Page last updated: 2024-10-29

isoflurane and Hypercapnia

isoflurane has been researched along with Hypercapnia in 48 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.

Research Excerpts

ExcerptRelevanceReference
"To test the hypothesis that hypercapnia produced by hypoventilation before desflurane cessation shortens emergence time from general anaesthesia (primary hypothesis) and reduces undesirable cardiorespiratory events."9.41Hypercapnia versus normocapnia for emergence from desflurane anaesthesia: Single-blinded randomised controlled study. ( Hasegawa, M; Isono, S; Kitamura, Y; Nozaki-Taguchi, N; Okazaki, J; Saito, K; Sato, Y; Shinohara, A; Yoshimura, A, 2021)
"Three-day-long isoflurane treatment resolved drug-refractory bronchospasm, decreased airway pressure and improved gas exchange, even at a low end-tidal concentration (0."7.83Isoflurane rescue therapy for bronchospasm reduces intracranial pressure in a patient with traumatic brain injury. ( Dolenc, S; Gradisek, P, 2016)
"Standard treatments against severe acute asthma can be insufficient and need salvation treatments, such as isoflurane delivery."7.77[Severe acute asthma: isoflurane administration via AnaConDa™, is it safe?]. ( Badin, J; Chaillan, M; Kerforne, T; Pinsard, M; Voultoury, J, 2011)
"To evaluate the effects of induced hypercapnia on the electroretinogram (ERG) in beagle dogs anaesthetized with isoflurane and sevoflurane."7.76Effects of hypercapnia on the electroretinogram in sevoflurane and isoflurane anaesthetized dogs. ( Alvarez Vazquez, JC; Gonzalez Cantalapiedra, A; Rosolen, SG; Varela Lopez, O, 2010)
"We evaluated the differences in emergence time in 20 surgical patients undergoing 1 MAC of isoflurane under mild hypocapnia (ETco2 approximately 28 mmHg) and mild hypercapnia (ETco2 approximately 55 mmHg)."7.74Hypercapnic hyperventilation shortens emergence time from isoflurane anesthesia. ( Gopalakrishnan, NA; Orr, JA; Sakata, DJ; Westenskow, DR; White, JL, 2007)
"Hypercapnia with hyperventilation shortens the time between turning off the vaporizer (1 MAC) and when patients open their eyes after isoflurane anesthesia by 62%."7.74Rapid recovery from sevoflurane and desflurane with hypercapnia and hyperventilation. ( Gopalakrishnan, NA; Orr, JA; Sakata, DJ; Westenskow, DR; White, JL, 2007)
"The purpose of the present study was to quantify the inhibitory effect of inhaled halothane and isoflurane on acute hypercapnia-induced responses of capacitance-regulating veins and related cardiovascular variables in response to sequential 40-s periods of 5%, 10%, 15%, and 20% inspired CO2 (FICO2)."7.69Effect of halothane and isoflurane on in situ diameter responses of small mesenteric veins to acute graded hypercapnia. ( Bosnjak, ZJ; Kampine, JP; Stadnicka, A; Stekiel, TA; Stekiel, WJ; Tominaga, M, 1996)
"At low dose, the halogenated anesthetic agents halothane, isoflurane, and enflurane depress the ventilatory response to isocapnic hypoxia in humans."7.69Ventilatory response to hypoxia in humans. Influences of subanesthetic desflurane. ( Berkenbosch, A; Dahan, A; Sarton, E; Teppema, L; van den Elsen, M; van Kleef, J, 1996)
"To test the hypothesis that hypercapnia produced by hypoventilation before desflurane cessation shortens emergence time from general anaesthesia (primary hypothesis) and reduces undesirable cardiorespiratory events."5.41Hypercapnia versus normocapnia for emergence from desflurane anaesthesia: Single-blinded randomised controlled study. ( Hasegawa, M; Isono, S; Kitamura, Y; Nozaki-Taguchi, N; Okazaki, J; Saito, K; Sato, Y; Shinohara, A; Yoshimura, A, 2021)
"Isoflurane inhalation was commenced in preparation for extracorporeal circulation, to reduce the hypercapnia."5.40Treatment of life-threatening hypercapnia with isoflurane in an infant with status asthmaticus. ( Goto, K; Imaizumi, H; Kimijima, T; Masuda, Y; Tatsumi, H; Yamakage, M; Yoshida, S, 2014)
"We evaluated the effectiveness of intentional hypercapnia against hypotension after induction of anaesthesia with thiopental and isoflurane (TI) or propofol (P)."5.11Effect of hypercapnia on arterial hypotension after induction of anaesthesia. ( Enoki, T; Fukuda, K; Nomura, R; Shinomura, T; Tsuchiya, N, 2005)
" Various anesthetic conditions embracing numerous anesthetic depths evoked by different concentrations of isoflurane (ISO) and different degrees of hypercapnia under a constant stimulus were investigated."3.91Anesthesia differentially modulates neuronal and vascular contributions to the BOLD signal. ( Albers, F; Budde, T; Datunashvili, M; Faber, C; Just, N; van Alst, TM; Wachsmuth, L, 2019)
"Three-day-long isoflurane treatment resolved drug-refractory bronchospasm, decreased airway pressure and improved gas exchange, even at a low end-tidal concentration (0."3.83Isoflurane rescue therapy for bronchospasm reduces intracranial pressure in a patient with traumatic brain injury. ( Dolenc, S; Gradisek, P, 2016)
"Compared to isoflurane, sevoflurane caused greater hypoventilation and was associated with longer times until standing recovery."3.78Effects of hypercapnic hyperpnea on recovery from isoflurane or sevoflurane anesthesia in horses. ( Brosnan, RJ; Escobar, A; Steffey, EP, 2012)
"Standard treatments against severe acute asthma can be insufficient and need salvation treatments, such as isoflurane delivery."3.77[Severe acute asthma: isoflurane administration via AnaConDa™, is it safe?]. ( Badin, J; Chaillan, M; Kerforne, T; Pinsard, M; Voultoury, J, 2011)
"To evaluate the effects of induced hypercapnia on the electroretinogram (ERG) in beagle dogs anaesthetized with isoflurane and sevoflurane."3.76Effects of hypercapnia on the electroretinogram in sevoflurane and isoflurane anaesthetized dogs. ( Alvarez Vazquez, JC; Gonzalez Cantalapiedra, A; Rosolen, SG; Varela Lopez, O, 2010)
" Static changes of CBF were achieved using different anesthetics (chloral hydrate, CH; alpha-chloralose, alphaCS; and isoflurane, IF) with alphaCS causing larger decreases in CBF than CH and IF; dynamic changes were achieved by inducing transient hypercapnia (5% CO(2) in 40% O(2) and 55% N(2))."3.75Body and brain temperature coupling: the critical role of cerebral blood flow. ( Ackerman, JJ; Yablonskiy, DA; Zhu, M, 2009)
"We evaluated the differences in emergence time in 20 surgical patients undergoing 1 MAC of isoflurane under mild hypocapnia (ETco2 approximately 28 mmHg) and mild hypercapnia (ETco2 approximately 55 mmHg)."3.74Hypercapnic hyperventilation shortens emergence time from isoflurane anesthesia. ( Gopalakrishnan, NA; Orr, JA; Sakata, DJ; Westenskow, DR; White, JL, 2007)
"Hypercapnia with hyperventilation shortens the time between turning off the vaporizer (1 MAC) and when patients open their eyes after isoflurane anesthesia by 62%."3.74Rapid recovery from sevoflurane and desflurane with hypercapnia and hyperventilation. ( Gopalakrishnan, NA; Orr, JA; Sakata, DJ; Westenskow, DR; White, JL, 2007)
" We assessed the effects of dexmedetomidine (DEX), a highly selective alpha 2-adrenergic agonist, on the cerebrovascular response to hypercapnia in dogs anesthetized with either pentobarbital (PENTO) or isoflurane (ISO), drugs which produce different levels of CBF at a similar level of cerebral oxygen consumption (CMRO2)."3.69Alpha 2-adrenergic agonist effects on normocapnic and hypercapnic cerebral blood flow in the dog are anesthetic dependent. ( Fale, A; Kirsch, JR; McPherson, RW, 1994)
"The purpose of the present study was to quantify the inhibitory effect of inhaled halothane and isoflurane on acute hypercapnia-induced responses of capacitance-regulating veins and related cardiovascular variables in response to sequential 40-s periods of 5%, 10%, 15%, and 20% inspired CO2 (FICO2)."3.69Effect of halothane and isoflurane on in situ diameter responses of small mesenteric veins to acute graded hypercapnia. ( Bosnjak, ZJ; Kampine, JP; Stadnicka, A; Stekiel, TA; Stekiel, WJ; Tominaga, M, 1996)
"At low dose, the halogenated anesthetic agents halothane, isoflurane, and enflurane depress the ventilatory response to isocapnic hypoxia in humans."3.69Ventilatory response to hypoxia in humans. Influences of subanesthetic desflurane. ( Berkenbosch, A; Dahan, A; Sarton, E; Teppema, L; van den Elsen, M; van Kleef, J, 1996)
"The ventilatory responses to isocapnic hypoxia and hypercapnia were studied in six dogs each with a tracheostomy, awake and during anaesthesia with halothane, enflurane and isoflurane (1-2."3.65Depression of hypoxic ventilatory response by halothane, enflurane and isoflurane in dogs. ( Cohen, PJ; Hirshman, CA; McCullough, RE; Weil, JV, 1977)
"Targeted temperature management after cardiac arrest requires deep sedation to prevent shivering and discomfort."1.46Isoflurane Sedation on the ICU in Cardiac Arrest Patients Treated With Targeted Temperature Management: An Observational Propensity-Matched Study. ( Engels, M; Jörres, A; Krannich, A; Kruse, J; Leithner, C; Nee, J; Petzinka, V; Schröder, T; Storm, C, 2017)
"Isoflurane inhalation was commenced in preparation for extracorporeal circulation, to reduce the hypercapnia."1.40Treatment of life-threatening hypercapnia with isoflurane in an infant with status asthmaticus. ( Goto, K; Imaizumi, H; Kimijima, T; Masuda, Y; Tatsumi, H; Yamakage, M; Yoshida, S, 2014)
"Isoflurane anesthesia was used here to study CBF regulation during repetitive scanning in rats."1.35Longitudinal MRI studies in the isoflurane-anesthetized rat: long-term effects of a short hypoxic episode on regulation of cerebral blood flow as assessed by pulsed arterial spin labelling. ( Wegener, S; Wong, EC, 2008)
"Therefore, a genetic predisposition to a blunted carbon dioxide response represents a susceptibility factor that interacts with hypercapnoeic hypoventilation during maintenance of anaesthesia and in the emergence from anaesthesia, regardless of the agent used."1.32Influence of volatile anaesthetics on hypercapnoeic ventilatory responses in mice with blunted respiratory drive. ( Brown, RH; Groeben, H; Meier, S; Mitzner, W; Tankersley, CG, 2004)
"Dexmedetomidine (DMED) is a novel alpha 2 adrenergic agonist that has been shown to have potent analgesic and anesthetic sparing effects."1.28Ventilatory effects of dexmedetomidine, atipamezole, and isoflurane in dogs. ( Abdul-Rasool, I; Bloor, B; Hadlock, S; Hsieh, J; Kobayashi, D; Nguyen, D; Singer, F; Ward, D, 1992)
"Isoflurane anesthesia was also studied in a second group of rats to see if a different general anesthetic agent would cause the same effects that halothane causes."1.27Cerebral intracellular ADP concentrations during hypercarbia: an in vivo 31P nuclear magnetic resonance study in rats. ( González-Méndez, R; Hamilton, WK; James, TL; Litt, L; Murphy-Boesch, J; Rampil, IJ; Severinghaus, JW; Shuleshko, J, 1986)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19903 (6.25)18.7374
1990's15 (31.25)18.2507
2000's12 (25.00)29.6817
2010's17 (35.42)24.3611
2020's1 (2.08)2.80

Authors

AuthorsStudies
Shinohara, A1
Nozaki-Taguchi, N1
Yoshimura, A1
Hasegawa, M1
Saito, K1
Okazaki, J1
Kitamura, Y1
Sato, Y1
Isono, S1
van Alst, TM1
Wachsmuth, L1
Datunashvili, M1
Albers, F1
Just, N1
Budde, T1
Faber, C1
Lee, S1
Masuda, Y1
Tatsumi, H1
Goto, K1
Imaizumi, H1
Yoshida, S1
Kimijima, T1
Yamakage, M1
Iwata, K1
Iida, H1
Iida, M1
Fukuoka, N1
Kito, K1
Tanabe, K1
Kim, SY1
Chae, DW1
Chun, YM1
Jeong, KH1
Park, K1
Han, DW1
Gradisek, P1
Dolenc, S1
Low, LA1
Bauer, LC1
Klaunberg, BA1
Jungbauer, S1
Buehler, PK1
Neubauer, J1
Haas, C1
Heitzmann, D1
Tegtmeier, I1
Sterner, C1
Barhanin, J1
Georgieff, M1
Warth, R1
Thomas, J1
Krannich, A1
Leithner, C1
Engels, M1
Nee, J1
Petzinka, V1
Schröder, T1
Jörres, A1
Kruse, J1
Storm, C1
Zhu, M1
Ackerman, JJ1
Yablonskiy, DA1
Rioja, E1
Kerr, CL1
McDonell, WN2
Dobson, H1
Konyer, NB1
Poma, R1
Noseworthy, MD1
Varela Lopez, O1
Alvarez Vazquez, JC1
Gonzalez Cantalapiedra, A1
Rosolen, SG1
Zheng, B1
Lee, PT1
Golay, X1
Wey, HY1
Wang, DJ1
Duong, TQ4
Chaillan, M1
Badin, J1
Kerforne, T1
Voultoury, J1
Pinsard, M1
Pang, DS1
Panizzi, L1
Paterson, JM1
Drummond, GB1
Dhonneur, G1
Kirov, K1
Duvaldestin, P1
Brosnan, RJ1
Steffey, EP1
Escobar, A1
Luginbuehl, IA1
Karsli, C1
Bissonnette, B1
Groeben, H2
Meier, S2
Tankersley, CG1
Mitzner, W1
Brown, RH1
Nair, G1
Enoki, T1
Tsuchiya, N1
Shinomura, T1
Nomura, R1
Fukuda, K1
Sakata, DJ3
Gopalakrishnan, NA3
Orr, JA3
White, JL2
Westenskow, DR3
McJames, S1
Li, Y1
Cheng, H1
Hübner, CA1
Peters, J1
Bingmann, D1
Wiemann, M1
Wegener, S1
Wong, EC1
Kalman, SH1
Johnson, A1
Cornick-Seahorn, JL1
Mikota, SK1
Schaeffer, DO1
Ranglack, GS1
Boatright, SB1
Fale, A1
Kirsch, JR1
McPherson, RW1
King, BS1
Rampil, IJ2
Koenig, HM1
Pelagalli, FM1
Piccini, M1
Tateyama, T1
Asada, M1
Suzuki, H1
Hashimoto, K1
Okazaki, K1
Okutsu, Y1
Khanna, AK1
Dyson, DH1
Taylor, PM1
Stekiel, TA1
Stekiel, WJ1
Tominaga, M1
Stadnicka, A1
Bosnjak, ZJ1
Kampine, JP1
Dahan, A2
Sarton, E2
van den Elsen, M2
van Kleef, J1
Teppema, L2
Berkenbosch, A2
Sollevi, A1
Lindahl, SG1
Otsuka, H1
Einarsson, SG1
Cerne, A1
Bengtsson, A1
Stenqvist, O1
Bengtson, JP1
Iadecola, C1
Kim, SG1
Hirshman, CA1
McCullough, RE1
Cohen, PJ1
Weil, JV1
Nguyen, D1
Abdul-Rasool, I1
Ward, D1
Hsieh, J1
Kobayashi, D1
Hadlock, S1
Singer, F1
Bloor, B1
Wattwil, LM1
Olsson, JG1
Litt, L1
González-Méndez, R1
Severinghaus, JW1
Hamilton, WK1
Shuleshko, J1
Murphy-Boesch, J1
James, TL1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05327296]Phase 3235 participants (Anticipated)Interventional2022-06-30Recruiting
A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05312385]Phase 3235 participants (Anticipated)Interventional2022-04-28Recruiting
Effect of Fresh Gas Flow on Emergence Time in the Patients Undergoing Transurethral Resection of Bladder Tumor: A Randomized Controlled Clinical Trial[NCT05376631]54 participants (Actual)Interventional2022-05-20Completed
The Association of CPAP Compliance and Nocturnal Hypoxemia in the Perioperative Period[NCT02796846]158 participants (Actual)Observational2015-06-30Completed
Evaluation of Screening Tools for OSA in Hospitalized Medical Patients: A Validation Study[NCT01340781]110 participants (Actual)Observational2012-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for isoflurane and Hypercapnia

ArticleYear
Hypercapnia versus normocapnia for emergence from desflurane anaesthesia: Single-blinded randomised controlled study.
    European journal of anaesthesiology, 2021, 11-01, Volume: 38, Issue:11

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Desflurane; Huma

2021
Cerebrovascular reactivity to carbon dioxide is preserved during hypocapnia in children anesthetized with 1.0 MAC, but not with 1.5 MAC desflurane.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2003, Volume: 50, Issue:2

    Topics: Adolescent; Anesthesia, Inhalation; Anesthetics, Inhalation; Carbon Dioxide; Cerebrovascular Circula

2003
Effect of hypercapnia on arterial hypotension after induction of anaesthesia.
    Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intraveno

2005
Influence of halothane-diethyl-ether azeotrope and isoflurane on ventilation. Re-evaluation of an obsolete drug.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Bone and Bones; Carbon Dioxid

1995
Influence of 0.1 minimum alveolar concentration of sevoflurane, desflurane and isoflurane on dynamic ventilatory response to hypercapnia in humans.
    British journal of anaesthesia, 1998, Volume: 80, Issue:2

    Topics: Adult; Anesthetics, Inhalation; Conscious Sedation; Desflurane; Drug Administration Schedule; Female

1998
Respiration during emergence from anaesthesia with desflurane/N2O vs. desflurane/air for gynaecological laparoscopy.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:10

    Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Carbon Dio

1998

Other Studies

42 other studies available for isoflurane and Hypercapnia

ArticleYear
Anesthesia differentially modulates neuronal and vascular contributions to the BOLD signal.
    NeuroImage, 2019, 07-15, Volume: 195

    Topics: Anesthetics, Inhalation; Animals; Brain; Female; Hypercapnia; Isoflurane; Magnetic Resonance Imaging

2019
Can desflurane be an alternative to sevoflurane in neuroanesthesia?
    Korean journal of anesthesiology, 2019, Volume: 72, Issue:3

    Topics: Anesthesia; Animals; Desflurane; Hypercapnia; Isoflurane; Rats; Sevoflurane

2019
Treatment of life-threatening hypercapnia with isoflurane in an infant with status asthmaticus.
    Journal of anesthesia, 2014, Volume: 28, Issue:4

    Topics: Anesthetics, Inhalation; Asthma; Carbon Dioxide; Coma; Female; Humans; Hypercapnia; Infant; Isoflura

2014
Effects of topical and intravenous JM-1232(-) infusion on cerebrovascular reactivity in rats.
    Journal of anesthesia, 2015, Volume: 29, Issue:5

    Topics: Administration, Topical; Animals; Arterioles; Hypercapnia; Infusions, Intravenous; Isoflurane; Isoin

2015
Modelling of the Effect of End-Tidal Carbon Dioxide on Cerebral Oxygen Saturation in Beach Chair Position under General Anaesthesia.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Arthroscopy; Carbon Dioxide; Desflurane; Diabet

2016
Isoflurane rescue therapy for bronchospasm reduces intracranial pressure in a patient with traumatic brain injury.
    Brain injury, 2016, Volume: 30, Issue:8

    Topics: Adult; Anesthetics, Inhalation; Brain Injuries, Traumatic; Bronchial Spasm; Cerebrovascular Circulat

2016
Comparing the Effects of Isoflurane and Alpha Chloralose upon Mouse Physiology.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Anesthesia; Anesthetics; Animals; Arteries; Blood Gas Analysis; Body Temperature; Brain; Brain Mappi

2016
Sex-dependent differences in the in vivo respiratory phenotype of the TASK-1 potassium channel knockout mouse.
    Respiratory physiology & neurobiology, 2017, Volume: 245

    Topics: Aging; Anesthetics, Inhalation; Animals; Animals, Newborn; Cohort Studies; Female; Humans; Hypercapn

2017
Isoflurane Sedation on the ICU in Cardiac Arrest Patients Treated With Targeted Temperature Management: An Observational Propensity-Matched Study.
    Critical care medicine, 2017, Volume: 45, Issue:4

    Topics: Administration, Inhalation; Administration, Intravenous; Aged; Anesthetics, Inhalation; Anesthetics,

2017
Isoflurane Sedation on the ICU in Cardiac Arrest Patients Treated With Targeted Temperature Management: An Observational Propensity-Matched Study.
    Critical care medicine, 2017, Volume: 45, Issue:4

    Topics: Administration, Inhalation; Administration, Intravenous; Aged; Anesthetics, Inhalation; Anesthetics,

2017
Isoflurane Sedation on the ICU in Cardiac Arrest Patients Treated With Targeted Temperature Management: An Observational Propensity-Matched Study.
    Critical care medicine, 2017, Volume: 45, Issue:4

    Topics: Administration, Inhalation; Administration, Intravenous; Aged; Anesthetics, Inhalation; Anesthetics,

2017
Isoflurane Sedation on the ICU in Cardiac Arrest Patients Treated With Targeted Temperature Management: An Observational Propensity-Matched Study.
    Critical care medicine, 2017, Volume: 45, Issue:4

    Topics: Administration, Inhalation; Administration, Intravenous; Aged; Anesthetics, Inhalation; Anesthetics,

2017
Body and brain temperature coupling: the critical role of cerebral blood flow.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2009, Volume: 179, Issue:6

    Topics: Acid-Base Equilibrium; Algorithms; Anesthesia; Animals; Blood Pressure; Body Temperature; Brain; Car

2009
Effects of hypercapnia, hypocapnia, and hyperoxemia on blood oxygenation level-dependent signal intensity determined by use of susceptibility-weighted magnetic resonance imaging in isoflurane-anesthetized dogs.
    American journal of veterinary research, 2010, Volume: 71, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Brain; Dogs; Hypercapnia; Hyperoxia; Hypocapnia; Isoflurane; Magne

2010
Effects of hypercapnia on the electroretinogram in sevoflurane and isoflurane anaesthetized dogs.
    Documenta ophthalmologica. Advances in ophthalmology, 2010, Volume: 121, Issue:1

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Dark Adaptation; Dogs; Electroretinography; Female; Hy

2010
High-sensitivity cerebral perfusion mapping in mice by kbGRASE-FAIR at 9.4 T.
    NMR in biomedicine, 2010, Volume: 23, Issue:9

    Topics: Anesthetics, Inhalation; Animals; Brain; Brain Mapping; Cerebrovascular Circulation; Echo-Planar Ima

2010
Baseline CBF, and BOLD, CBF, and CMRO2 fMRI of visual and vibrotactile stimulations in baboons.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2011, Volume: 31, Issue:2

    Topics: Algorithms; Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Brain; Calibrat

2011
[Severe acute asthma: isoflurane administration via AnaConDa™, is it safe?].
    Annales francaises d'anesthesie et de reanimation, 2011, Volume: 30, Issue:1

    Topics: Acute Disease; Anesthesiology; Anesthetics, Inhalation; Asthma; Carbon Dioxide; Humans; Hypercapnia;

2011
Successful treatment of hyperkalaemic periodic paralysis in a horse during isoflurane anaesthesia.
    Veterinary anaesthesia and analgesia, 2011, Volume: 38, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Calcium Gluconate; Fluid Therapy; Glucose; Horse Diseases; Horses;

2011
Effects of airway occlusion on breathing muscle electromyogram signals, during isoflurane anaesthesia, with and without the effects of fentanyl and hypercapnia.
    British journal of anaesthesia, 2011, Volume: 107, Issue:6

    Topics: Abdominal Muscles; Adult; Aged; Airway Obstruction; Analgesics, Opioid; Anesthetics, Inhalation; Car

2011
Effects of hypercapnic hyperpnea on recovery from isoflurane or sevoflurane anesthesia in horses.
    Veterinary anaesthesia and analgesia, 2012, Volume: 39, Issue:4

    Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Carbon Dioxide

2012
Influence of volatile anaesthetics on hypercapnoeic ventilatory responses in mice with blunted respiratory drive.
    British journal of anaesthesia, 2004, Volume: 92, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Desflurane; Genetic Predisposition to Disease; Hypercapnia; Isoflu

2004
Echo-planar BOLD fMRI of mice on a narrow-bore 9.4 T magnet.
    Magnetic resonance in medicine, 2004, Volume: 52, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Echo-Planar Imaging; Electric Stimulation; Feasibility Studies; Hi

2004
Hypercapnic hyperventilation shortens emergence time from isoflurane anesthesia.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:3

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesiology; Carbon Dioxide; Female; H

2007
Hypercapnia shortens emergence time from inhaled anesthesia in pigs.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:4

    Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Carbon Dioxide

2007
Rapid recovery from sevoflurane and desflurane with hypercapnia and hyperventilation.
    Anesthesia and analgesia, 2007, Volume: 105, Issue:1

    Topics: Adult; Anesthesia Recovery Period; Desflurane; Female; Humans; Hypercapnia; Hyperventilation; Isoflu

2007
Blood-flow magnetic resonance imaging of the retina.
    NeuroImage, 2008, Feb-15, Volume: 39, Issue:4

    Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Artifacts; Data Interpretation, Statis

2008
Expression of anion exchanger 3 influences respiratory rate in awake and isoflurane anesthetized mice.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58 Suppl 5, Issue:Pt 1

    Topics: Anesthetics, Inhalation; Animals; Antiporters; Dose-Response Relationship, Drug; Hypercapnia; Isoflu

2007
Longitudinal MRI studies in the isoflurane-anesthetized rat: long-term effects of a short hypoxic episode on regulation of cerebral blood flow as assessed by pulsed arterial spin labelling.
    NMR in biomedicine, 2008, Volume: 21, Issue:7

    Topics: Anesthesia; Animals; Arteries; Blood Gas Analysis; Brain Mapping; Cerebrovascular Circulation; Hyper

2008
Isoflurane anesthesia in a rhinoceros.
    Journal of the American Veterinary Medical Association, 1995, Feb-15, Volume: 206, Issue:4

    Topics: Anesthesia, General; Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Creatine Kinase;

1995
Alpha 2-adrenergic agonist effects on normocapnic and hypercapnic cerebral blood flow in the dog are anesthetic dependent.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Cerebrovascular Circulatio

1994
Anesthetic depression of spinal motor neurons may contribute to lack of movement in response to noxious stimuli.
    Anesthesiology, 1994, Volume: 81, Issue:6

    Topics: Action Potentials; Animals; Blood Pressure; Carbon Dioxide; Dose-Response Relationship, Drug; Electr

1994
What's up with the new volatile anesthetics, desflurane and sevoflurane, for neurosurgical patients?
    Journal of neurosurgical anesthesiology, 1994, Volume: 6, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Blood Volume; Brain; Brain Injuries; Carbon Dioxide; Cerebrospinal

1994
[Carbon dioxide measurement in neuroanesthesia].
    Minerva anestesiologica, 1993, Volume: 59, Issue:11

    Topics: Adult; Aged; Anesthesia, General; Anesthesia, Inhalation; Blood Gas Analysis; Body Temperature; Carb

1993
[Effect of 10% carbon dioxide on regional myocardial tissue oxygen tension and myocardial metabolism].
    Masui. The Japanese journal of anesthesiology, 1994, Volume: 43, Issue:1

    Topics: Anesthesia, Inhalation; Animals; Carbon Dioxide; Coronary Circulation; Dogs; Hypercapnia; Isoflurane

1994
Cardiopulmonary effects of hypercapnia during controlled intermittent positive pressure ventilation in the horse.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1995, Volume: 59, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Carbon Dioxide; Dose-Response Relationship, Drug; Female; Hemodyna

1995
Effect of halothane and isoflurane on in situ diameter responses of small mesenteric veins to acute graded hypercapnia.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:2

    Topics: Acute Disease; Anesthetics, Inhalation; Animals; Blood Pressure; Bradycardia; Halothane; Heart Rate;

1996
Ventilatory response to hypoxia in humans. Influences of subanesthetic desflurane.
    Anesthesiology, 1996, Volume: 85, Issue:1

    Topics: Adult; Anesthetics, Inhalation; Carbon Dioxide; Desflurane; Humans; Hypercapnia; Hypoxia; Isoflurane

1996
Hypoxic and hypercapnic ventilatory responses during isoflurane sedation and anaesthesia in women.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:7

    Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Carbon Dioxide; Conscious Sedation; Female;

1995
Hypoxic and hypercapnic ventilatory responses during isoflurane sedation and anaesthesia in women.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:7

    Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Carbon Dioxide; Conscious Sedation; Female;

1995
Hypoxic and hypercapnic ventilatory responses during isoflurane sedation and anaesthesia in women.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:7

    Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Carbon Dioxide; Conscious Sedation; Female;

1995
Hypoxic and hypercapnic ventilatory responses during isoflurane sedation and anaesthesia in women.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:7

    Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Carbon Dioxide; Conscious Sedation; Female;

1995
Effects of volatile anesthetics on respiratory activity and chemosensitivity in the isolated brainstem-spinal cord of the newborn rat.
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1998, Volume: 73, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Bicuculline; Brain Stem; Dose-Response Relations

1998
Effect of hyperoxia, hypercapnia, and hypoxia on cerebral interstitial oxygen tension and cerebral blood flow.
    Magnetic resonance in medicine, 2001, Volume: 45, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Brain; Cerebrovascular Circulation; Fluorocarbons; Hypercapnia; Hy

2001
Depression of hypoxic ventilatory response by halothane, enflurane and isoflurane in dogs.
    British journal of anaesthesia, 1977, Volume: 49, Issue:10

    Topics: Anesthesia; Animals; Carbon Dioxide; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; E

1977
Ventilatory effects of dexmedetomidine, atipamezole, and isoflurane in dogs.
    Anesthesiology, 1992, Volume: 76, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dogs; Dose-Response Relationship,

1992
Circulatory effects of isoflurane during acute hypercapnia.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:12

    Topics: Acute Disease; Aged; Anesthesia, General; Hemodynamics; Humans; Hypercapnia; Isoflurane; Middle Aged

1987
Cerebral intracellular ADP concentrations during hypercarbia: an in vivo 31P nuclear magnetic resonance study in rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1986, Volume: 6, Issue:3

    Topics: Adenosine Diphosphate; Anesthesia, General; Animals; Brain; Electroencephalography; Halothane; Hyper

1986