isoflurane has been researched along with Injury, Ischemia-Reperfusion in 115 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
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" In the previous study, the neuroprotection of isoflurane postconditioning (ISPOC) against cerebral ischemia-reperfusion (I/R) injury has been addressed, with particular relevance to the role of BMP7." | 8.02 | Isoflurane post-conditioning attenuates cerebral ischemia/reperfusion injury by reducing apoptotic through activating the BMP7/SMAD signaling pathway in rats. ( Dai, Z; Fan, S; Ge, M; Li, Y; Qin, X; Shao, X; Wang, R; Wang, S; Yin, J; Zhai, J, 2021) |
"Isoflurane has been studied in ischemia-reperfusion injury, while the regulatory mechanism by which isoflurane regulates microRNA(miR)-9-3p in hepatic ischemia/reperfusion injury (HIRI) via targeting fibronectin type III domain containing 3B (FNDC3B) remains seldom investigated." | 8.02 | Isoflurane upregulates microRNA-9-3p to protect rats from hepatic ischemia-reperfusion injury through inhibiting fibronectin type III domain containing 3B. ( Guo, L; Song, S; Wang, H; Wang, Y, 2021) |
"Isoflurane postconditioning alleviates cerebral ischemic-reperfusion injury (CIRI), but the underlying mechanism has not been fully clarified." | 7.96 | TGF-β3/Smad3 Contributes to Isoflurane Postconditioning Against Cerebral Ischemia-Reperfusion Injury by Upregulating MEF2C. ( Chen, L; Li, Y; Ma, K; Si, J; Wang, S; Yang, C; Yang, Y; Yin, J, 2020) |
" This study aimed to investigate the relationship between AQP4, bone morphogenetic protein 4 (BMP4)/Smad1/5/8 signaling pathway and isoflurane post-conditiong, which has effects on brain edema in rats with cerebral ischemia/reperfusion (I/R) injury." | 7.88 | Isoflurane post-conditioning down-regulates expression of aquaporin 4 in rats with cerebral ischemia/reperfusion injury and is possibly related to bone morphogenetic protein 4/Smad1/5/8 signaling pathway. ( Dai, Z; Ge, M; Li, Y; Liu, X; Ma, K; Peng, L; Si, J; Wang, S; Xie, L; Yin, J; Yuan, M; Zhang, G, 2018) |
"Early apoptosis was significantly higher in isoflurane and propofol anesthetized animals subjected to renal ischemia-reperfusion injury when compared to both cyclosporine A treated and sham groups." | 7.85 | Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats. ( Carvalho, LR; Castiglia, YM; Deffune, E; Golim, MA; Lemos, SV; Módolo, NS; Nascimento, PD; Souza, AV; Vianna, IG; Vianna, PT, 2017) |
"Our results demonstrate that the administration of inhaled isoflurane in spinal cord ischemia-reperfusion injury impairs the recovery of motor function." | 7.85 | Isoflurane Impairs Motor Function Recovery by Increasing Neuroapoptosis and Degeneration During Spinal Ischemia-Reperfusion Injury in Rats. ( Fang, SY; Lam, CF; Lee, JS; Roan, JN; Tsai, YC, 2017) |
"Isoflurane has a pharmacological preconditioning effect against ischemia injury in the heart, kidney, and brain, but whether and how isoflurane preconditioning protects livers against ischemia and reperfusion (IR) injury is unclear." | 7.85 | Isoflurane Preconditioning Alleviated Murine Liver Ischemia and Reperfusion Injury by Restoring AMPK/mTOR-Mediated Autophagy. ( Ding, Z; Gao, M; Li, J; Liu, S; Lu, T; Pan, X; Rao, Z; Sun, J; Yu, D; Zhang, H, 2017) |
"Hepatic ischemia induced significant degree of I/R injuries in both isoflurane and sevoflurane non-IP groups." | 7.85 | Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats. ( Gwak, MS; Han, S; Jeong, JS; Kim, D; Kim, GS; Kim, KY; Ko, JS; Ryu, S; Shin, BS, 2017) |
"Isoflurane does not protect from brain death-associated aggravation of cold hepatic ischemia-reperfusion injury." | 7.81 | Isoflurane does not protect from brain death-associated aggravation of cold hepatic ischemia-reperfusion injury. ( Keppler, U; Menger, MD; Moussavian, MR; Schilling, MK; Strowitzki, MJ; von Heesen, M, 2015) |
"The volatile anesthetic isoflurane protects against renal ischemia and reperfusion injury by releasing renal tubular TGF-β1." | 7.79 | The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury. ( Brown, KM; D'Agati, VD; Ham, A; Kim, JY; Kim, M; Lee, HT, 2013) |
"To study the effect of isoflurane (Iso) or propofol (Prop) anesthesia on renal ischemia/reperfusion injury (IRI) during transient hyperglycemia." | 7.79 | Do propofol and isoflurane protect the kidney against ischemia/reperfusion injury during transient hyperglycemia? ( Carraretto, AR; Carvalho, LR; Castiglia, YM; Deffune, E; Golim, Mde A; Souza, AV; Vianna Filho, PT; Vianna, PT, 2013) |
"To evaluate the effect of N-acetylcysteine, as a renoprotective agent, when administered early after anesthesia induction, against ischemia/reperfusion injury in rats anesthetized with isoflurane." | 7.78 | Prevention of renal ischemia/reperfusion injury in rats using acetylcysteine after anesthesia with isoflurane. ( Braz, LG; Castiglia, YM; Fabris, VE; Mansano, AM; Silva, LM; Vianna, PT, 2012) |
"Our data suggested that isoflurane preconditioning provided a protection against renal ischemic-reperfusion injury which is very likely due to hypoxia inducible factor-1 α upregulation." | 7.77 | Pre-treatment with isoflurane ameliorates renal ischemic-reperfusion injury in mice. ( Cheng, J; Huang, H; Liu, J; Ma, D; Vizcaychipi, MP; Zhang, L; Zhao, H, 2011) |
"St Thomas cardioplegia solution supplemented with emulsified isoflurane enhanced its cardioprotection in an isolated heart ischemia reperfusion injury model in rats." | 7.76 | Cardioprotection afforded by St Thomas solution is enhanced by emulsified isoflurane in an isolated heart ischemia reperfusion injury model in rats. ( Huang, H; Li, T; Liu, J; Liu, S; Yanfang, C; Zhang, W, 2010) |
"The purpose of this investigation was to examine the effect of isoflurane, remifentanil, and preconditioning in renal ischemia/reperfusion injury (IRI)." | 7.75 | Remifentanil, isoflurane, and preconditioning attenuate renal ischemia/reperfusion injury in rats. ( Beier, S; Braz, JR; Castiglia, YM; de Assis Golim, M; Deffune, E; Reinoldes Bizarria Guilherme, G; Vianna Filho, PT; Vianna, PT; Viero, RM; Vitória, A, 2009) |
"Preconditioning with emulsified isoflurane protects the liver from ischemia/reperfusion injury and this effect me be mediated by Kupffer cells." | 7.74 | [Protection of liver against ischemia/reperfusion injury by Kupffer cell mediated emulsified isoflurane preconditioning: experiment with rats]. ( Li, Q; Lü, H; Ren, HM; Xu, LY; Yang, LQ; Yu, WF; Zhu, M, 2007) |
"This study provides first evidence that pretreatment with the nontoxic and clinically approved anesthetic isoflurane induces hepatic HO-1 expression, and thereby protects rat livers from ischemia/reperfusion injury." | 7.74 | Heme oxygenase-1 induction by the clinically used anesthetic isoflurane protects rat livers from ischemia/reperfusion injury. ( Geiger, KK; Halverscheid, L; Hoetzel, A; Humar, M; Loop, T; Pannen, BH; Schmidt, R; Tritschler, E, 2007) |
"Desflurane shows better preservation of mitochondrial function at 4 h after cerebral ischemia reperfusion injury, indicated by inhibition of mitochondrial swelling, increase of membrane potential, and improvement of functions of mitochondria respiratory complexes I + III and IV when compared with halothane." | 7.74 | Desflurane affords greater protection than halothane in the function of mitochondria against forebrain ischemia reperfusion injury in rats. ( Cui, X; Ding, W; Li, W; Wei, X; Zhang, B; Zhou, H, 2008) |
" In the current study, we investigated whether isoflurane inhalation during warm ischemia could attenuate ischemia reperfusion injury (IRI) of the lung." | 7.73 | Isoflurane inhalation after circulatory arrest protects against warm ischemia reperfusion injury of the lungs. ( Bando, T; Chen, F; Fujinaga, T; Fukuse, T; Hamakawa, H; Hanaoka, N; Nakamura, T; Omasa, M; Sakai, H; Ueda, S; Wada, H; Zhang, J, 2006) |
"To obtain more information on the cerebral ischemia and reperfusion injury under desflurane anesthesia, we compared the infarct volume and lactate dehydrogenase (LDH) activity in rats subjected to focal cerebral ischemia during different concentration of desflurane anesthesia." | 7.72 | The effect of desflurane on ameliorating cerebral infarction in rats subjected to focal cerebral ischemia-reperfusion injury. ( Chih, CL; Huang, SS; Hung, WC; Lin, SM; Mok, MS; Tsai, SK, 2004) |
"This study was designed to test the hypothesis that propofol, which possesses antioxidant properties, would produce greater protection than isoflurane in cerebral ischaemia reperfusion injury, at dose levels that produced similar affects on brain electrical activity." | 7.69 | Propofol neuroprotection in a rat model of ischaemia reperfusion injury. ( Jones, JG; Matta, BF; Menon, DK; Tisavipat, N; Young, Y, 1997) |
"Isoflurane post-treatment may enhance autophagy by activating the AMPK/ULK1 signaling pathway and further inhibit the release of inflammatory factors from NLRP3 inflammasomes, thereby ameliorating neurological function and cognitive impairment and exerting a protective effect on the brain in CIRI rats." | 5.91 | Isoflurane Enhances Autophagy by Activating AMPK/ULK1, Inhibits NLRP3, and Reduces Cognitive Impairment After Cerebral Ischemia-Reperfusion Injury in Rats. ( Li, N; Li, Y; Ma, K; Qin, X; Wang, R; Wang, S; Yin, J; Zhai, J; Zhang, X, 2023) |
"Ischaemic stroke is a severe disease worldwide." | 5.72 | Isoflurane Attenuates Cerebral Ischaemia-Reperfusion Injury via the TLR4-NLRP3 Signalling Pathway in Diabetic Mice. ( Guo, WJ; Hong, P; Huang, XX; Li, FX; Lin, HB; Tang, ZY; Wang, JW; Xu, SY; Zhang, HF; Zhang, YJ, 2022) |
"Pretreatment with isoflurane suppressed renal NF-κB activation, leading to a reduction in proinflammatory molecules (high-mobility group box 1, interleukin-1β, and tumor necrosis factor-α) both in the kidneys and circulation." | 5.40 | Isoflurane preconditioning ameliorates renal ischemia-reperfusion injury through antiinflammatory and antiapoptotic actions in rats. ( Guo, X; Li, M; Li, Z; Liang, Y; Mo, N; Wang, J; Wang, Y; Zhuang, Z, 2014) |
"Isoflurane has an acute preconditioning effectiveness against ischemia in kidney, but this beneficial effectiveness can only last for 2-3 hours." | 5.36 | [Isoflurane produces delayed preconditioning against renal ischemia/reperfusion injury via hypoxia inducible factor 1 alpha activation]. ( Cheng, J; Huang, H; Liu, J; Ma, D; Zhang, L, 2010) |
"Ischemia was evident by reduced portal vein flow and oxygen consumption, and caused an increase in lactate production." | 5.29 | Effects of halothane, isoflurane and sevoflurane on ischemia-reperfusion injury in the perfused liver of fasted rats. ( Imai, M; Inaba, H; Kon, S, 1996) |
" In the previous study, the neuroprotection of isoflurane postconditioning (ISPOC) against cerebral ischemia-reperfusion (I/R) injury has been addressed, with particular relevance to the role of BMP7." | 4.02 | Isoflurane post-conditioning attenuates cerebral ischemia/reperfusion injury by reducing apoptotic through activating the BMP7/SMAD signaling pathway in rats. ( Dai, Z; Fan, S; Ge, M; Li, Y; Qin, X; Shao, X; Wang, R; Wang, S; Yin, J; Zhai, J, 2021) |
"The mechanisms of brain protection during ischaemic reperfusion injury induced by isoflurane (ISO) post-conditioning are unclear." | 4.02 | Isoflurane post-conditioning contributes to anti-apoptotic effect after cerebral ischaemia in rats through the ERK5/MEF2D signaling pathway. ( Ge, M; Li, N; Li, Y; Qin, X; Wang, S; Xu, F; Yin, J; Zhai, J; Zhang, Q; Zhou, W, 2021) |
"Isoflurane has been studied in ischemia-reperfusion injury, while the regulatory mechanism by which isoflurane regulates microRNA(miR)-9-3p in hepatic ischemia/reperfusion injury (HIRI) via targeting fibronectin type III domain containing 3B (FNDC3B) remains seldom investigated." | 4.02 | Isoflurane upregulates microRNA-9-3p to protect rats from hepatic ischemia-reperfusion injury through inhibiting fibronectin type III domain containing 3B. ( Guo, L; Song, S; Wang, H; Wang, Y, 2021) |
"Isoflurane postconditioning alleviates cerebral ischemic-reperfusion injury (CIRI), but the underlying mechanism has not been fully clarified." | 3.96 | TGF-β3/Smad3 Contributes to Isoflurane Postconditioning Against Cerebral Ischemia-Reperfusion Injury by Upregulating MEF2C. ( Chen, L; Li, Y; Ma, K; Si, J; Wang, S; Yang, C; Yang, Y; Yin, J, 2020) |
" This study aimed to investigate the relationship between AQP4, bone morphogenetic protein 4 (BMP4)/Smad1/5/8 signaling pathway and isoflurane post-conditiong, which has effects on brain edema in rats with cerebral ischemia/reperfusion (I/R) injury." | 3.88 | Isoflurane post-conditioning down-regulates expression of aquaporin 4 in rats with cerebral ischemia/reperfusion injury and is possibly related to bone morphogenetic protein 4/Smad1/5/8 signaling pathway. ( Dai, Z; Ge, M; Li, Y; Liu, X; Ma, K; Peng, L; Si, J; Wang, S; Xie, L; Yin, J; Yuan, M; Zhang, G, 2018) |
"Isoflurane has a pharmacological preconditioning effect against ischemia injury in the heart, kidney, and brain, but whether and how isoflurane preconditioning protects livers against ischemia and reperfusion (IR) injury is unclear." | 3.85 | Isoflurane Preconditioning Alleviated Murine Liver Ischemia and Reperfusion Injury by Restoring AMPK/mTOR-Mediated Autophagy. ( Ding, Z; Gao, M; Li, J; Liu, S; Lu, T; Pan, X; Rao, Z; Sun, J; Yu, D; Zhang, H, 2017) |
"Early apoptosis was significantly higher in isoflurane and propofol anesthetized animals subjected to renal ischemia-reperfusion injury when compared to both cyclosporine A treated and sham groups." | 3.85 | Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats. ( Carvalho, LR; Castiglia, YM; Deffune, E; Golim, MA; Lemos, SV; Módolo, NS; Nascimento, PD; Souza, AV; Vianna, IG; Vianna, PT, 2017) |
"Hepatic ischemia induced significant degree of I/R injuries in both isoflurane and sevoflurane non-IP groups." | 3.85 | Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats. ( Gwak, MS; Han, S; Jeong, JS; Kim, D; Kim, GS; Kim, KY; Ko, JS; Ryu, S; Shin, BS, 2017) |
"Our results demonstrate that the administration of inhaled isoflurane in spinal cord ischemia-reperfusion injury impairs the recovery of motor function." | 3.85 | Isoflurane Impairs Motor Function Recovery by Increasing Neuroapoptosis and Degeneration During Spinal Ischemia-Reperfusion Injury in Rats. ( Fang, SY; Lam, CF; Lee, JS; Roan, JN; Tsai, YC, 2017) |
"Isoflurane does not protect from brain death-associated aggravation of cold hepatic ischemia-reperfusion injury." | 3.81 | Isoflurane does not protect from brain death-associated aggravation of cold hepatic ischemia-reperfusion injury. ( Keppler, U; Menger, MD; Moussavian, MR; Schilling, MK; Strowitzki, MJ; von Heesen, M, 2015) |
"To study the effect of isoflurane (Iso) or propofol (Prop) anesthesia on renal ischemia/reperfusion injury (IRI) during transient hyperglycemia." | 3.79 | Do propofol and isoflurane protect the kidney against ischemia/reperfusion injury during transient hyperglycemia? ( Carraretto, AR; Carvalho, LR; Castiglia, YM; Deffune, E; Golim, Mde A; Souza, AV; Vianna Filho, PT; Vianna, PT, 2013) |
" show that isoflurane uses a tubule-based transforming growth factor-β/CD73-dependent process that generates adenosine to protect mice from ischemic acute kidney injury (AKI) with effects to prevent the 'no-reflow phenomenon' and decrease inflammation." | 3.79 | The conundrum of protection from AKI by adenosine in rodent clamp ischemia models. ( Venkatachalam, MA; Weinberg, JM, 2013) |
"The volatile anesthetic isoflurane protects against renal ischemia and reperfusion injury by releasing renal tubular TGF-β1." | 3.79 | The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury. ( Brown, KM; D'Agati, VD; Ham, A; Kim, JY; Kim, M; Lee, HT, 2013) |
"Our previous clinical study reported that isoflurane preconditioning and high-dose propofol posttreatment attenuated myocardial ischemia/reperfusion injury of patients in surgery with cardiopulmonary bypass (CPB)." | 3.78 | Alternative use of isoflurane and propofol confers superior cardioprotection than using one of them alone in a dog model of cardiopulmonary bypass. ( Irwin, MG; Li, H; Li, Q; Li, T; Liu, J; Wu, W; Xia, Z; Xiang, X; You, Z; Zhou, R; Zhu, D, 2012) |
"To evaluate the effect of N-acetylcysteine, as a renoprotective agent, when administered early after anesthesia induction, against ischemia/reperfusion injury in rats anesthetized with isoflurane." | 3.78 | Prevention of renal ischemia/reperfusion injury in rats using acetylcysteine after anesthesia with isoflurane. ( Braz, LG; Castiglia, YM; Fabris, VE; Mansano, AM; Silva, LM; Vianna, PT, 2012) |
"The purpose of this investigation was to examine the effect of caffeic acid phenethyl ester (CAPE) in renal ischemia/reperfusion injury in rats anesthetized with isoflurane (iso)." | 3.78 | Caffeic acid phenethyl ester effects in the kidney during ischemia and reperfusion in rats anesthetized with isoflurane. ( Carvalho, LR; Castiglia, YM; Correa, RR; de Oliveira, CC; de Souza, AV; Roso, NC; Scatena, LM; Vianna, PT, 2012) |
"Clinic relevant doses of isoflurane attenuate ischemia reperfusion injury in rats by increasing the HO-1 expression and activity." | 3.77 | Isoflurane preconditioning at clinically relevant doses induce protective effects of heme oxygenase-1 on hepatic ischemia reperfusion in rats. ( Chen, G; Liu, Y; Lv, H; Lv, X; Tao, K; Wu, F; Yang, L; Yang, T; Yu, W, 2011) |
"Our data suggested that isoflurane preconditioning provided a protection against renal ischemic-reperfusion injury which is very likely due to hypoxia inducible factor-1 α upregulation." | 3.77 | Pre-treatment with isoflurane ameliorates renal ischemic-reperfusion injury in mice. ( Cheng, J; Huang, H; Liu, J; Ma, D; Vizcaychipi, MP; Zhang, L; Zhao, H, 2011) |
" We used isoflurane as a pharmacological stimulus to enhance EC protection of CM against hypoxia and reoxygenation injury." | 3.77 | Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection. ( Baotic, I; Bienengraeber, M; Brzezinska, AK; Kersten, JR; Leucker, TM; Muravyeva, M; Pratt, PF; Warltier, DC; Weihrauch, D, 2011) |
"St Thomas cardioplegia solution supplemented with emulsified isoflurane enhanced its cardioprotection in an isolated heart ischemia reperfusion injury model in rats." | 3.76 | Cardioprotection afforded by St Thomas solution is enhanced by emulsified isoflurane in an isolated heart ischemia reperfusion injury model in rats. ( Huang, H; Li, T; Liu, J; Liu, S; Yanfang, C; Zhang, W, 2010) |
"In this study, we sought to clarify the role of inhibiting ubiquitin-conjugated protein aggregation in the formation of a neuroprotective effect after isoflurane preconditioning using a transient global cerebral ischemia-reperfusion injury mouse model." | 3.76 | Isoflurane preconditioning induces neuroprotection by attenuating ubiquitin-conjugated protein aggregation in a mouse model of transient global cerebral ischemia. ( Dong, HL; Ma, R; Tong, L; Xiong, L; Yuan, LB; Zhang, HP; Zhao, RN, 2010) |
"These data suggest that Pim-1 kinase mediates at least in part desflurane-induced preconditioning and IPC against myocardial infarction in mice." | 3.75 | Differential role of Pim-1 kinase in anesthetic-induced and ischemic preconditioning against myocardial infarction. ( Blomeyer, CA; Kehl, F; Kellermann, A; Lange, M; Lotz, CA; Redel, A; Roewer, N; Smul, TM; Stumpner, J, 2009) |
"The purpose of this investigation was to examine the effect of isoflurane, remifentanil, and preconditioning in renal ischemia/reperfusion injury (IRI)." | 3.75 | Remifentanil, isoflurane, and preconditioning attenuate renal ischemia/reperfusion injury in rats. ( Beier, S; Braz, JR; Castiglia, YM; de Assis Golim, M; Deffune, E; Reinoldes Bizarria Guilherme, G; Vianna Filho, PT; Vianna, PT; Viero, RM; Vitória, A, 2009) |
"Desflurane shows better preservation of mitochondrial function at 4 h after cerebral ischemia reperfusion injury, indicated by inhibition of mitochondrial swelling, increase of membrane potential, and improvement of functions of mitochondria respiratory complexes I + III and IV when compared with halothane." | 3.74 | Desflurane affords greater protection than halothane in the function of mitochondria against forebrain ischemia reperfusion injury in rats. ( Cui, X; Ding, W; Li, W; Wei, X; Zhang, B; Zhou, H, 2008) |
"Preconditioning with emulsified isoflurane protects the liver from ischemia/reperfusion injury and this effect me be mediated by Kupffer cells." | 3.74 | [Protection of liver against ischemia/reperfusion injury by Kupffer cell mediated emulsified isoflurane preconditioning: experiment with rats]. ( Li, Q; Lü, H; Ren, HM; Xu, LY; Yang, LQ; Yu, WF; Zhu, M, 2007) |
"This study provides first evidence that pretreatment with the nontoxic and clinically approved anesthetic isoflurane induces hepatic HO-1 expression, and thereby protects rat livers from ischemia/reperfusion injury." | 3.74 | Heme oxygenase-1 induction by the clinically used anesthetic isoflurane protects rat livers from ischemia/reperfusion injury. ( Geiger, KK; Halverscheid, L; Hoetzel, A; Humar, M; Loop, T; Pannen, BH; Schmidt, R; Tritschler, E, 2007) |
"Repeated exposure to isoflurane suppressed myocardial myoglobin release caused by both ischemia and reperfusion injury." | 3.74 | Isoflurane attenuates myoglobin release during ischemic and/or reperfusion periods. ( Akiyama, T; Kitagawa, H; Mori, H; Nosaka, S; Yamazaki, T, 2008) |
" In the current study, we investigated whether isoflurane inhalation during warm ischemia could attenuate ischemia reperfusion injury (IRI) of the lung." | 3.73 | Isoflurane inhalation after circulatory arrest protects against warm ischemia reperfusion injury of the lungs. ( Bando, T; Chen, F; Fujinaga, T; Fukuse, T; Hamakawa, H; Hanaoka, N; Nakamura, T; Omasa, M; Sakai, H; Ueda, S; Wada, H; Zhang, J, 2006) |
"To obtain more information on the cerebral ischemia and reperfusion injury under desflurane anesthesia, we compared the infarct volume and lactate dehydrogenase (LDH) activity in rats subjected to focal cerebral ischemia during different concentration of desflurane anesthesia." | 3.72 | The effect of desflurane on ameliorating cerebral infarction in rats subjected to focal cerebral ischemia-reperfusion injury. ( Chih, CL; Huang, SS; Hung, WC; Lin, SM; Mok, MS; Tsai, SK, 2004) |
"This study was designed to test the hypothesis that propofol, which possesses antioxidant properties, would produce greater protection than isoflurane in cerebral ischaemia reperfusion injury, at dose levels that produced similar affects on brain electrical activity." | 3.69 | Propofol neuroprotection in a rat model of ischaemia reperfusion injury. ( Jones, JG; Matta, BF; Menon, DK; Tisavipat, N; Young, Y, 1997) |
"Ischemia reperfusion injury (IRI) is inevitable in kidney transplantation and negatively impacts graft and patient outcome." | 2.72 | Molecular Aspects of Volatile Anesthetic-Induced Organ Protection and Its Potential in Kidney Transplantation. ( Bosch, DJ; Leuvenink, HGD; Nieuwenhuijs-Moeke, GJ, 2021) |
"Isoflurane post-treatment may enhance autophagy by activating the AMPK/ULK1 signaling pathway and further inhibit the release of inflammatory factors from NLRP3 inflammasomes, thereby ameliorating neurological function and cognitive impairment and exerting a protective effect on the brain in CIRI rats." | 1.91 | Isoflurane Enhances Autophagy by Activating AMPK/ULK1, Inhibits NLRP3, and Reduces Cognitive Impairment After Cerebral Ischemia-Reperfusion Injury in Rats. ( Li, N; Li, Y; Ma, K; Qin, X; Wang, R; Wang, S; Yin, J; Zhai, J; Zhang, X, 2023) |
"Ischaemic stroke is a severe disease worldwide." | 1.72 | Isoflurane Attenuates Cerebral Ischaemia-Reperfusion Injury via the TLR4-NLRP3 Signalling Pathway in Diabetic Mice. ( Guo, WJ; Hong, P; Huang, XX; Li, FX; Lin, HB; Tang, ZY; Wang, JW; Xu, SY; Zhang, HF; Zhang, YJ, 2022) |
"Isoflurane (ISO) is an anesthesia and can result in neuron injury." | 1.62 | Silencing of miR-302b-3p alleviates isoflurane-induced neuronal injury by regulating PTEN expression and AKT pathway. ( Fan, X; Li, L; Lu, S, 2021) |
"Desflurane had lower uptake than propofol (65 ± 21 × 10 vs 165 ± 51 × 10 g·mL·min/μmol; P = ." | 1.48 | Propofol Attenuates the Myocardial Protection Properties of Desflurane by Modulating Mitochondrial Permeability Transition. ( Andrews, DT; Heiberg, J; Royse, AG; Royse, CF, 2018) |
"Because cerebral infarct develops within 24 h after the onset of ischemia, and several therapeutic agents have been shown to reduce the infarct volume when administered at 6 h post-ischemia, we hypothesized that attenuating BBB disruption at its peak (6 h post-ischemia) can also decrease the infarct volume measured at 24 h." | 1.46 | Anesthesia-Induced Hypothermia Attenuates Early-Phase Blood-Brain Barrier Disruption but Not Infarct Volume following Cerebral Ischemia. ( Chen, KB; Lai, TW; Lee, YD; Liao, KH; Liu, YC; Pan, YL; Poon, KS; Wang, HL, 2017) |
"Post-cardiac arrest myocardial dysfunction and brain injury are the main clinical features of this complex pathophysiological process." | 1.42 | Cardiocerebral protection by emulsified isoflurane during cardiopulmonary resuscitation. ( Li, Y; Wu, MJ; Yu, H; Zhang, YJ, 2015) |
"Pretreatment with isoflurane suppressed renal NF-κB activation, leading to a reduction in proinflammatory molecules (high-mobility group box 1, interleukin-1β, and tumor necrosis factor-α) both in the kidneys and circulation." | 1.40 | Isoflurane preconditioning ameliorates renal ischemia-reperfusion injury through antiinflammatory and antiapoptotic actions in rats. ( Guo, X; Li, M; Li, Z; Liang, Y; Mo, N; Wang, J; Wang, Y; Zhuang, Z, 2014) |
"Isoflurane has an acute preconditioning effectiveness against ischemia in kidney, but this beneficial effectiveness can only last for 2-3 hours." | 1.36 | [Isoflurane produces delayed preconditioning against renal ischemia/reperfusion injury via hypoxia inducible factor 1 alpha activation]. ( Cheng, J; Huang, H; Liu, J; Ma, D; Zhang, L, 2010) |
"Posttreatment with isoflurane, but not desflurane, reduced this cell injury." | 1.35 | Isoflurane induces a postconditioning effect on bovine pulmonary arterial endothelial cells exposed to oxygen-glucose deprivation. ( Kim, JA; Li, L; Zuo, Z, 2009) |
"Filamentous middle cerebral artery occlusion (fMCAO) is the most frequently used focal cerebral ischemia model in rodents." | 1.35 | Filamentous middle cerebral artery occlusion causes ischemic damage to the retina in mice. ( Guo, Q; Namura, S; Steele, EC, 2008) |
" Compared with ISO group alone, hepatic I/R combined with LPS resulted in severer liver injury, with the levels of ALT, AST in serum, MPO activity in the liver tissue, and hepatic and serum TNF-alpha level were all increased (all P<0." | 1.35 | [Isoflurane pretreatment reduced liver injury induced by ischemia/reperfusion combined with lipopolysaccharide in rats]. ( Huang, SD; Li, Q; Lv, X; Wu, FX; Yang, LQ; Yu, WF, 2008) |
"Isoflurane was applied after OGD." | 1.35 | Postconditioning with isoflurane reduced ischemia-induced brain injury in rats. ( Jung, HH; Lee, JJ; Li, L; Zuo, Z, 2008) |
"We examined in a rabbit model of transient spinal cord ischemia (SCI) whether isoflurane (Iso) preconditioning induces ischemic tolerance to SCI in a dose-response manner, and whether this effect is dependent on mitochondrial adenosine triphosphate-dependent potassium (K(ATP)) channel." | 1.33 | Isoflurane preconditioning protects motor neurons from spinal cord ischemia: its dose-response effects and activation of mitochondrial adenosine triphosphate-dependent potassium channel. ( Hwang, JW; Jeon, YT; Kang, H; Kim, CS; Lim, SW; Oh, YS; Park, HP, 2005) |
"Isoflurane has a pharmacological preconditioning effect against ischemia in the heart and brain, but whether this also occurs in the kidney is unclear." | 1.33 | Isoflurane protects renal function against ischemia and reperfusion through inhibition of protein kinases, JNK and ERK. ( Hashiguchi, H; Koji, T; Matsumoto, M; Miyoshi, H; Morooka, H; Sumikawa, K, 2005) |
"Neurologic deficit scores (NDS) and brain infarct volumes were evaluated at 24 h." | 1.32 | Preconditioning with isoflurane produces dose-dependent neuroprotection via activation of adenosine triphosphate-regulated potassium channels after focal cerebral ischemia in rats. ( Hou, L; Lu, Z; Wu, M; Xiong, L; Zhang, X; Zheng, Y; Zhu, Z, 2003) |
"Desflurane was associated with significantly increased alveolar-capillary membrane permeability after aortic occlusion-reperfusion when compared with the fentanyl plus droperidol anesthesia or sham-operated groups (P < 0." | 1.30 | Desflurane increases pulmonary alveolar-capillary membrane permeability after aortic occlusion-reperfusion in rabbits: evidence of oxidant-mediated lung injury. ( Baird, MS; Freeman, BA; McAdams, ML; Nielsen, VG, 1998) |
"Sevoflurane-treated hearts (1 and 2 MAC) also showed decreased adhesion of PMNs (23 +/- 2." | 1.30 | Halothane, isoflurane, and sevoflurane reduce postischemic adhesion of neutrophils in the coronary system. ( Becker, BF; Conzen, PF; Flaucher, A; Gerlach, E; Kowalski, C; Peter, K; Zahler, S, 1997) |
"Ischemia was evident by reduced portal vein flow and oxygen consumption, and caused an increase in lactate production." | 1.29 | Effects of halothane, isoflurane and sevoflurane on ischemia-reperfusion injury in the perfused liver of fasted rats. ( Imai, M; Inaba, H; Kon, S, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 12 (10.43) | 18.2507 |
2000's | 30 (26.09) | 29.6817 |
2010's | 60 (52.17) | 24.3611 |
2020's | 13 (11.30) | 2.80 |
Authors | Studies |
---|---|
Zhang, YJ | 2 |
Guo, WJ | 1 |
Tang, ZY | 1 |
Lin, HB | 1 |
Hong, P | 1 |
Wang, JW | 1 |
Huang, XX | 1 |
Li, FX | 1 |
Xu, SY | 1 |
Zhang, HF | 1 |
Zhu, X | 2 |
Yang, M | 3 |
Yang, L | 5 |
Clarysse, M | 1 |
Accarie, A | 1 |
Farré, R | 1 |
Canovai, E | 1 |
Monbaliu, D | 1 |
Gunst, J | 1 |
De Hertogh, G | 1 |
Vanuytsel, T | 1 |
Pirenne, J | 1 |
Ceulemans, LJ | 1 |
Zhai, J | 3 |
Li, N | 4 |
Zhang, X | 11 |
Li, Y | 14 |
Ma, K | 6 |
Wang, R | 3 |
Qin, X | 3 |
Yin, J | 11 |
Wang, S | 10 |
Lee, SH | 1 |
Lee, JJ | 3 |
Kim, GH | 1 |
Kim, JA | 2 |
Cho, HS | 1 |
Peng, L | 3 |
Ge, M | 7 |
Han, Z | 3 |
Wang, Y | 11 |
Zhang, M | 3 |
Xie, L | 4 |
Chen, G | 2 |
Kamat, PK | 1 |
Ahmad, AS | 1 |
Doré, S | 1 |
Liu, G | 1 |
Qiao, S | 1 |
Yu, Y | 3 |
Hou, D | 1 |
Yang, Y | 4 |
Chen, L | 4 |
Si, J | 5 |
Yang, C | 4 |
Halim, AA | 1 |
Alsayed, B | 1 |
Embarak, S | 1 |
Yaseen, T | 1 |
Dabbous, S | 1 |
Fontaine, O | 1 |
Dueluzeau, R | 1 |
Raibaud, P | 1 |
Chabanet, C | 1 |
Popoff, MR | 1 |
Badoual, J | 1 |
Gabilan, JC | 1 |
Andremont, A | 1 |
Gómez, L | 1 |
Andrés, S | 1 |
Sánchez, J | 1 |
Alonso, JM | 1 |
Rey, J | 1 |
López, F | 1 |
Jiménez, A | 1 |
Yan, Z | 1 |
Zhou, L | 1 |
Zhao, Y | 3 |
Wang, J | 8 |
Huang, L | 2 |
Hu, K | 1 |
Liu, H | 4 |
Wang, H | 5 |
Guo, Z | 1 |
Song, Y | 1 |
Huang, H | 7 |
Yang, R | 1 |
Owen, TW | 1 |
Al-Kaysi, RO | 1 |
Bardeen, CJ | 1 |
Cheng, Q | 1 |
Wu, S | 1 |
Cheng, T | 1 |
Zhou, X | 1 |
Wang, B | 4 |
Zhang, Q | 6 |
Wu, X | 2 |
Yao, Y | 3 |
Ochiai, T | 1 |
Ishiguro, H | 2 |
Nakano, R | 2 |
Kubota, Y | 2 |
Hara, M | 1 |
Sunada, K | 1 |
Hashimoto, K | 1 |
Kajioka, J | 1 |
Fujishima, A | 1 |
Jiao, J | 3 |
Gai, QY | 3 |
Wang, W | 2 |
Zang, YP | 2 |
Niu, LL | 2 |
Fu, YJ | 3 |
Wang, X | 5 |
Yao, LP | 1 |
Qin, QP | 1 |
Wang, ZY | 1 |
Liu, J | 8 |
Aleksic Sabo, V | 1 |
Knezevic, P | 1 |
Borges-Argáez, R | 1 |
Chan-Balan, R | 1 |
Cetina-Montejo, L | 1 |
Ayora-Talavera, G | 1 |
Sansores-Peraza, P | 1 |
Gómez-Carballo, J | 1 |
Cáceres-Farfán, M | 1 |
Jang, J | 1 |
Akin, D | 1 |
Bashir, R | 1 |
Yu, Z | 1 |
Zhu, J | 2 |
Jiang, H | 1 |
He, C | 2 |
Xiao, Z | 1 |
Xu, J | 2 |
Sun, Q | 1 |
Han, D | 1 |
Lei, H | 1 |
Zhao, K | 2 |
Zhu, L | 1 |
Li, X | 5 |
Fu, H | 2 |
Wilson, BK | 1 |
Step, DL | 1 |
Maxwell, CL | 1 |
Gifford, CA | 1 |
Richards, CJ | 1 |
Krehbiel, CR | 1 |
Warner, JM | 1 |
Doerr, AJ | 1 |
Erickson, GE | 1 |
Guretzky, JA | 1 |
Rasby, RJ | 1 |
Watson, AK | 1 |
Klopfenstein, TJ | 1 |
Sun, Y | 4 |
Liu, Z | 4 |
Pham, TD | 1 |
Lee, BK | 1 |
Yang, FC | 1 |
Wu, KH | 1 |
Lin, WP | 1 |
Hu, MK | 1 |
Lin, L | 3 |
Shao, J | 1 |
Sun, M | 2 |
Xu, G | 1 |
Xu, N | 1 |
Liu, S | 3 |
He, H | 1 |
Dong, X | 2 |
Yang, Q | 1 |
Duan, S | 1 |
Han, J | 2 |
Zhang, C | 3 |
Yang, X | 1 |
Li, W | 4 |
Wang, T | 2 |
Campbell, DA | 1 |
Gao, K | 1 |
Zager, RA | 1 |
Johnson, ACM | 1 |
Guillem, A | 1 |
Keyser, J | 1 |
Singh, B | 1 |
Steubl, D | 1 |
Schneider, MP | 1 |
Meiselbach, H | 1 |
Nadal, J | 1 |
Schmid, MC | 1 |
Saritas, T | 1 |
Krane, V | 1 |
Sommerer, C | 1 |
Baid-Agrawal, S | 1 |
Voelkl, J | 1 |
Kotsis, F | 1 |
Köttgen, A | 1 |
Eckardt, KU | 1 |
Scherberich, JE | 1 |
Li, H | 6 |
Yao, L | 2 |
Sun, L | 4 |
Zhu, Z | 2 |
Naren, N | 1 |
Zhang, XX | 2 |
Gentile, GL | 1 |
Rupert, AS | 1 |
Carrasco, LI | 1 |
Garcia, EM | 1 |
Kumar, NG | 1 |
Walsh, SW | 1 |
Jefferson, KK | 1 |
Guest, RL | 1 |
Samé Guerra, D | 1 |
Wissler, M | 1 |
Grimm, J | 1 |
Silhavy, TJ | 1 |
Lee, JH | 2 |
Yoo, JS | 1 |
Kim, Y | 1 |
Kim, JS | 3 |
Lee, EJ | 1 |
Roe, JH | 1 |
Delorme, M | 1 |
Bouchard, PA | 1 |
Simon, M | 1 |
Simard, S | 1 |
Lellouche, F | 1 |
D'Urzo, KA | 1 |
Mok, F | 1 |
D'Urzo, AD | 1 |
Koneru, B | 1 |
Lopez, G | 1 |
Farooqi, A | 1 |
Conkrite, KL | 1 |
Nguyen, TH | 1 |
Macha, SJ | 1 |
Modi, A | 1 |
Rokita, JL | 1 |
Urias, E | 1 |
Hindle, A | 1 |
Davidson, H | 1 |
Mccoy, K | 1 |
Nance, J | 1 |
Yazdani, V | 1 |
Irwin, MS | 1 |
Yang, S | 1 |
Wheeler, DA | 1 |
Maris, JM | 1 |
Diskin, SJ | 1 |
Reynolds, CP | 1 |
Abhilash, L | 1 |
Kalliyil, A | 1 |
Sheeba, V | 1 |
Hartley, AM | 2 |
Meunier, B | 2 |
Pinotsis, N | 1 |
Maréchal, A | 2 |
Xu, JY | 1 |
Genko, N | 1 |
Haraux, F | 1 |
Rich, PR | 1 |
Kamalanathan, M | 1 |
Doyle, SM | 1 |
Xu, C | 1 |
Achberger, AM | 1 |
Wade, TL | 1 |
Schwehr, K | 1 |
Santschi, PH | 1 |
Sylvan, JB | 1 |
Quigg, A | 1 |
Leong, W | 1 |
Xu, W | 2 |
Gao, S | 1 |
Zhai, X | 1 |
Wang, C | 2 |
Gilson, E | 1 |
Ye, J | 1 |
Lu, Y | 1 |
Yan, R | 1 |
Zhang, Y | 6 |
Hu, Z | 1 |
You, Q | 1 |
Cai, Q | 1 |
Yang, D | 1 |
Gu, S | 1 |
Dai, H | 1 |
Zhao, X | 2 |
Gui, C | 1 |
Gui, J | 1 |
Wu, PK | 1 |
Hong, SK | 1 |
Starenki, D | 1 |
Oshima, K | 1 |
Shao, H | 1 |
Gestwicki, JE | 1 |
Tsai, S | 1 |
Park, JI | 1 |
Zhao, R | 1 |
Gu, Z | 1 |
Dong, C | 2 |
Guo, G | 1 |
Li, L | 10 |
Barrett, HE | 1 |
Meester, EJ | 1 |
van Gaalen, K | 1 |
van der Heiden, K | 1 |
Krenning, BJ | 1 |
Beekman, FJ | 1 |
de Blois, E | 1 |
de Swart, J | 1 |
Verhagen, HJ | 1 |
Maina, T | 1 |
Nock, BA | 1 |
Norenberg, JP | 1 |
de Jong, M | 1 |
Gijsen, FJH | 1 |
Bernsen, MR | 1 |
Martínez-Milla, J | 1 |
Galán-Arriola, C | 1 |
Carnero, M | 1 |
Cobiella, J | 1 |
Pérez-Camargo, D | 1 |
Bautista-Hernández, V | 1 |
Rigol, M | 1 |
Solanes, N | 1 |
Villena-Gutierrez, R | 1 |
Lobo, M | 1 |
Mateo, J | 1 |
Vilchez-Tschischke, JP | 1 |
Salinas, B | 1 |
Cussó, L | 1 |
López, GJ | 1 |
Fuster, V | 1 |
Desco, M | 1 |
Sanchez-González, J | 1 |
Ibanez, B | 1 |
van den Berg, P | 1 |
Schweitzer, DH | 1 |
van Haard, PMM | 1 |
Geusens, PP | 1 |
van den Bergh, JP | 1 |
Huang, X | 2 |
Xu, H | 2 |
Yang, G | 2 |
Lin, Z | 1 |
Salem, HF | 1 |
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Kharshoum, RM | 1 |
Abd El-Ghafar, OA | 1 |
Farouk, HO | 1 |
Domiciano, D | 1 |
Nery, FC | 1 |
de Carvalho, PA | 1 |
Prudente, DO | 1 |
de Souza, LB | 1 |
Chalfun-Júnior, A | 1 |
Paiva, R | 1 |
Marchiori, PER | 1 |
Lu, M | 2 |
An, Z | 1 |
Jiang, J | 3 |
Li, J | 8 |
Du, S | 1 |
Zhou, H | 2 |
Cui, J | 1 |
Wu, W | 2 |
Liu, Y | 8 |
Song, J | 1 |
Lian, Q | 1 |
Uddin Ahmad, Z | 1 |
Gang, DD | 1 |
Konggidinata, MI | 1 |
Gallo, AA | 1 |
Zappi, ME | 1 |
Yang, TWW | 1 |
Johari, Y | 1 |
Burton, PR | 1 |
Earnest, A | 1 |
Shaw, K | 1 |
Hare, JL | 1 |
Brown, WA | 1 |
Kim, GA | 1 |
Han, S | 2 |
Choi, GH | 1 |
Choi, J | 1 |
Lim, YS | 1 |
Gallo, A | 1 |
Cancelli, C | 1 |
Ceron, E | 1 |
Covino, M | 1 |
Capoluongo, E | 1 |
Pocino, K | 1 |
Ianiro, G | 1 |
Cammarota, G | 1 |
Gasbarrini, A | 1 |
Montalto, M | 1 |
Somasundar, Y | 1 |
Lu, IC | 1 |
Mills, MR | 1 |
Qian, LY | 1 |
Olivares, X | 1 |
Ryabov, AD | 1 |
Collins, TJ | 1 |
Zhao, L | 2 |
Doddipatla, S | 1 |
Thomas, AM | 1 |
Nikolayev, AA | 1 |
Galimova, GR | 1 |
Azyazov, VN | 1 |
Mebel, AM | 1 |
Kaiser, RI | 1 |
Guo, S | 1 |
Yang, P | 1 |
Yu, X | 2 |
Wu, Y | 2 |
Zhang, H | 4 |
Yu, B | 2 |
Han, B | 1 |
George, MW | 1 |
Moor, MB | 1 |
Bonny, O | 1 |
Langenberg, E | 1 |
Paik, H | 1 |
Smith, EH | 1 |
Nair, HP | 1 |
Hanke, I | 1 |
Ganschow, S | 1 |
Catalan, G | 1 |
Domingo, N | 1 |
Schlom, DG | 1 |
Assefa, MK | 1 |
Wu, G | 2 |
Hayton, TW | 1 |
Becker, B | 1 |
Enikeev, D | 1 |
Netsch, C | 1 |
Gross, AJ | 1 |
Laukhtina, E | 1 |
Glybochko, P | 1 |
Rapoport, L | 1 |
Herrmann, TRW | 1 |
Taratkin, M | 1 |
Dai, W | 1 |
Shi, J | 2 |
Carreno, J | 1 |
Kloner, RA | 1 |
Pickersgill, NA | 1 |
Vetter, JM | 1 |
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Du, K | 1 |
Venkatesh, R | 1 |
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Saad, NES | 1 |
Bhayani, SB | 1 |
Figenshau, RS | 1 |
Eriksson, J | 1 |
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Ireland, S | 1 |
Jackson, C | 1 |
Wyatt, E | 1 |
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Stancill, JS | 1 |
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Bi, YL | 1 |
Fan, Y | 2 |
Sun, YB | 1 |
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Chung, T | 1 |
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Rothenberg, SM | 1 |
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Kretzschmar, D | 1 |
Salonurmi, T | 1 |
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Ronkainen, J | 1 |
Hyötyläinen, T | 1 |
Hautajärvi, H | 1 |
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Tolonen, A | 1 |
Orešič, M | 1 |
Känsäkoski, P | 1 |
Rysä, J | 1 |
Hakkola, J | 1 |
Hukkanen, J | 1 |
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Du, Q | 1 |
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Chen, Z | 3 |
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Yu, Q | 1 |
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Liu, W | 1 |
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Huang, Y | 3 |
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Ma, Y | 1 |
Soo Lee, M | 1 |
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Gao, R | 1 |
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Chua, H | 1 |
Wang, K | 1 |
Ou, Y | 1 |
Huang, M | 1 |
Zhu, Y | 1 |
Yu, J | 1 |
Tian, J | 1 |
Zhao, M | 1 |
Hu, J | 1 |
Yao, C | 1 |
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Hu, W | 1 |
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Prass, K | 1 |
Dirnagl, U | 1 |
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Hou, L | 1 |
Lu, Z | 1 |
Tsai, SK | 1 |
Lin, SM | 1 |
Hung, WC | 1 |
Mok, MS | 1 |
Chih, CL | 1 |
Huang, SS | 1 |
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Jeon, YT | 1 |
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Kang, H | 1 |
Lim, SW | 1 |
Kim, CS | 1 |
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Morooka, H | 1 |
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Zhao, LL | 1 |
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Schlack, W | 1 |
Emala, CW | 3 |
Fujinaga, T | 1 |
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Fukuse, T | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Long-term Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT02660411] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Completed | |||
Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on 5-year Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT05343260] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Active, not recruiting | |||
Inhalatorial Sedation in Patient With SAH Versus Conventional Intravenous Sedation (GAS-SAH)[NCT00830843] | Phase 4 | 13 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
Delirium Reduction by Volatile Anesthesia in Cardiac Surgery: Prospective, Randomized, Single-blinded Study[NCT03729011] | Phase 4 | 672 participants (Anticipated) | Interventional | 2019-01-09 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
3 reviews available for isoflurane and Injury, Ischemia-Reperfusion
Article | Year |
---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Molecular Aspects of Volatile Anesthetic-Induced Organ Protection and Its Potential in Kidney Transplantation.
Topics: Anesthetics, Inhalation; Animals; Humans; Isoflurane; Kidney; Kidney Transplantation; Reperfusion In | 2021 |
Emerging graft protective strategies in clinical liver transplantation.
Topics: Anesthetics, Inhalation; Anti-Inflammatory Agents; Desflurane; Graft Rejection; Graft Survival; Huma | 2017 |
4 trials available for isoflurane and Injury, Ischemia-Reperfusion
Article | Year |
---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Comparison of antioxidant effects of isoflurane and propofol in patients undergoing donor hepatectomy.
Topics: Adolescent; Adult; Aged; Anesthesia; Antioxidants; Biomarkers; Female; Hepatectomy; Humans; Isoflura | 2015 |
Comparison of the neuroprotective effects and recovery profiles of isoflurane, sevoflurane and desflurane as neurosurgical pre-conditioning on ischemia/reperfusion cerebral injury.
Topics: Aged; Cerebrovascular Circulation; Desflurane; Female; Hemodynamics; Humans; Isoflurane; Male; Methy | 2015 |
Propofol attenuates formation of lipid peroxides in tourniquet-induced ischaemia-reperfusion injury.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Elective Surgical Procedures; Extremities; | 1997 |
109 other studies available for isoflurane and Injury, Ischemia-Reperfusion
Article | Year |
---|---|
Isoflurane Attenuates Cerebral Ischaemia-Reperfusion Injury via the TLR4-NLRP3 Signalling Pathway in Diabetic Mice.
Topics: Animals; Brain Ischemia; Diabetes Mellitus, Experimental; Humans; Infarction, Middle Cerebral Artery | 2022 |
Isoflurane Postconditioning Alleviates Ischemic Neuronal Injury Via MiR-384-5p Regulated Autophagy.
Topics: Animals; Apoptosis; Autophagy; Brain Ischemia; Glucose; Isoflurane; Mice; MicroRNAs; Neurons; Rats; | 2023 |
Protective Effect of Oxygen and Isoflurane in Rodent Model of Intestinal Ischemia-Reperfusion Injury.
Topics: Anesthetics, Inhalation; Animals; Ischemia; Isoflurane; Male; Oxygen; Rats; Rats, Sprague-Dawley; Re | 2023 |
Isoflurane Enhances Autophagy by Activating AMPK/ULK1, Inhibits NLRP3, and Reduces Cognitive Impairment After Cerebral Ischemia-Reperfusion Injury in Rats.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Brain Ischem | 2023 |
Role of reactive oxygen species at reperfusion stage in isoflurane preconditioning-induced neuroprotection.
Topics: Anesthetics, Inhalation; Animals; Cell Survival; Infarction, Middle Cerebral Artery; Isoflurane; Mal | 2019 |
TGF-β2/Smad3 Signaling Pathway Activation Through Enhancing VEGF and CD34 Ameliorates Cerebral Ischemia/Reperfusion Injury After Isoflurane Post-conditioning in Rats.
Topics: Animals; Antigens, CD34; Apoptosis; Cerebral Cortex; Hippocampus; Infarction, Middle Cerebral Artery | 2019 |
Distinctive effect of anesthetics on the effect of limb remote ischemic postconditioning following ischemic stroke.
Topics: Analgesics; Anesthetics; Animals; Brain Infarction; Brain Ischemia; Extremities; Halothane; Infarcti | 2020 |
Isoflurane improves cerebral ischemia-reperfusion injury in rats via activating MAPK signaling pathway.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Isoflurane; MAP Kinase Signaling System; Rats; Repe | 2021 |
TGF-β3/Smad3 Contributes to Isoflurane Postconditioning Against Cerebral Ischemia-Reperfusion Injury by Upregulating MEF2C.
Topics: Animals; Brain Ischemia; Infarction, Middle Cerebral Artery; Isoflurane; Male; MEF2 Transcription Fa | 2020 |
Silencing of miR-302b-3p alleviates isoflurane-induced neuronal injury by regulating PTEN expression and AKT pathway.
Topics: Animals; Apoptosis; Humans; Isoflurane; MicroRNAs; Neurons; Proto-Oncogene Proteins c-akt; PTEN Phos | 2021 |
Isoflurane post-conditioning attenuates cerebral ischemia/reperfusion injury by reducing apoptotic through activating the BMP7/SMAD signaling pathway in rats.
Topics: Animals; Apoptosis; Bone Morphogenetic Protein 7; Brain Ischemia; Ischemic Postconditioning; Isoflur | 2021 |
Isoflurane post-conditioning contributes to anti-apoptotic effect after cerebral ischaemia in rats through the ERK5/MEF2D signaling pathway.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Brain Ischemia; Cell Movement; Cell Proliferation; Gene | 2021 |
Isoflurane upregulates microRNA-9-3p to protect rats from hepatic ischemia-reperfusion injury through inhibiting fibronectin type III domain containing 3B.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Disease Models, Animal; Fibronectins; Ge | 2021 |
The protective effect of isoflurane pretreatment on liver IRI by suppressing noncanonical pyroptosis of liver macrophages.
Topics: Anesthetics, Inhalation; Animals; Calcium; Cytokines; Inflammasomes; Ischemic Preconditioning; Isofl | 2021 |
Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Apoptosis; Cell Survival; Cyclosporine; | 2017 |
Isoflurane Preconditioning Alleviated Murine Liver Ischemia and Reperfusion Injury by Restoring AMPK/mTOR-Mediated Autophagy.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Ischemia; Ischemic Preconditioning; Isoflurane; L | 2017 |
Isoflurane post-conditioning down-regulates expression of aquaporin 4 in rats with cerebral ischemia/reperfusion injury and is possibly related to bone morphogenetic protein 4/Smad1/5/8 signaling pathway.
Topics: Animals; Aquaporin 4; Bone Morphogenetic Protein 4; Brain Ischemia; Down-Regulation; Gene Expression | 2018 |
Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats.
Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Ischemia; Ischemic Precond | 2017 |
Impact of Volatile Anesthetic Agents on Early Clinical Outcomes in Liver Transplantation.
Topics: Anesthetics, Inhalation; Desflurane; Female; Graft Survival; Humans; Isoflurane; Liver; Liver Functi | 2018 |
Propofol Attenuates the Myocardial Protection Properties of Desflurane by Modulating Mitochondrial Permeability Transition.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Cardiotonic Agents; Deoxyglucose; Desflurane; Drug Ad | 2018 |
TREK-2 Mediates the Neuroprotective Effect of Isoflurane Preconditioning Against Acute Cerebral Ischemia in the Rat.
Topics: Acute Disease; Animals; Brain Ischemia; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; | 2019 |
Wnt/β-catenin signaling pathway contributes to isoflurane postconditioning against cerebral ischemia-reperfusion injury and is possibly related to the transforming growth factorβ1/Smad3 signaling pathway.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Ischemic Postconditioning; Isoflurane; Male; Rats; | 2019 |
The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury.
Topics: 5'-Nucleotidase; Acute Kidney Injury; Adenosine; Anesthetics, Inhalation; Animals; Antibodies, Neutr | 2013 |
Do propofol and isoflurane protect the kidney against ischemia/reperfusion injury during transient hyperglycemia?
Topics: Acute Disease; Anesthesia; Anesthetics; Animals; Cell Survival; Creatinine; Flow Cytometry; Hypergly | 2013 |
The protective effect of ischemic preconditioning against hepatic ischemic-reperfusion injury under isoflurane anesthesia in rats.
Topics: Anesthetics, Inhalation; Animals; Ischemic Preconditioning; Isoflurane; Liver; Male; Rats; Rats, Spr | 2013 |
The conundrum of protection from AKI by adenosine in rodent clamp ischemia models.
Topics: 5'-Nucleotidase; Acute Kidney Injury; Anesthetics, Inhalation; Animals; GPI-Linked Proteins; Humans; | 2013 |
The neuroprotective effects of isoflurane preconditioning in a murine transient global cerebral ischemia-reperfusion model: the role of the Notch signaling pathway.
Topics: Animals; Apoptosis; Ataxia; Basic Helix-Loop-Helix Transcription Factors; CA1 Region, Hippocampal; C | 2014 |
Preconditioning renoprotective effect of isoflurane in a rat model of virtual renal transplant.
Topics: Acetylcysteine; Acute Kidney Injury; Anesthetics, Inhalation; Animals; Free Radical Scavengers; Isch | 2014 |
Intravenous pretreatment with emulsified isoflurane preconditioning protects kidneys against ischemia/reperfusion injury in rats.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Emulsions; Inflammation; Ischemic | 2014 |
[The effects of preconditioning and postconditioning with isoflurane on focal cerebral ischemi/reperfusion injury in rats].
Topics: Animals; Brain; Brain Ischemia; Disease Models, Animal; Interleukin-1beta; Ischemic Postconditioning | 2014 |
The Role of SUMO-Conjugating Enzyme Ubc9 in the Neuroprotection of Isoflurane Preconditioning Against Ischemic Neuronal Injury.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Disease Models, Animal; Humans; Ischemic Precondit | 2015 |
Isoflurane preconditioning ameliorates renal ischemia-reperfusion injury through antiinflammatory and antiapoptotic actions in rats.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Ischemic Preconditioning; Isoflurane; Kidney; Male; Ra | 2014 |
Isoflurane reduces the ischemia reperfusion injury surge: a longitudinal study with MRI.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Diffusion Magnetic Resonance Imaging; Diseas | 2014 |
Isoflurane but not sevoflurane or desflurane aggravates injury to neurons in vitro and in vivo via p75NTR-NF-ĸB activation.
Topics: Anesthetics, Inhalation; Animals; Binding Sites; Cell Death; Cell Hypoxia; Cell Line, Tumor; Desflur | 2014 |
Cardiocerebral protection by emulsified isoflurane during cardiopulmonary resuscitation.
Topics: Cardiopulmonary Resuscitation; Heart Arrest; Humans; Hypothermia, Induced; Ischemic Postconditioning | 2015 |
Isoflurane does not protect from brain death-associated aggravation of cold hepatic ischemia-reperfusion injury.
Topics: Animals; Brain Death; Humans; Isoflurane; Liver; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2015 |
Isoflurane anesthesia initiated at the onset of reperfusion attenuates oxidative and hypoxic-ischemic brain injury.
Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Cerebrovascular Circulation; Disease Models, A | 2015 |
Isoflurane preconditioning provides neuroprotection against stroke by regulating the expression of the TLR4 signalling pathway to alleviate microglial activation.
Topics: Animals; Apoptosis; Biomarkers; Brain Infarction; Cells, Cultured; Chaperonin 60; Disease Models, An | 2015 |
Inhalation anesthesia of rats: influence of the fraction of inspired oxygen on limb ischemia/reperfusion injury.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Hindlimb; Isoflurane; Male; Muscles; Oxida | 2016 |
Transforming growth-beta 1 contributes to isoflurane postconditioning against cerebral ischemia-reperfusion injury by regulating the c-Jun N-terminal kinase signaling pathway.
Topics: Animals; Anthracenes; Behavior, Animal; Brain Ischemia; CA1 Region, Hippocampal; In Situ Nick-End La | 2016 |
Isoflurane preconditioning protects rat brain from ischemia reperfusion injury via up-regulating the HIF-1α expression through Akt/mTOR/s6K activation.
Topics: Animals; Apoptosis; Blotting, Western; Brain; Cell Line; Cell Survival; Disease Models, Animal; Hypo | 2016 |
TIGAR contributes to ischemic tolerance induced by cerebral preconditioning through scavenging of reactive oxygen species and inhibition of apoptosis.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain Ischemia; Cerebral Cortex; Gene Expression | 2016 |
Effects of activin A and its downstream ERK1/2 in oxygen and glucose deprivation after isoflurane-induced postconditioning.
Topics: Animals; Cell Hypoxia; Cell Survival; Cytoprotection; Dose-Response Relationship, Drug; Glucose; Hip | 2016 |
NOD2 mediates isoflurane preconditioning-induced protection of myocardial injury.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Isoflurane; Mitogen-Activated Protein Kinases; M | 2017 |
Isoflurane Impairs Motor Function Recovery by Increasing Neuroapoptosis and Degeneration During Spinal Ischemia-Reperfusion Injury in Rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Calcium-Binding Proteins; Caspase 3; Disease Models, An | 2017 |
Anesthesia-Induced Hypothermia Attenuates Early-Phase Blood-Brain Barrier Disruption but Not Infarct Volume following Cerebral Ischemia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Arterial Occlusive Diseases; Blood-Brain B | 2017 |
Repeated remote ischemic preconditioning and isoflurane anesthesia in an experimental model of renal ischemia-reperfusion injury.
Topics: Animals; Creatinine; Disease Models, Animal; Ischemic Preconditioning; Isoflurane; Kidney; Male; Pro | 2017 |
Phosphoproteome analysis of isoflurane-protected heart mitochondria: phosphorylation of adenine nucleotide translocator-1 on Tyr194 regulates mitochondrial function.
Topics: Adenine Nucleotide Translocator 1; Animals; In Vitro Techniques; Ischemic Preconditioning, Myocardia | 2008 |
Nitric oxide triggers delayed anesthetic preconditioning-induced cardiac protection via activation of nuclear factor-kappaB and upregulation of inducible nitric oxide synthase.
Topics: Anesthetics, Inhalation; Animals; Gene Expression Regulation, Enzymologic; Heart; Ischemic Precondit | 2008 |
Isoflurane induces a postconditioning effect on bovine pulmonary arterial endothelial cells exposed to oxygen-glucose deprivation.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Cattle; Cell Hypoxia; Cell Survival; Cells, Cultured; D | 2009 |
Differential role of Pim-1 kinase in anesthetic-induced and ischemic preconditioning against myocardial infarction.
Topics: Anesthetics, Inhalation; Animals; bcl-Associated Death Protein; Blood Pressure; Blotting, Western; C | 2009 |
Remifentanil, isoflurane, and preconditioning attenuate renal ischemia/reperfusion injury in rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Apoptosis; Creatinine; Ischemic Precondi | 2009 |
Cardioprotection afforded by St Thomas solution is enhanced by emulsified isoflurane in an isolated heart ischemia reperfusion injury model in rats.
Topics: Anesthetics, Inhalation; Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Creatine K | 2010 |
[Isoflurane produces delayed preconditioning against renal ischemia/reperfusion injury via hypoxia inducible factor 1 alpha activation].
Topics: Animals; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemic Preconditioning; Isoflurane; Kidney; Ma | 2010 |
Isoflurane preconditioning induces neuroprotection by attenuating ubiquitin-conjugated protein aggregation in a mouse model of transient global cerebral ischemia.
Topics: Animals; Apoptosis; Blotting, Western; CA1 Region, Hippocampal; Cell Survival; Cerebrovascular Circu | 2010 |
Volatile anesthetics might be more beneficial than propofol for postoperative liver function in cirrhotic patients receiving hepatectomy.
Topics: Anesthetics, Inhalation; Desflurane; Heme Oxygenase (Decyclizing); Hepatectomy; Humans; Hypoxia-Indu | 2010 |
Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain: isoflurane or ischemia-reperfusion?
Topics: Animals; Animals, Newborn; Apoptosis; Blood Pressure; Brain; Isoflurane; Macaca mulatta; Reperfusion | 2010 |
Isoflurane activates intestinal sphingosine kinase to protect against renal ischemia-reperfusion-induced liver and intestine injury.
Topics: Acute Kidney Injury; Anesthetics, Inhalation; Animals; Enzyme Activation; Intestinal Diseases; Intes | 2011 |
Isoflurane preconditioning at clinically relevant doses induce protective effects of heme oxygenase-1 on hepatic ischemia reperfusion in rats.
Topics: Animals; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Hemin; Ischemic Preconditioning; Isofluran | 2011 |
Pre-treatment with isoflurane ameliorates renal ischemic-reperfusion injury in mice.
Topics: Animals; Apoptosis; Blotting, Western; Creatinine; Disease Models, Animal; Erythropoietin; Hypoxia-I | 2011 |
Emulsified isoflurane preconditioning reduces lung injury induced by hepatic ischemia/reperfusion in rats.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Intercellular Adhesion Mole | 2011 |
Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection.
Topics: Animals; Butadienes; Cell Survival; Coculture Techniques; Endothelial Cells; Endothelium, Vascular; | 2011 |
Isoflurane preconditioning protects neurons from male and female mice against oxygen and glucose deprivation and is modulated by estradiol only in neurons from female mice.
Topics: Animals; Brain Ischemia; Cell Survival; Estradiol; Estrogen Antagonists; Female; Glucose; Hypoxia, B | 2011 |
Isoflurane postconditioning induces neuroprotection via Akt activation and attenuation of increased mitochondrial membrane permeability.
Topics: Animals; Blotting, Western; Brain Ischemia; Enzyme Activation; Ischemic Postconditioning; Isoflurane | 2011 |
Isoflurane anesthesia preserves liver and lung mitochondrial oxidative capacity after gut ischemia-reperfusion.
Topics: Anesthetics, Inhalation; Animals; Gastrointestinal Tract; Isoflurane; Liver; Lung; Male; Mitochondri | 2011 |
Alternative use of isoflurane and propofol confers superior cardioprotection than using one of them alone in a dog model of cardiopulmonary bypass.
Topics: Animals; Cardiopulmonary Bypass; Cardiotonic Agents; Dogs; Drug Interactions; Heart; Hemodynamics; I | 2012 |
Isoflurane post-conditioning protects against intestinal ischemia-reperfusion injury and multiorgan dysfunction via transforming growth factor-β1 generation.
Topics: Anesthetics, Inhalation; Animals; Intestines; Ischemic Postconditioning; Isoflurane; Male; Mice; Mic | 2012 |
TREK1 activation mediates spinal cord ischemic tolerance induced by isoflurane preconditioning in rats.
Topics: Anesthetics, Inhalation; Animals; Ischemic Preconditioning; Isoflurane; Male; Neurons; Neuroprotecti | 2012 |
Prevention of renal ischemia/reperfusion injury in rats using acetylcysteine after anesthesia with isoflurane.
Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Creatinine; Isoflurane; Kidney; Kidney Tubules; Ma | 2012 |
Ischemia-reperfusion injury of the mouse kidney.
Topics: Anesthetics, General; Animals; Disease Models, Animal; Female; Hypnotics and Sedatives; Isoflurane; | 2012 |
Caffeic acid phenethyl ester effects in the kidney during ischemia and reperfusion in rats anesthetized with isoflurane.
Topics: Anesthetics, Inhalation; Animals; Biomarkers; Caffeic Acids; Creatinine; Disease Models, Animal; Iso | 2012 |
Volatile anesthetics reduce invasion of colorectal cancer cells through down-regulation of matrix metalloproteinase-9.
Topics: Anesthetics, Inhalation; Colorectal Neoplasms; Desflurane; Down-Regulation; Enzyme-Linked Immunosorb | 2012 |
Volatile anesthetics reduce invasion of colorectal cancer cells through down-regulation of matrix metalloproteinase-9.
Topics: Anesthetics, Inhalation; Colorectal Neoplasms; Desflurane; Down-Regulation; Enzyme-Linked Immunosorb | 2012 |
Volatile anesthetics reduce invasion of colorectal cancer cells through down-regulation of matrix metalloproteinase-9.
Topics: Anesthetics, Inhalation; Colorectal Neoplasms; Desflurane; Down-Regulation; Enzyme-Linked Immunosorb | 2012 |
Volatile anesthetics reduce invasion of colorectal cancer cells through down-regulation of matrix metalloproteinase-9.
Topics: Anesthetics, Inhalation; Colorectal Neoplasms; Desflurane; Down-Regulation; Enzyme-Linked Immunosorb | 2012 |
In vivo electrophysiological characterization of TASK-1 deficient mice.
Topics: Adrenergic beta-Agonists; Anesthetics; Animals; Atrial Function; Baroreflex; Electric Stimulation; E | 2012 |
Isoflurane induced prolonged protection against cerebral ischemia in mice: a redox sensitive mechanism?
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Brain Ischemia; Hypoxia; Isoflurane; Male; Mice; M | 2002 |
Preconditioning with isoflurane produces dose-dependent neuroprotection via activation of adenosine triphosphate-regulated potassium channels after focal cerebral ischemia in rats.
Topics: Anesthetics, Inhalation; Animals; ATP-Binding Cassette Transporters; Blood Gas Analysis; Body Temper | 2003 |
The effect of desflurane on ameliorating cerebral infarction in rats subjected to focal cerebral ischemia-reperfusion injury.
Topics: Animals; Cerebral Infarction; Cerebrovascular Circulation; Desflurane; Hemodynamics; Humans; Infarct | 2004 |
Isoflurane preconditioning protects motor neurons from spinal cord ischemia: its dose-response effects and activation of mitochondrial adenosine triphosphate-dependent potassium channel.
Topics: Anesthetics, Inhalation; Animals; Anterior Horn Cells; Cell Death; Cell Survival; Disease Models, An | 2005 |
Isoflurane protects renal function against ischemia and reperfusion through inhibition of protein kinases, JNK and ERK.
Topics: Anesthetics, Inhalation; Animals; Extracellular Signal-Regulated MAP Kinases; Isoflurane; JNK Mitoge | 2005 |
[Protective effect of isoflurane pretreatment against pulmonary injury in canines undergoing cardiopulmonary bypass].
Topics: Animals; Cardiopulmonary Bypass; Dogs; Female; Isoflurane; Lung; Male; Random Allocation; Reperfusio | 2005 |
Isoflurane preconditioning protects human neuroblastoma SH-SY5Y cells against in vitro simulated ischemia-reperfusion through the activation of extracellular signal-regulated kinases pathway.
Topics: Butadienes; Cell Hypoxia; Cell Line, Tumor; Cell Survival; DNA, Single-Stranded; Dose-Response Relat | 2006 |
Post-conditioning by a short administration of desflurane reduced renal reperfusion injury after differing of ischaemia times in rats.
Topics: Anesthetics, Inhalation; Animals; Creatinine; Cystatin C; Cystatins; Desflurane; Ectodysplasins; Iso | 2006 |
Renal protection with isoflurane.
Topics: Anesthetics, Inhalation; Animals; Extracellular Signal-Regulated MAP Kinases; Ischemia; Isoflurane; | 2006 |
Isoflurane inhalation after circulatory arrest protects against warm ischemia reperfusion injury of the lungs.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Blood Circulation; Caspase 9; Cell Res | 2006 |
Mechanisms of cardiac protection from ischemia/reperfusion injury: a role for caveolae and caveolin-1.
Topics: Animals; Base Sequence; Caveolin 1; DNA Primers; Isoflurane; Male; Mice; Mice, Inbred C57BL; Mice, K | 2007 |
Heme oxygenase-1 induction by the clinically used anesthetic isoflurane protects rat livers from ischemia/reperfusion injury.
Topics: Analysis of Variance; Anesthetics; Animals; Blood Flow Velocity; Blotting, Northern; Blotting, Weste | 2007 |
Isoflurane protects against renal ischemia and reperfusion injury and modulates leukocyte infiltration in mice.
Topics: Animals; Granulocyte Colony-Stimulating Factor; Inflammation; Interleukin-3; Isoflurane; Kidney; Kid | 2007 |
Isoflurane mediates protection from renal ischemia-reperfusion injury via sphingosine kinase and sphingosine-1-phosphate-dependent pathways.
Topics: Anesthetics, Inhalation; Animals; Cell Line; Creatinine; Enzyme Inhibitors; Humans; Isoflurane; Kidn | 2007 |
[Protection of liver against ischemia/reperfusion injury by Kupffer cell mediated emulsified isoflurane preconditioning: experiment with rats].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Disease Models, Animal; Emulsions; Injec | 2007 |
Hepatic energy metabolism and the differential protective effects of sevoflurane and isoflurane anesthesia in a rat hepatic ischemia-reperfusion injury model.
Topics: Adenosine Triphosphate; Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotrans | 2008 |
Desflurane affords greater protection than halothane in the function of mitochondria against forebrain ischemia reperfusion injury in rats.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Desfl | 2008 |
Anesthetics and natural heme oxygenase-1 inducers: waiting for carbon monoxide?
Topics: Anesthetics; Animals; Anthocyanins; Antioxidants; Carbon Monoxide; Curcumin; Cytoprotection; Disease | 2008 |
Isoflurane attenuates myoglobin release during ischemic and/or reperfusion periods.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Heart R | 2008 |
Desflurane preconditioning inhibits endothelial nuclear factor-kappa-B activation by targeting the proximal end of tumor necrosis factor-alpha signaling.
Topics: Active Transport, Cell Nucleus; Anesthetics, Inhalation; Cell Line; Desflurane; Endothelial Cells; E | 2008 |
Filamentous middle cerebral artery occlusion causes ischemic damage to the retina in mice.
Topics: Amaurosis Fugax; Animals; Apoptosis; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; | 2008 |
[Isoflurane pretreatment reduced liver injury induced by ischemia/reperfusion combined with lipopolysaccharide in rats].
Topics: Alanine Transaminase; Animals; Disease Models, Animal; Isoflurane; Lipopolysaccharides; Liver; Male; | 2008 |
Postconditioning with isoflurane reduced ischemia-induced brain injury in rats.
Topics: Anesthetics, Inhalation; Animals; Brain; Decanoic Acids; Dose-Response Relationship, Drug; Glyburide | 2008 |
Effects of halothane, isoflurane and sevoflurane on ischemia-reperfusion injury in the perfused liver of fasted rats.
Topics: Anesthetics, Inhalation; Animals; Ethers; Halothane; Ischemia; Isoflurane; L-Lactate Dehydrogenase; | 1996 |
Isoflurane and halothane increase adenosine triphosphate preservation, but do not provide additive recovery of function after ischemia, in preconditioned rat hearts.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Halothane; Hemodynamics; Isoflurane; Male; Myocardi | 1997 |
Isoflurane attenuates early neutrophil-independent hypoxia-reoxygenation injuries in the reperfused liver in fasted rats.
Topics: Anesthetics, Inhalation; Animals; Carbohydrate Metabolism; Cytochrome c Group; Fasting; Isoflurane; | 1997 |
Halothane, isoflurane, and sevoflurane reduce postischemic adhesion of neutrophils in the coronary system.
Topics: Anesthetics, Inhalation; Animals; Cell Adhesion; Cells, Cultured; Coronary Vessels; Endothelium, Vas | 1997 |
A method for long duration anaesthesia for a new hindlimb ischaemia-reperfusion model in mice.
Topics: Analgesics, Opioid; Anesthesia; Anesthetics, Inhalation; Animals; Body Temperature; Buprenorphine; D | 1997 |
Propofol neuroprotection in a rat model of ischaemia reperfusion injury.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Antioxidants; Brain; Brain I | 1997 |
Core and penumbral nitric oxide synthase activity during cerebral ischemia and reperfusion.
Topics: Anesthetics, Inhalation; Animals; Antioxidants; Arterial Occlusive Diseases; Biopterins; Brain Ische | 1998 |
Desflurane increases pulmonary alveolar-capillary membrane permeability after aortic occlusion-reperfusion in rabbits: evidence of oxidant-mediated lung injury.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Capillary Permeability; Desflurane; Drop | 1998 |
Effect of isoflurane on epinephrine-induced arrhythmias in ischemic-reperfused dog hearts.
Topics: Anesthetics, Inhalation; Animals; Arrhythmias, Cardiac; Blood Pressure; Calcium; Calcium Channel Blo | 1998 |
Isoflurane administration before ischemia and during reperfusion attenuates ischemia/reperfusion-induced injury of isolated rabbit lungs.
Topics: Anesthetics, Inhalation; Animals; In Vitro Techniques; Isoflurane; Lung; Male; Pulmonary Circulation | 1999 |
Core and penumbral nitric oxide synthase activity during cerebral ischemia and reperfusion in the rat pup.
Topics: Animals; Brain; Brain Ischemia; Disease Models, Animal; Isoflurane; Male; Nitric Oxide Synthase; Rat | 1999 |
Isoflurane-sevoflurane adminstration before ischemia attenuates ischemia-reperfusion-induced injury in isolated rat lungs.
Topics: Anesthetics, Inhalation; Animals; Capillary Permeability; In Vitro Techniques; Isoflurane; L-Lactate | 2000 |
Recovery from myocardial stunning is faster with desflurane compared with propofol in chronically instrumented dogs.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Pressure; Desflurane; Dogs; Female | 2000 |