Compounds > isobutyramide

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isobutyramide and beta-Thalassemia

isobutyramide has been researched along with beta-Thalassemia in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (60.00)	18.2507
2000's	2 (40.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dover, GJ; Faller, DV; Ginder, GD; Olivieri, NF; Perrine, SP; Vichinsky, EP	1
Daftari, P; Dover, GH; Faller, DV; Jin, Y; Mays, A; Perrine, SP; Walsh, CT	1
Bianchi, P; Cappellini, MD; Ciceri, L; Comino, A; Fiorelli, G; Graziadei, G; Pomati, M	1
Bianchi, P; Ciceri, L; Comino, A; Domenica Cappellini, M; Fiorelli, G; Graziadei, G; Porcella, A	1
Bührer, C; Henze, G; Kage, A; Kulozik, AE; Mesche, M; Müller, C; Ohlendorf, D; Reich, S; Sinha, P; Vetter, B	1

Trials

2 trial(s) available for isobutyramide and beta-Thalassemia

Article	Year
Butyrate trials. Annals of the New York Academy of Sciences, 1998, Jun-30, Volume: 850 Topics: Adult; Amides; beta-Thalassemia; Blood Transfusion; Erythropoietin; Female; Fetal Hemoglobin; Globins; Humans; Male; Receptors, Transferrin	1998
Oral isobutyramide therapy in patients with thalassemia intermedia: results of a phase II open study. Blood cells, molecules & diseases, 2000, Volume: 26, Issue:1 Topics: Administration, Oral; Adult; Amides; Analysis of Variance; Antineoplastic Agents; beta-Thalassemia; Cell Size; Drug Evaluation; Female; Fetal Hemoglobin; Genotype; Humans; Male; Pilot Projects; White People	2000

Other Studies

3 other study(ies) available for isobutyramide and beta-Thalassemia

Article	Year
Butyrate derivatives. New agents for stimulating fetal globin production in the beta-globin disorders. The American journal of pediatric hematology/oncology, 1994, Volume: 16, Issue:1 Topics: Adolescent; Adult; Amides; Anemia, Sickle Cell; Animals; Arginine; beta-Thalassemia; Butyrates; Child; Child, Preschool; Fetal Hemoglobin; Globins; Humans; Promoter Regions, Genetic	1994
Isobutyramide, an orally bioavailable butyrate analogue, stimulates fetal globin gene expression in vitro and in vivo. British journal of haematology, 1994, Volume: 88, Issue:3 Topics: Administration, Oral; Amides; Anemia, Sickle Cell; Animals; beta-Thalassemia; Erythroid Precursor Cells; Fetal Hemoglobin; Gene Expression Regulation; Genes, Reporter; Globins; Humans; Male; Papio; Promoter Regions, Genetic; Transfection	1994
Oral isobutyramide reduces transfusion requirements in some patients with homozygous beta-thalassemia. Blood, 2000, Nov-15, Volume: 96, Issue:10 Topics: Administration, Oral; Adolescent; Adult; Amides; Antineoplastic Agents; beta-Thalassemia; Blood; Blood Transfusion; Child; Child, Preschool; Drug Evaluation; Erythrocyte Indices; Erythropoietin; Female; Fetal Hemoglobin; Genotype; Hemoglobins; Hemolysis; Homozygote; Humans; Iron; Longitudinal Studies; Male; Patient Compliance; Time Factors	2000