isoflurane has been researched along with Apoplexy in 21 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examined the comparative effects of sevoflurane versus isoflurane on cerebrovascular CO2 reactivity in patients with previous stroke." | 9.13 | The comparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with previous stroke. ( Kadoi, Y; Saito, S; Takahashi, K, 2008) |
| "We were able to determine the effects of the duration of anesthesia using isoflurane on the transcriptomes in the brains of rats at 24 h after tMCAO." | 8.31 | Isoflurane Anesthesia's Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model. ( Denisova, AE; Dergunova, LV; Filippenkov, IB; Gubsky, LV; Limborska, SA; Shpetko, YY; Stavchansky, VV, 2023) |
| "Cerebral blood flow (CBF) and blood-brain barrier (BBB) permeability by arterial spin labeling (ASL)- and dynamic contrast enhanced (DCE)-magnetic resonance imaging (MRI), respectively were repeatedly measured under either halothane (N = 5) or isoflurane (N = 5) anesthesia in a rat stroke model of embolic occlusion of middle cerebral artery (MCA)." | 7.80 | Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke. ( Alarcon, W; Bezerra, FJ; Brown, M; Karki, K; Keenan, KA; Knight, RA; Nagaraja, TN, 2014) |
| "Since an ethical issue has been raised regarding the use of the well-known anesthetic agent chloral hydrate, owing to its mutagenic and carcinogenic effects in animals, attention of neuroscientists has turned to finding out an alternative agent able to meet not only potency, safety, and analgesic efficacy, but also reduced neuroprotective effect for stroke research." | 7.80 | Evidence for the use of isoflurane as a replacement for chloral hydrate anesthesia in experimental stroke: an ethical issue. ( Cédrick, L; Maud, P; Michèle, B; Olivier, P; Régis, B; Thavarak, O; Vincent, B, 2014) |
| "5% isoflurane posttreatment, there was a significant reduction in brain edema, a decrease in apoptotic cell death, and a significant improvement in neurobehavioral deficits." | 7.77 | Isoflurane posttreatment reduces brain injury after an intracerebral hemorrhagic stroke in mice. ( Applegate, R; Fathali, N; Khatibi, NH; Ma, Q; Martin, R; Ostrowski, R; Rolland, W; Stier, G; Tang, J; Zhang, JH, 2011) |
| "Preclinical evidence in rodents has suggested that inert gases, such as xenon or nitrous oxide, may be promising neuroprotective agents for treating acute ischemic stroke." | 7.77 | Interactions between nitrous oxide and tissue plasminogen activator in a rat model of thromboembolic stroke. ( Abraini, JH; Colloc'h, N; Colomb, DG; David, HN; Haelewyn, B; Risso, JJ, 2011) |
| "Isoflurane post-treatment may enhance autophagy by activating the AMPK/ULK1 signaling pathway and further inhibit the release of inflammatory factors from NLRP3 inflammasomes, thereby ameliorating neurological function and cognitive impairment and exerting a protective effect on the brain in CIRI rats." | 5.91 | Isoflurane Enhances Autophagy by Activating AMPK/ULK1, Inhibits NLRP3, and Reduces Cognitive Impairment After Cerebral Ischemia-Reperfusion Injury in Rats. ( Li, N; Li, Y; Ma, K; Qin, X; Wang, R; Wang, S; Yin, J; Zhai, J; Zhang, X, 2023) |
| "Ischaemic stroke is a severe disease worldwide." | 5.72 | Isoflurane Attenuates Cerebral Ischaemia-Reperfusion Injury via the TLR4-NLRP3 Signalling Pathway in Diabetic Mice. ( Guo, WJ; Hong, P; Huang, XX; Li, FX; Lin, HB; Tang, ZY; Wang, JW; Xu, SY; Zhang, HF; Zhang, YJ, 2022) |
| "Included in the study were 19 consecutive ventilated patients with intracerebral hemorrhage (12), subarachnoid hemorrhage (4), and ischemic stroke (3) who were switched from intravenous propofol or midazolam to inhalative isoflurane sedation for an average of 3." | 5.16 | Volatile isoflurane sedation in cerebrovascular intensive care patients using AnaConDa(®): effects on cerebral oxygenation, circulation, and pressure. ( Bösel, J; Brunn, B; Hacke, W; Nowak, F; Pérez, EB; Poli, S; Purrucker, JC; Renzland, J; Schiller, P; Steiner, T, 2012) |
| " We examined the comparative effects of sevoflurane versus isoflurane on cerebrovascular CO2 reactivity in patients with previous stroke." | 5.13 | The comparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with previous stroke. ( Kadoi, Y; Saito, S; Takahashi, K, 2008) |
| "We were able to determine the effects of the duration of anesthesia using isoflurane on the transcriptomes in the brains of rats at 24 h after tMCAO." | 4.31 | Isoflurane Anesthesia's Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model. ( Denisova, AE; Dergunova, LV; Filippenkov, IB; Gubsky, LV; Limborska, SA; Shpetko, YY; Stavchansky, VV, 2023) |
| " In the present study, we utilized our recently developed photothrombotic model of focal cerebral ischemia in conscious and freely moving rats, and investigated transient hemodynamic changes with or without isoflurane administration." | 3.85 | Hemodynamic effects of intraoperative anesthetics administration in photothrombotic stroke model: a study using laser speckle imaging. ( Bo, B; Li, H; Li, Y; Lu, H; Lu, X; Tong, S; Yuan, L, 2017) |
| "Cerebral blood flow (CBF) and blood-brain barrier (BBB) permeability by arterial spin labeling (ASL)- and dynamic contrast enhanced (DCE)-magnetic resonance imaging (MRI), respectively were repeatedly measured under either halothane (N = 5) or isoflurane (N = 5) anesthesia in a rat stroke model of embolic occlusion of middle cerebral artery (MCA)." | 3.80 | Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke. ( Alarcon, W; Bezerra, FJ; Brown, M; Karki, K; Keenan, KA; Knight, RA; Nagaraja, TN, 2014) |
| "Since an ethical issue has been raised regarding the use of the well-known anesthetic agent chloral hydrate, owing to its mutagenic and carcinogenic effects in animals, attention of neuroscientists has turned to finding out an alternative agent able to meet not only potency, safety, and analgesic efficacy, but also reduced neuroprotective effect for stroke research." | 3.80 | Evidence for the use of isoflurane as a replacement for chloral hydrate anesthesia in experimental stroke: an ethical issue. ( Cédrick, L; Maud, P; Michèle, B; Olivier, P; Régis, B; Thavarak, O; Vincent, B, 2014) |
| "5% isoflurane posttreatment, there was a significant reduction in brain edema, a decrease in apoptotic cell death, and a significant improvement in neurobehavioral deficits." | 3.77 | Isoflurane posttreatment reduces brain injury after an intracerebral hemorrhagic stroke in mice. ( Applegate, R; Fathali, N; Khatibi, NH; Ma, Q; Martin, R; Ostrowski, R; Rolland, W; Stier, G; Tang, J; Zhang, JH, 2011) |
| "Preclinical evidence in rodents has suggested that inert gases, such as xenon or nitrous oxide, may be promising neuroprotective agents for treating acute ischemic stroke." | 3.77 | Interactions between nitrous oxide and tissue plasminogen activator in a rat model of thromboembolic stroke. ( Abraini, JH; Colloc'h, N; Colomb, DG; David, HN; Haelewyn, B; Risso, JJ, 2011) |
| " The authors compared CBF imaging using flow sensitive alternating inversion recovery (FAIR)-MRI and (14)C-Iodoantipyrine (IAP)-autoradiography in a mouse model of acute stroke." | 3.74 | A flow sensitive alternating inversion recovery (FAIR)-MRI protocol to measure hemispheric cerebral blood flow in a mouse stroke model. ( Dirnagl, U; Endres, M; Gertz, K; Leithner, C; Lindauer, U; Prass, K; Priller, J; Royl, G; Schröck, H; Steinbrink, J; Villringer, A, 2008) |
| " Furthermore, most preclinical antiepileptogenic studies lack information needed for translation, such as dose-blood level relationship, brain target engagement, and dose-response, and many use treatment parameters that cannot be applied clinically, for example, treatment initiation before or at the time of injury and dosing higher than tolerated human equivalent dosing." | 2.66 | Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy? ( Bar-Klein, G; Friedman, A; Hameed, MQ; Jozwiak, S; Kaminski, RM; Klein, P; Klitgaard, H; Koepp, M; Löscher, W; Prince, DA; Rotenberg, A; Twyman, R; Vezzani, A; Wong, M, 2020) |
| "Isoflurane post-treatment may enhance autophagy by activating the AMPK/ULK1 signaling pathway and further inhibit the release of inflammatory factors from NLRP3 inflammasomes, thereby ameliorating neurological function and cognitive impairment and exerting a protective effect on the brain in CIRI rats." | 1.91 | Isoflurane Enhances Autophagy by Activating AMPK/ULK1, Inhibits NLRP3, and Reduces Cognitive Impairment After Cerebral Ischemia-Reperfusion Injury in Rats. ( Li, N; Li, Y; Ma, K; Qin, X; Wang, R; Wang, S; Yin, J; Zhai, J; Zhang, X, 2023) |
| "Ischaemic stroke is a severe disease worldwide." | 1.72 | Isoflurane Attenuates Cerebral Ischaemia-Reperfusion Injury via the TLR4-NLRP3 Signalling Pathway in Diabetic Mice. ( Guo, WJ; Hong, P; Huang, XX; Li, FX; Lin, HB; Tang, ZY; Wang, JW; Xu, SY; Zhang, HF; Zhang, YJ, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 9 (42.86) | 24.3611 |
| 2020's | 6 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, YJ | 1 |
| Guo, WJ | 1 |
| Tang, ZY | 1 |
| Lin, HB | 1 |
| Hong, P | 1 |
| Wang, JW | 1 |
| Huang, XX | 1 |
| Li, FX | 1 |
| Xu, SY | 1 |
| Zhang, HF | 1 |
| Mousavi, SM | 1 |
| Karimi-Haghighi, S | 1 |
| Chavoshinezhad, S | 1 |
| Pandamooz, S | 1 |
| Belém-Filho, IJA | 1 |
| Keshavarz, S | 1 |
| Bayat, M | 1 |
| Hooshmandi, E | 1 |
| Rahimi Jaberi, A | 1 |
| Salehi, MS | 1 |
| Borhani-Haghighi, A | 1 |
| Zhai, J | 1 |
| Li, N | 2 |
| Zhang, X | 7 |
| Li, Y | 6 |
| Ma, K | 1 |
| Wang, R | 2 |
| Qin, X | 1 |
| Yin, J | 2 |
| Wang, S | 1 |
| Shpetko, YY | 1 |
| Filippenkov, IB | 1 |
| Denisova, AE | 1 |
| Stavchansky, VV | 1 |
| Gubsky, LV | 1 |
| Limborska, SA | 1 |
| Dergunova, LV | 1 |
| Chen, G | 1 |
| Kamat, PK | 1 |
| Ahmad, AS | 1 |
| Doré, S | 1 |
| Klein, P | 1 |
| Friedman, A | 1 |
| Hameed, MQ | 1 |
| Kaminski, RM | 1 |
| Bar-Klein, G | 1 |
| Klitgaard, H | 1 |
| Koepp, M | 1 |
| Jozwiak, S | 1 |
| Prince, DA | 1 |
| Rotenberg, A | 1 |
| Twyman, R | 1 |
| Vezzani, A | 1 |
| Wong, M | 1 |
| Löscher, W | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 6 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 4 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 2 |
| Xu, G | 1 |
| Xu, N | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 3 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 5 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 3 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 2 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 6 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 2 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 7 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
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| de Swart, J | 1 |
| Verhagen, HJ | 1 |
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| de Jong, M | 1 |
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| Pérez-Camargo, D | 1 |
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| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
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| Cussó, L | 1 |
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| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
| Zhu, X | 1 |
| Huang, X | 2 |
| Xu, H | 2 |
| Yang, G | 2 |
| Lin, Z | 1 |
| Salem, HF | 1 |
| Nafady, MM | 1 |
| Kharshoum, RM | 1 |
| Abd El-Ghafar, OA | 1 |
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| de Carvalho, PA | 1 |
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| Chalfun-Júnior, A | 1 |
| Paiva, R | 1 |
| Marchiori, PER | 1 |
| Lu, M | 2 |
| An, Z | 1 |
| Jiang, J | 2 |
| Li, J | 7 |
| Du, S | 1 |
| Zhou, H | 1 |
| Cui, J | 1 |
| Wu, W | 1 |
| Liu, Y | 7 |
| Song, J | 1 |
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| Uddin Ahmad, Z | 1 |
| Gang, DD | 1 |
| Konggidinata, MI | 1 |
| Gallo, AA | 1 |
| Zappi, ME | 1 |
| Yang, TWW | 1 |
| Johari, Y | 1 |
| Burton, PR | 1 |
| Earnest, A | 1 |
| Shaw, K | 1 |
| Hare, JL | 1 |
| Brown, WA | 1 |
| Kim, GA | 1 |
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| Choi, GH | 1 |
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| Gasbarrini, A | 1 |
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| Wang, F | 1 |
| Han, Z | 1 |
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2 reviews available for isoflurane and Apoplexy
| Article | Year |
|---|---|
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Atorvastatin; Brain Injuries, Traumatic; Cef | 2020 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
3 trials available for isoflurane and Apoplexy
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Volatile isoflurane sedation in cerebrovascular intensive care patients using AnaConDa(®): effects on cerebral oxygenation, circulation, and pressure.
Topics: Aged; Aged, 80 and over; Anesthetics, Inhalation; Cerebral Hemorrhage; Cerebrovascular Circulation; | 2012 |
The comparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with previous stroke.
Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Flow Velocity; Carbon Di | 2008 |
17 other studies available for isoflurane and Apoplexy
| Article | Year |
|---|---|
Isoflurane Attenuates Cerebral Ischaemia-Reperfusion Injury via the TLR4-NLRP3 Signalling Pathway in Diabetic Mice.
Topics: Animals; Brain Ischemia; Diabetes Mellitus, Experimental; Humans; Infarction, Middle Cerebral Artery | 2022 |
The impacts of anesthetic regimens on the middle cerebral artery occlusion outcomes in male rats.
Topics: Anesthetics; Animals; Humans; Infarction, Middle Cerebral Artery; Isoflurane; Ketamine; Male; Rats; | 2022 |
Isoflurane Enhances Autophagy by Activating AMPK/ULK1, Inhibits NLRP3, and Reduces Cognitive Impairment After Cerebral Ischemia-Reperfusion Injury in Rats.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Brain Ischem | 2023 |
Isoflurane Anesthesia's Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model.
Topics: Anesthesia; Animals; Brain; Disease Models, Animal; Gene Expression; Gene Expression Regulation; Isc | 2023 |
Distinctive effect of anesthetics on the effect of limb remote ischemic postconditioning following ischemic stroke.
Topics: Analgesics; Anesthetics; Animals; Brain Infarction; Brain Ischemia; Extremities; Halothane; Infarcti | 2020 |
Isoflurane preconditioning inhibits the effects of tissue-type plasminogen activator on brain endothelial cell in an
Topics: Animals; Apoptosis; Brain Injuries; Brain Ischemia; Culture Media, Conditioned; Cyclooxygenase 2; Di | 2017 |
Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke.
Topics: Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Brain Ischemia; Cerebrovascular Circulation; | 2014 |
Evidence for the use of isoflurane as a replacement for chloral hydrate anesthesia in experimental stroke: an ethical issue.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Bioethical Issues; Chloral Hydrate; Disease Models, An | 2014 |
Isoflurane preconditioning provides neuroprotection against stroke by regulating the expression of the TLR4 signalling pathway to alleviate microglial activation.
Topics: Animals; Apoptosis; Biomarkers; Brain Infarction; Cells, Cultured; Chaperonin 60; Disease Models, An | 2015 |
Hemodynamic effects of intraoperative anesthetics administration in photothrombotic stroke model: a study using laser speckle imaging.
Topics: Anesthetics, Inhalation; Animals; Brain; Brain Ischemia; Disease Models, Animal; Hemodynamics; Isofl | 2017 |
Contemporary conduct of adult deep hypothermic circulatory arrest: possible roles of retrograde cerebral perfusion, anesthetic preconditioning, and aprotinin.
Topics: Adult; Anesthetics, Inhalation; Aorta, Thoracic; Aprotinin; Brain; Cerebrovascular Circulation; Hear | 2008 |
Isoflurane posttreatment reduces brain injury after an intracerebral hemorrhagic stroke in mice.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Basal Ganglia; Behavior, Animal; Body Water; Brain; Bra | 2011 |
Interactions between nitrous oxide and tissue plasminogen activator in a rat model of thromboembolic stroke.
Topics: Animals; Binding Sites; Brain; Disease Models, Animal; Isoflurane; Male; N-Methylaspartate; Neuropro | 2011 |
Postischemic nitrous oxide alone versus intraischemic nitrous oxide in the presence of isoflurane: what it may change for neuroprotection against cerebral stroke in the rat.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Brain Ischemia; Drug Interactions; Isoflurane; N | 2005 |
Intraoperative stroke during carotid endarterectomy without a change in the spectral edge frequency of the compressed spectral array.
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Aphasia; Electroencephalography; Endarterec | 1988 |
Perioperative stroke.
Topics: Anesthesia, Conduction; Anesthesia, General; Anesthetics; Humans; Hypotension; Isoflurane; Postopera | 2007 |
A flow sensitive alternating inversion recovery (FAIR)-MRI protocol to measure hemispheric cerebral blood flow in a mouse stroke model.
Topics: Anesthetics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Autoradiography; Blood Ci | 2008 |