; Anesthetics, Inhalation; Cytokines; Environmental Monitoring; Female; Humans; Inflammation; I | 2015 |
Inflammation Increases Neuronal Sensitivity to General Anesthetics.
Topics: Anesthetics, General; Anesthetics, Inhalation; Animals; Cells, Cultured; Cerebral Cortex; Etomidate; | 2016 |
Upregulation of inflammatory gene transcripts in periosteum of chronic migraineurs: Implications for extracranial origin of headache.
Topics: Adolescent; Adult; Aged; Biomarkers; Case-Control Studies; Cephaloridine; Chronic Disease; Fasting; | 2016 |
Naringenin pre-treatment inhibits neuroapoptosis and ameliorates cognitive impairment in rats exposed to isoflurane anesthesia by regulating the PI3/Akt/PTEN signalling pathway and suppressing NF-κB-mediated inflammation.
Topics: Administration, Inhalation; Anesthesia; Animals; Apoptosis; Behavior, Animal; Caspase 3; Cognitive D | 2016 |
Isoflurane prevents acquired epilepsy in rat models of temporal lobe epilepsy.
Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Electrocorticography; Epilepsy, Temporal Lobe; | 2016 |
Neuroprotective effects of vitexin against isoflurane-induced neurotoxicity by targeting the TRPV1 and NR2B signaling pathways.
Topics: Animals; Apigenin; Apoptosis; Calcium; Caspase 3; Cell Survival; Cytosol; Humans; Inflammation; Isof | 2016 |
Calcineurin/nuclear factor-κB signaling mediates isoflurane-induced hippocampal neuroinflammation and subsequent cognitive impairment in aged rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Calcineurin; Cognitive Dysfunction; Hippocampus; Humans; In | 2017 |
Sevoflurane, Compared With Isoflurane, Minimizes Lung Damage in Pulmonary but Not in Extrapulmonary Acute Respiratory Distress Syndrome in Rats.
Topics: A549 Cells; Anesthetics; Animals; Escherichia coli; Female; Humans; Inflammation; Interleukin-6; Iso | 2017 |
Inflammatory response to nitrous oxide in the central nervous system.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Cerebral Cortex; Gerbillinae; Halothane; Inflammati | 2008 |
Heme oxygenase-1 mediates the anti-inflammatory effect of isoflurane preconditioning in LPS-stimulated macrophages.
Topics: Anesthetics, Inhalation; Animals; Cell Line; Heme Oxygenase-1; Inflammation; Isoflurane; Lipopolysac | 2009 |
Subanesthetic dose of isoflurane protects against zymosan-induced generalized inflammation and its associated acute lung injury in mice.
Topics: Acute Lung Injury; Amitrole; Animals; Catalase; Inflammation; Isoflurane; Male; Mice; Multiple Organ | 2010 |
Evaluation of the anti-inflammatory effects of ellagic acid.
Topics: Anesthetics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; | 2010 |
Impact of anesthesia, analgesia, and euthanasia technique on the inflammatory cytokine profile in a rodent model of severe burn injury.
Topics: Acute-Phase Reaction; Analgesia; Analgesics; Anesthesia, General; Anesthetics; Animals; Buprenorphin | 2010 |
Deleterious impact of a γ-aminobutyric acid type A receptor preferring general anesthetic when used in the presence of persistent inflammation.
Topics: Adrenergic alpha-Agonists; Anesthesia, General; Anesthetics, General; Animals; Behavior, Animal; Exc | 2011 |
Isoflurane causes neocortical but not hippocampal-dependent memory impairment in mice.
Topics: Amnesia; Anesthetics, Inhalation; Animals; Behavior, Animal; Buprenorphine; Conditioning, Operant; E | 2012 |
Inflammatory immune responses in a reproducible mouse brain death model.
Topics: Anesthesia; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Blood Pressure; Brain De | 2012 |
Differential general anesthetic effects on microglial cytokine expression.
Topics: Alzheimer Disease; Anesthetics; Cells, Cultured; Cytokines; Gene Expression Regulation; Humans; Infl | 2013 |
Isoflurane pretreatment inhibits lipopolysaccharide-induced inflammation in rats.
Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Endothelium, Vascular; Inflamm | 2003 |
Isoflurane pretreatment supports hemodynamics and leukocyte rolling velocities in rat mesentery during lipopolysaccharide-induced inflammation.
Topics: Anesthetics, Inhalation; Animals; Blood Flow Velocity; Blood Pressure; Body Temperature; Concanavali | 2004 |
Isoflurane inhibits cardiac myocyte apoptosis during oxidative and inflammatory stress by activating Akt and enhancing Bcl-2 expression.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Biotransformation; Caspases; Cell Lin | 2005 |
General anesthesia delays the inflammatory response and increases survival for mice with endotoxic shock.
Topics: Anesthesia, General; Anesthetics, General; Animals; Cytokines; Disease Models, Animal; Inflammation; | 2006 |
Isoflurane protects against renal ischemia and reperfusion injury and modulates leukocyte infiltration in mice.
Topics: Animals; Granulocyte Colony-Stimulating Factor; Inflammation; Interleukin-3; Isoflurane; Kidney; Kid | 2007 |
The beta-adrenoceptor antagonist propranolol counteracts anti-inflammatory effects of isoflurane in rat endotoxemia.
Topics: Adrenergic beta-Antagonists; Anesthetics, Inhalation; Animals; Anti-Inflammatory Agents; Blood Press | 2007 |
Inflammation affects sufentanil consumption in ulcerative colitis.
Topics: Acute Disease; Adolescent; Adult; Anastomosis, Surgical; Anesthetics, Inhalation; Anesthetics, Intra | 2008 |
Sevoflurane-mediated activation of p38-mitogen-activated stresskinase is independent of apoptosis in Jurkat T-cells.
Topics: Anesthetics, Inhalation; Apoptosis; Caspases; Desflurane; Enzyme Activation; Humans; Inflammation; I | 2008 |
Anesthetics impact the resolution of inflammation.
Topics: Anesthetics; Animals; Apoptosis; Flow Cytometry; Humans; Inflammation; Isoflurane; Leukocytes; Lidoc | 2008 |