isoflurane has been researched along with Anoxia-Ischemia, Brain in 20 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isoflurane is a volatile anesthetic that is widely used clinically as an inhalational anesthetic." | 2.49 | Isoflurane provides neuroprotection in neonatal hypoxic ischemic brain injury. ( Burchell, SR; Dixon, BJ; Tang, J; Zhang, JH, 2013) |
| "Traumatic brain injuries remain an area of great challenge to both neurosurgeons and neuroanaesthesiologists." | 2.45 | Traumatic brain injury: neuroprotective anaesthetic techniques, an update. ( Aal-Shaya, WA; Al-Faridi, K; Halawani, MM; Taha, WS; Tawfeeq, NA, 2009) |
| "Mangiferin is a natural polyphenol with various pharmacological properties, including antioxidant and ant-tumor effects." | 1.48 | Mangiferin Potentiates Neuroprotection by Isoflurane in Neonatal Hypoxic Brain Injury by Reducing Oxidative Stress and Activation of Phosphatidylinositol-3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling. ( Long, XX; Ma, Y; Wang, YF; Xi, JS, 2018) |
| "Isoflurane posttreatment was evaluated for effects on infarct volume at 48 hours after HI and brain atrophy and neurological outcomes at 4 weeks after HI." | 1.36 | Isoflurane posttreatment reduces neonatal hypoxic-ischemic brain injury in rats by the sphingosine-1-phosphate/phosphatidylinositol-3-kinase/Akt pathway. ( Fathali, N; Lekic, T; Martin, RD; Ostrowski, RP; Tang, J; Zhang, JH; Zhou, Y, 2010) |
| "Isoflurane has been shown to induce tolerance against ischaemic injury in adult rodents." | 1.35 | Isoflurane exerts a short-term but not a long-term preconditioning effect in neonatal rats exposed to a hypoxic-ischaemic neuronal injury. ( Furuya, H; Kawaguchi, M; Kawaraguchi, Y; Konishi, N; Nakamura, M; Patel, H; Patel, PM; Sasaoka, N, 2009) |
| "10 min after CPR from 8 min of cardiac arrest 21 pigs were randomized to three groups (n=7/group) and then ventilated for 1h with gas mixtures as follows: (1) control: 30% O(2)+70% N(2); (2) Iso: 30% O(2)+69% N(2)+1% Iso; (3) Xe: 30% O(2)+70% Xe." | 1.35 | Early administration of xenon or isoflurane may not improve functional outcome and cerebral alterations in a porcine model of cardiac arrest. ( Coburn, M; Fries, M; Kottmann, K; Kuru, TH; Nolte, KW; Rossaint, R; Timper, A; Weis, J, 2009) |
| "Isoflurane was applied after OGD." | 1.35 | Postconditioning with isoflurane reduced ischemia-induced brain injury in rats. ( Jung, HH; Lee, JJ; Li, L; Zuo, Z, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (45.00) | 29.6817 |
| 2010's | 11 (55.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barkhuizen, M | 1 |
| van Dijck, FJP | 1 |
| Jellema, RK | 1 |
| Gussenhoven, R | 1 |
| Engelbertink, I | 1 |
| van Mechelen, R | 1 |
| Cleutjens, JPM | 1 |
| Seehase, M | 1 |
| Steinbusch, HWM | 1 |
| Zimmermann, LJ | 1 |
| Gavilanes, AWD | 1 |
| Kramer, BW | 1 |
| Xi, JS | 1 |
| Wang, YF | 1 |
| Long, XX | 1 |
| Ma, Y | 1 |
| Burchell, SR | 1 |
| Dixon, BJ | 1 |
| Tang, J | 2 |
| Zhang, JH | 2 |
| Zhao, P | 3 |
| Ji, G | 2 |
| Xue, H | 2 |
| Yu, W | 2 |
| Zhao, X | 1 |
| Ding, M | 2 |
| Yang, Y | 2 |
| Zuo, Z | 4 |
| Sosunov, SA | 1 |
| Ameer, X | 1 |
| Niatsetskaya, ZV | 1 |
| Utkina-Sosunova, I | 1 |
| Ratner, VI | 1 |
| Ten, VS | 1 |
| Xu, Y | 1 |
| Han, G | 1 |
| Wang, F | 1 |
| Wang, Q | 1 |
| Yin, J | 1 |
| Wang, S | 2 |
| Cui, D | 1 |
| Lin, H | 1 |
| Ge, M | 1 |
| Dai, Z | 1 |
| Xie, L | 1 |
| Si, J | 1 |
| Ma, K | 1 |
| Li, L | 3 |
| Zhao, L | 1 |
| Sasaoka, N | 1 |
| Kawaguchi, M | 1 |
| Kawaraguchi, Y | 1 |
| Nakamura, M | 1 |
| Konishi, N | 1 |
| Patel, H | 1 |
| Patel, PM | 1 |
| Furuya, H | 1 |
| Fries, M | 1 |
| Coburn, M | 1 |
| Nolte, KW | 1 |
| Timper, A | 1 |
| Kottmann, K | 1 |
| Kuru, TH | 1 |
| Weis, J | 1 |
| Rossaint, R | 1 |
| Katz, LM | 1 |
| Frank, JE | 1 |
| Dvorak, A | 1 |
| Finch, A | 1 |
| Szymanowski, A | 1 |
| Gordon, CJ | 1 |
| McAuliffe, JJ | 2 |
| Loepke, AW | 1 |
| Miles, L | 1 |
| Joseph, B | 2 |
| Hughes, E | 1 |
| Vorhees, CV | 2 |
| Tawfeeq, NA | 1 |
| Halawani, MM | 1 |
| Al-Faridi, K | 1 |
| Aal-Shaya, WA | 1 |
| Taha, WS | 1 |
| Bickler, PE | 1 |
| Fahlman, CS | 1 |
| Zhou, Y | 1 |
| Lekic, T | 1 |
| Fathali, N | 1 |
| Ostrowski, RP | 1 |
| Martin, RD | 1 |
| Guo, SX | 1 |
| Dai, ZG | 1 |
| Dong, XW | 1 |
| Liu, Y | 1 |
| Jiang, S | 1 |
| Wang, ZP | 1 |
| Faulkner, SD | 1 |
| Downie, NA | 1 |
| Mercer, CJ | 1 |
| Kerr, SA | 1 |
| Sanders, RD | 1 |
| Robertson, NJ | 1 |
| Wang, Y | 1 |
| Huang, Y | 1 |
| Peng, L | 1 |
| Xu, X | 1 |
| Lee, JJ | 1 |
| Jung, HH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Delirium Reduction by Volatile Anesthesia in Cardiac Surgery: Prospective, Randomized, Single-blinded Study[NCT03729011] | Phase 4 | 672 participants (Anticipated) | Interventional | 2019-01-09 | Recruiting | ||
| Inhalatorial Sedation in Patient With SAH Versus Conventional Intravenous Sedation (GAS-SAH)[NCT00830843] | Phase 4 | 13 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for isoflurane and Anoxia-Ischemia, Brain
| Article | Year |
|---|---|
Isoflurane provides neuroprotection in neonatal hypoxic ischemic brain injury.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Brain; Humans; Hypoxia-Ischemia, Brain; Infant, | 2013 |
Traumatic brain injury: neuroprotective anaesthetic techniques, an update.
Topics: Adolescent; Adult; Brain Injuries; Cell Death; Central Nervous System Depressants; Craniocerebral Tr | 2009 |
18 other studies available for isoflurane and Anoxia-Ischemia, Brain
| Article | Year |
|---|---|
The influence of anesthetics on substantia nigra tyrosine hydroxylase expression and tau phosphorylation in the hypoxic-ischemic near-term lamb.
Topics: Anesthetics; Animals; Animals, Newborn; Brain Mapping; Dopamine; Dopaminergic Neurons; Female; Gluta | 2018 |
Mangiferin Potentiates Neuroprotection by Isoflurane in Neonatal Hypoxic Brain Injury by Reducing Oxidative Stress and Activation of Phosphatidylinositol-3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling.
Topics: Animals; Antioxidants; Hypoxia; Hypoxia-Ischemia, Brain; Hypoxia, Brain; Isoflurane; Neuroprotection | 2018 |
Isoflurane postconditioning improved long-term neurological outcome possibly via inhibiting the mitochondrial permeability transition pore in neonatal rats after brain hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Atractyloside; CA3 Region, Hippocampal; Carotid Artery, Common; Central N | 2014 |
Isoflurane anesthesia initiated at the onset of reperfusion attenuates oxidative and hypoxic-ischemic brain injury.
Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Cerebrovascular Circulation; Disease Models, A | 2015 |
Isoflurane postconditioning induces concentration- and timing-dependent neuroprotection partly mediated by the GluR2 AMPA receptor in neonatal rats after brain hypoxia-ischemia.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Body Weight; Female; Hypoxia-Ischemia, Brain; Is | 2016 |
Effects of activin A and its downstream ERK1/2 in oxygen and glucose deprivation after isoflurane-induced postconditioning.
Topics: Animals; Cell Hypoxia; Cell Survival; Cytoprotection; Dose-Response Relationship, Drug; Glucose; Hip | 2016 |
Isoflurane exerts a short-term but not a long-term preconditioning effect in neonatal rats exposed to a hypoxic-ischaemic neuronal injury.
Topics: Animals; Animals, Newborn; Arteries; Blood Gas Analysis; Hypoxia-Ischemia, Brain; Ischemic Precondit | 2009 |
Early administration of xenon or isoflurane may not improve functional outcome and cerebral alterations in a porcine model of cardiac arrest.
Topics: Anesthetics, Inhalation; Animals; Brain; Cardiopulmonary Resuscitation; Disease Models, Animal; Drug | 2009 |
Independence of brain and trunk temperature during hypothermic preconditioning in rats.
Topics: Anesthetics, Inhalation; Animals; Artifacts; Body Temperature; Brain; Cerebrovascular Circulation; H | 2009 |
Desflurane, isoflurane, and sevoflurane provide limited neuroprotection against neonatal hypoxia-ischemia in a delayed preconditioning paradigm.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Blood Gas Analysi | 2009 |
Enhanced hypoxic preconditioning by isoflurane: signaling gene expression and requirement of intracellular Ca2+ and inositol triphosphate receptors.
Topics: Anesthetics, Inhalation; Animals; Calcium; Calcium Signaling; Cations, Divalent; Gene Expression Reg | 2010 |
Isoflurane posttreatment reduces neonatal hypoxic-ischemic brain injury in rats by the sphingosine-1-phosphate/phosphatidylinositol-3-kinase/Akt pathway.
Topics: Animals; Animals, Newborn; Hypoxia-Ischemia, Brain; Isoflurane; Lysophospholipids; Neuroprotective A | 2010 |
Dual isoflurane-induced preconditioning improves neuroprotection in rat brain in vitro and the role of extracellular signal--regulated protein kinase.
Topics: Anesthetics, Inhalation; Animals; Enzyme Inhibitors; Hippocampus; Hypoxia-Ischemia, Brain; Ischemic | 2011 |
A xenon recirculating ventilator for the newborn piglet: developing clinical applications of xenon for neonates.
Topics: Air; Anesthesiology; Animals; Animals, Newborn; Automation; Calibration; Hypoxia-Ischemia, Brain; Is | 2012 |
Isoflurane preconditioning protects human neuroblastoma SH-SY5Y cells against in vitro simulated ischemia-reperfusion through the activation of extracellular signal-regulated kinases pathway.
Topics: Butadienes; Cell Hypoxia; Cell Line, Tumor; Cell Survival; DNA, Single-Stranded; Dose-Response Relat | 2006 |
Isoflurane-delayed preconditioning reduces immediate mortality and improves striatal function in adult mice after neonatal hypoxia-ischemia.
Topics: Age Factors; Animals; Animals, Newborn; Corpus Striatum; Female; Hypoxia-Ischemia, Brain; Ischemic P | 2007 |
Isoflurane preconditioning improves long-term neurologic outcome after hypoxic-ischemic brain injury in neonatal rats.
Topics: Animals; Animals, Newborn; Female; Hypoxia-Ischemia, Brain; Ischemic Preconditioning; Isoflurane; Ma | 2007 |
Postconditioning with isoflurane reduced ischemia-induced brain injury in rats.
Topics: Anesthetics, Inhalation; Animals; Brain; Decanoic Acids; Dose-Response Relationship, Drug; Glyburide | 2008 |