isocitric acid has been researched along with Parkinson Disease in 1 studies
isocitric acid: RN given refers to unlabeled parent cpd
isocitric acid : A tricarboxylic acid that is propan-1-ol with a hydrogen at each of the 3 carbon positions replaced by a carboxy group.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, J | 1 |
| Kim, MJ | 1 |
| Yoon, W | 1 |
| Kim, EY | 1 |
| Kim, H | 1 |
| Lee, Y | 1 |
| Min, B | 1 |
| Kang, KS | 1 |
| Son, JH | 1 |
| Park, HT | 1 |
| Chung, J | 1 |
| Koh, H | 1 |
1 other study available for isocitric acid and Parkinson Disease
| Article | Year |
|---|---|
Isocitrate protects DJ-1 null dopaminergic cells from oxidative stress through NADP+-dependent isocitrate dehydrogenase (IDH).
Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Drosophila Proteins; | 2017 |