isoflurane has been researched along with Disease Models, Animal in 310 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we compared sevoflurane and isoflurane with particular reference to their hemodynamic effects and ability to modify the effects of acute severe myocardial ischemia and reperfusion on ventricular arrhythmias and mortality in a porcine model of myocardial infarction." | 9.15 | Ventricular arrhythmias and mortality associated with isoflurane and sevoflurane in a porcine model of myocardial infarction. ( Ajenjo-Silverio, JM; Altónaga, JR; Cuellas-Ramón, C; de Prado, AP; Fernández-Vázquez, F; Gonzalo-Orden, JM; Orden, A; Regueiro-Purriños, M, 2011) |
| "We were able to determine the effects of the duration of anesthesia using isoflurane on the transcriptomes in the brains of rats at 24 h after tMCAO." | 8.31 | Isoflurane Anesthesia's Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model. ( Denisova, AE; Dergunova, LV; Filippenkov, IB; Gubsky, LV; Limborska, SA; Shpetko, YY; Stavchansky, VV, 2023) |
| " Here, we used a mouse chronic pain model to test the hypothesis that early exposure to the general anesthetic (GA) Isoflurane causes cellular and molecular alterations in dorsal spinal cord (DSC) and dorsal root ganglion (DRG) that produces a predisposition to neuropathic pain via an upregulation of the mammalian target of the rapamycin (mTOR) signaling pathway." | 8.31 | Effects of Early Exposure to Isoflurane on Susceptibility to Chronic Pain Are Mediated by Increased Neural Activity Due to Actions of the Mammalian Target of the Rapamycin Pathway. ( Dong, X; Guan, Y; Li, F; Li, Q; Mathena, RP; Mintz, CD, 2023) |
| "Isoflurane-anesthetized rats developed systemic acidosis that worsens with time during intracavernous pressure measurement, which results in a significant decrease in the maximum intracavernous pressure value, intracavernous pressure/mean arterial pressure ratio, and total intracavernous pressure measured." | 8.12 | Prolonged isoflurane anesthesia-induced acidosis decreases penile intracavernous pressure in rats. ( Ma, M; Qin, F; Wei, S; Wu, C; Yu, B; Yuan, J, 2022) |
| "To investigate the protective effects of metformin on the diabetic mice with cognitive impairment induced by the combination of streptozotocin (STZ) and isoflurane anesthesia." | 8.02 | Metformin improves cognitive impairment in diabetic mice induced by a combination of streptozotocin and isoflurane anesthesia. ( Li, P; Lv, Z; Zhang, J; Zhang, W; Zhao, L, 2021) |
| "We recently reported that isoflurane conditioning provided multifaceted protection against subarachnoid hemorrhage (SAH)-induced delayed cerebral ischemia (DCI), and this protection was through the upregulation of endothelial nitric oxide synthase (eNOS)." | 8.02 | Role of SIRT1 in Isoflurane Conditioning-Induced Neurovascular Protection against Delayed Cerebral Ischemia Secondary to Subarachnoid Hemorrhage. ( Athiraman, U; Giri, T; Jayaraman, K; Liu, M; Zipfel, GJ, 2021) |
| "Isoflurane has been studied in ischemia-reperfusion injury, while the regulatory mechanism by which isoflurane regulates microRNA(miR)-9-3p in hepatic ischemia/reperfusion injury (HIRI) via targeting fibronectin type III domain containing 3B (FNDC3B) remains seldom investigated." | 8.02 | Isoflurane upregulates microRNA-9-3p to protect rats from hepatic ischemia-reperfusion injury through inhibiting fibronectin type III domain containing 3B. ( Guo, L; Song, S; Wang, H; Wang, Y, 2021) |
| "It has been demonstrated that administration of exogenous ketone supplement ketone salt (KS) and ketone ester (KE) increased blood ketone level and delayed the onset of isoflurane-induced anesthesia in different rodent models, such as Wistar Albino Glaxo Rijswijk (WAG/Rij) rats." | 7.96 | Inhibition of adenosine A1 receptors abolished the nutritional ketosis-evoked delay in the onset of isoflurane-induced anesthesia in Wistar Albino Glaxo Rijswijk rats. ( Ari, C; Brunner, B; D'Agostino, DP; Kovács, Z, 2020) |
| " We investigated whether intracranial space-occupying lesions (ICSOLs) inducing intracranial hypertension increase isoflurane's effect on electroencephalographic (EEG) results." | 7.91 | Intracranial Space-occupying Lesion Inducing Intracranial Hypertension Increases the Encephalographic Effects of Isoflurane in a Swine Model. ( Kawashima, S; Kurita, T; Morita, K; Nakajima, Y, 2019) |
| " To investigate the intervention of exogenous adiponectin in the elderly rats with cognitive dysfunction induced by isoflurane through mitogen-activated protein kinase (MAPK) signaling pathway in hippocampus." | 7.91 | Adiponectin improves isoflurane-induced cognitive dysfunction in elderly rats via inhibiting p38-MAPK signal pathway in hippocampus. ( Chen, BN; Luo, YP; Wang, X; Zhang, FX; Zhang, JC; Zhang, WJ; Zhao, Q, 2019) |
| "Objective We compared the effects of sevoflurane and isoflurane on systemic inflammation, sepsis-associated encephalopathy, and memory impairment in a rat sepsis model of cecal ligation and puncture (CLP)-induced polymicrobial peritonitis." | 7.88 | Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis. ( Bagriacik, EU; Bedirli, A; Bedirli, N; Cavunt Bayraktar, A; Kavutçu, M; Ozkose, Z; Yilmaz, G, 2018) |
| "The effects of combined therapy with isoflurane and oxygen on lung injury and sepsis were determined in animal models of sepsis induced by cecal ligation and puncture (CLP) or intraperitoneal injection of lipopolysaccharide (LPS) or zymosan." | 7.85 | Sub-anesthesia Dose of Isoflurane in 60% Oxygen Reduces Inflammatory Responses in Experimental Sepsis Models. ( Dong, HL; Han, H; Hou, LC; Hou, ZX; Huang, Y; Pu, ZS; Shao, T; Sun, DD; Wang, XX; Xiong, LZ; Yang, WW; Zhang, EF; Zhang, ZX, 2017) |
| " Therefore, the intriguing ability of several anesthetics to readily inhibit GSK3β within the cortex and hippocampus led us to investigate the effects of brief isoflurane anesthesia on striatal GSK3β signaling in naïve rats and in a rat model of early-stage PD." | 7.85 | Brief isoflurane anesthesia regulates striatal AKT-GSK3β signaling and ameliorates motor deficits in a rat model of early-stage Parkinson's disease. ( Forsberg, MM; Jalkanen, AJ; Kohtala, S; Leikas, JV; Rantamäki, T; Theilmann, W, 2017) |
| " An indiscriminate use of isoflurane-based surgical anesthesia with or without nitrous oxide may act as an unconstrained, untraceable source of data variability, potentially causing false-positive or false-negative results." | 7.85 | Duration of isoflurane-based surgical anesthesia determines severity of brain injury and neurological deficits after a transient focal ischemia in young adult rats. ( Gaidhani, N; Schreihofer, D; Sun, F; Uteshev, VV, 2017) |
| "Our results demonstrate that the administration of inhaled isoflurane in spinal cord ischemia-reperfusion injury impairs the recovery of motor function." | 7.85 | Isoflurane Impairs Motor Function Recovery by Increasing Neuroapoptosis and Degeneration During Spinal Ischemia-Reperfusion Injury in Rats. ( Fang, SY; Lam, CF; Lee, JS; Roan, JN; Tsai, YC, 2017) |
| "Mitochondrial dysfunction has been linked to the earliest pathogenesis of isoflurane-induced cognitive impairments in developing or aging mammalian brain." | 7.83 | BDNF pathway is involved in the protective effects of SS-31 on isoflurane-induced cognitive deficits in aging mice. ( Hao, S; Ji, M; Li, H; Li, K; Sun, X; Wu, J; Yang, J; Zhang, M, 2016) |
| " Two common means of anesthesia before euthanasia and bronchoalveolar lavage in rats are intraperitoneal injection of pentobarbital and inhalation of isoflurane." | 7.83 | Effects of pentobarbital, isoflurane, or medetomidine-midazolam-butorphanol anesthesia on bronchoalveolar lavage fluid and blood chemistry in rats. ( Ajimi, S; Hashizume, N; Imatanaka, N; Kobayashi, T; Nakai, M; Oshima, Y; Tsubokura, Y, 2016) |
| " In developing a model, we compared the hemodynamic effects of isoflurane and α-chloralose in an acute swine model of PE because the choice of anesthesia will likely affect the cardiovascular responses of an animal to PE." | 7.81 | Comparison of isoflurane and α-chloralose in an anesthetized swine model of acute pulmonary embolism producing right ventricular dysfunction. ( Alves, NJ; Beam, DM; Kline, JA; Neto-Neves, EM; Stubblefield, WB; Tune, JD, 2015) |
| "Cerebral blood flow (CBF) and blood-brain barrier (BBB) permeability by arterial spin labeling (ASL)- and dynamic contrast enhanced (DCE)-magnetic resonance imaging (MRI), respectively were repeatedly measured under either halothane (N = 5) or isoflurane (N = 5) anesthesia in a rat stroke model of embolic occlusion of middle cerebral artery (MCA)." | 7.80 | Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke. ( Alarcon, W; Bezerra, FJ; Brown, M; Karki, K; Keenan, KA; Knight, RA; Nagaraja, TN, 2014) |
| "Since an ethical issue has been raised regarding the use of the well-known anesthetic agent chloral hydrate, owing to its mutagenic and carcinogenic effects in animals, attention of neuroscientists has turned to finding out an alternative agent able to meet not only potency, safety, and analgesic efficacy, but also reduced neuroprotective effect for stroke research." | 7.80 | Evidence for the use of isoflurane as a replacement for chloral hydrate anesthesia in experimental stroke: an ethical issue. ( Cédrick, L; Maud, P; Michèle, B; Olivier, P; Régis, B; Thavarak, O; Vincent, B, 2014) |
| "The volatile anesthetic isoflurane protects against renal ischemia and reperfusion injury by releasing renal tubular TGF-β1." | 7.79 | The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury. ( Brown, KM; D'Agati, VD; Ham, A; Kim, JY; Kim, M; Lee, HT, 2013) |
| "Compared to isoflurane and s-ketamine, xenon limited progressive adverse cardiac remodeling and contractile dysfunction 28 days after perioperative myocardial infarction." | 7.79 | Xenon and isoflurane reduce left ventricular remodeling after myocardial infarction in the rat. ( Becker, MM; Bleilevens, C; Funcke, S; Goetzenich, A; Hein, M; Roehl, AB; Rossaint, R; Steendijk, P, 2013) |
| "Male Sprague-Dawley (SD) rats were randomly divided into five groups: a control group, a hemorrhagic shock (HS) group, an intralipid (IL) group, an isoflurane (Iso) group, and an emulsified isoflurane (E-Iso) group." | 7.77 | Emulsified isoflurane preconditioning protects against liver and lung injury in rat model of hemorrhagic shock. ( Cheng, J; Du, G; Duan, Z; Li, Z; Lin, H; Liu, J; Luo, N; Zhang, L, 2011) |
| " The aim of this study was to investigate whether isoflurane preconditioning provides a protection against renal ischemic-reperfusion injury and whether hypoxia inducible factor 1 α (HIF-1 α) is responsible for the protection afforded by isoflurane in mice." | 7.77 | Pre-treatment with isoflurane ameliorates renal ischemic-reperfusion injury in mice. ( Cheng, J; Huang, H; Liu, J; Ma, D; Vizcaychipi, MP; Zhang, L; Zhao, H, 2011) |
| "24 h prior to intracerebral hemorrhage, C57BL/6J mice were preconditioned with a 4-h exposure to 1% isoflurane gas or room air." | 7.77 | Isoflurane preconditioning affords functional neuroprotection in a murine model of intracerebral hemorrhage. ( Appelboom, G; Connolly, ES; Ducruet, AF; Gigante, PR; Gorski, J; Haque, RM; Hwang, BY; Keesecker, SE; Kellner, CP; Yeh, ML, 2011) |
| "This study presents our findings on the extent of neuronal damage in the hippocampal CA1-4 subfields following global (forebrain) cerebral ischemia in rats when using different blood pressure levels (37 vs 45 mmHg) and bilateral carotid occlusion durations (8 vs 10 min) under isoflurane anesthesia." | 7.77 | The effect of blood pressure (37 vs 45 mmHg) and carotid occlusion duration (8 vs 10 min) on CA1-4 neuronal damage when using isoflurane in a global cerebral ischemia rat model. ( Campbell, K; Knuckey, NW; Li, LX; Meloni, BP; Zhao, S, 2011) |
| "Preclinical evidence in rodents has suggested that inert gases, such as xenon or nitrous oxide, may be promising neuroprotective agents for treating acute ischemic stroke." | 7.77 | Interactions between nitrous oxide and tissue plasminogen activator in a rat model of thromboembolic stroke. ( Abraini, JH; Colloc'h, N; Colomb, DG; David, HN; Haelewyn, B; Risso, JJ, 2011) |
| "St Thomas cardioplegia solution supplemented with emulsified isoflurane enhanced its cardioprotection in an isolated heart ischemia reperfusion injury model in rats." | 7.76 | Cardioprotection afforded by St Thomas solution is enhanced by emulsified isoflurane in an isolated heart ischemia reperfusion injury model in rats. ( Huang, H; Li, T; Liu, J; Liu, S; Yanfang, C; Zhang, W, 2010) |
| "The effects of isoflurane pretreatment on pulmonary proinflammatory cytokines and survival in severe endotoxin-induced acute lung injury (ALI) have not been studied systemically." | 7.75 | Isoflurane preconditioning ameliorates endotoxin-induced acute lung injury and mortality in rats. ( Jiang, H; Li, QF; Sun, Y; Xu, H; Zhu, YS, 2009) |
| " As hyperactive uncontrolled inflammation can lead to mortality and morbidity during early sepsis, we questioned whether the volatile anesthetic isoflurane could reduce mortality and protect against sepsis induced renal and hepatic dysfunction." | 7.74 | Isoflurane improves survival and protects against renal and hepatic injury in murine septic peritonitis. ( Emala, CW; Joo, JD; Kim, M; Lee, HT, 2007) |
| "Hemorrhagic shock decreased the isoflurane MAC from 2." | 7.74 | The influence of hemorrhagic shock on the minimum alveolar anesthetic concentration of isoflurane in a swine model. ( Katoh, T; Kurita, T; Morita, K; Sanjo, Y; Sato, S; Takata, K; Uraoka, M, 2007) |
| "To investigate the protective effect of pretreatment with Kupffer cell mediated emulsified isoflurane on ischemia/reperfusion injury in liver." | 7.74 | [Protection of liver against ischemia/reperfusion injury by Kupffer cell mediated emulsified isoflurane preconditioning: experiment with rats]. ( Li, Q; Lü, H; Ren, HM; Xu, LY; Yang, LQ; Yu, WF; Zhu, M, 2007) |
| "The current study was undertaken to investigate the effects of pretreatment with isoflurane and sevoflurane on the development of neurogenic pulmonary edema in an animal model." | 7.73 | Opposing effects of isoflurane and sevoflurane on neurogenic pulmonary edema development in an animal model. ( Feng, GG; Hirokawa, M; Ishikawa, K; Ishikawa, N; Kandatsu, N; Komatsu, T; Nan, YS; Nishiwaki, K; Shimada, Y; Yokochi, T, 2005) |
| "We compared the postischemic cerebral protective effects of sevoflurane and desflurane in rats with incomplete cerebral ischemia." | 7.73 | Effects of sevoflurane and desflurane in CA1 after incomplete cerebral ischemia in rats. ( Alici, HA; Cesur, M; Dogan, N; Erdem, AF; Erdogan, F; Kursad, H; Yuksek, MS, 2005) |
| "F 13640 is a newly discovered high-efficacy 5-HT(1A) receptor agonist that produces exceptional analgesia in animal models of tonic and chronic, nociceptive and neuropathic pains by novel molecular and neuroadaptive mechanisms." | 7.73 | The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain. ( Bardin, L; Colpaert, FC; Degryse, AD; Gomez de Segura, IA; Kiss, I, 2005) |
| "Although TIVA is less prone than isoflurane anaesthesia to primary cardiovascular depression leading to asphyxia, TIVA is associated with reduced effectiveness of CPR in which resuscitation because of asphyxic haemodynamic depression occurs." | 7.72 | Comparison of isoflurane and propofol-fentanyl anaesthesia in a swine model of asphyxia. ( Kazama, T; Kurita, T; Morita, K; Sato, S, 2003) |
| "More cerebral vasodilation at hypocapnia with high doses of desflurane than with sevoflurane or isoflurane indicates that desflurane might be less suitable for neuroanaesthesia than sevoflurane and isoflurane." | 7.72 | Desflurane results in higher cerebral blood flow than sevoflurane or isoflurane at hypocapnia in pigs. ( Akeson, J; Holmström, A; Rosén, I, 2004) |
| "Eight rabbits tracheotomized and vascularly cannulated under 3% isoflurane anesthesia were placed on a sling that allowed for free movement of the head and extremities." | 7.72 | A rabbit model for evaluation of surgical anesthesia and analgesia: characterization and validation with isoflurane anesthesia and fentanyl analgesia. ( Arita, H; Fukuda, K; Fukunaga, A; Hanaoka, K; Hayashida, M; Yamazaki, SY, 2004) |
| "In dogs, intraoperative cardiac tamponade caused comparable changes in RBF under the different anesthetic techniques except that autoregulation was effective in maintaining RBF within the central nervous system only under isoflurane anesthesia." | 7.72 | Isoflurane preserves central nervous system blood flow during intraoperative cardiac tamponade in dogs. ( Crystal, GJ; Metwally, AA; Salem, MR, 2004) |
| " In order to study the effects of anesthetic agents on the inducibility of TdP, arrhythmias were induced by programmed electrical stimulation (PES) before and after cumulative intravenous administration of quinidine under anesthesia with sodium pentobarbital, halothane, or isoflurane." | 7.71 | Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole. ( Imai, R; Tamura, T; Yamamoto, K; Yamamoto, M, 2001) |
| "In order to evaluate the effect of brain acidosis on neuronal functions as assessed by the in vivo studies, changes of cerebral blood flow (CBF), brain pH ([pH]o) and brain amino acid levels in the same brain region of the two different acidosis model rats were measured under isoflurane anesthesia." | 7.70 | [Acidosis and neuroprotection in two types of acidosis model rats under isoflurane anesthesia: evaluation of blood flow, pH and amino acid levels in the cortex]. ( Issiki, A; Kusagaya, H; Shimizu, A, 1998) |
| " Methohexital-anesthetized animals developed pulmonary dysfunction after 1 hr of bacteremia, whereas isoflurane-anesthetized animals developed pulmonary dysfunction after 3." | 7.68 | Pulmonary venodilation by isoflurane improves gas exchange during Escherichia coli bacteremia. ( Deusch, H; Fretschner, R; Guggenberger, H; Klöss, T; Schmid, HJ, 1993) |
| "Acute lung injury is one of major complications associated with sepsis, responsible for morbidity and mortality." | 5.72 | Isoflurane attenuates sepsis-associated lung injury. ( Kobayashi, Y; Koutsogiannaki, S; Ogawa, N; Okuno, T; Yuki, K, 2022) |
| " Our data show that isoflurane dosing typically used for general anesthesia (1%) or sedation (0." | 5.62 | Anesthetic and subanesthetic doses of isoflurane conditioning provides strong protection against delayed cerebral ischemia in a mouse model of subarachnoid hemorrhage. ( Athiraman, U; Jayaraman, K; Liu, M; Mehla, J; Yuan, J; Zipfel, GJ, 2021) |
| "The first step to treat aneurysmal subarachnoid hemorrhage (SAH) is aneurysmal obliteration under general anesthesia but not treat the SAH itself and the secondary effects." | 5.56 | Isoflurane versus sevoflurane for early brain injury and expression of sphingosine kinase 1 after experimental subarachnoid hemorrhage. ( Altay, BN; Altay, O; Calisir, V; Suzuki, H; Tang, J; Zhang, JH, 2020) |
| "Background Delayed cerebral ischemia remains a common and profound risk factor for poor outcome after subarachnoid hemorrhage (SAH)." | 5.56 | Role of Endothelial Nitric Oxide Synthase in Isoflurane Conditioning-Induced Neurovascular Protection in Subarachnoid Hemorrhage. ( Athiraman, U; Giri, T; Jayaraman, K; Liu, M; Yuan, J; Zipfel, GJ, 2020) |
| " Thus, the present study aimed to investigate the time-course and dose-response efficacy of a brief 4min isoflurane administration as a treatment for neurotoxicity induced by OP-CTA." | 5.46 | Brief isoflurane administration as a post-exposure treatment for organophosphate poisoning. ( Appu, AP; Arun, P; Braga, MF; Figueiredo, TH; Flagg, T; Krishnan, JKS; Moffett, JR; Namboodiri, AM; Puthillathu, N, 2017) |
| "Using a middle cerebral artery occlusion (MCAO) model, triphenyltetrazolium chloride staining was utilized to measure the infarct volume and brain edema and immunofluorescence staining was used to detect the MCAO-induced TLR4 expression and localization." | 5.42 | Protective role of isoflurane pretreatment in rats with focal cerebral ischemia and the underlying molecular mechanism. ( Chao, Y; Chen, L; Gao, C; Kuai, J; Lv, M; Ren, P; Sun, X; Wang, Q; Xiao, Z, 2015) |
| "Isoflurane treatment did not reduce brain edema compared with controls in any of the applied isoflurane concentrations." | 5.39 | Lower doses of isoflurane treatment has no beneficial effects in a rat model of intracerebral hemorrhage. ( Esposito, E; Lo, EH; Mandeville, ET, 2013) |
| "Morbid obesity affects the pharmacokinetics and pharmacodynamics of anesthetics, which may result in inappropriate dosing." | 5.38 | Determination of minimum alveolar concentration for isoflurane and sevoflurane in a rodent model of human metabolic syndrome. ( Britton, SL; Koch, LG; Lipinski, WJ; Lydic, R; Mashour, GA; Pal, D; Walton, ME, 2012) |
| "Temporary tinnitus is a common consequence of noise exposure, and may share important mechanisms with chronic tinnitus." | 5.38 | Isoflurane blocks temporary tinnitus. ( Norman, M; Tomscha, K; Wehr, M, 2012) |
| " Transient MCAO was induced during either isoflurane or ketamine/xylazine (ket/xyl) anesthesia with simultaneously measurement of cerebral blood flow (CBF) in 60 male Wistar rats (380-420 g)." | 5.17 | Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model. ( Bleilevens, C; Dang, J; Goetzenich, A; Hein, M; Kipp, M; Roehl, AB; Rossaint, R; Tolba, R; Zoremba, N, 2013) |
| " Here we compared sevoflurane and isoflurane with particular reference to their hemodynamic effects and ability to modify the effects of acute severe myocardial ischemia and reperfusion on ventricular arrhythmias and mortality in a porcine model of myocardial infarction." | 5.15 | Ventricular arrhythmias and mortality associated with isoflurane and sevoflurane in a porcine model of myocardial infarction. ( Ajenjo-Silverio, JM; Altónaga, JR; Cuellas-Ramón, C; de Prado, AP; Fernández-Vázquez, F; Gonzalo-Orden, JM; Orden, A; Regueiro-Purriños, M, 2011) |
| " The heart rhythm was monitored continuously and ventricular arrhythmias were treated with amiodarone and cardioversion." | 5.12 | Decreased mortality in a rat model of acute postinfarction heart failure. ( Lorentzon, M; Omerovic, E; Råmunddal, T, 2006) |
| "We were able to determine the effects of the duration of anesthesia using isoflurane on the transcriptomes in the brains of rats at 24 h after tMCAO." | 4.31 | Isoflurane Anesthesia's Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model. ( Denisova, AE; Dergunova, LV; Filippenkov, IB; Gubsky, LV; Limborska, SA; Shpetko, YY; Stavchansky, VV, 2023) |
| " Here, we used a mouse chronic pain model to test the hypothesis that early exposure to the general anesthetic (GA) Isoflurane causes cellular and molecular alterations in dorsal spinal cord (DSC) and dorsal root ganglion (DRG) that produces a predisposition to neuropathic pain via an upregulation of the mammalian target of the rapamycin (mTOR) signaling pathway." | 4.31 | Effects of Early Exposure to Isoflurane on Susceptibility to Chronic Pain Are Mediated by Increased Neural Activity Due to Actions of the Mammalian Target of the Rapamycin Pathway. ( Dong, X; Guan, Y; Li, F; Li, Q; Mathena, RP; Mintz, CD, 2023) |
| "Isoflurane-anesthetized rats developed systemic acidosis that worsens with time during intracavernous pressure measurement, which results in a significant decrease in the maximum intracavernous pressure value, intracavernous pressure/mean arterial pressure ratio, and total intracavernous pressure measured." | 4.12 | Prolonged isoflurane anesthesia-induced acidosis decreases penile intracavernous pressure in rats. ( Ma, M; Qin, F; Wei, S; Wu, C; Yu, B; Yuan, J, 2022) |
| "To investigate the protective effects of metformin on the diabetic mice with cognitive impairment induced by the combination of streptozotocin (STZ) and isoflurane anesthesia." | 4.02 | Metformin improves cognitive impairment in diabetic mice induced by a combination of streptozotocin and isoflurane anesthesia. ( Li, P; Lv, Z; Zhang, J; Zhang, W; Zhao, L, 2021) |
| "We recently reported that isoflurane conditioning provided multifaceted protection against subarachnoid hemorrhage (SAH)-induced delayed cerebral ischemia (DCI), and this protection was through the upregulation of endothelial nitric oxide synthase (eNOS)." | 4.02 | Role of SIRT1 in Isoflurane Conditioning-Induced Neurovascular Protection against Delayed Cerebral Ischemia Secondary to Subarachnoid Hemorrhage. ( Athiraman, U; Giri, T; Jayaraman, K; Liu, M; Zipfel, GJ, 2021) |
| "Isoflurane has been studied in ischemia-reperfusion injury, while the regulatory mechanism by which isoflurane regulates microRNA(miR)-9-3p in hepatic ischemia/reperfusion injury (HIRI) via targeting fibronectin type III domain containing 3B (FNDC3B) remains seldom investigated." | 4.02 | Isoflurane upregulates microRNA-9-3p to protect rats from hepatic ischemia-reperfusion injury through inhibiting fibronectin type III domain containing 3B. ( Guo, L; Song, S; Wang, H; Wang, Y, 2021) |
| "It has been demonstrated that administration of exogenous ketone supplement ketone salt (KS) and ketone ester (KE) increased blood ketone level and delayed the onset of isoflurane-induced anesthesia in different rodent models, such as Wistar Albino Glaxo Rijswijk (WAG/Rij) rats." | 3.96 | Inhibition of adenosine A1 receptors abolished the nutritional ketosis-evoked delay in the onset of isoflurane-induced anesthesia in Wistar Albino Glaxo Rijswijk rats. ( Ari, C; Brunner, B; D'Agostino, DP; Kovács, Z, 2020) |
| " We investigated whether intracranial space-occupying lesions (ICSOLs) inducing intracranial hypertension increase isoflurane's effect on electroencephalographic (EEG) results." | 3.91 | Intracranial Space-occupying Lesion Inducing Intracranial Hypertension Increases the Encephalographic Effects of Isoflurane in a Swine Model. ( Kawashima, S; Kurita, T; Morita, K; Nakajima, Y, 2019) |
| " Furthermore, the commonly used isoflurane anesthesia induces vasodilation and is thereby inherently a vascular challenge." | 3.91 | Longitudinal assessment of cerebral perfusion and vascular response to hypoventilation in a bigenic mouse model of Alzheimer's disease with amyloid and tau pathology. ( Borghgraef, P; Dresselaers, T; Govaerts, K; Himmelreich, U; Kremer, A; Lechat, B; Struys, T; Van Leuven, F, 2019) |
| "Isoflurane can, through inhibiting the p38 MAPK signaling pathway, effectively protect the cardiac function of rats from myocardial ischemia-reperfusion injury, reduce the area of myocardial infarction, alleviate the pathological damage in myocardial cells and reduce the oxidative stress response." | 3.91 | Effect of isoflurane on myocardial ischemia-reperfusion injury through the p38 MAPK signaling pathway. ( Chong, H; Peng, DD; Wang, G; Zheng, SQ; Zhou, Y; Zhu, F, 2019) |
| " To investigate the intervention of exogenous adiponectin in the elderly rats with cognitive dysfunction induced by isoflurane through mitogen-activated protein kinase (MAPK) signaling pathway in hippocampus." | 3.91 | Adiponectin improves isoflurane-induced cognitive dysfunction in elderly rats via inhibiting p38-MAPK signal pathway in hippocampus. ( Chen, BN; Luo, YP; Wang, X; Zhang, FX; Zhang, JC; Zhang, WJ; Zhao, Q, 2019) |
| " Isoflurane induced cognitive impairment and hippocampal inflammation in aged mice but not in young mice." | 3.88 | Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment. ( Cao, L; Chen, Y; Meng, S; Peng, S; Wang, Z; Zuo, Z, 2018) |
| "Objective We compared the effects of sevoflurane and isoflurane on systemic inflammation, sepsis-associated encephalopathy, and memory impairment in a rat sepsis model of cecal ligation and puncture (CLP)-induced polymicrobial peritonitis." | 3.88 | Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis. ( Bagriacik, EU; Bedirli, A; Bedirli, N; Cavunt Bayraktar, A; Kavutçu, M; Ozkose, Z; Yilmaz, G, 2018) |
| "The effects of combined therapy with isoflurane and oxygen on lung injury and sepsis were determined in animal models of sepsis induced by cecal ligation and puncture (CLP) or intraperitoneal injection of lipopolysaccharide (LPS) or zymosan." | 3.85 | Sub-anesthesia Dose of Isoflurane in 60% Oxygen Reduces Inflammatory Responses in Experimental Sepsis Models. ( Dong, HL; Han, H; Hou, LC; Hou, ZX; Huang, Y; Pu, ZS; Shao, T; Sun, DD; Wang, XX; Xiong, LZ; Yang, WW; Zhang, EF; Zhang, ZX, 2017) |
| " Therefore, the intriguing ability of several anesthetics to readily inhibit GSK3β within the cortex and hippocampus led us to investigate the effects of brief isoflurane anesthesia on striatal GSK3β signaling in naïve rats and in a rat model of early-stage PD." | 3.85 | Brief isoflurane anesthesia regulates striatal AKT-GSK3β signaling and ameliorates motor deficits in a rat model of early-stage Parkinson's disease. ( Forsberg, MM; Jalkanen, AJ; Kohtala, S; Leikas, JV; Rantamäki, T; Theilmann, W, 2017) |
| " An indiscriminate use of isoflurane-based surgical anesthesia with or without nitrous oxide may act as an unconstrained, untraceable source of data variability, potentially causing false-positive or false-negative results." | 3.85 | Duration of isoflurane-based surgical anesthesia determines severity of brain injury and neurological deficits after a transient focal ischemia in young adult rats. ( Gaidhani, N; Schreihofer, D; Sun, F; Uteshev, VV, 2017) |
| "Our results demonstrate that the administration of inhaled isoflurane in spinal cord ischemia-reperfusion injury impairs the recovery of motor function." | 3.85 | Isoflurane Impairs Motor Function Recovery by Increasing Neuroapoptosis and Degeneration During Spinal Ischemia-Reperfusion Injury in Rats. ( Fang, SY; Lam, CF; Lee, JS; Roan, JN; Tsai, YC, 2017) |
| " In the present study, we utilized our recently developed photothrombotic model of focal cerebral ischemia in conscious and freely moving rats, and investigated transient hemodynamic changes with or without isoflurane administration." | 3.85 | Hemodynamic effects of intraoperative anesthetics administration in photothrombotic stroke model: a study using laser speckle imaging. ( Bo, B; Li, H; Li, Y; Lu, H; Lu, X; Tong, S; Yuan, L, 2017) |
| "Mitochondrial dysfunction has been linked to the earliest pathogenesis of isoflurane-induced cognitive impairments in developing or aging mammalian brain." | 3.83 | BDNF pathway is involved in the protective effects of SS-31 on isoflurane-induced cognitive deficits in aging mice. ( Hao, S; Ji, M; Li, H; Li, K; Sun, X; Wu, J; Yang, J; Zhang, M, 2016) |
| " Two common means of anesthesia before euthanasia and bronchoalveolar lavage in rats are intraperitoneal injection of pentobarbital and inhalation of isoflurane." | 3.83 | Effects of pentobarbital, isoflurane, or medetomidine-midazolam-butorphanol anesthesia on bronchoalveolar lavage fluid and blood chemistry in rats. ( Ajimi, S; Hashizume, N; Imatanaka, N; Kobayashi, T; Nakai, M; Oshima, Y; Tsubokura, Y, 2016) |
| " In developing a model, we compared the hemodynamic effects of isoflurane and α-chloralose in an acute swine model of PE because the choice of anesthesia will likely affect the cardiovascular responses of an animal to PE." | 3.81 | Comparison of isoflurane and α-chloralose in an anesthetized swine model of acute pulmonary embolism producing right ventricular dysfunction. ( Alves, NJ; Beam, DM; Kline, JA; Neto-Neves, EM; Stubblefield, WB; Tune, JD, 2015) |
| " The effects of isoflurane, propofol, apnea, and hypotension on lower extremity MEPs were studied." | 3.81 | Methodology of motor evoked potentials in a rabbit model. ( Bombien, R; Goodwin, E; Haji, F; Juan, V; Khoynezhad, A; Lapchak, PA; Rastegar, M; Waterford, SD, 2015) |
| "Cerebral blood flow (CBF) and blood-brain barrier (BBB) permeability by arterial spin labeling (ASL)- and dynamic contrast enhanced (DCE)-magnetic resonance imaging (MRI), respectively were repeatedly measured under either halothane (N = 5) or isoflurane (N = 5) anesthesia in a rat stroke model of embolic occlusion of middle cerebral artery (MCA)." | 3.80 | Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke. ( Alarcon, W; Bezerra, FJ; Brown, M; Karki, K; Keenan, KA; Knight, RA; Nagaraja, TN, 2014) |
| "Since an ethical issue has been raised regarding the use of the well-known anesthetic agent chloral hydrate, owing to its mutagenic and carcinogenic effects in animals, attention of neuroscientists has turned to finding out an alternative agent able to meet not only potency, safety, and analgesic efficacy, but also reduced neuroprotective effect for stroke research." | 3.80 | Evidence for the use of isoflurane as a replacement for chloral hydrate anesthesia in experimental stroke: an ethical issue. ( Cédrick, L; Maud, P; Michèle, B; Olivier, P; Régis, B; Thavarak, O; Vincent, B, 2014) |
| "The volatile anesthetic isoflurane protects against renal ischemia and reperfusion injury by releasing renal tubular TGF-β1." | 3.79 | The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury. ( Brown, KM; D'Agati, VD; Ham, A; Kim, JY; Kim, M; Lee, HT, 2013) |
| "During CPB, isoflurane, in contrast to propofol, significantly contributes to a general increase in fluid shifts from the intravascular to the interstitial space with edema formation and a possible negative impact on postoperative organ function." | 3.79 | Isoflurane in contrast to propofol promotes fluid extravasation during cardiopulmonary bypass in pigs. ( Brekke, HK; Hammersborg, SM; Haugen, O; Husby, P; Kvalheim, VL; Lundemoen, S; Mongstad, A, 2013) |
| "Mice (N = 12 per treatment group) were exposed to anesthetic concentrations of desflurane, isoflurane, and sevoflurane either during induction of sepsis or when the mice showed pronounced symptoms of inflammation." | 3.79 | Volatile anesthetics improve survival after cecal ligation and puncture. ( Beck-Schimmer, B; Castellon, M; Hasler, M; Herrmann, IK; Hu, G; Minshall, RD; Schwartz, DE; Urner, M, 2013) |
| "Isoflurane (ISO) has been shown to attenuate acute lung injury (ALI)." | 3.79 | Isoflurane post-treatment improves pulmonary vascular permeability via upregulation of heme oxygenase-1. ( Dong, X; Hu, R; Jiang, H; Li, Q; Sun, Y, 2013) |
| "Compared to isoflurane and s-ketamine, xenon limited progressive adverse cardiac remodeling and contractile dysfunction 28 days after perioperative myocardial infarction." | 3.79 | Xenon and isoflurane reduce left ventricular remodeling after myocardial infarction in the rat. ( Becker, MM; Bleilevens, C; Funcke, S; Goetzenich, A; Hein, M; Roehl, AB; Rossaint, R; Steendijk, P, 2013) |
| " In the present study, we describe a simple model of mouse forebrain ischemia where the bilateral common carotid artery occlusion (BCCO) is combined with isoflurane-induced hypotension." | 3.78 | Simple model of forebrain ischemia in mouse. ( Berger, S; Kristian, T; Onken, M, 2012) |
| "This study aimed to evaluate the differential protective effects of isoflurane or sevoflurane on lung inflammation in a rat model of cecal ligation and puncture (CLP) induced sepsis." | 3.78 | Volatile anesthetic preconditioning attenuated sepsis induced lung inflammation. ( Akkaya, T; Alper, M; Bedirli, A; Bedirli, N; Demirtas, CY; Pasaoglu, H; Salman, B, 2012) |
| "Dexmedetomidine prevented surgical stress and pain-related tachycardia and hypertension, and it attenuated the reduction of the microcirculatory blood flow intensity in intestinal mucosa (1100 ± 185 perfusion units [PU] vs 800 ± 105 PU, P = 0." | 3.78 | Dexmedetomidine prevents alterations of intestinal microcirculation that are induced by surgical stress and pain in a novel rat model. ( Chan, WS; Fan, SZ; Ko, WJ; Lin, TY; Sun, WZ; Tsai, JC; Yeh, YC, 2012) |
| "5h) revealed anesthesia associated IFNγ-expression and lymphocyte activation which were not observed when animals were treated with ketamine/xylazine (p<0." | 3.78 | Inflammatory immune responses in a reproducible mouse brain death model. ( Floerchinger, B; Ge, X; Jurisch, A; Lee, YL; Schmid, C; Timsit, MO; Tullius, SG; Yuan, X, 2012) |
| "The purpose of this investigation was to examine the effect of caffeic acid phenethyl ester (CAPE) in renal ischemia/reperfusion injury in rats anesthetized with isoflurane (iso)." | 3.78 | Caffeic acid phenethyl ester effects in the kidney during ischemia and reperfusion in rats anesthetized with isoflurane. ( Carvalho, LR; Castiglia, YM; Correa, RR; de Oliveira, CC; de Souza, AV; Roso, NC; Scatena, LM; Vianna, PT, 2012) |
| "Adenosine and high-concentration isoflurane are commonly used to induce hyperemia for assessment of coronary flow reserve (CFR) in mice, but high-concentration isoflurane may exacerbate cardiac dysfunction, leading to impaired CFR." | 3.78 | Comparison between adenosine and isoflurane for assessing the coronary flow reserve in mouse models of left ventricular pressure and volume overload. ( Ge, J; Wu, J; You, J; Zou, Y, 2012) |
| "Isoflurane anesthesia reduced the recovery time and incidence of hypoglycemia and increased the survival rate in the early hours, providing a therapeutic window that is suitable for experimental studies." | 3.78 | The effects of anesthetic regimen in 90% hepatectomy in rats. ( Backes, AN; Cruz, CU; Kieling, CO; Matte, Uda S; Maurer, RL; Osvaldt, AB; Silveira, TR, 2012) |
| "Many in vitro findings suggest that isoflurane exposure might accelerate the process of Alzheimer Disease (AD); however, no behavioral evidence exists to support this theory." | 3.78 | Isoflurane exposure during mid-adulthood attenuates age-related spatial memory impairment in APP/PS1 transgenic mice. ( Chen, J; Chen, X; Su, D; Wang, B; Wang, X; Xu, H; Zhao, Y, 2012) |
| "Male Sprague-Dawley (SD) rats were randomly divided into five groups: a control group, a hemorrhagic shock (HS) group, an intralipid (IL) group, an isoflurane (Iso) group, and an emulsified isoflurane (E-Iso) group." | 3.77 | Emulsified isoflurane preconditioning protects against liver and lung injury in rat model of hemorrhagic shock. ( Cheng, J; Du, G; Duan, Z; Li, Z; Lin, H; Liu, J; Luo, N; Zhang, L, 2011) |
| " The aim of this study was to investigate whether isoflurane preconditioning provides a protection against renal ischemic-reperfusion injury and whether hypoxia inducible factor 1 α (HIF-1 α) is responsible for the protection afforded by isoflurane in mice." | 3.77 | Pre-treatment with isoflurane ameliorates renal ischemic-reperfusion injury in mice. ( Cheng, J; Huang, H; Liu, J; Ma, D; Vizcaychipi, MP; Zhang, L; Zhao, H, 2011) |
| "24 h prior to intracerebral hemorrhage, C57BL/6J mice were preconditioned with a 4-h exposure to 1% isoflurane gas or room air." | 3.77 | Isoflurane preconditioning affords functional neuroprotection in a murine model of intracerebral hemorrhage. ( Appelboom, G; Connolly, ES; Ducruet, AF; Gigante, PR; Gorski, J; Haque, RM; Hwang, BY; Keesecker, SE; Kellner, CP; Yeh, ML, 2011) |
| "This study presents our findings on the extent of neuronal damage in the hippocampal CA1-4 subfields following global (forebrain) cerebral ischemia in rats when using different blood pressure levels (37 vs 45 mmHg) and bilateral carotid occlusion durations (8 vs 10 min) under isoflurane anesthesia." | 3.77 | The effect of blood pressure (37 vs 45 mmHg) and carotid occlusion duration (8 vs 10 min) on CA1-4 neuronal damage when using isoflurane in a global cerebral ischemia rat model. ( Campbell, K; Knuckey, NW; Li, LX; Meloni, BP; Zhao, S, 2011) |
| "Preclinical evidence in rodents has suggested that inert gases, such as xenon or nitrous oxide, may be promising neuroprotective agents for treating acute ischemic stroke." | 3.77 | Interactions between nitrous oxide and tissue plasminogen activator in a rat model of thromboembolic stroke. ( Abraini, JH; Colloc'h, N; Colomb, DG; David, HN; Haelewyn, B; Risso, JJ, 2011) |
| "0 MAC halothane, isoflurane, and sevoflurane on phrenic nerve activity in euoxia (baseline) and during acute normocapnic hypoxia (inspired oxygen fraction 0." | 3.76 | The acute hypoxic ventilatory response under halothane, isoflurane, and sevoflurane anaesthesia in rats. ( Carev, M; Dogas, Z; Jeroncic, A; Karanovic, N; Karanovic, S; Pecotic, R; Ujevic, A; Valic, M, 2010) |
| "St Thomas cardioplegia solution supplemented with emulsified isoflurane enhanced its cardioprotection in an isolated heart ischemia reperfusion injury model in rats." | 3.76 | Cardioprotection afforded by St Thomas solution is enhanced by emulsified isoflurane in an isolated heart ischemia reperfusion injury model in rats. ( Huang, H; Li, T; Liu, J; Liu, S; Yanfang, C; Zhang, W, 2010) |
| "In this study, we sought to clarify the role of inhibiting ubiquitin-conjugated protein aggregation in the formation of a neuroprotective effect after isoflurane preconditioning using a transient global cerebral ischemia-reperfusion injury mouse model." | 3.76 | Isoflurane preconditioning induces neuroprotection by attenuating ubiquitin-conjugated protein aggregation in a mouse model of transient global cerebral ischemia. ( Dong, HL; Ma, R; Tong, L; Xiong, L; Yuan, LB; Zhang, HP; Zhao, RN, 2010) |
| "We conclude that no difference could be detected between choosing equipotent doses of halothane, sevoflurane, or isoflurane in relation to renal variables in dogs submitted to pressure-adjusted hemorrhagic shock and resuscitation." | 3.75 | Does the choice of the halogenated anesthetic influence renal function during hemorrhagic shock and resuscitation? ( Braz, JR; Braz, LG; Castiglia, YM; Módolo, NS; Roberto, WM; Silva, AE; Vane, LA; Vianna, PT, 2009) |
| "The effects of isoflurane pretreatment on pulmonary proinflammatory cytokines and survival in severe endotoxin-induced acute lung injury (ALI) have not been studied systemically." | 3.75 | Isoflurane preconditioning ameliorates endotoxin-induced acute lung injury and mortality in rats. ( Jiang, H; Li, QF; Sun, Y; Xu, H; Zhu, YS, 2009) |
| " As hyperactive uncontrolled inflammation can lead to mortality and morbidity during early sepsis, we questioned whether the volatile anesthetic isoflurane could reduce mortality and protect against sepsis induced renal and hepatic dysfunction." | 3.74 | Isoflurane improves survival and protects against renal and hepatic injury in murine septic peritonitis. ( Emala, CW; Joo, JD; Kim, M; Lee, HT, 2007) |
| " After having established the mouse model of analgesia by intraperitoneal or subcutaneous injections of appropriate doses of emulsified enflurane, isoflurane or sevoflurane, we injected different doses of AMPA intrathecally and observed effects on the pain threshold using the hot-plate and acetic acid-induced writhing tests." | 3.74 | Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics. ( Dai, TJ; Hang, LH; Shao, DH; Yang, YH; Zeng, YM, 2007) |
| " The authors compared CBF imaging using flow sensitive alternating inversion recovery (FAIR)-MRI and (14)C-Iodoantipyrine (IAP)-autoradiography in a mouse model of acute stroke." | 3.74 | A flow sensitive alternating inversion recovery (FAIR)-MRI protocol to measure hemispheric cerebral blood flow in a mouse stroke model. ( Dirnagl, U; Endres, M; Gertz, K; Leithner, C; Lindauer, U; Prass, K; Priller, J; Royl, G; Schröck, H; Steinbrink, J; Villringer, A, 2008) |
| "Hemorrhagic shock decreased the isoflurane MAC from 2." | 3.74 | The influence of hemorrhagic shock on the minimum alveolar anesthetic concentration of isoflurane in a swine model. ( Katoh, T; Kurita, T; Morita, K; Sanjo, Y; Sato, S; Takata, K; Uraoka, M, 2007) |
| "To investigate the protective effect of pretreatment with Kupffer cell mediated emulsified isoflurane on ischemia/reperfusion injury in liver." | 3.74 | [Protection of liver against ischemia/reperfusion injury by Kupffer cell mediated emulsified isoflurane preconditioning: experiment with rats]. ( Li, Q; Lü, H; Ren, HM; Xu, LY; Yang, LQ; Yu, WF; Zhu, M, 2007) |
| "Using an IPC of 2 5-minute MCAO episodes, the reduction in infarct volume from the test MCAO was maximal with a 72-hour delay in striatum (70%) and cerebral cortex (64%) when halothane was used for surgical anesthesia." | 3.74 | Delayed tolerance with repetitive transient focal ischemic preconditioning in the mouse. ( Huang, J; Klaus, JA; Koehler, RC; Yang, ZJ; Zhang, J, 2008) |
| "Repeated exposure to isoflurane suppressed myocardial myoglobin release caused by both ischemia and reperfusion injury." | 3.74 | Isoflurane attenuates myoglobin release during ischemic and/or reperfusion periods. ( Akiyama, T; Kitagawa, H; Mori, H; Nosaka, S; Yamazaki, T, 2008) |
| "Farm-raised pigs were anesthetized with isoflurane, kept normocapnic and normothermic, and subjected to conditions of euvolemic or hypovolemic hypotension (mean arterial pressure 50-55 mm Hg), anemia (hematocrit 17%), venous congestion, and combinations thereof." | 3.74 | Effects of anemia and hypotension on porcine optic nerve blood flow and oxygen delivery. ( An, D; Deem, S; Glenny, RW; Lam, A; Lee, LA; Moulding, J; Townsend, I; Treggiari, MM, 2008) |
| " Flow maps of normal rat brains and those containing a 9L gliosarcoma orthotopic tumor model conditions were acquired with and without carbogen." | 3.73 | Continuous arterial spin labeling using a train of adiabatic inversion pulses. ( Chenevert, TL; Hall, DE; Moffat, BA; Rehemtulla, A; Ross, BD, 2005) |
| "The current study was undertaken to investigate the effects of pretreatment with isoflurane and sevoflurane on the development of neurogenic pulmonary edema in an animal model." | 3.73 | Opposing effects of isoflurane and sevoflurane on neurogenic pulmonary edema development in an animal model. ( Feng, GG; Hirokawa, M; Ishikawa, K; Ishikawa, N; Kandatsu, N; Komatsu, T; Nan, YS; Nishiwaki, K; Shimada, Y; Yokochi, T, 2005) |
| "Intra-arterial metabolic radiotherapy (using lipiodol labelled with iodine-131 or rhenium-188) is a therapeutic approach that can be used for the treatment of hepatocellular carcinomas (HCC)." | 3.73 | Description and technical pitfalls of a hepatoma model and of intra-arterial injection of radiolabelled lipiodol in the rat. ( Benoit, JP; Bourguet, P; Denizot, B; Garin, E; Herry, JY; Laurent, JF; Lejeune, JJ; Lepareur, N; Mesba, H; Moreau, M; Noiret, N; Roux, J, 2005) |
| "We compared the postischemic cerebral protective effects of sevoflurane and desflurane in rats with incomplete cerebral ischemia." | 3.73 | Effects of sevoflurane and desflurane in CA1 after incomplete cerebral ischemia in rats. ( Alici, HA; Cesur, M; Dogan, N; Erdem, AF; Erdogan, F; Kursad, H; Yuksek, MS, 2005) |
| "F 13640 is a newly discovered high-efficacy 5-HT(1A) receptor agonist that produces exceptional analgesia in animal models of tonic and chronic, nociceptive and neuropathic pains by novel molecular and neuroadaptive mechanisms." | 3.73 | The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain. ( Bardin, L; Colpaert, FC; Degryse, AD; Gomez de Segura, IA; Kiss, I, 2005) |
| "To compare adenosine-, isoflurane-, or desflurane-induced hypotension with and without left anterior descending (LAD) coronary artery constriction for the effects on myocardial tissue oxygen pressure (PmO(2)) in dogs." | 3.72 | Comparison of adenosine, isoflurane, and desflurane on myocardial tissue oxygen pressure during coronary artery constriction in dogs. ( Albrecht, RF; Hoffman, WE; Jonjev, ZS, 2003) |
| "Although TIVA is less prone than isoflurane anaesthesia to primary cardiovascular depression leading to asphyxia, TIVA is associated with reduced effectiveness of CPR in which resuscitation because of asphyxic haemodynamic depression occurs." | 3.72 | Comparison of isoflurane and propofol-fentanyl anaesthesia in a swine model of asphyxia. ( Kazama, T; Kurita, T; Morita, K; Sato, S, 2003) |
| "More cerebral vasodilation at hypocapnia with high doses of desflurane than with sevoflurane or isoflurane indicates that desflurane might be less suitable for neuroanaesthesia than sevoflurane and isoflurane." | 3.72 | Desflurane results in higher cerebral blood flow than sevoflurane or isoflurane at hypocapnia in pigs. ( Akeson, J; Holmström, A; Rosén, I, 2004) |
| "Isoflurane applied before myocardial ischemia has a beneficial preconditioning effect which involves generation of reactive oxygen species (ROS); ROS, however, have been implicated in critical cytosolic calcium ([Ca2+]i) overload during ischemia." | 3.72 | Isoflurane applied during ischemia enhances intracellular calcium accumulation in ventricular myocytes in part by reactive oxygen species. ( Breukelmann, D; Dworschak, M; Hannon, JD, 2004) |
| "Eight rabbits tracheotomized and vascularly cannulated under 3% isoflurane anesthesia were placed on a sling that allowed for free movement of the head and extremities." | 3.72 | A rabbit model for evaluation of surgical anesthesia and analgesia: characterization and validation with isoflurane anesthesia and fentanyl analgesia. ( Arita, H; Fukuda, K; Fukunaga, A; Hanaoka, K; Hayashida, M; Yamazaki, SY, 2004) |
| "In dogs, intraoperative cardiac tamponade caused comparable changes in RBF under the different anesthetic techniques except that autoregulation was effective in maintaining RBF within the central nervous system only under isoflurane anesthesia." | 3.72 | Isoflurane preserves central nervous system blood flow during intraoperative cardiac tamponade in dogs. ( Crystal, GJ; Metwally, AA; Salem, MR, 2004) |
| " In order to study the effects of anesthetic agents on the inducibility of TdP, arrhythmias were induced by programmed electrical stimulation (PES) before and after cumulative intravenous administration of quinidine under anesthesia with sodium pentobarbital, halothane, or isoflurane." | 3.71 | Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole. ( Imai, R; Tamura, T; Yamamoto, K; Yamamoto, M, 2001) |
| "In order to evaluate the effect of brain acidosis on neuronal functions as assessed by the in vivo studies, changes of cerebral blood flow (CBF), brain pH ([pH]o) and brain amino acid levels in the same brain region of the two different acidosis model rats were measured under isoflurane anesthesia." | 3.70 | [Acidosis and neuroprotection in two types of acidosis model rats under isoflurane anesthesia: evaluation of blood flow, pH and amino acid levels in the cortex]. ( Issiki, A; Kusagaya, H; Shimizu, A, 1998) |
| "For the evaluation of the hemodynamic interaction between the natural heart and an assist device, a reversible pharmacological model based on the channel blocker Verapamil under hyperkalemia, was developed for deterioration of left ventricular function." | 3.69 | Pharmacologically induced heart failure for the evaluation of circulatory assistance. ( Losert, U; Roschal, K; Schima, H; Schmidt, C; Schwendenwein, I; Wieselthaler, G; Wolner, E, 1996) |
| "Isoflurane and halothane produce favorable alterations in the determinants of left ventricular afterload before, but not after, the production of experimental left ventricular dysfunction by sustained, rapid cardiac pacing in chronically instrumented dogs." | 3.69 | The effects of isoflurane and halothane on left ventricular afterload in dogs with dilated cardiomyopathy. ( Hettrick, DA; Kersten, JR; Lowe, D; Pagel, PS; Warltier, DC, 1997) |
| " Methohexital-anesthetized animals developed pulmonary dysfunction after 1 hr of bacteremia, whereas isoflurane-anesthetized animals developed pulmonary dysfunction after 3." | 3.68 | Pulmonary venodilation by isoflurane improves gas exchange during Escherichia coli bacteremia. ( Deusch, H; Fretschner, R; Guggenberger, H; Klöss, T; Schmid, HJ, 1993) |
| "Sevoflurane was not associated with increases in heart rate in adult patients and volunteers, whereas higher MACs of isoflurane and desflurane and rapid increases in the inspired concentrations of these two anesthetics have been associated with tachycardia." | 2.39 | Cardiovascular responses to sevoflurane: a review. ( Ebert, TJ; Harkin, CP; Muzi, M, 1995) |
| "Sleep disorders, including sleep fragmentation, are reported to aggravate memory impairment in neurocognitive-related diseases such as Alzheimer's disease (AD)." | 1.91 | A modified mouse model of perioperative neurocognitive disorders exacerbated by sleep fragmentation. ( Cong, P; Huang, X; Li, M; Tian, L; Wu, H; Wu, T; Xiong, L; Zhang, H; Zhang, Q, 2023) |
| "Acute lung injury is one of major complications associated with sepsis, responsible for morbidity and mortality." | 1.72 | Isoflurane attenuates sepsis-associated lung injury. ( Kobayashi, Y; Koutsogiannaki, S; Ogawa, N; Okuno, T; Yuki, K, 2022) |
| " Our data show that isoflurane dosing typically used for general anesthesia (1%) or sedation (0." | 1.62 | Anesthetic and subanesthetic doses of isoflurane conditioning provides strong protection against delayed cerebral ischemia in a mouse model of subarachnoid hemorrhage. ( Athiraman, U; Jayaraman, K; Liu, M; Mehla, J; Yuan, J; Zipfel, GJ, 2021) |
| "Isoflurane is a commonly used inhalational anesthetic that can induce neurotoxicity, while Dexmedetomidine (Dex) has significant neuroprotective effects." | 1.56 | Dexmedetomidine pretreatment attenuates isoflurane-induced neurotoxicity via inhibiting the TLR2/NF-κB signaling pathway in neonatal rats. ( Liu, H; Pang, X; Zhang, P; Zhao, J; Zhou, Y, 2020) |
| "The first step to treat aneurysmal subarachnoid hemorrhage (SAH) is aneurysmal obliteration under general anesthesia but not treat the SAH itself and the secondary effects." | 1.56 | Isoflurane versus sevoflurane for early brain injury and expression of sphingosine kinase 1 after experimental subarachnoid hemorrhage. ( Altay, BN; Altay, O; Calisir, V; Suzuki, H; Tang, J; Zhang, JH, 2020) |
| " Isoflurane dosing is known to reliably produce rapid EEG burst-suppression (4% induction, 2% maintenance; 15 min)." | 1.56 | Lack of antidepressant effects of burst-suppressing isoflurane anesthesia in adult male Wistar outbred rats subjected to chronic mild stress. ( Hampel, P; Löscher, W; Rantamäki, T; Rosenholm, M; Theilmann, W, 2020) |
| "Isoflurane is a widely used anesthetic agent, which is associated with the development of POCD; however, the precise mechanisms remain unclear." | 1.56 | Effects of PYRIN-containing Apaf1-like protein 1 on isoflurane-induced postoperative cognitive dysfunction in aged rats. ( Fan, X; Li, F; Qiu, J; Zhang, X; Zhang, Y, 2020) |
| "Background Delayed cerebral ischemia remains a common and profound risk factor for poor outcome after subarachnoid hemorrhage (SAH)." | 1.56 | Role of Endothelial Nitric Oxide Synthase in Isoflurane Conditioning-Induced Neurovascular Protection in Subarachnoid Hemorrhage. ( Athiraman, U; Giri, T; Jayaraman, K; Liu, M; Yuan, J; Zipfel, GJ, 2020) |
| "We find that the seizure focus elicits a rapid alteration in triggering, initiation, and propagation of burst suppression events." | 1.51 | Burst suppression uncovers rapid widespread alterations in network excitability caused by an acute seizure focus. ( Baird-Daniel, E; Daniel, A; Liou, JY; Ma, H; Schevon, CA; Schwartz, TH; Zhao, M, 2019) |
| "Mechanical allodynia induced by plantar incision peaked at 1 hr and lasted for 3 days after incision." | 1.51 | Propofol attenuates postoperative hyperalgesia via regulating spinal GluN2B-p38MAPK/EPAC1 pathway in an animal model of postoperative pain. ( Cheung, CW; Gu, P; Li, Q; Qiu, Q; Sun, L; Wang, XM; Wong, SS, 2019) |
| "Routine general anesthesia is considered to be safe in healthy individuals." | 1.51 | Relevance of experimental paradigms of anesthesia induced neurotoxicity in the mouse. ( Bornstein, R; Ford, JM; Freed, A; Howard, CRA; Johnson, SC; Li, L; Morgan, PG; Pan, A; Sedensky, MM; Stokes, JC; Sun, GX; Witkowski, M, 2019) |
| "Isoflurane (0." | 1.48 | The Effect of Mitochondrial Complex I-Linked Respiration by Isoflurane Is Independent of Mitochondrial Nitric Oxide Production. ( An, J; Deng, Y; Li, H; Qiao, S; Wang, C; Xu, F, 2018) |
| " Thus, the present study aimed to investigate the time-course and dose-response efficacy of a brief 4min isoflurane administration as a treatment for neurotoxicity induced by OP-CTA." | 1.46 | Brief isoflurane administration as a post-exposure treatment for organophosphate poisoning. ( Appu, AP; Arun, P; Braga, MF; Figueiredo, TH; Flagg, T; Krishnan, JKS; Moffett, JR; Namboodiri, AM; Puthillathu, N, 2017) |
| "Because cerebral infarct develops within 24 h after the onset of ischemia, and several therapeutic agents have been shown to reduce the infarct volume when administered at 6 h post-ischemia, we hypothesized that attenuating BBB disruption at its peak (6 h post-ischemia) can also decrease the infarct volume measured at 24 h." | 1.46 | Anesthesia-Induced Hypothermia Attenuates Early-Phase Blood-Brain Barrier Disruption but Not Infarct Volume following Cerebral Ischemia. ( Chen, KB; Lai, TW; Lee, YD; Liao, KH; Liu, YC; Pan, YL; Poon, KS; Wang, HL, 2017) |
| "Treating isoflurane-exposed rats with ciproxifan significantly improved the memory performance, as evidenced by an increased discrimination ratio in objects recognition and prolonged retention time in passive avoidance test." | 1.46 | Histamine H3 Receptor Antagonist Prevents Memory Deficits and Synaptic Plasticity Disruption Following Isoflurane Exposure. ( Liu, M; Liu, ZG; Luo, T; Qin, J; Wang, Y, 2017) |
| "Desflurane failed to inhibit inflammatory responses and ROS production in lung tissue and developed no antioxidant potential." | 1.43 | Inhaled Anesthetics Exert Different Protective Properties in a Mouse Model of Ventilator-Induced Lung Injury. ( Buerkle, H; Engelstaedter, H; Faller, S; Gyllenram, V; Hoetzel, A; Spassov, S; Strosing, KM, 2016) |
| "Isoflurane exposure may cause potential neurotoxicity, which is tolerated to some extent in Zn-adequate APP/PS1 mice." | 1.43 | Isoflurane anesthesia exacerbates learning and memory impairment in zinc-deficient APP/PS1 transgenic mice. ( Cui, W; Feng, C; Liu, Y; Ma, Y; Piao, M; Yuan, Y; Zheng, F, 2016) |
| "Isoflurane was either administered during (kainate) or after (paraoxon) induction of SE." | 1.43 | Isoflurane prevents acquired epilepsy in rat models of temporal lobe epilepsy. ( Bankstahl, JP; Bankstahl, M; Bar-Klein, G; Bascuñana, P; Brandt, C; Dalipaj, H; Friedman, A; Klee, R; Löscher, W; Töllner, K, 2016) |
| "Using a middle cerebral artery occlusion (MCAO) model, triphenyltetrazolium chloride staining was utilized to measure the infarct volume and brain edema and immunofluorescence staining was used to detect the MCAO-induced TLR4 expression and localization." | 1.42 | Protective role of isoflurane pretreatment in rats with focal cerebral ischemia and the underlying molecular mechanism. ( Chao, Y; Chen, L; Gao, C; Kuai, J; Lv, M; Ren, P; Sun, X; Wang, Q; Xiao, Z, 2015) |
| "Increasingly more aged people with Alzheimer's disease (AD) must undergo surgery with general anesthesia for various reasons." | 1.40 | Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice. ( Deng, Y; He, Z; Lu, B; Qi, B; Su, D; Tian, J; Wang, X; Xu, H; Zheng, B, 2014) |
| "Susceptibility to motion sickness is a predictor of postoperative nausea and vomiting, and studies in humans suggest that genetic factors determine sensitivity to motion sickness." | 1.40 | Musk shrews selectively bred for motion sickness display increased anesthesia-induced vomiting. ( Horn, CC; Meyers, K; Oberlies, N, 2014) |
| "Children with mitochondrial disorders are frequently anesthetized for a wide range of operations." | 1.40 | Isoflurane anesthetic hypersensitivity and progressive respiratory depression in a mouse model with isolated mitochondrial complex I deficiency. ( Driessen, JJ; Manjeri, GR; Roelofs, S; Scheffer, GJ; Smeitink, JA; Willems, PH, 2014) |
| "Pretreatment with isoflurane prior to ischemia reduced LDH and CK-MB levels and infarct size, while it increased phosphorylation of ALDH2, which could be blocked by the ALDH2 inhibitor, cyanamide." | 1.39 | Isoflurane preconditioning confers cardioprotection by activation of ALDH2. ( Jin, JH; Lang, XE; Li, QS; Lv, JY; Wang, X; Zhang, KR, 2013) |
| "Isoflurane exposure was associated with weaker seizure-like electroencephalogram patterns than sevoflurane exposure." | 1.39 | Developmental effects of neonatal isoflurane and sevoflurane exposure in rats. ( Gravenstein, N; Martynyuk, AE; Pavlinec, C; Seubert, CN; Zhu, W, 2013) |
| "Here, we showed that isoflurane reduced brain infarct volumes and improved neurological functions of wild-type mice after a 90-min MCAO." | 1.39 | Glutamate transporter type 3 mediates isoflurane preconditioning-induced acute phase of neuroprotection in mice. ( Deng, J; Li, L; Zuo, Z, 2013) |
| "Opioid receptor antagonists increase hyperalgesia in humans and animals, which indicates that endogenous activation of opioid receptors provides relief from acute pain; however, the mechanisms of long-term opioid inhibition of pathological pain have remained elusive." | 1.39 | Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence. ( Corder, G; Donahue, RR; Doolen, S; He, Y; Hu, X; Jutras, BL; McCarson, KE; Mogil, JS; Storm, DR; Taylor, BK; Wang, ZJ; Wieskopf, JS; Winter, MK, 2013) |
| "Isoflurane treatment did not reduce brain edema compared with controls in any of the applied isoflurane concentrations." | 1.39 | Lower doses of isoflurane treatment has no beneficial effects in a rat model of intracerebral hemorrhage. ( Esposito, E; Lo, EH; Mandeville, ET, 2013) |
| "Isoflurane treatment was then combined with sphingosine-1-phosphate receptor-1/2 antagonist VPC23019 or sphingosine kinase 1/2 antagonist N,N-dimethylsphingosine." | 1.39 | Isoflurane post-treatment ameliorates GMH-induced brain injury in neonatal rats. ( Applegate, RL; Flores, JJ; Klebe, D; Krafft, PR; Leitzke, AS; Lekic, T; Rolland, WB; Van Allen, NR; Zhang, JH, 2013) |
| "Mouse models of global cerebral ischemia are essential tools to study the molecular mechanisms involved in ischemic brain damage." | 1.39 | Guidelines for using mouse global cerebral ischemia models. ( Hu, B; Kristian, T, 2013) |
| "Anaesthesia and genotype Alzheimer's disease had no impact on locomotor activity." | 1.39 | Effects of isoflurane-induced anaesthesia on cognitive performance in a mouse model of Alzheimer's disease: A randomised trial in transgenic APP23 mice. ( Blobner, M; Bogdanski, R; Eckel, B; Kochs, E; Ohl, F; Rammes, G; Starker, L, 2013) |
| "Morbid obesity affects the pharmacokinetics and pharmacodynamics of anesthetics, which may result in inappropriate dosing." | 1.38 | Determination of minimum alveolar concentration for isoflurane and sevoflurane in a rodent model of human metabolic syndrome. ( Britton, SL; Koch, LG; Lipinski, WJ; Lydic, R; Mashour, GA; Pal, D; Walton, ME, 2012) |
| "Cotreatment with trehalose reduces the levels of β amyloid peptide aggregates, tau plaques and levels of phospho-tau." | 1.38 | Trehalose protects from aggravation of amyloid pathology induced by isoflurane anesthesia in APP(swe) mutant mice. ( Casarejos, MJ; de Yébenes, JG; Gomez, A; Mena, MA; Perucho, J; Solano, RM, 2012) |
| "Temporary tinnitus is a common consequence of noise exposure, and may share important mechanisms with chronic tinnitus." | 1.38 | Isoflurane blocks temporary tinnitus. ( Norman, M; Tomscha, K; Wehr, M, 2012) |
| "Hemorrhagic shock was induced using a stepwise hemorrhage model in which 20%, 10%, and 10% of estimated blood volume were removed over three 30-minute periods and then 5% was removed every 30 minutes until the mean arterial pressure was less than 10 mm Hg." | 1.38 | Influence of progressive hemorrhage and subsequent cardiopulmonary resuscitation on the bispectral index during isoflurane anesthesia in a swine model. ( Kurita, T; Morita, K; Sato, S; Uraoka, M, 2012) |
| "Isoflurane has been used as an inhaled anaesthetic for nearly 30 years." | 1.37 | Effects of intrathecal isoflurane administration on nociception and Fos expression in the rat spinal cord. ( Duan, QZ; Li, YQ; Liu, CR; Wang, W; Wei, YY; Wu, SX; Xu, LX; Zhang, H, 2011) |
| "Bupivacaine 3." | 1.37 | Spinal anesthesia in infant rats: development of a model and assessment of neurologic outcomes. ( Athiraman, U; Berde, CB; Carpino, EA; Corfas, G; Soriano, SG; Yahalom, B; Zurakowski, D, 2011) |
| "In halothane-treated females, plasma concentration of tumor necrosis factor-alpha was greater than in males, and neutrophils were recruited to liver more rapidly and to a greater extent." | 1.36 | A mouse model of severe halothane hepatitis based on human risk factors. ( Dugan, CM; Ganey, PE; MacDonald, AE; Roth, RA, 2010) |
| " Small molecules with neurotrophic actions that are easy to synthesize and modify to improve bioavailability are needed." | 1.36 | Dopamine neuron stimulating actions of a GDNF propeptide. ( Ai, Y; Bradley, LH; Fuqua, J; Gash, DM; Gerhardt, GA; Glass, JD; Grondin, R; He, X; Huettl, P; Kelps, KA; Littrell, OM; Pomerleau, F; Richardson, A; Turchan-Cholewo, J; Zhang, Z, 2010) |
| "Paw inflammation was induced with 3% carrageenan and was measured with a plethysmometer at 30 minutes and 4, 8, and 24 hours after intraperitoneal injection." | 1.36 | Evaluation of the anti-inflammatory effects of ellagic acid. ( Corbett, S; Daniel, J; Drayton, R; Field, M; Garrett, N; Steinhardt, R, 2010) |
| " Accordingly, noninvasive, serial quantification of colonic inflammation could advantageously guide dosing regimens and assess drug efficacy, thus enhancing the value of colitis models in research." | 1.35 | Progression and variability of TNBS colitis-associated inflammation in rats assessed by contrast-enhanced and T2-weighted MRI. ( Hobson, AR; James, MF; Kruidenier, L; Lewis, HD; McCleary, S; Pohlmann, A; Robinson, A; Tilling, LC; Warnock, LC; Woolmer, O, 2009) |
| "Alzheimer's disease and other tauopathies are characterized by the presence of intracellular neurofibrillary tangles composed of hyperphosphorylated, insoluble tau." | 1.35 | Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia. ( Bretteville, A; Dickson, DW; Du, AL; Duff, KE; Liu, L; Planel, E; Virag, L; Whittington, RA; Yu, WH, 2009) |
| "10 min after CPR from 8 min of cardiac arrest 21 pigs were randomized to three groups (n=7/group) and then ventilated for 1h with gas mixtures as follows: (1) control: 30% O(2)+70% N(2); (2) Iso: 30% O(2)+69% N(2)+1% Iso; (3) Xe: 30% O(2)+70% Xe." | 1.35 | Early administration of xenon or isoflurane may not improve functional outcome and cerebral alterations in a porcine model of cardiac arrest. ( Coburn, M; Fries, M; Kottmann, K; Kuru, TH; Nolte, KW; Rossaint, R; Timper, A; Weis, J, 2009) |
| " The injection coordinates and the dosage of quinolinic acid were identical." | 1.35 | Ketamine anaesthesia interferes with the quinolinic acid-induced lesion in a rat model of Huntington's disease. ( Büchele, F; Döbrössy, M; Jiang, W; Nikkhah, G; Papazoglou, A, 2009) |
| "Neurogenic pulmonary edema (NPE) is an acute life-threatening complication following an injury of the spinal cord or brain, which is associated with sympathetic hyperactivity." | 1.35 | The role of nitric oxide in the development of neurogenic pulmonary edema in spinal cord-injured rats: the effect of preventive interventions. ( Hejcl, A; Kunes, J; Sedy, J; Syková, E; Zicha, J, 2009) |
| " Compared with ISO group alone, hepatic I/R combined with LPS resulted in severer liver injury, with the levels of ALT, AST in serum, MPO activity in the liver tissue, and hepatic and serum TNF-alpha level were all increased (all P<0." | 1.35 | [Isoflurane pretreatment reduced liver injury induced by ischemia/reperfusion combined with lipopolysaccharide in rats]. ( Huang, SD; Li, Q; Lv, X; Wu, FX; Yang, LQ; Yu, WF, 2008) |
| "Chrysin, a passion flower extract, may be beneficial because of its potential to attenuate surgical suppression of natural killer (NK) cell activity." | 1.35 | The effects of chrysin, a Passiflora incarnata extract, on natural killer cell activity in male Sprague-Dawley rats undergoing abdominal surgery. ( Beaumont, DM; Dixon, P; Garrett, N; Hills, R; Mark, TM; Veit, B, 2008) |
| "The pulmonary edema was elicited by an epidural thoracic balloon compression spinal cord lesion, performed under a low concentration of isoflurane (1." | 1.34 | A new model of severe neurogenic pulmonary edema in spinal cord injured rat. ( Hejcl, A; Jendelová, P; Likavcanová, K; Sedý, J; Syková, E; Urdzíková, L, 2007) |
| "We examined in a rabbit model of transient spinal cord ischemia (SCI) whether isoflurane (Iso) preconditioning induces ischemic tolerance to SCI in a dose-response manner, and whether this effect is dependent on mitochondrial adenosine triphosphate-dependent potassium (K(ATP)) channel." | 1.33 | Isoflurane preconditioning protects motor neurons from spinal cord ischemia: its dose-response effects and activation of mitochondrial adenosine triphosphate-dependent potassium channel. ( Hwang, JW; Jeon, YT; Kang, H; Kim, CS; Lim, SW; Oh, YS; Park, HP, 2005) |
| "Rats treated with isoflurane had the best cognitive recovery (p < 0." | 1.33 | Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats. ( Alexander, H; Clark, RS; Dixon, CE; Jenkins, L; Kochanek, PM; Statler, KD; Vagni, V, 2006) |
| "Halothane-pretreated animals were subjected to MCAO 24 hours after AP." | 1.31 | Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent. ( Dirnagl, U; Fütterer, C; Isaev, NK; Kapinya, KJ; Löwl, D; Maurer, M; Waschke, KF, 2002) |
| "Asphyxial cardiopulmonary arrest was induced and, after and 8 min cardiac arrest nonintervention interval, a standardized protocol of manual CPR with mechanical ventilation was performed." | 1.30 | Anesthetic regimen effects on a pediatric porcine model of asphyxial arrest. ( Ginn, A; Jasani, MS; Nadkarni, VM; Salzman, SK; Tice, LL, 1997) |
| "During warm (37 degrees) anoxia, Wisconsin solution preserved energy status; Krebs plus adenosine did not." | 1.29 | Energy status in anoxic rat hepatocytes: effects of isoflurane, solution composition, and hypothermia. ( Becker, GL; Howard, BJ; Landers, DF; Pohorecki, R, 1995) |
| "Bepridil is an investigational calcium antagonist that also has fast sodium channel blocking and antidysrhythmic properties." | 1.27 | Cardiac electrophysiologic interactions of bepridil, a new calcium antagonist, with enflurane, halothane, and isoflurane. ( Buben, JA; Hantler, CB; Knight, PR; Landau, SN; Larson, LO; Lucchesi, BR; Lynch, JJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (0.97) | 18.7374 |
| 1990's | 20 (6.45) | 18.2507 |
| 2000's | 78 (25.16) | 29.6817 |
| 2010's | 176 (56.77) | 24.3611 |
| 2020's | 33 (10.65) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, S | 2 |
| Liu, Y | 10 |
| Huang, S | 1 |
| Jin, F | 1 |
| Qi, F | 1 |
| Hofmann, C | 1 |
| Sander, A | 1 |
| Wang, XX | 2 |
| Buerge, M | 1 |
| Jungwirth, B | 1 |
| Borgstedt, L | 1 |
| Kreuzer, M | 1 |
| Kopp, C | 1 |
| Schorpp, K | 1 |
| Hadian, K | 1 |
| Wotjak, CT | 1 |
| Ebert, T | 1 |
| Ruitenberg, M | 1 |
| Parsons, CG | 1 |
| Rammes, G | 2 |
| Xu, DA | 1 |
| DeYoung, TP | 1 |
| Kondoleon, NP | 1 |
| Eckenhoff, RG | 2 |
| Eckenhoff, MF | 2 |
| Han, F | 1 |
| Zhao, J | 2 |
| Zhao, G | 1 |
| Steiger, C | 1 |
| Phan, NV | 1 |
| Huang, HW | 1 |
| Sun, H | 2 |
| Chu, JN | 1 |
| Reker, D | 1 |
| Gwynne, D | 1 |
| Collins, J | 1 |
| Tamang, S | 1 |
| McManus, R | 1 |
| Lopes, A | 1 |
| Hayward, A | 1 |
| Baron, RM | 1 |
| Kim, EY | 1 |
| Traverso, G | 1 |
| Zhang, W | 4 |
| Zhao, L | 4 |
| Zhang, J | 7 |
| Li, P | 1 |
| Lv, Z | 1 |
| Koutsogiannaki, S | 3 |
| Okuno, T | 2 |
| Kobayashi, Y | 1 |
| Ogawa, N | 1 |
| Yuki, K | 3 |
| Li, N | 3 |
| Zhang, X | 10 |
| Zhai, J | 1 |
| Yin, J | 3 |
| Ma, K | 1 |
| Wang, R | 2 |
| Qin, X | 1 |
| Li, Y | 10 |
| Dong, X | 5 |
| Wang, S | 2 |
| Wu, T | 2 |
| Li, M | 1 |
| Tian, L | 2 |
| Cong, P | 1 |
| Huang, X | 3 |
| Wu, H | 1 |
| Zhang, Q | 8 |
| Zhang, H | 6 |
| Xiong, L | 3 |
| Gu, C | 4 |
| Liu, J | 15 |
| Lin, C | 3 |
| Huang, J | 6 |
| Duan, W | 4 |
| Deng, Y | 5 |
| Ahmed, W | 3 |
| Li, R | 3 |
| Long, J | 3 |
| Khan, AA | 3 |
| Chen, L | 7 |
| Shpetko, YY | 1 |
| Filippenkov, IB | 1 |
| Denisova, AE | 1 |
| Stavchansky, VV | 1 |
| Gubsky, LV | 1 |
| Limborska, SA | 1 |
| Dergunova, LV | 1 |
| Li, Q | 6 |
| Mathena, RP | 1 |
| Li, F | 3 |
| Guan, Y | 1 |
| Mintz, CD | 1 |
| Abrahams, D | 1 |
| Ibrahim-Hashim, A | 1 |
| Ackerman, RS | 1 |
| Brown, JS | 1 |
| Whelan, CJ | 1 |
| Garfinkel, MB | 1 |
| Gatenby, RA | 1 |
| Muncey, AR | 1 |
| Liou, JY | 1 |
| Baird-Daniel, E | 1 |
| Zhao, M | 2 |
| Daniel, A | 1 |
| Schevon, CA | 1 |
| Ma, H | 1 |
| Schwartz, TH | 1 |
| Pang, X | 1 |
| Zhang, P | 2 |
| Zhou, Y | 7 |
| Liu, H | 5 |
| Wehrle, E | 1 |
| Tourolle Né Betts, DC | 1 |
| Kuhn, GA | 1 |
| Scheuren, AC | 1 |
| Hofmann, S | 1 |
| Müller, R | 1 |
| Wilkinson, CM | 1 |
| Kalisvaart, ACJ | 1 |
| Kung, TFC | 1 |
| Maisey, DR | 1 |
| Klahr, AC | 1 |
| Dickson, CT | 1 |
| Colbourne, F | 1 |
| Kovács, Z | 1 |
| Brunner, B | 1 |
| D'Agostino, DP | 1 |
| Ari, C | 1 |
| Liu, G | 1 |
| Qiao, S | 2 |
| Yu, Y | 3 |
| Hou, D | 1 |
| Swissa, E | 2 |
| Bar-Klein, G | 3 |
| Serlin, Y | 2 |
| Weissberg, I | 1 |
| Kamintsky, L | 2 |
| Eisenkraft, A | 2 |
| Statlender, L | 1 |
| Shrot, S | 1 |
| Rosman, Y | 2 |
| Prager, O | 1 |
| Friedman, A | 3 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 6 |
| Wang, J | 6 |
| Huang, L | 2 |
| Hu, K | 1 |
| Wang, H | 6 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 8 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 5 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 4 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 8 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 2 |
| Zhu, J | 2 |
| Jiang, H | 5 |
| He, C | 2 |
| Xiao, Z | 2 |
| Xu, J | 4 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 8 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 2 |
| Xu, G | 1 |
| Xu, N | 1 |
| Liu, S | 4 |
| He, H | 1 |
| Yang, M | 2 |
| Yang, Q | 2 |
| Duan, S | 1 |
| Han, J | 2 |
| Zhang, C | 3 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 3 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 10 |
| Yao, L | 2 |
| Sun, L | 4 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 3 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 3 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 8 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 3 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 12 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 6 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Gut Microbiome and Blood Indices in Patients With AD and Their Spousal Caregivers[NCT05601856] | 104 participants (Anticipated) | Observational | 2022-12-15 | Recruiting | |||
| Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury. A Randomized, Placebo-controlled, Double-blind Crossover Study[NCT02684669] | Phase 2 | 80 participants (Actual) | Interventional | 2016-02-29 | Completed | ||
| Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperal-gesia in Patients Following Recovery From Impacted Mandibular Third Molar Extraction. A Randomized, Placebo-controlled, Double-blind Crossover Study.[NCT02976337] | Phase 2 | 14 participants (Anticipated) | Interventional | 2017-10-12 | Recruiting | ||
| Association Between Prenatal Anesthesia Exposure and Neurodevelopmental Outcome : an Ambi-directional Cohort Study[NCT06052878] | 155 participants (Anticipated) | Observational [Patient Registry] | 2023-10-30 | Not yet recruiting | |||
| AnaConDa-therapy in COVID-19 Patients[NCT05586126] | 42 participants (Actual) | Observational | 2020-10-01 | Terminated (stopped due to Concerns about possible association between drug and increased ICU mortality) | |||
| Effect Of Dexmedetomidine Infusion On Sublingual Microcirculation In Patients Undergoing On Pump Coronary Artery Bypass Graft Surgery[NCT02714725] | Phase 4 | 70 participants (Anticipated) | Interventional | 2016-01-31 | Recruiting | ||
| Inhalatorial Sedation in Patient With SAH Versus Conventional Intravenous Sedation (GAS-SAH)[NCT00830843] | Phase 4 | 13 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| Epidural Anesthesia as an Alternative for Management in Acute Pancreatitis, a Randomised Clinical Trial[NCT02617199] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2015-11-30 | Recruiting | ||
| Phase 1 Study of Epidural Anesthesia on Pancreatic Perfusion and Clinical Outcome in Patients With Severe Acute Pancreatitis[NCT01607996] | Phase 1 | 35 participants (Actual) | Interventional | 2005-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for isoflurane and Disease Models, Animal
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Cardiovascular responses to sevoflurane: a review.
Topics: Adult; Anesthetics, Inhalation; Animals; Baroreflex; Blood Pressure; Cardiovascular System; Cerebrov | 1995 |
The organ toxicity of inhaled anesthetics.
Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Disease Models | 1995 |
5 trials available for isoflurane and Disease Models, Animal
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
The effect of xenon on isoflurane protection against experimental myocardial infarction.
Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Female; Ischemic Preconditioning, Myocar | 2009 |
Ventricular arrhythmias and mortality associated with isoflurane and sevoflurane in a porcine model of myocardial infarction.
Topics: Anesthetics, Inhalation; Animal Welfare; Animals; Arrhythmias, Cardiac; Disease Models, Animal; Fema | 2011 |
Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model.
Topics: Anesthesia; Anesthetics; Animals; Blood Pressure; Brain Edema; Brain Injuries; Cerebral Infarction; | 2013 |
Decreased mortality in a rat model of acute postinfarction heart failure.
Topics: Amiodarone; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Critical Care; Diseas | 2006 |
303 other studies available for isoflurane and Disease Models, Animal
| Article | Year |
|---|---|
Sevoflurane and isoflurane inhibit KCl-induced, Rho kinase-mediated, and PI3K-participated vasoconstriction in aged diabetic rat aortas.
Topics: Aging; Amides; Anesthetics, Inhalation; Animals; Aorta; Chromones; Diabetes Mellitus, Experimental; | 2021 |
Inhalational Anesthetics Do Not Deteriorate Amyloid-β-Derived Pathophysiology in Alzheimer's Disease: Investigations on the Molecular, Neuronal, and Behavioral Level.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Disease Models, Animal; | 2021 |
Anesthetic Effects on the Progression of Parkinson Disease in the Rat DJ-1 Model.
Topics: Anesthetics, Inhalation; Animals; Behavior, Animal; Calcium-Binding Proteins; Disease Models, Animal | 2021 |
Prolonged Volatile Anesthetic Exposure Exacerbates Cognitive Impairment and Neuropathology in the 5xFAD Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Anesthetics, Inhalation; Animals; Cognitive Dysfunction; Disease Models, Animal; | 2021 |
Dynamic Monitoring of Systemic Biomarkers with Gastric Sensors.
Topics: Acute Kidney Injury; Anesthetics, Inhalation; Animals; Biomarkers; Disease Models, Animal; Gastric J | 2021 |
Metformin improves cognitive impairment in diabetic mice induced by a combination of streptozotocin and isoflurane anesthesia.
Topics: Anesthesia; Animals; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Disease Models, Animal; | 2021 |
Isoflurane attenuates sepsis-associated lung injury.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Animals; Chemotaxis; Disease Models, Animal; Eicosanoids | 2022 |
Isoflurane and Netrin-1 combination therapy enhances angiogenesis and neurological recovery by improving the expression of HIF-1α-Netrin-1-UNC5B/VEGF cascade to attenuate cerebral ischemia injury.
Topics: Animals; Brain Injuries; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Hypoxia-Induci | 2022 |
A modified mouse model of perioperative neurocognitive disorders exacerbated by sleep fragmentation.
Topics: Aging; Animals; Disease Models, Animal; Isoflurane; Memory Disorders; Mice; Neurocognitive Disorders | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Isoflurane Anesthesia's Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model.
Topics: Anesthesia; Animals; Brain; Disease Models, Animal; Gene Expression; Gene Expression Regulation; Isc | 2023 |
Effects of Early Exposure to Isoflurane on Susceptibility to Chronic Pain Are Mediated by Increased Neural Activity Due to Actions of the Mammalian Target of the Rapamycin Pathway.
Topics: Anesthetics, General; Animals; Chronic Pain; Disease Models, Animal; Isoflurane; Mammals; Mice; Neur | 2023 |
Immunomodulatory and pro-oncologic effects of ketamine and isoflurane anesthetics in a murine model.
Topics: Anesthetics; Anesthetics, Inhalation; Animals; Disease Models, Animal; Immunity; Isoflurane; Ketamin | 2023 |
Burst suppression uncovers rapid widespread alterations in network excitability caused by an acute seizure focus.
Topics: 4-Aminopyridine; Animals; Brain; Disease Models, Animal; Electroencephalography; Isoflurane; Male; N | 2019 |
Dexmedetomidine pretreatment attenuates isoflurane-induced neurotoxicity via inhibiting the TLR2/NF-κB signaling pathway in neonatal rats.
Topics: Anesthetics; Animals; Animals, Newborn; Apoptosis; Dexmedetomidine; Disease Models, Animal; Hippocam | 2020 |
Evaluation of longitudinal time-lapsed in vivo micro-CT for monitoring fracture healing in mouse femur defect models.
Topics: Adaptor Proteins, Signal Transducing; Anesthesia, Inhalation; Animals; Bone and Bones; Bone Remodeli | 2019 |
The collagenase model of intracerebral hemorrhage in awake, freely moving animals: The effects of isoflurane.
Topics: Animals; Blood Glucose; Cerebral Hemorrhage; Collagenases; Disease Models, Animal; Electroencephalog | 2020 |
Inhibition of adenosine A1 receptors abolished the nutritional ketosis-evoked delay in the onset of isoflurane-induced anesthesia in Wistar Albino Glaxo Rijswijk rats.
Topics: Adenosine A1 Receptor Antagonists; Anesthesia; Anesthetics, Inhalation; Animals; Disease Models, Ani | 2020 |
Isoflurane improves cerebral ischemia-reperfusion injury in rats via activating MAPK signaling pathway.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Isoflurane; MAP Kinase Signaling System; Rats; Repe | 2021 |
Midazolam and isoflurane combination reduces late brain damage in the paraoxon-induced status epilepticus rat model.
Topics: Animals; Anticonvulsants; Brain; Disease Models, Animal; Isoflurane; Male; Midazolam; Paraoxon; Rats | 2020 |
Isoflurane Exposure in Juvenile Caenorhabditis elegans Causes Persistent Changes in Neuron Dynamics.
Topics: Anesthetics, Inhalation; Animals; Behavior, Animal; Caenorhabditis elegans; Disease Models, Animal; | 2020 |
Ageing and genetic background influence anaesthetic effects in a D. melanogaster model of blunt trauma with brain injury
Topics: Aging; Anesthetics, Inhalation; Animals; Brain; Brain Injuries, Traumatic; Disease Models, Animal; D | 2020 |
Isoflurane versus sevoflurane for early brain injury and expression of sphingosine kinase 1 after experimental subarachnoid hemorrhage.
Topics: Animals; Apoptosis; Brain Edema; Disease Models, Animal; Isoflurane; Male; Mice; Neuroprotective Age | 2020 |
Lack of antidepressant effects of burst-suppressing isoflurane anesthesia in adult male Wistar outbred rats subjected to chronic mild stress.
Topics: Anesthetics, Inhalation; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depressi | 2020 |
Effects of PYRIN-containing Apaf1-like protein 1 on isoflurane-induced postoperative cognitive dysfunction in aged rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Disease Models, Animal; Gene Silencing; Hippocampus; Inflam | 2020 |
MiR-21-5p but not miR-1-3p expression is modulated by preconditioning in a rat model of myocardial infarction.
Topics: Animals; Apoptosis Regulatory Proteins; Disease Models, Animal; Heme Oxygenase-1; Hypoxia-Inducible | 2020 |
Interactions among Genetic Background, Anesthetic Agent, and Oxygen Concentration Shape Blunt Traumatic Brain Injury Outcomes in
Topics: Anesthetics, Inhalation; Animals; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Drosophi | 2020 |
Role of Endothelial Nitric Oxide Synthase in Isoflurane Conditioning-Induced Neurovascular Protection in Subarachnoid Hemorrhage.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Disease Models, Animal; Endothelium, Vascular; Isc | 2020 |
Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device.
Topics: Acute Lung Injury; Anesthesia; Anesthetics; Animals; Blood Gas Analysis; Capillary Permeability; Dis | 2020 |
Anesthetic and subanesthetic doses of isoflurane conditioning provides strong protection against delayed cerebral ischemia in a mouse model of subarachnoid hemorrhage.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Isoflurane; Male; Mice; Mice, | 2021 |
Isoflurane reduces septic neuron injury by HO‑1‑mediated abatement of inflammation and apoptosis.
Topics: Animals; Apoptosis; Disease Models, Animal; Heme Oxygenase-1; Inflammation; Isoflurane; Male; Membra | 2021 |
Role of SIRT1 in Isoflurane Conditioning-Induced Neurovascular Protection against Delayed Cerebral Ischemia Secondary to Subarachnoid Hemorrhage.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Fluorescent Antibody Technique; Gene Expression; Is | 2021 |
Role of Unfolded Protein Response and Endoplasmic Reticulum-Associated Degradation by Repeated Exposure to Inhalation Anesthetics in
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Caenorhabditis elegans; Caenorhabditis elegan | 2021 |
Isoflurane upregulates microRNA-9-3p to protect rats from hepatic ischemia-reperfusion injury through inhibiting fibronectin type III domain containing 3B.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Disease Models, Animal; Fibronectins; Ge | 2021 |
Prolonged isoflurane anesthesia-induced acidosis decreases penile intracavernous pressure in rats.
Topics: Acidosis; Anesthetics, Inhalation; Animals; Arterial Pressure; Disease Models, Animal; Electric Stim | 2022 |
Sub-anesthesia Dose of Isoflurane in 60% Oxygen Reduces Inflammatory Responses in Experimental Sepsis Models.
Topics: Adult; Anesthesia; Animals; Blotting, Western; Bronchoalveolar Lavage Fluid; Disease Models, Animal; | 2017 |
Imaging blood-brain barrier dysfunction as a biomarker for epileptogenesis.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Angiotensin II Type 1 Receptor Blockers; Animals; B | 2017 |
Brief isoflurane anesthesia regulates striatal AKT-GSK3β signaling and ameliorates motor deficits in a rat model of early-stage Parkinson's disease.
Topics: Anesthesia; Animals; Corpus Striatum; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; | 2017 |
Isoflurane preconditioning inhibits the effects of tissue-type plasminogen activator on brain endothelial cell in an
Topics: Animals; Apoptosis; Brain Injuries; Brain Ischemia; Culture Media, Conditioned; Cyclooxygenase 2; Di | 2017 |
Duration of isoflurane-based surgical anesthesia determines severity of brain injury and neurological deficits after a transient focal ischemia in young adult rats.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Brain; Disease Models, Animal; Infarction, Middle Cere | 2017 |
Characteristics of electromechanical window in anesthetized rabbit models of short QT and long QT syndromes.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Benzopyrans; Biomarkers; Biomarkers, Pharmacological; Cro | 2017 |
Brief isoflurane administration as a post-exposure treatment for organophosphate poisoning.
Topics: Amygdala; Anesthetics, Inhalation; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; | 2017 |
Inhibition of p75 neurotrophin receptor does not rescue cognitive impairment in adulthood after isoflurane exposure in neonatal mice.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cognition Disorders; Disease Models, Animal; Fem | 2017 |
Isoflurane exposure for three hours triggers apoptotic cell death in neonatal macaque brain.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Brain; Disease Models, Animal; Female | 2017 |
Thermal A-δ Nociceptors, Identified by Transcriptomics, Express Higher Levels of Anesthesia-Sensitive Receptors Than Thermal C-Fibers and Are More Suppressible by Low-Dose Isoflurane.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Behavior, Animal; Disease Models, Anim | 2018 |
Activation of cannabinoid receptor 1 is involved in protection against mitochondrial dysfunction and cerebral ischaemic tolerance induced by isoflurane preconditioning.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Disease Models, Animal; Infarction, Middle Cerebra | 2017 |
Persistent isoflurane-induced hypotension causes hippocampal neuronal damage in a rat model of chronic cerebral hypoperfusion.
Topics: Animals; Brain Ischemia; CA1 Region, Hippocampal; Disease Models, Animal; Hippocampus; Hypotension; | 2018 |
Isoflurane and the Analgesic Effect of Acupuncture and Electroacupuncture in an Animal Model of Neuropathic Pain.
Topics: Acupuncture Analgesia; Analgesics; Animals; Disease Models, Animal; Electroacupuncture; Isoflurane; | 2018 |
The Effect of Mitochondrial Complex I-Linked Respiration by Isoflurane Is Independent of Mitochondrial Nitric Oxide Production.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Isof | 2018 |
Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment.
Topics: Aging; Amino Acid Chloromethyl Ketones; Anesthetics, Inhalation; Animals; Caspase 1; Cell Line, Tran | 2018 |
Intracranial Space-occupying Lesion Inducing Intracranial Hypertension Increases the Encephalographic Effects of Isoflurane in a Swine Model.
Topics: Anesthetics, Inhalation; Animals; Brain Neoplasms; Disease Models, Animal; Electroencephalography; I | 2019 |
Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis.
Topics: Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Apoptosis; bcl-2-Associated X Protein; Brai | 2018 |
Vascular endothelial growth factor regulation of endothelial nitric oxide synthase phosphorylation is involved in isoflurane cardiac preconditioning.
Topics: Animals; Cell Communication; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Endothel | 2019 |
Sirt1 mediates improvement of isoflurane-induced memory impairment following hyperbaric oxygen preconditioning in middle-aged mice.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Gene Knockdown Techniques; Heme Oxygenase- | 2018 |
BACE1 gene silencing alleviates isoflurane anesthesia‑induced postoperative cognitive dysfunction in immature rats by activating the PI3K/Akt signaling pathway.
Topics: Amyloid Precursor Protein Secretases; Anesthetics, Inhalation; Animals; Apoptosis; Aspartic Acid End | 2018 |
Inflammation caused by peripheral immune cells across into injured mouse blood brain barrier can worsen postoperative cognitive dysfunction induced by isoflurane.
Topics: Animals; Blood-Brain Barrier; CD4-Positive T-Lymphocytes; Cognitive Dysfunction; Disease Models, Ani | 2018 |
Comparison of inhaled versus intravenous anesthesia for laryngoscopy and laryngeal electromyography in a rat model.
Topics: Anesthesia, Intravenous; Anesthetics, Inhalation; Animals; Disease Models, Animal; Electromyography; | 2018 |
Longitudinal assessment of cerebral perfusion and vascular response to hypoventilation in a bigenic mouse model of Alzheimer's disease with amyloid and tau pathology.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Anesthesia; Animals; Brain; Carbon Dioxide; Disea | 2019 |
Volatile Anesthetic Attenuates Phagocyte Function and Worsens Bacterial Loads in Wounds.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Bacterial Load; Cardi | 2019 |
Propofol attenuates postoperative hyperalgesia via regulating spinal GluN2B-p38MAPK/EPAC1 pathway in an animal model of postoperative pain.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Disease Models, Animal; Guanine Nucleoti | 2019 |
Nitric Oxide Donor Prevents Neonatal Isoflurane-induced Impairments in Synaptic Plasticity and Memory.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Disease Models, Animal; Female; Isoflurane; Male | 2019 |
Effect of isoflurane on myocardial ischemia-reperfusion injury through the p38 MAPK signaling pathway.
Topics: Administration, Inhalation; Animals; Disease Models, Animal; Heart Function Tests; Isoflurane; Male; | 2019 |
Relevance of experimental paradigms of anesthesia induced neurotoxicity in the mouse.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Behavior, Animal; Disease Models, Animal; Haplor | 2019 |
Mechanism of Emulsified Isoflurane Postconditioning-Induced Activation of the Nrf2-Antioxidant Response Element Signaling Pathway During Myocardial Ischemia-Reperfusion: The Relationship With Reactive Oxygen Species.
Topics: Animals; Antioxidant Response Elements; Antioxidants; Disease Models, Animal; Emulsions; Heme Oxygen | 2019 |
Mouse model of severe recessive RYR1-related myopathy.
Topics: Animals; Calcium; Disease Models, Animal; DNA Mutational Analysis; Gene Editing; Gene Expression Reg | 2019 |
Adiponectin improves isoflurane-induced cognitive dysfunction in elderly rats via inhibiting p38-MAPK signal pathway in hippocampus.
Topics: Adiponectin; Aging; Animals; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Isoflurane; | 2019 |
The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury.
Topics: 5'-Nucleotidase; Acute Kidney Injury; Adenosine; Anesthetics, Inhalation; Animals; Antibodies, Neutr | 2013 |
Isoflurane preconditioning confers cardioprotection by activation of ALDH2.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Cardiotonic Agents; Creatine | 2013 |
Depression of neuronal activity by sedatives is associated with adverse effects after brain injury.
Topics: Analysis of Variance; Animals; Brain Injuries; Disease Models, Animal; Electroencephalography; Hypno | 2013 |
Early stimulation treatment provides complete sensory-induced protection from ischemic stroke under isoflurane anesthesia.
Topics: Anesthetics, Inhalation; Animals; Cerebral Cortex; Disease Models, Animal; Infarction, Middle Cerebr | 2013 |
Xenon neurotoxicity in rat hippocampal slice cultures is similar to isoflurane and sevoflurane.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cell Death; Disease Models, Animal; Dose-Respons | 2013 |
Emulsified isoflurane protects rat heart in situ after regional ischemia and reperfusion.
Topics: Anesthetics, Inhalation; Animals; Cytochromes c; Disease Models, Animal; Emulsions; Energy Metabolis | 2014 |
Developmental effects of neonatal isoflurane and sevoflurane exposure in rats.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Behavior, Animal; Disease Models, Animal; Electr | 2013 |
Apolipoprotein A-1 mimetic D-4F enhances isoflurane-induced eNOS signaling and cardioprotection during acute hyperglycemia.
Topics: Acute Disease; Animals; Apolipoprotein A-I; Blood Glucose; Caveolin 1; Cells, Cultured; Coronary Ves | 2013 |
Isoflurane in contrast to propofol promotes fluid extravasation during cardiopulmonary bypass in pigs.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cardiopulmonary Bypass; Disease Models, | 2013 |
Glutamate transporter type 3 mediates isoflurane preconditioning-induced acute phase of neuroprotection in mice.
Topics: Animals; Brain Infarction; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; | 2013 |
Isoflurane post-conditioning stimulates the proliferative phase of myocardial recovery in an ischemia-reperfusion model of heart injury in rats.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Female; Ischemic Postconditioning; Isoflur | 2014 |
Volatile anesthetics improve survival after cecal ligation and puncture.
Topics: Anesthetics, Inhalation; Animals; Cecum; Desflurane; Disease Models, Animal; Inflammation; Isofluran | 2013 |
Isoflurane post-treatment improves pulmonary vascular permeability via upregulation of heme oxygenase-1.
Topics: Acute Lung Injury; Animals; Capillary Permeability; Disease Models, Animal; Heme Oxygenase-1; Isoflu | 2013 |
Cyclosporine A at reperfusion fails to reduce infarct size in the in vivo rat heart.
Topics: Anesthetics, Inhalation; Animals; Cyclosporine; Disease Models, Animal; Enzyme Inhibitors; Ischemic | 2013 |
The impact of four different classes of anesthetics on the mechanisms of blood pressure regulation in normotensive and spontaneously hypertensive rats.
Topics: Anesthetics; Anesthetics, Combined; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressur | 2013 |
Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.
Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Anima | 2013 |
Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.
Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Anima | 2013 |
Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.
Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Anima | 2013 |
Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.
Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Anima | 2013 |
Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice.
Topics: Aging; Alzheimer Disease; Analysis of Variance; Anesthetics, Inhalation; Animals; Desflurane; Diseas | 2014 |
Lower doses of isoflurane treatment has no beneficial effects in a rat model of intracerebral hemorrhage.
Topics: Anesthetics, Inhalation; Animals; Brain; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; D | 2013 |
Isoflurane post-treatment ameliorates GMH-induced brain injury in neonatal rats.
Topics: Animals; Animals, Newborn; Brain; Disease Models, Animal; Intracranial Hemorrhages; Isoflurane; Neur | 2013 |
Isoflurane-induced apoptosis of neurons and oligodendrocytes in the fetal rhesus macaque brain.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Brain; Disease Models, Animal; Female | 2014 |
Optimization of a pain model: effects of body temperature and anesthesia on bladder nociception in mice.
Topics: Anesthesia; Animals; Body Temperature; Disease Models, Animal; Electrophysiological Phenomena; Femal | 2013 |
Musk shrews selectively bred for motion sickness display increased anesthesia-induced vomiting.
Topics: Animals; Breeding; Copper Sulfate; Disease Models, Animal; Emetics; Female; Isoflurane; Male; Motion | 2014 |
Isoflurane suppresses cortical spreading depolarizations compared to propofol--implications for sedation of neurocritical care patients.
Topics: Animals; Cerebrovascular Circulation; Cortical Spreading Depression; Disease Models, Animal; Dose-Re | 2014 |
Guidelines for using mouse global cerebral ischemia models.
Topics: Animals; Blood Pressure; Brain; Brain Damage, Chronic; Brain Ischemia; Disease Models, Animal; Heart | 2013 |
Cardioprotection during diabetes: the role of mitochondrial DNA.
Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; | 2014 |
Isoflurane anesthetic hypersensitivity and progressive respiratory depression in a mouse model with isolated mitochondrial complex I deficiency.
Topics: Anesthesia; Anesthetics; Animals; Disease Models, Animal; Electron Transport Complex I; Female; Isof | 2014 |
Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke.
Topics: Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Brain Ischemia; Cerebrovascular Circulation; | 2014 |
Evidence for the use of isoflurane as a replacement for chloral hydrate anesthesia in experimental stroke: an ethical issue.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Bioethical Issues; Chloral Hydrate; Disease Models, An | 2014 |
Intravenous pretreatment with emulsified isoflurane preconditioning protects kidneys against ischemia/reperfusion injury in rats.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Emulsions; Inflammation; Ischemic | 2014 |
Critical role of inflammatory cytokines in impairing biochemical processes for learning and memory after surgery in rats.
Topics: Animals; Carotid Arteries; Cytokines; Disease Models, Animal; Gene Expression Regulation; Hippocampu | 2014 |
[The effects of preconditioning and postconditioning with isoflurane on focal cerebral ischemi/reperfusion injury in rats].
Topics: Animals; Brain; Brain Ischemia; Disease Models, Animal; Interleukin-1beta; Ischemic Postconditioning | 2014 |
Effects of repetitive exposure to anesthetics and analgesics in the Tg2576 mouse Alzheimer's model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analgesics; Anesthetics; A | 2014 |
Inhibition of brain ischemia-caused notch activation in microglia may contribute to isoflurane postconditioning-induced neuroprotection in male rats.
Topics: Animals; Brain; Brain Ischemia; Caspase 3; CD11b Antigen; Cell Hypoxia; Cell Line; Cytokines; Diseas | 2014 |
The Role of SUMO-Conjugating Enzyme Ubc9 in the Neuroprotection of Isoflurane Preconditioning Against Ischemic Neuronal Injury.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Disease Models, Animal; Humans; Ischemic Precondit | 2015 |
The role of hippocampal tau protein phosphorylation in isoflurane-induced cognitive dysfunction in transgenic APP695 mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Cognition; Cognition D | 2014 |
Isoflurane reduces the ischemia reperfusion injury surge: a longitudinal study with MRI.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Diffusion Magnetic Resonance Imaging; Diseas | 2014 |
Cardioprotective effects of isoflurane in a rat model of stress-induced cardiomyopathy (takotsubo).
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Isoflurane; Random Allocation; Rats; Rats, Spra | 2014 |
Isoflurane postconditioning improved long-term neurological outcome possibly via inhibiting the mitochondrial permeability transition pore in neonatal rats after brain hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Atractyloside; CA3 Region, Hippocampal; Carotid Artery, Common; Central N | 2014 |
Sustained increase in α5GABAA receptor function impairs memory after anesthesia.
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Cognition Disorders; Disease Models, Animal; | 2014 |
Region-specific effects of isoflurane anesthesia on Fos immunoreactivity in response to intravenous cocaine challenge in rats with a history of repeated cocaine administration.
Topics: Anesthetics, Inhalation; Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; | 2015 |
Response to "Cardioprotective effect of isoflurane anesthesia from takotsubo syndrome and its implications".
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Isoflurane; Takotsubo Cardiomyopathy; Ultrasono | 2014 |
Cardioprotective effect of isoflurane anesthesia from Takotsubo syndrome and its implications.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Isoflurane; Takotsubo Cardiomyopathy; Ultrasono | 2014 |
Comparison of isoflurane and α-chloralose in an anesthetized swine model of acute pulmonary embolism producing right ventricular dysfunction.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Biomarkers; Blood Pressure; Cardiac Output; Chloralose | 2015 |
Protective role of isoflurane pretreatment in rats with focal cerebral ischemia and the underlying molecular mechanism.
Topics: Animals; Astrocytes; Brain Injuries; Brain Ischemia; Disease Models, Animal; Humans; Infarction, Mid | 2015 |
Preconditioning cortical lesions reduce the incidence of peri-infarct depolarizations during focal ischemia in the Spontaneously Hypertensive Rat: interaction with prior anesthesia and the impact of hyperglycemia.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cerebellar Cortex; Cerebral | 2015 |
Isoflurane anesthesia initiated at the onset of reperfusion attenuates oxidative and hypoxic-ischemic brain injury.
Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Cerebrovascular Circulation; Disease Models, A | 2015 |
Methodology of motor evoked potentials in a rabbit model.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Apnea; Disease Models, Animal; Evoked Po | 2015 |
Isoflurane preconditioning provides neuroprotection against stroke by regulating the expression of the TLR4 signalling pathway to alleviate microglial activation.
Topics: Animals; Apoptosis; Biomarkers; Brain Infarction; Cells, Cultured; Chaperonin 60; Disease Models, An | 2015 |
Sevoflurane Induces DNA Damage Whereas Isoflurane Leads to Higher Antioxidative Status in Anesthetized Rats.
Topics: Anesthetics, Inhalation; Animals; Antioxidants; Disease Models, Animal; DNA Damage; Isoflurane; Male | 2015 |
Endoplasmic reticulum stress pathway mediates isoflurane-induced neuroapoptosis and cognitive impairments in aged rats.
Topics: Activating Transcription Factors; Aging; Anesthetics, Inhalation; Animals; Apoptosis; Cognition Diso | 2015 |
Potential of the ovine brain as a model for anesthesia-induced neuroapoptosis.
Topics: Animals; Apoptosis; Brain; Dexmedetomidine; Disease Models, Animal; Feasibility Studies; Hernias, Di | 2015 |
Increased mitochondrial ATP production capacity in brain of healthy mice and a mouse model of isolated complex I deficiency after isoflurane anesthesia.
Topics: Adenosine Triphosphate; Anesthesia; Animals; Brain; Disease Models, Animal; Electron Transport Compl | 2016 |
Glycyrrhizin attenuates isoflurane-induced cognitive deficits in neonatal rats via its anti-inflammatory activity.
Topics: Anesthetics; Animals; Animals, Newborn; Anti-Inflammatory Agents; Apoptosis; Cognition Disorders; Di | 2016 |
Swimming exercise ameliorates neurocognitive impairment induced by neonatal exposure to isoflurane and enhances hippocampal histone acetylation in mice.
Topics: Acetylation; Anesthetics; Animals; Animals, Newborn; Blood Glucose; Cognition Disorders; Disease Mod | 2016 |
Cardioprotection from emulsified isoflurane postconditioning is lost in rats with streptozotocin-induced diabetes due to the impairment of Brg1/Nrf2/STAT3 signalling.
Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA Helicases; Ischemic Postcondit | 2016 |
Emulsified Isoflurane Protects Against Transient Focal Cerebral Ischemia Injury in Rats via the PI3K/Akt Signaling Pathway.
Topics: Administration, Intravenous; Animals; Anti-Inflammatory Agents; Brain; Chemistry, Pharmaceutical; Cy | 2016 |
BDNF pathway is involved in the protective effects of SS-31 on isoflurane-induced cognitive deficits in aging mice.
Topics: Aging; Anesthetics, Inhalation; Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; D | 2016 |
Isoflurane preconditioning protects rat brain from ischemia reperfusion injury via up-regulating the HIF-1α expression through Akt/mTOR/s6K activation.
Topics: Animals; Apoptosis; Blotting, Western; Brain; Cell Line; Cell Survival; Disease Models, Animal; Hypo | 2016 |
Dorsal Root Ganglion Infiltration by Macrophages Contributes to Paclitaxel Chemotherapy-Induced Peripheral Neuropathy.
Topics: Anesthetics; Animals; Antibodies; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineopl | 2016 |
Inhaled Anesthetics Exert Different Protective Properties in a Mouse Model of Ventilator-Induced Lung Injury.
Topics: Anesthetics, Inhalation; Animals; Anti-Inflammatory Agents; Antioxidants; Bronchoalveolar Lavage Flu | 2016 |
Peri-infarct depolarizations during focal ischemia in the awake Spontaneously Hypertensive Rat. Minimizing anesthesia confounds in experimental stroke.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Infarctio | 2016 |
Adding Emulsified Isoflurane to Cardioplegia Solution Produces Cardiac Protection in a Dog Cardiopulmonary Bypass Model.
Topics: Animals; bcl-2-Associated X Protein; Cardioplegic Solutions; Cardiopulmonary Bypass; Creatine Kinase | 2016 |
[Electroacupuncture Intervention Inhibits the Decline of Learning-memory Ability and Overex- pression of Cleaved Caspase-3 and Bax in Hippocampus Induced by Isoflurane in APPswe/PS 1].
Topics: Alzheimer Disease; Animals; bcl-2-Associated X Protein; Caspase 3; Disease Models, Animal; Electroac | 2016 |
Subanesthetic isoflurane relieves zymosan-induced neutrophil inflammatory response by targeting NMDA glutamate receptor and Toll-like receptor 2 signaling.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Capillary Permeability; Cells, Cultured; Disea | 2016 |
Electroencephalographic signatures of pain and analgesia in rats.
Topics: Anesthetics, Inhalation; Animals; Brain Waves; Cerebral Cortex; Disease Models, Animal; Electroencep | 2016 |
Neuroprotective effect of ginsenoside Rg1 prevents cognitive impairment induced by isoflurane anesthesia in aged rats via antioxidant, anti-inflammatory and anti-apoptotic effects mediated by the PI3K/AKT/GSK-3β pathway.
Topics: Age Factors; Anesthetics, Inhalation; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Bi | 2016 |
Single and repeated exposures to the volatile anesthetic isoflurane do not impair operant performance in aged rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Conditioning, Operant; Disease Models, Animal; Drug Adminis | 2016 |
Isoflurane-induced inactivation of CREB through histone deacetylase 4 is responsible for cognitive impairment in developing brain.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Brain; Cognition Disorders; CREB-Binding Protein | 2016 |
Dissociation of metabolic and hemodynamic levodopa responses in the 6-hydroxydopamine rat model.
Topics: Analgesics; Animals; Antiparkinson Agents; Cerebrovascular Circulation; Disease Models, Animal; Fema | 2016 |
Isoflurane anesthesia exacerbates learning and memory impairment in zinc-deficient APP/PS1 transgenic mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Anesthetics, Inhalation; Animals; Apoptosis; Cere | 2016 |
Long-term Fate Mapping to Assess the Impact of Postnatal Isoflurane Exposure on Hippocampal Progenitor Cell Productivity.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Cell Death; Cell Proliferation; Disease Models, Animal; | 2016 |
Effects of pentobarbital, isoflurane, or medetomidine-midazolam-butorphanol anesthesia on bronchoalveolar lavage fluid and blood chemistry in rats.
Topics: Administration, Inhalation; Analgesics, Opioid; Anesthesia; Anesthetics, Inhalation; Animals; Biomar | 2016 |
Isoflurane prevents acquired epilepsy in rat models of temporal lobe epilepsy.
Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Electrocorticography; Epilepsy, Temporal Lobe; | 2016 |
Isoflurane neurotoxicity involves activation of hypoxia inducible factor-1α via intracellular calcium in neonatal rodents.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Calcium; Calcium Signaling; Cells, Cu | 2016 |
Isoflurane Impairs Motor Function Recovery by Increasing Neuroapoptosis and Degeneration During Spinal Ischemia-Reperfusion Injury in Rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Calcium-Binding Proteins; Caspase 3; Disease Models, An | 2017 |
From the Cover: Prolonged Exposure to Volatile Anesthetic Isoflurane Worsens the Outcome of Polymicrobial Abdominal Sepsis.
Topics: Anesthetics, Inhalation; Animals; Cytokines; Disease Models, Animal; Isoflurane; Lymphocyte Function | 2017 |
Influence of Volatile Anesthesia on the Release of Glutamate and other Amino Acids in the Nucleus Accumbens in a Rat Model of Alcohol Withdrawal: A Pilot Study.
Topics: Amino Acids; Anesthesia, Inhalation; Animals; Arginine; Aspartic Acid; Desflurane; Disease Models, A | 2017 |
Hemodynamic effects of intraoperative anesthetics administration in photothrombotic stroke model: a study using laser speckle imaging.
Topics: Anesthetics, Inhalation; Animals; Brain; Brain Ischemia; Disease Models, Animal; Hemodynamics; Isofl | 2017 |
Anaesthetic-induced cardioprotection in an experimental model of the Takotsubo syndrome - isoflurane vs. propofol.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Disease Models, Animal; Echocardiography | 2017 |
Anti-RAGE antibody attenuates isoflurane-induced cognitive dysfunction in aged rats.
Topics: Aging; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Blood-Br | 2017 |
Anesthesia-Induced Hypothermia Attenuates Early-Phase Blood-Brain Barrier Disruption but Not Infarct Volume following Cerebral Ischemia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Arterial Occlusive Diseases; Blood-Brain B | 2017 |
Repeated remote ischemic preconditioning and isoflurane anesthesia in an experimental model of renal ischemia-reperfusion injury.
Topics: Animals; Creatinine; Disease Models, Animal; Ischemic Preconditioning; Isoflurane; Kidney; Male; Pro | 2017 |
Histamine H3 Receptor Antagonist Prevents Memory Deficits and Synaptic Plasticity Disruption Following Isoflurane Exposure.
Topics: Anesthetics, Inhalation; Animals; Avoidance Learning; Disease Models, Animal; Hippocampus; Histamine | 2017 |
Global reduction of information exchange during anesthetic-induced unconsciousness.
Topics: Anesthetics, Inhalation; Animals; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationshi | 2017 |
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors participate in the analgesic but not hypnotic effects of emulsified halogenated anaesthetics.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Anesthetics, Inhalation; Anima | 2008 |
Estradiol attenuates neuroprotective benefits of isoflurane preconditioning in ischemic mouse brain.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Drug Implants; Estradiol; Estrogen Receptor alpha; | 2008 |
Establishment of a porcine right ventricular infarction model for cardioprotective actions of xenon and isoflurane.
Topics: Angiography; Animals; Biomarkers; Disease Models, Animal; Heart Ventricles; Hemodynamics; Isoflurane | 2008 |
A modified suture technique produces consistent cerebral infarction in rats.
Topics: Analysis of Variance; Anesthetics; Animals; Brain Ischemia; Cerebrovascular Circulation; Disease Mod | 2008 |
Progression and variability of TNBS colitis-associated inflammation in rats assessed by contrast-enhanced and T2-weighted MRI.
Topics: Anesthetics, Inhalation; Animals; Colitis; Colon; Contrast Media; Disease Models, Animal; Disease Pr | 2009 |
Effects of isoflurane on hippocampal seizures at immature rats in vivo.
Topics: Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Anticonvulsants; Disease Models, An | 2008 |
Does the choice of the halogenated anesthetic influence renal function during hemorrhagic shock and resuscitation?
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Cardiac Output; Creatinine; Disease Models, Animal | 2009 |
Effects of emulsified isoflurane on haemodynamics and cardiomyocyte apoptosis in rats with myocardial ischaemia.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Cardiotonic Agents; Caspase 3; Disea | 2009 |
Isoflurane suppresses stress-enhanced fear learning in a rodent model of post-traumatic stress disorder.
Topics: Animals; Disease Models, Animal; Fear; Isoflurane; Learning; Male; Rats; Rats, Long-Evans; Stress Di | 2009 |
Y-27632 augments the isoflurane-induced relaxation of bronchial smooth muscle in rats.
Topics: Acetylcholine; Amides; Anesthetics, Inhalation; Animals; Asthma; Bronchi; Disease Models, Animal; Do | 2008 |
Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia.
Topics: Alzheimer Disease; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Calcium-Calmodulin-Depe | 2009 |
Comparison of systemic Listeria monocytogenes infection in esophageally inoculated mice anesthetized with isoflurane or pentobarbital.
Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Animals; Disease Models, Animal; Isoflurane; Listeri | 2009 |
Early administration of xenon or isoflurane may not improve functional outcome and cerebral alterations in a porcine model of cardiac arrest.
Topics: Anesthetics, Inhalation; Animals; Brain; Cardiopulmonary Resuscitation; Disease Models, Animal; Drug | 2009 |
Ketamine anaesthesia interferes with the quinolinic acid-induced lesion in a rat model of Huntington's disease.
Topics: Anesthetics, Inhalation; Animals; Antiparkinson Agents; Apomorphine; Brain; Disease Models, Animal; | 2009 |
Effects of deep sedation or general anesthesia on cardiac function in mice undergoing cardiovascular magnetic resonance.
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Body Temperature; Conscious Sedation; Deep Se | 2009 |
Time course of desflurane-induced preconditioning in rabbits.
Topics: Anesthetics, Inhalation; Animals; Arginine; Desflurane; Disease Models, Animal; Ischemic Preconditio | 2010 |
The role of nitric oxide in the development of neurogenic pulmonary edema in spinal cord-injured rats: the effect of preventive interventions.
Topics: Anesthetics, Inhalation; Animals; Atropine; Baroreflex; Blood Pressure; Bradycardia; Disease Models, | 2009 |
Isoflurane preconditioning ameliorates endotoxin-induced acute lung injury and mortality in rats.
Topics: Acid-Base Equilibrium; Acute Lung Injury; Animals; Cytoprotection; Disease Models, Animal; Endotoxem | 2009 |
The acute hypoxic ventilatory response under halothane, isoflurane, and sevoflurane anaesthesia in rats.
Topics: Anesthetics, Inhalation; Animals; Carbon Dioxide; Disease Models, Animal; Dose-Response Relationship | 2010 |
Murine pulmonary inflammation model: a comparative study of anesthesia and instillation methods.
Topics: Acute Disease; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Biomarkers; Bronchoalveolar | 2010 |
Cardioprotection afforded by St Thomas solution is enhanced by emulsified isoflurane in an isolated heart ischemia reperfusion injury model in rats.
Topics: Anesthetics, Inhalation; Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Creatine K | 2010 |
A mouse model of severe halothane hepatitis based on human risk factors.
Topics: Age Factors; Anesthetics, Inhalation; Animals; Blotting, Western; Chemical and Drug Induced Liver In | 2010 |
Amygdala transcriptome and cellular mechanisms underlying stress-enhanced fear learning in a rat model of posttraumatic stress disorder.
Topics: Amygdala; Anesthetics, Inhalation; Animals; Astrocytes; Brain Chemistry; Disease Models, Animal; Ele | 2010 |
Housing environment influences the need for pain relief during post-operative recovery in mice.
Topics: Analgesics, Non-Narcotic; Anesthetics, Inhalation; Animals; Behavior, Animal; Body Weight; Disease M | 2010 |
Dopamine neuron stimulating actions of a GDNF propeptide.
Topics: Animals; Apomorphine; Disease Models, Animal; Dopamine; Glial Cell Line-Derived Neurotrophic Factor; | 2010 |
Anesthesia with isoflurane increases amyloid pathology in mice models of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Anesthesia, General; Anesthetics, Inhalation; Animals; Apo | 2010 |
Cyclosporine does not reduce myocardial infarct size in a porcine ischemia-reperfusion model.
Topics: Anesthetics; Animals; Apoptosis Inducing Factor; Caspase 3; Cyclosporine; Disease Models, Animal; Dr | 2010 |
Isoflurane preconditioning induces neuroprotection by attenuating ubiquitin-conjugated protein aggregation in a mouse model of transient global cerebral ischemia.
Topics: Animals; Apoptosis; Blotting, Western; CA1 Region, Hippocampal; Cell Survival; Cerebrovascular Circu | 2010 |
Evaluation of the anti-inflammatory effects of ellagic acid.
Topics: Anesthetics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; | 2010 |
Multi-limb acquisition of motor evoked potentials and its application in spinal cord injury.
Topics: Analgesics; Animals; Biophysics; Disease Models, Animal; Electric Stimulation; Evoked Potentials, Mo | 2010 |
Emulsified isoflurane preconditioning protects against liver and lung injury in rat model of hemorrhagic shock.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Disease Models, A | 2011 |
Role of the autonomic nervous system in cardioprotection by remote preconditioning in isoflurane-anaesthetized dogs.
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Autonomic Denervation; Autonomic Nervous Syst | 2011 |
Effects of intrathecal isoflurane administration on nociception and Fos expression in the rat spinal cord.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Exp | 2011 |
Effects of methylene blue and volatile anesthetics on survival in a murine hemorrhage resuscitation model.
Topics: Analysis of Variance; Animals; Chi-Square Distribution; Disease Models, Animal; Fluid Therapy; Halot | 2010 |
Spatial memory using active allothetic place avoidance in adult rats after isoflurane anesthesia: a potential model for postoperative cognitive dysfunction.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Avoidance Learning; Cognition Disorders; D | 2011 |
A non-invasive intranasal inoculation technique using isoflurane anesthesia to infect the brain of mice with rabies virus.
Topics: Anesthetics, Inhalation; Animals; Brain; Disease Models, Animal; Isoflurane; Mice; Rabies; Survival | 2011 |
Effect of general anesthetics on IOP in elevated IOP mouse model.
Topics: Anesthesia, General; Anesthetics, Combined; Anesthetics, General; Animals; Behavior, Animal; Disease | 2011 |
Severity of locomotor and cardiovascular derangements after experimental high-thoracic spinal cord injury is anesthesia dependent in rats.
Topics: Anesthetics; Animals; Blood Pressure; Cardiovascular System; Disease Models, Animal; Female; Heart R | 2012 |
Spinal anesthesia in infant rats: development of a model and assessment of neurologic outcomes.
Topics: Anesthesia, Spinal; Animals; Animals, Newborn; Blood Gas Analysis; Bupivacaine; Disease Models, Anim | 2011 |
Pre-treatment with isoflurane ameliorates renal ischemic-reperfusion injury in mice.
Topics: Animals; Apoptosis; Blotting, Western; Creatinine; Disease Models, Animal; Erythropoietin; Hypoxia-I | 2011 |
Isoflurane preconditioning affords functional neuroprotection in a murine model of intracerebral hemorrhage.
Topics: Albumins; Anesthetics, Inhalation; Animals; Brain; Brain Edema; Cerebral Hemorrhage; Disease Models, | 2011 |
Anesthesia in presymptomatic Alzheimer's disease: a study using the triple-transgenic mouse model.
Topics: Alzheimer Disease; Anesthetics, Inhalation; Animals; Brain; Cognition Disorders; Disease Models, Ani | 2011 |
Erythropoietin attenuates isoflurane-induced neurodegeneration and learning deficits in the developing mouse brain.
Topics: Air; Analysis of Variance; Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Brain; Dis | 2011 |
Isoflurane induces hippocampal cell injury and cognitive impairments in adult rats.
Topics: Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Caspase 3; Cognition Disorders; Conditionin | 2011 |
The effect of blood pressure (37 vs 45 mmHg) and carotid occlusion duration (8 vs 10 min) on CA1-4 neuronal damage when using isoflurane in a global cerebral ischemia rat model.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Carotid Arteries; Cell Survival; Disease Models, A | 2011 |
Interactions between nitrous oxide and tissue plasminogen activator in a rat model of thromboembolic stroke.
Topics: Animals; Binding Sites; Brain; Disease Models, Animal; Isoflurane; Male; N-Methylaspartate; Neuropro | 2011 |
Hypoxia inducible factor-1α is involved in the neurodegeneration induced by isoflurane in the brain of neonatal rats.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Brain; Calcium; Cell Survival; Cells, | 2012 |
Simple model of forebrain ischemia in mouse.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Disea | 2012 |
Determination of minimum alveolar concentration for isoflurane and sevoflurane in a rodent model of human metabolic syndrome.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Behavior, Animal; Disease Models, Anim | 2012 |
Trehalose protects from aggravation of amyloid pathology induced by isoflurane anesthesia in APP(swe) mutant mice.
Topics: Alzheimer Disease; Anesthetics, Inhalation; Animals; Disease Models, Animal; Female; Humans; Isoflur | 2012 |
Desflurane-induced post-conditioning against myocardial infarction is mediated by calcium-activated potassium channels: role of the mitochondrial permeability transition pore.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Desflurane; Disease Models, Animal; Ischemic | 2012 |
Isoflurane anesthesia precipitates tauopathy and upper airways dysfunction in pre-symptomatic Tau.P301L mice: possible implication for neurodegenerative diseases.
Topics: Alzheimer Disease; Anesthetics, Inhalation; Animals; Brain Stem; Disease Models, Animal; Isoflurane; | 2012 |
Influence of isoflurane on neuronal death and outcome in a rat model of traumatic brain injury.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Brain Injuries; Disease Models, Animal; In Situ Nick-En | 2012 |
Surgical optimization and characterization of a minimally invasive aortic banding procedure to induce cardiac hypertrophy in mice.
Topics: Anesthesia, Inhalation; Animals; Aorta, Thoracic; Blood Pressure; Cardiomegaly; Disease Models, Anim | 2012 |
Volatile anesthetic preconditioning attenuated sepsis induced lung inflammation.
Topics: Anesthetics, Inhalation; Animals; Cecum; Disease Models, Animal; Intercellular Adhesion Molecule-1; | 2012 |
Dexmedetomidine prevents alterations of intestinal microcirculation that are induced by surgical stress and pain in a novel rat model.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Inhalation; Animals; Blood Flow Velocity; Blood P | 2012 |
Inflammatory immune responses in a reproducible mouse brain death model.
Topics: Anesthesia; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Blood Pressure; Brain De | 2012 |
The effects of anesthesia, mouse strain and age on intraocular pressure and an improved murine model of experimental glaucoma.
Topics: Acepromazine; Aging; Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Axons; | 2012 |
Isoflurane/nitrous oxide anesthesia and stress-induced procedures enhance neuroapoptosis in intrauterine growth-restricted piglets.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Brain; Disease | 2012 |
Three aspects are critical for carrying out intraportal islet transplants successfully in a diabetes mouse model.
Topics: Anesthetics, Inhalation; Animals; Diabetes Mellitus; Disease Models, Animal; Hemostasis, Surgical; I | 2012 |
Isoflurane blocks temporary tinnitus.
Topics: Acoustic Stimulation; Anesthetics, Inhalation; Animals; Behavior, Animal; Disease Models, Animal; Fe | 2012 |
Ischemia-reperfusion injury of the mouse kidney.
Topics: Anesthetics, General; Animals; Disease Models, Animal; Female; Hypnotics and Sedatives; Isoflurane; | 2012 |
Caffeic acid phenethyl ester effects in the kidney during ischemia and reperfusion in rats anesthetized with isoflurane.
Topics: Anesthetics, Inhalation; Animals; Biomarkers; Caffeic Acids; Creatinine; Disease Models, Animal; Iso | 2012 |
Influence of progressive hemorrhage and subsequent cardiopulmonary resuscitation on the bispectral index during isoflurane anesthesia in a swine model.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Animals; Cardiopulmonary Resuscitation; Cerebrov | 2012 |
Comparison between adenosine and isoflurane for assessing the coronary flow reserve in mouse models of left ventricular pressure and volume overload.
Topics: Adenosine; Animals; Coronary Circulation; Disease Models, Animal; Echocardiography, Doppler; Feasibi | 2012 |
The effects of anesthetic regimen in 90% hepatectomy in rats.
Topics: Anesthesia; Anesthetics; Anesthetics, Inhalation; Animals; Blood Glucose; Disease Models, Animal; Gl | 2012 |
Isoflurane exposure during mid-adulthood attenuates age-related spatial memory impairment in APP/PS1 transgenic mice.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Anesthetics, Inhalation; Animals; Di | 2012 |
Pneumonectomy in isoflurane-anesthetized rats without tracheal intubation: an experimental model.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Contraindicati | 2014 |
Minocycline mitigates isoflurane-induced cognitive impairment in aged rats.
Topics: Aging; Anesthetics, Inhalation; Animals; bcl-2-Associated X Protein; Caspase 3; Cells, Cultured; Cog | 2013 |
Effects of isoflurane-induced anaesthesia on cognitive performance in a mouse model of Alzheimer's disease: A randomised trial in transgenic APP23 mice.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Anesthetics, Inhalation; Animals; Be | 2013 |
Propofol administration to the fetal-maternal unit reduces cardiac injury in late-preterm lambs subjected to severe prenatal asphyxia and cardiac arrest.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Animals, Newborn; Asphyxia Neonatorum; B | 2013 |
Xenon and isoflurane reduce left ventricular remodeling after myocardial infarction in the rat.
Topics: Anesthetics, Inhalation; Animals; Cardiotonic Agents; Disease Models, Animal; Electrocardiography; I | 2013 |
Effects of different anesthetics in the murine model of EHV-1 infection.
Topics: Analysis of Variance; Anesthetics; Animals; Cell Death; Cell Proliferation; Disease Models, Animal; | 2013 |
Desflurane improves neurologic outcome after low-flow cardiopulmonary bypass in newborn pigs.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cardiopulmonary Bypass; Desflurane; Disease Mode | 2002 |
Isoflurane preconditioning reduces purkinje cell death in an in vitro model of rat cerebellar ischemia.
Topics: Amino Acid Transport System X-AG; Anesthetics, Inhalation; Animals; Aspartic Acid; Brain Ischemia; C | 2003 |
Effects of isoflurane on the auditory brainstem responses and middle latency responses of rats.
Topics: Animals; Auditory Pathways; Auditory Threshold; Differential Threshold; Disease Models, Animal; Evok | 2003 |
Comparison of adenosine, isoflurane, and desflurane on myocardial tissue oxygen pressure during coronary artery constriction in dogs.
Topics: Adenosine; Animals; Blood Pressure; Carbon Dioxide; Constriction, Pathologic; Coronary Circulation; | 2003 |
Effects of pressure- and volume-controlled inverse ratio ventilation on haemodynamic variables, intracranial pressure and cerebral perfusion pressure in rabbits: a model of subarachnoid haemorrhage under isoflurane anaesthesia.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Female; Hemodynamics; Intracranial Pressur | 2003 |
Comparison of isoflurane and propofol-fentanyl anaesthesia in a swine model of asphyxia.
Topics: Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Asphyxia; Blood P | 2003 |
Influence of isoflurane on left atrial function in dogs with pacing-induced cardiomyopathy: evaluation with pressure-volume relationships.
Topics: Anesthetics, Inhalation; Animals; Atrial Function, Left; Blood Pressure; Cardiac Pacing, Artificial; | 2003 |
Effects of dopamine transporter inhibitors on cocaine self-administration in rhesus monkeys: relationship to transporter occupancy determined by positron emission tomography neuroimaging.
Topics: Anesthesia; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Plasma Mem | 2004 |
Desflurane results in higher cerebral blood flow than sevoflurane or isoflurane at hypocapnia in pigs.
Topics: Anesthetics, Inhalation; Animals; Blood Flow Velocity; Blood Pressure; Cerebrovascular Circulation; | 2004 |
Isoflurane preconditioning induces neuroprotection against ischemia via activation of P38 mitogen-activated protein kinases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Disease Models, Animal; Imidazoles | 2004 |
Anesthesia and acoustic stress-induced intra-uterine growth retardation in mice.
Topics: Acoustics; Anesthesia; Anesthetics, Inhalation; Animals; Bone Development; Disease Models, Animal; F | 2004 |
Isoflurane applied during ischemia enhances intracellular calcium accumulation in ventricular myocytes in part by reactive oxygen species.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Calcium; Disease Models, Animal; Fluorescent | 2004 |
A rabbit model for evaluation of surgical anesthesia and analgesia: characterization and validation with isoflurane anesthesia and fentanyl analgesia.
Topics: Analgesia; Analgesics, Opioid; Anesthesia; Anesthetics, Inhalation; Animals; Disease Models, Animal; | 2004 |
Isoflurane preserves central nervous system blood flow during intraoperative cardiac tamponade in dogs.
Topics: Analgesics; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cardiac Tamponade; Central N | 2004 |
Continuous arterial spin labeling using a train of adiabatic inversion pulses.
Topics: Anesthetics, Inhalation; Animals; Brain; Brain Neoplasms; Carbon Dioxide; Cerebrovascular Circulatio | 2005 |
Modern anesthesia and peroperative monitoring methods reduce per- and postoperative mortality during transient occlusion of the middle cerebral artery in rats.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Disease Models, Animal; Female; Infarction | 2005 |
Opposing effects of isoflurane and sevoflurane on neurogenic pulmonary edema development in an animal model.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Isoflurane; Male; Methyl Et | 2005 |
Description and technical pitfalls of a hepatoma model and of intra-arterial injection of radiolabelled lipiodol in the rat.
Topics: Anesthetics; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Female; I | 2005 |
A brief exposure to isoflurane (50 s) significantly impacts on plasma cytokine levels in endotoxemic rats.
Topics: Anesthetics, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Chemokine CCL5; Disease Models, Anim | 2005 |
In vivo assessment of myocardial blood flow in rat heart using magnetic resonance imaging: effect of anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Coronary Circulation; Disease Models, Anim | 2005 |
Isoflurane preconditioning protects motor neurons from spinal cord ischemia: its dose-response effects and activation of mitochondrial adenosine triphosphate-dependent potassium channel.
Topics: Anesthetics, Inhalation; Animals; Anterior Horn Cells; Cell Death; Cell Survival; Disease Models, An | 2005 |
Effects of sevoflurane and desflurane in CA1 after incomplete cerebral ischemia in rats.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Biopsy, Needle; Brain Ischemia; Cerebrovascu | 2005 |
The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Anesthetics, Inhalati | 2005 |
Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse.
Topics: Anesthesia; Anesthetics; Animals; Caffeine; Calcium; Disease Models, Animal; Hot Temperature; Isoflu | 2006 |
Protective effect of isoflurane anesthesia on noise-induced hearing loss in mice.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Cell Survival; Disease Models, Animal; Evo | 2005 |
Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats.
Topics: Anesthetics; Animals; Brain; Brain Injuries; Cell Survival; Cognition Disorders; Diazepam; Disease M | 2006 |
Reeler mutant mice exhibit seizures during recovery from isoflurane-induced anesthesia.
Topics: Anesthetics, Inhalation; Animals; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Female; | 2006 |
General anesthesia delays the inflammatory response and increases survival for mice with endotoxic shock.
Topics: Anesthesia, General; Anesthetics, General; Animals; Cytokines; Disease Models, Animal; Inflammation; | 2006 |
Isoflurane exerts neuroprotective actions at or near the time of severe traumatic brain injury.
Topics: Anesthetics, Intravenous; Animals; Behavior, Animal; Blood Pressure; Brain Injuries; Cell Count; Dis | 2006 |
Epidural anaesthesia restores pancreatic microcirculation and decreases the severity of acute pancreatitis.
Topics: Acute Disease; Anesthesia, Epidural; Animals; Disease Models, Animal; Hindlimb; Isoflurane; Male; Mi | 2006 |
Epidural anaesthesia restores pancreatic microcirculation and decreases the severity of acute pancreatitis.
Topics: Acute Disease; Anesthesia, Epidural; Animals; Disease Models, Animal; Hindlimb; Isoflurane; Male; Mi | 2006 |
Epidural anaesthesia restores pancreatic microcirculation and decreases the severity of acute pancreatitis.
Topics: Acute Disease; Anesthesia, Epidural; Animals; Disease Models, Animal; Hindlimb; Isoflurane; Male; Mi | 2006 |
Epidural anaesthesia restores pancreatic microcirculation and decreases the severity of acute pancreatitis.
Topics: Acute Disease; Anesthesia, Epidural; Animals; Disease Models, Animal; Hindlimb; Isoflurane; Male; Mi | 2006 |
Intraocular pressure measurement in mice: a comparison between Goldmann and rebound tonometry.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Intraocular Pressure; Isoflurane; Laser Co | 2007 |
The characteristics of intravenous adenosine-induced antinociception in a rabbit model of acute nociceptive pain: a comparative study with remifentanil.
Topics: Adenosine; Analgesics; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Blood Pressure; Carbon | 2006 |
Effects of altered consciousness on the protective glottic closure reflex.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Deglutition; Disease Models, Animal; Elect | 2006 |
Cardiac electrophysiologic interactions of bepridil, a new calcium antagonist, with enflurane, halothane, and isoflurane.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Bepridil; Calcium Channel Blockers; Chlo | 1988 |
Isoflurane improves survival and protects against renal and hepatic injury in murine septic peritonitis.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Isoflurane; Kidney; Liver; Male; Mice; Mic | 2007 |
Comparison of propofol and isoflurane anesthesia in orthotopic pig-to-baboon cardiac xenotransplantation.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Pressure; Cen | 2007 |
A new model of severe neurogenic pulmonary edema in spinal cord injured rat.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Isoflura | 2007 |
Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics.
Topics: Acetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Anesthetics, Inha | 2007 |
[Protective effect of heat-shock protein 27 on myocardium with isoflurane preconditioning in myocardial ischemia/reperfusion injury of myocardium in rabbit].
Topics: Animals; Disease Models, Animal; HSP27 Heat-Shock Proteins; Ischemic Preconditioning, Myocardial; Is | 2007 |
A flow sensitive alternating inversion recovery (FAIR)-MRI protocol to measure hemispheric cerebral blood flow in a mouse stroke model.
Topics: Anesthetics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Autoradiography; Blood Ci | 2008 |
The influence of hemorrhagic shock on the minimum alveolar anesthetic concentration of isoflurane in a swine model.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Isoflurane; Pulmonary Alveoli; Shock, Hemo | 2007 |
[Protection of liver against ischemia/reperfusion injury by Kupffer cell mediated emulsified isoflurane preconditioning: experiment with rats].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Disease Models, Animal; Emulsions; Injec | 2007 |
Alpha-chloralose is a suitable anesthetic for chronic focal cerebral ischemia studies in the rat: a comparative study.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Brain; Brain Injuries; Brain Ischemia; Cerebrovascula | 2008 |
Preconditioning by isoflurane retains its protection against ischemia-reperfusion injury in postinfarct remodeled rat hearts.
Topics: Anesthetics, Inhalation; Animals; Cardiotonic Agents; Chromones; Coronary Vessels; Decanoic Acids; D | 2008 |
Cardiac remodelling hinders activation of cyclooxygenase-2, diminishing protection by delayed pharmacological preconditioning: role of HIF1 alpha and CREB.
Topics: Active Transport, Cell Nucleus; Animals; Blotting, Western; Cardiovascular Agents; Colorimetry; Cycl | 2008 |
Delayed tolerance with repetitive transient focal ischemic preconditioning in the mouse.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Brain; Cell Survival; Cerebral Cortex; Corpus Striatum | 2008 |
Hepatic energy metabolism and the differential protective effects of sevoflurane and isoflurane anesthesia in a rat hepatic ischemia-reperfusion injury model.
Topics: Adenosine Triphosphate; Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotrans | 2008 |
Anesthetics and natural heme oxygenase-1 inducers: waiting for carbon monoxide?
Topics: Anesthetics; Animals; Anthocyanins; Antioxidants; Carbon Monoxide; Curcumin; Cytoprotection; Disease | 2008 |
Isoflurane attenuates myoglobin release during ischemic and/or reperfusion periods.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Heart R | 2008 |
Emulsified intravenous versus evaporated inhaled isoflurane for heart protection: old wine in a new bottle or true innovation?
Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Chemistry, Pharmaceutical; Coronary Ve | 2008 |
Emulsified isoflurane produces cardiac protection after ischemia-reperfusion injury in rabbits.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Coronary Vessels; Creatine Kinase; Cyt | 2008 |
Effects of anemia and hypotension on porcine optic nerve blood flow and oxygen delivery.
Topics: Anemia; Animals; Blood Flow Velocity; Cerebrovascular Circulation; Disease Models, Animal; Hypotensi | 2008 |
[Isoflurane pretreatment reduced liver injury induced by ischemia/reperfusion combined with lipopolysaccharide in rats].
Topics: Alanine Transaminase; Animals; Disease Models, Animal; Isoflurane; Lipopolysaccharides; Liver; Male; | 2008 |
The effects of chrysin, a Passiflora incarnata extract, on natural killer cell activity in male Sprague-Dawley rats undergoing abdominal surgery.
Topics: Administration, Inhalation; Analysis of Variance; Anesthetics, Inhalation; Animals; Dimethyl Sulfoxi | 2008 |
Sepsis reduces isoflurane MAC in a normotensive animal model of sepsis.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Disease Models, Animal; Isoflurane; Male; Pulmonar | 1995 |
Regional myocardial function during contiguous ischaemia in an anaesthetized canine model: comparison of six methods of measurement.
Topics: Animals; Disease Models, Animal; Dogs; Dopamine; Epinephrine; Female; Halothane; Heart; Heart Functi | 1994 |
Actions of halothane and isoflurane on Purkinje fibers in the infarcted canine heart: conduction, regional refractoriness, and reentry.
Topics: Animals; Disease Models, Animal; Dogs; Electric Stimulation; Electrophysiology; Halothane; Heart Con | 1993 |
Pulmonary venodilation by isoflurane improves gas exchange during Escherichia coli bacteremia.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Bacteremia; Blood Gas Analysis; Disease M | 1993 |
Pharmacologically induced heart failure for the evaluation of circulatory assistance.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Cattle; | 1996 |
A method for long duration anaesthesia for a new hindlimb ischaemia-reperfusion model in mice.
Topics: Analgesics, Opioid; Anesthesia; Anesthetics, Inhalation; Animals; Body Temperature; Buprenorphine; D | 1997 |
Anesthetic regimen effects on a pediatric porcine model of asphyxial arrest.
Topics: Adjuvants, Anesthesia; Anesthesia, General; Anesthetics, Combined; Anesthetics, Dissociative; Anesth | 1997 |
Energy status in anoxic rat hepatocytes: effects of isoflurane, solution composition, and hypothermia.
Topics: Adenine Nucleotides; Adenosine; Allopurinol; Anesthetics, Inhalation; Animals; Cell Hypoxia; Chromat | 1995 |
The effects of isoflurane and halothane on left ventricular afterload in dogs with dilated cardiomyopathy.
Topics: Anesthetics, Inhalation; Animals; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Disease Model | 1997 |
Augmented neuronal death in CA3 hippocampus following hyperventilation early after controlled cortical impact.
Topics: Anesthetics, Inhalation; Animals; Blood Glucose; Blood Pressure; Body Temperature; Brain Concussion; | 1998 |
Early and late post-ischaemic recovery of contractile function is affected to different degrees by isoflurane and halothane in the anaesthetized rabbit model.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Female; Halothane; Hemodynamics; Isofluran | 1998 |
[Acidosis and neuroprotection in two types of acidosis model rats under isoflurane anesthesia: evaluation of blood flow, pH and amino acid levels in the cortex].
Topics: Acidosis; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Cerebral Cortex; Disease Models, | 1998 |
Core and penumbral nitric oxide synthase activity during cerebral ischemia and reperfusion in the rat pup.
Topics: Animals; Brain; Brain Ischemia; Disease Models, Animal; Isoflurane; Male; Nitric Oxide Synthase; Rat | 1999 |
[Depressive effects of propofol on apoptotic injury and delayed neuronal death after forebrain ischemia in the rat--comparison with nitrous oxide-oxygen-isoflurane].
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2000 |
Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole.
Topics: Acute Disease; Anesthesia; Anesthetics, Inhalation; Animals; Astemizole; Atrioventricular Node; Cath | 2001 |
Influence of sepsis on minimum alveolar concentration of desflurane in a porcine model.
Topics: Anesthetics, Inhalation; Animals; Bacteremia; Desflurane; Disease Models, Animal; Hemodynamics; Isof | 2001 |
Propofol versus isoflurane anesthesia under hypothermic conditions: effects on intracranial pressure and local cerebral blood flow after diffuse traumatic brain injury in the rat.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Blood Pressure; Body | 2001 |
Torsade de pointes and sudden death induced by thiopental and isoflurane anesthesia in dogs with cardiac electrical remodeling.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Death, Sudden, Cardiac; Disease Models, | 2002 |
Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent.
Topics: Anesthetics, Inhalation; Animals; Body Temperature; Brain; Brain Infarction; Brain Ischemia; Cells, | 2002 |
Administration of the anesthetic isoflurane to mice: a model for acute intermittent porphyria?
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Glucose; Isofl | 1992 |
Dose-response relationship of isoflurane and halothane versus coronary perfusion pressures. Effects on flow redistribution in a collateralized chronic swine model.
Topics: Animals; Blood Pressure; Collateral Circulation; Contraindications; Coronary Circulation; Coronary D | 1992 |
Alterations in collateral blood flow produced by isoflurane in a chronically instrumented canine model of multivessel coronary artery disease.
Topics: Adenosine; Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Disease Models, | 1991 |
Dose-related effects of isoflurane associated with low plasma concentrations of verapamil on global and regional function in normal and compromised canine myocardium.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Dose- | 1991 |
The effect of pentobarbital and isoflurane on glucose metabolism in thermally injured rat brain.
Topics: Animals; Autoradiography; Brain Injuries; Disease Models, Animal; Freezing; Glucose; Isoflurane; Mal | 1990 |
Arterial to end-tidal CO2 tension and alveolar dead space in halothane- or isoflurane-anesthetized ponies.
Topics: Anesthesia, General; Animals; Carbon Dioxide; Disease Models, Animal; Fractures, Bone; Halothane; Ho | 1985 |
Guinea-pig model of halothane-associated hepatotoxicity in the absence of enzyme induction and hypoxia.
Topics: Animals; Biotransformation; Blood Gas Analysis; Chemical and Drug Induced Liver Injury; Disease Mode | 1985 |