isocarboxazid has been researched along with Parkinson Disease in 3 studies
Isocarboxazid: An MAO inhibitor that is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in the treatment of panic disorder and the phobic disorders. (From AMA, Drug Evaluations Annual, 1994, p311)
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, AB | 1 |
| Pare, CM | 1 |
| Nicholson, WJ | 1 |
| Price, K | 1 |
| Stacey, RS | 1 |
| Figuerido, JA | 1 |
| De la Herrán, J | 1 |
| Dandiya, PC | 1 |
| Bhargava, LP | 1 |
1 trial available for isocarboxazid and Parkinson Disease
| Article | Year |
|---|---|
Brain amine concentrations after monoamine oxidase inhibitor administration.
Topics: Aged; Alkynes; Autopsy; Brain; Brain Stem; Caudate Nucleus; Chlorpromazine; Dopamine; Humans; Hypoth | 1972 |
2 other studies available for isocarboxazid and Parkinson Disease
| Article | Year |
|---|---|
[Personal experience in the treatment of Parkinson's disease with L-Dopa].
Topics: Adult; Aged; Dihydroxyphenylalanine; Drug Synergism; Female; Humans; Isocarboxazid; Male; Middle Age | 1970 |
The antiparkinsonian activity of monoamine oxidase inhibitors and other agents in rats and mice.
Topics: Animals; Dextroamphetamine; Diphenhydramine; Imipramine; Iproniazid; Isocarboxazid; Mice; Monoamine | 1968 |