Page last updated: 2024-10-29

isoflurane and Acute Pain

isoflurane has been researched along with Acute Pain in 1 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Acute Pain: Intensely discomforting, distressful, or agonizing sensation associated with trauma or disease, with well-defined location, character, and timing.

Research Excerpts

ExcerptRelevanceReference
"Opioid receptor antagonists increase hyperalgesia in humans and animals, which indicates that endogenous activation of opioid receptors provides relief from acute pain; however, the mechanisms of long-term opioid inhibition of pathological pain have remained elusive."1.39Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence. ( Corder, G; Donahue, RR; Doolen, S; He, Y; Hu, X; Jutras, BL; McCarson, KE; Mogil, JS; Storm, DR; Taylor, BK; Wang, ZJ; Wieskopf, JS; Winter, MK, 2013)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Corder, G1
Doolen, S1
Donahue, RR1
Winter, MK1
Jutras, BL1
He, Y1
Hu, X1
Wieskopf, JS1
Mogil, JS1
Storm, DR1
Wang, ZJ1
McCarson, KE1
Taylor, BK1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury. A Randomized, Placebo-controlled, Double-blind Crossover Study[NCT02684669]Phase 280 participants (Actual)Interventional2016-02-29Completed
Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperal-gesia in Patients Following Recovery From Impacted Mandibular Third Molar Extraction. A Randomized, Placebo-controlled, Double-blind Crossover Study.[NCT02976337]Phase 214 participants (Anticipated)Interventional2017-10-12Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for isoflurane and Acute Pain

ArticleYear
Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.
    Science (New York, N.Y.), 2013, Sep-20, Volume: 341, Issue:6152

    Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Anima

2013
Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.
    Science (New York, N.Y.), 2013, Sep-20, Volume: 341, Issue:6152

    Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Anima

2013
Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.
    Science (New York, N.Y.), 2013, Sep-20, Volume: 341, Issue:6152

    Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Anima

2013
Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.
    Science (New York, N.Y.), 2013, Sep-20, Volume: 341, Issue:6152

    Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Anima

2013