Page last updated: 2024-08-24

irinotecan and Lymphoma

irinotecan has been researched along with Lymphoma in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (20.00)18.2507
2000's10 (50.00)29.6817
2010's6 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boku, N; Fujiki, T; Fujino, K; Gemma, A; Kakihata, K; Masatani, S; Morita, S; Shiozawa, T; Tadokoro, J1
Jin, J; Joo, KM; Kang, W; Kim, KH; Kim, SU; Lee, JI; Nam, DH; Seol, HJ; Yang, H1
Abraham, WD; Bustamante López, SC; Huang, B; Irvine, DJ; Luo, SS; Zheng, Y1
Colcher, D; Davis, ME; Duringer, J; Forman, SJ; Kretzner, L; Numbenjapon, T; Raubitschek, A; Schluep, T; Wang, J; Yen, Y1
Burckhardt, G; Gupta, S; Hagos, Y; Henjakovic, M; Koepsell, H; Wulf, G1
Manabe, S; Matsumura, Y; Tarin, D; Yasunaga, M1
Aibe, H; Asayama, Y; Honda, H; Irie, H; Kakihara, D; Matake, K; Nakamura, K; Nakayama, T; Nishie, A; Ohga, S; Tajima, T; Yamamoto, N; Yoshimitsu, K1
Maeda, K; Okamura, S; Shibuya, T; Suzumiya, J; Suzushima, H; Tamura, K; Utsunomiya, A1
Innocenti, F; Mani, S; Prado, M; Ramírez, J; Ratain, MJ; Schilsky, RL; Undevia, SD; Vogelzang, NJ1
Anderson, KC; Burger, R; Catley, L; Chauhan, D; Denis, L; Hideshima, T; Munshi, NC; Podar, K; Richardson, P; Shringarpure, R; Son, MT; Tai, YT; Tassone, P1
Duncan, J; McLeod, HL; Scheffer, GL; Scheper, RJ; Shannon, WD; Zhang, W1
Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Kobayashi, H; Mano, H; Tsunoda, S1
Booth, BP; Gobburu, JV; Ibrahim, A; Innocenti, F; Johnson, JR; Mehta, M; Rahman, A; Ramchandani, RP; Ratain, MJ; Wang, Y1
Adams, DJ; Giles, F; Jacobsen, TF; Myhren, F; Rizzieri, DA; Sandvold, ML1
Ariyoshi, Y; Ogawa, M1
Kizaki, H; Oguro, M; Onishi, Y1
Rosen, LS1
Adams, DJ; Bass, AJ; Davis, P; DeCastro, CM; Foster, T; Gockerman, JP; Hammett, E; Moore, JO; Payne, N; Rizzieri, DA; Rosner, GL1
Arima, T; Ariyoshi, H; Ichimaru, M; Kuramoto, A; Masaoka, T; Oguro, M; Ohno, R; Okada, K; Sakai, Y; Yoshida, Y1

Reviews

2 review(s) available for irinotecan and Lymphoma

ArticleYear
[Clinical trials of new antitumor drugs in hematopoietic malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 3

    Topics: Acute Disease; Antineoplastic Agents, Phytogenic; Camptothecin; Clinical Trials as Topic; Doxorubicin; Ethics, Medical; Humans; Idarubicin; Irinotecan; Leukemia; Lymphoma

1994
Irinotecan in lymphoma, leukemia, and breast, pancreatic, ovarian, and small-cell lung cancers.
    Oncology (Williston Park, N.Y.), 1998, Volume: 12, Issue:8 Suppl 6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Carcinoma, Non-Small-Cell Lung; Female; Humans; Irinotecan; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms

1998

Trials

3 trial(s) available for irinotecan and Lymphoma

ArticleYear
Phase I study of the combination of irinotecan hydrochloride, carboplatin, and dexamethasone for the treatment of relapsed or refractory malignant lymphoma.
    International journal of hematology, 2004, Volume: 79, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Dexamethasone; Female; Humans; Irinotecan; Lymphoma; Male; Maximum Tolerated Dose; Middle Aged; Salvage Therapy; Treatment Outcome

2004
A phase I trial of pharmacologic modulation of irinotecan with cyclosporine and phenobarbital.
    Clinical pharmacology and therapeutics, 2004, Volume: 76, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Area Under Curve; Camptothecin; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Drug Therapy, Combination; Endpoint Determination; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Half-Life; Humans; Hypnotics and Sedatives; Immunosuppressive Agents; Irinotecan; Lymphoma; Male; Middle Aged; Neoplasms; Phenobarbital

2004
Phase I evaluation of prolonged-infusion gemcitabine with irinotecan for relapsed or refractory leukemia or lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jul-01, Volume: 20, Issue:13

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Camptothecin; Deoxycytidine; Drug Administration Schedule; Esophagitis; Evaluation Studies as Topic; Female; Gemcitabine; Humans; Infusions, Intravenous; Irinotecan; Leukemia; Lymphoma; Male; Middle Aged; Nausea; Neutropenia; Recurrence; Stomatitis; Treatment Outcome; Vomiting

2002

Other Studies

15 other study(ies) available for irinotecan and Lymphoma

ArticleYear
Risk factors for severe adverse effects and treatment-related deaths in Japanese patients treated with irinotecan-based chemotherapy: a postmarketing survey.
    Japanese journal of clinical oncology, 2013, Volume: 43, Issue:5

    Topics: Aged; Analysis of Variance; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asian People; Breast Neoplasms; Camptothecin; Colorectal Neoplasms; Death; Diarrhea; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Irinotecan; Japan; Leukopenia; Logistic Models; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms; Ovarian Neoplasms; Product Surveillance, Postmarketing; Risk Assessment; Risk Factors; Sex Factors; Skin Neoplasms; Stomach Neoplasms; Thrombocytopenia

2013
Genetically-engineered human neural stem cells with rabbit carboxyl esterase can target CNS lymphoma.
    Anticancer research, 2013, Volume: 33, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Base Sequence; Bystander Effect; Camptothecin; Carboxylesterase; Central Nervous System Neoplasms; DNA Primers; Genetic Engineering; Humans; Irinotecan; Lymphoma; Male; Mice; Mice, Inbred BALB C; Neural Stem Cells; Rabbits; Reverse Transcriptase Polymerase Chain Reaction

2013
Active targeting of chemotherapy to disseminated tumors using nanoparticle-carrying T cells.
    Science translational medicine, 2015, Jun-10, Volume: 7, Issue:291

    Topics: Animals; Antineoplastic Agents; Bystander Effect; Camptothecin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cytotoxicity, Immunologic; Drug Delivery Systems; Humans; Interleukin-2; Irinotecan; Lymph Nodes; Lymphoma; Mice; Nanocapsules; Nanoparticles; Receptors, Lymphocyte Homing; Sirolimus; T-Lymphocytes; Treatment Outcome

2015
Cellular backpackers deliver lymphoma drugs.
    Cancer discovery, 2015, Volume: 5, Issue:8

    Topics: Animals; Antineoplastic Agents; Camptothecin; Drug Delivery Systems; Humans; Irinotecan; Lymphoma; T-Lymphocytes

2015
Preclinical results of camptothecin-polymer conjugate (IT-101) in multiple human lymphoma xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jul-01, Volume: 15, Issue:13

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cyclodextrins; Female; Humans; Irinotecan; Lymphoma; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Polymers; Topoisomerase I Inhibitors; Treatment Outcome; Xenograft Model Antitumor Assays

2009
Human organic cation transporter 1 is expressed in lymphoma cells and increases susceptibility to irinotecan and paclitaxel.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 341, Issue:1

    Topics: Animals; Camptothecin; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Lymphoma; Organic Cation Transporter 1; Paclitaxel

2012
Tailored immunoconjugate therapy depending on a quantity of tumor stroma.
    Cancer science, 2013, Volume: 104, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Collagen; Female; Humans; Immunoconjugates; Irinotecan; Lymphoma; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Pancreatic Neoplasms; Topoisomerase I Inhibitors

2013
[A case of isolated hepatic malignant lymphoma representing characteristic findings on radiological imaging].
    Fukuoka igaku zasshi = Hukuoka acta medica, 2003, Volume: 94, Issue:11

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Irinotecan; L-Lactate Dehydrogenase; Liver Neoplasms; Lymphoma; Magnetic Resonance Imaging; Male; Neoplasm Recurrence, Local; Prednisolone; Tomography, X-Ray Computed; Treatment Outcome; Vincristine

2003
Proteasomal degradation of topoisomerase I is preceded by c-Jun NH2-terminal kinase activation, Fas up-regulation, and poly(ADP-ribose) polymerase cleavage in SN38-mediated cytotoxicity against multiple myeloma.
    Cancer research, 2004, Dec-01, Volume: 64, Issue:23

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Marrow Cells; Boronic Acids; Bortezomib; Camptothecin; Cell Communication; Cell Line, Tumor; DNA Topoisomerases, Type I; DNA, Neoplasm; Doxorubicin; Drug Synergism; Enzyme Activation; fas Receptor; Humans; Irinotecan; JNK Mitogen-Activated Protein Kinases; Lymphoma; Multiple Myeloma; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Pyrazines; Signal Transduction; Stromal Cells; Up-Regulation

2004
Expression of drug pathway proteins is independent of tumour type.
    The Journal of pathology, 2006, Volume: 209, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Breast Neoplasms; Camptothecin; Colonic Neoplasms; Cytochrome P-450 Enzyme System; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Immunohistochemistry; Irinotecan; Lung Neoplasms; Lymphoma; Male; Melanoma; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms; Tissue Array Analysis

2006
Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines.
    Investigational new drugs, 2007, Volume: 25, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzamides; Camptothecin; Carboplatin; Cell Line, Tumor; Cell Survival; Cyclophosphamide; Cytarabine; Depsipeptides; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Imatinib Mesylate; Irinotecan; K562 Cells; Leukemia; Lymphoma; Mercaptopurine; Piperazines; Pyrimidines; Time Factors

2007
The role of SN-38 exposure, UGT1A1*28 polymorphism, and baseline bilirubin level in predicting severe irinotecan toxicity.
    Journal of clinical pharmacology, 2007, Volume: 47, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Area Under Curve; Bilirubin; Camptothecin; Female; Glucuronosyltransferase; Humans; Irinotecan; Lymphoma; Male; Models, Biological; Neutropenia; Polymorphism, Genetic; Regression Analysis

2007
Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cytarabine; Deoxycytidine; Drug Interactions; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Hydrazines; Idarubicin; Irinotecan; Leukemia; Lymphoma; Sulfonamides; Topotecan

2008
4-Piperidinopiperidine-resistant lymphoma cells were resistant to dexamethasone- and A23187-induced apoptosis.
    Cancer letters, 1998, May-15, Volume: 127, Issue:1-2

    Topics: Apoptosis; Calcimycin; Camptothecin; Dexamethasone; DNA Fragmentation; Drug Resistance; Humans; Irinotecan; Lymphoma; Piperidines; Tumor Cells, Cultured

1998
An early phase II study of CPT-11: a new derivative of camptothecin, for the treatment of leukemia and lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Evaluation; Female; Humans; Irinotecan; Leukemia; Lymphoma; Male; Middle Aged

1990