isocoumarin-nm-3 and Arthritis

isocoumarin-nm-3 has been researched along with Arthritis* in 1 studies

Other Studies

1 other study(ies) available for isocoumarin-nm-3 and Arthritis

Article	Year
Synthesis and biological evaluation of cytogenin derivatives. The Journal of antibiotics, 2001, Volume: 54, Issue:3 To enhance the stability in vivo, new derivatives of cytogenin were synthesized, and their biological activity and stability in mice were estimated. 2-(8-Hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl)propionic acid (NM-3) was found to be the most stable among them. It modified collagen-induced arthritis in mice. It also showed potent anti-angiogenic activity in a mouse dorsal air sac assay. Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Arthritis; Coumarins; Drug Stability; In Vitro Techniques; Isocoumarins; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred DBA; Mice, Inbred ICR; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared	2001

Article

Year

Synthesis and biological evaluation of cytogenin derivatives.

The Journal of antibiotics, 2001, Volume: 54, Issue:3

To enhance the stability in vivo, new derivatives of cytogenin were synthesized, and their biological activity and stability in mice were estimated. 2-(8-Hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl)propionic acid (NM-3) was found to be the most stable among them. It modified collagen-induced arthritis in mice. It also showed potent anti-angiogenic activity in a mouse dorsal air sac assay.

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Arthritis; Coumarins; Drug Stability; In Vitro Techniques; Isocoumarins; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred DBA; Mice, Inbred ICR; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared

2001