isoflurane has been researched along with Acute Liver Injury, Drug-Induced in 81 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hepatic ischemia induced significant degree of I/R injuries in both isoflurane and sevoflurane non-IP groups." | 7.85 | Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats. ( Gwak, MS; Han, S; Jeong, JS; Kim, D; Kim, GS; Kim, KY; Ko, JS; Ryu, S; Shin, BS, 2017) |
| "A previously healthy but obese 26-yr-old woman was diagnosed as having hepatic dysfunction 17 days after the third of three consecutive exposures to isoflurane anesthesia for paranasal sinus surgery." | 7.68 | Fulminant hepatic failure after repeated exposure to isoflurane anesthesia: a case report. ( Brunt, EM; Holtmann, B; Marsh, JW; Peters, MG; White, H, 1991) |
| "Hypoxia, phenobarbital induction, and halothane anesthesia have been implicated in the pathogenesis of hepatotoxicity in the rat model." | 7.67 | Comparative toxicity of halothane, isoflurane, hypoxia, and phenobarbital induction in monolayer cultures of rat hepatocytes. ( Costa, AK; Heffel, DF; Schieble, TM; Trudell, JR, 1988) |
| "Four members of the Anesthetic and Life Support Advisory Committee of the Food and Drug Administration assessed the contribution of isoflurane (Forane) to 45 instances of hepatic dysfunction after isoflurane anesthesia reported to the FDA for 1981-1984." | 7.67 | Hepatic dysfunction after isoflurane anesthesia. ( Blitt, CD; Cohen, PJ; Merin, RG; Stoelting, RK, 1987) |
| "8% enflurane, or 1% halothane in 21% oxygen (air) for two hours resulted in hepatic centrilobular necrosis." | 7.66 | Isoflurane and enflurane-induced hepatic necrosis in triiodothyronine-pretreated rats. ( Berman, ML; Holaday, DA; Kuhnert, L; Phythyon, JM, 1983) |
| "A 76-year-old Caucasian woman developed fulminant hepatic necrosis 6 days after an uneventful operation under isoflurane anaesthesia." | 4.80 | Fatal hepatotoxicity after re-exposure to isoflurane: a case report and review of the literature. ( Beringer, TR; O'Rourke, D; Scott, GO; Turner, GB, 2000) |
| "Hepatic ischemia induced significant degree of I/R injuries in both isoflurane and sevoflurane non-IP groups." | 3.85 | Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats. ( Gwak, MS; Han, S; Jeong, JS; Kim, D; Kim, GS; Kim, KY; Ko, JS; Ryu, S; Shin, BS, 2017) |
| "A previously healthy but obese 26-yr-old woman was diagnosed as having hepatic dysfunction 17 days after the third of three consecutive exposures to isoflurane anesthesia for paranasal sinus surgery." | 3.68 | Fulminant hepatic failure after repeated exposure to isoflurane anesthesia: a case report. ( Brunt, EM; Holtmann, B; Marsh, JW; Peters, MG; White, H, 1991) |
| "Hypoxia, phenobarbital induction, and halothane anesthesia have been implicated in the pathogenesis of hepatotoxicity in the rat model." | 3.67 | Comparative toxicity of halothane, isoflurane, hypoxia, and phenobarbital induction in monolayer cultures of rat hepatocytes. ( Costa, AK; Heffel, DF; Schieble, TM; Trudell, JR, 1988) |
| "Four members of the Anesthetic and Life Support Advisory Committee of the Food and Drug Administration assessed the contribution of isoflurane (Forane) to 45 instances of hepatic dysfunction after isoflurane anesthesia reported to the FDA for 1981-1984." | 3.67 | Hepatic dysfunction after isoflurane anesthesia. ( Blitt, CD; Cohen, PJ; Merin, RG; Stoelting, RK, 1987) |
| "8% enflurane, or 1% halothane in 21% oxygen (air) for two hours resulted in hepatic centrilobular necrosis." | 3.66 | Isoflurane and enflurane-induced hepatic necrosis in triiodothyronine-pretreated rats. ( Berman, ML; Holaday, DA; Kuhnert, L; Phythyon, JM, 1983) |
| "Isoflurane is a volatile anaesthetic that has been commonly used since 1980." | 1.39 | Effects of isoflurane in an intoxication model: experimental study. ( Arici, A; Arici, S; Dogru, S; Karaman, S; Karaman, T; Kaya, Z; Suren, M; Tapar, H, 2013) |
| "A case of fulminant hepatic failure two days following an uneventful operation during isoflurane anesthesia is presented." | 1.38 | Isoflurane hepatitis-induced liver failure: a case report. ( Agrawal, A; Basnyat, PS; Morris, JE; Peiris, LJ, 2012) |
| "In halothane-treated females, plasma concentration of tumor necrosis factor-alpha was greater than in males, and neutrophils were recruited to liver more rapidly and to a greater extent." | 1.36 | A mouse model of severe halothane hepatitis based on human risk factors. ( Dugan, CM; Ganey, PE; MacDonald, AE; Roth, RA, 2010) |
| "Isoflurane was included for comparative purposes." | 1.28 | Sevoflurane is biotransformed by guinea pig liver slices but causes minimal cytotoxicity. ( Brendel, K; Fernando, J; Gandolfi, AJ; Ghantous, HN, 1992) |
| "Isoflurane anesthesia was given for the placement of a catheter into the femoral artery." | 1.27 | Effects of halothane, isoflurane, enflurane, thiopental, and fentanyl on blood gas values in rats exposed to hypoxia. ( Eger, EI; Johnson, BH; Lurz, FW; Shingu, K; Taber, V, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (41.98) | 18.7374 |
| 1990's | 23 (28.40) | 18.2507 |
| 2000's | 12 (14.81) | 29.6817 |
| 2010's | 12 (14.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Jeong, JS | 1 |
| Kim, D | 1 |
| Kim, KY | 1 |
| Ryu, S | 1 |
| Han, S | 1 |
| Shin, BS | 1 |
| Kim, GS | 1 |
| Gwak, MS | 1 |
| Ko, JS | 1 |
| Arici, S | 1 |
| Karaman, S | 1 |
| Dogru, S | 1 |
| Arici, A | 1 |
| Karaman, T | 1 |
| Tapar, H | 1 |
| Suren, M | 1 |
| Kaya, Z | 1 |
| Lin, J | 1 |
| Moore, D | 1 |
| Hockey, B | 1 |
| Di Lernia, R | 1 |
| Gorelik, A | 1 |
| Liew, D | 1 |
| Nicoll, A | 1 |
| Wang, H | 1 |
| Wang, L | 3 |
| Li, NL | 1 |
| Li, JT | 1 |
| Yu, F | 1 |
| Zhao, YL | 1 |
| Yi, J | 1 |
| Bian, JF | 1 |
| Chen, JH | 1 |
| Yuan, SF | 1 |
| Wang, T | 1 |
| Lv, YG | 1 |
| Liu, NN | 1 |
| Zhu, XS | 1 |
| Ling, R | 1 |
| Yun, J | 1 |
| Arslan, A | 1 |
| Kuyrukluyildiz, U | 1 |
| Binici, O | 1 |
| Cetin, N | 1 |
| Balci, MG | 1 |
| Kuzucu, M | 1 |
| Yilmaz, A | 1 |
| Altuner, D | 1 |
| Coban, TA | 1 |
| Her, C | 1 |
| Dugan, CM | 1 |
| MacDonald, AE | 1 |
| Roth, RA | 1 |
| Ganey, PE | 1 |
| Kim, M | 2 |
| Park, SW | 1 |
| D'Agati, VD | 1 |
| Lee, HT | 1 |
| Yuan, Z | 1 |
| Liu, J | 1 |
| Liang, X | 1 |
| Lin, D | 1 |
| Mahboobi, N | 1 |
| Esmaeili, S | 1 |
| Safari, S | 1 |
| Habibollahi, P | 1 |
| Dabbagh, A | 1 |
| Alavian, SM | 1 |
| Peiris, LJ | 1 |
| Agrawal, A | 1 |
| Morris, JE | 1 |
| Basnyat, PS | 1 |
| Wark, HJ | 1 |
| Pageaux, GP | 1 |
| Chung, PC | 1 |
| Chiou, SC | 1 |
| Lien, JM | 1 |
| Li, AH | 1 |
| Wong, CH | 1 |
| Chidiac, EJ | 1 |
| Tung, D | 1 |
| Yoshida, EM | 1 |
| Wang, CS | 1 |
| Steinbrecher, UP | 1 |
| Anderson, JS | 1 |
| Rose, NR | 1 |
| Martin, JL | 4 |
| Eger, EI | 11 |
| Njoku, DB | 2 |
| Côté, G | 1 |
| Bouchard, S | 1 |
| Marier, JR | 1 |
| Plummer, JL | 1 |
| Beckwith, AL | 1 |
| Bastin, FN | 1 |
| Adams, JF | 1 |
| Cousins, MJ | 2 |
| Hall, P | 1 |
| Shingu, K | 1 |
| Johnson, BH | 4 |
| Lurz, FW | 1 |
| Taber, V | 1 |
| McLaughlin, DF | 1 |
| Jurdi-Nuwayhid, F | 1 |
| Fassoulaki, A | 2 |
| Ferrell, LD | 2 |
| Smuckler, EA | 3 |
| Cahalan, MK | 3 |
| Eger, RR | 2 |
| Harper, MH | 4 |
| Gelman, S | 1 |
| Rimerman, V | 1 |
| Fowler, KC | 1 |
| Bishop, SP | 1 |
| Bradley, EL | 1 |
| Corall, IM | 1 |
| Berman, ML | 1 |
| Kuhnert, L | 1 |
| Phythyon, JM | 1 |
| Holaday, DA | 1 |
| Van Dyke, RA | 3 |
| Vandam, LD | 1 |
| Collins, P | 1 |
| Johnson, B | 1 |
| Biava, C | 1 |
| Kenna, JG | 2 |
| Jones, RM | 2 |
| Plevak, DJ | 2 |
| Flannery, KD | 1 |
| Charlton, M | 1 |
| Poterucha, JJ | 1 |
| Humphreys, CE | 1 |
| Derfus, G | 1 |
| Pohl, LR | 3 |
| Lee, NC | 1 |
| Shiraishi, N | 1 |
| Saito, H | 1 |
| Shiraishi, H | 1 |
| Saeki, S | 1 |
| Ogawa, S | 1 |
| Suzuki, H | 1 |
| Scheider, DM | 1 |
| Klygis, LM | 1 |
| Tsang, TK | 1 |
| Caughron, MC | 1 |
| Slayter, KL | 1 |
| Sketris, IS | 1 |
| Gulanikar, A | 1 |
| Gunaratnam, NT | 1 |
| Benson, J | 1 |
| Gandolfi, AJ | 2 |
| Chen, M | 1 |
| Bito, H | 2 |
| Ikeda, K | 1 |
| Larsen, R | 1 |
| Sinha, A | 1 |
| Clatch, RJ | 1 |
| Stuck, G | 1 |
| Blumenthal, SA | 1 |
| Patel, SA | 1 |
| Njoku, D | 1 |
| Laster, MJ | 2 |
| Gong, DH | 1 |
| Reed, GF | 1 |
| Gong, D | 1 |
| Koblin, DD | 1 |
| Bowland, T | 1 |
| Ionescu, P | 2 |
| Weiskopf, RB | 2 |
| Merin, RG | 2 |
| Brown, JL | 1 |
| Meldrum, DJ | 1 |
| Griffiths, R | 1 |
| Berghaus, TM | 1 |
| Baron, A | 1 |
| Geier, A | 1 |
| Lamerz, R | 1 |
| Paumgartner, G | 1 |
| Granados Llamas, LM | 1 |
| Navas Rivera, E | 1 |
| Marenco de la Fuente, ML | 1 |
| Balanza Ortiz, R | 1 |
| Suárez Collazos, F | 1 |
| Puente Egido, JJ | 1 |
| Turner, GB | 1 |
| O'Rourke, D | 1 |
| Scott, GO | 1 |
| Beringer, TR | 1 |
| Keegan, MT | 1 |
| Vasdev, GM | 1 |
| Nyberg, SL | 1 |
| Bourdi, M | 1 |
| Malnick, SD | 1 |
| Mahlab, K | 1 |
| Borchardt, J | 1 |
| Sokolowski, N | 1 |
| Attali, M | 1 |
| Shrestha, S | 1 |
| Soloway, R | 1 |
| Duray, PR | 1 |
| Tsokos, M | 1 |
| Abu-Asab, MS | 1 |
| West, AB | 1 |
| Cohen, EN | 1 |
| Ghantous, HN | 1 |
| Fernando, J | 1 |
| Brendel, K | 1 |
| Yasuda, N | 1 |
| Freire, B | 1 |
| Peterson, N | 1 |
| Lockhart, SH | 1 |
| Rampil, IJ | 1 |
| Laster, M | 1 |
| Diamond, JG | 1 |
| Power, SJ | 1 |
| Bajorek, PK | 1 |
| Munday, I | 1 |
| Brunt, EM | 1 |
| White, H | 1 |
| Marsh, JW | 1 |
| Holtmann, B | 1 |
| Peters, MG | 1 |
| Zimmerman, H | 1 |
| Allan, LG | 2 |
| Hussey, AJ | 2 |
| Howie, J | 1 |
| Beckett, GJ | 2 |
| Smith, AF | 1 |
| Hayes, JD | 1 |
| Drummond, GB | 1 |
| D'Eramo, C | 1 |
| Ghinelli, F | 1 |
| Zuccoli, P | 1 |
| Fisher, NA | 1 |
| Iwata, RT | 1 |
| Cherng, CH | 1 |
| Ho, ST | 1 |
| Chen, CF | 1 |
| Kuo, WS | 1 |
| Yang, CY | 1 |
| Chang, CL | 1 |
| Aldridge, LM | 1 |
| Paul, D | 1 |
| Ray, DC | 1 |
| Schieble, TM | 1 |
| Costa, AK | 1 |
| Heffel, DF | 1 |
| Trudell, JR | 1 |
| Gil, F | 1 |
| Fiserova-Bergerova, V | 1 |
| Altman, NH | 1 |
| Stoelting, RK | 2 |
| Becker, GL | 1 |
| Miletich, DJ | 1 |
| Albrecht, RF | 1 |
| Carrigan, TW | 1 |
| Straughen, WJ | 1 |
| Blogg, C | 1 |
| Grégoire, S | 1 |
| Smiley, RK | 1 |
| Webster, JA | 1 |
| Blitt, CD | 1 |
| Cohen, PJ | 1 |
| Luu, KC | 1 |
| Luciana, S | 1 |
| Chao, CC | 1 |
| Stock, JG | 1 |
| Strunin, L | 1 |
| Lunam, CA | 1 |
| Hall, PD | 1 |
12 reviews available for isoflurane and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Halothane: how should it be used in a developing country?
Topics: Anesthetics, Inhalation; Attitude of Health Personnel; Chemical and Drug Induced Liver Injury; Costs | 2012 |
Desflurane vs. sevoflurane--a review.
Topics: Anesthesia, Inhalation; Anesthesiology; Anesthetics, Inhalation; Carbon Monoxide Poisoning; Central | 2004 |
Halogenated hydrocarbon environmental pollution: the special case of halogenated anesthetics.
Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Ethers; Halothane; Health Occupations; Humans; | 1982 |
Self-assessment questions true or false?
Topics: Adolescent; Aged; Anesthesia; Anesthesia, Inhalation; Anesthesiology; Anesthetics; Anesthetics, Loca | 1980 |
The organ toxicity of inhaled anesthetics.
Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Disease Models | 1995 |
The use of volatile agents in southern Africa.
Topics: Chemical and Drug Induced Liver Injury; Drug Costs; Enflurane; Halothane; Humans; Incidence; Informe | 1994 |
Inhalation anaesthetics and liver damage.
Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Enflurane; Halothane; Humans; Isoflu | 1993 |
Isoflurane hepatotoxicity: a case report and review of the literature.
Topics: Aged; Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Biopsy; Chemical a | 1996 |
[Metabolism and toxicity of anesthetics].
Topics: Anesthetics, Inhalation; Carbon Monoxide Poisoning; Chemical and Drug Induced Liver Injury; Enfluran | 1999 |
Fatal hepatotoxicity after re-exposure to isoflurane: a case report and review of the literature.
Topics: Aged; Amputation, Surgical; Anesthesia, General; Anesthetics, Inhalation; Chemical and Drug Induced | 2000 |
Toxicity of inhalation anaesthetic agents.
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Drug Hypersens | 1978 |
Unexplained hepatitis following halothane.
Topics: Adult; Age Factors; Anesthesia, General; Animals; Biotransformation; Chemical and Drug Induced Liver | 1985 |
3 trials available for isoflurane and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Renal and hepatic function in surgical patients after low-flow sevoflurane or isoflurane anesthesia.
Topics: Adult; Aged; Alanine Transaminase; Anesthesia, General; Anesthetics, Inhalation; Aspartate Aminotran | 1996 |
[Mobilization of alpha-glutathione S-transferase in the anesthetized patient].
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthesia, General; Anesthetics; Anesthetics, Inhala | 1999 |
Hepatic glutathione S-transferase release after halothane anaesthesia: open randomised comparison with isoflurane.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Clin | 1987 |
66 other studies available for isoflurane and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats.
Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Ischemia; Ischemic Precond | 2017 |
Effects of isoflurane in an intoxication model: experimental study.
Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Isoflurane; Kidney; Liver; | 2013 |
Drug-induced hepatotoxicity: incidence of abnormal liver function tests consistent with volatile anaesthetic hepatitis in trauma patients.
Topics: Adult; Alanine Transaminase; Anesthesia; Anesthetics; Chemical and Drug Induced Liver Injury; Desflu | 2014 |
Subanesthetic isoflurane reduces zymosan-induced inflammation in murine Kupffer cells by inhibiting ROS-activated p38 MAPK/NF-κB signaling.
Topics: Anesthetics; Animals; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chemokines; Cyclooxyg | 2014 |
Can thıamıne pyrophosphate prevent desflurane ınduced hepatotoxıcıty ın rats?
Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Chemical and Dr | 2016 |
Acetaminophen-induced, not desflurane-induced, hepatotoxicity.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Anti-Ulcer Agents; Chemical and Dr | 2008 |
A mouse model of severe halothane hepatitis based on human risk factors.
Topics: Age Factors; Anesthetics, Inhalation; Animals; Blotting, Western; Chemical and Drug Induced Liver In | 2010 |
Isoflurane activates intestinal sphingosine kinase to protect against bilateral nephrectomy-induced liver and intestine dysfunction.
Topics: Acute Kidney Injury; Alanine Transaminase; Anesthetics, Inhalation; Animals; Apoptosis; Chemical and | 2011 |
Serum biochemical indicators of hepatobiliary function in dogs following prolonged anaesthesia with sevoflurane or isoflurane.
Topics: Alanine Transaminase; Alkaline Phosphatase; Anesthetics, Inhalation; Animals; Aspartate Aminotransfe | 2012 |
Isoflurane hepatitis-induced liver failure: a case report.
Topics: Aged; Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Fatal Outcome; Female; Humans | 2012 |
Hepatic failure after cardiopulmonary bypass is unlikely to be isoflurane hepatitis.
Topics: Aged; Anesthetics, Inhalation; Cardiopulmonary Bypass; Chemical and Drug Induced Liver Injury; Human | 2002 |
[Non-viral fulminant hepatitis].
Topics: Adult; Anesthetics, Inhalation; Breast Implantation; Causality; Chemical and Drug Induced Liver Inju | 2003 |
Reproducible hepatic dysfunction following separate anesthesia with sevoflurane and desflurane.
Topics: Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Desflurane; Humans; Isoflurane; Mal | 2003 |
Severe desflurane hepatotoxicity after colon surgery in an elderly patient.
Topics: Aged; Aged, 80 and over; Anesthesia, Inhalation; Anesthetics, Inhalation; Chemical and Drug Induced | 2005 |
Desflurane hepatitis associated with hapten and autoantigen-specific IgG4 antibodies.
Topics: Adult; Autoantibodies; Autoantigens; Chemical and Drug Induced Liver Injury; Desflurane; Female; Hap | 2007 |
Hepatotoxicity after desflurane anesthesia in a 15-month-old child with Mobius syndrome after previous exposure to isoflurane.
Topics: Androstanols; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Antifibrinolyt | 2007 |
Free radical formation in vivo and hepatotoxicity due to anesthesia with halothane.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclic N-Oxides; Electron Spi | 1982 |
Effects of halothane, isoflurane, enflurane, thiopental, and fentanyl on blood gas values in rats exposed to hypoxia.
Topics: Anesthetics; Animals; Carbon Dioxide; Chemical and Drug Induced Liver Injury; Enflurane; Fentanyl; H | 1983 |
Repeated isoflurane anesthesia in a patient with hepatic dysfunction.
Topics: Aged; Chemical and Drug Induced Liver Injury; Common Bile Duct Diseases; Diagnosis, Differential; Fe | 1984 |
Untoward side effects and toxicities of inhalational anesthetics.
Topics: Anesthesia, Inhalation; Anesthetics; Carcinogens; Chemical and Drug Induced Liver Injury; Enflurane; | 1984 |
Isoflurane does not prevent hepatic injury produced by halothane in rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Enzyme Induction; Halothane; Isoflurane; Male; Meth | 1984 |
The effect of halothane, isoflurane, and blood loss on hepatotoxicity and hepatic oxygen availability in phenobarbital-pretreated hypoxic rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Halothane; Hemorrhage; Isoflurane; Liver; Liver Cir | 1984 |
Isoflurane: the need for new volatile agents.
Topics: Anesthesia, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Halothane; Humans; Isoflura | 1983 |
Celiac plexus block does not alter hepatic injury in rats.
Topics: Anesthetics; Animals; Bupivacaine; Celiac Plexus; Chemical and Drug Induced Liver Injury; Drug Inter | 1984 |
Isoflurane and enflurane-induced hepatic necrosis in triiodothyronine-pretreated rats.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Eating; Enflurane; Halothane; Hyperthy | 1983 |
Metabolism of anesthetic agents: toxic implications.
Topics: Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Enflurane; Enzyme Induction; Fasting; | 1982 |
Hepatic Injury following halothane, enflurane, and isoflurane anesthesia in rats.
Topics: Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Enflurane; Enzyme Induction; Halothane | 1982 |
Hepatic centrilobular necrosis in rats after exposure to halothane, enflurane, or isoflurane.
Topics: Animals; Chemical and Drug Induced Liver Injury; Enflurane; Glutathione; Halothane; Isoflurane; Live | 1982 |
Toxic metabolites from biotransformation: major organ damage.
Topics: Anesthetics; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Enflurane; Ether; H | 1981 |
Hepatotoxicity after desflurane anesthesia.
Topics: Aged; Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Desflurane; Female; Humans; I | 1995 |
[A case of liver dysfunction after isoflurane anesthesia].
Topics: Aged; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Female; Humans; Isoflurane | 1993 |
Hepatic dysfunction after repeated isoflurane administration.
Topics: Chemical and Drug Induced Liver Injury; Female; Humans; Isoflurane; Liver Function Tests; Middle Age | 1993 |
Halothane hepatitis in a renal transplant patient previously exposed to isoflurane.
Topics: Adult; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Halothane; Humans; Isoflurane | 1993 |
Suspected isoflurane hepatitis in an obese patient with a history of halothane hepatitis.
Topics: Chemical and Drug Induced Liver Injury; Cross Reactions; Halothane; Humans; Isoflurane; Male; Middle | 1995 |
[Halothane-induced hepatitis].
Topics: Chemical and Drug Induced Liver Injury; Enflurane; Halothane; Humans; Isoflurane; Liver | 1996 |
Biotransformation of halothane, enflurane, isoflurane, and desflurane to trifluoroacetylated liver proteins: association between protein acylation and hepatic injury.
Topics: Acylation; Anesthetics, Inhalation; Animals; Antigen-Antibody Reactions; Biotransformation; Chemical | 1997 |
Dose-related biochemical markers of renal injury after sevoflurane versus desflurane anesthesia in volunteers.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Biomarkers; Chemical and Drug Induced Liver Inj | 1997 |
Anesthesiology.
Topics: Anesthesiology; Anesthetics, Inhalation; Anesthetics, Local; Bupivacaine; Chemical and Drug Induced | 1998 |
Gallstones and isoflurane hepatitis.
Topics: Aged; Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Cholelithiasis; Drug Hypersen | 1998 |
Hepatotoxicity following desflurane anesthesia.
Topics: Adult; Anesthesia; Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Desflurane; Fema | 1999 |
Fatal hepatitis associated with isoflurane exposure and CYP2A6 autoantibodies.
Topics: Anesthetics, Inhalation; Aryl Hydrocarbon Hydroxylases; Autoantibodies; Chemical and Drug Induced Li | 2001 |
Acute cholestatic hepatitis after exposure to isoflurane.
Topics: Acetylcysteine; Acute Disease; Aged; Anesthetics, Inhalation; Biopsy; Chemical and Drug Induced Live | 2002 |
Subcellular localization of trifluoroacetylated liver proteins in association with hepatitis following isoflurane.
Topics: Aged; Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Endarterectomy, Carotid; Huma | 2002 |
Sevoflurane is biotransformed by guinea pig liver slices but causes minimal cytotoxicity.
Topics: 1-Propanol; Anesthetics; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Ethers; | 1992 |
Desflurane does not produce hepatic or renal injury in human volunteers.
Topics: Adult; Anesthetics; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Desflurane; Hum | 1992 |
A prospective study of liver function in infants and children exposed to daily isoflurane for several weeks.
Topics: Alkaline Phosphatase; Anesthesia, General; Aspartate Aminotransferases; Bilirubin; Chemical and Drug | 1991 |
Fulminant hepatic failure after repeated exposure to isoflurane anesthesia: a case report.
Topics: Adult; Anesthesia; Chemical and Drug Induced Liver Injury; Female; Humans; Isoflurane; Liver; Liver | 1991 |
Even isoflurane.
Topics: Anesthesia; Chemical and Drug Induced Liver Injury; Enflurane; Halothane; Humans; Isoflurane | 1991 |
[Hepatic injury and halogenated anesthetics: preliminary clinical experience].
Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Ha | 1985 |
Hepatic necrosis associated with herpes virus after isoflurane anesthesia.
Topics: Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Herpesviridae Infections; Humans; I | 1985 |
[Acute hepatitis in an uremic patient following isoflurane anesthesia].
Topics: Adult; Anesthesia, Inhalation; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Female; Huma | 1988 |
Plasma glutathione S-transferase concentration as a measure of hepatocellular integrity following a single general anaesthetic with halothane, enflurane or isoflurane.
Topics: Adult; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Enflurane; Female; Glutathion | 1988 |
Comparative toxicity of halothane, isoflurane, hypoxia, and phenobarbital induction in monolayer cultures of rat hepatocytes.
Topics: Animals; Cell Survival; Chemical and Drug Induced Liver Injury; Halothane; Hypoxia; In Vitro Techniq | 1988 |
Hepatic protection from chemical injury by isoflurane.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug | 1988 |
Isoflurane and postoperative hepatic dysfunction.
Topics: Adult; Chemical and Drug Induced Liver Injury; Humans; Isoflurane; Liver Diseases; Postoperative Com | 1987 |
Halogenated anesthetics increase oxygen consumption in isolated hepatocytes from phenobarbital-treated rats.
Topics: Anesthetics; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 En | 1987 |
A report of hepatic necrosis and death following isoflurane anesthesia.
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Isoflurane; Liver; Necrosis | 1987 |
[Volatile anesthetics other than halothane].
Topics: Chemical and Drug Induced Liver Injury; Enflurane; Humans; Isoflurane; Kidney; Liver; Liver Function | 1987 |
Acute hepatitis in a patient with mild factor IX deficiency after anesthesia with isoflurane.
Topics: Adult; Anesthesia, General; Chemical and Drug Induced Liver Injury; Hemophilia B; Humans; Isoflurane | 1986 |
Acute hepatitis after isoflurane anesthesia.
Topics: Acute Disease; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Humans; Isoflurane | 1986 |
Hepatic dysfunction after isoflurane anesthesia.
Topics: Adolescent; Adult; Age Factors; Anesthesia; Chemical and Drug Induced Liver Injury; Female; Humans; | 1987 |
Minimal hepatic and renal function changes after isoflurane anesthesia.
Topics: Adult; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Female; Humans; Isoflurane; K | 1985 |
Guinea-pig model of halothane-associated hepatotoxicity in the absence of enzyme induction and hypoxia.
Topics: Animals; Biotransformation; Blood Gas Analysis; Chemical and Drug Induced Liver Injury; Disease Mode | 1985 |
Nitrous oxide does not hinder the repair of halothane-induced hepatic injury in the rat.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Bretylium Compounds; Chemical an | 1985 |