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isoflurane and Active Hyperemia

isoflurane has been researched along with Active Hyperemia in 12 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Research Excerpts

ExcerptRelevanceReference
"Despite intense investigation, the mechanism of isoflurane-induced cerebral hyperemia is unclear."7.71Isoflurane-induced cerebral hyperemia is partially mediated by nitric oxide and epoxyeicosatrienoic acids in mice in vivo. ( Farber, NE; Hudetz, AG; Kampine, JP; Kehl, F; Moreno, C; Roman, RJ; Shen, H, 2002)
"The mechanism of isoflurane-induced cerebral hyperemia is poorly understood."7.69Nitric oxide and prostanoids contribute to isoflurane-induced cerebral hyperemia in pigs. ( Helfaer, MA; Kirsch, JR; McPherson, RW; Moore, LE; Tobin, JR; Traystman, RJ, 1994)
"Nitric oxide (NO) has been reported to play an important role in isoflurane-induced cerebral hyperemia in vivo."7.69Isoflurane-induced cerebral hyperemia in neuronal nitric oxide synthase gene deficient mice. ( Ayata, C; Bosnjak, ZJ; Huang, PL; Hudetz, AG; Kampine, JP; Ma, J; Meng, W; Moskowitz, MA; Okamoto, H; Roman, RJ, 1997)
"Adenosine and high-concentration isoflurane are commonly used to induce hyperemia for assessment of coronary flow reserve (CFR) in mice, but high-concentration isoflurane may exacerbate cardiac dysfunction, leading to impaired CFR."3.78Comparison between adenosine and isoflurane for assessing the coronary flow reserve in mouse models of left ventricular pressure and volume overload. ( Ge, J; Wu, J; You, J; Zou, Y, 2012)
"Despite intense investigation, the mechanism of isoflurane-induced cerebral hyperemia is unclear."3.71Isoflurane-induced cerebral hyperemia is partially mediated by nitric oxide and epoxyeicosatrienoic acids in mice in vivo. ( Farber, NE; Hudetz, AG; Kampine, JP; Kehl, F; Moreno, C; Roman, RJ; Shen, H, 2002)
"The mechanism of isoflurane-induced cerebral hyperemia is poorly understood."3.69Nitric oxide and prostanoids contribute to isoflurane-induced cerebral hyperemia in pigs. ( Helfaer, MA; Kirsch, JR; McPherson, RW; Moore, LE; Tobin, JR; Traystman, RJ, 1994)
"Nitric oxide (NO) has been reported to play an important role in isoflurane-induced cerebral hyperemia in vivo."3.69Isoflurane-induced cerebral hyperemia in neuronal nitric oxide synthase gene deficient mice. ( Ayata, C; Bosnjak, ZJ; Huang, PL; Hudetz, AG; Kampine, JP; Ma, J; Meng, W; Moskowitz, MA; Okamoto, H; Roman, RJ, 1997)
"Halothane was compared to isoflurane and the question of whether major surgery might reduce FAR was investigated."1.27Isoflurane has a greater margin of safety than halothane in swine with and without major surgery or critical coronary stenosis. ( Gilbert, M; Roberts, SL; Tinker, JH, 1987)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's5 (41.67)18.2507
2000's4 (33.33)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, XY1
Zhou, SJ1
Yu, YF1
Shen, YF1
Xu, HZ1
You, J1
Wu, J1
Ge, J1
Zou, Y1
Kehl, F1
Shen, H1
Moreno, C1
Farber, NE1
Roman, RJ2
Kampine, JP3
Hudetz, AG3
Hartley, CJ1
Reddy, AK1
Madala, S1
Michael, LH1
Entman, ML1
Taffet, GE1
Moore, LE3
Kirsch, JR3
Helfaer, MA1
Tobin, JR1
McPherson, RW3
Traystman, RJ2
Lee, JG1
Smith, JJ1
Bosnjak, ZJ2
Sturaitis, MK1
Okamoto, H1
Meng, W1
Ma, J1
Ayata, C1
Huang, PL1
Moskowitz, MA1
Tibble, RK1
Girling, KJ1
Mahajan, RP1
Endoh, H1
Honda, T1
Ohashi, S1
Hida, S1
Roberts, SL1
Gilbert, M1
Tinker, JH1

Trials

1 trial available for isoflurane and Active Hyperemia

ArticleYear
A comparison of the transient hyperemic response test and the static autoregulation test to assess graded impairment in cerebral autoregulation during propofol, desflurane, and nitrous oxide anesthesia.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:1

    Topics: Adolescent; Adult; Algorithms; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalat

2001

Other Studies

11 other studies available for isoflurane and Active Hyperemia

ArticleYear
Cerebral hyperaemia after isoflurane anaesthesia for craniotomy of patients with supratentorial brain tumour.
    Acta anaesthesiologica Scandinavica, 2013, Volume: 57, Issue:10

    Topics: Adult; Anesthesia, Inhalation; Arterial Pressure; Cerebrovascular Circulation; Craniotomy; Female; H

2013
Comparison between adenosine and isoflurane for assessing the coronary flow reserve in mouse models of left ventricular pressure and volume overload.
    American journal of physiology. Heart and circulatory physiology, 2012, Nov-15, Volume: 303, Issue:10

    Topics: Adenosine; Animals; Coronary Circulation; Disease Models, Animal; Echocardiography, Doppler; Feasibi

2012
Isoflurane-induced cerebral hyperemia is partially mediated by nitric oxide and epoxyeicosatrienoic acids in mice in vivo.
    Anesthesiology, 2002, Volume: 97, Issue:6

    Topics: Animals; Arachidonic Acids; Blood Gas Analysis; Blood Pressure; Brain; Cerebrovascular Circulation;

2002
Doppler estimation of reduced coronary flow reserve in mice with pressure overload cardiac hypertrophy.
    Ultrasound in medicine & biology, 2008, Volume: 34, Issue:6

    Topics: Anesthetics; Animals; Aortic Valve; Blood Flow Velocity; Cardiomegaly; Coronary Vessels; Hyperemia;

2008
Nitric oxide and prostanoids contribute to isoflurane-induced cerebral hyperemia in pigs.
    Anesthesiology, 1994, Volume: 80, Issue:6

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Carbon Dioxide; Cerebrovascular Circulation; F

1994
Effects of volatile anesthetics on cerebrocortical laser Doppler flow: hyperemia, autoregulation, carbon dioxide response, flow oscillations, and role of nitric oxide.
    Advances in pharmacology (San Diego, Calif.), 1994, Volume: 31

    Topics: Anesthetics; Animals; Arginine; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; Haloth

1994
A cholinergic agonist induces cerebral hyperemia in isoflurane- but not pentobarbital-anesthetized dogs.
    Anesthesia and analgesia, 1994, Volume: 78, Issue:5

    Topics: Anesthesia; Animals; Brain; Dogs; Ganglionic Stimulants; Hemodynamics; Hyperemia; Isoflurane; Oxotre

1994
N omega-nitro-L-arginine methyl ester prevents cerebral hyperemia by inhaled anesthetics in dogs.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Arginine; Brain; Dogs; Halothane; Hyperemia; Isoflurane; NG-Nitroar

1993
Isoflurane-induced cerebral hyperemia in neuronal nitric oxide synthase gene deficient mice.
    Anesthesiology, 1997, Volume: 86, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Brain; Cerebrovascular Circulation; Dose-Response Relationship, Dr

1997
[Cerebral autoregulation during sevoflurane or isoflurane anesthesia: evaluation with transient hyperemic response].
    Masui. The Japanese journal of anesthesiology, 2001, Volume: 50, Issue:12

    Topics: Adult; Anesthetics, Inhalation; Blood Flow Velocity; Cerebrovascular Circulation; Female; Homeostasi

2001
Isoflurane has a greater margin of safety than halothane in swine with and without major surgery or critical coronary stenosis.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:6

    Topics: Animals; Coronary Disease; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Halothane

1987