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isoflurane and Amnesia-Memory Loss

isoflurane has been researched along with Amnesia-Memory Loss in 11 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Research Excerpts

ExcerptRelevanceReference
"Sixty adult patients were assigned to one of 3 groups according to the anesthetic technique chosen: isolfurane inhalation, propofol infusion at a higher rate, and propofol infusion at a lower rate supplemented with epidural anesthesia."9.08[Comparison of the amnesic effects of propofol and isoflurane anesthesia]. ( Maeshima, K; Ono, K, 1998)
"Sixty adult patients were assigned to one of 3 groups according to the anesthetic technique chosen: isolfurane inhalation, propofol infusion at a higher rate, and propofol infusion at a lower rate supplemented with epidural anesthesia."5.08[Comparison of the amnesic effects of propofol and isoflurane anesthesia]. ( Maeshima, K; Ono, K, 1998)
"100 μM isoflurane (approximately EC50,amnesia) slowed fast- and slow-inhibitory postsynaptic current decay by approximately 25%."3.78Isoflurane enhances both fast and slow synaptic inhibition in the hippocampus at amnestic concentrations. ( Dai, S; Pearce, RA; Perouansky, M, 2012)
"In this study, we used a GABA(A) alpha4 receptor knockout mouse line to evaluate the contribution of alpha4-containing GABA(A)-Rs to the effects of immobility, hypnosis, and amnesia produced by isoflurane."3.75Gamma-aminobutyric acid type A receptor alpha 4 subunit knockout mice are resistant to the amnestic effect of isoflurane. ( Chandra, D; Eger, EI; Fanselow, MS; Harrison, N; Homanics, GE; Iyer, SV; Oh, I; Rau, V; Sonner, JM, 2009)
"Thirteen adult rats were implanted with multichannel depth electrodes to measure the microelectroencephalogram and were exposed to a range of concentrations of isoflurane and F6 spanning the concentrations that produce amnesia."3.74Amnesic concentrations of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N) and isoflurane alter hippocampal theta oscillations in vivo. ( Hentschke, H; Pearce, RA; Perkins, M; Perouansky, M, 2007)
"The results of the present study indicate that beta3-containing gamma-aminobutyric acidA receptors do not mediate the amnesia produced by isoflurane and do not mediate, or only partially mediate, the immobility produced by inhaled anesthetics."3.73Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane. ( Borghese, CM; Eger, EI; Harris, RA; Jurd, R; Laster, MJ; Liao, M; Rudolph, U; Sonner, JM, 2005)
"Isoflurane anaesthesia was proposed instead of electro-convulsive therapy (ECT) in patients with treatment-refractory depression."1.29Intra-individual open comparison of burst-suppression-isoflurane-anaesthesia versus electroconvulsive therapy in the treatment of severe depression. ( Carl, G; Engelhardt, W; Hartung, E, 1993)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's5 (45.45)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eckle, VS1
Hucklenbruch, C1
Todorovic, SM1
Rau, V2
Iyer, SV1
Oh, I2
Chandra, D1
Harrison, N1
Eger, EI3
Fanselow, MS2
Homanics, GE2
Sonner, JM3
Liao, M2
Bodarky, C1
Dai, S1
Perouansky, M3
Pearce, RA3
Fidalgo, AR1
Cibelli, M1
White, JP1
Nagy, I1
Wan, Y1
Ma, D1
Rinehart, JB1
Baker, B1
Raphael, D1
Jurd, R1
Rudolph, U1
Borghese, CM1
Harris, RA1
Laster, MJ1
Hentschke, H1
Perkins, M1
Engelhardt, W1
Carl, G1
Hartung, E1
Ono, K1
Maeshima, K1

Reviews

1 review available for isoflurane and Amnesia-Memory Loss

ArticleYear
[What do we know about anesthetic mechanisms?: hypnosis, unresponsiveness to surgical incision and amnesia].
    Der Anaesthesist, 2009, Volume: 58, Issue:11

    Topics: Amnesia; Anesthesia; Anesthetics; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, I

2009

Trials

1 trial available for isoflurane and Amnesia-Memory Loss

ArticleYear
[Comparison of the amnesic effects of propofol and isoflurane anesthesia].
    Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:7

    Topics: Adult; Amnesia; Anesthesia; Anesthesia Recovery Period; Anesthesia, Epidural; Female; Humans; Isoflu

1998

Other Studies

9 other studies available for isoflurane and Amnesia-Memory Loss

ArticleYear
Gamma-aminobutyric acid type A receptor alpha 4 subunit knockout mice are resistant to the amnestic effect of isoflurane.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:6

    Topics: Amnesia; Anesthetics, Inhalation; Animals; Behavior, Animal; Conditioning, Psychological; Dose-Respo

2009
Gamma-aminobutyric acid type A receptor β3 subunit forebrain-specific knockout mice are resistant to the amnestic effect of isoflurane.
    Anesthesia and analgesia, 2011, Volume: 113, Issue:3

    Topics: Amnesia; Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Behavior,

2011
Isoflurane enhances both fast and slow synaptic inhibition in the hippocampus at amnestic concentrations.
    Anesthesiology, 2012, Volume: 116, Issue:4

    Topics: Amnesia; Animals; Cells, Cultured; Hippocampus; Inhibitory Postsynaptic Potentials; Isoflurane; Mice

2012
Isoflurane causes neocortical but not hippocampal-dependent memory impairment in mice.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8

    Topics: Amnesia; Anesthetics, Inhalation; Animals; Behavior, Animal; Buprenorphine; Conditioning, Operant; E

2012
Postoperative global amnesia reversed with flumazenil.
    The neurologist, 2012, Volume: 18, Issue:4

    Topics: Amnesia; Analgesics; Anesthesia, General; Cholangiopancreatography, Endoscopic Retrograde; Desfluran

2012
Effects on synaptic inhibition in the hippocampus do not underlie the amnestic and convulsive properties of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane.
    Anesthesiology, 2004, Volume: 101, Issue:1

    Topics: Amnesia; Anesthetics, Inhalation; Animals; Chromatography, Gas; Cyclobutanes; Electrophysiology; Exc

2004
Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:2

    Topics: Acoustic Stimulation; Amnesia; Anesthetics; Anesthetics, Inhalation; Animals; Behavior, Animal; Cond

2005
Amnesic concentrations of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N) and isoflurane alter hippocampal theta oscillations in vivo.
    Anesthesiology, 2007, Volume: 106, Issue:6

    Topics: Amnesia; Anesthetics, Inhalation; Animals; Behavior, Animal; Cyclobutanes; Electroencephalography; E

2007
Intra-individual open comparison of burst-suppression-isoflurane-anaesthesia versus electroconvulsive therapy in the treatment of severe depression.
    European journal of anaesthesiology, 1993, Volume: 10, Issue:2

    Topics: Adult; Aged; Amnesia; Anesthesia, Inhalation; Antidepressive Agents; Arrhythmias, Cardiac; Bipolar D

1993