isoflurane has been researched along with Amnesia in 11 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixty adult patients were assigned to one of 3 groups according to the anesthetic technique chosen: isolfurane inhalation, propofol infusion at a higher rate, and propofol infusion at a lower rate supplemented with epidural anesthesia." | 9.08 | [Comparison of the amnesic effects of propofol and isoflurane anesthesia]. ( Maeshima, K; Ono, K, 1998) |
| "Sixty adult patients were assigned to one of 3 groups according to the anesthetic technique chosen: isolfurane inhalation, propofol infusion at a higher rate, and propofol infusion at a lower rate supplemented with epidural anesthesia." | 5.08 | [Comparison of the amnesic effects of propofol and isoflurane anesthesia]. ( Maeshima, K; Ono, K, 1998) |
| "100 μM isoflurane (approximately EC50,amnesia) slowed fast- and slow-inhibitory postsynaptic current decay by approximately 25%." | 3.78 | Isoflurane enhances both fast and slow synaptic inhibition in the hippocampus at amnestic concentrations. ( Dai, S; Pearce, RA; Perouansky, M, 2012) |
| "In this study, we used a GABA(A) alpha4 receptor knockout mouse line to evaluate the contribution of alpha4-containing GABA(A)-Rs to the effects of immobility, hypnosis, and amnesia produced by isoflurane." | 3.75 | Gamma-aminobutyric acid type A receptor alpha 4 subunit knockout mice are resistant to the amnestic effect of isoflurane. ( Chandra, D; Eger, EI; Fanselow, MS; Harrison, N; Homanics, GE; Iyer, SV; Oh, I; Rau, V; Sonner, JM, 2009) |
| "Thirteen adult rats were implanted with multichannel depth electrodes to measure the microelectroencephalogram and were exposed to a range of concentrations of isoflurane and F6 spanning the concentrations that produce amnesia." | 3.74 | Amnesic concentrations of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N) and isoflurane alter hippocampal theta oscillations in vivo. ( Hentschke, H; Pearce, RA; Perkins, M; Perouansky, M, 2007) |
| "The results of the present study indicate that beta3-containing gamma-aminobutyric acidA receptors do not mediate the amnesia produced by isoflurane and do not mediate, or only partially mediate, the immobility produced by inhaled anesthetics." | 3.73 | Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane. ( Borghese, CM; Eger, EI; Harris, RA; Jurd, R; Laster, MJ; Liao, M; Rudolph, U; Sonner, JM, 2005) |
| "Isoflurane anaesthesia was proposed instead of electro-convulsive therapy (ECT) in patients with treatment-refractory depression." | 1.29 | Intra-individual open comparison of burst-suppression-isoflurane-anaesthesia versus electroconvulsive therapy in the treatment of severe depression. ( Carl, G; Engelhardt, W; Hartung, E, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eckle, VS | 1 |
| Hucklenbruch, C | 1 |
| Todorovic, SM | 1 |
| Rau, V | 2 |
| Iyer, SV | 1 |
| Oh, I | 2 |
| Chandra, D | 1 |
| Harrison, N | 1 |
| Eger, EI | 3 |
| Fanselow, MS | 2 |
| Homanics, GE | 2 |
| Sonner, JM | 3 |
| Liao, M | 2 |
| Bodarky, C | 1 |
| Dai, S | 1 |
| Perouansky, M | 3 |
| Pearce, RA | 3 |
| Fidalgo, AR | 1 |
| Cibelli, M | 1 |
| White, JP | 1 |
| Nagy, I | 1 |
| Wan, Y | 1 |
| Ma, D | 1 |
| Rinehart, JB | 1 |
| Baker, B | 1 |
| Raphael, D | 1 |
| Jurd, R | 1 |
| Rudolph, U | 1 |
| Borghese, CM | 1 |
| Harris, RA | 1 |
| Laster, MJ | 1 |
| Hentschke, H | 1 |
| Perkins, M | 1 |
| Engelhardt, W | 1 |
| Carl, G | 1 |
| Hartung, E | 1 |
| Ono, K | 1 |
| Maeshima, K | 1 |
1 review available for isoflurane and Amnesia
| Article | Year |
|---|---|
[What do we know about anesthetic mechanisms?: hypnosis, unresponsiveness to surgical incision and amnesia].
Topics: Amnesia; Anesthesia; Anesthetics; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, I | 2009 |
1 trial available for isoflurane and Amnesia
| Article | Year |
|---|---|
[Comparison of the amnesic effects of propofol and isoflurane anesthesia].
Topics: Adult; Amnesia; Anesthesia; Anesthesia Recovery Period; Anesthesia, Epidural; Female; Humans; Isoflu | 1998 |
9 other studies available for isoflurane and Amnesia
| Article | Year |
|---|---|
Gamma-aminobutyric acid type A receptor alpha 4 subunit knockout mice are resistant to the amnestic effect of isoflurane.
Topics: Amnesia; Anesthetics, Inhalation; Animals; Behavior, Animal; Conditioning, Psychological; Dose-Respo | 2009 |
Gamma-aminobutyric acid type A receptor β3 subunit forebrain-specific knockout mice are resistant to the amnestic effect of isoflurane.
Topics: Amnesia; Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Behavior, | 2011 |
Isoflurane enhances both fast and slow synaptic inhibition in the hippocampus at amnestic concentrations.
Topics: Amnesia; Animals; Cells, Cultured; Hippocampus; Inhibitory Postsynaptic Potentials; Isoflurane; Mice | 2012 |
Isoflurane causes neocortical but not hippocampal-dependent memory impairment in mice.
Topics: Amnesia; Anesthetics, Inhalation; Animals; Behavior, Animal; Buprenorphine; Conditioning, Operant; E | 2012 |
Postoperative global amnesia reversed with flumazenil.
Topics: Amnesia; Analgesics; Anesthesia, General; Cholangiopancreatography, Endoscopic Retrograde; Desfluran | 2012 |
Effects on synaptic inhibition in the hippocampus do not underlie the amnestic and convulsive properties of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane.
Topics: Amnesia; Anesthetics, Inhalation; Animals; Chromatography, Gas; Cyclobutanes; Electrophysiology; Exc | 2004 |
Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane.
Topics: Acoustic Stimulation; Amnesia; Anesthetics; Anesthetics, Inhalation; Animals; Behavior, Animal; Cond | 2005 |
Amnesic concentrations of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N) and isoflurane alter hippocampal theta oscillations in vivo.
Topics: Amnesia; Anesthetics, Inhalation; Animals; Behavior, Animal; Cyclobutanes; Electroencephalography; E | 2007 |
Intra-individual open comparison of burst-suppression-isoflurane-anaesthesia versus electroconvulsive therapy in the treatment of severe depression.
Topics: Adult; Aged; Amnesia; Anesthesia, Inhalation; Antidepressive Agents; Arrhythmias, Cardiac; Bipolar D | 1993 |