Page last updated: 2024-10-29

isoflurane and Absence Seizure

isoflurane has been researched along with Absence Seizure in 39 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Research Excerpts

ExcerptRelevanceReference
"We aimed to determine the association between seizure termination and side effects of isoflurane for the treatment of refractory status epilepticus (RSE) and super-refractory status epilepticus (SRSE) in neurointensive care units (neuro-ICUs)."8.02Isoflurane in (Super-) Refractory Status Epilepticus: A Multicenter Evaluation. ( Bösel, J; Dimitriadis, K; Fink, GR; Fuchs, K; Fuhrer, H; Gerner, ST; Huttner, HB; Lehmann, F; Luger, S; Malter, MP; Müller, M; Neumann, B; Nichtweiß, J; Schaal, A; Scheibe, F; Schönenberger, S; Stetefeld, HR, 2021)
"We report a patient with acute encephalitis with refractory, repetitive partial seizures requiring a high concentration of isoflurane to suppress the seizures and showing rare abnormal findings in the bilateral thalamus on MRI during the convalescent period."7.76[A case of acute encephalitis with refractory, repetitive partial seizures requiring a high concentration of isoflurane to suppress the seizures and showing abnormal findings in the bilateral thalamus on MRI during the convalescent period]. ( Shiraga, H, 2010)
" The purpose of this study was to investigate the effects of sevoflurane and isoflurane on bupivacaine-induced arrhythmias and seizures in rats."7.69Sevoflurane is equivalent to isoflurane for attenuating bupivacaine-induced arrhythmias and seizures in rats. ( Fukuda, H; Hirabayashi, Y; Mitsuhata, H; Saitoh, K; Shimizu, R, 1996)
"The capacity of isoflurane to control seizures was assessed by electroencephalographic monitoring."7.01[Use of isoflurane as treatment for super-refractory status epilepticus]. ( Blázquez-Alcaide, V; Bodí, M; Daniel, X; Gil-Castillejos, D; Plans-Galván, O; Rosich, S, 2023)
"This is the first report of apparent seizure-like activity during anesthesia with propofol of an otherwise relatively healthy adult, in which concurrent EEG recording demonstrates the nonepileptic nature."5.42Electroencephalography of Seizure-Like Movements During General Anesthesia with Propofol: Seizures or Nonepileptic Events? ( Cornes, S; Flood, P; Li, Y, 2015)
"Using ion-selective microelectrodes, this study assessed isoflurane-induced extracellular ion dynamics in cortical slices of male and female Wistar rats in the absence of synaptic activity, in the presence of two-pore-domain potassium channel antagonists, during seizures, and during spreading depolarizations."4.31Deep Isoflurane Anesthesia Is Associated with Alterations in Ion Homeostasis and Specific Na+/K+-ATPase Impairment in the Rat Brain. ( Berndt, N; Dreier, JP; Friedman, A; Gonzalez Lopez, A; Grote Lambers, M; Kovács, R; Liotta, A; Maechler, M; Reiffurth, C; Schoknecht, K; Spies, C, 2023)
"We aimed to determine the association between seizure termination and side effects of isoflurane for the treatment of refractory status epilepticus (RSE) and super-refractory status epilepticus (SRSE) in neurointensive care units (neuro-ICUs)."4.02Isoflurane in (Super-) Refractory Status Epilepticus: A Multicenter Evaluation. ( Bösel, J; Dimitriadis, K; Fink, GR; Fuchs, K; Fuhrer, H; Gerner, ST; Huttner, HB; Lehmann, F; Luger, S; Malter, MP; Müller, M; Neumann, B; Nichtweiß, J; Schaal, A; Scheibe, F; Schönenberger, S; Stetefeld, HR, 2021)
" In experiment 2, both emulsified isoflurane and midazolam significantly suppressed lidocaine-induced tonic-clonic seizures."3.80Emulsified isoflurane increases convulsive thresholds of lidocaine and produces neural protection after convulsion in rats. ( Chen, X; Huang, H; Liu, J; Wang, X; Zhang, W; Zhou, C, 2014)
"We report a patient with acute encephalitis with refractory, repetitive partial seizures requiring a high concentration of isoflurane to suppress the seizures and showing rare abnormal findings in the bilateral thalamus on MRI during the convalescent period."3.76[A case of acute encephalitis with refractory, repetitive partial seizures requiring a high concentration of isoflurane to suppress the seizures and showing abnormal findings in the bilateral thalamus on MRI during the convalescent period]. ( Shiraga, H, 2010)
" We compared EEG data before and after clamping of the carotid artery for 2 different anesthesia protocols (isoflurane or propofol) in patients with and without development of cerebral ischemia, making use of SL analysis."3.75Detection of ischemic electroencephalography changes during carotid endarterectomy using synchronization likelihood analysis. ( Ferrier, C; Kesecioglu, J; Laman, M; Rijsdijk, M; Slooter, A; Stam, K, 2009)
" The purpose of this study was to investigate the effects of sevoflurane and isoflurane on bupivacaine-induced arrhythmias and seizures in rats."3.69Sevoflurane is equivalent to isoflurane for attenuating bupivacaine-induced arrhythmias and seizures in rats. ( Fukuda, H; Hirabayashi, Y; Mitsuhata, H; Saitoh, K; Shimizu, R, 1996)
"The capacity of isoflurane to control seizures was assessed by electroencephalographic monitoring."3.01[Use of isoflurane as treatment for super-refractory status epilepticus]. ( Blázquez-Alcaide, V; Bodí, M; Daniel, X; Gil-Castillejos, D; Plans-Galván, O; Rosich, S, 2023)
"The incidence of postoperative convulsive seizure was compared retrospectively during either isoflurane or sevoflurane anesthesia in patients after craniotomy."2.68[Convulsive seizure after craniotomy--comparison of isoflurane anesthesia and sevoflurane anesthesia]. ( Asahi, N; Hashimoto, K; Ohishi, S; Okuda, C; Sakio, H; Tanaka, Y, 1995)
"PGES following generalized seizures induced by electroconvulsive therapy (ECT) has been previously linked to antidepressant response."1.72Quiescence during burst suppression and postictal generalized EEG suppression are distinct patterns of activity. ( Avidan, MS; Brian Hickman, L; Ching, S; Farber, NB; Guay, CS; Hogan, RE; Huels, ER; Kafashan, M; Kelz, MB; Labonte, AK; Mashour, GA; Maybrier, H; Palanca, BJA; Subramanian, S, 2022)
"We find that the seizure focus elicits a rapid alteration in triggering, initiation, and propagation of burst suppression events."1.51Burst suppression uncovers rapid widespread alterations in network excitability caused by an acute seizure focus. ( Baird-Daniel, E; Daniel, A; Liou, JY; Ma, H; Schevon, CA; Schwartz, TH; Zhao, M, 2019)
"This is the first report of apparent seizure-like activity during anesthesia with propofol of an otherwise relatively healthy adult, in which concurrent EEG recording demonstrates the nonepileptic nature."1.42Electroencephalography of Seizure-Like Movements During General Anesthesia with Propofol: Seizures or Nonepileptic Events? ( Cornes, S; Flood, P; Li, Y, 2015)
"Seizure outcome was graded: I (seizure free without medication), II (seizure free with medication), III (> 50% seizure reduction) or IV (< 50% seizure reduction)."1.35Anesthesia and electrocorticography for epilepsy surgery: a Jordanian experience. ( Al-Ghanem, SS; Al-Oweidi, AS; Al-Qudah, AA; Tamimi, AF, 2009)
"Bupivacaine was infused at a constant rate while the pigs' ECGs and EEGs were recorded."1.28Bupivacaine toxicity in young pigs is age-dependent and is affected by volatile anesthetics. ( Badgwell, JM; Heavner, JE; Kytta, J, 1990)
"Flurothyl (CF3CH2OCH2CF3) produced convulsions in 50% of mice at 0."1.26Are convulsant gases also anesthetics? ( Collins, P; Eger, EI; Johnson, BH; Koblin, DD; Speers, L; Terrell, RC, 1981)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199011 (28.21)18.7374
1990's9 (23.08)18.2507
2000's7 (17.95)29.6817
2010's7 (17.95)24.3611
2020's5 (12.82)2.80

Authors

AuthorsStudies
Kafashan, M1
Brian Hickman, L1
Labonte, AK1
Huels, ER1
Maybrier, H1
Guay, CS1
Subramanian, S1
Farber, NB1
Ching, S1
Hogan, RE1
Kelz, MB1
Avidan, MS1
Mashour, GA1
Palanca, BJA1
Reiffurth, C1
Berndt, N1
Gonzalez Lopez, A1
Schoknecht, K1
Kovács, R1
Maechler, M1
Grote Lambers, M1
Dreier, JP1
Friedman, A1
Spies, C1
Liotta, A1
Plans-Galván, O1
Daniel, X1
Rosich, S1
Blázquez-Alcaide, V1
Gil-Castillejos, D1
Bodí, M1
Liou, JY1
Baird-Daniel, E1
Zhao, M1
Daniel, A1
Schevon, CA1
Ma, H1
Schwartz, TH1
Wilkinson, CM1
Kalisvaart, ACJ1
Kung, TFC1
Maisey, DR1
Klahr, AC1
Dickson, CT1
Colbourne, F1
Stetefeld, HR1
Schaal, A1
Scheibe, F1
Nichtweiß, J1
Lehmann, F1
Müller, M1
Gerner, ST1
Huttner, HB1
Luger, S1
Fuhrer, H1
Bösel, J1
Schönenberger, S1
Dimitriadis, K1
Neumann, B1
Fuchs, K1
Fink, GR1
Malter, MP1
Shiraga, H1
Zhou, C1
Huang, H1
Liu, J1
Wang, X1
Chen, X1
Zhang, W1
Li, Y1
Flood, P1
Cornes, S1
Isaeva, EV1
Al-Ghanem, SS1
Al-Oweidi, AS1
Tamimi, AF1
Al-Qudah, AA1
Rijsdijk, M1
Ferrier, C1
Laman, M1
Kesecioglu, J1
Stam, K1
Slooter, A1
Voss, LJ1
Melin, S1
Jacobson, G1
Sleigh, JW2
Baidya, DK1
Trikha, A1
Menon, S1
Garg, R1
Lecker, I1
Wang, DS1
Romaschin, AD1
Peterson, M1
Mazer, CD1
Orser, BA1
Perouansky, M1
Pearce, RA1
Kopjas, NN1
Jones, RT1
Bany, B1
Patrylo, PR1
Elsen, FP1
Liljelund, P1
Werner, DF1
Olsen, RW1
Homanics, GE1
Harrison, NL1
Wilson, MT1
Steyn-Ross, DA1
Steyn-Ross, ML1
Poulton, TJ1
Ellingson, RJ1
Koblin, DD1
Eger, EI4
Johnson, BH1
Collins, P1
Terrell, RC2
Speers, L1
Hashimoto, K1
Tanaka, Y1
Asahi, N1
Ohishi, S1
Sakio, H1
Okuda, C1
Fukuda, H1
Hirabayashi, Y1
Shimizu, R1
Saitoh, K1
Mitsuhata, H1
Antognini, JF1
Hirose, T1
Inoue, M1
Uchida, M1
Shingu, K2
Inagaki, C1
Gong, D1
Fang, Z1
Ionescu, P1
Laster, MJ1
Rubio González, MV1
Uña Orejón, S1
Cortiñas Sáenz, M1
Peyró García, RS1
Cuesta Tobarra, J1
Smith, RA1
Winter, PM1
Smith, M1
Ogawa, T1
Shibata, M1
Osawa, M1
Mori, K1
Scheller, MS1
Nakakimura, K1
Fleischer, JE1
Zornow, MH1
Badgwell, JM1
Heavner, JE1
Kytta, J1
Ong, RO1
Rosenberg, H1
Christys, AR1
Moss, E1
Powell, D1
Frost, EA2
Komatsu, H1
Ogli, K1
Hymes, JA1
Keats, AS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Correlating Electroconvulsive Therapy Response to Electroencephalographic Ictal Complexes and Postictal Markers[NCT04451135]31 participants (Actual)Interventional2020-10-09Active, not recruiting
Multicenter Retrospective Study of Isoflurane in Refractory and Super-Refractory Status Epilepticus (I-Seizure)[NCT05830864]120 participants (Anticipated)Observational [Patient Registry]2023-05-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for isoflurane and Absence Seizure

ArticleYear
[Use of isoflurane as treatment for super-refractory status epilepticus].
    Revista de neurologia, 2023, 05-01, Volume: 76, Issue:9

    Topics: Compassionate Use Trials; Humans; Intensive Care Units; Isoflurane; Retrospective Studies; Seizures;

2023

Trials

1 trial available for isoflurane and Absence Seizure

ArticleYear
[Convulsive seizure after craniotomy--comparison of isoflurane anesthesia and sevoflurane anesthesia].
    Masui. The Japanese journal of anesthesiology, 1995, Volume: 44, Issue:8

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Craniotomy; Ethers; Female; Humans; Is

1995

Other Studies

37 other studies available for isoflurane and Absence Seizure

ArticleYear
Quiescence during burst suppression and postictal generalized EEG suppression are distinct patterns of activity.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2022, Volume: 142

    Topics: Adult; Algorithms; Electroconvulsive Therapy; Electroencephalography; Humans; Isoflurane; Seizures

2022
Deep Isoflurane Anesthesia Is Associated with Alterations in Ion Homeostasis and Specific Na+/K+-ATPase Impairment in the Rat Brain.
    Anesthesiology, 2023, 06-01, Volume: 138, Issue:6

    Topics: Adenosine Triphosphatases; Animals; Brain; Female; Homeostasis; Isoflurane; Male; Potassium; Rats; R

2023
Burst suppression uncovers rapid widespread alterations in network excitability caused by an acute seizure focus.
    Brain : a journal of neurology, 2019, 10-01, Volume: 142, Issue:10

    Topics: 4-Aminopyridine; Animals; Brain; Disease Models, Animal; Electroencephalography; Isoflurane; Male; N

2019
The collagenase model of intracerebral hemorrhage in awake, freely moving animals: The effects of isoflurane.
    Brain research, 2020, 02-01, Volume: 1728

    Topics: Animals; Blood Glucose; Cerebral Hemorrhage; Collagenases; Disease Models, Animal; Electroencephalog

2020
Isoflurane in (Super-) Refractory Status Epilepticus: A Multicenter Evaluation.
    Neurocritical care, 2021, Volume: 35, Issue:3

    Topics: Anticonvulsants; Electroencephalography; Humans; Isoflurane; Retrospective Studies; Seizures; Status

2021
[A case of acute encephalitis with refractory, repetitive partial seizures requiring a high concentration of isoflurane to suppress the seizures and showing abnormal findings in the bilateral thalamus on MRI during the convalescent period].
    No to hattatsu = Brain and development, 2010, Volume: 42, Issue:1

    Topics: Acute Disease; Anticonvulsants; Child, Preschool; Encephalitis; Humans; Isoflurane; Magnetic Resonan

2010
Emulsified isoflurane increases convulsive thresholds of lidocaine and produces neural protection after convulsion in rats.
    Anesthesia and analgesia, 2014, Volume: 118, Issue:2

    Topics: Anesthesia, Conduction; Anesthetics, Inhalation; Anesthetics, Local; Animals; Cognition; Dose-Respon

2014
Electroencephalography of Seizure-Like Movements During General Anesthesia with Propofol: Seizures or Nonepileptic Events?
    A & A case reports, 2015, Dec-01, Volume: 5, Issue:11

    Topics: Anesthesia, General; Anesthetics, Intravenous; Desflurane; Elective Surgical Procedures; Electroence

2015
Effects of isoflurane on hippocampal seizures at immature rats in vivo.
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2008, Volume: 54, Issue:5

    Topics: Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Anticonvulsants; Disease Models, An

2008
Anesthesia and electrocorticography for epilepsy surgery: a Jordanian experience.
    Middle East journal of anaesthesiology, 2009, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Anesthesia, General; Anesthetics; Child; Craniotomy; Electroencephalography; Epil

2009
Detection of ischemic electroencephalography changes during carotid endarterectomy using synchronization likelihood analysis.
    Journal of neurosurgical anesthesiology, 2009, Volume: 21, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Anesthesia, General; Anesthetics, Inhalation; Anesthetic

2009
Role of Cx36 gap junction modulation in general anaesthetic anticonvulsant action.
    European journal of pharmacology, 2010, Sep-15, Volume: 643, Issue:1

    Topics: Anesthetics, General; Animals; Anticonvulsants; Connexins; Etomidate; Female; Gap Junction delta-2 P

2010
Anaesthetic management of emergency caesarean section in a patient with seizures and likely raised intracranial pressure due to tuberculous meningitis.
    Anaesthesia and intensive care, 2011, Volume: 39, Issue:5

    Topics: Adult; Androstanols; Anesthesia, Obstetrical; Anesthetics, Inhalation; Anesthetics, Intravenous; Ant

2011
Tranexamic acid concentrations associated with human seizures inhibit glycine receptors.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aminocaproic Acid; Animals; Anticonvulsants; Aprotinin; Binding, Com

2012
Effects on synaptic inhibition in the hippocampus do not underlie the amnestic and convulsive properties of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane.
    Anesthesiology, 2004, Volume: 101, Issue:1

    Topics: Amnesia; Anesthetics, Inhalation; Animals; Chromatography, Gas; Cyclobutanes; Electrophysiology; Exc

2004
Reeler mutant mice exhibit seizures during recovery from isoflurane-induced anesthesia.
    Epilepsy research, 2006, Volume: 69, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Female;

2006
GABA(A)-R alpha1 subunit knockin mutation leads to abnormal EEG and anesthetic-induced seizure-like activity in mice.
    Brain research, 2006, Mar-17, Volume: 1078, Issue:1

    Topics: Anesthetics; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography

2006
General anesthetic-induced seizures can be explained by a mean-field model of cortical dynamics.
    Anesthesiology, 2006, Volume: 104, Issue:3

    Topics: Anesthetics, General; Animals; Cerebral Cortex; Enflurane; Humans; Isoflurane; Models, Neurological;

2006
Seizure associated with induction of anesthesia with isoflurane.
    Anesthesiology, 1984, Volume: 61, Issue:4

    Topics: Adult; Anesthesia; Electroencephalography; Humans; Isoflurane; Male; Methyl Ethers; Seizures

1984
Are convulsant gases also anesthetics?
    Anesthesia and analgesia, 1981, Volume: 60, Issue:7

    Topics: Anesthesia, Inhalation; Anesthetics; Animals; Convulsants; Dogs; Female; Flurothyl; Isoflurane; Male

1981
Sevoflurane is equivalent to isoflurane for attenuating bupivacaine-induced arrhythmias and seizures in rats.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:3

    Topics: Anesthetics, Inhalation; Anesthetics, Local; Animals; Arrhythmias, Cardiac; Blood Pressure; Bupivaca

1996
Movement associated with high cerebral concentrations of isoflurane: no evidence of seizure activity.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Brain; Electroencephalography; Female; Goats; Isoflurane; Motor Ac

1996
[Involvement of enhanced glutamate release in halogenated volatile anesthetic-induced excitation in mouse brain].
    Masui. The Japanese journal of anesthesiology, 1997, Volume: 46, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Cerebral Cortex; Chlorofluorocarbons; Enflurane; Ethers; Glutamic

1997
Rat strain minimally influences anesthetic and convulsant requirements of inhaled compounds in rats.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:4

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Desflurane; Ethyl Ethers; Isoflurane; Nitrous Oxide; R

1998
[Convulsions after balanced general anesthesia in a newborn infant].
    Revista espanola de anestesiologia y reanimacion, 1999, Volume: 46, Issue:3

    Topics: Anesthesia, General; Anesthetics, General; Apnea; Bradycardia; Epilepsy, Generalized; Epilepsy, Toni

1999
Tolerance to and dependence on inhalational anesthetics.
    Anesthesiology, 1979, Volume: 50, Issue:6

    Topics: Anesthesia, Inhalation; Anesthetics; Animals; Cyclopropanes; Drug Tolerance; Humans; Isoflurane; Mic

1979
The divergent actions of volatile anaesthetics on background neuronal activity and reactive capability in the central nervous system in cats.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:8

    Topics: Amygdala; Animals; Brain; Cats; Electric Stimulation; Electroencephalography; Enflurane; Evoked Pote

1992
Cerebral effects of sevoflurane in the dog: comparison with isoflurane and enflurane.
    British journal of anaesthesia, 1990, Volume: 65, Issue:3

    Topics: Acoustic Stimulation; Anesthetics; Animals; Brain; Cerebrovascular Circulation; Dogs; Dose-Response

1990
Bupivacaine toxicity in young pigs is age-dependent and is affected by volatile anesthetics.
    Anesthesiology, 1990, Volume: 73, Issue:2

    Topics: Aging; Animals; Arrhythmias, Cardiac; Blood Pressure; Bupivacaine; Cardiac Output; Drug Interactions

1990
Malignant hyperthermia-like syndrome associated with metrizamide myelography.
    Anesthesia and analgesia, 1989, Volume: 68, Issue:6

    Topics: Adult; Diagnosis, Differential; Humans; Injections, Spinal; Isoflurane; Male; Malignant Hyperthermia

1989
Retrospective study of early postoperative convulsions after intracranial surgery with isoflurane or enflurane anaesthesia.
    British journal of anaesthesia, 1989, Volume: 62, Issue:6

    Topics: Anesthesia, Inhalation; Brain; Enflurane; Humans; Isoflurane; Postoperative Complications; Respirati

1989
Seizures after anesthesia: identifying the causes.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:10

    Topics: Anesthesia; Animals; Humans; Isoflurane; Nitrous Oxide; Seizures

1987
Opisthotonus during exposure to isoflurane, enflurane, and halothane in mice.
    Anesthesiology, 1987, Volume: 67, Issue:5

    Topics: Animals; Enflurane; Halothane; Isoflurane; Male; Mice; Mice, Inbred Strains; Seizures; Species Speci

1987
Seizures? Drugs? Timing?
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Anesthesia; Electroencephalography; Humans; Isoflurane; Methyl Ethers; Seizures; Time Factors

1986
Seizure activity during isoflurane anesthesia.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:3

    Topics: Adult; Anesthesia, General; Humans; Isoflurane; Male; Methyl Ethers; Seizures

1985
Are seizures caused by nitrous oxide or isoflurane?
    Anesthesiology, 1985, Volume: 62, Issue:5

    Topics: Humans; Isoflurane; Methyl Ethers; Nitrous Oxide; Seizures

1985
Seizures from isoflurane?
    Anesthesia and analgesia, 1985, Volume: 64, Issue:12

    Topics: Electroencephalography; Humans; Isoflurane; Methyl Ethers; Seizures

1985