Page last updated: 2024-10-29

isoflurane and Brain Injuries

isoflurane has been researched along with Brain Injuries in 40 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.

Research Excerpts

ExcerptRelevanceReference
"The effects of induced hypotension with isoflurane and labetalol on cerebral edema formation were compared following a cryogenic brain injury in dogs."9.07Cerebral edema formation in dogs following hypotension induced with isoflurane and labetalol. ( Bendo, AA; Capuano, C; Cottrell, JE; Kozlowski, PB; Mendeszoon, MH, 1993)
"To investigate effects of isoflurane anesthesia of different time interval on acute injury of brain function in neonatal rats with consistent total time of isoflurane anesthesia."7.83[Acute injury to ce.rebral function produced by isoflurane anesthesia given at different time interval in neonatal rats] ( Fang, X; Hao, J; Li, M; Tang, J; Yang, J; Zhang, Q, 2016)
"Isoflurane significantly improved neurobehavioral function and brain edema at 24 hrs but not 72 hrs after subarachnoid hemorrhage."7.78Isoflurane delays the development of early brain injury after subarachnoid hemorrhage through sphingosine-related pathway activation in mice. ( Altay, O; Hasegawa, Y; Khatibi, NH; Sherchan, P; Suzuki, H; Tang, J; Zhang, JH, 2012)
"Despite common use of narcotics in the clinical management of severe traumatic brain injury (TBI), in experimental models rats treated with fentanyl have exhibited worse functional outcome and more CA1 hippocampal death than rats treated with standard isoflurane anesthesia."7.72Hyperglycolysis is exacerbated after traumatic brain injury with fentanyl vs. isoflurane anesthesia in rats. ( Clark, RS; Janesko, KL; Jenkins, LW; Kochanek, PM; Melick, JA; Statler, KD, 2003)
"To evaluate the impact of anesthetics on the evolution of a cerebral injury, 33 rabbits were subjected to a cryogenic brain lesion, followed by 10 h of anesthesia with 1 MAC halothane or isoflurane (n = 11 each) or with an equipotent dose of pentobarbital (n = 11)."7.67A comparison of the effects of halothane, isoflurane, and pentobarbital anesthesia on intracranial pressure and cerebral edema formation following brain injury in rabbits. ( Kaieda, R; Todd, MM; Warner, DS; Weeks, JB, 1989)
"Using a middle cerebral artery occlusion (MCAO) model, triphenyltetrazolium chloride staining was utilized to measure the infarct volume and brain edema and immunofluorescence staining was used to detect the MCAO-induced TLR4 expression and localization."5.42Protective role of isoflurane pretreatment in rats with focal cerebral ischemia and the underlying molecular mechanism. ( Chao, Y; Chen, L; Gao, C; Kuai, J; Lv, M; Ren, P; Sun, X; Wang, Q; Xiao, Z, 2015)
" Transient MCAO was induced during either isoflurane or ketamine/xylazine (ket/xyl) anesthesia with simultaneously measurement of cerebral blood flow (CBF) in 60 male Wistar rats (380-420 g)."5.17Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model. ( Bleilevens, C; Dang, J; Goetzenich, A; Hein, M; Kipp, M; Roehl, AB; Rossaint, R; Tolba, R; Zoremba, N, 2013)
"The effects of induced hypotension with isoflurane and labetalol on cerebral edema formation were compared following a cryogenic brain injury in dogs."5.07Cerebral edema formation in dogs following hypotension induced with isoflurane and labetalol. ( Bendo, AA; Capuano, C; Cottrell, JE; Kozlowski, PB; Mendeszoon, MH, 1993)
"To investigate effects of isoflurane anesthesia of different time interval on acute injury of brain function in neonatal rats with consistent total time of isoflurane anesthesia."3.83[Acute injury to ce.rebral function produced by isoflurane anesthesia given at different time interval in neonatal rats] ( Fang, X; Hao, J; Li, M; Tang, J; Yang, J; Zhang, Q, 2016)
"Isoflurane significantly improved neurobehavioral function and brain edema at 24 hrs but not 72 hrs after subarachnoid hemorrhage."3.78Isoflurane delays the development of early brain injury after subarachnoid hemorrhage through sphingosine-related pathway activation in mice. ( Altay, O; Hasegawa, Y; Khatibi, NH; Sherchan, P; Suzuki, H; Tang, J; Zhang, JH, 2012)
"Despite common use of narcotics in the clinical management of severe traumatic brain injury (TBI), in experimental models rats treated with fentanyl have exhibited worse functional outcome and more CA1 hippocampal death than rats treated with standard isoflurane anesthesia."3.72Hyperglycolysis is exacerbated after traumatic brain injury with fentanyl vs. isoflurane anesthesia in rats. ( Clark, RS; Janesko, KL; Jenkins, LW; Kochanek, PM; Melick, JA; Statler, KD, 2003)
"To evaluate the impact of anesthetics on the evolution of a cerebral injury, 33 rabbits were subjected to a cryogenic brain lesion, followed by 10 h of anesthesia with 1 MAC halothane or isoflurane (n = 11 each) or with an equipotent dose of pentobarbital (n = 11)."3.67A comparison of the effects of halothane, isoflurane, and pentobarbital anesthesia on intracranial pressure and cerebral edema formation following brain injury in rabbits. ( Kaieda, R; Todd, MM; Warner, DS; Weeks, JB, 1989)
"Traumatic brain injuries remain an area of great challenge to both neurosurgeons and neuroanaesthesiologists."2.45Traumatic brain injury: neuroprotective anaesthetic techniques, an update. ( Aal-Shaya, WA; Al-Faridi, K; Halawani, MM; Taha, WS; Tawfeeq, NA, 2009)
"Using a middle cerebral artery occlusion (MCAO) model, triphenyltetrazolium chloride staining was utilized to measure the infarct volume and brain edema and immunofluorescence staining was used to detect the MCAO-induced TLR4 expression and localization."1.42Protective role of isoflurane pretreatment in rats with focal cerebral ischemia and the underlying molecular mechanism. ( Chao, Y; Chen, L; Gao, C; Kuai, J; Lv, M; Ren, P; Sun, X; Wang, Q; Xiao, Z, 2015)
"Rats treated with isoflurane had the best cognitive recovery (p < 0."1.33Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats. ( Alexander, H; Clark, RS; Dixon, CE; Jenkins, L; Kochanek, PM; Statler, KD; Vagni, V, 2006)
"Fentanyl-treated rats had higher mean arterial blood pressure after injury (p < 0."1.31Isoflurane improves long-term neurologic outcome versus fentanyl after traumatic brain injury in rats. ( Alexander, HL; Clark, RS; Dixon, CE; Graham, SH; Jenkins, LW; Kochanek, PM; Marion, DW; Safar, PJ; Statler, KD; Warner, DS; Wisniewski, SR, 2000)
"In patients with hydrocephalus occlusus a biphasic course of the intracranial pressure was frequently observed."1.27[Effect of isoflurane on intracranial pressure]. ( Limberg, NJ; Oehmen, S; Pfeifer, G; Schultheiss, R, 1987)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.00)18.7374
1990's8 (20.00)18.2507
2000's11 (27.50)29.6817
2010's15 (37.50)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Li, N1
Zhang, X1
Zhai, J1
Yin, J1
Ma, K1
Wang, R1
Qin, X1
Li, Y1
Dong, X1
Wang, S1
Tian, LY1
Cai, CK1
Zhang, XJ1
Sun, XD1
Cheon, SY1
Kim, SY1
Kam, EH1
Lee, JH1
Kim, JM1
Kim, EJ1
Kim, TW1
Koo, BN1
Kang, F1
Tang, C1
Han, M1
Chai, X1
Huang, X1
Li, J1
Yang, J1
Li, M1
Hao, J2
Fang, X1
Zhang, Q1
Tang, J2
Hertle, D2
Werhahn, L1
Beynon, C2
Zweckberger, K2
Vienenkötter, B2
Jung, CS2
Unterberg, A2
Kiening, K2
Sakowitz, O1
Xiao, Z1
Ren, P1
Chao, Y1
Wang, Q1
Kuai, J1
Lv, M1
Chen, L1
Gao, C1
Sun, X1
Wang, CM1
Cai, XL1
Wen, QP1
Mutoh, T2
Sasaki, K1
Yamamoto, Y1
Tsuru, Y1
Tsubone, H1
Ishikawa, T1
Taki, Y1
Gökçek, E1
Kaydu, A1
Akdemir, MS1
Akil, F1
Akıncı, IO1
Tawfeeq, NA1
Halawani, MM1
Al-Faridi, K1
Aal-Shaya, WA1
Taha, WS1
Dabrowski, W1
Rzecki, Z1
Czajkowski, M1
Pilat, J1
Wacinski, P1
Kotlinska, E1
Sztanke, M1
Sztanke, K1
Stazka, K1
Pasternak, K1
Sakowitz, OW2
Altay, O1
Hasegawa, Y1
Sherchan, P1
Suzuki, H1
Khatibi, NH1
Zhang, JH1
Klugmann, M1
Villa, F1
Citerio, G1
Bleilevens, C1
Roehl, AB1
Goetzenich, A1
Zoremba, N1
Kipp, M1
Dang, J1
Tolba, R1
Rossaint, R1
Hein, M1
Thal, SC1
Luh, C1
Schaible, EV1
Timaru-Kast, R1
Hedrich, J1
Luhmann, HJ1
Engelhard, K1
Zehendner, CM1
Statler, KD4
Janesko, KL1
Melick, JA1
Clark, RS4
Jenkins, LW2
Kochanek, PM4
Stover, JF1
Kroppenstedt, SN1
Thomale, UW1
Kempski, OS1
Flügge, G1
Unterberg, AW1
Zhao, P1
Zuo, Z1
Alexander, H2
Vagni, V2
Dixon, CE3
Jenkins, L2
Holubkov, R1
Miller, P1
Mack, CD1
Sammer, M1
Rozet, I1
Lee, LA1
Muangman, S1
Wang, M1
Hollingworth, W1
Lam, AM1
Vavilala, MS1
Luckl, J1
Keating, J1
Greenberg, JH1
Sun, H1
Zhao, H1
Sharpe, GM1
Arrick, DM1
Mayhan, WG1
Adams, RW1
Cucchiara, RF1
Gronert, GA1
Messick, JM1
Michenfelder, JD1
Murr, R3
Berger, S3
Schürer, L3
Peter, K3
Baethmann, A3
Koenig, HM1
Enzenbach, R2
Bendo, AA1
Kozlowski, PB1
Capuano, C1
Cottrell, JE1
Mendeszoon, MH1
Ornstein, E1
Young, WL1
Fleischer, LH1
Ostapkovich, N1
Alexander, HL1
Warner, DS3
Wisniewski, SR1
Graham, SH1
Marion, DW1
Safar, PJ1
Kahveci, FS1
Kahveci, N1
Alkan, T1
Goren, B1
Korfali, E1
Ozluk, K1
Ramani, R1
Todd, MM3
Archer, DP1
Elphinstone, MG1
Pappius, HM1
Kaieda, R1
Weeks, JB1
Scheller, MS1
Drummond, JC1
Zornow, MH1
Pfeifer, G1
Oehmen, S1
Limberg, NJ1
Schultheiss, R1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Inhalatorial Sedation in Patient With SAH Versus Conventional Intravenous Sedation (GAS-SAH)[NCT00830843]Phase 413 participants (Actual)Interventional2009-01-31Completed
Effect of Dexmedetomidine of Gastrointestinal Motility[NCT04798482]Phase 422 participants (Actual)Interventional2021-09-14Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for isoflurane and Brain Injuries

ArticleYear
Traumatic brain injury: neuroprotective anaesthetic techniques, an update.
    Injury, 2009, Volume: 40 Suppl 4

    Topics: Adolescent; Adult; Brain Injuries; Cell Death; Central Nervous System Depressants; Craniocerebral Tr

2009

Trials

6 trials available for isoflurane and Brain Injuries

ArticleYear
Effects of Dexmedetomidine-Isoflurane versus Isoflurane Anesthesia on Brain Injury After Cardiac Valve Replacement Surgery.
    Journal of cardiothoracic and vascular anesthesia, 2018, Volume: 32, Issue:4

    Topics: Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Brain Injuries; Dexmedetomidine; Drug Therapy

2018
Early postoperative recovery after intracranial surgical procedures. Comparison of the effects of sevoflurane and desflurane.
    Acta cirurgica brasileira, 2016, Volume: 31, Issue:9

    Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthetics, Inhalation; Brain Injuries; Cranio

2016
Volatile anesthetics reduce biochemical markers of brain injury and brain magnesium disorders in patients undergoing coronary artery bypass graft surgery.
    Journal of cardiothoracic and vascular anesthesia, 2012, Volume: 26, Issue:3

    Topics: Aged; Anesthetics, Inhalation; Biomarkers; Brain; Brain Injuries; Coronary Artery Bypass; Female; Gl

2012
Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model.
    Experimental brain research, 2013, Volume: 224, Issue:2

    Topics: Anesthesia; Anesthetics; Animals; Blood Pressure; Brain Edema; Brain Injuries; Cerebral Infarction;

2013
Cerebral edema formation in dogs following hypotension induced with isoflurane and labetalol.
    Acta anaesthesiologica Belgica, 1993, Volume: 44, Issue:3

    Topics: Animals; Brain; Brain Edema; Brain Injuries; Dogs; Hypotension; Isoflurane; Labetalol; Male

1993
Desflurane and isoflurane have similar effects on cerebral blood flow in patients with intracranial mass lesions.
    Anesthesiology, 1993, Volume: 79, Issue:3

    Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics; Brain Injuries; Cerebrovascular Circulation; Cran

1993

Other Studies

33 other studies available for isoflurane and Brain Injuries

ArticleYear
Isoflurane and Netrin-1 combination therapy enhances angiogenesis and neurological recovery by improving the expression of HIF-1α-Netrin-1-UNC5B/VEGF cascade to attenuate cerebral ischemia injury.
    Experimental neurology, 2022, Volume: 352

    Topics: Animals; Brain Injuries; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Hypoxia-Induci

2022
Isoflurane preconditioning effects on brain damage induced by electromagnetic pulse radiation through epigenetic modification of BDNF gene transcription.
    Annals of palliative medicine, 2020, Volume: 9, Issue:5

    Topics: Animals; Brain; Brain Injuries; Brain-Derived Neurotrophic Factor; Electromagnetic Phenomena; Epigen

2020
Isoflurane preconditioning inhibits the effects of tissue-type plasminogen activator on brain endothelial cell in an
    International journal of medical sciences, 2017, Volume: 14, Issue:5

    Topics: Animals; Apoptosis; Brain Injuries; Brain Ischemia; Culture Media, Conditioned; Cyclooxygenase 2; Di

2017
[Acute injury to ce.rebral function produced by isoflurane anesthesia given at different time interval in neonatal rats]
    Zhonghua wei zhong bing ji jiu yi xue, 2016, Volume: 28, Issue:3

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Animals, Newborn; Brain Injuries; Cognition Disorders;

2016
Depression of neuronal activity by sedatives is associated with adverse effects after brain injury.
    Brain research, 2013, May-13, Volume: 1510

    Topics: Analysis of Variance; Animals; Brain Injuries; Disease Models, Animal; Electroencephalography; Hypno

2013
Protective role of isoflurane pretreatment in rats with focal cerebral ischemia and the underlying molecular mechanism.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: Animals; Astrocytes; Brain Injuries; Brain Ischemia; Disease Models, Animal; Humans; Infarction, Mid

2015
Astaxanthin reduces isoflurane-induced neuroapoptosis via the PI3K/Akt pathway.
    Molecular medicine reports, 2016, Volume: 13, Issue:5

    Topics: Animals; Apoptosis; Brain Injuries; Isoflurane; Male; Phosphatidylinositol 3-Kinases; Proto-Oncogene

2016
Isoflurane postconditioning with cardiac support promotes recovery from early brain injury in mice after severe subarachnoid hemorrhage.
    Life sciences, 2016, May-15, Volume: 153

    Topics: Animals; Brain Injuries; Dobutamine; Heart; Hemodynamics; Isoflurane; Male; Mice; Mice, Inbred C57BL

2016
Influence of isoflurane on neuronal death and outcome in a rat model of traumatic brain injury.
    Acta neurochirurgica. Supplement, 2012, Volume: 114

    Topics: Anesthetics, Inhalation; Animals; Apoptosis; Brain Injuries; Disease Models, Animal; In Situ Nick-En

2012
Isoflurane delays the development of early brain injury after subarachnoid hemorrhage through sphingosine-related pathway activation in mice.
    Critical care medicine, 2012, Volume: 40, Issue:6

    Topics: Animals; Apoptosis; Brain Edema; Brain Injuries; Isoflurane; Lysophospholipids; Male; Mice; Neuropro

2012
Volatile meets versatile: does isoflurane strike a new path to neuroprotection?
    Critical care medicine, 2012, Volume: 40, Issue:6

    Topics: Animals; Apoptosis; Brain Injuries; Isoflurane; Male; Neuroprotective Agents; Subarachnoid Hemorrhag

2012
Surpassing boundaries: volatile sedation in the NeuroICU.
    Intensive care medicine, 2012, Volume: 38, Issue:12

    Topics: Adult; Anesthetics, Inhalation; Animals; Brain Injuries; Cerebrovascular Circulation; Humans; Hypnot

2012
Volatile anesthetics influence blood-brain barrier integrity by modulation of tight junction protein expression in traumatic brain injury.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cell Line; Claud

2012
Hyperglycolysis is exacerbated after traumatic brain injury with fentanyl vs. isoflurane anesthesia in rats.
    Brain research, 2003, Dec-19, Volume: 994, Issue:1

    Topics: Anesthesia; Animals; Brain Injuries; Fentanyl; Glucose; Glycolysis; Isoflurane; Male; Rats; Rats, Sp

2003
Differential effects of prolonged isoflurane anesthesia on plasma, extracellular, and CSF glutamate, neuronal activity, 125I-Mk801 NMDA receptor binding, and brain edema in traumatic brain-injured rats.
    Acta neurochirurgica, 2004, Volume: 146, Issue:8

    Topics: Anesthetics, Inhalation; Animals; Body Water; Brain; Brain Injuries; Dizocilpine Maleate; Drug Admin

2004
Isoflurane preconditioning induces neuroprotection that is inducible nitric oxide synthase-dependent in neonatal rats.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Blood Gas Analysis; Blotting, Western; Body Weig

2004
Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats.
    Journal of neurotrauma, 2006, Volume: 23, Issue:1

    Topics: Anesthetics; Animals; Brain; Brain Injuries; Cell Survival; Cognition Disorders; Diazepam; Disease M

2006
Isoflurane exerts neuroprotective actions at or near the time of severe traumatic brain injury.
    Brain research, 2006, Mar-03, Volume: 1076, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Behavior, Animal; Blood Pressure; Brain Injuries; Cell Count; Dis

2006
The incidence and risk factors for hypotension during emergent decompressive craniotomy in children with traumatic brain injury.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:4

    Topics: Age Factors; Anesthesia, General; Brain Injuries; Child, Preschool; Craniotomy; Female; Fentanyl; Hu

2006
Alpha-chloralose is a suitable anesthetic for chronic focal cerebral ischemia studies in the rat: a comparative study.
    Brain research, 2008, Jan-29, Volume: 1191

    Topics: Anesthesia; Anesthetics, Intravenous; Animals; Brain; Brain Injuries; Brain Ischemia; Cerebrovascula

2008
Effect of chronic alcohol consumption on brain damage following transient focal ischemia.
    Brain research, 2008, Feb-15, Volume: 1194

    Topics: Alcohol Drinking; Analgesics; Analysis of Variance; Animals; Body Weight; Brain Injuries; Cerebral A

2008
Isoflurane and cerebrospinal fluid pressure in neurosurgical patients.
    Anesthesiology, 1981, Volume: 54, Issue:2

    Topics: Adult; Anesthesia, Inhalation; Brain Injuries; Brain Neoplasms; Carbon Dioxide; Craniotomy; Hematoma

1981
Influence of isoflurane, fentanyl, thiopental, and alpha-chloralose on formation of brain edema resulting from a focal cryogenic lesion.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:6

    Topics: Anesthetics; Animals; Brain; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Chloralose; F

1995
What's up with the new volatile anesthetics, desflurane and sevoflurane, for neurosurgical patients?
    Journal of neurosurgical anesthesiology, 1994, Volume: 6, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Blood Volume; Brain; Brain Injuries; Carbon Dioxide; Cerebrospinal

1994
Effects of isoflurane, fentanyl, or thiopental anesthesia on regional cerebral blood flow and brain surface PO2 in the presence of a focal lesion in rabbits.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:5

    Topics: Anesthetics; Animals; Brain Injuries; Cerebrovascular Circulation; Fentanyl; Isoflurane; Oxygen; Par

1993
Isoflurane improves long-term neurologic outcome versus fentanyl after traumatic brain injury in rats.
    Journal of neurotrauma, 2000, Volume: 17, Issue:12

    Topics: Analgesics, Opioid; Animals; Brain Injuries; Fentanyl; Intracranial Pressure; Isoflurane; Male; Nerv

2000
Propofol versus isoflurane anesthesia under hypothermic conditions: effects on intracranial pressure and local cerebral blood flow after diffuse traumatic brain injury in the rat.
    Surgical neurology, 2001, Volume: 56, Issue:3

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Blood Pressure; Body

2001
Brain surface pO2 and rCBF in rabbits with a focal cerebral lesion and pulmonary hypoxia under fentanyl-, isoflurane- or thiopental-anesthesia.
    Advances in experimental medicine and biology, 1992, Volume: 317

    Topics: Anesthesia, General; Animals; Brain; Brain Injuries; Cerebral Cortex; Fentanyl; Hypoxia; Isoflurane;

1992
The influence of a cryogenic brain injury on the cerebrovascular response to isoflurane in the rabbit.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1991, Volume: 11, Issue:3

    Topics: Angiotensin II; Animals; Blood Flow Velocity; Blood Pressure; Brain Injuries; Cerebrovascular Circul

1991
The effect of pentobarbital and isoflurane on glucose metabolism in thermally injured rat brain.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1990, Volume: 10, Issue:5

    Topics: Animals; Autoradiography; Brain Injuries; Disease Models, Animal; Freezing; Glucose; Isoflurane; Mal

1990
A comparison of the effects of halothane, isoflurane, and pentobarbital anesthesia on intracranial pressure and cerebral edema formation following brain injury in rabbits.
    Anesthesiology, 1989, Volume: 71, Issue:4

    Topics: Anesthesia; Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Brain Edema; Brain Injuries; C

1989
The intracranial pressure effects of isoflurane and halothane administered following cryogenic brain injury in rabbits.
    Anesthesiology, 1987, Volume: 67, Issue:4

    Topics: Animals; Brain Injuries; Carbon Dioxide; Cold Temperature; Halothane; Intracranial Pressure; Isoflur

1987
[Effect of isoflurane on intracranial pressure].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1987, Volume: 22, Issue:5

    Topics: Anesthesia, General; Anesthesia, Inhalation; Brain Injuries; Brain Neoplasms; Dose-Response Relation

1987