Page last updated: 2024-10-29

isoflurane and Ache

isoflurane has been researched along with Ache in 100 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Research Excerpts

ExcerptRelevanceReference
" Clinical investigations have revealed that isoflurane anesthesia is efficient to alleviate pain during cardiac surgery, including heart bypass surgery."7.88Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery. ( Lin, H; Pi, Z; Yang, J, 2018)
"F 13640 is a newly discovered high-efficacy 5-HT(1A) receptor agonist that produces exceptional analgesia in animal models of tonic and chronic, nociceptive and neuropathic pains by novel molecular and neuroadaptive mechanisms."7.73The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain. ( Bardin, L; Colpaert, FC; Degryse, AD; Gomez de Segura, IA; Kiss, I, 2005)
"The authors previously reported changes in electroencephalographic bicoherence during isoflurane anesthesia combined with epidural anesthesia."7.72Electroencephalographic bicoherence is sensitive to noxious stimuli during isoflurane or sevoflurane anesthesia. ( Hagihira, S; Mashimo, T; Mori, T; Takashina, M; Ueyama, H, 2004)
"After tracheal intubation and femoral arterial cannulation, bilateral neck dissections were performed to isolate the external carotid arteries and external jugular veins."5.29Does the brain influence somatic responses to noxious stimuli during isoflurane anesthesia? ( Antognini, JF; Borges, M, 1994)
"4%) or apnea (11 of 78, 14."5.19A phase I, dose-escalation trial evaluating the safety and efficacy of emulsified isoflurane in healthy human volunteers. ( Huang, H; Li, R; Liao, T; Liu, J; Yi, X; Zhang, W, 2014)
"Propofol and isoflurane requirements and preoperative pain scores were not different between groups."5.17Comparison of perioperative analgesic efficacy between methadone and butorphanol in cats. ( Bauquier, SH; Beths, T; Holm, M; Warne, LN, 2013)
"The significant reduction in MAC of isoflurane supported the practice of the addition of regional anesthesia for painful dental procedures to reduce the dose-dependent cardiorespiratory effects of general anesthesia."5.17Effect of mepivacaine in an infraorbital nerve block on minimum alveolar concentration of isoflurane in clinically normal anesthetized dogs undergoing a modified form of dental dolorimetry. ( Snyder, CJ; Snyder, LB, 2013)
" Desflurane, with the characteristics of rapid onset and minimal metabolism, may provide better analgesia and safety for labour pain control."5.08Desflurane analgesia for vaginal delivery. ( Abboud, TK; Donovan, MM; Peres Da Silva, E; Swart, F; Yakal, K; Zhu, J, 1995)
" Clinical investigations have revealed that isoflurane anesthesia is efficient to alleviate pain during cardiac surgery, including heart bypass surgery."3.88Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery. ( Lin, H; Pi, Z; Yang, J, 2018)
" In this study, we examined 3 commonly used euthanasia methods in mice: intraperitoneal injection of pentobarbital-phenytoin solution, CO2 inhalation, and isoflurane anesthesia followed by CO2 inhalation."3.85Physiologic, Behavioral, and Histologic Responses to Various Euthanasia Methods in C57BL/6NTac Male Mice. ( Boivin, GP; Bottomley, MA; Goss, L; Grobe, N; Schiml, PA, 2017)
" After having established the mice model of hypnosis and analgesia by intraperitoneal injections of appropriate doses of enflurane, isoflurane or sevoflurane, we intracerebroventricularly or intrathecally injected different doses of nicotine and then observed the effects on the sleeping time using awaken test and the pain threshold in hot-plate test (HPPT) using hot-plate test."3.75Nicotinic acetylcholine receptors mediate the hypnotic and analgesic effects of emulsified inhalation anesthetics. ( Dai, TJ; Yan, S; Zeng, YM, 2009)
"The experimental setup consisted of a randomized block design with four experimental groups: two light (3/4) minimum alveolar concentration (MAC) isoflurane anesthesia groups (unstimulated/NIWR-stimulated) and two NIWR-stimulated surgical anesthesia groups (1(1/2) MAC isoflurane anesthesia and (3/4) MAC isoflurane anesthesia combined with fentanyl 400-600 microg x kg(-1) x h(-1))."3.74Suppression of noxious-induced c-fos expression in the rat lumbar spinal cord by isoflurane alone or combined with fentanyl. ( Nguyen, NK; Ritskes-Hoitinga, M; Sommers, MG; van Egmond, J; Veening, JG; Vissers, KC, 2008)
" After having established the mouse model of analgesia by intraperitoneal or subcutaneous injections of appropriate doses of emulsified enflurane, isoflurane or sevoflurane, we injected different doses of AMPA intrathecally and observed effects on the pain threshold using the hot-plate and acetic acid-induced writhing tests."3.74Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics. ( Dai, TJ; Hang, LH; Shao, DH; Yang, YH; Zeng, YM, 2007)
"F 13640 is a newly discovered high-efficacy 5-HT(1A) receptor agonist that produces exceptional analgesia in animal models of tonic and chronic, nociceptive and neuropathic pains by novel molecular and neuroadaptive mechanisms."3.73The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain. ( Bardin, L; Colpaert, FC; Degryse, AD; Gomez de Segura, IA; Kiss, I, 2005)
"The authors previously reported changes in electroencephalographic bicoherence during isoflurane anesthesia combined with epidural anesthesia."3.72Electroencephalographic bicoherence is sensitive to noxious stimuli during isoflurane or sevoflurane anesthesia. ( Hagihira, S; Mashimo, T; Mori, T; Takashina, M; Ueyama, H, 2004)
"The NMDA receptor and the NK-1 receptor are important determinants of the MAC of isoflurane, exerting this influence by inhibition of pain transmission in the spinal cord, while mGlu and AMPA receptors have no effect on the MAC of isoflurane."3.70Intrathecal co-administration of NMDA antagonist and NK-1 antagonist reduces MAC of isoflurane in rats. ( Goto, F; Ishizaki, K; Karasawa, S; Nara, T; Obata, H; Sasaki, M, 1999)
"The purpose of this study was to examine the anaesthetic requirement of intrathecal midazolam in a dose-response fashion in isoflurane-anaesthetized, tracheostomized rats, and to evaluate the apnoeic threshold after each intrathecal midazolam dose."3.69Intrathecal midazolam reduces isoflurane MAC and increases the apnoeic threshold in rats. ( Forster, A; Jorge-Costa, M; Morel, DR; Pizzolato, GP; Schwieger, IM, 1994)
"In 26 patients, the end-tidal and corresponding arterial isoflurane concentrations needed to suppress eye opening to verbal command and motor response after trapezius squeeze, 50 Hz electric tetanic stimulation, laryngoscopy, skin incision, and tracheal intubation in 50% of all patients were determined."3.69Anesthetic depth defined using multiple noxious stimuli during isoflurane/oxygen anesthesia. I. Motor reactions. ( Lauber, R; Maggiorini, M; Minder, CE; Petersen-Felix, S; Thomson, DA; Zbinden, AM, 1994)
"Isoflurane used as a sole agent is unable to suppress hemodynamic reactions (blood pressure and heart rate) to painful stimuli."3.69Anesthetic depth defined using multiple noxious stimuli during isoflurane/oxygen anesthesia. II. Hemodynamic responses. ( Petersen-Felix, S; Thomson, DA; Zbinden, AM, 1994)
"These results suggest that the NK-1 receptor plays an important role in determining the MAC of isoflurane by inhibition of pain transmission in the spinal cord."3.69Intrathecal neurokinin-1 receptor antagonist reduces isoflurane MAC in rats. ( Goto, F; Hasegawa, M; Ishizaki, K; Karasawa, S; Takahashi, K, 1997)
"Mice treated with ethyl chloride spray, isoflurane and buprenorphine, and 2-point local nerve blocks demonstrated increased tail-flick latency compared with that of untreated mice."2.77Evaluation of common anesthetic and analgesic techniques for tail biopsy in mice. ( Carver, S; Jones, CP; Kendall, LV, 2012)
"Isoflurane 0."2.67Isoflurane in labour. ( Hasan, MA; Thomas, TA; Wee, MY, 1993)
"Isoflurane is a useful agent for prolonged sedation of ventilated patients and does not have any adverse effect on the cardiorespiratory system or on hepatic, renal or adrenal function."2.67Isoflurane for prolonged sedation in the intensive care unit; efficacy and safety. ( Spencer, EM; Willatts, SM, 1992)
"Isoflurane is a fluorinated ether used primarily as an inhalation anesthetic."2.39Providing comfort to critically ill pediatric patients: isoflurane. ( Curley, MA; Molengraft, JA, 1995)
"Our study suggests that approaches to activate the orexin system can be beneficial in postoperative recovery."1.48Activation of orexin system facilitates anesthesia emergence and pain control. ( Bickler, PE; Cheung, K; Guan, Z; Jan, LY; Kurien, PA; Kyu, S; Wang, L; Zhou, W, 2018)
"Intraoperative awareness and postoperative nausea/vomiting were assessed at follow-up."1.46Total intravenous anesthesia produces outcomes superior to those with combined intravenous-inhalation anesthesia for laparoscopic gynecological surgery at high altitude. ( Li, H; Peng, Q; Xu, R; Xu, S; Yang, J; Zhang, G; Zhang, Q; Zhou, S, 2017)
"Increasingly more aged people with Alzheimer's disease (AD) must undergo surgery with general anesthesia for various reasons."1.40Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice. ( Deng, Y; He, Z; Lu, B; Qi, B; Su, D; Tian, J; Wang, X; Xu, H; Zheng, B, 2014)
"Sevoflurane MAC was not significantly reduced by N2O and its antinociceptive action was almost completely abolished in KOP-knockout (KO) mice."1.40κ-Opioid receptor mediates the antinociceptive effect of nitrous oxide in mice. ( Fukagawa, H; Fukuda, K; Koyama, T, 2014)
"Isoflurane has been used as an inhaled anaesthetic for nearly 30 years."1.37Effects of intrathecal isoflurane administration on nociception and Fos expression in the rat spinal cord. ( Duan, QZ; Li, YQ; Liu, CR; Wang, W; Wei, YY; Wu, SX; Xu, LX; Zhang, H, 2011)
" This relatively simple blood collection technique seems to be efficient and safe in hamsters."1.35Efficiency and safety of a technique for drawing blood from the hamster cranial vena cava. ( Benito, PJ; García-Olmo, DC; Picazo, MG, 2009)
"Lidocaine was administered IV to each cat to achieve target pseudo-steady-state plasma concentrations of 0, 3, 5, 7 9, and 11 microg/mL, and isoflurane concentration was reduced to an equipotent concentration."1.33Assessment of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats. ( Ilkiw, JE; Pypendop, BH, 2005)
"Isoflurane MAC was not changed by intrathecal ondansetron in rats or systemically administered ondansetron in P-gp knockout mice."1.33The pronociceptive effect of ondansetron in the setting of P-glycoprotein inhibition. ( Flood, P; Scott, JA; Wood, M, 2006)
"Isoflurane was maintained at 0."1.31Propofol directly depresses lumbar dorsal horn neuronal responses to noxious stimulation in goats. ( Antognini, JF; Carstens, E; Piercy, M; Wang, XW, 2000)
"After tracheal intubation and femoral arterial cannulation, bilateral neck dissections were performed to isolate the external carotid arteries and external jugular veins."1.29Does the brain influence somatic responses to noxious stimuli during isoflurane anesthesia? ( Antognini, JF; Borges, M, 1994)
"Isoflurane concentration was adjusted up and down, and the EEG and movement response to tail clamp were assessed at each level until the minimum alveolar concentration was determined in each rat."1.28No correlation between quantitative electroencephalographic measurements and movement response to noxious stimuli during isoflurane anesthesia in rats. ( Laster, MJ; Rampil, IJ, 1992)

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-19903 (3.00)18.7374
1990's27 (27.00)18.2507
2000's39 (39.00)29.6817
2010's27 (27.00)24.3611
2020's4 (4.00)2.80

Authors

AuthorsStudies
Matta, JA1
Cornett, PM1
Miyares, RL1
Abe, K1
Sahibzada, N1
Ahern, GP1
Seyfi, S1
Amiri, HA1
Banihashem, N1
Ezoji, K1
Ziaei, SG1
Davis, JA1
Bopp, AC1
Henwood, MK1
Bean, P1
Grau, JW1
Lykholt, LED1
Mørch, CD1
Jensen, W1
Shirai, T1
Yano, M1
Natsume, T1
Awaga, Y1
Itani, Y1
Hama, A1
Matsuda, A1
Takamatsu, H1
Boivin, GP1
Bottomley, MA1
Schiml, PA1
Goss, L1
Grobe, N1
Ryu, K1
Song, K1
Kim, J3
Kim, E1
Kim, SH1
Pi, Z1
Lin, H1
Yang, J2
Zhou, W1
Cheung, K1
Kyu, S1
Wang, L1
Guan, Z1
Kurien, PA1
Bickler, PE1
Jan, LY1
Voigt, AM1
Bergfeld, C1
Beyerbach, M1
Kästner, SB1
Warne, LN1
Beths, T1
Holm, M1
Bauquier, SH1
Xu, H1
Lu, B1
Zheng, B1
Tian, J1
Qi, B1
Deng, Y1
He, Z1
Su, D1
Wang, X1
Huang, H1
Li, R1
Liu, J1
Zhang, W1
Liao, T1
Yi, X1
Sadler, KE1
Stratton, JM1
DeBerry, JJ1
Kolber, BJ1
Fan, HG1
Jiang, S1
Lin, DQ1
Lu, DZ1
Li, L1
Ji, W1
Li, WZ1
Fukagawa, H1
Koyama, T1
Fukuda, K2
Wang, LW1
Zhou, MY1
Jian, HW1
Dai, TJ4
Jaber, SM1
Sullivan, S1
Hankenson, FC1
Kilbaugh, TJ1
Margulies, SS1
Kim, HC1
Hong, WP1
Lim, YJ1
Park, HP1
Barletta, M1
Quandt, J1
Hofmeister, E1
Xu, R1
Zhou, S1
Li, H1
Zhang, Q1
Zhang, G1
Xu, S1
Peng, Q1
Ge, ZJ1
Tan, YF1
Zhao, YP1
Cui, GX1
Asanuma, T1
Yasui, H1
Sato, M1
Inanami, O1
Kuwabara, M1
Yan, S1
Zeng, YM4
Cheng, W1
Yin, Q1
Wang, S1
Chen, HS1
Feng, T1
Picazo, MG1
Benito, PJ1
García-Olmo, DC1
Pham, TM1
Hagman, B1
Codita, A1
Van Loo, PL1
Strömmer, L1
Baumans, V1
Guan, Y1
Raja, SN1
Liu, CR1
Duan, QZ1
Wang, W1
Wei, YY1
Zhang, H1
Li, YQ1
Wu, SX1
Xu, LX1
Kung, HH1
Hsu, SF1
Hung, YC1
Chen, KB1
Chen, JY1
Wen, YR1
Sun, WZ1
Walker, KA1
Mellish, JE1
Weary, DM1
Shu, Y1
Zhou, Z1
Wan, Y1
Sanders, RD1
Li, M1
Pac-Soo, CK1
Maze, M1
Ma, D1
Young, MJ1
Alston, TA1
Valentine, H1
Williams, WO1
Maurer, KJ1
Moldal, ER1
Kirpensteijn, J1
Kristensen, AT1
Haga, HA1
Nødtvedt, A1
Eriksen, T1
Snyder, CJ1
Snyder, LB1
Jones, CP1
Carver, S1
Kendall, LV1
Jinks, SL3
Antognini, JF14
Martin, JT1
Jung, S1
Carstens, E10
Atherley, R3
Eger, EI3
Xing, Y1
Laster, MJ2
Sonner, JM2
Valverde, A1
Morey, TE1
Hernández, J1
Davies, W1
Hagihira, S1
Takashina, M1
Mori, T1
Ueyama, H1
Mashimo, T2
Stekiel, TA1
J Contney, S1
Bosnjak, ZJ1
Kampine, JP1
Roman, RJ1
Stekiel, WJ1
Rowley, TJ1
Daniel, D1
Flood, P3
Pypendop, BH1
Ilkiw, JE1
Kiss, I1
Degryse, AD1
Bardin, L1
Gomez de Segura, IA1
Colpaert, FC1
Spadavecchia, C1
Levionnois, O1
Kronen, PW1
Leandri, M1
Spadavecchia, L1
Schatzmann, U1
Scott, JA1
Wood, M1
Mitsuyo, T1
Dutton, RC1
Hayashida, M1
Fukunaga, A1
Sakurai, S1
Mamiya, H1
Ichinohe, T1
Kaneko, Y1
Hanaoka, K1
Vahle-Hinz, C1
Detsch, O1
Hackner, C1
Kochs, E1
Otto, KA1
Chen, Y1
Werner, DF1
Homanics, GE1
Lin, CM1
Wu, CT1
Lee, ST1
Lui, TN1
Huang, CC1
Li, AH1
Doufas, AG1
Hang, LH1
Shao, DH1
Yang, YH1
Yao, A1
Ihmsen, H1
Schywalsky, M1
Plettke, R1
Priller, M1
Walz, F1
Schwilden, H1
Sommers, MG1
Nguyen, NK1
Veening, JG1
Vissers, KC1
Ritskes-Hoitinga, M1
van Egmond, J1
Shaw, MV1
Naff, KA1
LeBlanc, S1
Swing, SP1
Roberts, JS1
O'Donnell, D1
Emerson, C1
Berg, K1
Kien, ND1
Curley, MA1
Molengraft, JA1
Petersen-Felix, S4
Arendt-Nielsen, L2
Bak, P2
Roth, D1
Fischer, M2
Bjerring, P2
Zbinden, AM4
Abboud, TK1
Swart, F1
Zhu, J1
Donovan, MM1
Peres Da Silva, E1
Yakal, K1
Lysko, GS1
Robinson, JL1
Casto, R1
Ferrone, RA1
Borges, M1
Abram, SE1
Olson, EE1
Schwieger, IM1
Jorge-Costa, M1
Pizzolato, GP1
Forster, A1
Morel, DR1
Maggiorini, M1
Lauber, R1
Thomson, DA2
Minder, CE1
Wee, MY1
Hasan, MA1
Thomas, TA1
Tomi, K1
Tashiro, C1
Yagi, M1
Pak, M1
Nishimura, S1
Nishimura, M1
Yoshiya, I1
Ishizaki, K2
Karasawa, S2
Takahashi, K1
Hasegawa, M1
Goto, F2
Sonner, J1
Li, J1
Yost, CS1
Hampson, AJ1
Leonoudakis, D1
Koblin, DD1
Bornheim, LM1
Gray, AT1
Chae, BK1
Lee, HW1
Sun, K1
Choi, YH1
Kim, HM1
Saitoh, Y1
Fujii, Y1
Makita, K1
Tanaka, H1
Amaha, K1
Ben-Shlomo, I1
Moskovich, R1
Katz, Y1
Shalev, E1
Sasaki, M1
Obata, H1
Nara, T1
Dahan, A1
Teppema, L1
Wang, XW3
Piercy, M1
Masaki, E1
Ebisawa, T1
Kondo, I1
Hayashida, K1
Matsumoto, Y1
Kawamura, M1
Sudo, M1
Sudo, S1
Zhang, Y1
Laster, M1
Kendig, JJ1
Machin, KL1
Livingston, A1
Rampil, IJ1
Spencer, EM1
Willatts, SM1
Ghouri, AF1
Bodner, M1
White, PF1
Gibbs, NM1
Larach, DR1
Schuler, HG1
Wren, WS1
Alteri, S1
Beruschi, M1
Bolli, L1
Fazio, R1
Maddaloni, G1
Mammarella, M1
Mammini, R1
Paesani, G1
Poli, P1
Riccardi, R1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Effects of Sevoflurane and Desflurane on Prevention of Catheter-related Bladder Discomfort[NCT02096224]108 participants (Actual)Interventional2014-05-31Completed
Topical Analgesia Before Inhalational Anaesthesia: A Retrospective Observational Study[NCT04959409]500 participants (Actual)Observational2020-08-01Completed
EEG to Monitor Propofol Anesthetic Depth in Infants and Toddlers[NCT05701748]120 participants (Anticipated)Interventional2023-02-03Recruiting
Efficacy and Safety of Methoxyflurane Vaporized (PENTHROX®) in the Treatment of Acute Trauma Pain in Pre-hospital Setting and in the Emergency Department in Italy: a Multicentre, Randomized, Controlled, Open-label Study[NCT03585374]Phase 3272 participants (Actual)Interventional2018-02-08Completed
Effect of Perioperative Epidural Block and Dexamethasone on Outcome of Patients Undergoing Pancreatic Cancer Surgery: a 2×2 Factorial Randomized Controlled Trial[NCT04025840]Phase 4260 participants (Anticipated)Interventional2019-09-11Recruiting
Effect of Transversus Abdominis Plane (TAP) Block and the Perioperative Stress Response: Randomized Control Trial in Patient Undergoing Total Abdominal Hysterectomy in a Tertiary Care Hospital of Pakistan[NCT03443271]Phase 450 participants (Actual)Interventional2016-06-17Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for isoflurane and Ache

ArticleYear
Providing comfort to critically ill pediatric patients: isoflurane.
    Critical care nursing clinics of North America, 1995, Volume: 7, Issue:2

    Topics: Child; Conscious Sedation; Drug Monitoring; Humans; Intensive Care Units, Pediatric; Isoflurane; Pai

1995

Trials

24 trials available for isoflurane and Ache

ArticleYear
An Investigation Into Quality of Recovery After General Anesthesia With Isoflurane and Propofol in Patients Undergoing Abdominal Hysterectomy.
    Asian journal of anesthesiology, 2022, 09-01, Volume: 60, Issue:3

    Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; Female; Humans; Hysterect

2022
Comparison of the Analgesic Properties of Sevoflurane and Desflurane Using Surgical Pleth Index at Equi-Minimum Alveolar Concentration.
    International journal of medical sciences, 2017, Volume: 14, Issue:10

    Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Arthroscopy; Brachial Plexus Block; Desflura

2017
Effects of isoflurane with and without dexmedetomidine or remifentanil on heart rate variability before and after nociceptive stimulation at different multiples of minimum alveolar concentration in dogs.
    American journal of veterinary research, 2013, Volume: 74, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics,

2013
Comparison of perioperative analgesic efficacy between methadone and butorphanol in cats.
    Journal of the American Veterinary Medical Association, 2013, Sep-15, Volume: 243, Issue:6

    Topics: Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Butorphanol; Cat Disea

2013
A phase I, dose-escalation trial evaluating the safety and efficacy of emulsified isoflurane in healthy human volunteers.
    Anesthesiology, 2014, Volume: 120, Issue:3

    Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Apnea; Cohort Studies; Dose-Response Relati

2014
Comparison of anaesthetic and analgesic effects of emulsified isoflurane used alone or combined with lidocaine and fentanyl in dogs.
    New Zealand veterinary journal, 2014, Volume: 62, Issue:3

    Topics: Analgesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Animals; Dogs; Dru

2014
The effect of sevoflurane versus desflurane on postoperative catheter-related bladder discomfort in patients undergoing transurethral excision of a bladder tumour: a randomized controlled trial.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2016, Volume: 63, Issue:5

    Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Desflurane; Female; Humans; Incidence; Isofluran

2016
Determination of minimum alveolar concentration of isoflurane in dogs and cats using the up-and-down method. A preliminary study.
    Research in veterinary science, 2016, Volume: 106

    Topics: Anesthetics, Inhalation; Animals; Cats; Dogs; Dose-Response Relationship, Drug; Female; Isoflurane;

2016
Evaluation of inflammatory and hemostatic surgical stress responses in male cats after castration under general anesthesia with or without local anesthesia.
    American journal of veterinary research, 2012, Volume: 73, Issue:11

    Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Animals; Cats; I

2012
Effect of mepivacaine in an infraorbital nerve block on minimum alveolar concentration of isoflurane in clinically normal anesthetized dogs undergoing a modified form of dental dolorimetry.
    Journal of the American Veterinary Medical Association, 2013, Jan-15, Volume: 242, Issue:2

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Animals; Dogs; Dose-Response Re

2013
Evaluation of common anesthetic and analgesic techniques for tail biopsy in mice.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2012, Volume: 51, Issue:6

    Topics: Analgesics; Anesthetics; Animals; Animals, Outbred Strains; Behavior, Animal; Biopsy; Bupivacaine; B

2012
Validation of several types of noxious stimuli for use in determining the minimum alveolar concentration for inhalation anesthetics in dogs and rabbits.
    American journal of veterinary research, 2003, Volume: 64, Issue:8

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dogs; Dose-Response Relationship, Drug; El

2003
Evaluation of administration of isoflurane at approximately the minimum alveolar concentration on depression of a nociceptive withdrawal reflex evoked by transcutaneous electrical stimulation in ponies.
    American journal of veterinary research, 2006, Volume: 67, Issue:5

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Electric Stimulation; Horses; Isoflurane;

2006
Effects of averaging data series on the electroencephalographic response to noxious visceral stimulation in isoflurane-anaesthetized dogs.
    Research in veterinary science, 2007, Volume: 83, Issue:3

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Pressure; Dogs; Electric Stimulation

2007
Sitting position does not alter minimum alveolar concentration for desflurane.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2007, Volume: 54, Issue:7

    Topics: Adult; Algorithms; Anesthetics, Inhalation; Blood Pressure; Computer Simulation; Data Interpretation

2007
Analgesic effect in humans of subanaesthetic isoflurane concentrations evaluated by experimentally induced pain.
    British journal of anaesthesia, 1995, Volume: 75, Issue:1

    Topics: Adult; Analgesia; Anesthetics, Inhalation; Cold Temperature; Dose-Response Relationship, Drug; Femal

1995
Desflurane analgesia for vaginal delivery.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:2

    Topics: Acid-Base Equilibrium; Adaptation, Physiological; Adult; Analgesia, Obstetrical; Anesthetics, Inhala

1995
Isoflurane in labour.
    Anaesthesia, 1993, Volume: 48, Issue:5

    Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Drug Combinations; Female;

1993
The effects of isoflurane on repeated nociceptive stimuli (central temporal summation).
    Pain, 1996, Volume: 64, Issue:2

    Topics: Adult; Anesthetics, Inhalation; Electric Stimulation; Electromyography; Female; Humans; Isoflurane;

1996
Modified double burst stimulation of varying stimulating currents.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:7

    Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Anesthetics, Inhalation; Electric Stimulati

1998
Midazolam/ketamine sedative combination compared with fentanyl/propofol/isoflurane anaesthesia for oocyte retrieval.
    Human reproduction (Oxford, England), 1999, Volume: 14, Issue:7

    Topics: Adult; Anesthesia, General; Anesthetics; Female; Fentanyl; Humans; Hypnotics and Sedatives; Isoflura

1999
Isoflurane for prolonged sedation in the intensive care unit; efficacy and safety.
    Intensive care medicine, 1992, Volume: 18, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Illness; Drug Monitoring; England; Female; Hemo

1992
Recovery profile after desflurane-nitrous oxide versus isoflurane-nitrous oxide in outpatients.
    Anesthesiology, 1991, Volume: 74, Issue:3

    Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Inhalation; Cognition

1991
[Evaluation of analgesic protection using RIA determination of prolactin, ACTH, cortisol and aldosterone during general anesthesia with enflurane-isoflurane and buprenorphine].
    Minerva anestesiologica, 1987, Volume: 53, Issue:11

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Anesthesia, General; Buprenorphine; Enflurane; Fema

1987

Other Studies

75 other studies available for isoflurane and Ache

ArticleYear
General anesthetics activate a nociceptive ion channel to enhance pain and inflammation.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Jun-24, Volume: 105, Issue:25

    Topics: Anesthetics, General; Animals; Ankyrins; Calcium Channels; Humans; Inflammation; Isoflurane; Mice; P

2008
General Anesthesia Blocks Pain-Induced Hemorrhage and Locomotor Deficits After Spinal Cord Injury in Rats.
    Journal of neurotrauma, 2023, Volume: 40, Issue:23-24

    Topics: Anesthesia, General; Anesthetics; Animals; Contusions; Hemorrhage; Humans; Isoflurane; Pain; Pentoba

2023
Differences in intracortical responses following non-noxious and noxious stimulation in anaesthetized rats.
    Brain research, 2023, 12-15, Volume: 1821

    Topics: Anesthesia; Animals; Electric Stimulation; Evoked Potentials; Isoflurane; Pain; Physical Stimulation

2023
Pharmacologic Modulation of Noxious Stimulus-evoked Brain Activation in Cynomolgus Macaques Observed with Functional Neuroimaging.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2020, 01-01, Volume: 59, Issue:1

    Topics: Analgesia; Analgesics; Animals; Brain; Female; Functional Neuroimaging; Isoflurane; Macaca fascicula

2020
Physiologic, Behavioral, and Histologic Responses to Various Euthanasia Methods in C57BL/6NTac Male Mice.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2017, Jan-01, Volume: 56, Issue:1

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Carbon Dioxide; Euthanasia, Animal; Hypnotics and Seda

2017
Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery.
    Molecular medicine reports, 2018, Volume: 17, Issue:5

    Topics: Animals; Apoptosis; Coronary Artery Bypass; Isoflurane; Male; Mice; Myocardial Ischemia; Myocardium;

2018
Activation of orexin system facilitates anesthesia emergence and pain control.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 11-06, Volume: 115, Issue:45

    Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Clozapine; Dependovirus; Electroenceph

2018
Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 39, Issue:1

    Topics: Aging; Alzheimer Disease; Analysis of Variance; Anesthetics, Inhalation; Animals; Desflurane; Diseas

2014
Optimization of a pain model: effects of body temperature and anesthesia on bladder nociception in mice.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Anesthesia; Animals; Body Temperature; Disease Models, Animal; Electrophysiological Phenomena; Femal

2013
κ-Opioid receptor mediates the antinociceptive effect of nitrous oxide in mice.
    British journal of anaesthesia, 2014, Volume: 113, Issue:6

    Topics: Analgesics, Non-Narcotic; Anesthetics, Inhalation; Animals; Isoflurane; Lumbar Vertebrae; Methyl Eth

2014
Relationship between gamma-hydroxybutyric acid receptors and the hypnotic and analgesic effects of emulsified inhalation anesthetics.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:16

    Topics: Analgesics; Anesthetics, Inhalation; Animals; Benzocycloheptenes; Enflurane; Female; Hot Temperature

2014
Comparison of Heart Rate and Blood Pressure with Toe Pinch and Bispectral Index for Monitoring the Depth of Anesthesia in Piglets.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2015, Volume: 54, Issue:5

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Biomedical Research; Blood Pressure; Female; Heart Rat

2015
Total intravenous anesthesia produces outcomes superior to those with combined intravenous-inhalation anesthesia for laparoscopic gynecological surgery at high altitude.
    The Journal of international medical research, 2017, Volume: 45, Issue:1

    Topics: Adolescent; Adult; Altitude; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Inhal

2017
Evidence that inhibition of spinal nitric oxide production contributes to the antinociceptive effects of emulsified isoflurane on formalin-induced pain in rats.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:10

    Topics: Analgesics; Animals; Emulsifying Agents; Female; Injections, Spinal; Isoflurane; Male; Nitric Oxide;

2008
A BOLD-fMRI study of cerebral activation induced by injection of algesic chemical substances into the anesthetized rat forepaw.
    The Japanese journal of veterinary research, 2008, Volume: 56, Issue:2

    Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Forelimb; Formaldehyde; Isoflurane; Magnetic R

2008
Nicotinic acetylcholine receptors mediate the hypnotic and analgesic effects of emulsified inhalation anesthetics.
    Fundamental & clinical pharmacology, 2009, Volume: 23, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Emulsions; Enflurane; Female; In

2009
Effects of intrathecal injection of nicotine on the analgesic effects of isoflurane in a model of inflammatory pain.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 105, Issue:2

    Topics: Analgesics; Animals; Formaldehyde; Injections, Spinal; Isoflurane; Mice; Nicotine; Pain; Pain Thresh

2009
Efficiency and safety of a technique for drawing blood from the hamster cranial vena cava.
    Lab animal, 2009, Volume: 38, Issue:6

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cricetinae; Female; Isoflurane; Male; Mesocricetus; Pa

2009
Housing environment influences the need for pain relief during post-operative recovery in mice.
    Physiology & behavior, 2010, Apr-19, Volume: 99, Issue:5

    Topics: Analgesics, Non-Narcotic; Anesthetics, Inhalation; Animals; Behavior, Animal; Body Weight; Disease M

2010
Wide-dynamic-range neurons are heterogeneous in windup responsiveness to changes in stimulus intensity and isoflurane anesthesia level in mice.
    Journal of neuroscience research, 2010, Aug-01, Volume: 88, Issue:10

    Topics: Action Potentials; Anesthetics, Inhalation; Animals; Electric Stimulation; Isoflurane; Male; Mice; M

2010
Effects of intrathecal isoflurane administration on nociception and Fos expression in the rat spinal cord.
    European journal of anaesthesiology, 2011, Volume: 28, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Exp

2011
Electroacupuncture analgesia, stress responses, and variations in sensitivity in rats anesthetized with different sub-MAC anesthetics.
    European journal of pain (London, England), 2011, Volume: 15, Issue:6

    Topics: Analgesia; Anesthetics, Inhalation; Animals; Blood Pressure; Electroacupuncture; Halothane; Heart Ra

2011
Effects of hot-iron branding on heart rate, breathing rate and behaviour of anaesthetised Steller sea lions.
    The Veterinary record, 2011, Oct-01, Volume: 169, Issue:14

    Topics: Anesthetics, Inhalation; Animal Identification Systems; Animal Welfare; Animals; Behavior, Animal; F

2011
Nociceptive stimuli enhance anesthetic-induced neuroapoptosis in the rat developing brain.
    Neurobiology of disease, 2012, Volume: 45, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Behavior, Animal; Blotting, Western;

2012
Does anesthetic technique influence cancer?
    Journal of clinical anesthesia, 2012, Volume: 24, Issue:1

    Topics: Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Female; Humans; I

2012
Sedation or inhalant anesthesia before euthanasia with CO2 does not reduce behavioral or physiologic signs of pain and stress in mice.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2012, Volume: 51, Issue:1

    Topics: Acepromazine; Adrenocorticotropic Hormone; Anesthesia; Animal Welfare; Animals; Animals, Laboratory;

2012
Isoflurane, but not halothane, depresses c-fos expression in rat spinal cord at concentrations that suppress reflex movement after supramaximal noxious stimulation.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Halothane; Immunohistochemistry;

2002
Alpha-2 adrenoreceptors probably do not mediate the immobility produced by inhaled anesthetics.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:6

    Topics: Adrenergic alpha-Antagonists; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Im

2003
Isoflurane depresses diffuse noxious inhibitory controls in rats between 0.8 and 1.2 minimum alveolar anesthetic concentration.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:1

    Topics: Action Potentials; Anesthetics, Inhalation; Animals; Cold Temperature; Dose-Response Relationship, D

2003
Electroencephalographic bicoherence is sensitive to noxious stimuli during isoflurane or sevoflurane anesthesia.
    Anesthesiology, 2004, Volume: 100, Issue:4

    Topics: Adult; Aged; Anesthesia; Anesthetics, Inhalation; Electroencephalography; Female; Fentanyl; Humans;

2004
Reversal of minimum alveolar concentrations of volatile anesthetics by chromosomal substitution.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Chromosomes; Gene Transfer Techniques; Haloth

2004
The role of adrenergic and cholinergic transmission in volatile anesthetic-induced pain enhancement.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:4

    Topics: Adrenergic alpha-Antagonists; Algorithms; Anesthetics, Inhalation; Animals; Benzylamines; Dopamine;

2005
Assessment of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats.
    American journal of veterinary research, 2005, Volume: 66, Issue:4

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Blood Pressure; Cats

2005
The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain.
    European journal of pharmacology, 2005, Oct-31, Volume: 523, Issue:1-3

    Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Anesthetics, Inhalati

2005
The pronociceptive effect of ondansetron in the setting of P-glycoprotein inhibition.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Female; Isoflurane; Male; Mice; Mi

2006
The differential effects of halothane and isoflurane on windup of dorsal horn neurons selected in unanesthetized decerebrated rats.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Area Under Curve; Dose-Response Relationship, Drug; Halothane; Iso

2006
The characteristics of intravenous adenosine-induced antinociception in a rabbit model of acute nociceptive pain: a comparative study with remifentanil.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:4

    Topics: Adenosine; Analgesics; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Blood Pressure; Carbon

2006
Corresponding minimum alveolar concentrations of isoflurane and isoflurane/nitrous oxide have divergent effects on thalamic nociceptive signalling.
    British journal of anaesthesia, 2007, Volume: 98, Issue:2

    Topics: Anesthetics, Combined; Anesthetics, Inhalation; Animals; Drug Synergism; Hot Temperature; Isoflurane

2007
Strychnine-sensitive glycine receptors mediate the analgesic but not hypnotic effects of emulsified volatile anesthetics.
    Pharmacology, 2007, Volume: 80, Issue:2-3

    Topics: Analgesia; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Emulsions; Enflurane;

2007
Isoflurane depression of spinal nociceptive processing and minimum alveolar anesthetic concentration are not attenuated in mice expressing isoflurane resistant gamma-aminobutyric acid type-A receptors.
    Neuroscience letters, 2007, Jun-15, Volume: 420, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Drug Resis

2007
Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:11

    Topics: Acetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Anesthetics, Inha

2007
Neurons in the ventral spinal cord are more depressed by isoflurane, halothane, and propofol than are neurons in the dorsal spinal cord.
    Anesthesia and analgesia, 2007, Volume: 105, Issue:4

    Topics: Action Potentials; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Animal

2007
Concentration-effect relations, prediction probabilities (Pk), and signal-to-noise ratios of different electroencephalographic parameters during administration of desflurane, isoflurane, and sevoflurane in rats.
    Anesthesiology, 2008, Volume: 108, Issue:2

    Topics: Animals; Brain; Cross-Over Studies; Desflurane; Electric Stimulation; Electroencephalography; Isoflu

2008
Suppression of noxious-induced c-fos expression in the rat lumbar spinal cord by isoflurane alone or combined with fentanyl.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:4

    Topics: Analgesics; Anesthesia; Animals; Drug Therapy, Combination; Electric Stimulation; Fentanyl; Isoflura

2008
Compensating for a lack of skill. Response to Protocol Review scenario: poor methodology.
    Lab animal, 2008, Volume: 37, Issue:4

    Topics: Anesthesia; Anesthetics, Inhalation; Animal Care Committees; Animal Technicians; Animal Welfare; Ani

2008
Compensating for a lack of skill.
    Lab animal, 2008, Volume: 37, Issue:4

    Topics: Anesthesia; Anesthetics, Inhalation; Animal Care Committees; Animal Technicians; Animal Welfare; Ani

2008
Compensating for a lack of skill. Response to Protocol Review scenario: try more training first.
    Lab animal, 2008, Volume: 37, Issue:4

    Topics: Anesthesia; Anesthetics, Inhalation; Animal Care Committees; Animal Technicians; Animal Welfare; Ani

2008
Compensating for a lack of skill. Response to Protocol Review scenario: not at our institute!
    Lab animal, 2008, Volume: 37, Issue:4

    Topics: Anesthesia; Anesthetics, Inhalation; Animal Care Committees; Animal Technicians; Animal Welfare; Ani

2008
Cardiovascular responses to noxious stimuli during isoflurane anesthesia are minimally affected by anesthetic action in the brain.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Brain; Goats; Heart Rate; Isoflurane; Pain

1995
Potency (minimum alveolar anesthetic concentration) of isoflurane is independent of peripheral anesthetic effects.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:1

    Topics: Anesthesia, Inhalation; Animals; Aorta; Axons; Blood Circulation; Catheterization; Dogs; Hindlimb; I

1995
The stereospecific effects of isoflurane isomers in vivo.
    European journal of pharmacology, 1994, Sep-22, Volume: 263, Issue:1-2

    Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Animals; Blood Pressure; Dose-Response Relations

1994
Does the brain influence somatic responses to noxious stimuli during isoflurane anesthesia?
    Anesthesiology, 1994, Volume: 81, Issue:6

    Topics: Anesthesia; Animals; Blood Gas Analysis; Blood Glucose; Brain; Dose-Response Relationship, Drug; Goa

1994
Systemic opioids do not suppress spinal sensitization after subcutaneous formalin in rats.
    Anesthesiology, 1994, Volume: 80, Issue:5

    Topics: Alfentanil; Animals; Drug Administration Schedule; Formaldehyde; Hot Temperature; Hyperalgesia; Inje

1994
Intrathecal midazolam reduces isoflurane MAC and increases the apnoeic threshold in rats.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:2

    Topics: Anesthesia, Spinal; Animals; Apnea; Blood Pressure; Carbon Dioxide; Dose-Response Relationship, Drug

1994
Anesthetic depth defined using multiple noxious stimuli during isoflurane/oxygen anesthesia. I. Motor reactions.
    Anesthesiology, 1994, Volume: 80, Issue:2

    Topics: Adult; Anesthesia, Inhalation; Anesthesiology; Female; Humans; Isoflurane; Male; Middle Aged; Motor

1994
Anesthetic depth defined using multiple noxious stimuli during isoflurane/oxygen anesthesia. II. Hemodynamic responses.
    Anesthesiology, 1994, Volume: 80, Issue:2

    Topics: Adult; Anesthesia, Inhalation; Anesthesiology; Blood Pressure; Female; Heart Rate; Hemodynamics; Hum

1994
Alterations in pain threshold and psychomotor response associated with subanaesthetic concentrations of inhalation anaesthetics in humans.
    British journal of anaesthesia, 1993, Volume: 70, Issue:6

    Topics: Adult; Anesthesia, Inhalation; Anesthetics; Enflurane; Ethers; Halothane; Humans; Isoflurane; Male;

1993
The relationship among brain, spinal cord and anesthetic requirements.
    Medical hypotheses, 1997, Volume: 48, Issue:1

    Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Brain; Electromyography; Goats; Humans; Isofl

1997
Intrathecal neurokinin-1 receptor antagonist reduces isoflurane MAC in rats.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:5 Pt 1

    Topics: Anesthetics, Inhalation; Animals; Biphenyl Compounds; Excitatory Amino Acid Antagonists; Isoflurane;

1997
Desflurane and nitrous oxide, but not nonimmobilizers, affect nociceptive responses.
    Anesthesia and analgesia, 1998, Volume: 86, Issue:3

    Topics: Animals; Chlorofluorocarbons; Cyclobutanes; Desflurane; Dose-Response Relationship, Drug; Fluorocarb

1998
Oleamide potentiates benzodiazepine-sensitive gamma-aminobutyric acid receptor activity but does not alter minimum alveolar anesthetic concentration.
    Anesthesia and analgesia, 1998, Volume: 86, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Benzodiazepines; Cerebrosides; Chloride Channels; Desflurane; Drug

1998
The effect of combined epidural and light general anesthesia on stress hormones in open heart surgery patients.
    Surgery today, 1998, Volume: 28, Issue:7

    Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; be

1998
The effect of combined epidural and light general anesthesia on stress hormones in open heart surgery patients.
    Surgery today, 1998, Volume: 28, Issue:7

    Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; be

1998
The effect of combined epidural and light general anesthesia on stress hormones in open heart surgery patients.
    Surgery today, 1998, Volume: 28, Issue:7

    Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; be

1998
The effect of combined epidural and light general anesthesia on stress hormones in open heart surgery patients.
    Surgery today, 1998, Volume: 28, Issue:7

    Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; be

1998
Intrathecal co-administration of NMDA antagonist and NK-1 antagonist reduces MAC of isoflurane in rats.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:7

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Anesthetics, Inhalation; Animals; Biphenyl Compounds;

1999
Isoflurane blunts electroencephalographic and thalamic-reticular formation responses to noxious stimulation in goats.
    Anesthesiology, 1999, Volume: 91, Issue:6

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Cerebral Cortex; Cortical Synchronization;

1999
Influence of low-dose anaesthetic agents on ventilatory control: where do we stand?
    British journal of anaesthesia, 1999, Volume: 83, Issue:2

    Topics: Anesthetics, Inhalation; Arousal; Depression, Chemical; Humans; Isoflurane; Methyl Ethers; Pain; Res

1999
Isoflurane action in the spinal cord blunts electroencephalographic and thalamic-reticular formation responses to noxious stimulation in goats.
    Anesthesiology, 2000, Volume: 92, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Blood Glucose; Electric Stimulation; Electrode

2000
Propofol directly depresses lumbar dorsal horn neuronal responses to noxious stimulation in goats.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2000, Volume: 47, Issue:3

    Topics: Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Brain; Central Ner

2000
P2-purinergic receptor antagonists reduce the minimum alveolar concentration of inhaled volatile anesthetics.
    Brain research, 2000, May-02, Volume: 864, Issue:1

    Topics: Adenosine Triphosphate; Anesthesia; Anesthetics, Inhalation; Animals; Antineoplastic Agents; Brain;

2000
Isoflurane anaesthetic depth in goats monitored using the bispectral index of the electroencephalogram.
    Veterinary research communications, 2000, Volume: 24, Issue:6

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Electroencephalography; Female; Goats; Intubation, Int

2000
Isoflurane depresses electroencephalographic and medial thalamic responses to noxious stimulation via an indirect spinal action.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Depression, Chemical; Electroencephalography; Evoked Potentials; F

2000
Acetylcholine receptors do not mediate the immobilization produced by inhaled anesthetics.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Atropine; Cholinergic Antagonists; Injections, Intraperitoneal; In

2002
Assessment of the analgesic effects of ketoprofen in ducks anesthetized with isoflurane.
    American journal of veterinary research, 2002, Volume: 63, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Ducks

2002
No correlation between quantitative electroencephalographic measurements and movement response to noxious stimuli during isoflurane anesthesia in rats.
    Anesthesiology, 1992, Volume: 77, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Electrocardiography; Female; Isoflurane; Male; Movement; Pain; Rats

1992
The effect of neuromuscular blockade with vecuronium on hemodynamic responses to noxious stimuli in the rat.
    Anesthesiology, 1989, Volume: 71, Issue:2

    Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Halothane; Heart Rate; Hemodynamics; Isoflurane; Ma

1989
Anaesthetic technique and pain in the newborn.
    Intensive care medicine, 1989, Volume: 15 Suppl 1

    Topics: Anesthesia; Fentanyl; Humans; Immune Tolerance; Infant, Newborn; Isoflurane; Pain

1989