Page last updated: 2024-10-29

isoflurane and Asystole

isoflurane has been researched along with Asystole in 24 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Research Excerpts

ExcerptRelevanceReference
" In the current study, we investigated whether isoflurane inhalation during warm ischemia could attenuate ischemia reperfusion injury (IRI) of the lung."7.73Isoflurane inhalation after circulatory arrest protects against warm ischemia reperfusion injury of the lungs. ( Bando, T; Chen, F; Fujinaga, T; Fukuse, T; Hamakawa, H; Hanaoka, N; Nakamura, T; Omasa, M; Sakai, H; Ueda, S; Wada, H; Zhang, J, 2006)
"An 8-year-old boy known to have Duchenne's muscular dystrophy suffered a cardiac arrest 10 minutes after he regained consciousness after isoflurane anaesthesia for an orchidopexy procedure."7.68Cardiac arrest after isoflurane anaesthesia in a patient with Duchenne's muscular dystrophy. ( Branch, KG; Chalkiadis, GA, 1990)
" In the current study, we investigated whether isoflurane inhalation during warm ischemia could attenuate ischemia reperfusion injury (IRI) of the lung."3.73Isoflurane inhalation after circulatory arrest protects against warm ischemia reperfusion injury of the lungs. ( Bando, T; Chen, F; Fujinaga, T; Fukuse, T; Hamakawa, H; Hanaoka, N; Nakamura, T; Omasa, M; Sakai, H; Ueda, S; Wada, H; Zhang, J, 2006)
" The patient had had paroxysmal atrial fibrillation for one year and had been treated with digoxin and cibenzoline succinate."3.70[Sudden cardiac arrest after induction of general anesthesia: a case report]. ( Kabutan, K; Mishima, M; Morimoto, N; Takehisa, S; Taniguchi, M, 2000)
"An 8-year-old boy known to have Duchenne's muscular dystrophy suffered a cardiac arrest 10 minutes after he regained consciousness after isoflurane anaesthesia for an orchidopexy procedure."3.68Cardiac arrest after isoflurane anaesthesia in a patient with Duchenne's muscular dystrophy. ( Branch, KG; Chalkiadis, GA, 1990)
"Targeted temperature management after cardiac arrest requires deep sedation to prevent shivering and discomfort."1.46Isoflurane Sedation on the ICU in Cardiac Arrest Patients Treated With Targeted Temperature Management: An Observational Propensity-Matched Study. ( Engels, M; Jörres, A; Krannich, A; Kruse, J; Leithner, C; Nee, J; Petzinka, V; Schröder, T; Storm, C, 2017)
"Post-cardiac arrest myocardial dysfunction and brain injury are the main clinical features of this complex pathophysiological process."1.42Cardiocerebral protection by emulsified isoflurane during cardiopulmonary resuscitation. ( Li, Y; Wu, MJ; Yu, H; Zhang, YJ, 2015)
"Isoflurane sedation was changed to midazolam in two nonsurviving patients because of hemodynamic instability, which persisted despite the change."1.40Inhaled isoflurane sedation during therapeutic hypothermia after cardiac arrest: a case series. ( Hellström, J; Martling, CR; Öwall, A; Sackey, PV, 2014)
"Mouse models of global cerebral ischemia are essential tools to study the molecular mechanisms involved in ischemic brain damage."1.39Guidelines for using mouse global cerebral ischemia models. ( Hu, B; Kristian, T, 2013)
"10 min after CPR from 8 min of cardiac arrest 21 pigs were randomized to three groups (n=7/group) and then ventilated for 1h with gas mixtures as follows: (1) control: 30% O(2)+70% N(2); (2) Iso: 30% O(2)+69% N(2)+1% Iso; (3) Xe: 30% O(2)+70% Xe."1.35Early administration of xenon or isoflurane may not improve functional outcome and cerebral alterations in a porcine model of cardiac arrest. ( Coburn, M; Fries, M; Kottmann, K; Kuru, TH; Nolte, KW; Rossaint, R; Timper, A; Weis, J, 2009)
"Asphyxial cardiopulmonary arrest was induced and, after and 8 min cardiac arrest nonintervention interval, a standardized protocol of manual CPR with mechanical ventilation was performed."1.30Anesthetic regimen effects on a pediatric porcine model of asphyxial arrest. ( Ginn, A; Jasani, MS; Nadkarni, VM; Salzman, SK; Tice, LL, 1997)
"Bupivacaine was infused at a constant rate while the pigs' ECGs and EEGs were recorded."1.28Bupivacaine toxicity in young pigs is age-dependent and is affected by volatile anesthetics. ( Badgwell, JM; Heavner, JE; Kytta, J, 1990)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's5 (20.83)18.2507
2000's7 (29.17)29.6817
2010's11 (45.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Staudacher, DL1
Hamilton, SK1
Duerschmied, D1
Biever, PM1
Zehender, M1
Bode, C1
Wengenmayer, T1
Hellström, J1
Öwall, A1
Martling, CR1
Sackey, PV1
Kristian, T1
Hu, B1
Berger, M1
Warner, DS1
McDonagh, DL1
Zhang, YJ1
Wu, MJ1
Li, Y1
Yu, H1
Orr, TM1
Orr, DL1
Seehase, M2
Houthuizen, P2
Collins, JJ2
Zimmermann, LJ1
Kramer, BW2
Krannich, A1
Leithner, C1
Engels, M1
Nee, J1
Petzinka, V1
Schröder, T1
Jörres, A1
Kruse, J1
Storm, C1
Fries, M2
Coburn, M1
Nolte, KW1
Timper, A2
Kottmann, K2
Kuru, TH1
Weis, J1
Rossaint, R2
Poole, TC1
Lim, TY1
Buck, J1
Kong, AS1
Derwall, M1
Yamamoto, T1
Honma, T1
Ikoma, M1
Baba, H1
Kohno, T1
Jellema, RK1
Bekers, O1
Breuer, J1
Smelt, WL1
Girshin, M1
Mukherjee, J1
Clowney, R1
Singer, LP1
Wasnick, J1
Fujinaga, T1
Nakamura, T1
Fukuse, T1
Chen, F1
Zhang, J1
Ueda, S1
Hamakawa, H1
Omasa, M1
Sakai, H1
Hanaoka, N1
Wada, H1
Bando, T1
Hantler, CB1
Larson, LO1
Shea, MJ1
Zelenock, GB1
Bolling, SF1
Gajek, H1
Jasani, MS1
Salzman, SK1
Tice, LL1
Ginn, A1
Nadkarni, VM1
Kabutan, K1
Mishima, M1
Takehisa, S1
Morimoto, N1
Taniguchi, M1
Kurth, CD1
Priestley, M1
Watzman, HM1
McCann, J1
Golden, J1
Larach, DR1
Chalkiadis, GA1
Branch, KG1
Badgwell, JM1
Heavner, JE1
Kytta, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05327296]Phase 3235 participants (Anticipated)Interventional2022-06-30Recruiting
A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05312385]Phase 3235 participants (Anticipated)Interventional2022-04-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

24 other studies available for isoflurane and Asystole

ArticleYear
Isoflurane or propofol sedation in patients with targeted temperature management after cardiopulmonary resuscitation: A single center study.
    Journal of critical care, 2018, Volume: 45

    Topics: Aged; Cardiopulmonary Resuscitation; Coma; Female; Heart Arrest; Humans; Hypnotics and Sedatives; Hy

2018
Inhaled isoflurane sedation during therapeutic hypothermia after cardiac arrest: a case series.
    Critical care medicine, 2014, Volume: 42, Issue:2

    Topics: Administration, Inhalation; Aged; Deep Sedation; Female; Heart Arrest; Humans; Hypothermia, Induced;

2014
Guidelines for using mouse global cerebral ischemia models.
    Translational stroke research, 2013, Volume: 4, Issue:3

    Topics: Animals; Blood Pressure; Brain; Brain Damage, Chronic; Brain Ischemia; Disease Models, Animal; Heart

2013
Volatile anesthetic sedation during therapeutic hypothermia after cardiac arrest in the ICU: a journey of a thousand miles begins with a single step.
    Critical care medicine, 2014, Volume: 42, Issue:2

    Topics: Deep Sedation; Female; Heart Arrest; Humans; Hypothermia, Induced; Isoflurane; Male

2014
Cardiocerebral protection by emulsified isoflurane during cardiopulmonary resuscitation.
    Medical hypotheses, 2015, Volume: 84, Issue:1

    Topics: Cardiopulmonary Resuscitation; Heart Arrest; Humans; Hypothermia, Induced; Ischemic Postconditioning

2015
Pulseless Ventricular Tachycardia During Office-Based Anesthetic in a Four-Year-Old Child.
    Anesthesia progress, 2015,Winter, Volume: 62, Issue:4

    Topics: Advanced Cardiac Life Support; Anesthesia, Dental; Anesthesia, Inhalation; Anesthetics, Inhalation;

2015
Propofol administration to the fetal-maternal unit reduces cardiac oxidative stress in preterm lambs subjected to prenatal asphyxia and cardiac arrest.
    Pediatric research, 2016, Volume: 79, Issue:5

    Topics: Animals; Animals, Newborn; Asphyxia; Asphyxia Neonatorum; Cardiac Myosins; Echocardiography; Female;

2016
Isoflurane Sedation on the ICU in Cardiac Arrest Patients Treated With Targeted Temperature Management: An Observational Propensity-Matched Study.
    Critical care medicine, 2017, Volume: 45, Issue:4

    Topics: Administration, Inhalation; Administration, Intravenous; Aged; Anesthetics, Inhalation; Anesthetics,

2017
Isoflurane Sedation on the ICU in Cardiac Arrest Patients Treated With Targeted Temperature Management: An Observational Propensity-Matched Study.
    Critical care medicine, 2017, Volume: 45, Issue:4

    Topics: Administration, Inhalation; Administration, Intravenous; Aged; Anesthetics, Inhalation; Anesthetics,

2017
Isoflurane Sedation on the ICU in Cardiac Arrest Patients Treated With Targeted Temperature Management: An Observational Propensity-Matched Study.
    Critical care medicine, 2017, Volume: 45, Issue:4

    Topics: Administration, Inhalation; Administration, Intravenous; Aged; Anesthetics, Inhalation; Anesthetics,

2017
Isoflurane Sedation on the ICU in Cardiac Arrest Patients Treated With Targeted Temperature Management: An Observational Propensity-Matched Study.
    Critical care medicine, 2017, Volume: 45, Issue:4

    Topics: Administration, Inhalation; Administration, Intravenous; Aged; Anesthetics, Inhalation; Anesthetics,

2017
Early administration of xenon or isoflurane may not improve functional outcome and cerebral alterations in a porcine model of cardiac arrest.
    Resuscitation, 2009, Volume: 80, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Brain; Cardiopulmonary Resuscitation; Disease Models, Animal; Drug

2009
Perioperative cardiac arrest in a patient with previously undiagnosed Becker's muscular dystrophy after isoflurane anaesthesia for elective surgery.
    British journal of anaesthesia, 2010, Volume: 104, Issue:4

    Topics: Acute Disease; Anesthetics, Inhalation; Child; Circumcision, Male; Heart Arrest; Humans; Hyperkalemi

2010
Neuroprotective effects of the inhalational anesthetics isoflurane and xenon after cardiac arrest in pigs.
    Critical care medicine, 2008, Volume: 36, Issue:11 Suppl

    Topics: Anesthetics, Inhalation; Animals; Cardiac Output; Cardiopulmonary Resuscitation; Cognition Disorders

2008
[Case of profound bradycardia and cardiac arrest during left upper lobectomy and lymph node dissection].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59, Issue:12

    Topics: Anesthesia, Epidural; Anesthesia, General; Bradycardia; Cardiac Pacing, Artificial; Electrocoagulati

2010
Propofol administration to the fetal-maternal unit reduces cardiac injury in late-preterm lambs subjected to severe prenatal asphyxia and cardiac arrest.
    Pediatric research, 2013, Volume: 73, Issue:4 Pt 1

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Animals, Newborn; Asphyxia Neonatorum; B

2013
Cardiac arrest during desflurane anaesthesia in a patient with Duchenne's muscular dystrophy.
    Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:2

    Topics: Adolescent; Anesthetics, Inhalation; Blood Loss, Surgical; Bronchodilator Agents; Cardiomyopathies;

2005
The postoperative cardiovascular arrest of a 5-year-old male: an initial presentation of Duchenne's muscular dystrophy.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:2

    Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Gas Analysis; Cardiopulmonary R

2006
Isoflurane inhalation after circulatory arrest protects against warm ischemia reperfusion injury of the lungs.
    Transplantation, 2006, Nov-15, Volume: 82, Issue:9

    Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Blood Circulation; Caspase 9; Cell Res

2006
Case conference. A 55-year-old man develops ventricular tachycardia and cardiac arrest during non-cardiac vascular surgery.
    Journal of cardiothoracic anesthesia, 1987, Volume: 1, Issue:4

    Topics: Anesthesia, General; Anesthetics, Inhalation; Celiac Artery; Chest Pain; Coronary Artery Disease; Di

1987
Cardiac arrest following Haemaccel--comment.
    Anaesthesia and intensive care, 1994, Volume: 22, Issue:6

    Topics: Aged; Aged, 80 and over; Anaphylaxis; Anesthesia, Inhalation; Female; Heart Arrest; Histamine H1 Ant

1994
Anesthetic regimen effects on a pediatric porcine model of asphyxial arrest.
    Resuscitation, 1997, Volume: 35, Issue:1

    Topics: Adjuvants, Anesthesia; Anesthesia, General; Anesthetics, Combined; Anesthetics, Dissociative; Anesth

1997
[Sudden cardiac arrest after induction of general anesthesia: a case report].
    Masui. The Japanese journal of anesthesiology, 2000, Volume: 49, Issue:1

    Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anti-Arrhythmia Agents; Atrial Fibrillation; Bre

2000
Desflurane confers neurologic protection for deep hypothermic circulatory arrest in newborn pigs.
    Anesthesiology, 2001, Volume: 95, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Behavior, Animal; Brain; Cardiopulmonary Bypass;

2001
Direct actions of volatile anesthetics on the coronary vasculature.
    Advances in experimental medicine and biology, 1991, Volume: 301

    Topics: Anesthetics; Animals; Coronary Circulation; Coronary Vessels; Halothane; Heart Arrest; In Vitro Tech

1991
Cardiac arrest after isoflurane anaesthesia in a patient with Duchenne's muscular dystrophy.
    Anaesthesia, 1990, Volume: 45, Issue:1

    Topics: Anesthesia, Inhalation; Child; Heart Arrest; Humans; Isoflurane; Male; Muscular Dystrophies; Postope

1990
Bupivacaine toxicity in young pigs is age-dependent and is affected by volatile anesthetics.
    Anesthesiology, 1990, Volume: 73, Issue:2

    Topics: Aging; Animals; Arrhythmias, Cardiac; Blood Pressure; Bupivacaine; Cardiac Output; Drug Interactions

1990