Page last updated: 2024-08-24

irinotecan and Renal Insufficiency

irinotecan has been researched along with Renal Insufficiency in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Akiyama, Y; Ando, Y; Fujita, K; Hirose, T; Ichikawa, W; Ishida, H; Kawara, K; Miwa, K; Miya, T; Mizuno, K; Nagashima, F; Narabayashi, M; Saji, S; Sasaki, Y; Sugiyama, M; Sunakawa, Y; Yamamoto, W; Yamashita, K1
Ariizumi, H; Fujita, KI; Hirasawa, Y; Ishida, H; Ishiguro, T; Kondo, Y; Kubota, Y; Kusuhara, H; Matsumoto, N; Ohkuma, R; Sasaki, Y; Tomoda, Y; Tsuboya, A; Tsunoda, T1
Fujita, K; Sasaki, Y1
Armstrong, AE; Cohn, RA; Dargart, J; Gosiengfiao, Y; Matossian, D; Reichek, J; Walterhouse, DO1
Cheung, WY; Gill, S; Ho, MY; Kennecke, HF; Lim, HJ; Renouf, DJ1
Seiter, K1

Reviews

2 review(s) available for irinotecan and Renal Insufficiency

ArticleYear
Optimization of cancer chemotherapy on the basis of pharmacokinetics and pharmacodynamics: from patients enrolled in clinical trials to those in the 'real world'.
    Drug metabolism and pharmacokinetics, 2014, Volume: 29, Issue:1

    Topics: Age Factors; Antineoplastic Agents; Camptothecin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Monitoring; Humans; Irinotecan; Neoplasms; Obesity; Oxonic Acid; Patient Selection; Polypharmacy; Renal Insufficiency; Tegafur

2014
Toxicity of the topoisomerase I inhibitors.
    Expert opinion on drug safety, 2005, Volume: 4, Issue:1

    Topics: Camptothecin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Irinotecan; Renal Insufficiency; Topoisomerase I Inhibitors; Topotecan

2005

Trials

1 trial(s) available for irinotecan and Renal Insufficiency

ArticleYear
Delayed elimination of SN-38 in cancer patients with severe renal failure.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Female; Genotype; Glucuronides; Glucuronosyltransferase; Humans; Irinotecan; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Prospective Studies; Renal Dialysis; Renal Insufficiency

2011

Other Studies

3 other study(ies) available for irinotecan and Renal Insufficiency

ArticleYear
Minimal contribution of the hepatic uptake transporter OATP1B1 to the inter-individual variability in SN-38 pharmacokinetics in cancer patients without severe renal failure.
    Cancer chemotherapy and pharmacology, 2021, Volume: 88, Issue:3

    Topics: Aged; Area Under Curve; Chromatography, Liquid; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Humans; Irinotecan; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Neoplasms; Prospective Studies; Renal Insufficiency; Severity of Illness Index; Tandem Mass Spectrometry; Topoisomerase I Inhibitors

2021
Irinotecan and temozolomide for treatment of neuroblastoma in a patient with renal failure on hemodialysis.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Child; Dacarbazine; Female; Humans; Irinotecan; Neuroblastoma; Renal Dialysis; Renal Insufficiency; Temozolomide; Treatment Outcome

2014
Defining Eligibility of FOLFIRINOX for First-Line Metastatic Pancreatic Adenocarcinoma (MPC) in the Province of British Columbia: A Population-based Retrospective Study.
    American journal of clinical oncology, 2017, Volume: 40, Issue:6

    Topics: Activities of Daily Living; Adenocarcinoma; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; British Columbia; Camptothecin; Eligibility Determination; Female; Fluorouracil; Humans; Hyperbilirubinemia; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Peritoneal Neoplasms; Renal Insufficiency; Retrospective Studies

2017