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isoflurane and Acute Kidney Injury

isoflurane has been researched along with Acute Kidney Injury in 12 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
"The volatile anesthetic isoflurane protects against renal ischemia and reperfusion injury by releasing renal tubular TGF-β1."7.79The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury. ( Brown, KM; D'Agati, VD; Ham, A; Kim, JY; Kim, M; Lee, HT, 2013)
"Isoflurane releases renal tubular transforming growth factor-β1 (TGF-β1) and protects against ischemic acute kidney injury."7.79Critical role of interleukin-11 in isoflurane-mediated protection against ischemic acute kidney injury in mice. ( Brown, KM; D'Agati, VD; Ham, A; Kim, JY; Kim, M; Lee, HT; Yeh, J, 2013)
"The volatile anesthetic isoflurane protects against renal ischemia and reperfusion injury by releasing renal tubular TGF-β1."3.79The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury. ( Brown, KM; D'Agati, VD; Ham, A; Kim, JY; Kim, M; Lee, HT, 2013)
" show that isoflurane uses a tubule-based transforming growth factor-β/CD73-dependent process that generates adenosine to protect mice from ischemic acute kidney injury (AKI) with effects to prevent the 'no-reflow phenomenon' and decrease inflammation."3.79The conundrum of protection from AKI by adenosine in rodent clamp ischemia models. ( Venkatachalam, MA; Weinberg, JM, 2013)
"Isoflurane releases renal tubular transforming growth factor-β1 (TGF-β1) and protects against ischemic acute kidney injury."3.79Critical role of interleukin-11 in isoflurane-mediated protection against ischemic acute kidney injury in mice. ( Brown, KM; D'Agati, VD; Ham, A; Kim, JY; Kim, M; Lee, HT; Yeh, J, 2013)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's4 (33.33)18.2507
2000's0 (0.00)29.6817
2010's6 (50.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Steiger, C1
Phan, NV1
Huang, HW1
Sun, H1
Chu, JN1
Reker, D1
Gwynne, D1
Collins, J1
Tamang, S1
McManus, R1
Lopes, A1
Hayward, A1
Baron, RM1
Kim, EY1
Traverso, G1
Kim, M6
Ham, A2
Kim, JY2
Brown, KM2
D'Agati, VD4
Lee, HT4
Venkatachalam, MA1
Weinberg, JM1
Yeh, J1
Su, MW1
Chang, SS1
Chen, CH1
Huang, CC1
Chang, SW1
Tsai, YC1
Lam, CF1
Park, SW2
Tanigami, H1
Yahagi, N1
Kumon, K1
Watanabe, Y1
Haruna, M1
Matsui, J1
Hayashi, H1
Tung, A1
Jacobsohn, E1
Lochhead, KM1
Kharasch, ED1
Zager, RA1
Breheny, FX1
Kendall, PA1
Piper, C1
Dörner, O1
Zadkovic, N1
Remmele, W1
von Egidy, H1

Trials

1 trial available for isoflurane and Acute Kidney Injury

ArticleYear
Long-term sedation with isoflurane in postoperative intensive care in cardiac surgery.
    Artificial organs, 1997, Volume: 21, Issue:1

    Topics: Acute Kidney Injury; Adult; Anesthetics, Inhalation; Cardiac Surgical Procedures; Child; Female; Flu

1997

Other Studies

11 other studies available for isoflurane and Acute Kidney Injury

ArticleYear
Dynamic Monitoring of Systemic Biomarkers with Gastric Sensors.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021, Volume: 8, Issue:24

    Topics: Acute Kidney Injury; Anesthetics, Inhalation; Animals; Biomarkers; Disease Models, Animal; Gastric J

2021
The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury.
    Kidney international, 2013, Volume: 84, Issue:1

    Topics: 5'-Nucleotidase; Acute Kidney Injury; Adenosine; Anesthetics, Inhalation; Animals; Antibodies, Neutr

2013
The conundrum of protection from AKI by adenosine in rodent clamp ischemia models.
    Kidney international, 2013, Volume: 84, Issue:1

    Topics: 5'-Nucleotidase; Acute Kidney Injury; Anesthetics, Inhalation; Animals; GPI-Linked Proteins; Humans;

2013
Critical role of interleukin-11 in isoflurane-mediated protection against ischemic acute kidney injury in mice.
    Anesthesiology, 2013, Volume: 119, Issue:6

    Topics: Acute Kidney Injury; Analysis of Variance; Anesthesia; Anesthetics, Inhalation; Animals; Apoptosis;

2013
Preconditioning renoprotective effect of isoflurane in a rat model of virtual renal transplant.
    The Journal of surgical research, 2014, Jun-01, Volume: 189, Issue:1

    Topics: Acetylcysteine; Acute Kidney Injury; Anesthetics, Inhalation; Animals; Free Radical Scavengers; Isch

2014
Isoflurane activates intestinal sphingosine kinase to protect against bilateral nephrectomy-induced liver and intestine dysfunction.
    American journal of physiology. Renal physiology, 2011, Volume: 300, Issue:1

    Topics: Acute Kidney Injury; Alanine Transaminase; Anesthetics, Inhalation; Animals; Apoptosis; Chemical and

2011
Isoflurane activates intestinal sphingosine kinase to protect against renal ischemia-reperfusion-induced liver and intestine injury.
    Anesthesiology, 2011, Volume: 114, Issue:2

    Topics: Acute Kidney Injury; Anesthetics, Inhalation; Animals; Enzyme Activation; Intestinal Diseases; Intes

2011
A case of nonoliguric renal failure after general anesthesia with sevoflurane and desflurane.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:6

    Topics: Acute Kidney Injury; Adult; Anesthesia, General; Anesthetics, Inhalation; Desflurane; Ethers; Humans

1997
Anesthetic effects on the glycerol model of rhabdomyolysis-induced acute renal failure in rats.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:2

    Topics: Acute Kidney Injury; Anesthetics, Inhalation; Animals; Creatine Kinase; Creatinine; Desflurane; Glyc

1998
Use of isoflurane for sedation in intensive care.
    Critical care medicine, 1992, Volume: 20, Issue:7

    Topics: Acute Kidney Injury; Cognition Disorders; Fenthion; Humans; Hypnotics and Sedatives; Isoflurane; Leg

1992
[Acute fluorine-induced kidney failure following isoflurane with fatal organ oxalosis].
    Medizinische Klinik (Munich, Germany : 1983), 1987, Aug-21, Volume: 82, Issue:17

    Topics: Acute Kidney Injury; Anesthesia, Inhalation; Femoral Neck Fractures; Humans; Isoflurane; Kidney; Mal

1987