isoflurane has been researched along with Down Syndrome in 1 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Additionally, trisomy 21 (P = 0." | 2.76 | Factors affecting the decision to defer endotracheal extubation after surgery for congenital heart disease: a prospective observational study. ( Bodian, C; Chakravarti, S; Hollinger, I; Hossain, S; Kin, N; Krol, M; Mittnacht, AJ; Nguyen, K; Srivastava, S; Weismann, C, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kin, N | 1 |
| Weismann, C | 1 |
| Srivastava, S | 1 |
| Chakravarti, S | 1 |
| Bodian, C | 1 |
| Hossain, S | 1 |
| Krol, M | 1 |
| Hollinger, I | 1 |
| Nguyen, K | 1 |
| Mittnacht, AJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of a Peri-Operative Continuous Bilateral Erector Spinae Plane (ESP) Continuous Catheter After Open Cardiac Surgery in Adults[NCT03901612] | Phase 4 | 0 participants (Actual) | Interventional | 2019-01-05 | Withdrawn (stopped due to covid and surgeon left) | ||
| Bilateral Erector Spinae Plane (ESP) Catheters Versus Single Shot ESP Block for Open Heart Surgery in Infants[NCT03593642] | 40 participants (Actual) | Interventional | 2018-10-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for isoflurane and Down Syndrome
| Article | Year |
|---|---|
Factors affecting the decision to defer endotracheal extubation after surgery for congenital heart disease: a prospective observational study.
Topics: Adolescent; Aging; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Dissociative; Anesthetic | 2011 |
Factors affecting the decision to defer endotracheal extubation after surgery for congenital heart disease: a prospective observational study.
Topics: Adolescent; Aging; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Dissociative; Anesthetic | 2011 |
Factors affecting the decision to defer endotracheal extubation after surgery for congenital heart disease: a prospective observational study.
Topics: Adolescent; Aging; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Dissociative; Anesthetic | 2011 |
Factors affecting the decision to defer endotracheal extubation after surgery for congenital heart disease: a prospective observational study.
Topics: Adolescent; Aging; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Dissociative; Anesthetic | 2011 |