isoflurane has been researched along with Cognition Disorders in 70 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We aimed to investigate whether apigenin can attenuate isoflurane exposure-induced cognitive decline by regulating histone acetylation and inflammatory signaling." | 7.85 | Apigenin attenuates isoflurane-induced cognitive dysfunction via epigenetic regulation and neuroinflammation in aged rats. ( Chen, L; Jiang, C; Liu, N; Xie, W; Zhuang, W, 2017) |
| "To investigate effects of isoflurane anesthesia of different time interval on acute injury of brain function in neonatal rats with consistent total time of isoflurane anesthesia." | 7.83 | [Acute injury to ce.rebral function produced by isoflurane anesthesia given at different time interval in neonatal rats] ( Fang, X; Hao, J; Li, M; Tang, J; Yang, J; Zhang, Q, 2016) |
| "Isoflurane possesses neurotoxicity and can induce cognitive deficits, particularly in aging mammals." | 7.81 | A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice. ( Hao, S; Ji, M; Li, H; Li, K; Sun, X; Wu, J; Yang, J; Zhang, H, 2015) |
| "This study investigated the role of glycogen synthase kinase-3β (GSK-3β) in isoflurane-induced neuroinflammation and cognitive dysfunction in aged rats." | 7.79 | Role of GSK-3β in isoflurane-induced neuroinflammation and cognitive dysfunction in aged rats. ( Chen, X; Chen, YL; Li, SY; Luo, AL; Tan, L; Wang, JT; Xiang, Q; Zhao, YL, 2013) |
| "We are uncertain whether maintenance with propofol-based TIVA or with inhalational agents affect incidences of postoperative delirium, mortality, or length of hospital stay because certainty of the evidence was very low." | 4.98 | Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery. ( Alderson, P; Lewis, SR; Miller, D; Pritchard, MW; Schofield-Robinson, OJ; Shelton, CL; Smith, AF, 2018) |
| " To test these hypotheses, 6- to 8-week old male mice were subjected to right carotid artery exposure under isoflurane anesthesia." | 4.02 | Toll-like receptor 2 activation and up-regulation by high mobility group box-1 contribute to post-operative neuroinflammation and cognitive dysfunction in mice. ( Lin, F; Pan, L; Shan, W; Zheng, Y; Zuo, Z, 2021) |
| " We aimed to investigate whether apigenin can attenuate isoflurane exposure-induced cognitive decline by regulating histone acetylation and inflammatory signaling." | 3.85 | Apigenin attenuates isoflurane-induced cognitive dysfunction via epigenetic regulation and neuroinflammation in aged rats. ( Chen, L; Jiang, C; Liu, N; Xie, W; Zhuang, W, 2017) |
| "To investigate effects of isoflurane anesthesia of different time interval on acute injury of brain function in neonatal rats with consistent total time of isoflurane anesthesia." | 3.83 | [Acute injury to ce.rebral function produced by isoflurane anesthesia given at different time interval in neonatal rats] ( Fang, X; Hao, J; Li, M; Tang, J; Yang, J; Zhang, Q, 2016) |
| "Isoflurane possesses neurotoxicity and can induce cognitive deficits, particularly in aging mammals." | 3.81 | A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice. ( Hao, S; Ji, M; Li, H; Li, K; Sun, X; Wu, J; Yang, J; Zhang, H, 2015) |
| "This study investigated the role of glycogen synthase kinase-3β (GSK-3β) in isoflurane-induced neuroinflammation and cognitive dysfunction in aged rats." | 3.79 | Role of GSK-3β in isoflurane-induced neuroinflammation and cognitive dysfunction in aged rats. ( Chen, X; Chen, YL; Li, SY; Luo, AL; Tan, L; Wang, JT; Xiang, Q; Zhao, YL, 2013) |
| "Desflurane was associated with a faster early recovery than sevoflurane in elderly patients." | 2.78 | Post-operative cognitive functions after general anesthesia with sevoflurane and desflurane in South Asian elderly. ( Deepak, TS; Kempegowda, P; Kumar, KS; Vadlamani, S, 2013) |
| "Hypotension was treated with fluids and vasopressors using a standardised algorithm." | 2.76 | Effect of auditory evoked potential-guided anaesthesia on consumption of anaesthetics and early postoperative cognitive dysfunction: a randomised controlled trial. ( Berggren, L; Gupta, A; Hallén, JL; Jildenstål, PK; Rawal, N, 2011) |
| "Desflurane was associated with reduced early cognitive dysfunction." | 2.76 | The influence of propofol or desflurane on postoperative cognitive dysfunction in patients undergoing coronary artery bypass surgery. ( Andrews, DT; Newman, SN; Pang, J; Royse, AG; Royse, CF; Stygall, J; Williams, Z, 2011) |
| "Thus, we hypothesised that intestinal dysbacteriosis caused by anaesthesia/surgery induces POCD." | 1.51 | Intestinal dysbacteriosis mediates the reference memory deficit induced by anaesthesia/surgery in aged mice. ( Chen, XM; Gu, XY; Jiang, XL; Qin, Y; Shen, L; Su, DS; Yang, YT; Yu, WF; Zhang, X; Zhou, XX, 2019) |
| "Melatonin pretreatment were conducted before anesthesia for 7 Days." | 1.43 | Melatonin pretreatment prevents isoflurane-induced cognitive dysfunction by modulating sleep-wake rhythm in mice. ( Chu, S; Cui, Y; Gu, X; Ma, Z; Qian, Y; Song, J; Xia, T, 2016) |
| "Taurine pretreatment dose-dependently inhibited isoflurane-induced increase in expression of ER stress biomarkers except for P-EIF2α and ATF-4, and reversed isoflurane-induced changes in apoptosis-related proteins." | 1.43 | Taurine Pretreatment Prevents Isoflurane-Induced Cognitive Impairment by Inhibiting ER Stress-Mediated Activation of Apoptosis Pathways in the Hippocampus in Aged Rats. ( Hou, D; Hou, J; Li, D; Li, H; Zhang, Y, 2016) |
| "Melatonin is an endogenous hormone with neuroprotective effects." | 1.39 | Melatonin attenuates isoflurane-induced acute memory impairments in aged rats. ( Chui, D; Guo, X; Li, Z; Liu, Y; Ni, C; Qian, M; Tang, Y; Tian, X; Zhou, Y, 2013) |
| "When isoflurane was used, the learning and memory did not change after CPB." | 1.39 | Isoflurane prevents neurocognitive dysfunction after cardiopulmonary bypass in rats. ( Deng, Y; Li, W; Su, D; Wang, S; Wang, X; Xu, H; Zheng, B, 2013) |
| "Isoflurane-treated rats had fewer correct reactions and initiative avoidances in the Y-maze test 24 and 48 h after 2 h of isoflurane anesthesia compared with control group rats (p<0." | 1.38 | Involvement of neuronal nitric oxide synthase in cognitive impairment in isoflurane-treated rats. ( Duan, KM; Li, G; Ouyang, W; Yan, XB, 2012) |
| "Isoflurane may not cause long-lasting neuropathological changes." | 1.38 | Lidocaine attenuates cognitive impairment after isoflurane anesthesia in old rats. ( Cao, L; Li, J; Lin, D; Wang, Z; Washington, JM; Zuo, Z, 2012) |
| "The isoflurane anaesthesia treatment increased the escape latency contrast to propofol anaesthesia group." | 1.38 | Changes of learning and memory in aged rats after isoflurane inhalational anaesthesia correlated with hippocampal acetylcholine level. ( Feng, C; Jia, X; Wang, H; Wang, Y; Wu, A; Xu, Z; Yue, Y, 2012) |
| "Isoflurane was administered to 16-month-old rats at one minimum alveolar concentration for 4 h." | 1.36 | Isoflurane does not affect brain cell death, hippocampal neurogenesis, or long-term neurocognitive outcome in aged rats. ( Alvi, RS; Bell, JS; Bickler, PE; Chiu, C; Dai, R; Dowlatshahi, M; Hrubos, MW; Ku, B; Lee, MT; May, Ld; Russell, I; Sall, JW; Stratmann, G, 2010) |
| "Rats treated with isoflurane had the best cognitive recovery (p < 0." | 1.33 | Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats. ( Alexander, H; Clark, RS; Dixon, CE; Jenkins, L; Kochanek, PM; Statler, KD; Vagni, V, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (2.86) | 18.2507 |
| 2000's | 9 (12.86) | 29.6817 |
| 2010's | 58 (82.86) | 24.3611 |
| 2020's | 1 (1.43) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, F | 1 |
| Shan, W | 1 |
| Zheng, Y | 1 |
| Pan, L | 1 |
| Zuo, Z | 4 |
| Chen, L | 2 |
| Xie, W | 2 |
| Zhuang, W | 1 |
| Jiang, C | 1 |
| Liu, N | 1 |
| Schilling, JM | 1 |
| Kassan, A | 1 |
| Mandyam, C | 1 |
| Pearn, ML | 1 |
| Voong, A | 1 |
| Grogman, GG | 1 |
| Risbrough, VB | 1 |
| Niesman, IR | 1 |
| Patel, HH | 1 |
| Patel, PM | 1 |
| Head, BP | 1 |
| Kawano, T | 1 |
| Yamanaka, D | 1 |
| Aoyama, B | 1 |
| Tateiwa, H | 1 |
| Shigematsu-Locatelli, M | 1 |
| Nishigaki, A | 1 |
| Iwata, H | 1 |
| Locatelli, FM | 1 |
| Yokoyama, M | 1 |
| Yang, J | 6 |
| Li, M | 1 |
| Hao, J | 2 |
| Fang, X | 2 |
| Zhang, Q | 2 |
| Tang, J | 1 |
| Miller, D | 1 |
| Lewis, SR | 1 |
| Pritchard, MW | 1 |
| Schofield-Robinson, OJ | 1 |
| Shelton, CL | 1 |
| Alderson, P | 1 |
| Smith, AF | 1 |
| Yin, L | 1 |
| Bao, F | 1 |
| Wu, J | 2 |
| Li, K | 2 |
| Jiang, XL | 1 |
| Gu, XY | 1 |
| Zhou, XX | 1 |
| Chen, XM | 1 |
| Zhang, X | 3 |
| Yang, YT | 1 |
| Qin, Y | 1 |
| Shen, L | 1 |
| Yu, WF | 1 |
| Su, DS | 1 |
| Kong, F | 1 |
| Chen, S | 1 |
| Cheng, Y | 1 |
| Ma, L | 1 |
| Lu, H | 1 |
| Zhang, H | 2 |
| Hu, W | 1 |
| Liu, Y | 2 |
| Ni, C | 2 |
| Tang, Y | 1 |
| Tian, X | 1 |
| Zhou, Y | 2 |
| Qian, M | 2 |
| Li, Z | 2 |
| Chui, D | 1 |
| Guo, X | 2 |
| Li, SY | 2 |
| Chen, X | 3 |
| Chen, YL | 2 |
| Tan, L | 2 |
| Zhao, YL | 2 |
| Wang, JT | 2 |
| Xiang, Q | 1 |
| Luo, AL | 2 |
| Li, XM | 2 |
| Zhou, MT | 1 |
| Wang, XM | 1 |
| Ji, MH | 2 |
| Zhou, ZQ | 1 |
| Yang, JJ | 2 |
| Deepak, TS | 1 |
| Vadlamani, S | 1 |
| Kumar, KS | 1 |
| Kempegowda, P | 1 |
| Luo, X | 1 |
| Yang, L | 2 |
| Li, S | 3 |
| Millar, K | 1 |
| Bowman, AW | 1 |
| Burns, D | 1 |
| McLaughlin, P | 1 |
| Moores, T | 1 |
| Morton, NS | 1 |
| Musiello, T | 1 |
| Wallace, E | 1 |
| Wray, A | 1 |
| Welbury, RR | 1 |
| Ji, M | 3 |
| Dong, L | 1 |
| Jia, M | 2 |
| Liu, W | 1 |
| Zhang, M | 1 |
| Ju, L | 1 |
| Xie, Z | 5 |
| Su, F | 1 |
| Zhang, GF | 1 |
| Qiu, LL | 1 |
| Gao, J | 2 |
| Lee, BH | 1 |
| Chan, JT | 1 |
| Kraeva, E | 1 |
| Peterson, K | 1 |
| Sall, JW | 2 |
| Yang, B | 1 |
| Liang, G | 1 |
| Khojasteh, S | 1 |
| Wu, Z | 1 |
| Yang, W | 1 |
| Joseph, D | 1 |
| Wei, H | 1 |
| Li, C | 1 |
| Liu, S | 1 |
| Xing, Y | 1 |
| Tao, F | 1 |
| Liu, J | 2 |
| Wang, P | 2 |
| Zhang, W | 2 |
| Gu, G | 1 |
| Zurek, AA | 1 |
| Yu, J | 1 |
| Wang, DS | 1 |
| Haffey, SC | 1 |
| Bridgwater, EM | 1 |
| Penna, A | 1 |
| Lecker, I | 1 |
| Lei, G | 1 |
| Chang, T | 1 |
| Salter, EW | 1 |
| Orser, BA | 1 |
| Cheng, B | 1 |
| Zhang, Y | 4 |
| Wang, A | 1 |
| Dong, Y | 2 |
| Kong, FJ | 2 |
| Ma, LL | 2 |
| Zhang, HH | 1 |
| Zhou, JQ | 1 |
| Heard, C | 1 |
| Harutunians, M | 1 |
| Houck, J | 1 |
| Joshi, P | 1 |
| Johnson, K | 1 |
| Lerman, J | 1 |
| Wang, J | 1 |
| Li, Y | 1 |
| Wang, S | 2 |
| Ran, K | 1 |
| Hu, Z | 1 |
| Liu, Z | 1 |
| Duan, K | 1 |
| Acharya, NK | 1 |
| Goldwaser, EL | 1 |
| Forsberg, MM | 1 |
| Godsey, GA | 1 |
| Johnson, CA | 1 |
| Sarkar, A | 1 |
| DeMarshall, C | 1 |
| Kosciuk, MC | 1 |
| Dash, JM | 1 |
| Hale, CP | 1 |
| Leonard, DM | 1 |
| Appelt, DM | 1 |
| Nagele, RG | 1 |
| Ge, HW | 1 |
| Hu, WW | 1 |
| Li, H | 2 |
| Sun, X | 1 |
| Hao, S | 1 |
| Xia, T | 1 |
| Cui, Y | 1 |
| Chu, S | 1 |
| Song, J | 1 |
| Qian, Y | 1 |
| Ma, Z | 1 |
| Gu, X | 1 |
| Wang, W | 1 |
| Zhang, J | 1 |
| Zhao, Y | 2 |
| Luo, A | 1 |
| Zhong, T | 1 |
| Ren, F | 1 |
| Huang, CS | 1 |
| Zou, WY | 1 |
| Yang, Y | 1 |
| Pan, YD | 1 |
| Sun, B | 1 |
| Wang, E | 1 |
| Guo, QL | 1 |
| Li, D | 1 |
| Hou, D | 1 |
| Hou, J | 1 |
| Sen, T | 1 |
| Sen, N | 1 |
| Si, Y | 1 |
| Han, L | 1 |
| Xu, Y | 1 |
| Sun, F | 1 |
| Bao, H | 1 |
| Mandal, PK | 1 |
| Schifilliti, D | 1 |
| Mafrica, F | 1 |
| Fodale, V | 1 |
| Sanders, RD | 1 |
| Xu, J | 1 |
| Shu, Y | 1 |
| Januszewski, A | 1 |
| Halder, S | 1 |
| Fidalgo, A | 1 |
| Sun, P | 1 |
| Hossain, M | 1 |
| Ma, D | 1 |
| Maze, M | 1 |
| Tan, R | 1 |
| Rörtgen, D | 1 |
| Kloos, J | 1 |
| Fries, M | 2 |
| Grottke, O | 1 |
| Rex, S | 1 |
| Rossaint, R | 2 |
| Coburn, M | 1 |
| Stratmann, G | 1 |
| Bell, JS | 1 |
| Alvi, RS | 1 |
| May, Ld | 1 |
| Ku, B | 1 |
| Dowlatshahi, M | 1 |
| Dai, R | 1 |
| Bickler, PE | 1 |
| Russell, I | 1 |
| Lee, MT | 1 |
| Hrubos, MW | 1 |
| Chiu, C | 1 |
| Derwall, M | 1 |
| Timper, A | 1 |
| Kottmann, K | 1 |
| Lee, PJ | 1 |
| Wong, CS | 1 |
| Vaghadia, H | 1 |
| Jildenstål, PK | 1 |
| Hallén, JL | 1 |
| Rawal, N | 1 |
| Gupta, A | 1 |
| Berggren, L | 1 |
| Carr, ZJ | 1 |
| Torjman, MC | 1 |
| Manu, K | 1 |
| Dy, G | 1 |
| Goldberg, ME | 1 |
| Royse, CF | 3 |
| Andrews, DT | 1 |
| Newman, SN | 1 |
| Stygall, J | 1 |
| Williams, Z | 1 |
| Pang, J | 1 |
| Royse, AG | 1 |
| Bilotta, F | 1 |
| Doronzio, A | 1 |
| Stazi, E | 1 |
| Titi, L | 1 |
| Zeppa, IO | 1 |
| Cianchi, A | 1 |
| Rosa, G | 1 |
| Paoloni, FP | 1 |
| Bergese, S | 1 |
| Asouhidou, I | 1 |
| Ioannou, P | 1 |
| Abramowicz, AE | 1 |
| Spinelli, A | 1 |
| Delphin, E | 1 |
| Ayrian, E | 1 |
| Zelman, V | 1 |
| Lumb, P | 1 |
| Tang, JX | 1 |
| Mardini, F | 1 |
| Caltagarone, BM | 1 |
| Garrity, ST | 1 |
| Li, RQ | 1 |
| Bianchi, SL | 1 |
| Gomes, O | 1 |
| Laferla, FM | 1 |
| Eckenhoff, RG | 1 |
| Eckenhoff, MF | 1 |
| Lin, D | 2 |
| Zhang, B | 1 |
| Tian, M | 1 |
| Zhen, Y | 1 |
| Yue, Y | 3 |
| Sherman, J | 1 |
| Zheng, H | 1 |
| Tanzi, RE | 1 |
| Marcantonio, ER | 1 |
| Yan, XB | 1 |
| Ouyang, W | 1 |
| Li, G | 1 |
| Duan, KM | 1 |
| Cao, L | 1 |
| Wang, Z | 1 |
| Li, J | 1 |
| Washington, JM | 1 |
| Lee, S | 1 |
| Park, SH | 1 |
| Wang, H | 3 |
| Xu, Z | 2 |
| Feng, C | 1 |
| Wang, Y | 2 |
| Jia, X | 1 |
| Wu, A | 1 |
| Callaway, JK | 2 |
| Jones, NC | 2 |
| Kinoshita, H | 1 |
| Hatakeyama, N | 1 |
| Fujiwara, Y | 1 |
| Li, SZ | 1 |
| Feng, CS | 1 |
| Qu, XD | 1 |
| Zhang, XN | 1 |
| Wu, AS | 1 |
| Braunecker, S | 1 |
| Hinkelbein, J | 1 |
| Li, W | 1 |
| Zheng, B | 1 |
| Xu, H | 1 |
| Deng, Y | 1 |
| Wang, X | 1 |
| Su, D | 1 |
| Xia, LX | 1 |
| Shen, X | 1 |
| Miao, C | 1 |
| Soriano, SG | 1 |
| Sun, D | 1 |
| Baxter, MG | 1 |
| Statler, KD | 1 |
| Alexander, H | 1 |
| Vagni, V | 1 |
| Dixon, CE | 1 |
| Clark, RS | 1 |
| Jenkins, L | 1 |
| Kochanek, PM | 1 |
| Kanbak, M | 1 |
| Saricaoglu, F | 1 |
| Akinci, SB | 1 |
| Oc, B | 1 |
| Balci, H | 1 |
| Celebioglu, B | 1 |
| Aypar, U | 1 |
| Mahajan, VA | 1 |
| Ni Chonghaile, M | 1 |
| Bokhari, SA | 1 |
| Harte, BH | 1 |
| Flynn, NM | 1 |
| Laffey, JG | 1 |
| Royse, C | 1 |
| Sackey, PV | 1 |
| Martling, CR | 1 |
| Carlswärd, C | 1 |
| Sundin, O | 1 |
| Radell, PJ | 1 |
| Zacny, JP | 1 |
| Yajnik, S | 1 |
| Lichtor, JL | 1 |
| Klafta, JM | 1 |
| Young, CJ | 1 |
| Thapar, P | 1 |
| Rupani, G | 1 |
| Coalson, DW | 1 |
| Apfelbaum, JL | 1 |
| Breheny, FX | 1 |
| Kendall, PA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT02909413] | 600 participants (Anticipated) | Interventional | 2016-10-31 | Not yet recruiting | |||
| Early Cognitive Function and Recovery in Elderly Patients After Laser Laryngeal Surgery: Desflurane-based vs Propofol-based Anesthesia[NCT03194074] | Phase 4 | 70 participants (Anticipated) | Interventional | 2017-08-15 | Recruiting | ||
| Post Operative Cognitive Recovery and Neuropsychological Complications After General Anesthesia. A Comparison Between Different Techniques of Anesthesia: A Multi-Center Observational Study[NCT00507195] | 1,200 participants (Anticipated) | Observational | 2007-05-31 | Recruiting | |||
| Could Music be an Alternative to Sedation in Patients Treated Total Knee Arthroplasty With Regional Anesthesia?: A Randomized Clinical Trial[NCT03882541] | 85 participants (Actual) | Interventional | 2017-01-08 | Completed | |||
| Prospective Randomised Controled Trial: Comparison of Volatile Anaesthetics Sevoflurane vs. Isoflurane for Low-Flow General Anaesthesia for Abdominal Surgery[NCT00521612] | 82 participants (Actual) | Interventional | 2007-09-30 | Completed | |||
| Evaluation of Mirus™ for Sedation in Resuscitation[NCT02889055] | 9 participants (Actual) | Observational | 2016-01-17 | Terminated (stopped due to Safety profile was not satisfying with sevolflurane) | |||
| A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05327296] | Phase 3 | 235 participants (Anticipated) | Interventional | 2022-06-30 | Recruiting | ||
| A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05312385] | Phase 3 | 235 participants (Anticipated) | Interventional | 2022-04-28 | Recruiting | ||
| Effects of Subanesthetic Concentrations of Isoflurane/Nitrous Oxide[NCT00000251] | Phase 2 | 10 participants (Actual) | Interventional | 1994-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for isoflurane and Cognition Disorders
| Article | Year |
|---|---|
Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave | 2018 |
Inhaled anesthesia and cognitive performance.
Topics: Age Factors; Aged; Anesthetics, Inhalation; Cognition Disorders; Desflurane; Humans; Isoflurane; Met | 2009 |
13 trials available for isoflurane and Cognition Disorders
| Article | Year |
|---|---|
Post-operative cognitive functions after general anesthesia with sevoflurane and desflurane in South Asian elderly.
Topics: Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; C | 2013 |
Children's cognitive recovery after day-case general anesthesia: a randomized trial of propofol or isoflurane for dental procedures.
Topics: Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Anesthesia, Inhalation; Ane | 2014 |
Propofol anesthesia for children undergoing magnetic resonance imaging: a comparison with isoflurane, nitrous oxide, and a laryngeal mask airway.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Asthma; Child; Child, Preschool; Cognition Disord | 2015 |
[Effect of propofol and isoflurane on surgical stress response and postoperative cognitive function in elderly patients].
Topics: Abdomen; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, | 2009 |
Comparison of early cognitive function and recovery after desflurane or sevoflurane anaesthesia in the elderly: a double-blinded randomized controlled trial.
Topics: Aged; Anesthesia Recovery Period; Anesthetics, Inhalation; Cognition Disorders; Desflurane; Double-B | 2010 |
Effect of auditory evoked potential-guided anaesthesia on consumption of anaesthetics and early postoperative cognitive dysfunction: a randomised controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Anesthesia, General; Anesthetics, General; C | 2011 |
The influence of propofol or desflurane on postoperative cognitive dysfunction in patients undergoing coronary artery bypass surgery.
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Cognition; Cognition Disorders; Coronary Ar | 2011 |
Early postoperative cognitive dysfunction and postoperative delirium after anaesthesia with various hypnotics: study protocol for a randomised controlled trial--the PINOCCHIO trial.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Cognition; Cognition Disorde | 2011 |
The effects of isoflurane and desflurane on cognitive function in humans.
Topics: Aged; Analysis of Variance; Anesthesia, Spinal; Anesthetics, Inhalation; Boston; China; Cognition; C | 2012 |
The effects of isoflurane, sevoflurane, and desflurane anesthesia on neurocognitive outcome after cardiac surgery: a pilot study.
Topics: Anesthesia, Inhalation; Biomarkers; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cognition D | 2007 |
Recovery of older patients undergoing ambulatory anaesthesia with isoflurane or sevoflurane.
Topics: Aged; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; Anesthetics, Inh | 2007 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
The acute and residual effects of subanesthetic concentrations of isoflurane/nitrous oxide combinations on cognitive and psychomotor performance in healthy volunteers.
Topics: Adult; Anesthetics, Inhalation; Cognition; Cognition Disorders; Cross-Over Studies; Dose-Response Re | 1996 |
55 other studies available for isoflurane and Cognition Disorders
| Article | Year |
|---|---|
Toll-like receptor 2 activation and up-regulation by high mobility group box-1 contribute to post-operative neuroinflammation and cognitive dysfunction in mice.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Behavior, Animal; Benzocycloheptenes; Cognition Disord | 2021 |
Apigenin attenuates isoflurane-induced cognitive dysfunction via epigenetic regulation and neuroinflammation in aged rats.
Topics: Acetylation; Animals; Apigenin; Cognition; Cognition Disorders; Cognitive Dysfunction; Epigenesis, G | 2017 |
Inhibition of p75 neurotrophin receptor does not rescue cognitive impairment in adulthood after isoflurane exposure in neonatal mice.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cognition Disorders; Disease Models, Animal; Fem | 2017 |
Involvement of acute neuroinflammation in postoperative delirium-like cognitive deficits in rats.
Topics: Animals; Brain; Cognition; Cognition Disorders; Cognitive Dysfunction; Cytokines; Delirium; Fear; Hi | 2018 |
[Acute injury to ce.rebral function produced by isoflurane anesthesia given at different time interval in neonatal rats]
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Animals, Newborn; Brain Injuries; Cognition Disorders; | 2016 |
NLRP3 inflammasome-dependent pyroptosis is proposed to be involved in the mechanism of age-dependent isoflurane-induced cognitive impairment.
Topics: Aging; Anesthetics, Inhalation; Cognition Disorders; Cytokines; Humans; Isoflurane; NLR Family, Pyri | 2018 |
Intestinal dysbacteriosis mediates the reference memory deficit induced by anaesthesia/surgery in aged mice.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cognition; Cognition Disorders; Dysbiosis; Gastrointes | 2019 |
Minocycline attenuates cognitive impairment induced by isoflurane anesthesia in aged rats.
Topics: Aging; Anesthesia; Animals; Apoptosis; Arterial Pressure; CA1 Region, Hippocampal; Caspase 3; Cognit | 2013 |
Melatonin attenuates isoflurane-induced acute memory impairments in aged rats.
Topics: Animals; Cognition Disorders; Hippocampus; Isoflurane; Male; Maze Learning; Melatonin; Memory; Memor | 2013 |
Role of GSK-3β in isoflurane-induced neuroinflammation and cognitive dysfunction in aged rats.
Topics: Animals; Cognition Disorders; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Inflammat | 2013 |
Resveratrol pretreatment attenuates the isoflurane-induced cognitive impairment through its anti-inflammation and -apoptosis actions in aged mice.
Topics: Age Factors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Apoptosis Regulatory Prote | 2014 |
Tau hyperphosphorylation: a downstream effector of isoflurane-induced neuroinflammation in aged rodents.
Topics: Age Factors; Alzheimer Disease; Anesthetics, Inhalation; Animals; Cognition Disorders; Cytokines; In | 2014 |
Epigenetic enhancement of brain-derived neurotrophic factor signaling pathway improves cognitive impairments induced by isoflurane exposure in aged rats.
Topics: Aging; Animals; Association Learning; Brain-Derived Neurotrophic Factor; Cognition Disorders; Condit | 2014 |
Disruption of hippocampal neuregulin 1-ErbB4 signaling contributes to the hippocampus-dependent cognitive impairment induced by isoflurane in aged mice.
Topics: Aging; Anesthetics, Inhalation; Animals; Blotting, Western; Cognition Disorders; Down-Regulation; En | 2014 |
Isoflurane exposure in newborn rats induces long-term cognitive dysfunction in males but not females.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Behavior, Animal; Brain; Cell Death; Cognition D | 2014 |
Comparison of neurodegeneration and cognitive impairment in neonatal mice exposed to propofol or isoflurane.
Topics: Administration, Inhalation; Anesthetics; Animals; Animals, Newborn; Apoptosis; Brain Damage, Chronic | 2014 |
The role of hippocampal tau protein phosphorylation in isoflurane-induced cognitive dysfunction in transgenic APP695 mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Cognition; Cognition D | 2014 |
Effects of different concentration and duration time of isoflurane on acute and long-term neurocognitive function of young adult C57BL/6 mouse.
Topics: Administration, Inhalation; Age Factors; Anesthetics, Inhalation; Animals; Apoptosis; Behavior, Anim | 2014 |
Sustained increase in α5GABAA receptor function impairs memory after anesthesia.
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Cognition Disorders; Disease Models, Animal; | 2014 |
Vitamin C Attenuates Isoflurane-Induced Caspase-3 Activation and Cognitive Impairment.
Topics: Adenosine Triphosphate; Animals; Ascorbic Acid; Caspase 3; Cell Line, Tumor; Cognition Disorders; Hu | 2015 |
Alpha 7 nicotinic acetylcholine receptor agonist GTS-21 mitigates isoflurane-induced cognitive impairment in aged rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Benzylidene Compounds; Cognition Disorders; Hippocampus | 2015 |
Isoflurane induced cognitive impairment in aged rats through hippocampal calcineurin/NFAT signaling.
Topics: Aging; Animals; Calcineurin; Cognition Disorders; Hippocampus; Isoflurane; Male; NFATC Transcription | 2015 |
Differential hippocampal protein expression between normal aged rats and aged rats with postoperative cognitive dysfunction: A proteomic analysis.
Topics: Anesthetics, Inhalation; Animals; Cognition; Cognition Disorders; Electrophoresis, Gel, Two-Dimensio | 2015 |
Sevoflurane and Isoflurane induce structural changes in brain vascular endothelial cells and increase blood-brain barrier permeability: Possible link to postoperative delirium and cognitive decline.
Topics: Aging; Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Capillary Permeability; Cognition Diso | 2015 |
Endoplasmic reticulum stress pathway mediates isoflurane-induced neuroapoptosis and cognitive impairments in aged rats.
Topics: Activating Transcription Factors; Aging; Anesthetics, Inhalation; Animals; Apoptosis; Cognition Diso | 2015 |
A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice.
Topics: Adenosine Triphosphate; Aging; Anesthetics, Inhalation; Animals; Antioxidants; Cognition Disorders; | 2015 |
Melatonin pretreatment prevents isoflurane-induced cognitive dysfunction by modulating sleep-wake rhythm in mice.
Topics: Animals; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Isoflurane; Male; Melaton | 2016 |
Glycyrrhizin attenuates isoflurane-induced cognitive deficits in neonatal rats via its anti-inflammatory activity.
Topics: Anesthetics; Animals; Animals, Newborn; Anti-Inflammatory Agents; Apoptosis; Cognition Disorders; Di | 2016 |
Swimming exercise ameliorates neurocognitive impairment induced by neonatal exposure to isoflurane and enhances hippocampal histone acetylation in mice.
Topics: Acetylation; Anesthetics; Animals; Animals, Newborn; Blood Glucose; Cognition Disorders; Disease Mod | 2016 |
Taurine Pretreatment Prevents Isoflurane-Induced Cognitive Impairment by Inhibiting ER Stress-Mediated Activation of Apoptosis Pathways in the Hippocampus in Aged Rats.
Topics: Aging; Animals; Apoptosis; Brain; Cognition Disorders; Endoplasmic Reticulum Stress; Hippocampus; Is | 2016 |
Isoflurane-induced inactivation of CREB through histone deacetylase 4 is responsible for cognitive impairment in developing brain.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Brain; Cognition Disorders; CREB-Binding Protein | 2016 |
Dexmedetomidine Acts via the JAK2/STAT3 Pathway to Attenuate Isoflurane-Induced Neurocognitive Deficits in Senile Mice.
Topics: Animals; Cognition Disorders; Dexmedetomidine; Isoflurane; Janus Kinase 2; Mice; STAT3 Transcription | 2016 |
Neonatal Repeated Exposure to Isoflurane not Sevoflurane in Mice Reversibly Impaired Spatial Cognition at Juvenile-Age.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cognition Disorders; Isoflurane; Male; Maze Lear | 2017 |
Dexmedetomidine attenuates isoflurane-induced neurocognitive impairment in neonatal rats.
Topics: Animals; Animals, Newborn; Apoptosis; Cognition Disorders; Dexmedetomidine; Isoflurane; Mice; Mice, | 2009 |
Isoflurane does not affect brain cell death, hippocampal neurogenesis, or long-term neurocognitive outcome in aged rats.
Topics: Aging; Algorithms; Anesthetics, Inhalation; Animals; Brain; Cell Death; Cell Differentiation; Cell P | 2010 |
Neuroprotective effects of the inhalational anesthetics isoflurane and xenon after cardiac arrest in pigs.
Topics: Anesthetics, Inhalation; Animals; Cardiac Output; Cardiopulmonary Resuscitation; Cognition Disorders | 2008 |
Baseline bispectral index values below 46 in an octogenarian under desflurane anesthesia.
Topics: Aged, 80 and over; Algorithms; Anesthetics, Inhalation; Cholecystectomy, Laparoscopic; Cholecystitis | 2010 |
Spatial memory using active allothetic place avoidance in adult rats after isoflurane anesthesia: a potential model for postoperative cognitive dysfunction.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Avoidance Learning; Cognition Disorders; D | 2011 |
Anesthesia in presymptomatic Alzheimer's disease: a study using the triple-transgenic mouse model.
Topics: Alzheimer Disease; Anesthetics, Inhalation; Animals; Brain; Cognition Disorders; Disease Models, Ani | 2011 |
Isoflurane induces hippocampal cell injury and cognitive impairments in adult rats.
Topics: Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Caspase 3; Cognition Disorders; Conditionin | 2011 |
Involvement of neuronal nitric oxide synthase in cognitive impairment in isoflurane-treated rats.
Topics: Anesthetics, Inhalation; Animals; Cognition Disorders; Female; Hippocampus; Immunohistochemistry; Is | 2012 |
Lidocaine attenuates cognitive impairment after isoflurane anesthesia in old rats.
Topics: Aging; Amyloid beta-Peptides; Anesthetics, Inhalation; Anesthetics, Local; Animals; Brain; Cognition | 2012 |
Effects of isoflurane on learning and memory functions of wild-type and glutamate transporter type 3 knockout mice.
Topics: Anesthetics, Inhalation; Animals; Brain Chemistry; Cognition Disorders; Excitatory Amino Acid Transp | 2012 |
Changes of learning and memory in aged rats after isoflurane inhalational anaesthesia correlated with hippocampal acetylcholine level.
Topics: Acetylcholine; Aging; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Brain; Brain Chemi | 2012 |
Isoflurane induces cognitive deficits in the Morris water maze task in rats.
Topics: Age Factors; Anesthetics, Inhalation; Animals; Behavior, Animal; Cognition; Cognition Disorders; Iso | 2012 |
Postoperative cognitive deficit might relate to intraoperative hypotension.
Topics: Anesthetics, Inhalation; Cognition; Cognition Disorders; Female; Humans; Isoflurane; Male | 2012 |
Serum proteomics of early postoperative cognitive dysfunction in elderly patients.
Topics: Aged; Anesthesia, Inhalation; Arthroplasty; Cognition Disorders; Female; Humans; Isoflurane; Male; M | 2012 |
Isoflurane is not necessarily the only cause of cognitive deficits.
Topics: Anesthetics, Inhalation; Animals; Behavior, Animal; Cognition; Cognition Disorders; Isoflurane; Male | 2013 |
Reply to: Isoflurane is not necessarily the only cause of cognitive deficits.
Topics: Anesthetics, Inhalation; Animals; Behavior, Animal; Cognition; Cognition Disorders; Isoflurane; Male | 2013 |
Isoflurane prevents neurocognitive dysfunction after cardiopulmonary bypass in rats.
Topics: Acetylcholine; Acetylcholinesterase; Anesthetics, Inhalation; Animals; Behavior, Animal; Bicarbonate | 2013 |
Minocycline mitigates isoflurane-induced cognitive impairment in aged rats.
Topics: Aging; Anesthetics, Inhalation; Animals; bcl-2-Associated X Protein; Caspase 3; Cells, Cultured; Cog | 2013 |
Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment.
Topics: Age Factors; Anesthetics, Inhalation; Animals; Brain; Cognition Disorders; Desflurane; Drug Therapy, | 2013 |
Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats.
Topics: Anesthetics; Animals; Brain; Brain Injuries; Cell Survival; Cognition Disorders; Diazepam; Disease M | 2006 |
Is depth of anesthesia, as assessed by the bispectral index, related to postoperative cognitive dysfunction and recovery?
Topics: Anesthesia; Anesthesia Recovery Period; Cognition Disorders; Electroencephalography; Humans; Isoflur | 2007 |
Use of isoflurane for sedation in intensive care.
Topics: Acute Kidney Injury; Cognition Disorders; Fenthion; Humans; Hypnotics and Sedatives; Isoflurane; Leg | 1992 |