isatin has been researched along with Benign Neoplasms in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 10 (43.48) | 24.3611 |
| 2020's | 12 (52.17) | 2.80 |
| Authors | Studies |
|---|---|
| Colau, D; Dolusić, E; Frédérick, R; Larrieu, P; Masereel, B; Moineaux, L; Pilotte, L; Pochet, L; Stroobant, V; Van den Eynde, B; Wouters, J | 1 |
| Fan, ZC; Gao, ML; Han, KL; Liu, H; Sun, H; Teng, YO; Wang, J; Yu, P; Zhang, YM; Zhao, HY; Zhou, Y | 1 |
| Arredondo-Espinoza, EU; Avalos-Alanís, FG; Balderas-Renteria, I; Espinosa-Rodriguez, BA; Nieto-Moreno, AM | 1 |
| Alkahtani, S; Anwar, J; Arshad, N; Channar, PA; Farooqi, SI; Javaid, M; Javed, A; Mir, MI; Perveen, F; Saeed, A | 1 |
| Chen, M; Wang, R; Zhang, Q | 1 |
| Cao, W; Chen, X; Ding, F; Dong, T; Wang, P | 1 |
| Chen, L; Pan, B; Xu, D; Xu, Z | 1 |
| Alanazi, AS; Alanazi, MM; Alsaif, NA; Alsfouk, AA; Mirgany, TO | 1 |
| Alanazi, AS; Alanazi, MM | 1 |
| Hou, Y; Shang, C; Wang, H; Yun, J | 1 |
| Aboagye, EO; Årstad, E; Carroll, L; Diocou, S; Gendron, T; Glaser, M; Pedley, RB; Rajkumar, V; Sander, K; Sin, PKB; Witney, TH; Yan, R | 1 |
| Ding, Z; Zeng, C; Zhou, M | 1 |
| Ding, Y; Fu, Y; Hao, L; Teng, Y; Yu, P; Yuan, Y; Zhao, L | 1 |
| Bao, K; Cao, J; Chen, XB; He, QJ; Jiang, L; Sheng, R; Yang, B; Ying, MD; Zhu, H; Zhu, HY | 1 |
| Ghosh, S; Jha, A; Ramarao, TA; Samanta, PK; Satpati, P; Sen, A | 1 |
| Chou, CJ; Ding, Q; Gao, Q; Gao, S; Li, X; Liang, X; Xu, W; Zang, J; Zhang, Y | 1 |
| Abbas, SY; Ammar, YA; Belal, A; Mehany, ABM; Mohamed, YA; Ragab, A; Sh El-Sharief, AM | 1 |
| Gao, J; Lei, D; Li, X; Liang, C; Xia, J; Yao, Q | 1 |
| Chen, DL; Chu, W; Engle, JT; Griffin, EA; Mach, RH; Miller, JP; Zhou, D | 1 |
| Haufe, G; Limpachayaporn, P; Schäfers, M | 1 |
| Evdokimov, NM; Kornienko, A; Magedov, IV; McBrayer, D | 1 |
| Aboagye, EO; Arstad, E; Glaser, M; Nguyen, QD; Perumal, M; Shan, B; Smith, G | 1 |
| Aboagye, EO; Challapalli, A; Fortt, R; Nguyen, QD; Smith, G | 1 |
4 review(s) available for isatin and Benign Neoplasms
| Article | Year |
|---|---|
Isatin-azole hybrids and their anticancer activities.
Topics: Animals; Antineoplastic Agents; Azoles; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Isatin; Molecular Structure; Neoplasms; Structure-Activity Relationship | 2020 |
Recent advances in isatin hybrids as potential anticancer agents.
Topics: Animals; Antineoplastic Agents; Azoles; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Imines; Isatin; Molecular Structure; Neoplasms; Quinolines; Structure-Activity Relationship | 2020 |
Isatin sulfonamides: potent caspases-3 and -7 inhibitors, and promising PET and SPECT radiotracers for apoptosis imaging.
Topics: Animals; Apoptosis; Caspase 3; Caspase 7; Caspase Inhibitors; Humans; Isatin; Neoplasms; Positron-Emission Tomography; Protein Binding; Radiography; Structure-Activity Relationship; Sulfanilamide; Sulfanilamides; Tomography, Emission-Computed, Single-Photon | 2015 |
Imaging apoptosis with positron emission tomography: 'bench to bedside' development of the caspase-3/7 specific radiotracer [(18)F]ICMT-11.
Topics: Apoptosis; Azides; Caspase 3; Caspase 7; Diagnostic Imaging; Fluorine Radioisotopes; Humans; Indoles; Isatin; Models, Biological; Neoplasms; Point-of-Care Systems; Positron-Emission Tomography; Radioactive Tracers; Substrate Specificity; Sulfonamides; Translational Research, Biomedical | 2012 |
19 other study(ies) available for isatin and Benign Neoplasms
| Article | Year |
|---|---|
Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.
Topics: Animals; Antineoplastic Agents; Biological Availability; Cell Line; Drug Design; Enzyme Inhibitors; Humans; Immunologic Factors; Indoles; Kinetics; Mice; Neoplasms; Structure-Activity Relationship; Tryptophan Oxygenase | 2011 |
Synthesis and anti-cancer activity evaluation of 5-(2-carboxyethenyl)-isatin derivatives.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Isatin; Jurkat Cells; Leukemia, T-Cell; Membrane Potential, Mitochondrial; Mitochondria; Neoplasms | 2016 |
Comparative Anticancer Activity and Molecular Docking of Different Isatin-Based Scaffolds.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cyclin-Dependent Kinase 2; Humans; Isatin; Molecular Docking Simulation; Neoplasms; Schiff Bases; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |
Investigations on Anticancer Potentials by DNA Binding and Cytotoxicity Studies for Newly Synthesized and Characterized Imidazolidine and Thiazolidine-Based Isatin Derivatives.
Topics: Antineoplastic Agents; Cell Proliferation; DNA; HeLa Cells; Humans; Imidazolidines; Isatin; MCF-7 Cells; Molecular Structure; Neoplasms; Structure-Activity Relationship; Thiazolidines | 2022 |
Artemisinin-isatin hybrids tethered via ethylene linker and their anti-lung cancer activity.
Topics: Antineoplastic Agents; Artemisinins; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Ethylenes; Humans; Isatin; Molecular Structure; Neoplasms; Structure-Activity Relationship | 2023 |
The anti-breast cancer potential of dihydroartemisinin-isatin hybrids with hydrogen bond donors at C-3 position of isatin moiety.
Topics: Antineoplastic Agents; Hydrogen Bonding; Isatin; Molecular Structure; Neoplasms; Structure-Activity Relationship | 2023 |
Design, synthesis, and in vitro cytotoxicity evaluation of novel dihydroartemisinin-isatin hybrids tethered via different length of esters as potential anti-breast cancer agents.
Topics: Antineoplastic Agents; Artemisinins; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Humans; Isatin; Molecular Structure; Neoplasms; Structure-Activity Relationship | 2023 |
Antiproliferative Activity, Multikinase Inhibition, Apoptosis- Inducing Effects and Molecular Docking of Novel Isatin-Purine Hybrids.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Isatin; Molecular Docking Simulation; Neoplasms; Purines; Vascular Endothelial Growth Factor A | 2023 |
Novel 7-Deazapurine Incorporating Isatin Hybrid Compounds as Protein Kinase Inhibitors: Design, Synthesis, In Silico Studies, and Antiproliferative Evaluation.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Isatin; Molecular Structure; Neoplasms; Protein Kinase Inhibitors; Structure-Activity Relationship | 2023 |
One-Pot Radiosynthesis and Biological Evaluation of a Caspase-3 Selective 5-[
Topics: Animals; Apoptosis; Caspase 3; Cell Line, Tumor; Copper; Fluorine Radioisotopes; Heterografts; Humans; Iodine Radioisotopes; Isatin; Mice; Neoplasms; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Triazoles | 2019 |
Synthesis and Antiproliferatory Activities Evaluation of Multi-Substituted Isatin Derivatives.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Drug Design; Hep G2 Cells; HT29 Cells; Human Umbilical Vein Endothelial Cells; Humans; Isatin; K562 Cells; Molecular Structure; Neoplasms; Structure-Activity Relationship | 2020 |
Bis-isatin derivatives: design, synthesis, and biological activity evaluation as potent dimeric DJ-1 inhibitors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Design; Enzyme Inhibitors; Female; Ferroptosis; Humans; Isatin; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Protein Deglycase DJ-1; Protein Structure, Quaternary; Xenograft Model Antitumor Assays | 2021 |
Triazole based isatin derivatives as potential inhibitor of key cancer promoting kinases- insight from electronic structure, docking and molecular dynamics simulations.
Topics: Electronics; Humans; Isatin; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Neoplasms; Protein Binding; Protein Kinase Inhibitors; Triazoles | 2021 |
Design, synthesis and anti-tumor activity study of novel histone deacetylase inhibitors containing isatin-based caps and o-phenylenediamine-based zinc binding groups.
Topics: Cell Line, Tumor; Cell Proliferation; Drug Design; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Humans; Isatin; Molecular Docking Simulation; Neoplasms; Phenylenediamines; Zinc | 2017 |
Design, synthesis, antiproliferative activity, molecular docking and cell cycle analysis of some novel (morpholinosulfonyl) isatins with potential EGFR inhibitory activity.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Isatin; Molecular Docking Simulation; Neoplasms; Protein Kinase Inhibitors | 2018 |
Synthesis, in vitro and in vivo antitumor activity of symmetrical bis-Schiff base derivatives of isatin.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Humans; In Vitro Techniques; Isatin; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Neoplasms; Schiff Bases; Xenograft Model Antitumor Assays | 2014 |
Imaging caspase-3 activation as a marker of apoptosis-targeted treatment response in cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Female; Fluorine Radioisotopes; HeLa Cells; Humans; Immunohistochemistry; Inhibitory Concentration 50; Isatin; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, TNF-Related Apoptosis-Inducing Ligand; Sulfonamides; Tissue Distribution | 2015 |
Isatin derivatives with activity against apoptosis-resistant cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Isatin; Molecular Structure; Neoplasms; Structure-Activity Relationship | 2016 |
Design, synthesis, and biological characterization of a caspase 3/7 selective isatin labeled with 2-[18F]fluoroethylazide.
Topics: Animals; Azides; Caspase 3; Caspase Inhibitors; Chemistry, Pharmaceutical; Drug Design; Enzyme Activation; Enzyme Inhibitors; Fluorine Radioisotopes; Humans; Isatin; Male; Mice; Neoplasm Transplantation; Neoplasms; Radiopharmaceuticals | 2008 |