irsogladine has been researched along with Colitis in 2 studies
irsogladine: RN given refers to parent cpd; MN 1695 refers to maleate salt
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To investigate the therapeutic approach to intestinal fibrosis, we have developed a mouse model of intestinal fibrosis by administering dextran sulfate sodium (DSS) and examining the effects of irsogladine maleate (IM) [2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate], which has been widely used as an antiulcer drug for gastric mucosa in Japan, on DDS-induced chronic colitis." | 7.78 | Irsogladine maleate ameliorates inflammation and fibrosis in mice with chronic colitis induced by dextran sulfate sodium. ( Asakura, H; Kawachi, H; Kawase, T; Kawauchi, Y; Nagata, M; Sukumaran, V; Suzuki, K; Takagi, R; Thandavarayan, RA; Tomita, M; Watanabe, K; Yamaguchi, H; Yokoyama, J; Yoneyama, H, 2012) |
| " To investigate the therapeutic approach to intestinal fibrosis, we have developed a mouse model of intestinal fibrosis by administering dextran sulfate sodium (DSS) and examining the effects of irsogladine maleate (IM) [2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate], which has been widely used as an antiulcer drug for gastric mucosa in Japan, on DDS-induced chronic colitis." | 3.78 | Irsogladine maleate ameliorates inflammation and fibrosis in mice with chronic colitis induced by dextran sulfate sodium. ( Asakura, H; Kawachi, H; Kawase, T; Kawauchi, Y; Nagata, M; Sukumaran, V; Suzuki, K; Takagi, R; Thandavarayan, RA; Tomita, M; Watanabe, K; Yamaguchi, H; Yokoyama, J; Yoneyama, H, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakagawa, T | 1 |
| Katsuno, T | 1 |
| Noguchi, Y | 1 |
| Mandai, Y | 1 |
| Yoshihama, S | 1 |
| Saito, K | 1 |
| Maruoka, D | 1 |
| Matsumura, T | 1 |
| Arai, M | 1 |
| Yokosuka, O | 1 |
| Yamaguchi, H | 1 |
| Suzuki, K | 1 |
| Nagata, M | 1 |
| Kawase, T | 1 |
| Sukumaran, V | 1 |
| Thandavarayan, RA | 1 |
| Kawauchi, Y | 1 |
| Yokoyama, J | 1 |
| Tomita, M | 1 |
| Kawachi, H | 1 |
| Watanabe, K | 1 |
| Yoneyama, H | 1 |
| Asakura, H | 1 |
| Takagi, R | 1 |
2 other studies available for irsogladine and Colitis
| Article | Year |
|---|---|
Irsogladine Maleate Prevents Colitis in Interleukin-10 Gene-Deficient Mice by Reducing Interleukin-12 and -23 Production.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colon; Cytokines; Interleukin-10; Interleukin-12; Interl | 2015 |
Irsogladine maleate ameliorates inflammation and fibrosis in mice with chronic colitis induced by dextran sulfate sodium.
Topics: Animals; Anti-Ulcer Agents; Chronic Disease; Colitis; Dextran Sulfate; Disease Models, Animal; Femal | 2012 |