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isoflurane and Amyloid Deposits

isoflurane has been researched along with Amyloid Deposits in 4 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Research Excerpts

ExcerptRelevanceReference
" Furthermore, the commonly used isoflurane anesthesia induces vasodilation and is thereby inherently a vascular challenge."3.91Longitudinal assessment of cerebral perfusion and vascular response to hypoventilation in a bigenic mouse model of Alzheimer's disease with amyloid and tau pathology. ( Borghgraef, P; Dresselaers, T; Govaerts, K; Himmelreich, U; Kremer, A; Lechat, B; Struys, T; Van Leuven, F, 2019)
"Many in vitro findings suggest that isoflurane exposure might accelerate the process of Alzheimer Disease (AD); however, no behavioral evidence exists to support this theory."3.78Isoflurane exposure during mid-adulthood attenuates age-related spatial memory impairment in APP/PS1 transgenic mice. ( Chen, J; Chen, X; Su, D; Wang, B; Wang, X; Xu, H; Zhao, Y, 2012)
"Cotreatment with trehalose reduces the levels of β amyloid peptide aggregates, tau plaques and levels of phospho-tau."1.38Trehalose protects from aggravation of amyloid pathology induced by isoflurane anesthesia in APP(swe) mutant mice. ( Casarejos, MJ; de Yébenes, JG; Gomez, A; Mena, MA; Perucho, J; Solano, RM, 2012)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Hofmann, C1
Sander, A1
Wang, XX1
Buerge, M1
Jungwirth, B1
Borgstedt, L1
Kreuzer, M1
Kopp, C1
Schorpp, K1
Hadian, K1
Wotjak, CT1
Ebert, T1
Ruitenberg, M1
Parsons, CG1
Rammes, G1
Govaerts, K1
Lechat, B1
Struys, T1
Kremer, A1
Borghgraef, P1
Van Leuven, F1
Himmelreich, U1
Dresselaers, T1
Perucho, J1
Casarejos, MJ1
Gomez, A1
Solano, RM1
de Yébenes, JG1
Mena, MA1
Su, D1
Zhao, Y1
Xu, H1
Wang, B1
Chen, X1
Chen, J1
Wang, X1

Other Studies

4 other studies available for isoflurane and Amyloid Deposits

ArticleYear
Inhalational Anesthetics Do Not Deteriorate Amyloid-β-Derived Pathophysiology in Alzheimer's Disease: Investigations on the Molecular, Neuronal, and Behavioral Level.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 84, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Disease Models, Animal;

2021
Longitudinal assessment of cerebral perfusion and vascular response to hypoventilation in a bigenic mouse model of Alzheimer's disease with amyloid and tau pathology.
    NMR in biomedicine, 2019, Volume: 32, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Anesthesia; Animals; Brain; Carbon Dioxide; Disea

2019
Trehalose protects from aggravation of amyloid pathology induced by isoflurane anesthesia in APP(swe) mutant mice.
    Current Alzheimer research, 2012, Volume: 9, Issue:3

    Topics: Alzheimer Disease; Anesthetics, Inhalation; Animals; Disease Models, Animal; Female; Humans; Isoflur

2012
Isoflurane exposure during mid-adulthood attenuates age-related spatial memory impairment in APP/PS1 transgenic mice.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Anesthetics, Inhalation; Animals; Di

2012