Page last updated: 2024-09-04

irofulven and Adenocarcinoma, Basal Cell

irofulven has been researched along with Adenocarcinoma, Basal Cell in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's8 (80.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chimmani, R; Gurram, M; Kelner, MJ; McMorris, TC; Staake, MD1
Alisala, K; Banda, G; Chimmani, R; Kelner, MJ; McMorris, TC; Staake, MD1
Kelner, MJ; McMorris, TC; Staake, MD1
Blessing, JA; Pearl, ML; Rose, PG; Schilder, RJ1
Arsenau, J; Berman, B; MacDonald, JR; Richards, D; Senzer, N; Smith, S1
Beale, P; Boyer, M; Chan, AT; Chung, HC; Clarke, S; Goh, BC; Ho, R; Jeung, HC; Lam, KC; Lim, R; Ma, B; Mo, FK; Ng, EK; Ong, SY; Rha, SY; Roh, JK; Soo, R; Yeo, W; Zee, B1
Bossi, A; Chauchereau, A; de Crevoisier, R; Di Palma, M; Escudier, B; Fizazi, K; Gross-Goupil, M; Massard, C; Thuret, R1
Estes, L; Kelner, MJ; McMorris, TC; Samson, KM; Taetle, R; Wang, W1
Herman, TS; MacDonald, JR; Roberts, K; Woynarowska, BA; Woynarowski, JM1
Kashimoto, S; MacDonald, JR; Nakano, K; Sato, Y1

Trials

3 trial(s) available for irofulven and Adenocarcinoma, Basal Cell

ArticleYear
Evaluation of irofulven (MGI-114) in the treatment of recurrent or persistent endometrial carcinoma: A phase II study of the Gynecologic Oncology Group.
    Investigational new drugs, 2004, Volume: 22, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Dose-Response Relationship, Drug; Endometrial Neoplasms; Female; Hematologic Diseases; Humans; Middle Aged; Nausea; Neoplasm Recurrence, Local; Sesquiterpenes; Treatment Outcome; Vomiting

2004
Irofulven demonstrates clinical activity against metastatic hormone-refractory prostate cancer in a phase 2 single-agent trial.
    American journal of clinical oncology, 2005, Volume: 28, Issue:1

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Sesquiterpenes; Survival Analysis

2005
Irofulven as first line therapy in recurrent or metastatic gastric cancer: a phase II multicenter study by the Cancer Therapeutics Research Group (CTRG).
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Alkylating; Female; Humans; Infusions, Intravenous; Lymph Nodes; Male; Middle Aged; Neoplasm Recurrence, Local; Sesquiterpenes; Stomach Neoplasms; Survival Rate; Treatment Outcome

2007

Other Studies

7 other study(ies) available for irofulven and Adenocarcinoma, Basal Cell

ArticleYear
Synthesis and antitumor activity of amine analogs of irofulven.
    Bioorganic & medicinal chemistry letters, 2007, Dec-15, Volume: 17, Issue:24

    Topics: Adenocarcinoma; Amines; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Survival; Humans; Inhibitory Concentration 50; Molecular Structure; Sesquiterpenes; Structure-Activity Relationship

2007
Structure-activity studies of urea, carbamate, and sulfonamide derivatives of acylfulvene.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Adenocarcinoma; Animals; B-Lymphocytes; Carbamates; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Lung Neoplasms; Mice; Sesquiterpenes; Spiro Compounds; Structure-Activity Relationship; Sulfonamides; Urea

2010
Synthesis and biological activity of enantiomers of antitumor irofulven.
    The Journal of organic chemistry, 2004, Feb-06, Volume: 69, Issue:3

    Topics: Acylation; Adenocarcinoma; Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Mice; Molecular Structure; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship

2004
The postchemotherapy PSA surge syndrome.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Docetaxel; Estramustine; Gonadotropin-Releasing Hormone; Humans; Kinetics; Male; Middle Aged; Mitoxantrone; Neoplasm Metastasis; Orchiectomy; Prednisone; Prostate-Specific Antigen; Prostatic Neoplasms; Sesquiterpenes; Syndrome; Taxoids; Treatment Outcome

2008
Efficacy of HMAF (MGI-114) in the MV522 metastatic lung carcinoma xenograft model nonresponsive to traditional anticancer agents.
    Investigational new drugs, 1996, Volume: 14, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Sesquiterpenes; Transplantation, Heterologous

1996
Targeting apoptosis by hydroxymethylacylfulvene in combination with gamma radiation in prostate tumor cells.
    Radiation research, 2000, Volume: 154, Issue:4

    Topics: Adenocarcinoma; Androgens; Antineoplastic Agents, Alkylating; Apoptosis; Combined Modality Therapy; DNA Damage; Gamma Rays; Humans; Intestinal Mucosa; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Radiation Tolerance; Radiation-Sensitizing Agents; Sesquiterpenes; Tumor Cells, Cultured; Tumor Stem Cell Assay

2000
In vivo antitumour efficacy of MGI-114 (6-hydroxymethylacylfulvene, HMAF) in various human tumour xenograft models including several lung and gastric tumours.
    European journal of cancer (Oxford, England : 1990), 2001, Volume: 37, Issue:11

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Alkylating; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Colonic Neoplasms; Humans; Lung Neoplasms; Melanoma; Mice; Mice, Nude; Sesquiterpenes; Stomach Neoplasms; Xenograft Model Antitumor Assays

2001