Page last updated: 2024-10-29

isoflurane and Anoxia, Brain

isoflurane has been researched along with Anoxia, Brain in 11 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Research Excerpts

ExcerptRelevanceReference
"Patients with subarachnoid hemorrhage were prospectively separated into groups with modest (Fisher grade 1 or 2; n = 8) and severe bleeds (Fisher grade 3; n = 7)."2.69Hypoxic brain tissue following subarachnoid hemorrhage. ( Ausman, JI; Charbel, FT; Edelman, G; Hoffman, WE; Torres, NJ; Wheeler, P, 2000)
"Mangiferin is a natural polyphenol with various pharmacological properties, including antioxidant and ant-tumor effects."1.48Mangiferin Potentiates Neuroprotection by Isoflurane in Neonatal Hypoxic Brain Injury by Reducing Oxidative Stress and Activation of Phosphatidylinositol-3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling. ( Long, XX; Ma, Y; Wang, YF; Xi, JS, 2018)
"In a brain slice model of cerebral anoxia, 1 minimum alveolar concentration isoflurane decreases glutamate release to a similar extent that hypothermia (28 degrees C) does."1.29Hypothermia and isoflurane similarly inhibit glutamate release evoked by chemical anoxia in rat cortical brain slices. ( Bickler, PE; Eilers, H, 1996)
"Isoflurane (1."1.27Anesthetic protection against anoxic damage in the rat hippocampal slice. ( Bendo, AA; Cottrell, JE; Kass, IS, 1987)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's2 (18.18)18.2507
2000's5 (45.45)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xi, JS1
Wang, YF1
Long, XX1
Ma, Y1
Johnsen, D1
Murphy, SJ1
Nishimaki, H1
Fukuda, S1
Ishimoto, M1
Mori, Y1
Eguchi, H1
Kokubun, S1
Fujihara, H1
Watanabe, H1
Abo, T1
Sasaki, R1
Hirota, K1
Roth, SH1
Yamazaki, M1
Wang, J1
Meng, F1
Cottrell, JE2
Kass, IS2
Hou, H1
Grinberg, OY1
Grinberg, SA1
Khan, N1
Dunn, JF1
Swartz, HM1
Eilers, H1
Bickler, PE1
Raley-Susman, KM1
Barnes, JR1
Kaja, J1
Hoffman, WE1
Wheeler, P1
Edelman, G1
Charbel, FT1
Torres, NJ1
Ausman, JI1
Enlund, M1
Ahlstedt, B1
Revenäs, B1
Krekmanov, L1
Ronquist, G1
Bendo, AA1

Trials

1 trial available for isoflurane and Anoxia, Brain

ArticleYear
Hypoxic brain tissue following subarachnoid hemorrhage.
    Anesthesiology, 2000, Volume: 92, Issue:2

    Topics: Adult; Aged; Anesthetics, Inhalation; Body Temperature; Brain Chemistry; Carbon Dioxide; Desflurane;

2000

Other Studies

10 other studies available for isoflurane and Anoxia, Brain

ArticleYear
Mangiferin Potentiates Neuroprotection by Isoflurane in Neonatal Hypoxic Brain Injury by Reducing Oxidative Stress and Activation of Phosphatidylinositol-3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Oct-19, Volume: 24

    Topics: Animals; Antioxidants; Hypoxia; Hypoxia-Ischemia, Brain; Hypoxia, Brain; Isoflurane; Neuroprotection

2018
Isoflurane preconditioning protects neurons from male and female mice against oxygen and glucose deprivation and is modulated by estradiol only in neurons from female mice.
    Neuroscience, 2011, Dec-29, Volume: 199

    Topics: Animals; Brain Ischemia; Cell Survival; Estradiol; Estrogen Antagonists; Female; Glucose; Hypoxia, B

2011
Isoflurane ameliorates the posthypoxic deoxygenation of the rat brain--the role of cell adhesion molecules of polymorphonuclear leukocytes.
    Resuscitation, 2002, Volume: 54, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Brain; CD11b Antigen; Cerebrovascular Circulation; Electroencephal

2002
Anoxic depolarization of rat hippocampal slices is prevented by thiopental but not by propofol or isoflurane.
    British journal of anaesthesia, 2005, Volume: 94, Issue:4

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Evoked

2005
The differential effects of volatile anesthetics on electrophysiological and biochemical changes during and recovery after hypoxia in rat hippocampal slice CA1 pyramidal cells.
    Neuroscience, 2006, Jul-07, Volume: 140, Issue:3

    Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Calcium; Calcium Signaling; Cations; Cytop

2006
Cerebral PtO2, acute hypoxia, and volatile anesthetics in the rat brain.
    Advances in experimental medicine and biology, 2005, Volume: 566

    Topics: Anesthetics, Inhalation; Animals; Brain; Electron Spin Resonance Spectroscopy; Halothane; Hypoxia, B

2005
Hypothermia and isoflurane similarly inhibit glutamate release evoked by chemical anoxia in rat cortical brain slices.
    Anesthesiology, 1996, Volume: 85, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Cerebral Cortex; Dose-Response Relationship, Drug;

1996
Effects of volatile anesthetics on hippocampal slice metabolism, response to anoxia with and without glucose.
    Brain research, 1997, Apr-25, Volume: 755, Issue:1

    Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Energy Metabolism; Ether; Glucose; Halothane

1997
Adverse effects on the brain in connection with isoflurane-induced hypotensive anaesthesia.
    Acta anaesthesiologica Scandinavica, 1989, Volume: 33, Issue:5

    Topics: Adenylate Kinase; Adult; Aged; Female; Humans; Hypotension, Controlled; Hypoxia, Brain; Isoflurane;

1989
Anesthetic protection against anoxic damage in the rat hippocampal slice.
    Brain research, 1987, Feb-10, Volume: 403, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Evoked Potentials; Hippocampus; Hypoxia, Brain; In Vitro

1987