isoflurane has been researched along with Brain Diseases in 10 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pathophysiological degeneration in hippocampus is one of the primary hallmarks of PND pathology, and long-term isoflurane anesthesia contributes to oxidative stress and neuroinflammation in the hippocampus." | 8.12 | Enhancement of astrocytic gap junctions Connexin43 coupling can improve long-term isoflurane anesthesia-mediated brain network abnormalities and cognitive impairment. ( Dong, R; Gu, X; Han, Y; Jiang, L; Lv, P; Ma, Z; Peng, L; Wang, Z; Xia, T; Zhang, B, 2022) |
| "5% isoflurane posttreatment, there was a significant reduction in brain edema, a decrease in apoptotic cell death, and a significant improvement in neurobehavioral deficits." | 7.77 | Isoflurane posttreatment reduces brain injury after an intracerebral hemorrhagic stroke in mice. ( Applegate, R; Fathali, N; Khatibi, NH; Ma, Q; Martin, R; Ostrowski, R; Rolland, W; Stier, G; Tang, J; Zhang, JH, 2011) |
| " Pathophysiological degeneration in hippocampus is one of the primary hallmarks of PND pathology, and long-term isoflurane anesthesia contributes to oxidative stress and neuroinflammation in the hippocampus." | 4.12 | Enhancement of astrocytic gap junctions Connexin43 coupling can improve long-term isoflurane anesthesia-mediated brain network abnormalities and cognitive impairment. ( Dong, R; Gu, X; Han, Y; Jiang, L; Lv, P; Ma, Z; Peng, L; Wang, Z; Xia, T; Zhang, B, 2022) |
| "5% isoflurane posttreatment, there was a significant reduction in brain edema, a decrease in apoptotic cell death, and a significant improvement in neurobehavioral deficits." | 3.77 | Isoflurane posttreatment reduces brain injury after an intracerebral hemorrhagic stroke in mice. ( Applegate, R; Fathali, N; Khatibi, NH; Ma, Q; Martin, R; Ostrowski, R; Rolland, W; Stier, G; Tang, J; Zhang, JH, 2011) |
| "Isoflurane is an effective neuroprotective drug in a canine cardiac arrest model in terms of both functional and biochemical criteria." | 1.31 | Isoflurane pretreatment ameliorates postischemic neurologic dysfunction and preserves hippocampal Ca2+/calmodulin-dependent protein kinase in a canine cardiac arrest model. ( Adamo, A; Beckman, J; Blanck, TJ; Haile, M; Heerdt, P; Hemmings, H; Kang, R; Veselis, RA; Xu, F; Zhang, J, 2000) |
| "In flurothyl-treated rats, there were significant reductions in SNPR neuropathologic grade (P = 0." | 1.29 | Effect of anesthetics on neuropathologic sequelae of status epilepticus in rats. ( Garman, RH; Graybeal, JM; Hawkins, RA; Housman, C; Kofke, WA; Towfighi, J, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, R | 1 |
| Lv, P | 1 |
| Han, Y | 1 |
| Jiang, L | 1 |
| Wang, Z | 1 |
| Peng, L | 1 |
| Ma, Z | 1 |
| Xia, T | 1 |
| Zhang, B | 1 |
| Gu, X | 1 |
| Khatibi, NH | 1 |
| Ma, Q | 1 |
| Rolland, W | 1 |
| Ostrowski, R | 1 |
| Fathali, N | 1 |
| Martin, R | 1 |
| Applegate, R | 1 |
| Stier, G | 1 |
| Tang, J | 1 |
| Zhang, JH | 1 |
| Kofke, WA | 1 |
| Towfighi, J | 1 |
| Garman, RH | 1 |
| Graybeal, JM | 1 |
| Housman, C | 1 |
| Hawkins, RA | 1 |
| Blanck, TJ | 1 |
| Haile, M | 1 |
| Xu, F | 1 |
| Zhang, J | 1 |
| Heerdt, P | 1 |
| Veselis, RA | 1 |
| Beckman, J | 1 |
| Kang, R | 1 |
| Adamo, A | 1 |
| Hemmings, H | 1 |
| Agardh, CD | 1 |
| Smith, ML | 1 |
| Siesjö, BK | 1 |
| Beemer, GH | 1 |
| Dawson, PJ | 1 |
| Bjorksten, AR | 1 |
| Edwards, NE | 1 |
| Righini, ER | 1 |
| Abballe, C | 1 |
| Sabato, AF | 1 |
| Stefanelli, A | 1 |
| Calimici, R | 1 |
| Morelli Sbarra, G | 1 |
| Neidhardt, A | 1 |
| Bettinger, G | 1 |
| Lazar, JP | 1 |
| Balvay, P | 1 |
| Costes, Y | 1 |
| Michenfelder, JD | 1 |
1 review available for isoflurane and Brain Diseases
| Article | Year |
|---|---|
Cerebral preservation for intraoperative focal ischemia.
Topics: Adenosine Triphosphate; Anesthesia; Anesthetics; Aneurysm; Animals; Barbiturates; Brain; Brain Disea | 1985 |
9 other studies available for isoflurane and Brain Diseases
| Article | Year |
|---|---|
Enhancement of astrocytic gap junctions Connexin43 coupling can improve long-term isoflurane anesthesia-mediated brain network abnormalities and cognitive impairment.
Topics: Anesthesia; Animals; Astrocytes; Brain; Brain Diseases; Cognitive Dysfunction; Connexin 43; Gap Junc | 2022 |
Isoflurane posttreatment reduces brain injury after an intracerebral hemorrhagic stroke in mice.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Basal Ganglia; Behavior, Animal; Body Water; Brain; Bra | 2011 |
Effect of anesthetics on neuropathologic sequelae of status epilepticus in rats.
Topics: 3-Mercaptopropionic Acid; Administration, Inhalation; Anesthetics; Animals; Brain Diseases; Flurothy | 1993 |
Isoflurane pretreatment ameliorates postischemic neurologic dysfunction and preserves hippocampal Ca2+/calmodulin-dependent protein kinase in a canine cardiac arrest model.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Blotting, Western; Brain Diseases; Calcium; Calciu | 2000 |
The influence of hypothermia on hypoglycemia-induced brain damage in the rat.
Topics: Animals; Blood Glucose; Body Temperature; Brain; Brain Diseases; Halothane; Hypoglycemia; Hypothermi | 1992 |
Early postoperative seizures in neurosurgical patients administered atracurium and isoflurane.
Topics: Adolescent; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, General; Atracurium; Br | 1989 |
[Use of isoflurane in the neurologic diagnosis of pediatric patients].
Topics: Anesthesia, General; Brain Diseases; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Isofl | 1987 |
[Hypoxia and protection of the brain (isoflurane vs halothane and enflurane].
Topics: Anesthesia, Inhalation; Animals; Brain Diseases; Enflurane; Female; Halothane; Hypoxia; Isoflurane; | 1987 |
[Closed-circuit isoflurane and controlled ventilation in neurosurgery].
Topics: Anesthesia, Closed-Circuit; Anesthesia, Inhalation; Brain Diseases; Humans; Intervertebral Disc Disp | 1987 |