Page last updated: 2024-08-24

irinotecan and Melanoma

irinotecan has been researched along with Melanoma in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.11)18.2507
2000's4 (22.22)29.6817
2010's9 (50.00)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Falzone, L; Gattuso, G; Libra, M; Ricci, D; Salemi, R; Santagati, M; Scillato, M; Vivarelli, S1
Hosokawa, M; Kono, Y; Ogawara, KI; Tetsumoto, S; Yasui, M1
Bolouri, MR; Dorafshan, S; Ghods, R; Madjd, Z; Mahmoudi, AR; Mahmoudian, J; Rahdan, S; Rakhshan, A; Shekarabi, M; Shokri, MR; Zarnani, AH1
Cardillo, TM; Chang, CH; Goldenberg, DM; Govindan, SV; Rossi, DL; Wang, Y; Zalath, MB1
Amaria, R; Ashkin, E; Bernatchez, C; Chen, Y; Davis, RE; Devi, S; Forget, MA; Haymaker, C; Heffernan, T; Hu, J; Huang, L; Hwu, P; Kalra, A; Liu, C; Malu, S; Mbofung, RM; McKenzie, JA; Muller, F; Peng, W; Pradeep, S; Roszik, J; Satani, N; Sood, A; Tieu, T; Williams, L; Xu, C; Zhang, M; Zorro Manrique, S1
Hou, B; Hu, X; Lai, Y; Lei, L; Tian, Y; Wang, Y; Xu, J; Xu, Z; Yu, H; Zhang, W1
Aliberti, C; Bazzi, M; Campana, LG; Chiarion-Sileni, V; Midena, E; Parrozzani, R; Pigozzo, J; Pilati, P; Valpione, S1
Berntzen, DT; Carling, U; Dorenberg, EJ; Dueland, S; Edwin, B; Eide, NA; Haugvik, SP; Røsok, B1
Arifa, RDN; Barcelos, LS; Garcia, ZM; Krambrock, K; Ladeira, LO; Lima, RL; Madeira, MFM; Paula, TP; Pinheiro, MVB; Pinho, V; Souza, DG; Teixeira, MM; Ÿvila, TV1
Aboody, KS; Chen, MY; Gutova, M; Kim, SU; Najbauer, J; Potter, PM1
Balivada, S; Basel, MT; Bossmann, SH; Myers, C; Pyle, M; Rachakatla, RS; Seo, GM; Shrestha, TB; Tamura, M; Troyer, DL; Wang, H1
Agostini, G; Aldrighetti, L; Cappio, S; De Cobelli, F; Del Maschio, A; Losio, C; Orsi, M; Pilla, L; Ratti, F; Venturini, M1
Aydiner, A; Camlica, H; Kurul, S; Tas, F; Topuz, E1
Duncan, J; McLeod, HL; Scheffer, GL; Scheper, RJ; Shannon, WD; Zhang, W1
Gao, K; Lam, W; Li, G; Li, J; Lockwood, WW1
Aoyagi, K; Aoyagi, Y; Asao, T; Okazaki, S; Sano, M; Utsugi, T; Wierzba, K; Yamada, Y1
Boven, E; Hausheer, FH; Pinedo, HM; Schlüper, HM; Van Hattum, AH1
Slichenmyer, WJ; Von Hoff, DD1

Reviews

1 review(s) available for irinotecan and Melanoma

ArticleYear
New natural products in cancer chemotherapy.
    Journal of clinical pharmacology, 1990, Volume: 30, Issue:9

    Topics: Adenocarcinoma; Alkaloids; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Drugs, Investigational; Harringtonines; Homoharringtonine; Humans; Infusions, Intravenous; Irinotecan; Melanoma; Paclitaxel; Phytotherapy; Plant Extracts; Plants, Medicinal; Topotecan

1990

Trials

2 trial(s) available for irinotecan and Melanoma

ArticleYear
Transarterial chemoembolization with drug-eluting beads preloaded with irinotecan as a first-line approach in uveal melanoma liver metastases: tumor response and predictive value of diffusion-weighted MR imaging in five patients.
    Journal of vascular and interventional radiology : JVIR, 2012, Volume: 23, Issue:7

    Topics: Aged; Antineoplastic Agents; Camptothecin; Chemoembolization, Therapeutic; Chemotherapy, Adjuvant; Delayed-Action Preparations; Diffusion Magnetic Resonance Imaging; Female; Humans; Irinotecan; Liver Neoplasms; Magnetic Resonance Angiography; Male; Melanoma; Microspheres; Middle Aged; Prognosis; Treatment Outcome; Uveal Neoplasms

2012
Combination chemotherapy with docetaxel and irinotecan in metastatic malignant melanoma.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2003, Volume: 15, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Docetaxel; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Irinotecan; Male; Melanoma; Middle Aged; Paclitaxel; Skin Neoplasms; Survival Analysis; Taxoids; Treatment Outcome

2003

Other Studies

15 other study(ies) available for irinotecan and Melanoma

ArticleYear
Lactobacillus rhamnosus GG cell-free supernatant as a novel anti-cancer adjuvant.
    Journal of translational medicine, 2023, 03-14, Volume: 21, Issue:1

    Topics: Adjuvants, Immunologic; Colon; Humans; Irinotecan; Lacticaseibacillus rhamnosus; Melanoma; Probiotics; Propidium

2023
3-deazaneplanocin A, a histone methyltransferase inhibitor, improved the chemoresistance induced under hypoxia in melanoma cells.
    Biochemical and biophysical research communications, 2023, 10-15, Volume: 677

    Topics: Animals; Cell Line, Tumor; DNA Methylation; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Histone Methyltransferases; Histones; Humans; Irinotecan; Melanoma; Mice; RNA, Small Interfering; Tumor Microenvironment

2023
Discovery of a potential biomarker for immunotherapy of melanoma: PLAC1 as an emerging target.
    Immunopharmacology and immunotoxicology, 2020, Volume: 42, Issue:6

    Topics: Antineoplastic Agents, Immunological; Biomarkers, Tumor; Cell Line, Tumor; Female; Humans; Immunoconjugates; Immunotherapy; Irinotecan; Male; Melanoma; Middle Aged; Molecular Targeted Therapy; Pregnancy Proteins; Skin Neoplasms; Topoisomerase I Inhibitors

2020
IMMU-140, a Novel SN-38 Antibody-Drug Conjugate Targeting HLA-DR, Mediates Dual Cytotoxic Effects in Hematologic Cancers and Malignant Melanoma.
    Molecular cancer therapeutics, 2018, Volume: 17, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Apoptosis; Cell Line, Tumor; Hematologic Neoplasms; HLA-DR Antigens; Humans; Immunoconjugates; Immunoglobulin G; Irinotecan; Melanoma; Mice

2018
The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy.
    Journal of the National Cancer Institute, 2018, 07-01, Volume: 110, Issue:7

    Topics: Animals; Cell Line, Tumor; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Humans; Immunotherapy, Adoptive; Irinotecan; Lymphocytes, Tumor-Infiltrating; Melanoma; Mice; Mice, Inbred C57BL; T-Lymphocytes, Cytotoxic; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Tumor Microenvironment; Xenograft Model Antitumor Assays

2018
Bioinspired Multivalent Peptide Nanotubes for Sialic Acid Targeting and Imaging-Guided Treatment of Metastatic Melanoma.
    Small (Weinheim an der Bergstrasse, Germany), 2019, Volume: 15, Issue:22

    Topics: Animals; Boronic Acids; Humans; Irinotecan; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; N-Acetylneuraminic Acid; Nanotubes, Peptide; Topoisomerase I Inhibitors

2019
A retrospective analysis of 141 patients with liver metastases from uveal melanoma: a two-cohort study comparing transarterial chemoembolization with CPT-11 charged microbeads and historical treatments.
    Melanoma research, 2015, Volume: 25, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Chemoembolization, Therapeutic; Databases, Factual; Feasibility Studies; Female; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Male; Melanoma; Middle Aged; Proportional Hazards Models; Retrospective Studies; Risk Factors; Treatment Outcome; Uveal Neoplasms; Young Adult

2015
Transarterial Chemoembolization of Liver Metastases from Uveal Melanoma Using Irinotecan-Loaded Beads: Treatment Response and Complications.
    Cardiovascular and interventional radiology, 2015, Volume: 38, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Contrast Media; Drug Delivery Systems; Female; Humans; Irinotecan; Liver; Liver Neoplasms; Male; Melanoma; Middle Aged; Radiographic Image Enhancement; Retrospective Studies; Therapeutics; Tomography, X-Ray Computed; Uveal Neoplasms; Young Adult

2015
The reduction of oxidative stress by nanocomposite Fullerol decreases mucositis severity and reverts leukopenia induced by Irinotecan.
    Pharmacological research, 2016, Volume: 107

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Fullerenes; Glutathione; Ileum; Interleukin-1beta; Intestinal Mucosa; Irinotecan; Leukopenia; Male; Melanoma; Mice, Inbred C57BL; Mice, Transgenic; Mucositis; Nanocomposites; Oxidative Stress; Peroxidase; Thiobarbituric Acid Reactive Substances; Tumor Burden

2016
Therapeutic targeting of melanoma cells using neural stem cells expressing carboxylesterase, a CPT-11 activating enzyme.
    Current stem cell research & therapy, 2010, Volume: 5, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carboxylesterase; Cell Line, Tumor; Cell Movement; Cytokines; Enzyme Inhibitors; Humans; Irinotecan; Melanoma; Neurons; Rabbits; Stem Cells

2010
A self-contained enzyme activating prodrug cytotherapy for preclinical melanoma.
    Molecular biology reports, 2012, Volume: 39, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carboxylesterase; Cell Transplantation; DNA Primers; Drug Carriers; Drug Evaluation, Preclinical; Female; Genes, Transgenic, Suicide; Irinotecan; Lung Neoplasms; Magnetics; Melanoma; Mice; Mice, Inbred C57BL; Monocyte-Macrophage Precursor Cells; Nanoparticles; Prodrugs

2012
Expression of drug pathway proteins is independent of tumour type.
    The Journal of pathology, 2006, Volume: 209, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Breast Neoplasms; Camptothecin; Colonic Neoplasms; Cytochrome P-450 Enzyme System; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Immunohistochemistry; Irinotecan; Lung Neoplasms; Lymphoma; Male; Melanoma; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms; Tissue Array Analysis

2006
Genomic analyses identify gene candidates for acquired irinotecan resistance in melanoma cells.
    International journal of oncology, 2008, Volume: 32, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Camptothecin; Chromosomes, Human, Pair 14; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Melanoma; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2008
Antitumor activity of a novel quinoline derivative, TAS-103, with inhibitory effects on topoisomerases I and II.
    Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:10

    Topics: Adenocarcinoma; Aminoquinolines; Animals; Antineoplastic Agents; Camptothecin; Cisplatin; Colonic Neoplasms; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Etoposide; Humans; Indenes; Indoles; Irinotecan; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Pyridines; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1997
New highly lipophilic camptothecin BNP1350 is an effective drug in experimental human cancer.
    International journal of cancer, 2000, Oct-15, Volume: 88, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Colonic Neoplasms; Doxorubicin; Drug Resistance, Multiple; Enzyme Inhibitors; Female; Humans; Irinotecan; Lung Neoplasms; Melanoma; Mice; Mice, Nude; Neoplasms; Ovarian Neoplasms; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2000