Page last updated: 2024-08-24

irinotecan and Sarcoma

irinotecan has been researched along with Sarcoma in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's4 (33.33)29.6817
2010's3 (25.00)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
B, H; Canute Fernandes, S; Rastogi, S1
Bisogno, G; Bogart, E; Calareso, G; Casanova, M; Chisholm, JC; Defachelles, AS; Gatz, SA; Le Deley, MC; McHugh, K; Melcon, SG; Merks, JHM; Minard-Colin, V; Probst, A; Rocourt, N; van Rijn, RR1
Burrow, TA; Eslinger, C; Koneru, B; Macha, SJ; McCoy, K; Nance, J; Rahman, RL; Reynolds, CP; Ronaghan, CA; Savitski, D; Zhu, C1
Balaguer-Lluna, L; Baulenas-Farres, M; Burgueño, V; Carcaboso, AM; Carrasco, R; Castañeda, A; Castillo-Ecija, H; Celis, V; Cruz, O; Cuadrado-Vilanova, M; Garraus, M; Gorostegui, M; Jimenez-Cabaco, A; Krauel, L; Lavarino, C; Manzanares, A; Monterrubio, C; Mora, J; Morales La Madrid, A; Muñoz-Aznar, O; Olaciregui, NG; Pascual-Pasto, G; Perez-Jaume, S; Resa-Pares, C; Salvador, N; Santa-Maria, V; Suñol, M; Torner, F; Vancells, M; Vicario, FJ; Vila-Ubach, M1
Blaydorn, L; Coats, J; Farley, JH; Khemka, V; Lynch, CA; McGahey, K; Niu, J; Sangal, A; Waypa, J; Weiss, GJ1
Ambati, SR; Chaudhry, A; Lopes, EC; Moore, MA; Pera, B; Saxena, A; Shieh, JH; Su, TL; Wong, EW1
Attinà, G; Coccia, P; Riccardi, R; Ruggiero, A; Scalzone, M1
Choijamts, B; Emoto, M; Kawarabayashi, T; Miyamoto, S; Naganuma, Y; Nakajima, K; Tachibana, K1
Patel, SR1
Arcamone, G; Bertolini, P; Bisogno, G; Carli, M; Paolucci, P; Prete, A; Provenzi, M; Riccardi, R; Ruggiero, A; Surico, G1
Gupta, AA; Pappo, AS1
Boven, E; Erkelens, CA; Jansen, WJ; Kolfschoten, GM; Pinedo, HM; Van Ark-Otte, J1

Reviews

2 review(s) available for irinotecan and Sarcoma

ArticleYear
Developing therapeutic pharmaceuticals for the treatment of soft-tissue sarcomas.
    Expert opinion on investigational drugs, 2002, Volume: 11, Issue:12

    Topics: Antineoplastic Agents; Benzamides; Camptothecin; Dacarbazine; Deoxycytidine; Dioxoles; Gemcitabine; Humans; Imatinib Mesylate; Irinotecan; Isoquinolines; Piperazines; Pyrimidines; Sarcoma; Temozolomide; Tetrahydroisoquinolines; Trabectedin

2002
New drugs for the treatment of metastatic or refractory soft tissue sarcomas in children.
    Future oncology (London, England), 2006, Volume: 2, Issue:5

    Topics: Animals; Camptothecin; Child; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Humans; Irinotecan; Rhabdomyosarcoma; Sarcoma; Survival Rate; Topoisomerase I Inhibitors; Topotecan

2006

Trials

2 trial(s) available for irinotecan and Sarcoma

ArticleYear
A phase Ib study of pembrolizumab plus chemotherapy in patients with advanced cancer (PembroPlus).
    British journal of cancer, 2017, Jun-27, Volume: 117, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Albumins; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Camptothecin; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Diarrhea; Docetaxel; Doxorubicin; Drug Eruptions; Fatigue; Female; Gemcitabine; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasms; Ovarian Neoplasms; Paclitaxel; Pancreatic Neoplasms; Polyethylene Glycols; Sarcoma; Small Cell Lung Carcinoma; Taxoids; Treatment Outcome; Vinblastine; Vinorelbine; Vomiting

2017
Phase II study of a protracted irinotecan schedule in children with refractory or recurrent soft tissue sarcoma.
    Cancer, 2006, Feb-01, Volume: 106, Issue:3

    Topics: Adolescent; Antineoplastic Agents, Phytogenic; Camptothecin; Child; Child, Preschool; Disease Progression; Drug Administration Schedule; Female; Humans; Infant; Infusions, Intravenous; Irinotecan; Male; Neutropenia; Sarcoma; Soft Tissue Neoplasms; Treatment Outcome

2006

Other Studies

8 other study(ies) available for irinotecan and Sarcoma

ArticleYear
VIT-0910: Need for Cautious Optimism?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022, 03-20, Volume: 40, Issue:9

    Topics: Adult; Child; Humans; Irinotecan; Rhabdomyosarcoma; Sarcoma; Temozolomide; Therapies, Investigational; Vincristine

2022
Reply to H. B et al.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022, 03-20, Volume: 40, Issue:9

    Topics: Child; Humans; Irinotecan; Rhabdomyosarcoma; Sarcoma; Temozolomide; Therapies, Investigational; Vincristine

2022
Alternative Lengthening of Telomeres in Cancer Confers a Vulnerability to Reactivation of p53 Function.
    Cancer research, 2022, Sep-16, Volume: 82, Issue:18

    Topics: Animals; Carcinoma; Humans; Irinotecan; Mice; Neuroblastoma; Sarcoma; Telomerase; Telomere; Telomere Homeostasis; Tumor Suppressor Protein p53

2022
Prognostic value of patient-derived xenograft engraftment in pediatric sarcomas.
    The journal of pathology. Clinical research, 2021, Volume: 7, Issue:4

    Topics: Adolescent; Animals; Child; Child, Preschool; Disease Models, Animal; Female; Heterografts; Humans; Irinotecan; Male; Mice; Osteosarcoma; Prognosis; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Treatment Outcome; Xenograft Model Antitumor Assays

2021
BO-1055, a novel DNA cross-linking agent with remarkable low myelotoxicity shows potent activity in sarcoma models.
    Oncotarget, 2016, Jul-12, Volume: 7, Issue:28

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Camptothecin; Cell Line, Tumor; Cell Proliferation; DNA Damage; Drug Synergism; HCT116 Cells; Humans; Irinotecan; MCF-7 Cells; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Nitrogen Mustard Compounds; Phenylurea Compounds; Sarcoma; Xenograft Model Antitumor Assays

2016
Treatment of childhood sarcoma with irinotecan: bilirubin level as a predictor of gastrointestinal toxicity.
    Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:6

    Topics: Adolescent; Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Child; Child, Preschool; Diarrhea; Female; Gastric Mucosa; Humans; Infant; Intestinal Mucosa; Irinotecan; Male; Predictive Value of Tests; Retrospective Studies; Sarcoma; Soft Tissue Neoplasms

2009
Metronomic irinotecan chemotherapy combined with ultrasound irradiation for a human uterine sarcoma xenograft.
    Cancer science, 2011, Volume: 102, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Separation; Combined Modality Therapy; Drug Administration Schedule; Female; Flow Cytometry; Humans; Irinotecan; Mice; Mice, Nude; Neovascularization, Pathologic; Sarcoma; Ultrasonic Therapy; Uterine Neoplasms; Xenograft Model Antitumor Assays

2011
Anti-tumor activity of CPT-11 in experimental human ovarian cancer and human soft-tissue sarcoma.
    International journal of cancer, 1997, Dec-10, Volume: 73, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; DNA Topoisomerases, Type I; Drug Screening Assays, Antitumor; Female; Humans; Injections, Intraperitoneal; Injections, Intravenous; Irinotecan; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; RNA, Messenger; Sarcoma; Sarcoma, Experimental; Tumor Cells, Cultured

1997