isoflurane has been researched along with Aging in 127 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We asked whether the sympathomimetic effect of nitrous oxide (N2O) predisposed patients receiving N2O to arrhythmias in response to epinephrine administration." | 9.06 | Nitrous oxide and epinephrine-induced arrhythmias. ( Donegan, JH; Fouts, KE; Lampe, GH; Litt, LL; Rampil, IJ; Rose, BM; Rupp, SM; Wauk, LZ; Whitendale, P; Wilson, CB, 1990) |
| " To investigate the intervention of exogenous adiponectin in the elderly rats with cognitive dysfunction induced by isoflurane through mitogen-activated protein kinase (MAPK) signaling pathway in hippocampus." | 7.91 | Adiponectin improves isoflurane-induced cognitive dysfunction in elderly rats via inhibiting p38-MAPK signal pathway in hippocampus. ( Chen, BN; Luo, YP; Wang, X; Zhang, FX; Zhang, JC; Zhang, WJ; Zhao, Q, 2019) |
| "Mitochondrial dysfunction has been linked to the earliest pathogenesis of isoflurane-induced cognitive impairments in developing or aging mammalian brain." | 7.83 | BDNF pathway is involved in the protective effects of SS-31 on isoflurane-induced cognitive deficits in aging mice. ( Hao, S; Ji, M; Li, H; Li, K; Sun, X; Wu, J; Yang, J; Zhang, M, 2016) |
| " Therefore, the present study aimed to determine the neuroprotective effects of nobiletin, and to evaluate whether it could ameliorate isoflurane‑induced cognitive impairment via antioxidant, anti‑inflammatory and anti‑apoptotic effects in aging rats." | 7.83 | Nobiletin ameliorates isoflurane-induced cognitive impairment via antioxidant, anti-inflammatory and anti-apoptotic effects in aging rats. ( Bi, J; Lei, W; Lu, J; Zhang, H, 2016) |
| "Isoflurane possesses neurotoxicity and can induce cognitive deficits, particularly in aging mammals." | 7.81 | A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice. ( Hao, S; Ji, M; Li, H; Li, K; Sun, X; Wu, J; Yang, J; Zhang, H, 2015) |
| " The combined use of MS-222 with isoflurane effectively extended the time of anesthesia, and the zebrafish recovered faster than when anesthetized with the traditional MS-222." | 7.76 | Combined use of MS-222 (tricaine) and isoflurane extends anesthesia time and minimizes cardiac rhythm side effects in adult zebrafish. ( Chang, HW; Chen, IH; Chuang, YJ; Hsieh, YS; Huang, WC; Ku, TH; Wang, CH; Yang, CC; Yeh, SR, 2010) |
| "Melatonin has been considered as an effective remedy for circadian rhythm shift." | 5.48 | Circadian rhythm resynchronization improved isoflurane-induced cognitive dysfunction in aged mice. ( Chu, S; Cui, Y; Gu, X; Li, X; Ma, Z; Qian, Y; Shao, X; Song, J; Xia, T; Xu, F, 2018) |
| "We asked whether the sympathomimetic effect of nitrous oxide (N2O) predisposed patients receiving N2O to arrhythmias in response to epinephrine administration." | 5.06 | Nitrous oxide and epinephrine-induced arrhythmias. ( Donegan, JH; Fouts, KE; Lampe, GH; Litt, LL; Rampil, IJ; Rose, BM; Rupp, SM; Wauk, LZ; Whitendale, P; Wilson, CB, 1990) |
| "DUSP14 may effectively protect against isoflurane-induced neuro-inflammation, brain damage and cognitive dysfunction, indicating that DUSP14 may be a potential predictor and therapeutic target for POCD." | 3.96 | Neuroprotective effect of DUSP14 overexpression against isoflurane-induced inflammatory response, pyroptosis and cognitive impairment in aged rats through inhibiting the NLRP3 inflammasome. ( Peng, J; Que, YY; Zhang, FX; Zhu, T, 2020) |
| " To investigate the intervention of exogenous adiponectin in the elderly rats with cognitive dysfunction induced by isoflurane through mitogen-activated protein kinase (MAPK) signaling pathway in hippocampus." | 3.91 | Adiponectin improves isoflurane-induced cognitive dysfunction in elderly rats via inhibiting p38-MAPK signal pathway in hippocampus. ( Chen, BN; Luo, YP; Wang, X; Zhang, FX; Zhang, JC; Zhang, WJ; Zhao, Q, 2019) |
| "Isoflurane may not only accelerate the process of Alzheimer's disease (AD), but increase the risk of incidence of postoperative cognitive dysfunction (POCD)." | 3.88 | Isoflurane anesthesia in aged mice and effects of A1 adenosine receptors on cognitive impairment. ( Hao, XR; Lian, QQ; Lin, H; Liu, HC; Liu, J; Pan, YZ; Shen, T; Wang, CM; Zhou, JP; Zuo, CL, 2018) |
| " Isoflurane induced cognitive impairment and hippocampal inflammation in aged mice but not in young mice." | 3.88 | Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment. ( Cao, L; Chen, Y; Meng, S; Peng, S; Wang, Z; Zuo, Z, 2018) |
| "Mitochondrial dysfunction has been linked to the earliest pathogenesis of isoflurane-induced cognitive impairments in developing or aging mammalian brain." | 3.83 | BDNF pathway is involved in the protective effects of SS-31 on isoflurane-induced cognitive deficits in aging mice. ( Hao, S; Ji, M; Li, H; Li, K; Sun, X; Wu, J; Yang, J; Zhang, M, 2016) |
| "Although it is known that isoflurane exposure or surgery leads to post-operative cognitive dysfunction in aged rodents, there are few clinical interventions and treatments available to prevent this disorder." | 3.83 | Minocycline attenuates post-operative cognitive impairment in aged mice by inhibiting microglia activation. ( Fang, H; Liao, QW; Liu, H; Wang, HL; Xue, ZG, 2016) |
| " Therefore, the present study aimed to determine the neuroprotective effects of nobiletin, and to evaluate whether it could ameliorate isoflurane‑induced cognitive impairment via antioxidant, anti‑inflammatory and anti‑apoptotic effects in aging rats." | 3.83 | Nobiletin ameliorates isoflurane-induced cognitive impairment via antioxidant, anti-inflammatory and anti-apoptotic effects in aging rats. ( Bi, J; Lei, W; Lu, J; Zhang, H, 2016) |
| "Isoflurane possesses neurotoxicity and can induce cognitive deficits, particularly in aging mammals." | 3.81 | A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice. ( Hao, S; Ji, M; Li, H; Li, K; Sun, X; Wu, J; Yang, J; Zhang, H, 2015) |
| "Pretreatment with isoflurane decreased myocardial infarction size in young rats (3-5 months) but not in old rats (20-24 months)." | 3.76 | Age-associated differences in activation of Akt/GSK-3beta signaling pathways and inhibition of mitochondrial permeability transition pore opening in the rat heart. ( Brink, PR; Glass, PS; Liu, L; Rebecchi, MJ; Tan, M; Zhu, J, 2010) |
| " The combined use of MS-222 with isoflurane effectively extended the time of anesthesia, and the zebrafish recovered faster than when anesthetized with the traditional MS-222." | 3.76 | Combined use of MS-222 (tricaine) and isoflurane extends anesthesia time and minimizes cardiac rhythm side effects in adult zebrafish. ( Chang, HW; Chen, IH; Chuang, YJ; Hsieh, YS; Huang, WC; Ku, TH; Wang, CH; Yang, CC; Yeh, SR, 2010) |
| "The authors' study suggests that desflurane does not induce significant intramyocardial catecholamine release in senescent myocardium, a result that should be integrated in the well-known alteration in the catecholamine response during aging." | 3.73 | Effects of desflurane in senescent rat myocardium. ( Amour, J; Besse, S; Riou, B; Rozenberg, S; Tavernier, B; Vivien, B, 2006) |
| "To define the effect of aging on the pharmacokinetics of volatile anesthetics, we determined the end-tidal and mixed expired anesthetic concentrations of isoflurane, enflurane, halothane, and methoxyflurane during 30 min of simultaneous administration and for 5-12 days of elimination in seven healthy young patients (31 +/- 1." | 3.68 | Age affects the pharmacokinetics of inhaled anesthetics in humans. ( Carpenter, RL; Eger, EI; Johnson, BH; Strum, DP; Unadkat, JD, 1991) |
| "Additionally, trisomy 21 (P = 0." | 2.76 | Factors affecting the decision to defer endotracheal extubation after surgery for congenital heart disease: a prospective observational study. ( Bodian, C; Chakravarti, S; Hollinger, I; Hossain, S; Kin, N; Krol, M; Mittnacht, AJ; Nguyen, K; Srivastava, S; Weismann, C, 2011) |
| "Mivacurium was infused, targeting 90% twitch depression." | 2.69 | The pharmacokinetics and steady state pharmacodynamics of mivacurium in children. ( Brown, R; Fisher, DM; Lau, M; Luks, AM; Markakis, DA; Sharma, ML, 1998) |
| "Isoflurane did not produce any change in the degree of ischemia as judged from the ECG." | 2.66 | The influence of isoflurane on blood flow in coronary bypass grafts. ( Brodin, LA; Ekeström, S; Ohqvist, G; Settergren, G, 1985) |
| "Desflurane is a new volatile anaesthetic agent, with qualitative physiological and pharmacological effects similar to those of previously available drugs of this type." | 2.39 | Desflurane clinical pharmacokinetics and pharmacodynamics. ( Caldwell, JE, 1994) |
| "Sleep disorders, including sleep fragmentation, are reported to aggravate memory impairment in neurocognitive-related diseases such as Alzheimer's disease (AD)." | 1.91 | A modified mouse model of perioperative neurocognitive disorders exacerbated by sleep fragmentation. ( Cong, P; Huang, X; Li, M; Tian, L; Wu, H; Wu, T; Xiong, L; Zhang, H; Zhang, Q, 2023) |
| " The authors used the ND23 mutant for testing the hypothesis that anesthetics have toxic potential in carriers of mitochondrial mutations." | 1.56 | Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity. ( Ganetzky, B; Olufs, ZPG; Perouansky, M; Wassarman, DA, 2020) |
| "Isoflurane is a widely used anesthetic agent, which is associated with the development of POCD; however, the precise mechanisms remain unclear." | 1.56 | Effects of PYRIN-containing Apaf1-like protein 1 on isoflurane-induced postoperative cognitive dysfunction in aged rats. ( Fan, X; Li, F; Qiu, J; Zhang, X; Zhang, Y, 2020) |
| "Cognitive dysfunction is one of the most common postoperative complications experienced by older patients after anesthesia and surgery but the cause remains unknown." | 1.48 | Isoflurane anesthesia impairs the expression of immune neuromodulators in the hippocampus of aged mice. ( Crosby, G; Culley, DJ; Friese, MB; Nathan, M, 2018) |
| "Melatonin has been considered as an effective remedy for circadian rhythm shift." | 1.48 | Circadian rhythm resynchronization improved isoflurane-induced cognitive dysfunction in aged mice. ( Chu, S; Cui, Y; Gu, X; Li, X; Ma, Z; Qian, Y; Shao, X; Song, J; Xia, T; Xu, F, 2018) |
| "The incidence of post-anesthetic colic for this study population was 2." | 1.43 | Incidence of post-anesthetic colic in non-fasted adult equine patients. ( Bailey, PA; Brakenhoff, JE; Davis, M; Hague, BA; Major, MD; Zubrod, CJ, 2016) |
| "Taurine pretreatment dose-dependently inhibited isoflurane-induced increase in expression of ER stress biomarkers except for P-EIF2α and ATF-4, and reversed isoflurane-induced changes in apoptosis-related proteins." | 1.43 | Taurine Pretreatment Prevents Isoflurane-Induced Cognitive Impairment by Inhibiting ER Stress-Mediated Activation of Apoptosis Pathways in the Hippocampus in Aged Rats. ( Hou, D; Hou, J; Li, D; Li, H; Zhang, Y, 2016) |
| "When methylphenidate was administered after propofol, the mean time to emergence decreased to 6." | 1.42 | Ageing delays emergence from general anaesthesia in rats by increasing anaesthetic sensitivity in the brain. ( Brown, EN; Chemali, JJ; Kenny, JD; Kimchi, EY; Olutola, O; Purdon, PL; Solt, K; Taylor, NE, 2015) |
| "Increasingly more aged people with Alzheimer's disease (AD) must undergo surgery with general anesthesia for various reasons." | 1.40 | Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice. ( Deng, Y; He, Z; Lu, B; Qi, B; Su, D; Tian, J; Wang, X; Xu, H; Zheng, B, 2014) |
| "The isoflurane-exposed rats were further divided into a learning/memory-impaired subgroup and a non-learning/memory-impaired subgroup according to their behavioral performance, which was measured using Morris water maze." | 1.39 | Hippocampal glutamate level and glutamate aspartate transporter (GLAST) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment. ( Ji, C; Jia, X; Liu, W; Qu, X; Wang, H; Wang, Y; Wu, A; Xie, Z; Xu, C; Xu, J; Xu, Z; Yue, Y, 2013) |
| "Isoflurane may not cause long-lasting neuropathological changes." | 1.38 | Lidocaine attenuates cognitive impairment after isoflurane anesthesia in old rats. ( Cao, L; Li, J; Lin, D; Wang, Z; Washington, JM; Zuo, Z, 2012) |
| "Isoflurane has been shown to promote Alzheimer's disease neuropathogenesis." | 1.38 | Isoflurane-induced spatial memory impairment by a mechanism independent of amyloid-beta levels and tau protein phosphorylation changes in aged rats. ( Feng, C; Ji, C; Liu, W; Wang, H; Wang, Y; Wu, A; Xie, Z; Xu, C; Xu, J; Xu, Z; Yue, Y; Zhang, X, 2012) |
| "The isoflurane anaesthesia treatment increased the escape latency contrast to propofol anaesthesia group." | 1.38 | Changes of learning and memory in aged rats after isoflurane inhalational anaesthesia correlated with hippocampal acetylcholine level. ( Feng, C; Jia, X; Wang, H; Wang, Y; Wu, A; Xu, Z; Yue, Y, 2012) |
| "Isoflurane was administered to 16-month-old rats at one minimum alveolar concentration for 4 h." | 1.36 | Isoflurane does not affect brain cell death, hippocampal neurogenesis, or long-term neurocognitive outcome in aged rats. ( Alvi, RS; Bell, JS; Bickler, PE; Chiu, C; Dai, R; Dowlatshahi, M; Hrubos, MW; Ku, B; Lee, MT; May, Ld; Russell, I; Sall, JW; Stratmann, G, 2010) |
| "Isoflurane may cause the alteration of hippocampal proteome in rats, which is age-related." | 1.35 | [Delayed effect of isoflurane on hippocampal proteome after anesthesia in adult and aged rats]. ( Chen, M; Duan, K; Ouyang, W; Wang, S; Xia, Y, 2009) |
| " Plasma dilution data were derived from repeated sampling of hemoglobin concentration, and population pharmacokinetic analysis was conducted using the WinNonMix 2." | 1.34 | Population volume kinetics predicts retention of 0.9% saline infused in awake and isoflurane-anesthetized volunteers. ( Børsheim, E; Hahn, RG; Li, H; Minton, RK; Norberg, A; Olsson, J; Prough, DS; Svensén, CH; Wolf, S, 2007) |
| "Halothane induced a lower negative inotropic effect in senescent rats (1." | 1.31 | Myocardial effects of halothane and isoflurane in senescent rats. ( Besse, S; Coriat, P; Riou, B; Rozenberg, S; Vivien, B, 2002) |
| "The current results indicate that diabetic autonomic neuropathy is associated with more severe intraoperative hypothermia." | 1.31 | Patients with diabetic neuropathy are at risk of a greater intraoperative reduction in core temperature. ( Hoshino, T; Kitamura, A; Kon, T; Ogawa, R, 2000) |
| "Halothane was a more potent depressant of cardiac function than isoflurane and developmental differences were more evident with this agent." | 1.29 | Direct myocardial effects of halothane and isoflurane. Comparison between adult and infant rabbits. ( Bosnjak, ZJ; Kampine, JP; Mehner, RW; Palmisano, BW; Stowe, DF, 1994) |
| "Isoflurane is a safe and effective inhalation anesthetic for muskrats, although prolonged induction may limit its use in field studies." | 1.29 | Isoflurane as an inhalation anesthetic for muskrats (Ondatra zibethicus). ( Belant, JL, 1995) |
| " Elimination half-life (96 +/- 20 min) and clearance (2." | 1.28 | Pharmacokinetics and pharmacodynamics of doxacurium in young and elderly patients during isoflurane anesthesia. ( Ali, HH; Basta, SJ; Brady, KA; Dresner, DL; Embree, PB; Lai, AA; Savarese, JJ; Schwartz, AF; Wargin, WA, 1990) |
| "Bupivacaine was infused at a constant rate while the pigs' ECGs and EEGs were recorded." | 1.28 | Bupivacaine toxicity in young pigs is age-dependent and is affected by volatile anesthetics. ( Badgwell, JM; Heavner, JE; Kytta, J, 1990) |
| "Isoflurane concentration was determined by infrared analysis of expired gas collected from a Teflon catheter inserted through the endotracheal tube." | 1.28 | Electroencephalographic burst suppression in elderly and young patients anesthetized with isoflurane. ( Poppers, PJ; Schwartz, AE; Tuttle, RH, 1989) |
| "Desflurane appears to be a mild airway irritant but was well tolerated by all patients." | 1.28 | Clinical characteristics of desflurane in surgical patients: minimum alveolar concentration. ( Damask, MC; Eger, EI; Lockhart, SH; Peterson, N; Rampil, IJ; Weiskopf, RB; Yasuda, N; Zwass, MS, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (8.66) | 18.7374 |
| 1990's | 25 (19.69) | 18.2507 |
| 2000's | 27 (21.26) | 29.6817 |
| 2010's | 55 (43.31) | 24.3611 |
| 2020's | 9 (7.09) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, S | 2 |
| Liu, Y | 9 |
| Huang, S | 1 |
| Jin, F | 1 |
| Qi, F | 1 |
| Wu, T | 1 |
| Li, M | 1 |
| Tian, L | 1 |
| Cong, P | 1 |
| Huang, X | 3 |
| Wu, H | 1 |
| Zhang, Q | 5 |
| Zhang, H | 5 |
| Xiong, L | 1 |
| Joseph, DJ | 1 |
| Liu, C | 3 |
| Peng, J | 2 |
| Liang, G | 1 |
| Wei, H | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 8 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 6 |
| Wang, H | 6 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 5 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 6 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 5 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 4 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 4 |
| Sun, Q | 1 |
| Han, D | 2 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 5 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 5 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 8 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 2 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 4 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 9 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 3 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 3 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 3 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 8 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 11 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 6 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
| Zhu, X | 1 |
| Xu, H | 3 |
| Yang, G | 2 |
| Lin, Z | 1 |
| Salem, HF | 1 |
| Nafady, MM | 1 |
| Kharshoum, RM | 1 |
| Abd El-Ghafar, OA | 1 |
| Farouk, HO | 1 |
| Domiciano, D | 1 |
| Nery, FC | 1 |
| de Carvalho, PA | 1 |
| Prudente, DO | 1 |
| de Souza, LB | 1 |
| Chalfun-Júnior, A | 1 |
| Paiva, R | 1 |
| Marchiori, PER | 1 |
| Lu, M | 2 |
| An, Z | 1 |
| Jiang, J | 2 |
| Li, J | 8 |
| Du, S | 1 |
| Zhou, H | 1 |
| Cui, J | 1 |
| Wu, W | 1 |
| Song, J | 2 |
| Lian, Q | 1 |
| Uddin Ahmad, Z | 1 |
| Gang, DD | 1 |
| Konggidinata, MI | 1 |
| Gallo, AA | 1 |
| Zappi, ME | 1 |
| Yang, TWW | 1 |
| Johari, Y | 1 |
| Burton, PR | 1 |
| Earnest, A | 1 |
| Shaw, K | 1 |
| Hare, JL | 1 |
| Brown, WA | 1 |
| Kim, GA | 1 |
| Han, S | 1 |
| Choi, GH | 1 |
| Choi, J | 1 |
| Lim, YS | 1 |
| Gallo, A | 1 |
| Cancelli, C | 1 |
| Ceron, E | 1 |
| Covino, M | 1 |
| Capoluongo, E | 1 |
| Pocino, K | 1 |
| Ianiro, G | 1 |
| Cammarota, G | 1 |
| Gasbarrini, A | 1 |
| Montalto, M | 1 |
| Somasundar, Y | 1 |
| Lu, IC | 1 |
| Mills, MR | 1 |
| Qian, LY | 1 |
| Olivares, X | 1 |
| Ryabov, AD | 1 |
| Collins, TJ | 1 |
| Zhao, L | 1 |
| Doddipatla, S | 1 |
| Thomas, AM | 1 |
| Nikolayev, AA | 1 |
| Galimova, GR | 1 |
| Azyazov, VN | 1 |
| Mebel, AM | 1 |
| Kaiser, RI | 1 |
| Guo, S | 1 |
| Yang, P | 1 |
| Yu, X | 2 |
| Wu, Y | 2 |
| Yu, B | 2 |
| Han, B | 1 |
| George, MW | 1 |
| Moor, MB | 1 |
| Bonny, O | 1 |
| Langenberg, E | 1 |
| Paik, H | 1 |
| Smith, EH | 1 |
| Nair, HP | 1 |
| Hanke, I | 1 |
| Ganschow, S | 1 |
| Catalan, G | 1 |
| Domingo, N | 1 |
| Schlom, DG | 1 |
| Assefa, MK | 1 |
| Wu, G | 2 |
| Hayton, TW | 1 |
| Becker, B | 1 |
| Enikeev, D | 1 |
| Netsch, C | 1 |
| Gross, AJ | 1 |
| Laukhtina, E | 1 |
| Glybochko, P | 1 |
| Rapoport, L | 1 |
| Herrmann, TRW | 1 |
| Taratkin, M | 1 |
| Dai, W | 1 |
| Shi, J | 2 |
| Carreno, J | 1 |
| Kloner, RA | 1 |
| Pickersgill, NA | 1 |
| Vetter, JM | 1 |
| Kim, EH | 1 |
| Cope, SJ | 1 |
| Du, K | 1 |
| Venkatesh, R | 1 |
| Giardina, JD | 1 |
| Saad, NES | 1 |
| Bhayani, SB | 1 |
| Figenshau, RS | 1 |
| Eriksson, J | 1 |
| Landfeldt, E | 1 |
| Ireland, S | 1 |
| Jackson, C | 1 |
| Wyatt, E | 1 |
| Gaudig, M | 1 |
| Stancill, JS | 1 |
| Happ, JT | 1 |
| Broniowska, KA | 1 |
| Hogg, N | 1 |
| Corbett, JA | 1 |
| Tang, LF | 1 |
| Bi, YL | 1 |
| Fan, Y | 2 |
| Sun, YB | 1 |
| Wang, AL | 1 |
| Xiao, BH | 1 |
| Wang, LF | 1 |
| Qiu, SW | 1 |
| Guo, SW | 1 |
| Wáng, YXJ | 1 |
| Sun, J | 2 |
| Chu, S | 2 |
| Pan, Q | 1 |
| Li, D | 3 |
| Zheng, S | 2 |
| Ma, L | 4 |
| Wang, L | 3 |
| Hu, T | 1 |
| Wang, F | 2 |
| Han, Z | 1 |
| Yin, Z | 1 |
| Ge, X | 1 |
| Xie, K | 1 |
| Lei, P | 1 |
| Dias-Santagata, D | 1 |
| Lennerz, JK | 1 |
| Sadow, PM | 1 |
| Frazier, RP | 1 |
| Govinda Raju, S | 1 |
| Henry, D | 1 |
| Chung, T | 1 |
| Kherani, J | 1 |
| Rothenberg, SM | 1 |
| Wirth, LJ | 1 |
| Marti, CN | 1 |
| Choi, NG | 1 |
| Bae, SJ | 1 |
| Ni, L | 1 |
| Luo, X | 1 |
| Dai, T | 1 |
| Yang, Y | 3 |
| Lee, R | 1 |
| Fleischer, AS | 1 |
| Wemhoff, AP | 1 |
| Ford, CR | 1 |
| Kleppinger, EL | 1 |
| Helms, K | 1 |
| Bush, AA | 1 |
| Luna-Abanto, J | 1 |
| García Ruiz, L | 1 |
| Laura Martinez, J | 1 |
| Álvarez Larraondo, M | 1 |
| Villoslada Terrones, V | 1 |
| Dukic, L | 1 |
| Maric, N | 1 |
| Simundic, AM | 1 |
| Chogtu, B | 1 |
| Ommurugan, B | 1 |
| Thomson, SR | 1 |
| Kalthur, SG | 1 |
| Benidir, M | 1 |
| El Massoudi, S | 1 |
| El Ghadraoui, L | 1 |
| Lazraq, A | 1 |
| Benjelloun, M | 1 |
| Errachidi, F | 1 |
| Cassar, M | 1 |
| Law, AD | 1 |
| Chow, ES | 1 |
| Giebultowicz, JM | 1 |
| Kretzschmar, D | 1 |
| Salonurmi, T | 1 |
| Nabil, H | 1 |
| Ronkainen, J | 1 |
| Hyötyläinen, T | 1 |
| Hautajärvi, H | 1 |
| Savolainen, MJ | 1 |
| Tolonen, A | 1 |
| Orešič, M | 1 |
| Känsäkoski, P | 1 |
| Rysä, J | 1 |
| Hakkola, J | 1 |
| Hukkanen, J | 1 |
| Zhu, N | 1 |
| Li, Y | 5 |
| Du, Q | 1 |
| Hao, P | 1 |
| Cao, X | 1 |
| Li, CX | 1 |
| Zhao, S | 1 |
| Luo, XM | 1 |
| Feng, JX | 1 |
| Gonzalez-Cotto, M | 1 |
| Guo, L | 1 |
| Karwan, M | 1 |
| Sen, SK | 1 |
| Barb, J | 1 |
| Collado, CJ | 1 |
| Elloumi, F | 1 |
| Palmieri, EM | 1 |
| Boelte, K | 1 |
| Kolodgie, FD | 1 |
| Finn, AV | 1 |
| Biesecker, LG | 1 |
| McVicar, DW | 1 |
| Qu, F | 1 |
| Deng, Z | 1 |
| Xie, Y | 2 |
| Tang, J | 3 |
| Chen, Z | 2 |
| Luo, W | 1 |
| Xiong, D | 1 |
| Zhao, D | 1 |
| Fang, J | 1 |
| Zhou, Z | 1 |
| Niu, PP | 1 |
| Song, B | 1 |
| Xu, YM | 1 |
| Zhang, Z | 2 |
| Qiu, N | 1 |
| Yin, J | 1 |
| Zhang, J | 3 |
| Guo, W | 1 |
| Liu, M | 2 |
| Liu, T | 3 |
| Chen, D | 5 |
| Luo, K | 1 |
| He, Z | 3 |
| Zheng, G | 1 |
| Xu, F | 3 |
| Sun, W | 1 |
| Yin, F | 1 |
| van Hest, JCM | 1 |
| Du, L | 2 |
| Shi, X | 1 |
| Kang, S | 1 |
| Duan, W | 1 |
| Zhang, S | 2 |
| Feng, J | 2 |
| Qi, N | 1 |
| Shen, G | 1 |
| Ren, H | 1 |
| Shang, Q | 1 |
| Zhao, W | 2 |
| Yang, Z | 2 |
| Jiang, X | 2 |
| Alame, M | 1 |
| Cornillot, E | 1 |
| Cacheux, V | 1 |
| Tosato, G | 1 |
| Four, M | 1 |
| De Oliveira, L | 1 |
| Gofflot, S | 1 |
| Delvenne, P | 1 |
| Turtoi, E | 1 |
| Cabello-Aguilar, S | 1 |
| Nishiyama, M | 1 |
| Turtoi, A | 1 |
| Costes-Martineau, V | 1 |
| Colinge, J | 1 |
| Guo, Q | 1 |
| Quan, M | 1 |
| Dong, J | 1 |
| Bai, J | 1 |
| Han, R | 1 |
| Cai, Y | 1 |
| Lv, YQ | 1 |
| Chen, Q | 1 |
| Lyu, HD | 1 |
| Deng, L | 1 |
| Zhou, D | 1 |
| Xiao, X | 1 |
| De Langhe, S | 1 |
| Billadeau, DD | 1 |
| Lou, Z | 1 |
| Zhang, JS | 1 |
| Xue, Z | 1 |
| Shen, XD | 1 |
| Gao, F | 1 |
| Busuttil, RW | 1 |
| Kupiec-Weglinski, JW | 1 |
| Ji, H | 1 |
| Otano, I | 1 |
| Alvarez, M | 1 |
| Minute, L | 1 |
| Ochoa, MC | 1 |
| Migueliz, I | 1 |
| Molina, C | 1 |
| Azpilikueta, A | 1 |
| de Andrea, CE | 1 |
| Etxeberria, I | 1 |
| Sanmamed, MF | 1 |
| Teijeira, Á | 1 |
| Berraondo, P | 1 |
| Melero, I | 1 |
| Zhong, Z | 1 |
| Xie, X | 1 |
| Yu, Q | 1 |
| Zhou, C | 1 |
| Liu, W | 4 |
| Chen, W | 1 |
| Yin, Y | 1 |
| Li, CW | 1 |
| Hsu, JL | 1 |
| Zhou, Q | 1 |
| Hu, B | 1 |
| Fu, P | 1 |
| Atyah, M | 1 |
| Ma, Q | 2 |
| Xu, Y | 1 |
| Dong, Q | 1 |
| Hung, MC | 1 |
| Ren, N | 1 |
| Huang, P | 1 |
| Liao, R | 1 |
| Chen, X | 3 |
| Cao, Q | 1 |
| Yuan, X | 1 |
| Nie, W | 1 |
| Yang, J | 6 |
| Shao, B | 1 |
| Ma, X | 1 |
| Bi, Z | 1 |
| Liang, X | 1 |
| Tie, Y | 1 |
| Mo, F | 1 |
| Xie, D | 1 |
| Wei, Y | 1 |
| Wei, X | 2 |
| Dokla, EME | 1 |
| Fang, CS | 1 |
| Chu, PC | 1 |
| Chang, CS | 1 |
| Abouzid, KAM | 1 |
| Chen, CS | 1 |
| Blaszczyk, R | 1 |
| Brzezinska, J | 1 |
| Dymek, B | 1 |
| Stanczak, PS | 1 |
| Mazurkiewicz, M | 1 |
| Olczak, J | 1 |
| Nowicka, J | 1 |
| Dzwonek, K | 1 |
| Zagozdzon, A | 1 |
| Golab, J | 1 |
| Golebiowski, A | 1 |
| Xin, Z | 1 |
| Himmelbauer, MK | 1 |
| Jones, JH | 1 |
| Enyedy, I | 1 |
| Gilfillan, R | 1 |
| Hesson, T | 1 |
| King, K | 1 |
| Marcotte, DJ | 1 |
| Murugan, P | 1 |
| Santoro, JC | 1 |
| Gonzalez-Lopez de Turiso, F | 1 |
| Pedron, J | 1 |
| Boudot, C | 1 |
| Brossas, JY | 1 |
| Pinault, E | 1 |
| Bourgeade-Delmas, S | 1 |
| Sournia-Saquet, A | 1 |
| Boutet-Robinet, E | 1 |
| Destere, A | 1 |
| Tronnet, A | 1 |
| Bergé, J | 1 |
| Bonduelle, C | 1 |
| Deraeve, C | 1 |
| Pratviel, G | 1 |
| Stigliani, JL | 1 |
| Paris, L | 1 |
| Mazier, D | 1 |
| Corvaisier, S | 1 |
| Since, M | 1 |
| Malzert-Fréon, A | 1 |
| Wyllie, S | 1 |
| Milne, R | 1 |
| Fairlamb, AH | 1 |
| Valentin, A | 1 |
| Courtioux, B | 1 |
| Verhaeghe, P | 1 |
| Fang, X | 1 |
| Gao, M | 1 |
| Gao, H | 1 |
| Bi, W | 1 |
| Tang, H | 1 |
| Cui, Y | 2 |
| Zhang, L | 5 |
| Fan, H | 1 |
| Yu, H | 1 |
| Mathison, CJN | 1 |
| Chianelli, D | 1 |
| Rucker, PV | 1 |
| Nelson, J | 1 |
| Roland, J | 1 |
| Huang, Z | 2 |
| Xie, YF | 1 |
| Epple, R | 1 |
| Bursulaya, B | 1 |
| Lee, C | 1 |
| Gao, MY | 1 |
| Shaffer, J | 1 |
| Briones, S | 1 |
| Sarkisova, Y | 1 |
| Galkin, A | 1 |
| Li, N | 1 |
| Li, C | 2 |
| Hua, S | 1 |
| Kasibhatla, S | 1 |
| Kinyamu-Akunda, J | 1 |
| Kikkawa, R | 1 |
| Molteni, V | 1 |
| Tellew, JE | 1 |
| Jin, X | 1 |
| Pang, B | 1 |
| Liu, Q | 3 |
| Liu, X | 3 |
| Huang, Y | 2 |
| Josephine Fauci, A | 1 |
| Ma, Y | 1 |
| Soo Lee, M | 1 |
| Yuan, W | 1 |
| Gao, R | 1 |
| Qi, H | 1 |
| Zheng, W | 1 |
| Yang, F | 2 |
| Chua, H | 1 |
| Wang, K | 1 |
| Ou, Y | 1 |
| Huang, M | 1 |
| Zhu, Y | 1 |
| Yu, J | 1 |
| Tian, J | 2 |
| Zhao, M | 1 |
| Hu, J | 1 |
| Yao, C | 1 |
| Zhang, B | 1 |
| Usawachintachit, M | 1 |
| Tzou, DT | 1 |
| Washington, SL | 1 |
| Hu, W | 2 |
| Chi, T | 1 |
| Sorensen, MD | 1 |
| Bailey, MR | 1 |
| Hsi, RS | 1 |
| Cunitz, BW | 1 |
| Simon, J | 1 |
| Wang, YN | 1 |
| Dunmire, BL | 1 |
| Paun, M | 1 |
| Starr, F | 1 |
| Lu, W | 1 |
| Evan, AP | 1 |
| Harper, JD | 1 |
| Han, G | 1 |
| Rodrigues, AE | 1 |
| Fouladvand, F | 1 |
| Falahi, E | 1 |
| Asbaghi, O | 1 |
| Abbasnezhad, A | 1 |
| Anigboro, AA | 1 |
| Avwioroko, OJ | 1 |
| Cholu, CO | 1 |
| Sonei, A | 1 |
| Fazelipour, S | 1 |
| Kanaani, L | 1 |
| Jahromy, MH | 1 |
| Jo, K | 1 |
| Hong, KB | 1 |
| Suh, HJ | 1 |
| Park, JH | 1 |
| Shin, E | 1 |
| Park, E | 1 |
| Kouakou-Kouamé, CA | 1 |
| N'guessan, FK | 1 |
| Montet, D | 1 |
| Djè, MK | 1 |
| Kim, GD | 1 |
| González-Fernández, D | 1 |
| Pons, EDC | 1 |
| Rueda, D | 1 |
| Sinisterra, OT | 1 |
| Murillo, E | 1 |
| Scott, ME | 1 |
| Koski, KG | 1 |
| Shete, PB | 1 |
| Gonzales, R | 1 |
| Ackerman, S | 1 |
| Cattamanchi, A | 1 |
| Handley, MA | 1 |
| Li, XX | 1 |
| Xiao, SZ | 1 |
| Gu, FF | 1 |
| He, WP | 1 |
| Ni, YX | 1 |
| Han, LZ | 1 |
| Heffernan, JK | 1 |
| Valgepea, K | 1 |
| de Souza Pinto Lemgruber, R | 1 |
| Casini, I | 1 |
| Plan, M | 1 |
| Tappel, R | 1 |
| Simpson, SD | 1 |
| Köpke, M | 1 |
| Nielsen, LK | 1 |
| Marcellin, E | 1 |
| Cen, YK | 1 |
| Lin, JG | 1 |
| Wang, YL | 1 |
| Wang, JY | 1 |
| Liu, ZQ | 1 |
| Zheng, YG | 1 |
| Spirk, D | 1 |
| Noll, S | 1 |
| Burnier, M | 1 |
| Rimoldi, S | 1 |
| Noll, G | 1 |
| Sudano, I | 1 |
| Penzhorn, BL | 1 |
| Oosthuizen, MC | 1 |
| Kobos, LM | 1 |
| Alqatani, S | 1 |
| Ferreira, CR | 1 |
| Aryal, UK | 1 |
| Hedrick, V | 1 |
| Sobreira, TJP | 1 |
| Shannahan, JH | 1 |
| Gale, P | 1 |
| Singhroy, DN | 1 |
| MacLean, E | 1 |
| Kohli, M | 1 |
| Lessem, E | 1 |
| Branigan, D | 1 |
| England, K | 1 |
| Suleiman, K | 1 |
| Drain, PK | 1 |
| Ruhwald, M | 1 |
| Schumacher, S | 1 |
| Denkinger, CM | 1 |
| Waning, B | 1 |
| Van Gemert, W | 1 |
| Pai, M | 1 |
| Myers, RK | 1 |
| Bonsu, JM | 1 |
| Carey, ME | 1 |
| Yerys, BE | 1 |
| Mollen, CJ | 1 |
| Curry, AE | 1 |
| Douglas, TA | 1 |
| Alinezhadbalalami, N | 1 |
| Balani, N | 1 |
| Schmelz, EM | 1 |
| Davalos, RV | 1 |
| Kamaldinov, T | 1 |
| Erndt-Marino, J | 1 |
| Levin, M | 1 |
| Kaplan, DL | 1 |
| Hahn, MS | 1 |
| Heidarimoghadam, R | 1 |
| Farmany, A | 1 |
| Lee, JJ | 1 |
| Kang, J | 1 |
| Park, S | 1 |
| Cho, JH | 1 |
| Oh, S | 1 |
| Park, DJ | 1 |
| Perez-Maldonado, R | 1 |
| Cho, JY | 1 |
| Park, IH | 1 |
| Kim, HB | 1 |
| Song, M | 1 |
| Mfarrej, B | 1 |
| Jofra, T | 1 |
| Morsiani, C | 1 |
| Gagliani, N | 1 |
| Fousteri, G | 1 |
| Battaglia, M | 1 |
| Giuliano, C | 1 |
| Levinger, I | 1 |
| Vogrin, S | 1 |
| Neil, CJ | 1 |
| Allen, JD | 1 |
| Lv, Y | 1 |
| Yuan, R | 1 |
| Cai, B | 1 |
| Bahrami, B | 1 |
| Chowdhury, AH | 1 |
| Yang, C | 2 |
| Qiao, Q | 1 |
| Liu, SF | 1 |
| Zhang, WH | 1 |
| Kolano, L | 1 |
| Knappe, D | 1 |
| Volke, D | 1 |
| Sträter, N | 1 |
| Hoffmann, R | 1 |
| Coussens, M | 1 |
| Calders, P | 1 |
| Lapauw, B | 1 |
| Celie, B | 1 |
| Banica, T | 1 |
| De Wandele, I | 1 |
| Pacey, V | 1 |
| Malfait, F | 1 |
| Rombaut, L | 1 |
| Vieira, D | 1 |
| Angel, S | 1 |
| Honjol, Y | 1 |
| Gruenheid, S | 1 |
| Gbureck, U | 1 |
| Harvey, E | 1 |
| Merle, G | 1 |
| Seo, G | 1 |
| Lee, G | 1 |
| Kim, MJ | 1 |
| Baek, SH | 1 |
| Choi, M | 1 |
| Ku, KB | 1 |
| Lee, CS | 1 |
| Jun, S | 1 |
| Park, D | 1 |
| Kim, HG | 1 |
| Kim, SJ | 1 |
| Lee, JO | 1 |
| Kim, BT | 1 |
| Park, EC | 1 |
| Kim, SI | 1 |
| Ende, M | 1 |
| Kirkkala, T | 1 |
| Loitzenbauer, M | 1 |
| Talla, D | 1 |
| Wildner, M | 1 |
| Miletich, R | 1 |
| Criado, A | 1 |
| Lavela, P | 1 |
| Tirado, JL | 1 |
| Pérez-Vicente, C | 1 |
| Kang, D | 1 |
| Feng, D | 2 |
| Fang, Z | 1 |
| Wei, F | 1 |
| De Clercq, E | 1 |
| Pannecouque, C | 1 |
| Zhan, P | 1 |
| Guo, Y | 1 |
| Shen, Y | 1 |
| Wang, Q | 3 |
| Kawazoe, Y | 1 |
| Jena, P | 1 |
| Sun, Z | 1 |
| Li, Z | 9 |
| Liang, H | 1 |
| Xu, X | 1 |
| Ma, G | 1 |
| Huo, X | 1 |
| Church, JS | 1 |
| Chace-Donahue, F | 1 |
| Blum, JL | 1 |
| Ratner, JR | 1 |
| Zelikoff, JT | 1 |
| Schwartzer, JJ | 1 |
| Fiseha, T | 1 |
| Tamir, Z | 1 |
| Yao, W | 1 |
| Wang, P | 1 |
| Mi, K | 1 |
| Cheng, J | 1 |
| Gu, C | 1 |
| Huang, J | 2 |
| Sun, HB | 1 |
| Xing, WQ | 1 |
| Liu, XB | 1 |
| Zheng, Y | 1 |
| Yang, SJ | 1 |
| Wang, ZF | 1 |
| Liu, SL | 1 |
| Ba, YF | 1 |
| Zhang, RX | 1 |
| Liu, BX | 1 |
| Fan, CC | 1 |
| Chen, PN | 1 |
| Liang, GH | 1 |
| Yu, YK | 1 |
| Wang, HR | 1 |
| Li, HM | 1 |
| Li, ZX | 1 |
| Lalani, SS | 1 |
| Anasir, MI | 1 |
| Poh, CL | 1 |
| Khan, IT | 1 |
| Nadeem, M | 1 |
| Imran, M | 1 |
| Khalique, A | 1 |
| Raspini, B | 1 |
| Porri, D | 1 |
| De Giuseppe, R | 1 |
| Chieppa, M | 1 |
| Liso, M | 1 |
| Cerbo, RM | 1 |
| Civardi, E | 1 |
| Garofoli, F | 1 |
| Monti, MC | 1 |
| Vacca, M | 1 |
| De Angelis, M | 1 |
| Cena, H | 1 |
| Kong, D | 1 |
| Han, X | 1 |
| Zhou, Y | 5 |
| Xue, H | 1 |
| Zhang, W | 1 |
| Ruan, Z | 1 |
| Li, S | 2 |
| Noer, PR | 1 |
| Kjaer-Sorensen, K | 1 |
| Juhl, AK | 1 |
| Goldstein, A | 1 |
| Ke, C | 1 |
| Oxvig, C | 1 |
| Duan, C | 1 |
| Kong, F | 2 |
| Lin, S | 1 |
| Wang, Z | 5 |
| Bhattacharya, R | 1 |
| Mazumder, D | 1 |
| Yan, X | 1 |
| Ma, C | 1 |
| Tang, Y | 1 |
| Kong, X | 1 |
| Lu, J | 2 |
| Zhang, M | 3 |
| Vital-Jacome, M | 1 |
| Cazares-Granillo, M | 1 |
| Carrillo-Reyes, J | 1 |
| Buitron, G | 1 |
| Jacob, SI | 1 |
| Douair, I | 1 |
| Maron, L | 1 |
| Ménard, G | 1 |
| Rusjan, P | 1 |
| Sabioni, P | 1 |
| Di Ciano, P | 1 |
| Mansouri, E | 1 |
| Boileau, I | 1 |
| Laveillé, A | 1 |
| Capet, M | 1 |
| Duvauchelle, T | 1 |
| Schwartz, JC | 1 |
| Robert, P | 1 |
| Le Foll, B | 1 |
| Xia, Y | 2 |
| Chen, S | 2 |
| Luo, M | 1 |
| Wu, J | 4 |
| Cai, S | 1 |
| He, Y | 2 |
| Garbacz, P | 1 |
| Misiak, M | 1 |
| Jackowski, K | 1 |
| Yuan, Q | 1 |
| Sherrell, PC | 1 |
| Chen, J | 2 |
| Bi, X | 1 |
| Nutho, B | 1 |
| Mahalapbutr, P | 1 |
| Hengphasatporn, K | 1 |
| Pattaranggoon, NC | 1 |
| Simanon, N | 1 |
| Shigeta, Y | 1 |
| Hannongbua, S | 1 |
| Rungrotmongkol, T | 1 |
| Caffrey, PJ | 1 |
| Kher, R | 1 |
| Bian, K | 1 |
| Delaney, S | 1 |
| Xue, J | 1 |
| Wu, P | 1 |
| Xu, L | 1 |
| Yuan, Y | 1 |
| Luo, J | 1 |
| Ye, S | 1 |
| Ustriyana, P | 1 |
| Wei, B | 1 |
| Raee, E | 1 |
| Hu, Y | 1 |
| Wesdemiotis, C | 1 |
| Sahai, N | 1 |
| Kaur, A | 1 |
| Nigam, K | 1 |
| Srivastava, S | 2 |
| Tyagi, A | 1 |
| Dang, S | 1 |
| Millar, JE | 1 |
| Bartnikowski, N | 1 |
| Passmore, MR | 1 |
| Obonyo, NG | 1 |
| Malfertheiner, MV | 1 |
| von Bahr, V | 1 |
| Redd, MA | 1 |
| See Hoe, L | 1 |
| Ki, KK | 1 |
| Pedersen, S | 1 |
| Boyle, AJ | 1 |
| Baillie, JK | 1 |
| Shekar, K | 1 |
| Palpant, N | 1 |
| Suen, JY | 1 |
| Matthay, MA | 1 |
| McAuley, DF | 1 |
| Fraser, JF | 1 |
| Settles, JA | 1 |
| Gerety, GF | 1 |
| Spaepen, E | 1 |
| Suico, JG | 1 |
| Child, CJ | 1 |
| Oh, BL | 1 |
| Lee, JS | 1 |
| Lee, EY | 1 |
| Lee, HY | 1 |
| Yu, HG | 1 |
| Leslie, I | 1 |
| Boos, LA | 1 |
| Larkin, J | 1 |
| Pickering, L | 1 |
| Lima, HK | 1 |
| Vogel, K | 1 |
| Hampel, D | 1 |
| Wagner-Gillespie, M | 1 |
| Fogleman, AD | 1 |
| Ferraz, SL | 1 |
| O'Connor, M | 1 |
| Mazzucchelli, TG | 1 |
| Kajiyama, H | 1 |
| Suzuki, S | 1 |
| Shimbo, A | 1 |
| Utsumi, F | 1 |
| Yoshikawa, N | 1 |
| Kikkawa, F | 1 |
| Javvaji, PK | 1 |
| Dhali, A | 1 |
| Francis, JR | 1 |
| Kolte, AP | 1 |
| Roy, SC | 1 |
| Selvaraju, S | 1 |
| Mech, A | 1 |
| Sejian, V | 1 |
| DeSilva, S | 1 |
| Vaidya, SS | 1 |
| Mao, C | 1 |
| Akhatayeva, Z | 1 |
| Cheng, H | 1 |
| Zhang, G | 1 |
| Jiang, F | 1 |
| Meng, X | 1 |
| Elnour, IE | 1 |
| Lan, X | 1 |
| Song, E | 1 |
| Rohde, S | 1 |
| Antonides, CFJ | 1 |
| Muslem, R | 1 |
| de Woestijne, PCV | 1 |
| der Meulen, MHV | 1 |
| Kraemer, US | 1 |
| Dalinghaus, M | 1 |
| Bogers, AJJC | 1 |
| Pourmand, A | 1 |
| Ghassemi, M | 1 |
| Sumon, K | 1 |
| Amini, SB | 1 |
| Hood, C | 1 |
| Sikka, N | 1 |
| Duan, H | 1 |
| Chen, WP | 1 |
| Fan, M | 1 |
| Wang, WP | 1 |
| Yu, L | 1 |
| Tan, SJ | 1 |
| Xin, S | 1 |
| Wan, LJ | 1 |
| Guo, YG | 1 |
| Tanda, S | 1 |
| Gingl, K | 1 |
| Ličbinský, R | 1 |
| Hegrová, J | 1 |
| Goessler, W | 1 |
| Li, ZL | 1 |
| Zhou, YL | 1 |
| Yan, W | 1 |
| Luo, L | 1 |
| Su, ZZ | 1 |
| Fan, MZ | 1 |
| Wang, SR | 1 |
| Zhao, WG | 1 |
| Xu, D | 1 |
| Hassan, HM | 1 |
| Jiang, Z | 1 |
| Bachmann, KF | 1 |
| Haenggi, M | 1 |
| Jakob, SM | 1 |
| Takala, J | 1 |
| Gattinoni, L | 1 |
| Berger, D | 1 |
| Bentley, RF | 1 |
| Vecchiarelli, E | 1 |
| Banks, L | 1 |
| Gonçalves, PEO | 1 |
| Thomas, SG | 1 |
| Goodman, JM | 1 |
| Mather, K | 1 |
| Boachie, R | 1 |
| Anini, Y | 1 |
| Panahi, S | 1 |
| Anderson, GH | 1 |
| Luhovyy, BL | 1 |
| Nafie, MS | 1 |
| Arafa, K | 1 |
| Sedky, NK | 1 |
| Alakhdar, AA | 1 |
| Arafa, RK | 1 |
| Fan, S | 1 |
| Hu, H | 1 |
| Liang, J | 1 |
| Hu, BC | 1 |
| Wen, Z | 1 |
| Hu, D | 1 |
| Liu, YY | 1 |
| Chu, Q | 1 |
| Wu, MC | 1 |
| Lu, X | 1 |
| Wang, D | 1 |
| Hu, M | 1 |
| Shen, H | 1 |
| Yao, M | 1 |
| Dahlgren, RA | 1 |
| Vysloužil, J | 1 |
| Kulich, P | 1 |
| Zeman, T | 1 |
| Vaculovič, T | 1 |
| Tvrdoňová, M | 1 |
| Mikuška, P | 1 |
| Večeřa, Z | 1 |
| Stráská, J | 1 |
| Moravec, P | 1 |
| Balcar, VJ | 1 |
| Šerý, O | 1 |
| Qiao, L | 1 |
| Xiong, X | 1 |
| Peng, X | 1 |
| Zheng, J | 1 |
| Duan, J | 1 |
| Xiao, W | 1 |
| Zhou, HY | 1 |
| Sui, ZY | 1 |
| Zhao, FL | 1 |
| Sun, YN | 1 |
| Wang, HY | 1 |
| Han, BH | 1 |
| Jintao, X | 1 |
| Shasha, Y | 1 |
| Jincai, W | 1 |
| Chunyan, L | 1 |
| Mengya, Y | 1 |
| Yongli, S | 1 |
| Rasoanirina, BNV | 1 |
| Lassoued, MA | 1 |
| Miladi, K | 1 |
| Razafindrakoto, Z | 1 |
| Chaâbane-Banaoues, R | 1 |
| Ramanitrahasimbola, D | 1 |
| Cornet, M | 1 |
| Sfar, S | 1 |
| Liang, C | 1 |
| Xing, Q | 1 |
| Yi, JL | 1 |
| Zhang, YQ | 1 |
| Li, CY | 1 |
| Tang, SJ | 1 |
| Gao, C | 1 |
| Sun, X | 3 |
| Peng, M | 1 |
| Sun, XF | 1 |
| Zhang, T | 1 |
| Shi, JH | 1 |
| Liao, CX | 1 |
| Gao, WJ | 1 |
| Sun, LL | 1 |
| Gao, Y | 1 |
| Cao, WH | 1 |
| Lyu, J | 1 |
| Yu, CQ | 1 |
| Wang, SF | 1 |
| Pang, ZC | 1 |
| Cong, LM | 1 |
| Dong, Z | 1 |
| Wu, F | 1 |
| Wu, XP | 1 |
| Jiang, GH | 1 |
| Wang, XJ | 1 |
| Wang, BY | 1 |
| Li, LM | 1 |
| Pan, L | 1 |
| Wan, SP | 1 |
| Yi, HWL | 1 |
| He, HJ | 1 |
| Yong, ZP | 1 |
| Shan, GL | 1 |
| Weng, TT | 1 |
| Yan, SQ | 1 |
| Gao, GP | 1 |
| Wei, C | 1 |
| Tao, FB | 1 |
| Shao, ZH | 1 |
| Yao, T | 1 |
| Dong, S | 1 |
| Shi, S | 1 |
| Feng, YL | 1 |
| Zhang, YW | 1 |
| Wang, SP | 1 |
| Shi, AX | 1 |
| Operario, D | 1 |
| Zhang, ZH | 1 |
| Zhu, XF | 1 |
| Zaller, N | 1 |
| Gao, P | 1 |
| Sun, YH | 1 |
| Zhang, HB | 1 |
| Schiffman, HJ | 1 |
| Olufs, ZPG | 2 |
| Lasarev, MR | 1 |
| Wassarman, DA | 2 |
| Perouansky, M | 2 |
| Fan, X | 1 |
| Li, F | 1 |
| Qiu, J | 1 |
| Que, YY | 1 |
| Zhu, T | 1 |
| Zhang, FX | 2 |
| Ganetzky, B | 1 |
| Sun, YM | 1 |
| Chen, C | 1 |
| Wan, J | 1 |
| Ma, LH | 1 |
| Sun, YY | 1 |
| Miao, HH | 1 |
| Wu, YQ | 1 |
| Hamden, JE | 1 |
| Salehzadeh, M | 1 |
| Gray, KM | 1 |
| Forys, BJ | 1 |
| Soma, KK | 1 |
| Cao, Y | 5 |
| Ni, C | 5 |
| Yang, N | 3 |
| Shi, C | 2 |
| Zhong, Y | 2 |
| Cui, D | 2 |
| Guo, X | 7 |
| Zuo, CL | 1 |
| Wang, CM | 1 |
| Shen, T | 1 |
| Zhou, JP | 1 |
| Hao, XR | 1 |
| Pan, YZ | 1 |
| Liu, HC | 1 |
| Lian, QQ | 1 |
| Lin, H | 1 |
| Qian, Y | 1 |
| Shao, X | 1 |
| Ma, Z | 1 |
| Xia, T | 1 |
| Gu, X | 1 |
| Meng, S | 1 |
| Cao, L | 2 |
| Chen, Y | 1 |
| Zuo, Z | 2 |
| Peng, S | 1 |
| Roug, A | 1 |
| Talley, H | 1 |
| Davis, T | 1 |
| Roueche, M | 1 |
| DeBloois, D | 1 |
| Yin, L | 1 |
| Bao, F | 1 |
| Li, K | 3 |
| Ran, M | 1 |
| Yang, H | 1 |
| Dong, H | 1 |
| Friese, MB | 1 |
| Nathan, M | 1 |
| Culley, DJ | 4 |
| Crosby, G | 4 |
| He, J | 1 |
| Tian, X | 1 |
| Manyande, A | 1 |
| Xiang, H | 1 |
| Zhang, JC | 1 |
| Zhang, WJ | 1 |
| Zhao, Q | 1 |
| Chen, BN | 1 |
| Luo, YP | 1 |
| Cheng, Y | 1 |
| Lu, H | 1 |
| Erasso, DM | 2 |
| Camporesi, EM | 2 |
| Mangar, D | 1 |
| Saporta, S | 2 |
| Li, ZQ | 1 |
| Rong, XY | 1 |
| Liu, YJ | 1 |
| Tian, XS | 1 |
| Mo, N | 1 |
| Chui, DH | 1 |
| Guo, XY | 1 |
| Lu, B | 1 |
| Zheng, B | 1 |
| Qi, B | 1 |
| Deng, Y | 1 |
| Su, D | 1 |
| Ji, M | 3 |
| Dong, L | 1 |
| Jia, M | 2 |
| Ju, L | 1 |
| Xie, Z | 4 |
| Li, XM | 1 |
| Su, F | 1 |
| Ji, MH | 1 |
| Zhang, GF | 1 |
| Qiu, LL | 1 |
| Gao, J | 1 |
| Yang, JJ | 1 |
| Morgan, EE | 1 |
| Casabianca, AB | 1 |
| Khouri, SJ | 1 |
| Kalinoski, AL | 1 |
| Callaway, JK | 1 |
| Jones, NC | 1 |
| Royse, AG | 1 |
| Royse, CF | 1 |
| Qian, M | 1 |
| Acharya, NK | 1 |
| Goldwaser, EL | 1 |
| Forsberg, MM | 1 |
| Godsey, GA | 1 |
| Johnson, CA | 1 |
| Sarkar, A | 1 |
| DeMarshall, C | 1 |
| Kosciuk, MC | 1 |
| Dash, JM | 1 |
| Hale, CP | 1 |
| Leonard, DM | 1 |
| Appelt, DM | 1 |
| Nagele, RG | 1 |
| Ge, HW | 1 |
| Hu, WW | 1 |
| Ma, LL | 1 |
| Kong, FJ | 1 |
| Chemali, JJ | 1 |
| Kenny, JD | 1 |
| Olutola, O | 1 |
| Taylor, NE | 1 |
| Kimchi, EY | 1 |
| Purdon, PL | 1 |
| Brown, EN | 1 |
| Solt, K | 1 |
| Hao, S | 2 |
| Wang, HL | 1 |
| Xue, ZG | 1 |
| Liao, QW | 1 |
| Fang, H | 1 |
| Hou, D | 1 |
| Hou, J | 1 |
| Walters, JL | 1 |
| Chelonis, JJ | 1 |
| Fogle, CM | 1 |
| Orser, BA | 1 |
| Paule, MG | 1 |
| Gao, Q | 1 |
| Rebecchi, MJ | 3 |
| Liu, L | 3 |
| Jungbauer, S | 1 |
| Buehler, PK | 1 |
| Neubauer, J | 1 |
| Haas, C | 1 |
| Heitzmann, D | 1 |
| Tegtmeier, I | 1 |
| Sterner, C | 1 |
| Barhanin, J | 1 |
| Georgieff, M | 1 |
| Warth, R | 1 |
| Thomas, J | 1 |
| Bi, J | 1 |
| Lei, W | 1 |
| Xia, C | 1 |
| Jaw, J | 1 |
| Xu, M | 1 |
| Bailey, PA | 1 |
| Hague, BA | 1 |
| Davis, M | 1 |
| Major, MD | 1 |
| Zubrod, CJ | 1 |
| Brakenhoff, JE | 1 |
| Yi, D | 1 |
| Chui, D | 1 |
| Nguyen, LT | 1 |
| Moore, LC | 1 |
| Glass, PS | 2 |
| Brink, PR | 2 |
| Bains, R | 1 |
| Moe, MC | 1 |
| Vinje, ML | 1 |
| Berg-Johnsen, J | 1 |
| Isaeva, EV | 1 |
| Matsuura, T | 2 |
| Oda, Y | 2 |
| Tanaka, K | 2 |
| Mori, T | 1 |
| Nishikawa, K | 2 |
| Asada, A | 2 |
| Duan, K | 1 |
| Ouyang, W | 1 |
| Chen, M | 1 |
| Wang, S | 1 |
| Eckel, B | 1 |
| Richtsfeld, M | 1 |
| Starker, L | 1 |
| Blobner, M | 1 |
| Whittington, RA | 1 |
| Virág, L | 1 |
| Stratmann, G | 1 |
| Sall, JW | 1 |
| Bell, JS | 1 |
| Alvi, RS | 1 |
| May, Ld | 1 |
| Ku, B | 1 |
| Dowlatshahi, M | 1 |
| Dai, R | 1 |
| Bickler, PE | 2 |
| Russell, I | 1 |
| Lee, MT | 1 |
| Hrubos, MW | 1 |
| Chiu, C | 1 |
| Tan, M | 1 |
| Huang, WC | 1 |
| Hsieh, YS | 1 |
| Chen, IH | 1 |
| Wang, CH | 1 |
| Chang, HW | 1 |
| Yang, CC | 1 |
| Ku, TH | 1 |
| Yeh, SR | 1 |
| Chuang, YJ | 1 |
| Kawano, T | 1 |
| Chi, H | 1 |
| Kimura, M | 1 |
| Kawano, H | 1 |
| Eguchi, S | 1 |
| Oshita, S | 1 |
| Kin, N | 1 |
| Weismann, C | 1 |
| Chakravarti, S | 1 |
| Bodian, C | 1 |
| Hossain, S | 1 |
| Krol, M | 1 |
| Hollinger, I | 1 |
| Nguyen, K | 1 |
| Mittnacht, AJ | 1 |
| Leoni, RF | 1 |
| Paiva, FF | 1 |
| Henning, EC | 1 |
| Nascimento, GC | 1 |
| Tannús, A | 1 |
| de Araujo, DB | 1 |
| Silva, AC | 1 |
| Mawhinney, LJ | 1 |
| de Rivero Vaccari, JP | 1 |
| Alonso, OF | 1 |
| Jimenez, CA | 1 |
| Furones, C | 1 |
| Moreno, WJ | 1 |
| Lewis, MC | 1 |
| Dietrich, WD | 1 |
| Bramlett, HM | 1 |
| Lin, D | 1 |
| Washington, JM | 1 |
| Ji, C | 2 |
| Feng, C | 2 |
| Xu, Z | 3 |
| Wu, A | 3 |
| Yue, Y | 3 |
| Chaparro, RE | 1 |
| Quiroga Del Rio, CE | 1 |
| Karlnoski, R | 1 |
| Jia, X | 2 |
| Schöffmann, G | 1 |
| Vettorato, E | 1 |
| Burke, JG | 1 |
| Gibson, AJ | 1 |
| Clutton, ER | 1 |
| Cone, FE | 1 |
| Steinhart, MR | 1 |
| Oglesby, EN | 1 |
| Kalesnykas, G | 1 |
| Pease, ME | 1 |
| Quigley, HA | 1 |
| Chang, DJ | 1 |
| Chang, CH | 1 |
| Hong, YW | 1 |
| Lee, WK | 1 |
| Shim, YH | 1 |
| Borghese, CM | 1 |
| Xiong, W | 1 |
| Oh, SI | 1 |
| Ho, A | 1 |
| Mihic, SJ | 1 |
| Lovinger, DM | 1 |
| Homanics, GE | 1 |
| Eger, EI | 8 |
| Harris, RA | 1 |
| Qu, X | 1 |
| Li, SY | 1 |
| Xia, LX | 1 |
| Zhao, YL | 1 |
| Yang, L | 1 |
| Chen, YL | 1 |
| Wang, JT | 1 |
| Luo, AL | 1 |
| Rozenberg, S | 2 |
| Besse, S | 2 |
| Vivien, B | 2 |
| Coriat, P | 1 |
| Riou, B | 2 |
| Nickalls, RW | 1 |
| Mapleson, WW | 1 |
| Baxter, MG | 2 |
| Yukhananov, R | 3 |
| Butterfield, NN | 1 |
| Graf, P | 1 |
| Ries, CR | 1 |
| MacLeod, BA | 1 |
| Crosby, CA | 1 |
| Weber, F | 1 |
| Gruber, M | 1 |
| Taeger, K | 1 |
| Sanders, RD | 1 |
| Patel, N | 1 |
| Hossain, M | 1 |
| Ma, D | 1 |
| Maze, M | 1 |
| Xia, Z | 1 |
| Luo, T | 1 |
| Loguinov, A | 1 |
| Zhan, X | 1 |
| Fahlman, CS | 1 |
| Arai, S | 1 |
| Yoshioka, K | 1 |
| Suzuki, C | 1 |
| Takahashi, H | 1 |
| Itoh, T | 1 |
| Nakano, S | 1 |
| Amour, J | 1 |
| Tavernier, B | 1 |
| Hartley, CJ | 1 |
| Reddy, AK | 1 |
| Madala, S | 1 |
| Michael, LH | 1 |
| Entman, ML | 1 |
| Taffet, GE | 1 |
| El Beheiry, H | 1 |
| Ouanounou, A | 3 |
| Carlen, PL | 3 |
| Norberg, A | 1 |
| Hahn, RG | 1 |
| Olsson, J | 1 |
| Prough, DS | 1 |
| Børsheim, E | 1 |
| Wolf, S | 1 |
| Minton, RK | 1 |
| Svensén, CH | 1 |
| Ikeshita, K | 1 |
| Ito, K | 1 |
| Vutskits, L | 1 |
| Lysakowski, C | 1 |
| Czarnetzki, C | 1 |
| Jenny, B | 1 |
| Copin, JC | 1 |
| Tramèr, MR | 1 |
| Lerman, J | 2 |
| Gregory, GA | 2 |
| Willis, MM | 2 |
| Conzen, P | 1 |
| Peter, K | 1 |
| Kurth, CD | 1 |
| Steven, JM | 1 |
| Nicolson, SC | 1 |
| Caldwell, JE | 1 |
| Palmisano, BW | 1 |
| Mehner, RW | 1 |
| Stowe, DF | 1 |
| Bosnjak, ZJ | 1 |
| Kampine, JP | 1 |
| Gold, MI | 1 |
| Abello, D | 1 |
| Herrington, C | 1 |
| Katoh, T | 2 |
| Suguro, Y | 2 |
| Ikeda, T | 1 |
| Kazama, T | 2 |
| Ikeda, K | 2 |
| Belant, JL | 1 |
| el-Beheiry, H | 2 |
| Thiel, A | 1 |
| Schindler, E | 1 |
| Dyckmans, D | 1 |
| Hempelmann, G | 1 |
| Markakis, DA | 1 |
| Lau, M | 1 |
| Brown, R | 1 |
| Luks, AM | 1 |
| Sharma, ML | 1 |
| Fisher, DM | 1 |
| Kudoh, A | 1 |
| Sakai, T | 1 |
| Ishihara, H | 1 |
| Matsuki, A | 1 |
| Muir, WW | 1 |
| Ford, JL | 1 |
| Karpa, GE | 1 |
| Harrison, EE | 1 |
| Gadawski, JE | 1 |
| Kitamura, A | 1 |
| Hoshino, T | 1 |
| Kon, T | 1 |
| Ogawa, R | 1 |
| Magnusson, KR | 1 |
| Scanga, C | 1 |
| Wagner, AE | 1 |
| Dunlop, C | 1 |
| Hartman, PS | 1 |
| Ishii, N | 1 |
| Kayser, EB | 1 |
| Morgan, PG | 1 |
| Sedensky, MM | 1 |
| Mathew, JP | 1 |
| Weatherwax, KJ | 1 |
| East, CJ | 1 |
| White, WD | 1 |
| Reves, JG | 1 |
| Simon, W | 1 |
| Hapfelmeier, G | 1 |
| Kochs, E | 1 |
| Zieglgänsberger, W | 1 |
| Rammes, G | 1 |
| Drake, WT | 1 |
| Creighan, M | 1 |
| Sims, DE | 1 |
| Nakajima, R | 1 |
| Takenoshita, M | 1 |
| Steinbach, JH | 1 |
| Murray, DJ | 1 |
| Mehta, MP | 1 |
| Forbes, RB | 1 |
| Strum, DP | 1 |
| Unadkat, JD | 1 |
| Johnson, BH | 1 |
| Carpenter, RL | 1 |
| Rampil, IJ | 2 |
| Lockhart, SH | 1 |
| Zwass, MS | 1 |
| Peterson, N | 1 |
| Yasuda, N | 2 |
| Weiskopf, RB | 1 |
| Damask, MC | 1 |
| Dwyer, RC | 1 |
| Fee, JP | 1 |
| Howard, PJ | 1 |
| Clarke, RS | 1 |
| Murat, I | 1 |
| Hoerter, J | 1 |
| Ventura-Clapier, R | 1 |
| Dresner, DL | 1 |
| Basta, SJ | 1 |
| Ali, HH | 1 |
| Schwartz, AF | 1 |
| Embree, PB | 1 |
| Wargin, WA | 1 |
| Lai, AA | 1 |
| Brady, KA | 1 |
| Savarese, JJ | 1 |
| Lampe, GH | 2 |
| Wauk, LZ | 2 |
| Whitendale, P | 2 |
| Way, WL | 1 |
| Kozmary, SV | 1 |
| Donegan, JH | 2 |
| Rupp, SM | 1 |
| Fouts, KE | 1 |
| Rose, BM | 1 |
| Litt, LL | 1 |
| Wilson, CB | 1 |
| Badgwell, JM | 1 |
| Heavner, JE | 1 |
| Kytta, J | 1 |
| Jorch, G | 1 |
| Woike, H | 1 |
| Rabe, H | 1 |
| Reinhold, P | 1 |
| Targ, AG | 1 |
| Bazin, JE | 1 |
| Dalens, B | 1 |
| Veyret, E | 1 |
| Picard, P | 1 |
| Haberer, JP | 1 |
| Schwartz, AE | 1 |
| Tuttle, RH | 1 |
| Poppers, PJ | 1 |
| Cook, DR | 1 |
| Calderini, E | 1 |
| Salvo, I | 1 |
| Colombo, S | 1 |
| Zoia, E | 1 |
| Ferrario, P | 1 |
| Giannini, A | 1 |
| Torri, G | 1 |
| Gross, JB | 1 |
| Alexander, CM | 1 |
| Schmitt-Bantel, BI | 1 |
| Ohqvist, G | 1 |
| Settergren, G | 1 |
| Ekeström, S | 1 |
| Brodin, LA | 1 |
| Eger, RR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Gut Microbiome and Blood Indices in Patients With AD and Their Spousal Caregivers[NCT05601856] | 104 participants (Anticipated) | Observational | 2022-12-15 | Recruiting | |||
| The Effect of Chronic Opioid Use on Minimum Alveolar Concentration of Sevoflurane for Maintaining Bispectral(BIS) Index Below 50 ; Prospective, Blind Study[NCT02582437] | 20 participants (Anticipated) | Interventional | 2015-06-30 | Recruiting | |||
| Effect of Two Plasma Concentrations of Remifentanil Through Target Controlled Anesthesia on Frequency and Intensity of Coughing During Extubation: Randomized Controlled Clinical Trial[NCT02711904] | Phase 4 | 110 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| Evaluation of a Peri-Operative Continuous Bilateral Erector Spinae Plane (ESP) Continuous Catheter After Open Cardiac Surgery in Adults[NCT03901612] | Phase 4 | 0 participants (Actual) | Interventional | 2019-01-05 | Withdrawn (stopped due to covid and surgeon left) | ||
| Bilateral Erector Spinae Plane (ESP) Catheters Versus Single Shot ESP Block for Open Heart Surgery in Infants[NCT03593642] | 40 participants (Actual) | Interventional | 2018-10-01 | Completed | |||
| Impact of Dexmedetomidine on the Incidence of Postoperative Delirium in Patients After Cardiac Surgery: a Randomized, Double-blinded, and Placebo-controlled Clinical Trial[NCT02267538] | Phase 4 | 285 participants (Actual) | Interventional | 2014-11-30 | Completed | ||
| Association Between Changes in Cerebral Gray Matter Volume and Postoperative Cognitive Dysfunction in Elderly Patients Following Sevoflurane Anesthesia (POCD-MRI)[NCT02045004] | 100 participants (Actual) | Observational | 2015-07-14 | Completed | |||
| Near Infrared Spectroscopy Monitoring of Cerebral Oxygen Saturation in Neonatal Cardiac Surgery - Comparison With Common Methods of Estimating Adequate Systemic Perfusion[NCT00166101] | 25 participants (Actual) | Observational | 2002-08-31 | Completed | |||
| Optimal Positive End-expiratory Pressure (PEEP) in Prone Position During Spine Surgery. A Prospective Observational Study[NCT04024410] | 20 participants (Actual) | Observational | 2019-06-03 | Completed | |||
| The Quality of Recovery After General Anesthesia With Desflurane and Sevoflurane in Endoscopic Ureteral Lithotripsy[NCT04712162] | 60 participants (Actual) | Interventional | 2019-11-19 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Delirium was assessed with the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) twice daily during the first five days after surgery. (NCT02267538)
Timeframe: During the first five days after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| DEX Group | 7 |
| CTRL Group | 11 |
Results was presented as median (95% confidence interval). (NCT02267538)
Timeframe: From end of surgery until discharge from hospital or 30 days after surgery
| Intervention | days (Median) |
|---|---|
| DEX Group | 9 |
| CTRL Group | 9 |
Results was presented as median (95% confidence interval). (NCT02267538)
Timeframe: From end of surgery until discharge from Intensive Care Unit or 30 days after surgery
| Intervention | hours (Median) |
|---|---|
| DEX Group | 45.0 |
| CTRL Group | 46.0 |
"Cognitive function was assessed with the Mini Mental State Examination (MMSE) at baseline (the day before surgery) and on the sixth day after surgery, and with modified telephone interview for cognitive status (m-TICS) on the 30th day after surgery.~The introduction of MMSE scale has been explained in the baseline part in the result section.~The Telephone Interview for Cognitive Status-modified scale(m-TICS) is one of the most popular telephone interview-based screening instruments for mild cognitive impairment and dementia. It consists 11 items including wordlist memory, orientation, attention, repetition, conceptual knowledge and nonverbal praxis, which score ranges from 0 to 48, with higher scores indicating better cognitive function" (NCT02267538)
Timeframe: on the sixth day after surgery, and on the 30th day after surgery
| Intervention | units on a scale (Median) | |
|---|---|---|
| MMSE score on postoperative day 6 | m-TICS score on postoperative day 30 | |
| CTRL Group | 29 | 34 |
| DEX Group | 29 | 34 |
Non-delirium complications was defined as any conditions other than delirium that occurred during the first 30 days after surgery and required therapeutic intervention.Complications listed here were not considered adverse events in this study. (NCT02267538)
Timeframe: Occurrence of non-delirium complications will be monitored until 30 days after surgery.
| Intervention | Participants (Count of Participants) | |||||||
|---|---|---|---|---|---|---|---|---|
| Stroke | New onset arrythmia | Pulmonary complications | Upper gastrointestinal bleeding | Surgical bleeding | Wound dehiscence or infection | Acute kidney injury | IABP assistance | |
| CTRL Group | 3 | 51 | 27 | 4 | 3 | 7 | 44 | 12 |
| DEX Group | 3 | 42 | 15 | 2 | 3 | 11 | 37 | 6 |
Pain intensity was assessed daily at 8 am during the first five days after surgery with the Numeric Rating Scale (NRS, 0 = no pain, 10 = the worst possible pain). (NCT02267538)
Timeframe: During the first five days after surgery
| Intervention | units on a scale (Median) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Pain score after surgery(d1), at rest | Pain score after surgery(d2), at rest | Pain score after surgery(d3), at rest | Pain score after surgery(d4), at rest | Pain score after surgery(d5), at rest | Pain score after surgery(d1), with coughing | Pain score after surgery(d2), with coughing | Pain score after surgery(d3), with coughing | Pain score after surgery(d4), with coughing | Pain score after surgery(d5), with coughing | |
| CTRL Group | 3 | 3 | 2 | 2 | 1 | 4 | 4 | 4 | 3 | 2 |
| DEX Group | 3 | 4 | 3 | 2 | 2 | 4 | 5 | 4 | 3 | 2 |
Subjective sleep quality was assessed daily at 8 am during the first five days after surgery with the Numeric Rating Scale (NRS, 0 = best sleep, 10 = the worst possible sleep). (NCT02267538)
Timeframe: During the first five days after surgery
| Intervention | units on a scale (Median) | ||||
|---|---|---|---|---|---|
| Subjective sleep quality after surgery(d1), score | Subjective sleep quality after surgery(d2), score | Subjective sleep quality after surgery(d3), score | Subjective sleep quality after surgery(d4), score | Subjective sleep quality after surgery(d5), score | |
| CTRL Group | 2 | 3 | 2 | 2 | 2 |
| DEX Group | 2 | 3 | 2 | 2 | 2 |
4 reviews available for isoflurane and Aging
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Inhalation anaesthesia at the extremes of age: geriatric anaesthesia.
Topics: Aged; Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Desflurane; Geriatrics; Humans; Isoflu | 1995 |
Desflurane clinical pharmacokinetics and pharmacodynamics.
Topics: Aging; Anesthetics; Animals; Cardiovascular System; Central Nervous System; Desflurane; Drug Interac | 1994 |
Newborn anaesthesia: pharmacological considerations.
Topics: Aging; Anesthesia; Anesthesia, Inhalation; Cardiovascular Diseases; Dose-Response Relationship, Drug | 1986 |
17 trials available for isoflurane and Aging
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Advance of age decreases the minimum alveolar concentrations of isoflurane and sevoflurane for maintaining bispectral index below 50.
Topics: Adult; Aged; Aging; Anesthetics, Inhalation; Double-Blind Method; Drug Administration Schedule; Elec | 2009 |
Advance of age decreases the minimum alveolar concentrations of isoflurane and sevoflurane for maintaining bispectral index below 50.
Topics: Adult; Aged; Aging; Anesthetics, Inhalation; Double-Blind Method; Drug Administration Schedule; Elec | 2009 |
Advance of age decreases the minimum alveolar concentrations of isoflurane and sevoflurane for maintaining bispectral index below 50.
Topics: Adult; Aged; Aging; Anesthetics, Inhalation; Double-Blind Method; Drug Administration Schedule; Elec | 2009 |
Advance of age decreases the minimum alveolar concentrations of isoflurane and sevoflurane for maintaining bispectral index below 50.
Topics: Adult; Aged; Aging; Anesthetics, Inhalation; Double-Blind Method; Drug Administration Schedule; Elec | 2009 |
Factors affecting the decision to defer endotracheal extubation after surgery for congenital heart disease: a prospective observational study.
Topics: Adolescent; Aging; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Dissociative; Anesthetic | 2011 |
Factors affecting the decision to defer endotracheal extubation after surgery for congenital heart disease: a prospective observational study.
Topics: Adolescent; Aging; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Dissociative; Anesthetic | 2011 |
Factors affecting the decision to defer endotracheal extubation after surgery for congenital heart disease: a prospective observational study.
Topics: Adolescent; Aging; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Dissociative; Anesthetic | 2011 |
Factors affecting the decision to defer endotracheal extubation after surgery for congenital heart disease: a prospective observational study.
Topics: Adolescent; Aging; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Dissociative; Anesthetic | 2011 |
The effects of age, isoflurane and sevoflurane on atracurium in lambs.
Topics: Aging; Anesthetics, Inhalation; Animals; Atracurium; Body Temperature; Dose-Response Relationship, D | 2012 |
The correlation of the Narcotrend Index and classical electroencephalographic parameters with endtidal desflurane concentrations and hemodynamic parameters in different age groups.
Topics: Adolescent; Adult; Aging; Algorithms; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, | 2005 |
Development of a neurosurgical operating table for adult cattle and changes in intracranial pressure and blood pressure in adult cattle undergoing long-time isoflurane anesthesia.
Topics: Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Blood Glucose; | 2006 |
Differential electroencephalographic response to tracheal intubation between young and elderly during isoflurane and sevoflurane nitrous oxide anaesthesia.
Topics: Adult; Aged; Aged, 80 and over; Aging; Anesthetics, Combined; Anesthetics, Inhalation; Blood Pressur | 2007 |
Plasma concentrations of brain-derived neurotrophic factor in patients undergoing minor surgery: a randomized controlled trial.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Inhalation; Anestheti | 2008 |
[Transcranial doppler sonography. Effect of sevoflurane in comparison to isoflurane].
Topics: Adolescent; Adult; Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Body Height; Body Weight; | 1997 |
The pharmacokinetics and steady state pharmacodynamics of mivacurium in children.
Topics: Adolescent; Adult; Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Child, Preschool; | 1998 |
Effects of intramuscular administration of low doses of medetomidine and medetomidine-butorphanol in middle-aged and old dogs.
Topics: Adjuvants, Anesthesia; Aging; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Combined; A | 1999 |
Bispectral analysis during cardiopulmonary bypass: the effect of hypothermia on the hypnotic state.
Topics: Adjuvants, Anesthesia; Aged; Aging; Analgesics, Opioid; Anesthesia, General; Anesthetics, Inhalation | 2001 |
The additive contribution of nitrous oxide to isoflurane MAC in infants and children.
Topics: Aging; Anesthesia, Inhalation; Drug Synergism; Humans; Infant; Isoflurane; Nitrous Oxide; Pediatrics | 1991 |
Postoperative hypoxemia after nonabdominal surgery: a frequent event not caused by nitrous oxide.
Topics: Adult; Aged; Aging; Anesthesia, Inhalation; Female; Humans; Hypoxia; Intraoperative Period; Isoflura | 1990 |
Nitrous oxide and epinephrine-induced arrhythmias.
Topics: Adult; Aging; Anesthesia, Inhalation; Arrhythmias, Cardiac; Electrocardiography; Epinephrine; Female | 1990 |
Awakening concentrations of isoflurane are not affected by analgesic doses of morphine.
Topics: Adult; Aging; Anesthesia Recovery Period; Anesthesia, Inhalation; Clinical Trials as Topic; Double-B | 1988 |
The influence of isoflurane on blood flow in coronary bypass grafts.
Topics: Aging; Anesthesia, General; Blood Pressure; Body Weight; Cardiac Output; Coronary Artery Bypass; Cor | 1985 |
107 other studies available for isoflurane and Aging
| Article | Year |
|---|---|
Sevoflurane and isoflurane inhibit KCl-induced, Rho kinase-mediated, and PI3K-participated vasoconstriction in aged diabetic rat aortas.
Topics: Aging; Amides; Anesthetics, Inhalation; Animals; Aorta; Chromones; Diabetes Mellitus, Experimental; | 2021 |
A modified mouse model of perioperative neurocognitive disorders exacerbated by sleep fragmentation.
Topics: Aging; Animals; Disease Models, Animal; Isoflurane; Memory Disorders; Mice; Neurocognitive Disorders | 2023 |
Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer's mouse model are associated with hippocampal synaptic deficits in an age-dependent manner.
Topics: Aging; Alzheimer Disease; Amyloid; Animals; Animals, Newborn; Apoptosis; Biomarkers; Cognitive Dysfu | 2019 |
Ageing and genetic background influence anaesthetic effects in a D. melanogaster model of blunt trauma with brain injury
Topics: Aging; Anesthetics, Inhalation; Animals; Brain; Brain Injuries, Traumatic; Disease Models, Animal; D | 2020 |
Effects of PYRIN-containing Apaf1-like protein 1 on isoflurane-induced postoperative cognitive dysfunction in aged rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Disease Models, Animal; Gene Silencing; Hippocampus; Inflam | 2020 |
Neuroprotective effect of DUSP14 overexpression against isoflurane-induced inflammatory response, pyroptosis and cognitive impairment in aged rats through inhibiting the NLRP3 inflammasome.
Topics: Aging; Animals; Cognitive Dysfunction; Dual-Specificity Phosphatases; Inflammasomes; Inflammation; I | 2020 |
Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity.
Topics: Aging; Anesthetics, Inhalation; Animals; Animals, Genetically Modified; Drosophila; Electron Transpo | 2020 |
Sirtuin 3 protects against anesthesia/surgery-induced cognitive decline in aged mice by suppressing hippocampal neuroinflammation.
Topics: Aging; Anesthetics, Inhalation; Animals; Hippocampus; Inflammation Mediators; Isoflurane; Male; Mice | 2021 |
Isoflurane stress induces glucocorticoid production in mouse lymphoid organs.
Topics: Aging; Animals; Bone Marrow; Corticosterone; Female; Isoflurane; Lymphoid Tissue; Male; Mice, Inbred | 2021 |
Hypoxia-inducible factor-1α is involved in isoflurane-induced blood-brain barrier disruption in aged rats model of POCD.
Topics: Aging; Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Brain; Cells, Cultured; Hypoxia; Hypox | 2018 |
Isoflurane anesthesia in aged mice and effects of A1 adenosine receptors on cognitive impairment.
Topics: Aging; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Cognitive Dysfunction; Isoflurane; M | 2018 |
Circadian rhythm resynchronization improved isoflurane-induced cognitive dysfunction in aged mice.
Topics: Aging; Anesthetics, Inhalation; Animals; Body Temperature; Circadian Rhythm; CLOCK Proteins; Cogniti | 2018 |
Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment.
Topics: Aging; Amino Acid Chloromethyl Ketones; Anesthetics, Inhalation; Animals; Caspase 1; Cell Line, Tran | 2018 |
A Mixture of Butorphanol, Azaperone, and Medetomidine for the Immobilization of American Beavers ( Castor canadensis).
Topics: Aging; Analgesics, Opioid; Animals; Azaperone; Butorphanol; Drug Combinations; Female; Hypnotics and | 2018 |
NLRP3 inflammasome-dependent pyroptosis is proposed to be involved in the mechanism of age-dependent isoflurane-induced cognitive impairment.
Topics: Aging; Anesthetics, Inhalation; Cognition Disorders; Cytokines; Humans; Isoflurane; NLR Family, Pyri | 2018 |
Orexin-1 receptor is involved in ageing-related delayed emergence from general anaesthesia in rats.
Topics: Adenoviridae; Aging; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Inhalation; Anesth | 2018 |
Isoflurane anesthesia impairs the expression of immune neuromodulators in the hippocampus of aged mice.
Topics: Aged; Aging; Anesthetics, Inhalation; Animals; Chemokine CCL2; Cognitive Dysfunction; Gene Expressio | 2018 |
Isoflurane-Induced Postoperative Neurovascular and Cognitive Dysfunction Is Associated with VEGF Overexpression in Aged Rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Cognitive Dysfunction; Hippocampus; Is | 2019 |
Regional Metabolic Patterns of Abnormal Postoperative Behavioral Performance in Aged Mice Assessed by
Topics: Aging; Anesthesia; Animals; Anxiety; Aspartic Acid; Brain; Cerebral Cortex; Cognitive Dysfunction; F | 2020 |
Adiponectin improves isoflurane-induced cognitive dysfunction in elderly rats via inhibiting p38-MAPK signal pathway in hippocampus.
Topics: Adiponectin; Aging; Animals; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Isoflurane; | 2019 |
Minocycline attenuates cognitive impairment induced by isoflurane anesthesia in aged rats.
Topics: Aging; Anesthesia; Animals; Apoptosis; Arterial Pressure; CA1 Region, Hippocampal; Caspase 3; Cognit | 2013 |
Effects of isoflurane or propofol on postnatal hippocampal neurogenesis in young and aged rats.
Topics: Aging; Anesthesia, General; Anesthetics, Inhalation; Animals; Cell Differentiation; Cell Proliferati | 2013 |
Activation of the canonical nuclear factor-κB pathway is involved in isoflurane-induced hippocampal interleukin-1β elevation and the resultant cognitive deficits in aged rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Cognition; Hippocampus; Interleukin-1beta; Isoflurane; Male | 2013 |
Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice.
Topics: Aging; Alzheimer Disease; Analysis of Variance; Anesthetics, Inhalation; Animals; Desflurane; Diseas | 2014 |
Epigenetic enhancement of brain-derived neurotrophic factor signaling pathway improves cognitive impairments induced by isoflurane exposure in aged rats.
Topics: Aging; Animals; Association Learning; Brain-Derived Neurotrophic Factor; Cognition Disorders; Condit | 2014 |
Disruption of hippocampal neuregulin 1-ErbB4 signaling contributes to the hippocampus-dependent cognitive impairment induced by isoflurane in aged mice.
Topics: Aging; Anesthetics, Inhalation; Animals; Blotting, Western; Cognition Disorders; Down-Regulation; En | 2014 |
In vivo assessment of arterial stiffness in the isoflurane anesthetized spontaneously hypertensive rat.
Topics: Aging; Anesthetics, Inhalation; Animals; Echocardiography; Elasticity Imaging Techniques; Hypertensi | 2014 |
Memory impairment in rats after desflurane anesthesia is age and dose dependent.
Topics: Age Factors; Aging; Anesthetics, Inhalation; Animals; Desflurane; Dose-Response Relationship, Drug; | 2015 |
Isoflurane anesthesia results in reversible ultrastructure and occludin tight junction protein expression changes in hippocampal blood-brain barrier in aged rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Cognition; Hippocampus; Isoflurane; Ma | 2015 |
Isoflurane induced cognitive impairment in aged rats through hippocampal calcineurin/NFAT signaling.
Topics: Aging; Animals; Calcineurin; Cognition Disorders; Hippocampus; Isoflurane; Male; NFATC Transcription | 2015 |
Sevoflurane and Isoflurane induce structural changes in brain vascular endothelial cells and increase blood-brain barrier permeability: Possible link to postoperative delirium and cognitive decline.
Topics: Aging; Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Capillary Permeability; Cognition Diso | 2015 |
Endoplasmic reticulum stress pathway mediates isoflurane-induced neuroapoptosis and cognitive impairments in aged rats.
Topics: Activating Transcription Factors; Aging; Anesthetics, Inhalation; Animals; Apoptosis; Cognition Diso | 2015 |
Ageing delays emergence from general anaesthesia in rats by increasing anaesthetic sensitivity in the brain.
Topics: Aging; Anesthesia, General; Anesthetics; Animals; Brain; Electroencephalography; Isoflurane; Male; M | 2015 |
A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice.
Topics: Adenosine Triphosphate; Aging; Anesthetics, Inhalation; Animals; Antioxidants; Cognition Disorders; | 2015 |
BDNF pathway is involved in the protective effects of SS-31 on isoflurane-induced cognitive deficits in aging mice.
Topics: Aging; Anesthetics, Inhalation; Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; D | 2016 |
Minocycline attenuates post-operative cognitive impairment in aged mice by inhibiting microglia activation.
Topics: Aging; Animals; Anti-Inflammatory Agents; Appendectomy; Calcium-Binding Proteins; Cell Count; Cognit | 2016 |
Taurine Pretreatment Prevents Isoflurane-Induced Cognitive Impairment by Inhibiting ER Stress-Mediated Activation of Apoptosis Pathways in the Hippocampus in Aged Rats.
Topics: Aging; Animals; Apoptosis; Brain; Cognition Disorders; Endoplasmic Reticulum Stress; Hippocampus; Is | 2016 |
Single and repeated exposures to the volatile anesthetic isoflurane do not impair operant performance in aged rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Conditioning, Operant; Disease Models, Animal; Drug Adminis | 2016 |
Restoring Pharmacologic Preconditioning in the Aging Heart: Role of Mitophagy/Autophagy.
Topics: Aging; Anesthetics, Inhalation; Animals; Antioxidants; Autophagy; Cyclic N-Oxides; Heart; Isoflurane | 2017 |
Sex-dependent differences in the in vivo respiratory phenotype of the TASK-1 potassium channel knockout mouse.
Topics: Aging; Anesthetics, Inhalation; Animals; Animals, Newborn; Cohort Studies; Female; Humans; Hypercapn | 2017 |
Nobiletin ameliorates isoflurane-induced cognitive impairment via antioxidant, anti-inflammatory and anti-apoptotic effects in aging rats.
Topics: Aging; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Brain | 2016 |
Calcineurin/nuclear factor-κB signaling mediates isoflurane-induced hippocampal neuroinflammation and subsequent cognitive impairment in aged rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Calcineurin; Cognitive Dysfunction; Hippocampus; Humans; In | 2017 |
Incidence of post-anesthetic colic in non-fasted adult equine patients.
Topics: Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Butorphanol; Colic; Female; Food De | 2016 |
Anti-RAGE antibody attenuates isoflurane-induced cognitive dysfunction in aged rats.
Topics: Aging; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Blood-Br | 2017 |
Attenuation of isoflurane-induced preconditioning and reactive oxygen species production in the senescent rat heart.
Topics: Aging; Anesthetics, Inhalation; Animals; Cellular Senescence; Heart; Ischemic Preconditioning, Myoca | 2008 |
Isoflurane-induced depolarization of neural mitochondria increases with age.
Topics: Aging; Animals; Calcium; Cell Respiration; Cytosol; Female; Isoflurane; Membrane Potential, Mitochon | 2009 |
Effects of isoflurane on hippocampal seizures at immature rats in vivo.
Topics: Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Anticonvulsants; Disease Models, An | 2008 |
[Delayed effect of isoflurane on hippocampal proteome after anesthesia in adult and aged rats].
Topics: Age Factors; Aging; Anesthetics, Inhalation; Animals; Electrophoresis, Gel, Two-Dimensional; Female; | 2009 |
Transgenic Alzheimer mice have a larger minimum alveolar anesthetic concentration of isoflurane than their nontransgenic littermates.
Topics: Aging; Alzheimer Disease; Anesthetics, Inhalation; Animals; Isoflurane; Male; Mice; Mice, Transgenic | 2010 |
The differential effects of equipotent doses of isoflurane and desflurane on hippocampal acetylcholine levels in young and aged rats.
Topics: Acetylcholine; Aging; Anesthetics, Inhalation; Animals; Brain; Desflurane; Isoflurane; Rats; Rats, I | 2010 |
Isoflurane does not affect brain cell death, hippocampal neurogenesis, or long-term neurocognitive outcome in aged rats.
Topics: Aging; Algorithms; Anesthetics, Inhalation; Animals; Brain; Cell Death; Cell Differentiation; Cell P | 2010 |
Age-associated differences in activation of Akt/GSK-3beta signaling pathways and inhibition of mitochondrial permeability transition pore opening in the rat heart.
Topics: Aging; Anesthetics, Inhalation; Animals; Cardiotonic Agents; Glycogen Synthase Kinase 3; Glycogen Sy | 2010 |
Combined use of MS-222 (tricaine) and isoflurane extends anesthesia time and minimizes cardiac rhythm side effects in adult zebrafish.
Topics: Aging; Aminobenzoates; Anesthesia; Anesthetics; Anesthetics, Inhalation; Animals; Drug Synergism; He | 2010 |
Effects of aging on isoflurane-induced and protein kinase A-mediated activation of ATP-sensitive potassium channels in cultured rat aortic vascular smooth muscle cells.
Topics: Aging; Animals; Aorta; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Isoflurane; KATP Chann | 2010 |
Magnetic resonance imaging quantification of regional cerebral blood flow and cerebrovascular reactivity to carbon dioxide in normotensive and hypertensive rats.
Topics: Aging; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Carbon Dioxide; Cereb | 2011 |
Isoflurane/nitrous oxide anesthesia induces increases in NMDA receptor subunit NR2B protein expression in the aged rat brain.
Topics: Aging; Analysis of Variance; Anesthetics, Inhalation; Animals; Brain; Caspase 3; Cell Death; Dose-Re | 2012 |
Lidocaine attenuates cognitive impairment after isoflurane anesthesia in old rats.
Topics: Aging; Amyloid beta-Peptides; Anesthetics, Inhalation; Anesthetics, Local; Animals; Brain; Cognition | 2012 |
Isoflurane-induced spatial memory impairment by a mechanism independent of amyloid-beta levels and tau protein phosphorylation changes in aged rats.
Topics: Aging; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Hippocampus; Isoflurane; Male; Memor | 2012 |
Quantitative assessment of new cell proliferation in the dentate gyrus and learning after isoflurane or propofol anesthesia in young and aged rats.
Topics: Aging; Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Cell Proliferation; Dentate Gyrus; | 2012 |
Changes of learning and memory in aged rats after isoflurane inhalational anaesthesia correlated with hippocampal acetylcholine level.
Topics: Acetylcholine; Aging; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Brain; Brain Chemi | 2012 |
The effects of anesthesia, mouse strain and age on intraocular pressure and an improved murine model of experimental glaucoma.
Topics: Acepromazine; Aging; Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Axons; | 2012 |
Isoflurane-induced post-conditioning in senescent hearts is attenuated by failure to activate reperfusion injury salvage kinase pathway.
Topics: Aging; Animals; Cardiotonic Agents; Drug Evaluation, Preclinical; Glycogen Synthase Kinase 3; Glycog | 2012 |
Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice.
Topics: Aging; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Electrophysiological Phen | 2012 |
Hippocampal glutamate level and glutamate aspartate transporter (GLAST) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment.
Topics: Aging; Anesthetics, Inhalation; Animals; Blotting, Western; Excitatory Amino Acid Transporter 1; Exc | 2013 |
Minocycline mitigates isoflurane-induced cognitive impairment in aged rats.
Topics: Aging; Anesthetics, Inhalation; Animals; bcl-2-Associated X Protein; Caspase 3; Cells, Cultured; Cog | 2013 |
Myocardial effects of halothane and isoflurane in senescent rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Halothane; Isoflurane; Ma | 2002 |
Age-related iso-MAC charts for isoflurane, sevoflurane and desflurane in man.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Algorithms; Anesthetics, Inhalation; | 2003 |
Long-term impairment of acquisition of a spatial memory task following isoflurane-nitrous oxide anesthesia in rats.
Topics: Aging; Analysis of Variance; Anesthesia, General; Anesthetics, Inhalation; Animals; Isoflurane; Male | 2004 |
The effect of repeated isoflurane anesthesia on spatial and psychomotor performance in young and aged mice.
Topics: Aging; Anesthesia, General; Anesthetics, Inhalation; Animals; Female; Isoflurane; Maze Learning; Mic | 2004 |
Impaired acquisition of spatial memory 2 weeks after isoflurane and isoflurane-nitrous oxide anesthesia in aged rats.
Topics: Aging; Anesthetics, Combined; Anesthetics, Inhalation; Animals; Cognition; Isoflurane; Maze Learning | 2004 |
Isoflurane exerts antinociceptive and hypnotic properties at all ages in Fischer rats.
Topics: Aging; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Animals; Animals, Newborn; Dose-Response R | 2005 |
Effectiveness of isoflurane in inducing delayed preconditioning against myocardial infarction in vivo.
Topics: Aging; Anesthetics, Inhalation; Animals; Coronary Artery Bypass; Humans; Ischemic Preconditioning, M | 2006 |
General anesthesia does not reduce life expectancy in aged rats.
Topics: Aging; Anesthesia, General; Animals; Isoflurane; Life Expectancy; Longevity; Male; Nitrous Oxide; Ra | 2006 |
Isoflurane neuroprotection in rat hippocampal slices decreases with aging: changes in intracellular Ca2+ regulation and N-methyl-D-aspartate receptor-mediated Ca2+ influx.
Topics: Aging; Anesthetics, Inhalation; Animals; Animals, Newborn; Blotting, Western; Calcium; Calcium Signa | 2006 |
Effects of desflurane in senescent rat myocardium.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Anesthetics, Inhalation; Animals; | 2006 |
Effects of isoflurane on coronary blood flow velocity in young, old and ApoE(-/-) mice measured by Doppler ultrasound.
Topics: Aging; Animals; Apolipoproteins E; Blood Flow Velocity; Coronary Circulation; Coronary Vessels; Isof | 2007 |
L-type calcium channel blockade modifies anesthetic actions on aged hippocampal neurons.
Topics: Aging; Analysis of Variance; Anesthetics, Inhalation; Animals; Calcium; Calcium Channel Blockers; Ca | 2007 |
Population volume kinetics predicts retention of 0.9% saline infused in awake and isoflurane-anesthetized volunteers.
Topics: Adult; Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Pressure; Body Weight; Cardiac | 2007 |
Age and solubility of volatile anesthetics in blood.
Topics: Adult; Aged; Aging; Anesthetics; Blood Gas Analysis; Child; Child, Preschool; Cholesterol; Enflurane | 1984 |
Cerebral oxygenation during pediatric cardiac surgery using deep hypothermic circulatory arrest.
Topics: Aging; Anesthesia; Brain; Cardiac Surgical Procedures; Child, Preschool; Fentanyl; Hemodynamics; Hum | 1995 |
Direct myocardial effects of halothane and isoflurane. Comparison between adult and infant rabbits.
Topics: Aging; Animals; Animals, Newborn; Atrioventricular Node; Coronary Circulation; Halothane; Heart; Hea | 1994 |
Minimum alveolar concentration of desflurane in patients older than 65 yr.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anesthetics; Desflura | 1993 |
Influence of age on awakening concentrations of sevoflurane and isoflurane.
Topics: Adult; Aging; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics; Ethers; Female; Human | 1993 |
Isoflurane as an inhalation anesthetic for muskrats (Ondatra zibethicus).
Topics: Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Arousal; Arvicolinae; Behavior, Ani | 1995 |
Ageing potentiates anaesthetic-induced synaptic depression in hippocampal slices.
Topics: Aging; Anesthetics, Inhalation; Animals; Dendrites; Depression, Chemical; Evoked Potentials; Hippoca | 1996 |
Enhanced isoflurane suppression of excitatory synaptic transmission in the aged rat hippocampus.
Topics: Aging; Animals; Bicuculline; Calcium; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocam | 1998 |
Renin-aldosterone in elderly patients with hyperkalaemia under anaesthesia.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Anesthesia, General; Anesthetics, Inhalation; An | 1999 |
Patients with diabetic neuropathy are at risk of a greater intraoperative reduction in core temperature.
Topics: Abdomen; Aged; Aging; Anesthetics, Inhalation; Case-Control Studies; Diabetic Neuropathies; Female; | 2000 |
Changes in anesthetic sensitivity and glutamate receptors in the aging canine brain.
Topics: Aging; Analysis of Variance; Anesthetics, Inhalation; Animals; Brain; Cerebral Cortex; Dizocilpine M | 2000 |
Mitochondrial mutations differentially affect aging, mutability and anesthetic sensitivity in Caenorhabditis elegans.
Topics: Aging; Anesthetics, Inhalation; Animals; Caenorhabditis elegans; Electron Transport Complex I; Elect | 2001 |
Isoflurane blocks synaptic plasticity in the mouse hippocampus.
Topics: Aging; Anesthetics, Inhalation; Animals; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro T | 2001 |
Limitations of monastral blue as a vascular label: rapid rate of clearance is age-dependent, and interactions with anesthetics depress arterial blood pressure in rats.
Topics: Aging; Anesthetics; Animals; Blood Pressure; Coloring Agents; Drug Interactions; Halothane; Indoles; | 1992 |
Blood concentrations of sevoflurane and isoflurane on recovery from anaesthesia.
Topics: Adolescent; Adult; Aged; Aging; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics; Eth | 1992 |
Halothane blocks low-voltage-activated calcium current in rat sensory neurons.
Topics: Aging; Animals; Animals, Newborn; Calcium Channels; Evoked Potentials; Ganglia, Spinal; Halothane; I | 1991 |
Age affects the pharmacokinetics of inhaled anesthetics in humans.
Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Aging; Anesthesia, Inhalation; Anesthetics; Body Wei | 1991 |
Clinical characteristics of desflurane in surgical patients: minimum alveolar concentration.
Topics: Adult; Aging; Anesthesia Recovery Period; Anesthesia, Inhalation; Desflurane; Humans; Isoflurane; Mi | 1991 |
Arterial washin of halothane and isoflurane in young and elderly adult patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anesthesia, General; Anesthesia, Inhalation; Fema | 1991 |
Developmental changes in effects of halothane and isoflurane on contractile properties of rabbit cardiac skinned fibers.
Topics: Adenosine Triphosphatases; Aging; Animals; Animals, Newborn; Calcium; Embryonic and Fetal Developmen | 1990 |
Pharmacokinetics and pharmacodynamics of doxacurium in young and elderly patients during isoflurane anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, Inhalation; Hemodynamics; Humans; Isoflurane; Isoquinolines; Middle | 1990 |
Bupivacaine toxicity in young pigs is age-dependent and is affected by volatile anesthetics.
Topics: Aging; Animals; Arrhythmias, Cardiac; Blood Pressure; Bupivacaine; Cardiac Output; Drug Interactions | 1990 |
Influence of anesthetic induction with halothane and isoflurane on internal carotid blood flow velocity in early infancy.
Topics: Aging; Anesthesia; Blood Pressure; Carbon Dioxide; Carotid Arteries; Cerebrovascular Circulation; Fe | 1989 |
Solubility of I-653, sevoflurane, isoflurane, and halothane in human tissues.
Topics: Aged; Aging; Anesthetics; Chromatography, Gas; Desflurane; Ethers; Halothane; Humans; Isoflurane; Me | 1989 |
[Influence of isoflurane on the neuromuscular block induced by vecuronium in the child].
Topics: Adolescent; Aging; Child; Child, Preschool; Drug Synergism; Humans; Infant; Isoflurane; Neuromuscula | 1988 |
Electroencephalographic burst suppression in elderly and young patients anesthetized with isoflurane.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Anesthesia, General; Electroencephalography; Female; Hu | 1989 |
[Washout curve of isoflurane in adult and aged patients].
Topics: Adult; Aged; Aging; Anesthesia, Inhalation; Humans; Isoflurane; Middle Aged; Pulmonary Alveoli; Time | 1988 |
Effect of age on the solubility of volatile anesthetics in human tissues.
Topics: Adipose Tissue; Adult; Aged; Aging; Anesthesia, Inhalation; Brain; Enflurane; Halothane; Humans; Inf | 1986 |
Effect of temperature and age on the solubility of enflurane, halothane, isoflurane, and methoxyflurane in human blood.
Topics: Adult; Aged; Aging; Chromatography, Gas; Enflurane; Halothane; Humans; Isoflurane; Methoxyflurane; M | 1985 |