isoflurane has been researched along with Delirium of Mixed Origin in 18 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
| Excerpt | Relevance | Reference |
|---|---|---|
| " One patient in the propofol group developed delirium compared to zero in desflurane." | 9.24 | The effect of desflurane versus propofol anesthesia on postoperative delirium in elderly obese patients undergoing total knee replacement: A randomized, controlled, double-blinded clinical trial. ( Goodman, S; Huddleston, J; Lemmens, HJ; Maloney, W; Sommer, BR; Tanaka, P, 2017) |
| "Desflurane and sevoflurane are associated with postoperative emergence delirium (ED) in children." | 9.17 | Postoperative emergence delirium in pediatric patients undergoing cataract surgery--a comparison of desflurane and sevoflurane. ( Ghai, B; Ram, J; Sethi, S; Wig, J, 2013) |
| "This randomized control trial was designed to evaluate the incidence of emergence delirium (ED) in preschool children receiving sevoflurane or desflurane anesthesia combined with an effective caudal block." | 9.17 | Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale. ( Benigni, A; Busi, I; Di Marco, S; Emre, S; Frawley, G; Ingelmo, PM; Locatelli, BG; Meroni, V; Minardi, C; Sonzogni, V; Spotti, A, 2013) |
| "Incidence of emergence delirium in sevoflurane group was 11." | 9.16 | Recovery profile and emergence delirium following sevoflurane and isoflurane anesthesia in children posted for cleft lip surgery. ( Jindal, P; Khurana, G; Oberoi, D; Sharma, JP, 2012) |
| "Desflurane anesthesia is same as sevoflurane regarding perioperative delirium in elderly patients." | 7.81 | [Effects of Sevoflurane or Desflurane Anesthesia on Perioperative Delirium in Elderly Patients Undergoing Surgical Repair of Hip Fracture]. ( Hiro, K; Kurata, M; Oi, Y; Okuda, M; Omoto, T; Sugiyama, T, 2015) |
| "The demonstration that isoflurane contributes to well-described mechanisms of Alzheimer's neuropathogenesis provides a plausible link between the acute effects of anesthesia, a well-described risk factor for delirium, and the more long-term sequelae of dementia." | 7.73 | Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia. ( Crosby, G; Culley, DJ; Dong, Y; Inouye, SK; Maeda, U; Moir, R; Tanzi, RE; Xie, Z, 2006) |
| "Emergence delirium is a common problem in children recovering from general anaesthesia." | 6.82 | A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children. ( Bala, I; Bhatia, N; Dwivedi, D; Makkar, JK; Singh, PM, 2016) |
| " One patient in the propofol group developed delirium compared to zero in desflurane." | 5.24 | The effect of desflurane versus propofol anesthesia on postoperative delirium in elderly obese patients undergoing total knee replacement: A randomized, controlled, double-blinded clinical trial. ( Goodman, S; Huddleston, J; Lemmens, HJ; Maloney, W; Sommer, BR; Tanaka, P, 2017) |
| "Desflurane and sevoflurane are associated with postoperative emergence delirium (ED) in children." | 5.17 | Postoperative emergence delirium in pediatric patients undergoing cataract surgery--a comparison of desflurane and sevoflurane. ( Ghai, B; Ram, J; Sethi, S; Wig, J, 2013) |
| "This randomized control trial was designed to evaluate the incidence of emergence delirium (ED) in preschool children receiving sevoflurane or desflurane anesthesia combined with an effective caudal block." | 5.17 | Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale. ( Benigni, A; Busi, I; Di Marco, S; Emre, S; Frawley, G; Ingelmo, PM; Locatelli, BG; Meroni, V; Minardi, C; Sonzogni, V; Spotti, A, 2013) |
| "Incidence of emergence delirium in sevoflurane group was 11." | 5.16 | Recovery profile and emergence delirium following sevoflurane and isoflurane anesthesia in children posted for cleft lip surgery. ( Jindal, P; Khurana, G; Oberoi, D; Sharma, JP, 2012) |
| "We are uncertain whether maintenance with propofol-based TIVA or with inhalational agents affect incidences of postoperative delirium, mortality, or length of hospital stay because certainty of the evidence was very low." | 4.98 | Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery. ( Alderson, P; Lewis, SR; Miller, D; Pritchard, MW; Schofield-Robinson, OJ; Shelton, CL; Smith, AF, 2018) |
| "Desflurane anesthesia is same as sevoflurane regarding perioperative delirium in elderly patients." | 3.81 | [Effects of Sevoflurane or Desflurane Anesthesia on Perioperative Delirium in Elderly Patients Undergoing Surgical Repair of Hip Fracture]. ( Hiro, K; Kurata, M; Oi, Y; Okuda, M; Omoto, T; Sugiyama, T, 2015) |
| "The demonstration that isoflurane contributes to well-described mechanisms of Alzheimer's neuropathogenesis provides a plausible link between the acute effects of anesthesia, a well-described risk factor for delirium, and the more long-term sequelae of dementia." | 3.73 | Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia. ( Crosby, G; Culley, DJ; Dong, Y; Inouye, SK; Maeda, U; Moir, R; Tanzi, RE; Xie, Z, 2006) |
| "Emergence delirium is a common problem in children recovering from general anaesthesia." | 2.82 | A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children. ( Bala, I; Bhatia, N; Dwivedi, D; Makkar, JK; Singh, PM, 2016) |
| "Emergency delirium was common in both groups (32% overall: 40% for Group I, 25% for Group S)." | 2.69 | Tracheal extubation of deeply anesthetized pediatric patients: a comparison of isoflurane and sevoflurane. ( Bailey, AG; Calhoun, P; Freid, EB; Georges, LS; Kopp, VJ; Ramza, JT; Valley, RD, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 12 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanaka, P | 1 |
| Goodman, S | 1 |
| Sommer, BR | 1 |
| Maloney, W | 1 |
| Huddleston, J | 1 |
| Lemmens, HJ | 1 |
| Kawano, T | 1 |
| Yamanaka, D | 1 |
| Aoyama, B | 1 |
| Tateiwa, H | 1 |
| Shigematsu-Locatelli, M | 1 |
| Nishigaki, A | 1 |
| Iwata, H | 1 |
| Locatelli, FM | 1 |
| Yokoyama, M | 1 |
| Miller, D | 1 |
| Lewis, SR | 1 |
| Pritchard, MW | 1 |
| Schofield-Robinson, OJ | 1 |
| Shelton, CL | 1 |
| Alderson, P | 1 |
| Smith, AF | 1 |
| Sethi, S | 1 |
| Ghai, B | 1 |
| Ram, J | 1 |
| Wig, J | 1 |
| Lam, A | 1 |
| Davidson, A | 1 |
| Malarbi, S | 1 |
| Sheppard, S | 1 |
| Park, JH | 1 |
| Lim, BG | 1 |
| Lee, IO | 1 |
| Acharya, NK | 1 |
| Goldwaser, EL | 1 |
| Forsberg, MM | 1 |
| Godsey, GA | 1 |
| Johnson, CA | 1 |
| Sarkar, A | 1 |
| DeMarshall, C | 1 |
| Kosciuk, MC | 1 |
| Dash, JM | 1 |
| Hale, CP | 1 |
| Leonard, DM | 1 |
| Appelt, DM | 1 |
| Nagele, RG | 1 |
| Makkar, JK | 1 |
| Bhatia, N | 1 |
| Bala, I | 1 |
| Dwivedi, D | 1 |
| Singh, PM | 1 |
| Oi, Y | 1 |
| Omoto, T | 1 |
| Hiro, K | 1 |
| Sugiyama, T | 1 |
| Kurata, M | 1 |
| Okuda, M | 1 |
| Bilotta, F | 1 |
| Doronzio, A | 1 |
| Stazi, E | 1 |
| Titi, L | 1 |
| Zeppa, IO | 1 |
| Cianchi, A | 1 |
| Rosa, G | 1 |
| Paoloni, FP | 1 |
| Bergese, S | 1 |
| Asouhidou, I | 1 |
| Ioannou, P | 1 |
| Abramowicz, AE | 1 |
| Spinelli, A | 1 |
| Delphin, E | 1 |
| Ayrian, E | 1 |
| Zelman, V | 1 |
| Lumb, P | 1 |
| Locatelli, BG | 1 |
| Ingelmo, PM | 1 |
| Emre, S | 1 |
| Meroni, V | 1 |
| Minardi, C | 1 |
| Frawley, G | 1 |
| Benigni, A | 1 |
| Di Marco, S | 1 |
| Spotti, A | 1 |
| Busi, I | 1 |
| Sonzogni, V | 1 |
| Jindal, P | 1 |
| Khurana, G | 1 |
| Oberoi, D | 1 |
| Sharma, JP | 1 |
| Przybylo, HJ | 1 |
| Martini, DR | 1 |
| Mazurek, AJ | 1 |
| Bracey, E | 1 |
| Johnsen, L | 1 |
| Coté, CJ | 1 |
| Meyer, RR | 1 |
| Münster, P | 1 |
| Werner, C | 1 |
| Brambrink, AM | 1 |
| Xie, Z | 1 |
| Dong, Y | 1 |
| Maeda, U | 1 |
| Moir, R | 1 |
| Inouye, SK | 1 |
| Culley, DJ | 1 |
| Crosby, G | 1 |
| Tanzi, RE | 1 |
| Marsh, DF | 1 |
| Flynn, F | 1 |
| Lane, M | 1 |
| Morgan, P | 1 |
| Valley, RD | 1 |
| Ramza, JT | 1 |
| Calhoun, P | 1 |
| Freid, EB | 1 |
| Bailey, AG | 1 |
| Kopp, VJ | 1 |
| Georges, LS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparing the Efficacy Between Desflurane and Sevoflurane in Miantainance of Spontaneous General Anaesthesia Using Ambu Aura Gain in Paediatrics Patients[NCT04771962] | Phase 1/Phase 2 | 80 participants (Actual) | Interventional | 2020-01-01 | Completed | ||
| Effectivity of 0.5 mg/kg Propofol in the End of Anesthesia to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Inhalation Anesthesia[NCT03528954] | 54 participants (Actual) | Interventional | 2018-05-31 | Completed | |||
| The Effects of Operating Room Virtual Tour on Preoperative Anxiety, Emergence Delirium and Postoperative Behavioral Changes of Pediatric Patients: Prospective, Randomized, and Controlled Trial[NCT03172182] | 86 participants (Actual) | Interventional | 2017-08-01 | Completed | |||
| Post Operative Cognitive Recovery and Neuropsychological Complications After General Anesthesia. A Comparison Between Different Techniques of Anesthesia: A Multi-Center Observational Study[NCT00507195] | 1,200 participants (Anticipated) | Observational | 2007-05-31 | Recruiting | |||
| [NCT02909413] | 600 participants (Anticipated) | Interventional | 2016-10-31 | Not yet recruiting | |||
| Influence of Monitoring the Depth of General Anesthesia Upon the Incidence of PONV and Emergence Delirium in Children Undergoing Endoscopic Adenoidectomy in General Anesthesia[NCT04466579] | 100 participants (Actual) | Interventional | 2020-07-01 | Completed | |||
| Investigation of the DNA Methylation Profile in Children Who Presented Emergence Delirium[NCT03787849] | 175 participants (Actual) | Interventional | 2018-09-24 | Completed | |||
| A Prospective, Double-blind, Randomized Study to Investigate the Effect of Sugammadex vs. Neostigmine/Glycopyrrolate on Emergence Delirium During Sevoflurane-rocuronium Anesthesia in Pediatric Patients[NCT03229486] | Phase 4 | 40 participants (Actual) | Interventional | 2017-03-01 | Completed | ||
| Effect of Single Dose of Tramadol on Extubation Response and Quality of Emergence(Cough and Nausea Vomiting) Following Supratentorial Intracranial Surgery[NCT02964416] | Phase 4 | 80 participants (Actual) | Interventional | 2016-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Maximum Pediatric Anesthesia Emergence Delirium (PAED) score after arrival in the PACU.Higher values represent more emergence delirium (worse) PAED Score is represented with total PAED score summed up of subscales. The total score is reported and it ranges from 0 to 20. Higher score means worse state. (NCT03229486)
Timeframe: within 30 minutes after arrival at post-anesthesia care unit (PACU)
| Intervention | units on a scale (Median) |
|---|---|
| Sugammadex | 18 |
| Neostigmine | 18 |
Time from the start of administration of reversal agents to recovery of the TOF ratio to 0.7 (NCT03229486)
Timeframe: Time from the start of administration of reversal agents to recovery of the TOF ratio to 0.7, assessed up to 60 minutes
| Intervention | seconds (Mean) |
|---|---|
| Sugammadex | 72.7 |
| Neostigmine | 167.4 |
Time from the start of administration of reversal agents to recovery of the TOF ratio to 0.8 (NCT03229486)
Timeframe: Time from the start of administration of reversal agents to recovery of the TOF ratio to 0.8, assessed up to 60 minutes
| Intervention | seconds (Mean) |
|---|---|
| Sugammadex | 83.9 |
| Neostigmine | 213.6 |
Time from the start of administration of reversal agents to recovery of the TOF ratio to 0.9 (NCT03229486)
Timeframe: Time from the start of administration of reversal agents to recovery of the TOF ratio to 0.9, assessed up to 60 minutes
| Intervention | seconds (Mean) |
|---|---|
| Sugammadex | 99.6 |
| Neostigmine | 253.1 |
time from administration of reversal agent to time of eye opening or child showing purposeful movement (NCT03229486)
Timeframe: time from administration of reversal agent to time of eye opening or child showing purposeful movements, assessed up to 60 minutes
| Intervention | seconds (Mean) |
|---|---|
| Sugammadex | 275.8 |
| Neostigmine | 371.2 |
time from administration of reversal agent to time of tracheal extubation (NCT03229486)
Timeframe: time from administration of reversal agent to time of tracheal extubation, assessed up to 60 minutes
| Intervention | seconds (Mean) |
|---|---|
| Sugammadex | 312.1 |
| Neostigmine | 427.3 |
time from administration of reversal agent to time of deep, regular breathing (NCT03229486)
Timeframe: time from administration of reversal agent to time of deep, regular breathing, assessed up to 60 minutes
| Intervention | seconds (Mean) |
|---|---|
| Sugammadex | 273.8 |
| Neostigmine | 345.1 |
If there is any episode of bronchospasm or laryngospasm, it will be noted if it occured during emergence and for 6 hours post operatively. Absence of it will be considered as smooth emergence (NCT02964416)
Timeframe: at the time of extubation till 6 hours postoperatively
| Intervention | Number of Patients (Number) |
|---|---|
| Tramadol | 0 |
| Placebo | 0 |
Requirement of analgesia will be recorded at recovery room, 2, 4 and 6 hours postoperatively. If there is any need of analgesic, it will be noted and will be considered as one of the determinants of poor quality of emergence. (NCT02964416)
Timeframe: At Recovery room, 2, 4 and 6 hours postoperatively
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Recovery Room | 2h | 4h | 6h | |
| Placebo | 3 | 23 | 4 | 7 |
| Tramadol | 5 | 15 | 3 | 6 |
Convulsions will be recorded at Recovery Room, 2, 4 and 6 hours postoperatively.If there is any episode of convulsion, it will be noted. Absence of it will be considered as smooth emergence. (NCT02964416)
Timeframe: at Recovery Room, 2, 4 and 6 hours postoperatively
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Recovery Room | 2h | 4h | 6h | |
| Placebo | 0 | 0 | 0 | 0 |
| Tramadol | 0 | 0 | 1 | 0 |
"Post operative Glasgow Coma Scale (GCS) will be recorded at Recovery Room, 2, 4 and 6 hours postoperatively. If there is any deterioration in GCS less than 8/15, Patients will be intubated.~GCS categories <8 Low GCS 9-12 Intermediate GCS 13-15 Full GCS" (NCT02964416)
Timeframe: at Recovery Room, 2, 4 and 6 hours postoperatively
| Intervention | Number of Patients (Number) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Recovery Room : <8 | Recovery Room : 9-12 | Recovery Room : 13-15 | 2h : <8 | 2h : 9-12 | 2h : 13-15 | 4h : <8 | 4h : 9-12 | 4h : 13-15 | 6h : <8 | 6h : 9-12 | 6h : 13-15 | |
| Placebo | 0 | 0 | 41 | 0 | 1 | 40 | 1 | 0 | 40 | 1 | 0 | 40 |
| Tramadol | 0 | 1 | 38 | 0 | 1 | 38 | 0 | 0 | 39 | 0 | 0 | 39 |
Post operative nausea vomiting will be recorded at RR, 2, 4 and 6 hours postoperatively. If there is any episode of PONV it will be noted. Absence of it will be considered as smooth emergence (NCT02964416)
Timeframe: at Recovery Room , 2, 4 and 6 hours postoperatively
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Recovery Room | 2h | 4h | 6h | |
| Placebo | 0 | 3 | 1 | 1 |
| Tramadol | 0 | 3 | 0 | 0 |
Diastolic blood pressure will be recorded at 1 minute before giving the reversal (glycopyrolate and neostigmine) and then 1,2,5,10,20,30 minutes ,1,2,4 and 6 hours after extubation. If values of blood pressure rise more than 20% from baseline values injection Metoprolol 1mg (beta blocker) bolus will be used and titrated according to response. The study will end at 6 hours post extubation. (NCT02964416)
Timeframe: Diastolic BP from the time of extubation till 6 hours post operatively
| Intervention | mm Hg (Mean) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Base line | 1min Before Extubation | 1min After Extubation | 2 min | 5min | 10min | 20min | 30min | 1h | 2h | 4h | 6h | |
| Placebo | 77.83 | 78.65 | 85.78 | 82.41 | 78.59 | 78.32 | 76.73 | 76.93 | 75.33 | 75.89 | 78.00 | 74.89 |
| Tramadol | 75.92 | 77.30 | 83.97 | 79.19 | 78.68 | 77.37 | 78.19 | 77.14 | 76.39 | 75.71 | 74.85 | 75.26 |
Heart rate will be recorded at 1 minute before giving the reversal (glycopyrolate and neostigmine) and then 1,2,5,10,20,30 minutes ,1,2,4 and 6 hours after extubation. If haemodynamic values of heart rate rise more than 20% from baseline values injection Metoprolol 1mg (beta blocker) bolus will be used and titrated according to response. The study will end at 6 hours post extubation. (NCT02964416)
Timeframe: HR from the time of extubation till 6 hours post operatively
| Intervention | bpm (Mean) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | 1min Before Extubation | 1min After Extubation | 2 min | 5min | 10min | 20min | 30min | 1h | 2h | 4h | 6h | |
| Placebo | 79.37 | 91.41 | 98.54 | 93.50 | 90.00 | 86.70 | 83.38 | 84.10 | 82.46 | 81.97 | 81.23 | 78.20 |
| Tramadol | 82.26 | 89.30 | 93.61 | 89.61 | 86.27 | 86.26 | 82.44 | 81.92 | 79.53 | 80.03 | 78.94 | 79.65 |
Systolic blood pressure will be recorded at 1 minute before giving the reversal (glycopyrolate and neostigmine) and then 1,2,5,10,20,30 minutes ,1,2,4 and 6 hours after extubation. If values of blood pressure rise more than 20% from baseline values injection Metoprolol 1mg (beta blocker) bolus will be used and titrated according to response. The study will end at 6 hours post extubation. (NCT02964416)
Timeframe: Systolic BP from the time of extubation till 6 hours post operatively
| Intervention | mm Hg (Mean) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | 1min Before Extubation | 1min After Extubation | 2 min | 5min | 10min | 20min | 30min | 1h | 2h | 4h | 6h | |
| Placebo | 132.34 | 134.29 | 143.70 | 139.77 | 133.37 | 131.59 | 133.15 | 132.10 | 129.80 | 125.74 | 125.81 | 122.61 |
| Tramadol | 128.55 | 132.63 | 141.81 | 134.89 | 130.05 | 126.95 | 127.86 | 127.19 | 128.11 | 127.76 | 127.35 | 122.97 |
"If there is any episodes of denaturation (Oxygen saturation <92%), it will be noted it it is occurring during emergence.~Absence of it will be considered as smooth emergence" (NCT02964416)
Timeframe: at the time of extubation
| Intervention | Participants (Count of Participants) | ||||
|---|---|---|---|---|---|
| at resumption of spontaneous breathing | at the time of obeying of verbal commands | at the time of cuff deflation | at the time of extubation | 2 min after extubation | |
| Placebo | 0 | 0 | 0 | 0 | 0 |
| Tramadol | 0 | 0 | 0 | 0 | 0 |
"Cough will be described on following scale 5 = No coughing or straining, 4 = Very smooth minimal coughing, 3 = Moderate coughing, 2 = Marked coughing or straining,~1 = Poor extubation~Cough will be recorded on the above mentioned scale by resident/consultant at following time intervals of emergence~At resumption of spontaneous breathing,~Ability to respond to verbal commands~At cuff deflation~At extubation~2 minutes after extubation. It will be noted if it occurs during emergence at the above mentioned time intervals. Absence of it will be considered as smooth emergence." (NCT02964416)
Timeframe: Cough at the time of emergence
| Intervention | Participants (Count of Participants) | |||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| At resumption of spontaneous breathing72201515 | At resumption of spontaneous breathing72201516 | Ability to respond to verbal commands72201516 | Ability to respond to verbal commands72201515 | At cuff deflation72201516 | At cuff deflation72201515 | At extubation72201516 | At extubation72201515 | 2 minutes after extubation72201515 | 2 minutes after extubation72201516 | |||||||||||||||||||||||||||||||||||||||||
| Poor extubation | Marked coughing or straining | Moderate coughing | Very smooth minimal coughing | No coughing or straining | ||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 33 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 36 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 1 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 1 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 3 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 2 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 34 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 37 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 3 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 4 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 33 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 4 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 6 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 32 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 32 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 2 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 36 | |||||||||||||||||||||||||||||||||||||||||||||||||
1 review available for isoflurane and Delirium of Mixed Origin
| Article | Year |
|---|---|
Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave | 2018 |
9 trials available for isoflurane and Delirium of Mixed Origin
| Article | Year |
|---|---|
The effect of desflurane versus propofol anesthesia on postoperative delirium in elderly obese patients undergoing total knee replacement: A randomized, controlled, double-blinded clinical trial.
Topics: Aged; Anesthesia, General; Arthroplasty, Replacement, Knee; Cognitive Dysfunction; Delirium; Desflur | 2017 |
Postoperative emergence delirium in pediatric patients undergoing cataract surgery--a comparison of desflurane and sevoflurane.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Cataract Extraction; Ch | 2013 |
A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Delirium; Desflurane; Dexmedetomidine; Female; Hum | 2016 |
A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Delirium; Desflurane; Dexmedetomidine; Female; Hum | 2016 |
A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Delirium; Desflurane; Dexmedetomidine; Female; Hum | 2016 |
A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Delirium; Desflurane; Dexmedetomidine; Female; Hum | 2016 |
Early postoperative cognitive dysfunction and postoperative delirium after anaesthesia with various hypnotics: study protocol for a randomised controlled trial--the PINOCCHIO trial.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Cognition; Cognition Disorde | 2011 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Emergence delirium in children: a comparison of sevoflurane and desflurane anesthesia using the Paediatric Anesthesia Emergence Delirium scale.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalation; Carbon Dioxide; Child; Chil | 2013 |
Recovery profile and emergence delirium following sevoflurane and isoflurane anesthesia in children posted for cleft lip surgery.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Child, Preschool; Cleft Lip; Delirium; Double-B | 2012 |
Assessing behaviour in children emerging from anaesthesia: can we apply psychiatric diagnostic techniques?
Topics: Age Factors; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, | 2003 |
Isoflurane is associated with a similar incidence of emergence agitation/delirium as sevoflurane in young children--a randomized controlled study.
Topics: Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, Caudal; Anesthesia, General; Anesth | 2007 |
Tracheal extubation of deeply anesthetized pediatric patients: a comparison of isoflurane and sevoflurane.
Topics: Adolescent; Anesthetics, Inhalation; Arousal; Child; Child, Preschool; Delirium; Humans; Infant; Int | 1999 |
8 other studies available for isoflurane and Delirium of Mixed Origin
| Article | Year |
|---|---|
Involvement of acute neuroinflammation in postoperative delirium-like cognitive deficits in rats.
Topics: Animals; Brain; Cognition; Cognition Disorders; Cognitive Dysfunction; Cytokines; Delirium; Fear; Hi | 2018 |
Pain and delirium.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Delirium; Female; Humans; Isoflurane; Male; Met | 2014 |
The effect of sedation on the pediatric anesthesia emergence delirium scale.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Delirium; Female; Humans; Isoflurane; Male; Met | 2014 |
Sevoflurane and Isoflurane induce structural changes in brain vascular endothelial cells and increase blood-brain barrier permeability: Possible link to postoperative delirium and cognitive decline.
Topics: Aging; Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Capillary Permeability; Cognition Diso | 2015 |
[Effects of Sevoflurane or Desflurane Anesthesia on Perioperative Delirium in Elderly Patients Undergoing Surgical Repair of Hip Fracture].
Topics: Aged, 80 and over; Anesthesia Recovery Period; Anesthetics, Inhalation; Delirium; Desflurane; Female | 2015 |
Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia.
Topics: Amyloid beta-Protein Precursor; Anesthetics, Inhalation; Apoptosis; Blotting, Western; Cells, Cultur | 2006 |
Isoflurane vs sevoflurane in emergence delirium: a misleading conclusion.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Data Interpretation, St | 2008 |
Regarding sevoflurane and emergence agitation...again!
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Data Interpretation, St | 2008 |