isavuconazole has been researched along with Burns* in 1 studies
1 other study(ies) available for isavuconazole and Burns
Article | Year |
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Widespread Lichtheimia Infection in a Patient with Extensive Burns: Opportunities for Novel Antifungal Agents.
The Mucorales fungi-formerly classified as the zygomycetes-are environmentally ubiquitous fungi, but generally rare causes of clinical infections. In the immunocompromised host, however, they can cause invasive, rapidly spreading infections that confer a high risk of morbidity and mortality, often despite surgical and antifungal therapy. Patients with extensive burn injuries are particularly susceptible to skin and soft-tissue infections with these organisms. Here, we present a case of Lichtheimia infection in a patient with extensive full-thickness burns that required significant and repeated surgical debridement successfully treated with isavuconazole and adjunctive topical amphotericin B washes. We also review the available literature on contemporary antifungal treatment for Lichtheimia species and related Mucorales fungi. Topics: Amphotericin B; Antifungal Agents; Burns; Debridement; Dermatomycoses; Humans; Male; Middle Aged; Mucorales; Mucormycosis; Nitriles; Pyridines; Treatment Outcome; Triazoles | 2019 |