Page last updated: 2024-10-29

isoflurane and Airway Obstruction

isoflurane has been researched along with Airway Obstruction in 11 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.

Research Excerpts

Excerpt	Relevance	Reference
" We conclude that the laryngeal mask provides a safe and effective form of airway management for infants and children in the hands of supervised anaesthesia trainees both for spontaneous and controlled ventilation using either isoflurane or total intravenous anaesthesia."	2.68	Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children. ( Alvarez, M; Brimacombe, J; Lopez-Gil, M, 1996)
"Six episodes of coughing and hiccoughs occurred after the end of anesthesia."	1.29	Desflurane and the sensitivity of upper airway reflexes. ( Park, GR, 1995)

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (9.09)	18.7374
1990's	4 (36.36)	18.2507
2000's	4 (36.36)	29.6817
2010's	2 (18.18)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Drummond, GB	2
Dhonneur, G	2
Kirov, K	2
Duvaldestin, P	2
Eastwood, PR	1
Szollosi, I	1
Platt, PR	1
Hillman, DR	1
Dahlgren, G	1
Törnberg, DC	1
Pregner, K	1
Irestedt, L	1
Hirshman, CA	1
Edelstein, G	1
Peetz, S	1
Wayne, R	1
Downes, H	1
Park, GR	1
Lopez-Gil, M	1
Brimacombe, J	1
Alvarez, M	1
Nehashi, S	1
Nishino, T	1
Ide, T	1
Good, DA	1
Heatley, JJ	1
Tully, TN	1
Smith, JA	1
Bailey, AG	1
Valley, RD	1
Azizkhan, RG	1
Wood, RE	1
Lewis, IH	1

Clinical Trials (4)

Trial Overview

Trial	Enrollment	Study Type	Start Date	Status
Tematic Evaluation of a New Medical Device (STAIRWAY) for Open Airways[NCT05708651]	56 participants (Anticipated)	Interventional	2023-02-28	Not yet recruiting
A Comparison of Different Ventilation Strategies in Children Using the Proseal™ Laryngeal Mask Airway[NCT00966433]	33 participants (Actual)	Interventional	2009-08-31	Completed
The Safety and Efficacy of Supraglottic Airway Use in Children[NCT02202174]	10,000 participants (Anticipated)	Observational	2014-06-30	Recruiting
Comparison of Weight-based Versus External Ear-size Based Technique for Selection of Laryngeal Mask Airway in Pediatric Surgical Patients.[NCT03931122]	136 participants (Anticipated)	Interventional	2019-12-11	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Differences in End-tidal Carbon Dioxide Compared Between the Spontaneous Ventilation and Pressure Support Ventilation Groups.

Differences in End-tidal Carbon Dioxide Compared Between the Spontaneous Ventilation and Pressure Support Ventilation Groups will be calculated by subtracting the mean of End-tidal Carbon Dioxide from the PSV group to the SV group (NCT00966433)
Timeframe: up to 90 minutes

Intervention	mmHg (Mean)
Spontaneous Ventilation	55.2
Pressure Support Ventilation	47

Differences in Respiratory Rates Between Spontaneous Ventilation and Pressure Support Ventilation Groups.

Differences in respiratory rates between spontaneous ventilation and pressure support ventilation groups will be calculated by subtracting the mean of from the respiratory rates PSV group to the SV group. (NCT00966433)
Timeframe: up to 90 minutes

Intervention	breath/min (Mean)
Spontaneous Ventilation	28.1
Pressure Support Ventilation	14.2

Differences Tidal Volume Compared Between the Spontaneous Ventilation and Pressure Support Ventilation Groups.

Tidal Volume Compared Between the Spontaneous Ventilation and Pressure Support Ventilation Groups. Measured in mL/Kg and will be calculated by subtracting the mean of tidal volume from the PSV group to the SV group (NCT00966433)
Timeframe: up to 90 minutes

Intervention	mL/kg (Mean)
Spontaneous Ventilation	4.0
Pressure Support Ventilation	7.6

Mean Tidal Volume Values Compared Between SV and PCV Groups

Mean Tidal Volume Values compared between SV and PCV Groups. Measured in mL/kg (NCT00966433)
Timeframe: up to 90 minutes

Intervention	mL/kg (Mean)
Spontaneous Ventilation	4.0
Pressure Control Ventilation	7.6

Mean Values of ETCO2 Between the PSV and PCV Groups

Mean Values of ETCO2 between the PSV and PCV Groups. Measured in mmHg (NCT00966433)
Timeframe: up to 90 minutes

Intervention	mmHg (Mean)
Pressure Support Ventilation	47.0
Pressure Control Ventilation	43.1

Mean Values of ETCO2 in SV and PCV Groups

Mean Values of ETCO2 in SV and PCV groups reported in mmHg (NCT00966433)
Timeframe: up to 90 minutes

Intervention	mmHg (Mean)
Spontaneous Ventilation	55.2
Pressure Control Ventilation	43.1

Mean Values of Respiratory Rate Compared Between Pressure Support Ventilation and Pressure Control Ventilation Groups.

(NCT00966433)
Timeframe: up to 90 minutes

Intervention	breath/min (Mean)
Pressure Support Ventilation	14.2
Pressure Control Ventilation	21.2

Mean Values of Respiratory Rate Compared Between the Spontaneous Ventilation and Pressure Control Ventilation Groups.

(NCT00966433)
Timeframe: up to 90 minutes

Intervention	breath/min (Mean)
Spontaneous Ventilation	28.1
Pressure Control Ventilation	21.2

Mean Values of Tidal Volume Between the PSV and PCV Groups

Mean Values of Tidal Volume Between the PSV and PCV Groups. Measured in mL/kg (NCT00966433)
Timeframe: up to 90 minutes

Intervention	mL/kg (Mean)
Pressure Support Ventilation	7.6
Pressure Control Ventilation	7.6

Trials

2 trials available for isoflurane and Airway Obstruction

Article	Year
Collapsibility of the upper airway during anesthesia with isoflurane. Anesthesiology, 2002, Volume: 97, Issue:4 Topics: Adult; Air Pressure; Airway Obstruction; Anesthesia, Inhalation; Anesthetics, Inhalation; Biomechani	2002
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children. Anaesthesia, 1996, Volume: 51, Issue:10 Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant	1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children. Anaesthesia, 1996, Volume: 51, Issue:10 Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant	1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children. Anaesthesia, 1996, Volume: 51, Issue:10 Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant	1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children. Anaesthesia, 1996, Volume: 51, Issue:10 Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant	1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children. Anaesthesia, 1996, Volume: 51, Issue:10 Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant	1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children. Anaesthesia, 1996, Volume: 51, Issue:10 Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant	1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children. Anaesthesia, 1996, Volume: 51, Issue:10 Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant	1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children. Anaesthesia, 1996, Volume: 51, Issue:10 Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant	1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children. Anaesthesia, 1996, Volume: 51, Issue:10 Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant	1996

Other Studies

9 other studies available for isoflurane and Airway Obstruction

Article	Year
Effects of airway occlusion on breathing muscle electromyogram signals, during isoflurane anaesthesia, with and without the effects of fentanyl and hypercapnia. British journal of anaesthesia, 2011, Volume: 107, Issue:6 Topics: Abdominal Muscles; Adult; Aged; Airway Obstruction; Analgesics, Opioid; Anesthetics, Inhalation; Car	2011
Effects of an opioid on respiratory movements and expiratory activity in humans during isoflurane anaesthesia. Respiratory physiology & neurobiology, 2013, Jan-15, Volume: 185, Issue:2 Topics: Abdominal Muscles; Adult; Airway Obstruction; Airway Resistance; Analgesics, Opioid; Anesthetics, In	2013
Four cases of the ex utero intrapartum treatment (EXIT) procedure: anesthetic implications. International journal of obstetric anesthesia, 2004, Volume: 13, Issue:3 Topics: Adult; Airway Obstruction; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics, Inhalation;	2004
Mechanism of action of inhalational anesthesia on airways. Anesthesiology, 1982, Volume: 56, Issue:2 Topics: Airway Obstruction; Airway Resistance; Anesthesia, Inhalation; Animals; Dogs; Halothane; Isoflurane;	1982
Desflurane and the sensitivity of upper airway reflexes. Middle East journal of anaesthesiology, 1995, Volume: 13, Issue:3 Topics: Adult; Airway Obstruction; Anesthetics, Inhalation; Child; Cough; Desflurane; Female; Hiccup; Humans	1995
Inhaled furosemide inhibits behavioral response to airway occlusion in anesthetized cats. Anesthesiology, 2001, Volume: 95, Issue:5 Topics: Administration, Inhalation; Airway Obstruction; Anesthesia, Inhalation; Animals; Cats; Diuretics; Fu	2001
Anesthesia case of the month. Partial obstruction of the trachea was a differential diagnosis for the bird's respiratory problems. Journal of the American Veterinary Medical Association, 2001, Dec-01, Volume: 219, Issue:11 Topics: Air Sacs; Airway Obstruction; Anesthesia; Animals; Bird Diseases; Diagnosis, Differential; Endoscopy	2001
Anaesthetic management of infants requiring endobronchial argon laser surgery. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:6 Topics: Airway Obstruction; Anesthesia, Endotracheal; Anesthesia, Inhalation; Argon; Bronchial Diseases; Bro	1992
Inhalation induction of anaesthesia with isoflurane in children. British journal of anaesthesia, 1991, Volume: 67, Issue:4 Topics: Airway Obstruction; Anesthesia, Inhalation; Child; Humans; Isoflurane	1991