Page last updated: 2024-10-29

isoflurane and Coronary Heart Disease

isoflurane has been researched along with Coronary Heart Disease in 97 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Research Excerpts

ExcerptRelevanceReference
"In patients without significant cardiovascular disease, the hemodynamic effects of sevoflurane and isoflurane are similar; however, the hemodynamic effects of sevoflurane in patients with hypertension and ischemic heart disease are unknown."9.08The hemodynamic and renal effects of sevoflurane and isoflurane in patients with coronary artery disease and chronic hypertension. Sevoflurane Ischemia Study Group. ( Ebert, T; Kharasch, ED; Muzi, M; Rooke, GA, 1996)
"Sevoflurane is associated with less tachycardia and coronary vasodilation than isoflurane and thus might be associated with less myocardial ischemia."9.08Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group. ( Ebert, TJ; Kharasch, ED; Muzi, M; Rooke, GA; Shroff, A, 1997)
"Early studies indicated that isoflurane caused coronary steal and should therefore be avoided in patients with coronary heart disease."8.81Isoflurane and coronary heart disease. ( Agnew, NM; Pennefather, SH; Russell, GN, 2002)
"The effect of isoflurane on regional myocardial metabolism and blood flow, when used as an adjunct to fentanyl-nitrous oxide anesthesia, to control intraoperative hypertension was investigated."7.67Control of intraoperative hypertension with isoflurane in patients with coronary artery disease: effects on regional myocardial blood flow and metabolism. ( Appelgren, L; Milocco, I; Ricksten, SE; Sahlman, L; William-Olsson, G, 1989)
"When isoflurane 1."5.28Effect of isoflurane on the extent of myocardial necrosis and on systemic hemodynamics, regional myocardial blood flow, and regional myocardial metabolism in dogs after coronary artery occlusion. ( Davis, RF; Sidi, A, 1989)
"In patients without significant cardiovascular disease, the hemodynamic effects of sevoflurane and isoflurane are similar; however, the hemodynamic effects of sevoflurane in patients with hypertension and ischemic heart disease are unknown."5.08The hemodynamic and renal effects of sevoflurane and isoflurane in patients with coronary artery disease and chronic hypertension. Sevoflurane Ischemia Study Group. ( Ebert, T; Kharasch, ED; Muzi, M; Rooke, GA, 1996)
"Sevoflurane is associated with less tachycardia and coronary vasodilation than isoflurane and thus might be associated with less myocardial ischemia."5.08Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group. ( Ebert, TJ; Kharasch, ED; Muzi, M; Rooke, GA; Shroff, A, 1997)
"Early studies indicated that isoflurane caused coronary steal and should therefore be avoided in patients with coronary heart disease."4.81Isoflurane and coronary heart disease. ( Agnew, NM; Pennefather, SH; Russell, GN, 2002)
"We evaluated the risk of myocardial ischemia under isoflurane anesthesia (vs."3.68Effects of steal-prone anatomy on intraoperative myocardial ischemia. The SPI Research Group. ( Hollenberg, M; Kao, A; Leung, JM; Mangano, DT; O'Kelly, BF, 1992)
" Studies were performed in open-chest fentanyl-anesthetized dogs before and during halothane (n = 8) or isoflurane (n = 8) anesthesia."3.68Role of systemic arterial pressure, heart rate, and derived variables in prediction of severity of myocardial ischemia during acute coronary occlusion in anesthetized dogs. ( Kien, ND; Moore, PG; Reitan, JA; Safwat, AM; White, DA, 1992)
"The effect of isoflurane on regional myocardial metabolism and blood flow, when used as an adjunct to fentanyl-nitrous oxide anesthesia, to control intraoperative hypertension was investigated."3.67Control of intraoperative hypertension with isoflurane in patients with coronary artery disease: effects on regional myocardial blood flow and metabolism. ( Appelgren, L; Milocco, I; Ricksten, SE; Sahlman, L; William-Olsson, G, 1989)
"The effects of isoflurane-induced hypotension to mean aortic pressures of 70 and 55 mmHg on global and regional right and left ventricular performance (ultrasonic dimension technique) and on coronary hemodynamics (electromagnetic flow probes) were studied in 12 open-chest dogs (anesthetized and paralyzed by continuous infusions of fentanyl and pancuronium) with critical coronary artery stenoses (micrometer-controlled snares) of the right and left anterior descending coronary arteries."3.67Isoflurane causes regional myocardial dysfunction in dogs with critical coronary artery stenoses. ( Foëx, P; Priebe, HJ, 1987)
"Coronary heart disease is an affliction that is common and has an adverse effect on patients' quality of life and survival while also raising the risk of intraoperative anesthesia."3.01Myocardial Protection by Desflurane: From Basic Mechanisms to Clinical Applications. ( Qin, H; Zhou, J, 2023)
"Nitrous oxide (N2O) has been implicated as a cause of myocardial ischemia."2.67No finding of increased myocardial ischemia during or after carotid endarterectomy under anesthesia with nitrous oxide. ( Benefiel, D; Cahalan, MK; Eger, EI; Kozmary, SV; Lampe, GH; Schiller, NB; Wauk, LZ; Whitendale, P, 1990)
"When nitrous oxide was added to isoflurane there was a fall in heart rate (-13%), a further reduction in systemic blood pressure (-18%) and myocardial oxygen consumption (-31%) and extraction (-17%) whereas all other variables including coronary blood flow remained unaltered."2.65Nitrous oxide augments the systemic and coronary haemodynamic effects of isoflurane in patients with ischaemic heart disease. ( Reiz, S, 1983)
"Distal to the critical stenosis, a transmural redistribution of myocardial blood flow (endocardial-epicardial ratio < 1) occurred with all concentrations of isoflurane."1.29Transmural redistribution of myocardial blood flow during isoflurane anesthesia and its effects on regional myocardial function in a canine model of fixed coronary stenosis. ( Gallagher, KP; Knight, PR; Martin, B; Ullrich, K; Wilton, NC, 1993)
"Isoflurane caused an increase in cardiac index that was not seen with halothane or enflurane (halothane vs isoflurane, P < 0."1.28Effects of surgical stress and volatile anesthetics on left ventricular global and regional function in patients with coronary artery disease. Evaluation by computer-assisted two-dimensional quantitative transesophageal echocardiography. ( Caidahl, K; Gustavsson, T; Houltz, E; Kirnö, K; Lamm, C; Milocco, I; Ricksten, SE, 1992)
"Isoflurane and fentanyl were chosen as anesthetics of current interest."1.28Effects of isoflurane and fentanyl on ischemic myocardium in dogs: assessment by end-systolic measurements. ( Chinzei, M; Chinzei, T; Iizuka, M; Morita, S; Numata, K; Ohya, T; Serizawa, T; Takahashi, H, 1991)
"Propranolol was administered intravenously and then measurements were made during imposition of a stenosis on the perfusion circuit sufficient to decrease systolic shortening by 30%."1.28Nitrous oxide does not worsen myocardial ischaemia following beta-receptor blockade in isoflurane anaesthetized dogs. ( Nathan, HJ, 1991)
"When nitrous oxide was added to 1."1.28Control of hemodynamics prevents worsening of myocardial ischemia when nitrous oxide is administered to isoflurane-anesthetized dogs. ( Nathan, HJ, 1989)
" A critical LAD-stenosis caused no major changes in the general dose-response pattern of isoflurane but further aggravated the depression of cardiac output and stroke volume induced by increasing concentrations of halothane."1.28Hemodynamic dose-responses to halothane and isoflurane are different in swine with and without critical coronary artery stenosis. ( Gilbert, M; Mori, M; Myhre, ES, 1989)
"When isoflurane 1."1.28Effect of isoflurane on the extent of myocardial necrosis and on systemic hemodynamics, regional myocardial blood flow, and regional myocardial metabolism in dogs after coronary artery occlusion. ( Davis, RF; Sidi, A, 1989)
"Treatment with nitrous oxide was associated with small increases in heart rate and systolic blood pressure (5 and 8%, respectively), as well as a 19% reduction in systolic shortening and a 30% fall in endo/epi blood flow ratio in the hypoperfused LAD region distal to the stenosis."1.27Nitrous oxide worsens myocardial ischemia in isoflurane-anesthetized dogs. ( Nathan, HJ, 1988)
"Halothane was compared to isoflurane and the question of whether major surgery might reduce FAR was investigated."1.27Isoflurane has a greater margin of safety than halothane in swine with and without major surgery or critical coronary stenosis. ( Gilbert, M; Roberts, SL; Tinker, JH, 1987)

Research

Studies (97)

TimeframeStudies, this research(%)All Research%
pre-199043 (44.33)18.7374
1990's45 (46.39)18.2507
2000's8 (8.25)29.6817
2010's0 (0.00)24.3611
2020's1 (1.03)2.80

Authors

AuthorsStudies
Qin, H1
Zhou, J1
Umbrain, V1
Shi, L1
Camu, F1
Teo, A1
Koh, KF1
Forlani, S2
Tomai, F2
De Paulis, R2
Turani, F1
Colella, DF1
Nardi, P1
De Notaris, S1
Moscarelli, M1
Magliano, G1
Crea, F1
Chiariello, L2
But, AK1
Durmus, M1
Toprak, HI1
Ozturk, E1
Demirbilek, S1
Ersoy, MO1
Behny, LR1
Venkatesh, BG1
Mehta, Y1
Kumar, A1
Trehan, N1
Foëx, P3
Jones, RM1
Reiz, S6
Kirihara, T1
Nozaki, F2
Fukushima, K2
Bastard, OG1
Carter, JG1
Moyers, JR2
Bross, BA1
Bålfors, E1
Sørensen, MB1
Ariola, S1
Friedman, A3
Truedsson, H1
Coriat, P1
Sprung, J1
Joseph, G1
Murray, K1
O'Hara, J1
Hohner, P2
Nancarrow, C1
Backman, C2
Häggmark, S2
Johansson, G2
Fridén, H1
Diamond, G2
Karp, K1
Spahn, DR2
Hu, WC2
Smith, LR2
Leone, BJ2
Wouters, PF1
Van Aken, H1
Marcus, MA1
Van De Velde, M1
Van Herck, A1
Flameng, W1
Wilton, NC1
Knight, PR3
Ullrich, K1
Martin, B1
Gallagher, KP3
Priebe, HJ5
Conzen, P2
Rooke, GA2
Ebert, T1
Muzi, M2
Kharasch, ED2
Cheng, DC2
Jiang, MT1
Asokumar, B1
Boylen, P1
Sandler, A1
Grundmann, U1
Müller, M1
Kleinschmidt, S1
Larsen, B1
Larsen, R3
Thrush, DN1
Houltz, E2
Caidahl, K2
Adin, C1
Gustavsson, T2
Ricksten, SE3
Fujita, Y1
Habazettl, H2
Corso, CO1
Messmer, K1
Yada, T1
Ebert, TJ1
Shroff, A1
Murray, JM1
Luney, SR1
Preckel, B1
Schlack, W1
Comfère, T1
Obal, D1
Barthel, H1
Thämer, V1
Penta de Peppo, A1
Colagrande, L1
Caprara, E1
Polisca, P1
De Matteis, G1
Ghini, AS1
Colella, D1
Park, KW1
Dai, HB1
Comunale, ME1
Gopal, A1
Sellke, FW1
Agnew, NM1
Pennefather, SH1
Russell, GN1
Leung, JM3
Hollenberg, M2
O'Kelly, BF2
Kao, A1
Mangano, DT3
Kirnö, K1
Lamm, C1
Milocco, I2
Kimura, H1
Kohyama, A1
Moore, PG2
Reitan, JA2
Kien, ND2
White, DA2
Safwat, AM2
Helman, JD1
Bellows, WH1
Pineda, N2
Roach, GW1
Reeves, JD1
Howse, J1
McEnany, MT1
Knutson, RM1
Gomez, MN1
Tinker, JH2
Veronee, CD1
McRae, RL1
Vollmar, B1
Hobbhahn, J1
Peter, K1
Slogoff, S1
Keats, AS1
Dear, WE1
Abadia, A1
Lawyer, JT1
Moulds, JP1
Williams, TM1
Goehner, P1
Cason, BA1
Mayer, N1
Zimpfer, M1
Steinbereithner, K1
Chinzei, M2
Morita, S2
Chinzei, T1
Takahashi, H1
Ohya, T1
Serizawa, T1
Iizuka, M1
Numata, K1
Wahr, JA1
Tait, AR2
Hantler, CB2
Nathan, HJ3
Pulley, DD1
Kirvassilis, GV1
Kelermenos, N1
Kater, K1
Barzilai, B1
Genton, RE1
Efstathiou, C1
Lappas, DG1
Thomson, IR1
Bowering, JB1
Hudson, RJ1
Frais, MA1
Rosenbloom, M1
Eichwede, F1
Komar, K1
Müller, R1
Grote, B1
Tarnow, J2
Hartman, JC4
Kampine, JP5
Schmeling, WT5
Warltier, DC5
Pagel, PS1
Goh, R1
Kitahata, H1
Arvieux, CC1
Videcoq, M1
Ramsay, JG1
Stone, JG2
Ryder, WA1
Kozmary, SV1
Lampe, GH1
Benefiel, D1
Cahalan, MK2
Wauk, LZ1
Whitendale, P1
Schiller, NB2
Eger, EI1
Kashimoto, S1
Oguchi, T1
Kume, M1
Kumazama, T1
Gross, JB1
Gilbert, M2
Mori, M1
Myhre, ES1
Kissin, I1
Gelman, S2
Bertha, BG1
Folts, JD1
Nugent, M1
Rusy, BF1
Sahlman, L1
Appelgren, L1
William-Olsson, G1
Dahlgren, G1
Ohqvist, G1
Brodin, LA1
Fischerström, A1
Settergren, G1
Davis, RF1
Sidi, A1
Stieglitz, P1
Dolman, J1
Godin, DV1
Moffitt, EA1
Sethna, DH1
Merin, RG2
al-Wathiqui, MH1
Smith, JS1
Roizen, MF1
Benefiel, DJ1
Beaupre, PN1
Sohn, YJ1
Byrd, BF1
Stoney, RJ1
Ehrenfeld, WK1
Lee, M1
Pollard, JB1
Hill, RF1
Lowe, JE1
Cummings, RG1
Simeone, DM1
Menius, JA1
Reves, JG1
Khambatta, HJ1
Sonntag, H2
Stephan, H1
Kettler, D1
Hilfiker, O1
Philbin, DM1
Wu, KS1
Lui, PW1
Lee, TY1
Chan, KH1
Yang, MW1
Kang, L1
Shai, SP1
Tang, GJ1
Lee, TK1
Lai, KT1
Roberts, SL1
Toyooka, H1
Inada, Y1
Tatekawa, S1
Traber, KB1
Günnicker, M1
Hirche, H1
Nommensen, CC1
Hess, W1
Sato, T1
Luciana, S1
Chen, TL1
Chao, CC1
Becker, LC1
Buffington, CW1
Romson, JL1
Levine, A1
Duttlinger, NC1
Huang, AH1
Lowenstein, E1
Markschies-Hornung, A1
Schulte-Sasse, U1
Ostman, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective Randomised Controled Trial: Comparison of Volatile Anaesthetics Sevoflurane vs. Isoflurane for Low-Flow General Anaesthesia for Abdominal Surgery[NCT00521612]82 participants (Actual)Interventional2007-09-30Completed
[NCT00005197]0 participants Observational1986-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

15 reviews available for isoflurane and Coronary Heart Disease

ArticleYear
Myocardial Protection by Desflurane: From Basic Mechanisms to Clinical Applications.
    Journal of cardiovascular pharmacology, 2023, 09-01, Volume: 82, Issue:3

    Topics: Anesthetics, Inhalation; Coronary Disease; Desflurane; Humans; Isoflurane; Quality of Life; Reactive

2023
Desflurane: a reappraisal.
    Acta anaesthesiologica Belgica, 2002, Volume: 53, Issue:3

    Topics: Anesthesia, Closed-Circuit; Anesthetics, Inhalation; Animals; Carbon Monoxide; Carbon Monoxide Poiso

2002
Off-pump coronary artery bypass grafting: a case report.
    AANA journal, 2006, Volume: 74, Issue:1

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

2006
Beta blockade in anaesthesia.
    Journal of clinical and hospital pharmacy, 1983, Volume: 8, Issue:2

    Topics: Adrenergic beta-Antagonists; Analgesics; Anesthesia; Coronary Disease; Drug Interactions; Enflurane;

1983
Clinical comparison of inhalation anaesthetic agents.
    British journal of anaesthesia, 1984, Volume: 56 Suppl 1

    Topics: Anesthesia, Inhalation; Cardiovascular Diseases; Coronary Disease; Drug Interactions; Enflurane; Fem

1984
Circulatory effects of desflurane.
    Anaesthesia, 1995, Volume: 50 Suppl

    Topics: Anesthesia; Anesthetics, Inhalation; Coronary Disease; Desflurane; Heart Rate; Hemodynamics; Humans;

1995
[Inhalation anesthetics in patients with coronary heart disease: pro].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1993, Volume: 28, Issue:1

    Topics: Anesthesia, Inhalation; Animals; Coronary Disease; Enflurane; Halothane; Humans; Isoflurane

1993
[Inhalation anesthetics in patients with coronary heart disease: contra].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1993, Volume: 28, Issue:1

    Topics: Anesthesia, Inhalation; Animals; Coronary Disease; Enflurane; Halothane; Humans; Isoflurane

1993
Isoflurane and coronary heart disease.
    Anaesthesia, 2002, Volume: 57, Issue:4

    Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Cardiotonic Agents; Coronary Disease; Humans; Ische

2002
[Volatile anesthetics in coronary disease].
    Klinische Anasthesiologie und Intensivtherapie, 1991, Volume: 41

    Topics: Anesthesia, Inhalation; Animals; Coronary Circulation; Coronary Disease; Dogs; Enflurane; Humans; Is

1991
Coronary vasomotion during anesthesia.
    Acta chirurgica Scandinavica. Supplementum, 1989, Volume: 550

    Topics: Anesthesia, General; Cardiac Surgical Procedures; Coronary Circulation; Coronary Disease; Coronary V

1989
Isoflurane and coronary hemodynamics.
    Anesthesiology, 1989, Volume: 71, Issue:6

    Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Guinea Pigs; Humans; Isoflurane; Species Spec

1989
[Management of peroperative hypertensive crises].
    Annales francaises d'anesthesie et de reanimation, 1988, Volume: 7, Issue:2

    Topics: Adrenergic beta-Antagonists; Anesthesia, General; Calcium Channel Blockers; Clonidine; Coronary Dise

1988
Disadvantages of isoflurane in coronary artery disease.
    Acta anaesthesiologica Belgica, 1988, Volume: 39, Issue:3 Suppl 2

    Topics: Coronary Disease; Coronary Vessels; Depression, Chemical; Humans; Hypotension; Isoflurane; Tachycard

1988
The coronary circulation and myocardial oxygenation in coronary artery disease: effects of anesthesia.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:4

    Topics: Anesthesia; Calcium Chloride; Coronary Artery Bypass; Coronary Circulation; Coronary Disease; Digoxi

1986

Trials

17 trials available for isoflurane and Coronary Heart Disease

ArticleYear
Preoperative shift from glibenclamide to insulin is cardioprotective in diabetic patients undergoing coronary artery bypass surgery.
    The Journal of cardiovascular surgery, 2004, Volume: 45, Issue:2

    Topics: Aged; Anesthetics, Inhalation; Angina Pectoris; Cardiotonic Agents; Coronary Disease; Creatine Kinas

2004
Hemodynamic, hepatorenal, and postoperative effects of desflurane-fentanyl and midazolam-fentanyl anesthesia in coronary artery bypass surgery.
    Journal of cardiothoracic and vascular anesthesia, 2005, Volume: 19, Issue:5

    Topics: Adult; Anesthetics, Combined; Anesthetics, General; Biomarkers; Coronary Artery Bypass; Coronary Dis

2005
Nitrous oxide augments the systemic and coronary haemodynamic effects of isoflurane in patients with ischaemic heart disease.
    Acta anaesthesiologica Scandinavica, 1983, Volume: 27, Issue:6

    Topics: Aged; Carbon Dioxide; Clinical Trials as Topic; Coronary Circulation; Coronary Disease; Drug Synergi

1983
Anaesthesia for abdominal vascular surgery in patients with coronary artery disease (CAD), Part I: Isoflurane produces dose-dependent coronary vasodilation.
    Acta anaesthesiologica Scandinavica, 1994, Volume: 38, Issue:8

    Topics: Abdomen; Aged; Aged, 80 and over; Anesthesia; Coronary Circulation; Coronary Disease; Dose-Response

1994
Anaesthesia for abdominal aortic surgery in patients with coronary artery disease, Part II: Effects of nitrous oxide on systemic and coronary haemodynamics, regional ventricular function and incidence of myocardial ischaemia.
    Acta anaesthesiologica Scandinavica, 1994, Volume: 38, Issue:8

    Topics: Abdomen; Anesthesia; Coronary Circulation; Coronary Disease; Female; Fentanyl; Hemodynamics; Humans;

1994
The hemodynamic and renal effects of sevoflurane and isoflurane in patients with coronary artery disease and chronic hypertension. Sevoflurane Ischemia Study Group.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Pressure; Blood Urea Nitrogen; C

1996
Cardiovascular effects of desflurane and isoflurane in patients with coronary artery disease.
    Acta anaesthesiologica Scandinavica, 1996, Volume: 40, Issue:9

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Inhalation; Blood Pressure; Cardiac Output; Coronary

1996
Effects of halothane and isoflurane on left ventricular diastolic function during surgical stress in patients with coronary artery disease.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:7

    Topics: Adult; Aged; Anesthetics, Inhalation; Coronary Disease; Diastole; Echocardiography; Female; Halothan

1997
Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Coronary Disease; Ethers; Female; Heart Dis

1997
Beneficial impact of isoflurane during coronary bypass surgery on troponin I release.
    Giornale italiano di cardiologia, 1999, Volume: 29, Issue:9

    Topics: Aged; Analysis of Variance; Anesthetics, Inhalation; Angina Pectoris; Chronic Disease; Coronary Arte

1999
Isoflurane anesthesia and myocardial ischemia: comparative risk versus sufentanil anesthesia in patients undergoing coronary artery bypass graft surgery. The SPI (Study of Perioperative Ischemia) Research Group.
    Anesthesiology, 1991, Volume: 74, Issue:5

    Topics: Adult; Aged; Anesthetics; Coronary Artery Bypass; Coronary Disease; Female; Fentanyl; Humans; Isoflu

1991
Regional and global myocardial circulatory and metabolic effects of isoflurane and halothane in patients with steal-prone coronary anatomy.
    Anesthesiology, 1991, Volume: 75, Issue:5

    Topics: Adult; Aged; Coronary Artery Bypass; Coronary Circulation; Coronary Disease; Female; Halothane; Hear

1991
A comparison of desflurane and isoflurane in patients undergoing coronary artery surgery.
    Anesthesiology, 1991, Volume: 75, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics; Cardiopulmonary Bypass; Coronary Disease; Desflurane; F

1991
[Preoperative treatment with beta-receptor blockers and isoflurane anesthesia. Hemodynamic interactions in patients with coronary disease].
    Der Anaesthesist, 1990, Volume: 39, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Anesthesia, Inhalation; Atenolol; Bisoprolol; Coronary Dis

1990
No finding of increased myocardial ischemia during or after carotid endarterectomy under anesthesia with nitrous oxide.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:6

    Topics: Aged; Anesthesia, Inhalation; Coronary Disease; Electrocardiography; Endarterectomy; Female; Hemodyn

1990
Does anesthetic technique make a difference? Augmentation of systolic blood pressure during carotid endarterectomy: effects of phenylephrine versus light anesthesia and of isoflurane versus halothane on the incidence of myocardial ischemia.
    Anesthesiology, 1988, Volume: 69, Issue:6

    Topics: Aged; Anesthesia; Blood Pressure; Carotid Artery Diseases; Cerebrovascular Circulation; Coronary Dis

1988
[Hemodynamics of coronary surgery patients under isoflurane and neuroleptanalgesia].
    Der Anaesthesist, 1986, Volume: 35, Issue:6

    Topics: Adult; Anesthesia; Blood Pressure; Cardiac Output; Coronary Disease; Female; Heart Rate; Humans; Iso

1986

Other Studies

65 other studies available for isoflurane and Coronary Heart Disease

ArticleYear
Isoflurane and coronary steal.
    Anaesthesia, 2003, Volume: 58, Issue:1

    Topics: Anesthetics, Inhalation; Coronary Artery Bypass; Coronary Disease; Humans; Intraoperative Complicati

2003
Comparison of sevoflurane and isoflurane in OPCAB surgery.
    Annals of cardiac anaesthesia, 2007, Volume: 10, Issue:1

    Topics: Aged; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure;

2007
[A comparative study of the effect of halothane, enflurane and isoflurane on the ischemic rat heart using a working heart preparation].
    Masui. The Japanese journal of anesthesiology, 1984, Volume: 33, Issue:10

    Topics: Anesthesia; Animals; Coronary Disease; Enflurane; Halothane; Hemodynamics; In Vitro Techniques; Isof

1984
Circulatory effects of isoflurane in patients with ischemic heart disease: a comparison with halothane.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:7

    Topics: Anesthesia, Inhalation; Blood Pressure; Cardiac Output; Coronary Artery Bypass; Coronary Disease; Fe

1984
Isoflurane--a powerful coronary vasodilator in patients with coronary artery disease.
    Anesthesiology, 1983, Volume: 59, Issue:2

    Topics: Aged; Coronary Disease; Coronary Vessels; Electrocardiography; Female; Hemodynamics; Humans; Isoflur

1983
Electrocardiographic changes during isoflurane anesthesia suggesting asymptomatic coronary artery disease in three patients.
    Anesthesiology, 1995, Volume: 83, Issue:3

    Topics: Aged; Anesthesia; Coronary Circulation; Coronary Disease; Electrocardiography; Humans; Isoflurane; M

1995
Pacing-induced left ventricular asynchronies in dogs with critical coronary stenosis: mechanisms and effect of anesthetics.
    Journal of cardiothoracic and vascular anesthesia, 1993, Volume: 7, Issue:6

    Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Cardiac Pacing, Artifici

1993
Effects of halothane and isoflurane on collateral dependent myocardium in chronically instrumented dogs.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:3

    Topics: Anesthesia, Inhalation; Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Dip

1993
Transmural redistribution of myocardial blood flow during isoflurane anesthesia and its effects on regional myocardial function in a canine model of fixed coronary stenosis.
    Anesthesiology, 1993, Volume: 78, Issue:3

    Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Constriction, Pathologic; Coronary Circulation; Cor

1993
Comparison of nifedipine and metoprolol on collateral coronary blood flow in a swine model of chronic coronary obstruction and acute ischaemia during isoflurane anaesthesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:2

    Topics: Adrenergic beta-Antagonists; Anesthetics, Inhalation; Animals; Calcium Channel Blockers; Chronic Dis

1996
Anesthesia for laser transmyocardial revascularization.
    Journal of cardiothoracic and vascular anesthesia, 1997, Volume: 11, Issue:4

    Topics: Aluminum Silicates; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesth

1997
Comparative effects of hypotension due to isoflurane, nitroglycerin, and adenosine on subendocardial microcirculation: observation of the in situ beating swine heart under critical stenosis.
    Anesthesiology, 1997, Volume: 87, Issue:2

    Topics: Adenosine; Animals; Blood Pressure; Coronary Disease; Endocardium; Female; Hemodynamics; Hydrogen-Io

1997
Fatal cardiac ischaemia associated with prolonged desflurane anaesthesia and administration of exogenous catecholamines.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:12

    Topics: Aged; Anesthetics, Inhalation; Blood Pressure; Bradycardia; Cardiotonic Agents; Coronary Disease; Cr

1998
Effects of enflurane, isoflurane, sevoflurane and desflurane on reperfusion injury after regional myocardial ischaemia in the rabbit heart in vivo.
    British journal of anaesthesia, 1998, Volume: 81, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Coronary Disease; Desflurane; Enflurane; Hemodynamics; Isoflurane;

1998
Dilation by isoflurane of preconstricted, very small arterioles from human right atrium is mediated in part by K(+)-ATP channel opening.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine

2000
Effects of steal-prone anatomy on intraoperative myocardial ischemia. The SPI Research Group.
    Journal of the American College of Cardiology, 1992, Nov-01, Volume: 20, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Chi-Square Distribution; Collateral Circulation; Coronary Circula

1992
Effects of surgical stress and volatile anesthetics on left ventricular global and regional function in patients with coronary artery disease. Evaluation by computer-assisted two-dimensional quantitative transesophageal echocardiography.
    Anesthesia and analgesia, 1992, Volume: 75, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics; Coronary Disease; Diagnosis, Computer-Assisted; Echocar

1992
[Effects of deliberate hypotension on the ischemic heart during isoflurane anesthesia--a comparison of prostaglandin E1 and sodium nitroprusside].
    Masui. The Japanese journal of anesthesiology, 1992, Volume: 41, Issue:9

    Topics: Alprostadil; Anesthesia, Inhalation; Animals; Coronary Circulation; Coronary Disease; Dogs; Hemodyna

1992
Role of systemic arterial pressure, heart rate, and derived variables in prediction of severity of myocardial ischemia during acute coronary occlusion in anesthetized dogs.
    Anesthesia and analgesia, 1992, Volume: 75, Issue:3

    Topics: Anesthesia; Animals; Arteries; Blood Pressure; Body Temperature; Coronary Disease; Coronary Vessels;

1992
The risk of myocardial ischemia in patients receiving desflurane versus sufentanil anesthesia for coronary artery bypass graft surgery. The S.P.I. Research Group.
    Anesthesiology, 1992, Volume: 77, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Anesthesia, Intravenous; Coronary Artery Byp

1992
Dose-response relationship of isoflurane and halothane versus coronary perfusion pressures. Effects on flow redistribution in a collateralized chronic swine model.
    Anesthesiology, 1992, Volume: 76, Issue:1

    Topics: Animals; Blood Pressure; Collateral Circulation; Contraindications; Coronary Circulation; Coronary D

1992
Influence of anesthesia on the threshold of pacing-induced ischemia.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:1

    Topics: Animals; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Disease; Dogs; Halothane; Heart;

1992
Steal-prone coronary anatomy and myocardial ischemia associated with four primary anesthetic agents in humans.
    Anesthesia and analgesia, 1991, Volume: 72, Issue:1

    Topics: Anesthetics; Coronary Disease; Disease Susceptibility; Enflurane; Fentanyl; Halothane; Humans; Hypot

1991
Isoflurane impairs the function of ischemic myocardium in acutely but not in chronically instrumented dogs.
    Anesthesia and analgesia, 1991, Volume: 73, Issue:1

    Topics: Animals; Coronary Disease; Dogs; Female; Heart; Hemodynamics; Isoflurane; Male

1991
Effects of isoflurane and fentanyl on ischemic myocardium in dogs: assessment by end-systolic measurements.
    Journal of cardiothoracic and vascular anesthesia, 1991, Volume: 5, Issue:3

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Aorta; Blood Pressure; Cardiac Output; Cor

1991
Hemodynamic alterations and regional myocardial blood flow during supraceliac aortic occlusion in dogs with a critical coronary stenosis.
    Journal of cardiothoracic and vascular anesthesia, 1991, Volume: 5, Issue:1

    Topics: Anesthesia, Inhalation; Animals; Aorta, Thoracic; Atrial Function, Left; Blood Pressure; Cardiac Out

1991
Nitrous oxide does not worsen myocardial ischaemia following beta-receptor blockade in isoflurane anaesthetized dogs.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1991, Volume: 38, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Atrial Function, Left; Blood Pressure; Cardiac Output; Coronary Cir

1991
No evidence for blood flow redistribution with isoflurane or halothane during acute coronary artery occlusion in fentanyl-anesthetized dogs.
    Anesthesiology, 1991, Volume: 75, Issue:5

    Topics: Animals; Coronary Disease; Coronary Vessels; Dogs; Female; Fentanyl; Halothane; Hemodynamics; Isoflu

1991
Alterations in collateral blood flow produced by isoflurane in a chronically instrumented canine model of multivessel coronary artery disease.
    Anesthesiology, 1991, Volume: 74, Issue:1

    Topics: Adenosine; Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Disease Models,

1991
Influence of desflurane on regional distribution of coronary blood flow in a chronically instrumented canine model of multivessel coronary artery obstruction.
    Anesthesia and analgesia, 1991, Volume: 72, Issue:3

    Topics: Anesthetics; Animals; Coronary Circulation; Coronary Disease; Desflurane; Dogs; Female; Hemodynamics

1991
[Effects of sevoflurane, isoflurane, and halothane on regional myocardial blood flow in the ischemic canine heart].
    Masui. The Japanese journal of anesthesiology, 1991, Volume: 40, Issue:2

    Topics: Anesthetics; Animals; Coronary Circulation; Coronary Disease; Dogs; Ethers; Halothane; Isoflurane; M

1991
Dose-related effects of isoflurane associated with low plasma concentrations of verapamil on global and regional function in normal and compromised canine myocardium.
    British journal of anaesthesia, 1991, Volume: 66, Issue:6

    Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Dose-

1991
Actions of isoflurane on myocardial perfusion in chronically instrumented dogs with poor, moderate, or well-developed coronary collaterals.
    Journal of cardiothoracic anesthesia, 1990, Volume: 4, Issue:6

    Topics: Anesthesia, Inhalation; Animals; Blood Flow Velocity; Blood Pressure; Cardiac Output; Catheterizatio

1990
Volatile anesthetics and regional myocardial perfusion in chronically instrumented dogs: halothane versus isoflurane in a single-vessel disease model with enhanced collateral development.
    Journal of cardiothoracic anesthesia, 1990, Volume: 4, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Dep

1990
Interaction between calcium channel blockers and volatile anaesthetics in the rat heart-lung preparation.
    British journal of anaesthesia, 1990, Volume: 64, Issue:5

    Topics: Anesthetics; Animals; Calcium Channel Blockers; Coronary Disease; Diltiazem; Drug Interactions; Enfl

1990
Control of hemodynamics prevents worsening of myocardial ischemia when nitrous oxide is administered to isoflurane-anesthetized dogs.
    Anesthesiology, 1989, Volume: 71, Issue:5

    Topics: Anesthesia, General; Animals; Coronary Circulation; Coronary Disease; Dogs; Female; Heart; Hemodynam

1989
Myocardial ischemia during isoflurane anesthesia: the effect of substituting halothane.
    Anesthesiology, 1989, Volume: 70, Issue:6

    Topics: Adult; Anesthesia, Inhalation; Coronary Disease; Electrocardiography; Halothane; Humans; Isoflurane;

1989
Hemodynamic dose-responses to halothane and isoflurane are different in swine with and without critical coronary artery stenosis.
    Anesthesia and analgesia, 1989, Volume: 68, Issue:6

    Topics: Animals; Constriction, Pathologic; Coronary Disease; Dose-Response Relationship, Drug; Halothane; He

1989
Isoflurane: myocardial ischemia without coronary steal?
    Anesthesia and analgesia, 1989, Volume: 68, Issue:6

    Topics: Coronary Circulation; Coronary Disease; Halothane; Humans; Isoflurane

1989
Halothane, but not isoflurane or enflurane, protects against spontaneous and epinephrine-exacerbated acute thrombus formation in stenosed dog coronary arteries.
    Anesthesiology, 1989, Volume: 71, Issue:1

    Topics: Animals; Coronary Circulation; Coronary Disease; Coronary Thrombosis; Dogs; Enflurane; Epinephrine;

1989
Control of intraoperative hypertension with isoflurane in patients with coronary artery disease: effects on regional myocardial blood flow and metabolism.
    Anesthesia and analgesia, 1989, Volume: 68, Issue:2

    Topics: Adult; Aged; Anesthesia, General; Coronary Artery Bypass; Coronary Circulation; Coronary Disease; Hu

1989
Isoflurane and intravenous anesthesia used for induction before coronary artery bypass grafting.
    Acta anaesthesiologica Scandinavica, 1989, Volume: 33, Issue:2

    Topics: Aged; Anesthesia, Intravenous; Blood Pressure; Coronary Artery Bypass; Coronary Disease; Female; Hem

1989
Effect of isoflurane on the extent of myocardial necrosis and on systemic hemodynamics, regional myocardial blood flow, and regional myocardial metabolism in dogs after coronary artery occlusion.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:5

    Topics: Animals; Arterial Occlusive Diseases; Coronary Circulation; Coronary Disease; Dogs; Female; Hemodyna

1989
Myocardial ischaemic/reperfusion injury in the anaesthetized rabbit: comparative effects of halothane and isoflurane.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:4

    Topics: Adenosine Triphosphatases; Anesthesia, Inhalation; Animals; Coronary Disease; Halothane; Hypotension

1986
Cardiovascular effects of isoflurane in man.
    Acta anaesthesiologica Belgica, 1988, Volume: 39, Issue:3 Suppl 2

    Topics: Coronary Circulation; Coronary Disease; Enflurane; Halothane; Heart; Hemodynamics; Humans; Isofluran

1988
Recovery of contractile function of stunned myocardium in chronically instrumented dogs is enhanced by halothane or isoflurane.
    Anesthesiology, 1988, Volume: 69, Issue:4

    Topics: Anesthesia; Animals; Consciousness; Coronary Disease; Dogs; Female; Halothane; Isoflurane; Male; Myo

1988
[The effects of prostaglandin I2 on coronary circulation in experimental canine ischemic heart during isoflurane anesthesia].
    Masui. The Japanese journal of anesthesiology, 1987, Volume: 36, Issue:6

    Topics: Anesthesia; Animals; Coronary Circulation; Coronary Disease; Dogs; Epoprostenol; Isoflurane; Vascula

1987
Nitrous oxide worsens myocardial ischemia in isoflurane-anesthetized dogs.
    Anesthesiology, 1988, Volume: 68, Issue:3

    Topics: Anesthesia, Inhalation; Animals; Coronary Circulation; Coronary Disease; Dogs; Female; Isoflurane; M

1988
Myocardial tolerance to total ischemia in the dog anesthetized with halothane or isoflurane.
    Anesthesiology, 1988, Volume: 69, Issue:1

    Topics: Adaptation, Physiological; Anesthesia, Inhalation; Animals; Coronary Disease; Dogs; Halothane; Heart

1988
Isoflurane causes more severe regional myocardial dysfunction than halothane in dogs with a critical coronary artery stenosis.
    Anesthesiology, 1988, Volume: 69, Issue:1

    Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Female; Halothane; Hemodynamics; Isoflurane;

1988
Global and regional myocardial blood flow and metabolism during equipotent halothane and isoflurane anesthesia in patients with coronary artery disease.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia; Blood Flow Velocity; Coronary Circulation; Coronary Dise

1988
[Isoflurane: coronary blood flow and myocardial metabolism in patients with coronary heart disease].
    Der Anaesthesist, 1986, Volume: 35, Issue:5

    Topics: Aged; Anesthesia; Coronary Artery Bypass; Coronary Circulation; Coronary Disease; Hemodynamics; Huma

1986
Cardiovascular effects of isoflurane in patients with poor left ventricular function undergoing coronary bypass grafting.
    Ma zui xue za zhi = Anaesthesiologica Sinica, 1986, Volume: 24, Issue:3

    Topics: Anesthesia; Coronary Artery Bypass; Coronary Disease; Female; Hemodynamics; Humans; Isoflurane; Male

1986
Isoflurane has a greater margin of safety than halothane in swine with and without major surgery or critical coronary stenosis.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:6

    Topics: Animals; Coronary Disease; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Halothane

1987
Is isoflurane dangerous for the patient with coronary artery disease?
    Anesthesiology, 1987, Volume: 67, Issue:2

    Topics: Anesthesia, Inhalation; Coronary Circulation; Coronary Disease; Humans; Isoflurane; Myocardial Contr

1987
[Effect of isoflurane, fentanyl and noxious stimuli on ischemic myocardium in dogs].
    Masui. The Japanese journal of anesthesiology, 1987, Volume: 36, Issue:4

    Topics: Animals; Coronary Disease; Dogs; Fentanyl; Heart; Hemodynamics; Isoflurane

1987
Effects of isoflurane on myocardial blood flow, function, and oxygen consumption in the presence of critical coronary stenosis in dogs.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:11

    Topics: Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Female; Heart; Isoflurane;

1987
[Effects of verapamil on recovery of postischemic cardiac function under 2 MAC enflurane and isoflurane anesthesia in the isolated rat heart].
    Masui. The Japanese journal of anesthesiology, 1986, Volume: 35, Issue:7

    Topics: Anesthesia, Inhalation; Animals; Coronary Circulation; Coronary Disease; Enflurane; Hemodynamics; In

1986
Haemodynamic effects of isoflurane in Chinese patients with ischemic heart disease.
    Ma zui xue za zhi = Anaesthesiologica Sinica, 1986, Volume: 24, Issue:1

    Topics: Anesthesia, Inhalation; Asian People; Coronary Disease; Female; Hemodynamics; Humans; Isoflurane; Ma

1986
Is isoflurane dangerous for the patient with coronary artery disease?
    Anesthesiology, 1987, Volume: 66, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Coronary Circulation; Coronary Disease; Humans; Isoflurane; Risk; V

1987
Isoflurane induces coronary steal in a canine model of chronic coronary occlusion.
    Anesthesiology, 1987, Volume: 66, Issue:3

    Topics: Adenosine; Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Dogs; Female; Ha

1987
Isoflurane causes regional myocardial dysfunction in dogs with critical coronary artery stenoses.
    Anesthesiology, 1987, Volume: 66, Issue:3

    Topics: Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Female; Hypotension; Isoflu

1987
Is anesthesia beneficial for the ischemic heart? III.
    Anesthesiology, 1986, Volume: 64, Issue:2

    Topics: Adult; Age Factors; Aged; Anesthesia; Coronary Circulation; Coronary Disease; Hemodynamics; Humans;

1986
Isoflurane improves the tolerance to pacing-induced myocardial ischemia.
    Anesthesiology, 1986, Volume: 64, Issue:2

    Topics: Adult; Aged; Angina Pectoris; Cardiac Output; Cardiac Pacing, Artificial; Coronary Circulation; Coro

1986
Regional coronary hemodynamics during isoflurane-nitrous oxide anesthesia in patients with ischemic heart disease.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:6

    Topics: Aged; Anesthesia, Inhalation; Blood Pressure; Coronary Circulation; Coronary Disease; Drug Combinati

1985