isodesmosine has been researched along with Pulmonary Disease, Chronic Obstructive in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 23 (82.14) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Baut, DA; Tanaka, N; Usuki, T; Yokoo, R | 1 |
| Kim, C; Kim, SH; Kim, TH; Ko, Y; Lee, JH; Lee, JS; Lee, SD; Lim, SY; Oh, YM; Park, YB; Rhee, CK; Seo, JB; Yoo, HJ; Yoo, KH | 1 |
| Cantor, J; Ma, S; Turino, G | 1 |
| Cantor, JO; Lin, YY; Ma, S; Turino, GM | 2 |
| Turino, GM | 1 |
| Iadarola, P; Luisetti, M | 1 |
| Hayashi, T; Lin, YY; Ma, S; Turino, GM; Usuki, T; Yanuma, H | 1 |
| Bischoff, R; Hendriks, G; Hermans, J; Ongay, S; ten Hacken, NH; van de Merbel, NC; van den Berge, M | 1 |
| Komatsu, A; Koseki, Y; Sugimura, T; Usuki, T | 1 |
| Cantor, J; Liu, M; Liu, S; Liu, X; Ma, S; Turino, G | 1 |
| Komatsu, A; Tanigawa, T; Usuki, T | 1 |
| Bolton, CE; Huang, JT; MacNee, W; Miller, BE; Palmer, CN; Rabinovich, RA; Tal-Singer, R; Thomson, NC | 1 |
| Casado, B; Iadarola, P; Lin, YY; Luisetti, M; Ma, S; Snider, GL; Stone, PJ; Turino, GM; Viglio, S | 1 |
| Lin, YY; Ma, S; Tartell, L; Turino, GM | 1 |
| Cantor, JO; Cerreta, JM; Liu, M; Ma, S; Ochoa, M; Turino, GM | 1 |
| He, J; Lin, YY; Ma, S; Robbins, RA; Slowik, N; Soldin, OP; Turino, GM | 1 |
| Lin, YY; Ma, S; Turino, GM | 2 |
| Cantor, JO; Lin, YY; Luisetti, M; Ma, S; Turino, GM | 1 |
| Anderson, M; de Verdier, MG; Engström, G; Forsman-Semb, K; Lindberg, CA; Nihlén, U; Svartengren, M | 1 |
| Cook, J; Creaser, CS; Devenport, NA; Parkash, V; Reynolds, JC; Weston, DJ | 1 |
| Iadarola, P; Luisetti, M; Stolk, J | 1 |
| Cantor, JO; He, J; Lin, YY; Ma, S; Turino, GM | 1 |
| Elmlinger, M; Ernst, P; Hohlfeld, JM; Holz, O; Krug, N; Lahu, G; Lauer, G; Müller, M; Rittinghausen, S; Röpcke, S | 1 |
| MacNee, W | 1 |
| Cutler, P; Döbeli, H; Friedlein, A; Lamerz, J; Soder, N | 1 |
| Lieberman, S; Lin, YY; Ma, S; Turino, GM | 1 |
5 review(s) available for isodesmosine and Pulmonary Disease, Chronic Obstructive
| Article | Year |
|---|---|
The role of desmosines as biomarkers for chronic obstructive pulmonary disease.
Topics: Animals; Biomarkers; Desmosine; Elastic Tissue; Humans; Isodesmosine; Lung; Predictive Value of Tests; Prognosis; Pulmonary Disease, Chronic Obstructive | 2013 |
Biomarkers in Alpha-1 Antitrypsin Deficiency Chronic Obstructive Pulmonary Disease.
Topics: alpha 1-Antitrypsin Deficiency; Biomarkers; Desmosine; Elastin; Fibrinogen; Humans; Isodesmosine; Leukocyte Elastase; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Uteroglobin | 2016 |
Matrix elastin: a promising biomarker for chronic obstructive pulmonary disease.
Topics: Biomarkers; Desmosine; Elastin; Humans; Isodesmosine; Lung; Peptide Hydrolases; Pulmonary Disease, Chronic Obstructive; Sputum | 2011 |
Elastin degradation: an effective biomarker in COPD.
Topics: Biomarkers; Bronchodilator Agents; Chromatography, High Pressure Liquid; Desmosine; Disease Progression; Drug Monitoring; Elastin; Humans; Isodesmosine; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Tandem Mass Spectrometry | 2012 |
Systemic inflammatory biomarkers and co-morbidities of chronic obstructive pulmonary disease.
Topics: Adiponectin; Aging; Airway Remodeling; Biomarkers; C-Reactive Protein; Cachexia; Cardiovascular Diseases; CD40 Ligand; Chemokines, CC; Cytokines; Desmosine; Fibrinogen; Humans; Inflammation; Intercellular Adhesion Molecule-1; Isodesmosine; Lung Neoplasms; Matrix Metalloproteinases; Natriuretic Peptide, Brain; Osteoprotegerin; Pulmonary Disease, Chronic Obstructive; Pulmonary Surfactant-Associated Protein D; Serum Amyloid A Protein; Severity of Illness Index; Telomere; Uteroglobin | 2013 |
2 trial(s) available for isodesmosine and Pulmonary Disease, Chronic Obstructive
| Article | Year |
|---|---|
A pilot clinical trial to determine the safety and efficacy of aerosolized hyaluronan as a treatment for COPD.
Topics: Administration, Inhalation; Adult; Aerosols; Aged; Arizona; Biomarkers; Desmosine; Double-Blind Method; Elastin; Humans; Hyaluronic Acid; Isodesmosine; Lung; Middle Aged; New York City; Pilot Projects; Pulmonary Disease, Chronic Obstructive; Sputum; Time Factors; Treatment Outcome | 2017 |
Determination of free desmosine in human plasma and its application in two experimental medicine studies.
Topics: Adult; Age Factors; Aged; Biomarkers; Body Mass Index; Body Weight; Case-Control Studies; Chemical Precipitation; Chromatography, High Pressure Liquid; Desmosine; Deuterium; Female; Humans; Isodesmosine; Male; Mass Spectrometry; Middle Aged; Pulmonary Disease, Chronic Obstructive; Reference Values; Reproducibility of Results; Russia; Smoking; United States | 2013 |
21 other study(ies) available for isodesmosine and Pulmonary Disease, Chronic Obstructive
| Article | Year |
|---|---|
Preparation of isodesmosine-KLH conjugate for ELISA system.
Topics: Biomarkers; Enzyme-Linked Immunosorbent Assay; Hemocyanins; Isodesmosine; Pulmonary Disease, Chronic Obstructive; Stereoisomerism | 2020 |
Urinary desmosine is associated with emphysema severity and frequent exacerbation in patients with COPD.
Topics: Aged; Biomarkers; Cohort Studies; Desmosine; Female; Humans; Isodesmosine; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Severity of Illness Index; Tomography, X-Ray Computed | 2018 |
The Therapeutic Potential of Hyaluronan in COPD.
Topics: Adjuvants, Immunologic; Animals; Biomarkers; Clinical Trials as Topic; Desmosine; Disease Models, Animal; Elastin; Glycosaminoglycans; Humans; Hyaluronic Acid; Immunity, Cellular; Isodesmosine; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Rats | 2018 |
Chronic Obstructive Pulmonary Disease. A Biomarker and a Potential Therapy.
Topics: alpha 1-Antitrypsin Deficiency; Animals; Biomarkers; Desmosine; Elastin; Humans; Isodesmosine; Leukocyte Elastase; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema | 2018 |
Stable deuterium internal standard for the isotope-dilution LC-MS/MS analysis of elastin degradation.
Topics: Biomarkers; Bronchoalveolar Lavage; Chromatography, Liquid; Desmosine; Deuterium; Elastin; Humans; Isodesmosine; Proteolysis; Pulmonary Disease, Chronic Obstructive; Reference Standards; Tandem Mass Spectrometry | 2013 |
Quantification of free and total desmosine and isodesmosine in human urine by liquid chromatography tandem mass spectrometry: a comparison of the surrogate-analyte and the surrogate-matrix approach for quantitation.
Topics: Aged; Biomarkers; Calibration; Case-Control Studies; Chromatography, Liquid; Desmosine; Female; Humans; Isodesmosine; Male; Middle Aged; Peptides; Pulmonary Disease, Chronic Obstructive; Tandem Mass Spectrometry | 2014 |
Biomimetic Chichibabin pyridine synthesis of the COPD biomarkers and elastin cross-linkers isodesmosine and desmosine.
Topics: Biomarkers; Biomimetics; Cross-Linking Reagents; Desmosine; Elastin; Humans; Isodesmosine; Lanthanoid Series Elements; Molecular Structure; Pulmonary Disease, Chronic Obstructive; Pyridines; Pyridinium Compounds | 2014 |
The Ratio of Free to Bound Desmosine and Isodesmosine May Reflect Emphysematous Changes in COPD.
Topics: Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Chromatography, Liquid; Desmosine; Disease Models, Animal; Female; Isodesmosine; Lung; Mesocricetus; Pancreatic Elastase; Predictive Value of Tests; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Severity of Illness Index; Tandem Mass Spectrometry | 2015 |
[(13)C3,(15)N1]-labeled isodesmosine: A potential internal standard for LC-MS/MS analysis of desmosines in elastin degradation.
Topics: Biomarkers; Carbon Isotopes; Chromatography, Liquid; Desmosine; Elastin; Isodesmosine; Molecular Structure; Nitrogen Isotopes; Pulmonary Disease, Chronic Obstructive; Tandem Mass Spectrometry | 2015 |
Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Desmosine; Elastin; Female; Forced Expiratory Volume; Humans; Isodesmosine; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Smoking; Time Factors | 2016 |
Desmosine as a biomarker of elastin degradation in COPD: current status and future directions.
Topics: Adult; alpha 1-Antitrypsin Deficiency; Child; Chromatography, Liquid; Desmosine; Elastin; Female; Humans; Isodesmosine; Male; Models, Biological; Peptides; Pulmonary Disease, Chronic Obstructive; Smoking; Tandem Mass Spectrometry | 2008 |
The effect of tiotropium therapy on markers of elastin degradation in COPD.
Topics: Bronchodilator Agents; Desmosine; Elastin; Forced Expiratory Volume; Humans; Isodesmosine; Pancreatic Elastase; Pulmonary Disease, Chronic Obstructive; Scopolamine Derivatives; Smoking Cessation; Tiotropium Bromide; Vital Capacity | 2009 |
Therapeutic effects of hyaluronan on smoke-induced elastic fiber injury: does delayed treatment affect efficacy?
Topics: Administration, Inhalation; Aerosols; Animals; Bronchoalveolar Lavage Fluid; Desmosine; Disease Models, Animal; Dose-Response Relationship, Drug; Elastic Tissue; Female; Hyaluronic Acid; Isodesmosine; Lung; Mice; Mice, Inbred DBA; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Smoking; Time Factors | 2011 |
The effect of secondhand smoke exposure on markers of elastin degradation.
Topics: Adult; Aged; Biomarkers; Cohort Studies; Cotinine; Desmosine; Elastin; Female; Humans; Isodesmosine; Male; Middle Aged; Nicotine; Pulmonary Disease, Chronic Obstructive; Risk Factors; Smoking; Tobacco Smoke Pollution; Young Adult | 2011 |
Quantitation of desmosine and isodesmosine in urine, plasma, and sputum by LC-MS/MS as biomarkers for elastin degradation.
Topics: Amino Acids; Biomarkers; Case-Control Studies; Chromatography, Liquid; Desmosine; Elastin; Humans; Hydrochloric Acid; Hydrolysis; Isodesmosine; Pulmonary Disease, Chronic Obstructive; Reproducibility of Results; Sensitivity and Specificity; Sputum; Tandem Mass Spectrometry | 2011 |
Total desmosines in plasma and urine correlate with lung function.
Topics: Aged; Aged, 80 and over; Biomarkers; Desmosine; Female; Humans; Isodesmosine; Lung; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Registries; Respiratory Function Tests; Sensitivity and Specificity; Smoking | 2012 |
Determination of free desmosine and isodesmosine as urinary biomarkers of lung disorder using ultra performance liquid chromatography-ion mobility-mass spectrometry.
Topics: Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Desmosine; Female; Humans; Isodesmosine; Limit of Detection; Linear Models; Male; Mass Spectrometry; Pulmonary Disease, Chronic Obstructive; Reproducibility of Results | 2011 |
Desmosine, a biomarker for COPD: old and in the way.
Topics: Desmosine; Female; Humans; Isodesmosine; Lung; Male; Pulmonary Disease, Chronic Obstructive | 2012 |
Repeatability of and relationship between potential COPD biomarkers in bronchoalveolar lavage, bronchial biopsies, serum, and induced sputum.
Topics: Adult; Aged; Analysis of Variance; Biomarkers; Biopsy; Bronchoalveolar Lavage Fluid; Bronchoscopy; C-Reactive Protein; Cytokines; Desmosine; Female; Humans; Interleukin-6; Isodesmosine; Lung; Male; Middle Aged; Neutrophils; Pulmonary Disease, Chronic Obstructive; Smoking; Sputum; Time Factors; von Willebrand Factor | 2012 |
The detection and quantitation of free desmosine and isodesmosine in human urine and their peptide-bound forms in sputum.
Topics: Adult; Aged; Biomarkers; Creatinine; Desmosine; Female; Humans; Isodesmosine; Male; Mass Spectrometry; Middle Aged; Pulmonary Disease, Chronic Obstructive; Sputum | 2003 |
Measurements of desmosine and isodesmosine by mass spectrometry in COPD.
Topics: Adult; Aged; Aged, 80 and over; alpha 1-Antitrypsin Deficiency; Desmosine; Elastin; Female; Humans; Isodesmosine; Male; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Prognosis; Pulmonary Disease, Chronic Obstructive; Sensitivity and Specificity; Sputum | 2007 |