irsogladine has been researched along with Peptic Ulcer in 3 studies
irsogladine: RN given refers to parent cpd; MN 1695 refers to maleate salt
Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we compare the efficacy of the gastromucoprotective drug irsogladine with omeprazole in preventing NSAID-induced esophagitis, peptic ulcers, and small-intestinal mucosal injury in healthy subjects." | 9.17 | Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study. ( Abe, Y; Higuchi, K; Inoue, T; Ishida, K; Kawakami, K; Kojima, Y; Kuramoto, T; Murano, M; Narabayashi, K; Nouda, S; Takeuchi, T; Tokioka, S; Umegaki, E; Yoda, Y, 2013) |
| " Here, we compare the efficacy of the gastromucoprotective drug irsogladine with omeprazole in preventing NSAID-induced esophagitis, peptic ulcers, and small-intestinal mucosal injury in healthy subjects." | 5.17 | Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study. ( Abe, Y; Higuchi, K; Inoue, T; Ishida, K; Kawakami, K; Kojima, Y; Kuramoto, T; Murano, M; Narabayashi, K; Nouda, S; Takeuchi, T; Tokioka, S; Umegaki, E; Yoda, Y, 2013) |
| "Irsogladine, a mucosal protective drug, was developed in Japan for the treatment of peptic ulcer disease and acute gastritis." | 4.89 | Irsogladine: overview of the mechanisms of mucosal protective and healing- promoting actions in the gastrointestinal tract. ( Akagi, M; Amagase, K; Murakami, T; Takeuchi, K, 2013) |
| "Irsogladine maleate was effective for reducing NSAID-induced small-intestinal mucosal injury." | 2.79 | Irsogladine improves small-intestinal injuries in regular users of nonsteroidal anti-inflammatory drugs. ( Hirata, Y; Isomura, Y; Kobayashi, Y; Koike, K; Suzuki, H; Watabe, H; Watanabe, Y; Yamada, A; Yamaji, Y; Yoshida, H; Yoshida, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuramoto, T | 1 |
| Umegaki, E | 1 |
| Nouda, S | 1 |
| Narabayashi, K | 1 |
| Kojima, Y | 1 |
| Yoda, Y | 1 |
| Ishida, K | 1 |
| Kawakami, K | 1 |
| Abe, Y | 1 |
| Takeuchi, T | 1 |
| Inoue, T | 1 |
| Murano, M | 1 |
| Tokioka, S | 1 |
| Higuchi, K | 1 |
| Isomura, Y | 1 |
| Yamaji, Y | 1 |
| Yamada, A | 1 |
| Watanabe, Y | 1 |
| Suzuki, H | 1 |
| Kobayashi, Y | 1 |
| Yoshida, S | 1 |
| Watabe, H | 1 |
| Hirata, Y | 1 |
| Yoshida, H | 1 |
| Koike, K | 1 |
| Akagi, M | 1 |
| Amagase, K | 1 |
| Murakami, T | 1 |
| Takeuchi, K | 1 |
1 review available for irsogladine and Peptic Ulcer
| Article | Year |
|---|---|
Irsogladine: overview of the mechanisms of mucosal protective and healing- promoting actions in the gastrointestinal tract.
Topics: Animals; Anti-Ulcer Agents; Gastric Mucosa; Gastritis; Gastrointestinal Diseases; Helicobacter Infec | 2013 |
2 trials available for irsogladine and Peptic Ulcer
| Article | Year |
|---|---|
Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Endoscopy, Gastrointe | 2013 |
Irsogladine improves small-intestinal injuries in regular users of nonsteroidal anti-inflammatory drugs.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule | 2014 |