isoflurane has been researched along with Endotoxemia in 12 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effects of emulsified isoflurane preconditioning on LPS-induced acute lung injury in rats." | 7.79 | [Effects of emulsified isoflurane preconditioning on LPS-induced acute lung injury in rats]. ( Liu, J; Xu, WM; Zhang, JY, 2013) |
| "Endotoxemia increases both the hypnotic and antinociceptive effects of isoflurane, in contrast to hemorrhagic shock, and the extent of these alterations increases with progression of endotoxemia." | 7.76 | The influence of endotoxemia on the electroencephalographic and antinociceptive effects of isoflurane in a swine model. ( Kurita, T; Morita, K; Sato, S; Takata, K; Uraoka, M, 2010) |
| "The effects of isoflurane pretreatment on pulmonary proinflammatory cytokines and survival in severe endotoxin-induced acute lung injury (ALI) have not been studied systemically." | 7.75 | Isoflurane preconditioning ameliorates endotoxin-induced acute lung injury and mortality in rats. ( Jiang, H; Li, QF; Sun, Y; Xu, H; Zhu, YS, 2009) |
| " Isoflurane has been shown to attenuate the response to inflammatory stimuli such as lipopolysaccharide (LPS) when administered before induction of endotoxemia." | 7.74 | Isoflurane inhalation after induction of endotoxemia in rats attenuates the systemic cytokine response. ( Betz, C; Boost, KA; Flondor, M; Hofstetter, C; Homann, M; Zwissler, B, 2008) |
| "Isoflurane is a common anesthetic agent used in human surgery and in animal models of sepsis." | 5.37 | The effects of isoflurane anesthesia and mechanical ventilation on renal function during endotoxemia. ( Eriksson, S; Fenhammar, J; Frithiof, R; Hjelmqvist, H; Lindbom, L; Rundgren, M; Soehnlein, O, 2011) |
| "Ketamine has hepatoprotective effects, while isoflurane does not." | 5.33 | Ketamine attenuates liver injury attributed to endotoxemia: role of cyclooxygenase-2. ( Gonzalez, EA; Helmer, KS; Mercer, DW; Robinson, EK; Suliburk, JW, 2005) |
| "To investigate the effects of emulsified isoflurane preconditioning on LPS-induced acute lung injury in rats." | 3.79 | [Effects of emulsified isoflurane preconditioning on LPS-induced acute lung injury in rats]. ( Liu, J; Xu, WM; Zhang, JY, 2013) |
| "Endotoxemia increases both the hypnotic and antinociceptive effects of isoflurane, in contrast to hemorrhagic shock, and the extent of these alterations increases with progression of endotoxemia." | 3.76 | The influence of endotoxemia on the electroencephalographic and antinociceptive effects of isoflurane in a swine model. ( Kurita, T; Morita, K; Sato, S; Takata, K; Uraoka, M, 2010) |
| "The effects of isoflurane pretreatment on pulmonary proinflammatory cytokines and survival in severe endotoxin-induced acute lung injury (ALI) have not been studied systemically." | 3.75 | Isoflurane preconditioning ameliorates endotoxin-induced acute lung injury and mortality in rats. ( Jiang, H; Li, QF; Sun, Y; Xu, H; Zhu, YS, 2009) |
| "Volatile anesthetics such as isoflurane have been shown to offer anti-inflammatory effects during experimental endotoxemia whereas the alpha-adrenergic vasopressor norepinephrine exhibits proinflammatory properties on systemic cytokine release under the same conditions." | 3.74 | Norepinephrine and vasopressin counteract anti-inflammatory effects of isoflurane in endotoxemic rats. ( Boost, KA; Flondor, M; Hoegl, S; Hofstetter, C; Muhl, H; Pfeilschifter, J; Scheller, B; Zwissler, B, 2007) |
| "During low-dose endotoxemia, arteriolar vasodilation under isoflurane was nearly abolished (P < ." | 3.71 | Effects of isoflurane, enflurane, and halothane on skeletal muscle microcirculation in the endotoxemic rat. ( Klotz, KF; Pörksen, M; Schumacher, J, 2001) |
| "Isoflurane is a common anesthetic agent used in human surgery and in animal models of sepsis." | 1.37 | The effects of isoflurane anesthesia and mechanical ventilation on renal function during endotoxemia. ( Eriksson, S; Fenhammar, J; Frithiof, R; Hjelmqvist, H; Lindbom, L; Rundgren, M; Soehnlein, O, 2011) |
| "Ketamine has hepatoprotective effects, while isoflurane does not." | 1.33 | Ketamine attenuates liver injury attributed to endotoxemia: role of cyclooxygenase-2. ( Gonzalez, EA; Helmer, KS; Mercer, DW; Robinson, EK; Suliburk, JW, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (75.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, WM | 1 |
| Zhang, JY | 1 |
| Liu, J | 1 |
| Li, QF | 1 |
| Zhu, YS | 1 |
| Jiang, H | 2 |
| Xu, H | 1 |
| Sun, Y | 1 |
| Kurita, T | 1 |
| Takata, K | 1 |
| Morita, K | 1 |
| Uraoka, M | 1 |
| Sato, S | 1 |
| Frithiof, R | 1 |
| Soehnlein, O | 1 |
| Eriksson, S | 1 |
| Fenhammar, J | 1 |
| Hjelmqvist, H | 1 |
| Lindbom, L | 1 |
| Rundgren, M | 1 |
| Hofstetter, C | 5 |
| Flondor, M | 5 |
| Boost, KA | 5 |
| Koehler, P | 1 |
| Bosmann, M | 1 |
| Pfeilschifter, J | 3 |
| Zwissler, B | 5 |
| Mühl, H | 3 |
| Suliburk, JW | 1 |
| Helmer, KS | 1 |
| Gonzalez, EA | 1 |
| Robinson, EK | 1 |
| Mercer, DW | 1 |
| Zhang, H | 1 |
| Xue, ZG | 1 |
| Betz, C | 2 |
| Homann, M | 2 |
| Muehl, H | 1 |
| Platacis, I | 1 |
| Stegewerth, K | 1 |
| Hoegl, S | 2 |
| Nguyen, T | 1 |
| Scheller, B | 1 |
| Schumacher, J | 1 |
| Pörksen, M | 1 |
| Klotz, KF | 1 |
12 other studies available for isoflurane and Endotoxemia
| Article | Year |
|---|---|
[Effects of emulsified isoflurane preconditioning on LPS-induced acute lung injury in rats].
Topics: Acute Lung Injury; Anesthetics, Inhalation; Animals; Endotoxemia; Ischemic Preconditioning; Isoflura | 2013 |
Isoflurane preconditioning ameliorates endotoxin-induced acute lung injury and mortality in rats.
Topics: Acid-Base Equilibrium; Acute Lung Injury; Animals; Cytoprotection; Disease Models, Animal; Endotoxem | 2009 |
The influence of endotoxemia on the electroencephalographic and antinociceptive effects of isoflurane in a swine model.
Topics: Analgesics; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Electroencephalography; Endoto | 2010 |
The effects of isoflurane anesthesia and mechanical ventilation on renal function during endotoxemia.
Topics: Anesthetics, Inhalation; Angiotensin II; Animals; Arginine Vasopressin; Cell Migration Assays, Leuko | 2011 |
A brief exposure to isoflurane (50 s) significantly impacts on plasma cytokine levels in endotoxemic rats.
Topics: Anesthetics, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Chemokine CCL5; Disease Models, Anim | 2005 |
Ketamine attenuates liver injury attributed to endotoxemia: role of cyclooxygenase-2.
Topics: Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhi | 2005 |
[The effect of posttreatment with isoflurane versus propofol on pulmonary alveolar capillary barrier in endotoxemic rats].
Topics: Animals; Blood-Air Barrier; Capillaries; Capillary Permeability; Endotoxemia; Isoflurane; Lipopolysa | 2005 |
Desflurane differentially affects the release of proinflammatory cytokines in plasma and bronchoalveolar fluid of endotoxemic rats.
Topics: Administration, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Desflurane; Endotoxemi | 2006 |
The beta-adrenoceptor antagonist propranolol counteracts anti-inflammatory effects of isoflurane in rat endotoxemia.
Topics: Adrenergic beta-Antagonists; Anesthetics, Inhalation; Animals; Anti-Inflammatory Agents; Blood Press | 2007 |
Isoflurane inhalation after induction of endotoxemia in rats attenuates the systemic cytokine response.
Topics: Anesthetics, Inhalation; Animals; Cells, Cultured; Cytokines; Endotoxemia; Immune System; Interleuki | 2008 |
Norepinephrine and vasopressin counteract anti-inflammatory effects of isoflurane in endotoxemic rats.
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Cells, Cultured; Cytokines; Drug Interactions; En | 2007 |
Effects of isoflurane, enflurane, and halothane on skeletal muscle microcirculation in the endotoxemic rat.
Topics: Anesthetics, Inhalation; Animals; Endotoxemia; Enflurane; Female; Halothane; Hemodynamics; Isofluran | 2001 |