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isoflurane and Hypocapnia

isoflurane has been researched along with Hypocapnia in 17 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Hypocapnia: Clinical manifestation consisting of a deficiency of carbon dioxide in arterial blood.

Research Excerpts

ExcerptRelevanceReference
"Phenylephrine was administered to increase arterial blood pressure in 6 monkeys anesthetized with isoflurane during both normocapnia (arterial partial pressure of CO2 35 to 44 mm Hg) and hypocapnia (arterial partial pressure of CO2 23 to 29 mm Hg)."7.76Hypocapnia enhances the pressor effect of phenylephrine during isoflurane anesthesia in monkeys. ( Adams, DC; Schwartz, AE, 2010)
" During isoflurane anesthesia, we investigated the effects of hypocapnia and the effects of a phenylephrine infusion, on aZFP and RAP."7.75The effects of hypocapnia and the cerebral autoregulatory response on cerebrovascular resistance and apparent zero flow pressure during isoflurane anesthesia. ( McCulloch, TJ; Turner, MJ, 2009)
"The aim of this study was to develop a nonlinear mixed-effects model for the increase in cerebral oximetry (rSO(2)) during the rapid introduction of desflurane, and to determine the effect of hypocapnia and N(2)O on the model."7.75Hypocapnia attenuates, and nitrous oxide disturbs the cerebral oximetric response to the rapid introduction of desflurane. ( Cho, H; Choi, JG; Chung, S; In, J; Kim, KO; Lee, JH; Lee, Y; Yoon, DI, 2009)
"More cerebral vasodilation at hypocapnia with high doses of desflurane than with sevoflurane or isoflurane indicates that desflurane might be less suitable for neuroanaesthesia than sevoflurane and isoflurane."7.72Desflurane results in higher cerebral blood flow than sevoflurane or isoflurane at hypocapnia in pigs. ( Akeson, J; Holmström, A; Rosén, I, 2004)
"Due to a few reports of cerebral dysfunction in connection with isoflurane-induced hypotension and concomitant hypocapnia, positron emission tomography (PET) was used to measure cerebral oxygenation and blood flow during similar conditions with isoflurane or propofol."7.69Cerebral normoxia in the rhesus monkey during isoflurane- or propofol-induced hypotension and hypocapnia, despite disparate blood-flow patterns. A positron emission tomography study. ( Andersson, J; Enlund, M; Hartvig, P; Valtysson, J; Wiklund, L, 1997)
" Twenty-nine patients undergoing craniotomy for frontotemporal gliomas were randomized to receive intravenous anesthesia with propofol or inhalational anesthesia with isoflurane."5.12Cerebrovascular reactivity to carbon dioxide in the normal and abnormal cerebral hemispheres under anesthesia in patients with frontotemporal gliomas. ( Pillai, SV; Rao, GS, 2006)
" During isoflurane anesthesia, we investigated the effects of hypocapnia and the effects of a phenylephrine infusion, on aZFP and RAP."3.75The effects of hypocapnia and the cerebral autoregulatory response on cerebrovascular resistance and apparent zero flow pressure during isoflurane anesthesia. ( McCulloch, TJ; Turner, MJ, 2009)
"The aim of this study was to develop a nonlinear mixed-effects model for the increase in cerebral oximetry (rSO(2)) during the rapid introduction of desflurane, and to determine the effect of hypocapnia and N(2)O on the model."3.75Hypocapnia attenuates, and nitrous oxide disturbs the cerebral oximetric response to the rapid introduction of desflurane. ( Cho, H; Choi, JG; Chung, S; In, J; Kim, KO; Lee, JH; Lee, Y; Yoon, DI, 2009)
"More cerebral vasodilation at hypocapnia with high doses of desflurane than with sevoflurane or isoflurane indicates that desflurane might be less suitable for neuroanaesthesia than sevoflurane and isoflurane."3.72Desflurane results in higher cerebral blood flow than sevoflurane or isoflurane at hypocapnia in pigs. ( Akeson, J; Holmström, A; Rosén, I, 2004)
"Previous studies to determine whether desflurane increases cerebrospinal fluid (CSF) pressure are inconclusive because none have included all of the following: multiple doses of desflurane, administration for at least several hours, examination at normo- and hypocapnia, a concurrent comparison group, direct measurement of both intra- and extracranial CSF pressures, and measurement of venous pressures that influence CSF pressure."3.69CSF, sagittal sinus, and jugular venous pressures during desflurane or isoflurane anesthesia in dogs. ( Artru, AA; Doepfner, P; Powers, K, 1994)
"Hypocapnia-induced vasoconstriction of isolated dog cerebral arteries precontracted with KCl is more susceptible to halothane than isoflurane or sevoflurane."3.69Volatile anaesthetics attenuate hypocapnia-induced constriction in isolated dog cerebral arteries. ( Hatano, Y; Mizumoto, K; Ogawa, K; Yamamoto, M, 1997)
"Due to a few reports of cerebral dysfunction in connection with isoflurane-induced hypotension and concomitant hypocapnia, positron emission tomography (PET) was used to measure cerebral oxygenation and blood flow during similar conditions with isoflurane or propofol."3.69Cerebral normoxia in the rhesus monkey during isoflurane- or propofol-induced hypotension and hypocapnia, despite disparate blood-flow patterns. A positron emission tomography study. ( Andersson, J; Enlund, M; Hartvig, P; Valtysson, J; Wiklund, L, 1997)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (52.94)18.2507
2000's6 (35.29)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McCulloch, TJ2
Turner, MJ1
Lee, Y2
Lee, JH1
Yoon, DI1
Kim, KO1
Chung, S1
In, J1
Choi, JG1
Cho, H1
Rioja, E1
Kerr, CL1
McDonell, WN1
Dobson, H1
Konyer, NB1
Poma, R1
Noseworthy, MD1
Schwartz, AE1
Adams, DC1
Luginbuehl, IA1
Karsli, C1
Bissonnette, B1
Holmström, A1
Rosén, I2
Akeson, J1
Boesel, TW1
Lam, AM1
Rao, GS1
Pillai, SV1
Hoffman, WE1
Charbel, FT1
Edelman, G1
Albrecht, RF1
Ausman, JI1
Artru, AA1
Powers, K1
Doepfner, P1
Ruta, TS1
Drummond, JC1
Cole, DJ1
Ogawa, K1
Yamamoto, M1
Mizumoto, K1
Hatano, Y1
Enlund, M1
Andersson, J1
Hartvig, P1
Valtysson, J1
Wiklund, L1
Otsuka, H1
Brenet, O1
Granry, JC1
Poirier, N1
Le Gall, R1
Algotsson, L1
Messeter, K1
Holmin, T1
Gravenstein, MA1
Sasse, F1
Hogan, K1

Trials

3 trials available for isoflurane and Hypocapnia

ArticleYear
Cerebrovascular reactivity to carbon dioxide is preserved during hypocapnia in children anesthetized with 1.0 MAC, but not with 1.5 MAC desflurane.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2003, Volume: 50, Issue:2

    Topics: Adolescent; Anesthesia, Inhalation; Anesthetics, Inhalation; Carbon Dioxide; Cerebrovascular Circula

2003
The effect of hypocapnia on the autoregulation of cerebral blood flow during administration of isoflurane.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:5

    Topics: Adult; Anesthetics, Inhalation; Blood Pressure; Cerebrovascular Circulation; Female; Homeostasis; Hu

2005
Cerebrovascular reactivity to carbon dioxide in the normal and abnormal cerebral hemispheres under anesthesia in patients with frontotemporal gliomas.
    Journal of neurosurgical anesthesiology, 2006, Volume: 18, Issue:3

    Topics: Adult; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Brain Neoplasms; Carbon Dioxid

2006

Other Studies

14 other studies available for isoflurane and Hypocapnia

ArticleYear
The effects of hypocapnia and the cerebral autoregulatory response on cerebrovascular resistance and apparent zero flow pressure during isoflurane anesthesia.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: Anesthetics, Inhalation; Blood Flow Velocity; Blood Pressure; Cerebrovascular Circulation; Fourier A

2009
Hypocapnia attenuates, and nitrous oxide disturbs the cerebral oximetric response to the rapid introduction of desflurane.
    Journal of Korean medical science, 2009, Volume: 24, Issue:6

    Topics: Adult; Anesthetics, Inhalation; Cerebral Cortex; Cerebrovascular Circulation; Desflurane; Female; He

2009
Effects of hypercapnia, hypocapnia, and hyperoxemia on blood oxygenation level-dependent signal intensity determined by use of susceptibility-weighted magnetic resonance imaging in isoflurane-anesthetized dogs.
    American journal of veterinary research, 2010, Volume: 71, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Brain; Dogs; Hypercapnia; Hyperoxia; Hypocapnia; Isoflurane; Magne

2010
Hypocapnia enhances the pressor effect of phenylephrine during isoflurane anesthesia in monkeys.
    Journal of neurosurgical anesthesiology, 2010, Volume: 22, Issue:2

    Topics: Adrenergic alpha-Agonists; Anesthesia; Anesthetics, Inhalation; Animals; Blood Pressure; Carbon Diox

2010
Desflurane results in higher cerebral blood flow than sevoflurane or isoflurane at hypocapnia in pigs.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Blood Flow Velocity; Blood Pressure; Cerebrovascular Circulation;

2004
Nitrous oxide added to isoflurane increases brain artery blood flow and low frequency brain electrical activity.
    Journal of neurosurgical anesthesiology, 1995, Volume: 7, Issue:2

    Topics: Adult; Alpha Rhythm; Anesthesia, Inhalation; Beta Rhythm; Blood Flow Velocity; Blood Pressure; Carbo

1995
CSF, sagittal sinus, and jugular venous pressures during desflurane or isoflurane anesthesia in dogs.
    Journal of neurosurgical anesthesiology, 1994, Volume: 6, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Pressure; Carbon Dioxide; Central Ve

1994
The effect of acute hypocapnia on local cerebral blood flow during middle cerebral artery occlusion in isoflurane anesthetized rats.
    Anesthesiology, 1993, Volume: 78, Issue:1

    Topics: Acute Disease; Anesthesia, Inhalation; Animals; Arterial Occlusive Diseases; Cerebral Arterial Disea

1993
Volatile anaesthetics attenuate hypocapnia-induced constriction in isolated dog cerebral arteries.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Basilar Artery; Cerebral Arteries; Cerebrovascular Circulation; Do

1997
Cerebral normoxia in the rhesus monkey during isoflurane- or propofol-induced hypotension and hypocapnia, despite disparate blood-flow patterns. A positron emission tomography study.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:8

    Topics: Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; B

1997
Effects of volatile anesthetics on respiratory activity and chemosensitivity in the isolated brainstem-spinal cord of the newborn rat.
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1998, Volume: 73, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Bicuculline; Brain Stem; Dose-Response Relations

1998
-The effect of desflurane on cerebral blood flow velocity and cerebrovascular reactivity to CO2 in children-.
    Annales francaises d'anesthesie et de reanimation, 1998, Volume: 17, Issue:3

    Topics: Adult; Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Flow Velocity;

1998
Effects of nitrous oxide on cerebral haemodynamics and metabolism during isoflurane anaesthesia in man.
    Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:1

    Topics: Adult; Anesthesia, Inhalation; Brain; Carbon Dioxide; Cerebrovascular Circulation; Electroencephalog

1992
Effects of hypocapnia on canine spinal, subcortical, and cortical somatosensory-evoked potentials during isoflurane anesthesia.
    Journal of clinical monitoring, 1992, Volume: 8, Issue:2

    Topics: Analysis of Variance; Anesthesia, Inhalation; Animals; Carbon Dioxide; Cerebral Cortex; Dogs; Electr

1992